LOCUS       DAIGWC010000001       122858 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.001, whole genome shotgun sequence.
ACCESSION   DAIGWC010000001 DAIGWC010000000
VERSION     DAIGWC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 122858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 122858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..122858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.001"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(324..1106)
                     /locus_tag="NOB74_000001"
     CDS             complement(324..1106)
                     /locus_tag="NOB74_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219221.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1171..2007)
                     /locus_tag="NOB74_000002"
     CDS             complement(1171..2007)
                     /locus_tag="NOB74_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1219222.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(2025..3434)
                     /locus_tag="NOB74_000003"
     CDS             complement(2025..3434)
                     /locus_tag="NOB74_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1219223.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(3448..5271)
                     /locus_tag="NOB74_000004"
     CDS             complement(3448..5271)
                     /locus_tag="NOB74_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1219224.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(6114..6440)
                     /locus_tag="NOB74_000005"
     CDS             complement(6114..6440)
                     /locus_tag="NOB74_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219225.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(6486..6848)
                     /locus_tag="NOB74_000006"
     CDS             complement(6486..6848)
                     /locus_tag="NOB74_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HCI1219226.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(6885..7099)
                     /locus_tag="NOB74_000007"
                     /pseudo
     CDS             complement(6885..7099)
                     /locus_tag="NOB74_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7227..7562
                     /locus_tag="NOB74_000008"
     CDS             7227..7562
                     /locus_tag="NOB74_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1219227.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(7638..9635)
                     /locus_tag="NOB74_000009"
     CDS             complement(7638..9635)
                     /locus_tag="NOB74_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219228.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(9733..10008)
                     /locus_tag="NOB74_000010"
     CDS             complement(9733..10008)
                     /locus_tag="NOB74_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1219229.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            10240..10974
                     /locus_tag="NOB74_000011"
     CDS             10240..10974
                     /locus_tag="NOB74_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1219230.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            11013..12155
                     /locus_tag="NOB74_000012"
     CDS             11013..12155
                     /locus_tag="NOB74_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI1219231.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(12250..13641)
                     /gene="sufB"
                     /locus_tag="NOB74_000013"
     CDS             complement(12250..13641)
                     /gene="sufB"
                     /locus_tag="NOB74_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HCI1219232.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(13646..14116)
                     /locus_tag="NOB74_000014"
     CDS             complement(13646..14116)
                     /locus_tag="NOB74_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HCI1219233.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(14103..15338)
                     /locus_tag="NOB74_000015"
     CDS             complement(14103..15338)
                     /locus_tag="NOB74_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI1219234.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(15335..16621)
                     /gene="sufD"
                     /locus_tag="NOB74_000016"
     CDS             complement(15335..16621)
                     /gene="sufD"
                     /locus_tag="NOB74_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HCI1219235.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(16634..17407)
                     /gene="sufC"
                     /locus_tag="NOB74_000017"
     CDS             complement(16634..17407)
                     /gene="sufC"
                     /locus_tag="NOB74_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HCI1219236.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(17604..18452)
                     /locus_tag="NOB74_000018"
     CDS             complement(17604..18452)
                     /locus_tag="NOB74_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI1219237.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(18476..19162)
                     /locus_tag="NOB74_000019"
     CDS             complement(18476..19162)
                     /locus_tag="NOB74_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1219238.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(19155..20189)
                     /locus_tag="NOB74_000020"
     CDS             complement(19155..20189)
                     /locus_tag="NOB74_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1219239.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(20252..20508)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(20584..20922)
                     /locus_tag="NOB74_000021"
     CDS             complement(20584..20922)
                     /locus_tag="NOB74_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HCI1219240.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(20924..21280)
                     /locus_tag="NOB74_000022"
     CDS             complement(20924..21280)
                     /locus_tag="NOB74_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HCI1219241.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(21286..22473)
                     /locus_tag="NOB74_000023"
     CDS             complement(21286..22473)
                     /locus_tag="NOB74_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCI1219242.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(22664..23509)
                     /locus_tag="NOB74_000024"
     CDS             complement(22664..23509)
                     /locus_tag="NOB74_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1219243.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     HLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTKRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            23743..24708
                     /locus_tag="NOB74_000025"
     CDS             23743..24708
                     /locus_tag="NOB74_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HCI1219244.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            25085..26128
                     /locus_tag="NOB74_000026"
     CDS             25085..26128
                     /locus_tag="NOB74_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HCI1219245.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(26190..26654)
                     /locus_tag="NOB74_000027"
     CDS             complement(26190..26654)
                     /locus_tag="NOB74_000027"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HCI1219246.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            26900..27847
                     /locus_tag="NOB74_000028"
     CDS             26900..27847
                     /locus_tag="NOB74_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI1219247.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(28058..30130)
                     /locus_tag="NOB74_000029"
     CDS             complement(28058..30130)
                     /locus_tag="NOB74_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI1219248.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(30063..30440)
                     /locus_tag="NOB74_000030"
     CDS             complement(30063..30440)
                     /locus_tag="NOB74_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HCI1219249.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(30569..31147)
                     /locus_tag="NOB74_000031"
     CDS             complement(30569..31147)
                     /locus_tag="NOB74_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1219250.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            31279..32571
                     /locus_tag="NOB74_000032"
     CDS             31279..32571
                     /locus_tag="NOB74_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI1219251.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(32631..33749)
                     /locus_tag="NOB74_000033"
     CDS             complement(32631..33749)
                     /locus_tag="NOB74_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HCI1219252.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(33763..35184)
                     /gene="arcD"
                     /locus_tag="NOB74_000034"
     CDS             complement(33763..35184)
                     /gene="arcD"
                     /locus_tag="NOB74_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HCI1219253.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(35430..36551)
                     /gene="mnmA"
                     /locus_tag="NOB74_000035"
     CDS             complement(35430..36551)
                     /gene="mnmA"
                     /locus_tag="NOB74_000035"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HCI1219254.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            36955..37554
                     /locus_tag="NOB74_000036"
     CDS             36955..37554
                     /locus_tag="NOB74_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HCI1219255.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(37692..38978)
                     /gene="efmA"
                     /locus_tag="NOB74_000037"
     CDS             complement(37692..38978)
                     /gene="efmA"
                     /locus_tag="NOB74_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HCI1219256.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(39249..39593)
                     /locus_tag="NOB74_000038"
     CDS             complement(39249..39593)
                     /locus_tag="NOB74_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HCI1219257.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(39730..40875)
                     /locus_tag="NOB74_000039"
     CDS             complement(39730..40875)
                     /locus_tag="NOB74_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI1219258.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(41055..42029)
                     /locus_tag="NOB74_000040"
     CDS             complement(41055..42029)
                     /locus_tag="NOB74_000040"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCI1219259.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(42109..42984)
                     /locus_tag="NOB74_000041"
     CDS             complement(42109..42984)
                     /locus_tag="NOB74_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HCI1219260.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            43114..45021
                     /locus_tag="NOB74_000042"
     CDS             43114..45021
                     /locus_tag="NOB74_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HCI1219261.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(45562..48840)
                     /locus_tag="NOB74_000043"
     CDS             complement(45562..48840)
                     /locus_tag="NOB74_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HCI1219262.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(49111..49656)
                     /locus_tag="NOB74_000044"
     CDS             complement(49111..49656)
                     /locus_tag="NOB74_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI1219263.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(49668..50360)
                     /locus_tag="NOB74_000045"
     CDS             complement(49668..50360)
                     /locus_tag="NOB74_000045"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HCI1219264.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(50379..50663)
                     /locus_tag="NOB74_000046"
     CDS             complement(50379..50663)
                     /locus_tag="NOB74_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219265.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(50676..51239)
                     /locus_tag="NOB74_000047"
     CDS             complement(50676..51239)
                     /locus_tag="NOB74_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI1219266.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            51467..52129
                     /locus_tag="NOB74_000048"
     CDS             51467..52129
                     /locus_tag="NOB74_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HCI1219267.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            52253..53449
                     /locus_tag="NOB74_000049"
     CDS             52253..53449
                     /locus_tag="NOB74_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HCI1219268.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(53550..54926)
                     /locus_tag="NOB74_000050"
     CDS             complement(53550..54926)
                     /locus_tag="NOB74_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1219269.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(54963..55829)
                     /locus_tag="NOB74_000051"
     CDS             complement(54963..55829)
                     /locus_tag="NOB74_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HCI1219270.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(55918..56943)
                     /locus_tag="NOB74_000052"
     CDS             complement(55918..56943)
                     /locus_tag="NOB74_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI1219271.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(56961..57635)
                     /locus_tag="NOB74_000053"
     CDS             complement(56961..57635)
                     /locus_tag="NOB74_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1219272.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(57819..58712)
                     /locus_tag="NOB74_000054"
     CDS             complement(57819..58712)
                     /locus_tag="NOB74_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1219273.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(58786..60483)
                     /locus_tag="NOB74_000055"
     CDS             complement(58786..60483)
                     /locus_tag="NOB74_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI1219274.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(60476..61789)
                     /locus_tag="NOB74_000056"
     CDS             complement(60476..61789)
                     /locus_tag="NOB74_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCI1219275.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(61789..65826)
                     /locus_tag="NOB74_000057"
     CDS             complement(61789..65826)
                     /locus_tag="NOB74_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCI1219276.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(65839..66297)
                     /locus_tag="NOB74_000058"
     CDS             complement(65839..66297)
                     /locus_tag="NOB74_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI1219277.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(66595..67113)
                     /locus_tag="NOB74_000059"
     CDS             complement(66595..67113)
                     /locus_tag="NOB74_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCI1219278.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(67115..67732)
                     /locus_tag="NOB74_000060"
     CDS             complement(67115..67732)
                     /locus_tag="NOB74_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HCI1219279.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(67729..68583)
                     /locus_tag="NOB74_000061"
     CDS             complement(67729..68583)
                     /locus_tag="NOB74_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1219280.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(68580..69491)
                     /locus_tag="NOB74_000062"
     CDS             complement(68580..69491)
                     /locus_tag="NOB74_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1219281.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAVSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(69532..70866)
                     /locus_tag="NOB74_000063"
     CDS             complement(69532..70866)
                     /locus_tag="NOB74_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1219282.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            71074..71904
                     /locus_tag="NOB74_000064"
     CDS             71074..71904
                     /locus_tag="NOB74_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCI1219283.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(72148..72430)
                     /locus_tag="NOB74_000065"
                     /pseudo
     CDS             complement(72148..72430)
                     /locus_tag="NOB74_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011066964.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(72588..72782)
                     /locus_tag="NOB74_000066"
     CDS             complement(72588..72782)
                     /locus_tag="NOB74_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219284.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(73385..74511)
                     /locus_tag="NOB74_000067"
     CDS             complement(join(73385..74283,74283..74511))
                     /locus_tag="NOB74_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI1219285.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(75574..75915)
                     /locus_tag="NOB74_000068"
     CDS             complement(75574..75915)
                     /locus_tag="NOB74_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI1219286.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(75915..76145)
                     /locus_tag="NOB74_000069"
     CDS             complement(75915..76145)
                     /locus_tag="NOB74_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI1219287.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            76432..76770
                     /locus_tag="NOB74_000070"
     CDS             76432..76770
                     /locus_tag="NOB74_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219288.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(76975..77214)
                     /locus_tag="NOB74_000071"
     CDS             complement(76975..77214)
                     /locus_tag="NOB74_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCI1219289.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTVISFARKIITQQMPELVMEKV"
     gene            complement(77190..77537)
                     /locus_tag="NOB74_000072"
     CDS             complement(77190..77537)
                     /locus_tag="NOB74_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCI1219290.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(78269..78850)
                     /locus_tag="NOB74_000073"
     CDS             complement(78269..78850)
                     /locus_tag="NOB74_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1219291.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(79033..79659)
                     /locus_tag="NOB74_000074"
     CDS             complement(79033..79659)
                     /locus_tag="NOB74_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI1219292.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(79681..81012)
                     /locus_tag="NOB74_000075"
     CDS             complement(79681..81012)
                     /locus_tag="NOB74_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HCI1219293.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(81167..81568)
                     /locus_tag="NOB74_000076"
     CDS             complement(81167..81568)
                     /locus_tag="NOB74_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI1219294.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(81654..81860)
                     /locus_tag="NOB74_000077"
     CDS             complement(81654..81860)
                     /locus_tag="NOB74_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219295.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(81955..83457)
                     /locus_tag="NOB74_000078"
     CDS             complement(81955..83457)
                     /locus_tag="NOB74_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HCI1219296.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(83475..83930)
                     /gene="argR"
                     /locus_tag="NOB74_000079"
     CDS             complement(83475..83930)
                     /gene="argR"
                     /locus_tag="NOB74_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCI1219297.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(84028..84645)
                     /locus_tag="NOB74_000080"
     CDS             complement(84028..84645)
                     /locus_tag="NOB74_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HCI1219298.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            84866..86239
                     /locus_tag="NOB74_000081"
     CDS             84866..86239
                     /locus_tag="NOB74_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1219299.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            86314..87426
                     /locus_tag="NOB74_000082"
     CDS             86314..87426
                     /locus_tag="NOB74_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCI1219300.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(87498..89135)
                     /locus_tag="NOB74_000083"
     CDS             complement(87498..89135)
                     /locus_tag="NOB74_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HCI1219301.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(89303..89911)
                     /locus_tag="NOB74_000084"
     CDS             complement(89303..89911)
                     /locus_tag="NOB74_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI1219302.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(90295..91446)
                     /gene="queG"
                     /locus_tag="NOB74_000085"
     CDS             complement(90295..91446)
                     /gene="queG"
                     /locus_tag="NOB74_000085"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HCI1219303.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(91465..92217)
                     /locus_tag="NOB74_000086"
     CDS             complement(91465..92217)
                     /locus_tag="NOB74_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219304.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(92358..93308)
                     /locus_tag="NOB74_000087"
     CDS             complement(92358..93308)
                     /locus_tag="NOB74_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCI1219305.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(93309..94148)
                     /locus_tag="NOB74_000088"
     CDS             complement(93309..94148)
                     /locus_tag="NOB74_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI1219306.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(94145..94891)
                     /locus_tag="NOB74_000089"
     CDS             complement(94145..94891)
                     /locus_tag="NOB74_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI1219307.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            95129..96499
                     /locus_tag="NOB74_000090"
                     /pseudo
     CDS             95129..96499
                     /locus_tag="NOB74_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(96554..97450)
                     /locus_tag="NOB74_000091"
     CDS             complement(96554..97450)
                     /locus_tag="NOB74_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI1219308.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(97564..97734)
                     /locus_tag="NOB74_000092"
     CDS             complement(97564..97734)
                     /locus_tag="NOB74_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219309.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(97731..98408)
                     /locus_tag="NOB74_000093"
     CDS             complement(97731..98408)
                     /locus_tag="NOB74_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCI1219310.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(98499..99404)
                     /locus_tag="NOB74_000094"
     CDS             complement(98499..99404)
                     /locus_tag="NOB74_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI1219311.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            99579..101003
                     /locus_tag="NOB74_000095"
     CDS             99579..101003
                     /locus_tag="NOB74_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1219312.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            101049..102080
                     /locus_tag="NOB74_000096"
     CDS             101049..102080
                     /locus_tag="NOB74_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI1219313.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            102087..103274
                     /locus_tag="NOB74_000097"
     CDS             102087..103274
                     /locus_tag="NOB74_000097"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HCI1219314.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            103430..104812
                     /locus_tag="NOB74_000098"
     CDS             103430..104812
                     /locus_tag="NOB74_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCI1219315.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            104939..105169
                     /locus_tag="NOB74_000099"
     CDS             104939..105169
                     /locus_tag="NOB74_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219316.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(105369..106037)
                     /locus_tag="NOB74_000100"
     CDS             complement(105369..106037)
                     /locus_tag="NOB74_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HCI1219317.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(106226..107023)
                     /locus_tag="NOB74_000101"
                     /pseudo
     CDS             complement(106226..107023)
                     /locus_tag="NOB74_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(107304..108683)
                     /locus_tag="NOB74_000102"
     CDS             complement(107304..108683)
                     /locus_tag="NOB74_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI1219318.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(108858..110027)
                     /locus_tag="NOB74_000103"
     CDS             complement(108858..110027)
                     /locus_tag="NOB74_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI1219319.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(110002..111153)
                     /locus_tag="NOB74_000104"
     CDS             complement(110002..111153)
                     /locus_tag="NOB74_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCI1219320.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(111113..112474)
                     /locus_tag="NOB74_000105"
     CDS             complement(111113..112474)
                     /locus_tag="NOB74_000105"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HCI1219321.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(112471..113472)
                     /locus_tag="NOB74_000106"
     CDS             complement(112471..113472)
                     /locus_tag="NOB74_000106"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCI1219322.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(113488..114183)
                     /gene="dapD"
                     /locus_tag="NOB74_000107"
     CDS             complement(113488..114183)
                     /gene="dapD"
                     /locus_tag="NOB74_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HCI1219323.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(114189..114905)
                     /locus_tag="NOB74_000108"
     CDS             complement(114189..114905)
                     /locus_tag="NOB74_000108"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HCI1219324.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(114902..115783)
                     /locus_tag="NOB74_000109"
     CDS             complement(114902..115783)
                     /locus_tag="NOB74_000109"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCI1219325.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(115786..116586)
                     /gene="dapF"
                     /locus_tag="NOB74_000110"
     CDS             complement(115786..116586)
                     /gene="dapF"
                     /locus_tag="NOB74_000110"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HCI1219326.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(116573..117832)
                     /gene="lysA"
                     /locus_tag="NOB74_000111"
     CDS             complement(116573..117832)
                     /gene="lysA"
                     /locus_tag="NOB74_000111"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HCI1219327.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(118047..118217)
                     /locus_tag="NOB74_000112"
     CDS             complement(118047..118217)
                     /locus_tag="NOB74_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219328.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            complement(118318..118881)
                     /gene="efp"
                     /locus_tag="NOB74_000113"
     CDS             complement(118318..118881)
                     /gene="efp"
                     /locus_tag="NOB74_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HCI1219329.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            119309..120226
                     /locus_tag="NOB74_000114"
     CDS             119309..120226
                     /locus_tag="NOB74_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HCI1219330.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            120239..121384
                     /locus_tag="NOB74_000115"
     CDS             120239..121384
                     /locus_tag="NOB74_000115"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HCI1219331.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            121555..122013
                     /locus_tag="NOB74_000116"
     CDS             121555..122013
                     /locus_tag="NOB74_000116"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HCI1219332.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            122172..122642
                     /locus_tag="NOB74_000117"
     CDS             122172..122642
                     /locus_tag="NOB74_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HCI1219333.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(122695..122810)
                     /gene="rrf"
                     /locus_tag="NOB74_000118"
     rRNA            complement(122695..122810)
                     /gene="rrf"
                     /locus_tag="NOB74_000118"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        35243 a        25750 c        21700 g        40165 t
ORIGIN      
        1 gttatcttta gaaccatttc agatacatat gaaacaatta catatgattt tttcataaaa
       61 aaacagtact gtctagtagt ataaaatata caaatttctt aaaaattttt tcactaaaat
      121 cactacctga aacagtctaa aacacttata tatcaacgtt taatgaaact atctccgttt
      181 catttcagat acaaataaat atagtcgggc tccaaatccg aaaaaaaata cccccagtag
      241 cttatcctaa gctactggag atgtataagt acggtcatat aacaacgggg tagggtaaat
      301 aaatgaaaaa gatggaagaa tcattattca ataacttttt taaatacttc gttgtaatca
      361 gttacctgtc cgttcttaaa taccacagaa taatcttttt tcccattttc aagtaaccga
      421 agtggaatgt ctttaccaac ttgctctgtc actgcattac tgatacctgt tagattagct
      481 aataaatctg ataaagattg agcatctgta gaaatctctg tatcagtatt tatcgtgatt
      541 cctttatctt catttacaag cttccaagta ggtggtatag ctgtgtatgt ttcgatgaat
      601 gaatcaattc tttcatctat cgtcttccca gtatctactt ctgtctcatt actcttagat
      661 gaatcgattc tttcatccat cgtctgctcc gtaactgctt ctgtctcatt attctcaccg
      721 gaaactctct tcacacccaa acttatatat tgtccatctt tagtgtgcat agttaaaatt
      781 cccacgcttt tactaataaa ttcactataa ccagttcttt caatagagac ttcaatgtat
      841 ttcacactat catactcaaa agaaaaatag acatgtaaaa gcattttgtt gtttacatct
      901 acataataat cctttgactc tacttgagac cttcctatac ggaatacagc tttactgtct
      961 gatatctcta taccagcatc cttattatta atctgccaat ctccaagtag ctcttctggc
     1021 aagctagtag tttcttgtga acactttacc acttcactgg tagaggtcga aacattcacc
     1081 tccgcactgt tagaagaatt ttccaaggaa tcaggagcct tagcacaacc aacaagtctt
     1141 tatatattgt gcagccgata ttttcttcat tcagtacacc cttgaaatat gcagtgttag
     1201 ataaagcagt tcgtcctgat ttgctgaggc acccatctct tcttgaacgt actccttgat
     1261 tttcaaggcc gcccgatact ctttcggaaa acgctgcttc actgaagcca gcaaaaaatc
     1321 atccttctcc ggcaactctt ccttcttaat cattcgggca ataaaaaact gtaaatgcgt
     1381 cacaaatctt aagtaaagca tcgaatcttt atcaaccttt ttttcgggaa acagatatcc
     1441 tagcatagcc aagatatcct ttagtgctct taccgagagc atggtttctt ccatatttgc
     1501 ttgttcactt tgggcattta caatgtgaaa cgcaatgttt ccagcctcct cttctggcaa
     1561 ctgaacattc atttttttgt tgatcaattg gatagcatag cagccgatct caaattcttt
     1621 tgggtaatac ttttgaattt caatcagcag gcgattttga aaaacaatgc ctttttgact
     1681 gcgttcaatg gcatgcttca agtgatcaac caaggtaaaa aatagacttt tattcagctt
     1741 aaagtcaaac ttggcgttgg cataatcgat aattcgcttg acgcaaataa ttagatcatc
     1801 cggagcagcc tcaaacagtt taatgtaatc cttttttaga gcatcagaaa gtgaatctaa
     1861 tttaaatact ttttggattt tgtcagccgg aaccaaatcg cctttcttta gttgaaatcc
     1921 aatccctttc cccatcaaaa ttacttcttt gccttgctta tctaagcaaa gaattaaact
     1981 gttgtttaac gttttaatta ctctcattag attcaccgtt ctctctaagc taagccattt
     2041 cttgcgatta ctttttgata ccaaaagaag ctttcttttt ttattcgttt taattcttta
     2101 agattctcat cggttcggtc aacatatata aaaccataac gcttattgaa gccttgatgg
     2161 gtactaacaa catcaatcgc tgaccaaggt aaataaccaa aaacatctac accatctgtt
     2221 aaagctgctt gaatagccag aatatgtttg gctagataat caattcgatc ctggtcatta
     2281 attcgtctat cttcctcaac tatgtcgggt gccccatagc cattttcagt aattaaaata
     2341 ggtaaatcat agcgatcgta caatttcctc aatgttaatc gtagtccagt agggtcaact
     2401 acccagccat atggcgtttt atctacataa ggattttcag ctgcccggta gacaccttct
     2461 tctcccaaca tgatctgttg atcccccgct ctagcggaaa catctgatcc gtcatttttg
     2521 ctggcagcga tggtggcagt tgaataataa ttaatcgcaa taaaatcggg tttaccggag
     2581 gataaaattg cctgatcctc tgcctcaatt ttaggatata atccacgatc attcaaatag
     2641 ttttcaaaca aataattgta ttttccccga actgctacat ctaagaaaga ccagcctctc
     2701 aatgtttccc aattatgggc tgcaattgca tcttctggac tggaggtagc ttgatacata
     2761 gccgttaaat tgattgctgg accgattttt cctttaagat tcaactgatg atacaagtga
     2821 attactctag cttgagctaa taaaacatgg tgattaattt gaaagagttc tttttttgaa
     2881 ggcagctctc cacttggtgg caaaccaatc gctccaggat gaaggatcat cgtgttttgc
     2941 tcattaattg tcagccaata gttcaccttg tcaccatact cagtaagcaa tacctgtaca
     3001 tagtccacaa aataatcgat agttgctcga tttaaccaac cgccctgctc ctctagaaaa
     3061 taaggtaaat cgaaatggta catggtgaca atcggttcga ttccctgatt caggcattca
     3121 tcaattactt gatgataaaa agaaattccc ttttgattgg ttttattatt ttcaatatcc
     3181 ataattcgcg tccaagcgat ggaaaagcga aaagctttta agcctaattc tttaaacagc
     3241 tgtatatctt ctttatagtg atggtaaaaa tccgaggcaa cttcaaaatt agctacccct
     3301 tctgtatgct gatacttgtc aataatagac ggttgtttcc catcctcctg ataggcaccc
     3361 tctgcctggt aggcactaat ggaggcaccc cataaaaact tctctggaaa tgctgaaagc
     3421 tgtttgtatt gcacaaaaat cctctcctta actaatttgc atcaatggtt cgtgttcctt
     3481 taagcttccg cttgcttcac taattcctgc gtaattttca ctgttggtca ctaccacaat
     3541 cactgtatca tcgtagccag cgtttctaat ggcagcgaaa tcggcgttga ttaataattg
     3601 tcctgctgac acctgatctc ctgcttttac aaatacttca aagggttccc cttttaaatt
     3661 cacggtgtcg atccccacat ggatcaataa ttcaatacct tctttagaac gtagaccaat
     3721 cgcatgttta gattctaaaa tagtaatgac ttctccctca acaggtgaat aaatgctgtt
     3781 ttcttctgga tgaatggcta cgccctttcc caatagtccc ttagaaaaga cagcatcgtt
     3841 cacttcagaa ataggacaca cggttccttt taccggattt tcaacaatga ctgcttcggc
     3901 tattgccgtt tgctctgatt catcagaagt atcgtcaaat ccaattagat aagcaatgat
     3961 aaaggttgca acaaaggcga ttacacacgt aataattgcg tgaacaatat tcattggatt
     4021 ttctccaata aaggctggta aggctgctaa gccaggggaa acaaaggcat atctgactaa
     4081 accgctcaag ccagcataca aaccagcaat tgcaccacca atcatggaag caactaatgg
     4141 ttttttcagc ttcaaggtta ctccatagag tgaaggctca gtaattccca ttaaagcagt
     4201 gatcccagtg gacacagcta gctgcttcaa ctctttgttt ttagttttcg cggctacagc
     4261 aaaggtagca cctgattgag caatattaga agccagcatt cctggcccat tgatcatttc
     4321 agaacccgta ctgctcaatt gcatagtagc gattggcgtc attgcccaag ctgtacccgt
     4381 aaccaccaaa aatggctgca aaccacccat caaaaatgga attaaccaag ctgctttgcc
     4441 gttaatccat tcagccccca ttgctataag atcgttcagc aacgttccaa acggtccaat
     4501 gacaaccaac gctaaaggcc ccataattaa aaataccagc atcggcttag taaagaattt
     4561 aataaacgaa ggcgaaattc gatccgcaaa gggctctaca taggacatga tccaaacagt
     4621 aaagataatc ggtaaaactg atcccgcata atctgcagct aataccggaa ttcctagaaa
     4681 agaaacggca tcgccagtag aaaaaagctg tgaaatattt ggatgaagca aaatgccagc
     4741 aacagtaatc gccaaaattg ggttgacatc aaactttatg gctgccccat aggctaatag
     4801 tactggcata aaataaaagg ctgcatcagc aatagtattc aaaatgatgt aagtttgact
     4861 actgtctgat agtacaccag tcaaagtcaa gacggccaaa atggctttta ccatcccggc
     4921 acctgttata gctggaatca tcggtgtaaa ggtggtagaa atgacactaa tcaatcttga
     4981 aataatactt tcttgattgt ctgaagaggg gcccttttta attgaagttc ccacttcctt
     5041 ttgaatttcc ttgaaggctg tttggacttc attgccaatc accacttggt attgtccacc
     5101 gctatccacc acactaatta caccaagtgt tttttctaag gctttcgtat cggctttcct
     5161 tttatctttg agttcaaaac gcagtctggt ggcacaatgg gttaagctga ccacattttc
     5221 ttttccccca acctgttgca atacatttct tcctacttct ctgtaatcca ttattctctc
     5281 tccttaaagc agtaaaaaag accaagtcaa accacgcccc aatcaacatt gaagtgttag
     5341 tttgtcttgg tcttgcctgc ataatcagta acatgccaat aacgttattt tgctgtaatc
     5401 caataatagc acattatgat agcgcaatca acagggaatt taatttttta tcttttcgtt
     5461 tgaccgtata gggtaatata acagttagat cacatcaact agggtatatc tgcgtatact
     5521 tactgctaaa ataagtatat ctaatattaa ctataccagt aaaaccattc ctacataacc
     5581 agcgggaaat tcccaaaatc gtgaaagcat caaaaatgca tataacggat cacacaactt
     5641 caacaattct gctcttggga aaaattgatg aatttggtga gtaaaggatg gaataaacag
     5701 cattccaaca atataggcaa caatagtgat acttgttttt ttggtaaaaa tcagtaagca
     5761 atagccaatt tcaatcattc cgagatataa aggtatcgat agaatgattt gggctagtat
     5821 tcttaaaaat taactagcaa atgtttaaac tgatttattt ctaatctaca tgtagtaagt
     5881 atttcaattc caccaattat caataaaaat accaaacata tccataataa ttttttcttt
     5941 ttcatttctt ttatattgtt ataacagtga ataacataaa aattcccgac aatcattgta
     6001 atattttttt gtcacctgta ttagtattta atttatagga aactataaaa actccctagt
     6061 gaatttacac ctttgggagt tcctgtttgg acggtatgca taatacattt aaatcaattt
     6121 aacattaaca cctcagcata tggtatctcc acatatatac ggtctttctt tggatagtac
     6181 tcaatattta tgttgatagc acttccattg tctaatatag ctttagcccg gtatgtgtta
     6241 tctccatttt catgagtaat cgtcacatca tcacatgatc gatttaagtt gtactgttct
     6301 tgtaaaatct gtgttaccaa tggtttcgat gacttctcta atccagatgt acctgtcatt
     6361 tttgaaaaaa tgatacctat aatagccaag acaacgataa ctataatgat aaacttcttg
     6421 ttcatattta ctttattcaa ctttttatct cctatctcca aaataatttg ctcttatccc
     6481 tcttatcagt acattgacat ccctaaaagt acaccaaaga ttgctccagc tacccctgct
     6541 atcatcaaaa tcgtacccat ttgttcatct ttatctcgat ataagtagcc cataataaca
     6601 gcaacagcac caaatacaac aggaataaat gctaacgcta ctaccataga aatccaacca
     6661 ataatcaaat acagcttccc tgtctcttgt ccatgtacga tttgttcctt catttcatta
     6721 attgtctgct cagtactttt ctttactgcg tctgctccag ttgtctcatc tgtttcttgt
     6781 agtgctccgc aaaactggca atacttactt tcatctgtta tttctttgcc acattttcta
     6841 caatacatgt cttctcctcc taaaaacatt caattgttta ttagttaact gtttacttta
     6901 ttaaatacat cagaaaacag ctcattcatt ggtacactta atatctcaga aagcatcttc
     6961 atttgatagg gtttaggaat cgttctccct gtttgccacg aacttacaca ttgctgtgta
     7021 acattcattt ttttgctaac tccgtttgag aaagtccttt ttcttttctg tatcggctga
     7081 gattacttac ttttttcatg attctcccct cctgttttat tatatacaac aatatgatgt
     7141 atttcaactc ataaaatata aaaaaacttc aaataccatt acaaatacaa caacttgttg
     7201 tactatactg agatgggggt gtattaatga aacagaaaca atatgcaaag gtcattagag
     7261 aaaagcgaaa agctctcggg tggacacaaa aagaattagc tgaaaaaatc ttctctacac
     7321 aacaggcagt agcaagatgg gaaaattctg taacagagcc taacctcgat agcttaaccg
     7381 ctctttctag agccctagga acccctgtaa gccattttct agacaatgtt gtcgtagatt
     7441 atgaggaaga gtttttggct ctctatcgtt ctcttagcac tgaagatgca gttcgaacaa
     7501 ttgactatat gaagctatta aaaaggcaag aaaatgaacg caatcagcta ttgaaagatt
     7561 gaaaaataaa taacccaccg aactttaacg gtgggtgtat tgagatgaaa taagattaag
     7621 agctatggat aacctgtcta gtttaataca attgggtctt ttctcttcct tactctccgt
     7681 ccatcatctc ttgttacact tgtaaattga taaagaggaa ctaattcaac tcctgataat
     7741 atcaattctt ttattacttc atctatccct gctccttttg ctaggtagac taaaaaacta
     7801 ctacttgctt tcacattgta tagtctctta atatccttag aagctcgttc aagagtgaat
     7861 ccttgtttaa caaagtagcc tctgttttct tttaaagcat tttccacgct gttattccca
     7921 acattacgta gacgttcaca aacagtgtta gtaagttctt tctctgtcat tagatatgtt
     7981 ccttgccacg ataagccctg taaaacttca tgtgcttcat ctaaaatcaa ttgtttttcc
     8041 ttgctaagtt ctgatcggga attttgagga aatactcttt tagcctcttt ttcgttaaaa
     8101 catatcttaa cccattcata agaaaaatat tgatatgtaa aatgaaattt ttccagaagt
     8161 ggaaggatat cttcattcaa tttttgaatc acagaagttg cattaaaaac gtctaatcga
     8221 tagacattgc ttctcttatg attaaagttt cctaacgctt tctcttcctt taacctattt
     8281 aggtattcga gcatcttcaa aggaacatct tcatcatcta atttttttat caatcctata
     8341 aaagtcataa gtgatagtaa cttattacat ttatctatgt cataagtttt accatagtaa
     8401 aaactcattt ttttagctaa ttgttccccc gacaaaatac aagtcacact ttccttacta
     8461 tcatcaaaaa aattaacatc agaaagcaag acatcataga cacgtcgcat ttcctctaga
     8521 taattcctta ttgtcctgaa aagtttgtct ttcattgatt caagagtgtc aaaaagtact
     8581 tttgattcct ctttcaattt tcgaaaatgt gtaggataca agtctaggtt ctctaatagc
     8641 caattaaatg tttctacccg actgtctttc tttaaaatta gcatcacaac tccaataaaa
     8701 ttttcactga tatcacaatt actggaatga caataaaaaa tggaatgccc agttttactg
     8761 gtaaaaatac tagcagaggg attatgatcg ttgtgaaaca gacatcttaa gtttttactt
     8821 gacttaagta atttattcat atcaatggtt aacaatcttt cataaatctc attaaaagac
     8881 atgtcggagg aatcaaacag gcagtcttta aaccactgtt tcatttcttc tttgtcgtca
     8941 ttttttatca acttaacaaa atcggtttca ttgactagtt catactctct ccctgaatca
     9001 ctttgacaat ttttagaaca tgtcatggta aaatcaatcg gaagctcagt aatatctaac
     9061 atgttgtctt cattaattat tatcactgca tctgacttat atcctccaaa aaacattcta
     9121 ttcgaagcat ttacattgtc atcacacccg gggatgttct ttttcaagta ttcgtaaaca
     9181 gcaaccattt taccatagtc agtaattgct tcttttaata gaaagacaat cttgtatttt
     9241 tctagatttt cagagtaccg aatacttttt tgtatcgcaa acgcagaatt atgaactaaa
     9301 ttgatagata aaaccttttc tatgcttaag tatctactat catctttact caaatctact
     9361 accttcccct tctcatcttt aacagtgtta tcgacatcca gaataattac tctggtttcc
     9421 acaaaactct ccttgtcatt gcctttattc tttgtcttgc ttggaataaa tgattgtgat
     9481 gaatttagta tctctacaaa ctcatctctt gtaacttctc tatagttatc taaacaccta
     9541 tctcttacat cagttttttc tttttttgta actggcttct ctaataattt ttctttatct
     9601 acataaattg gaatattaat cattgatgtt tccatttgtg tttcctcctt ataaaattct
     9661 gttaaagact aaaacataca gataataaaa acaaactctt tattactata tgttttagtc
     9721 ttatttgttt actcaacctt tataccgttc catgaaacta tcaatatcag attttttaaa
     9781 tctaatgacc gtatcaattt ttataacagg taacccgtat tgagaaacat attttctaat
     9841 cgttcctact gatacaccta gatattcact tgcctgctga tagtccatat actctagagt
     9901 gactccagaa ataatgtctt ctagcatagg ctttagcact gtaattatct ctttcacttg
     9961 ttgttcaact tgtatagaaa caatgctatc aatgatttgt agagacatat ttccccctcc
    10021 tttcgtgatt gcttgaacaa attttctaag aattatcttc gtattttttg ctcaaaataa
    10081 aagtattttg ttattaaccg attaatcaaa caaaaaatga ttaccagttc atcgacatac
    10141 acataatacc tcgataaaaa agaggtgtca atatctttgt aaaatttatt tacaacaccc
    10201 ctttttcgag gtatactaat tttaggaggt gtggtcaata tgataaaacg tccaccaata
    10261 aattatttag aacgaaaaaa gatactcgga acaaaaataa aagctataag aaagagtaaa
    10321 aaattaacac aaccagcatt tggtcttatg attaacaacg gtcaattaat tgacaaaaaa
    10381 actatctacg aatgggagaa gggaacctat ttaccaatac cagagcgatt atcccgaatt
    10441 gctgatttgg gaaatatgag tatagaggag ttagtttgtg gcaatgtaga agaatatatt
    10501 ttgggaatta ttctttatag agatagcatt gtactagatg gtataacatt tccagataaa
    10561 aacctgttcc agcatcttcg tcaacagttc ccaccagtac actctaattt agatacatgg
    10621 ctggatagat attccaaatt agaaccagag atgcaagaat ttattgctaa caagacttgt
    10681 aataaagtta aaaatgaaaa aattagtctt ttcaatatct taaaaataga agaattattc
    10741 atcaatgcta ttgtagaaga atttgacaat aacattcttt tcctcactag cagtatagaa
    10801 gaactactag aaagaatggt agatgaatgg ctacctattc aattgaaaga catgtcttat
    10861 cccgaagaag ctgtgagaga aattactgat aatataaaca agctagaaca aacgatttca
    10921 tcaattggga aaaaatacac taagaaaaaa atgaagggag gtgataccat ctagtggtaa
    10981 gtactccttg taaactaaga ggagatgatt tcatggcaaa aatatcaaag tacaaaaaga
    11041 aaaacggtca agtggcgtgg atgtataaag gacacattgc caccgatcca cgaactggtg
    11101 aaaaaataaa tactacgaga agaggtttta gtagcaaaca agaagctcaa aaagattatg
    11161 acgagtacag acatcaaata ttatacggtg ttaaaaagaa agcacctgat atgacatttg
    11221 aagacctgta taatgaatgg ataactcatc agcgtaccag tgttaaagct tcaacaatcg
    11281 caatctcagt aagatacgca aataatcaaa tacttccagc atttggtaag cttaaactat
    11341 cgaatatctc tgtcccatat tgtcaaaaag tggtagatga atggcacagt aaatatgaaa
    11401 gttacgatta tatgagaaaa cagactgcac aaattttacg ctacggggtt gcaatgcaat
    11461 atattgacaa taatcctatg gaaaaaacac ttcttccacg aaaaaaagag tatgagaaaa
    11521 atcgtaaatt ttactcaaaa gaggagctta ataatttact ggatgctttt aaagattttg
    11581 gtaacatgaa acaatacgcc ttcttcagat tattggcata cacaggtatg agaaagagtg
    11641 aagtactcgc tttacagtgg aaagacatag acacgtttaa taaagaacta catgtcaata
    11701 aaactcttgc tgtagatgaa tttggtaaag ttataattca atctccgaaa acaagagctt
    11761 ctagacgagt tatctcttta gatactgaga ctctttctat cctcaacaac tggaaattac
    11821 agcaaaaaga agagtattta aaacttggat acaatactag ctctaaagag caacatgttt
    11881 ttacaacagt taaaaacact ctatacattc caaacactgt taatgattgg ttaagatata
    11941 ttttgaaaaa atataacttg cctcgtatta cacctcatgg gtttagacat acacatgcta
    12001 gtttattatt agaagcagga gaatctgtca aggtagttca acaacgatta gggcatgaaa
    12061 atagtaaagt gacattagac atctatgcac atattacaaa taatgcacct aagaaaacag
    12121 gtcaagactt tgctgatatg atggctcatc agtaaaagag ctggtcaaaa tctggtcatt
    12181 tctagtatac aggcaaaaca aaaaagctag aacccttata tatcaagggt tctagctcct
    12241 ataacaggtt tacccaacac tgccttccat ctcataactg atcaatcgat tgagttcgac
    12301 tgcatattcc attggaagtt ctttggtgaa tggttcaaca aagcccatga cgatcatttc
    12361 agttgcttca gattcggtca ggcctcggct catcagatag tagagttgtt cttctgagat
    12421 ttttgagact ttggcttcgt gttctaaaga gacttggctg ttgtggatct cattgaatgg
    12481 gatcgtatcg gatttcgacc attcgtccat gatgatcgtg tcacattcga tatgagagat
    12541 cgaacccgca ctgtttttgg caaaggttac ttgtcctcga tagtttactt ctccgccgtc
    12601 ttttgaaatt gatttagaga cgatagagct agatgtattt ggtgcattgt ggatcatttt
    12661 tgcacccgta tcttggattt ggtttgctcc tgcaaaggcg atggagagca tggtgcctcg
    12721 tgcacctttt ccatctaagt aaacacttgg gtatttcatc gttgtttttg cacctaggtt
    12781 tccgtcgatc cattcaacgg ttgcgccttc gtatgctttt gctcgtttgg ttactaagtt
    12841 gtacacattg tctgaccagt tttggatcgt tgtgtaacgg caatacgcat cttttcttgt
    12901 aaagatttct acgatggcgg catgcaggct gttacttgaa taagtaggtg ccgtacaacc
    12961 ttcgacatag tggatgcttg ctccttcgtc aacaatgatc agcgtacgtt cgaattgccc
    13021 cgtgttttcc gcattgatcc ggaagtacgt ttgtaatgga acatcgactt tgacgccttt
    13081 tggcacgtaa ataaaggtcc cacctgacca tacggctgaa ttcagcgctg ctaatttgtt
    13141 gtcggttggc ggtacaagtt ttgaaaagta ctctttgaat aattcagggt attctttcaa
    13201 agcagagtca gtgtcagtaa agacgattcc taacttttcg aattcatctt tcatattatg
    13261 gtacacgact tctgattcat attgtgcgga agcaccggct agataagctc gttcagcttc
    13321 tggtatacca atcttttcaa atgtatcttt gattttttct ggtacgtctt cccagtcacg
    13381 agcgggtttg tcacttggtt tttggtaata tttgatggca tcgaaatcga tgtctgaaag
    13441 gtcggggccc catgtttgca ttggcatttt gttaaatgtt tctagagatt tcagacggaa
    13501 ttcaagcatc cattctggtt cgcctttgat tcttgacatc tcacggatca cttcttctgt
    13561 caagccttct cctgtactga aaaccggttc gacatcatcg tgaaacccga atttatattc
    13621 ttctaattct ggtacgccca tgttctcact cctcttcctt gtggtaatga tggaaagctg
    13681 cggtaccatc gttttccatt gcttttccta gtgctttcca ggcaagtgtc gcacatttga
    13741 tccgagcggg aaatttagct acaccaccaa gcatagcagc atcgcctaat tggtcgggat
    13801 ctttgacttc ttttccttgg acaagctgta gaaagtctac agttaaatgt tctgcttctt
    13861 ctattgattt tccgatgacg gcgtctgtca tcatcgaggc acttgccgta ctgatggagc
    13921 agccactgcc gtcaaaggcg atatttttga tgattccgtc ttttacatcg acttgcaatt
    13981 cgatcacatc tccacatgtg gggttgttca attcgatctt gcttgtcgag tcagtcaagc
    14041 ttccacgatg atgcggatgg gaagaatgat ccaagatcac ttgacggtat aaattgtcta
    14101 atttagatag tcccatgttg gaaaaactcc tttgttgcca tgattgcttc aactaaacgg
    14161 tcggcgtctt gcgttgtgtt gtagaaataa aagctcgcgc gagcagtcgc tgatacttca
    14221 aggtacttca atagcggttg cgcacaatga tgacctgctc tgacggctac cccttccatg
    14281 tctaaagctg tcgcgacatc atggggatgt aacccatcca aattgaatgc aacgactcct
    14341 gtccgaaaat tcgggtcttg tggaccataa acagtcaatc catcaattgc ttgtaatttt
    14401 ggcaacacat aagcggctag ttcttcttca tatcgatgga tattgtccat accgagtttt
    14461 tgcaaataat cgattgcatg gcctaatgcg atagcgccgg cgatatttgg tgtccctgct
    14521 tcgaatttcc aaggtagttc tttccatgta ctgtcgtata attcgacaaa atcgatcatt
    14581 tcgccaccaa attcaacagg ttccatttct tctaaccatt ttcgtttacc atataaaaca
    14641 ccaatacctg ttggtccgca cattttgtgt ccgctgaaag caaagaaatc acagtctagt
    14701 gcttggacat caatggccat gtgcggggca gattgagcac catctactac gatgaccccg
    14761 ccgttttcat ggacaagttc agctaattct tgaacaggat tgaagacacc taagacattg
    14821 gatacatgag caatggagac gattttggtt ttgtccgtaa tctttttcgc tgcatcctcc
    14881 atatccagga agccttcttc tgttagttcg atatatttca agacagcacc tgttcgtttt
    14941 gccaactgct gccacgggat aacattagaa tgatgttcca tgtaagagag cactatctcg
    15001 tctcctgctt tgatatagcg gtcgccgaag gttctggcta cccaattcaa gcttgtcgtc
    15061 gtaccacgag taaacagcac ttctgctgtt tcttttgcat ggatgaacgc ccgtactttt
    15121 tctcttgctt gttcataatc atgggtcgcg cgttctgcta acgtatggac accgcgatga
    15181 acattggcgt tatcgtgttc gtaatagtac gctaatgcct ggagtacttg ttttggcttt
    15241 tgggtcgtcg ctgcattatc cagataaact aaaggttcat cattgacgtc ttgaaataag
    15301 ataggaaaat cattgcgtag ctttttagca tcgatcatcc attcaacttc ccttcgatta
    15361 cttcgactaa ttctttccga acttgttcta cagggattgc tgttaagaca gaaccgagga
    15421 atcctcgaat cactaagcgc tctgcttctt ctttatgcaa tcctctactc atcagatagt
    15481 acatttcttc tggatcaact cgtcctacac tggcagcatg tccagcagtt acttcgtttt
    15541 catcgatcaa aagaatagga ttcgcatcac cacgtgcttt atcagaaagc atcaagacac
    15601 gactttcttg ttgggcatct gcaccttttg cccctttcaa gatgtggccg ataccattaa
    15661 aggtcaatgt tcctttttct cggatcactc cgtgttgcaa aatatgcccg atcgtatgag
    15721 gggctttatt ggttactcgt gtatcgattc cttggatttg tctgcccgag ctgattgcca
    15781 cgattttgac ttctgcgtgt gcaccttctc ctgctaaatc tgagtcaaag tcagcgatca
    15841 catgaccgtc attcatgaca ccaattgccc agtcgacaga agcatctcgt aaaatgtgcc
    15901 cacggcgatt catataagaa gtaatatttt ctcctaattg atctacggct gaatatttga
    15961 tttttgaacc agctttagcg atgacttcca cgatgatatt acctgatgat tttgctactt
    16021 gttctttggt tgtctggaaa cgttccagat aagaaaattc actatgttca tctgccacga
    16081 tcaacacatg cttgaagaag tgctcatcgg atgcgccatc ttgaatgaat aaggactcga
    16141 gtggttcatc gatcacgaca tttttaggca catacaggaa aataccgctg ttcataaaag
    16201 ctacatggag tgcagtcaat tggtcttcgt tcatgtttac tgcttttttc atataatatt
    16261 cttggactag ttctggatat tcgatcattg cagtgaacaa gtcggtaaaa atgactcctt
    16321 tttctgctaa ttccacaggc agttgttcaa aaatcgtcca tgaaccttgt tggacaagca
    16381 caggattgtc tttcattgca tcaaatgccg gaatcgtgcc tgtttcactg atggtttgtg
    16441 tttctttcac atcaaataac gaccagcgat ggaatttcac ccgatcgata tgcggcaatg
    16501 gcagttcatc tgctttcgct agtgcgtctt gacggaaggt tctcatccaa tcaggttcgc
    16561 ctttacttaa agaaaaatca tttaccgcgt caagataatc gagccagttt ttttctttca
    16621 ttcttgctcc cccttacgct tcttcttctt tatagtcgat tcctaattct ttactgatac
    16681 cagcgtagcc ttctgcttcc agacgtttag ctaggtcagc attccctgtc atgactactc
    16741 ggccttccat catgatgtga acgacatcag gtgtgatata gttcaataat cgttgatagt
    16801 gggtgatgat caatgcaccg aaattgtctc cgcgcatttc atttactcct ttagcaacga
    16861 ctttcaaagc atcgatatcc agacctgaat cgatttcgtc taaaattgca aatgtaggtt
    16921 ctaacatcaa caattgcagg atctcattcc gtttcttttc tccgccagaa aaaccttcgt
    16981 tcagataacg ttcagccatt tcttctggca tatttagtaa agccattttt tcatctaact
    17041 ttttcaaaaa tgccataaca gaaattttgt cgttttcatc acgtttcgca ttgatcgctg
    17101 cacgcatgaa ttccgcattc gtgatacctg gtatctcact tggatattgc atagctaaaa
    17161 ataagccaag tcgcgcacgt tcatctactt ccaagtctaa aacatttttc ccgtcaaaca
    17221 aaatttcgcc ttctgttact tcatagtttg gattgcccat gatagcggca gataaggtag
    17281 attttcctgt gccgttaggt cccatgatgg catggatttc tccggttttc attgttaggt
    17341 ttacgccttt aaggatttct ttttcctcga tcgacacatg tagatttttt atttctaaga
    17401 cagacatgca ttataccccc aaattctctt tcgttctcac tcattttaga ctaattgaga
    17461 atgaagcgca atgaccttcc ttactaaaat caaatatctt ttatttatta ttaaacaatt
    17521 ttgatttcta aattagaata ggtataaaaa agatgagaaa taagccatta cagacttatt
    17581 tctcatcttt tttgttccat accttatttt gcatcagcct ttactggttt aacagagccg
    17641 ccccatttgt ctgtgatcca ttcttggact tctttgcggt gaagcacttc aatcagtttt
    17701 ttgattttgt cactgtcttc atcaccttta cgagtcgcaa taatattcac gtaaggagag
    17761 ttgtcctttt caagcaatac ggcatcttct aatggattca accctgcgcc gtaagcgaag
    17821 tttgcgttga ttgcaactag gtcaccttca tcattttggt acgtagaagc taaaagtgat
    17881 gggtcgatcg tatggttgaa cttcaagttc ttagggtttt cttcaatatc atcgaatgtt
    17941 gctgtttcca gatctactcc atctttgact ttgactaagc cagcatcttg tagaattgtg
    18001 atgatgcgtc cccagtctga ttcagaattt gaagtaatga ttgttgcacc atcttttaat
    18061 tcggaaacat ctttgacttt tttagagtac aagcccattg gttcgatgtg gacagcaccg
    18121 gcattgacaa agtcatatcc tttttctttg atttctttgt tcaaataagg aatatgctgg
    18181 aagtaattgg catcaatgtc gccttcttcc aaagattggt tcggtaatac atagtcatcg
    18241 aatttgacga tttcaagatc gattccttca tctttcaata atggtttcac atgttccaaa
    18301 atctctgcgt gcggtgtcgg tgaagcgccg actttcaatg tcgtgtcgtc tgctttattt
    18361 gctgaatctt tgctgtcgct gttgttaccg catgctgcta atcctacagt cagcaaaagc
    18421 gctgctgcaa atccaaaaat tttctttttc atatcctaca tccccctata tcctattatc
    18481 ttttgtctgt tttcttagtt aagaaatcac cgattccttg aacgataaat acgattagta
    18541 aaataattaa agtcgcaacg aatgtcactg ttagattacc acgctggtag ccttcctgcc
    18601 aagcaagacc tccaagtcca cctgcgccga tcgcgccggc catcgcagta aatccgatca
    18661 tcgagatcgt tgtaactgtt aatccagaaa tcaatgcggg aatactttca ggtatcaaga
    18721 ccttccagat gatttcccag taacttgctc ccattgcatc tgctgcttcc agtacaccag
    18781 ggctgacttc acgaaaagca atctctacta gacgggcata aaatggtgct gcggataaaa
    18841 caagagctgg aatggctgct tgcgcaccta gcatagtgcc tacgattgct ttagtaaatg
    18901 gaatgatcaa aaccatcagg atcataaatg gcgttgaccg gaaaatatta ctgatgatcg
    18961 atacgattcc ataaatgatt cgagcatacg gtttgttttt gcgtccaata gagtaaagga
    19021 tcaatcccaa aactaatccg atgatcgtca ctaagaccat tgagattaat gtcatatata
    19081 gtgtatcaag gatagcctga ttcatcgttt ccgggttgat ttgtttaaaa tctagatatg
    19141 tttctgaaaa gcttttatcc acgatggatc acctcaattc ctactccttg ttctttgatg
    19201 aacacttctg cttgatctaa ttctttggtt tcaccagtca tcaagacagt caatgaacca
    19261 aaggaacctt ctttcacttg tttgatcttt ccatacacaa cgttgacatc gatgttatag
    19321 cgtcgaatcg cttgggaaat gactggctcg ttggcatttc tttcgctaaa ggtcaaagtt
    19381 gccaaacggc cgcttggatt ttctttgatg agttcagcta atagttctgt cgaatcagct
    19441 tctggttcga tgtcttgttg tacaaagcgt ttggttactt cttttttcgg ttgtctgaag
    19501 acagtcaata cgtctccttc ttctacgact ttccccaact ccatcacagc gactttgttg
    19561 cagattttgc ggatcacatt catttcatgt gtgatcaaga cgatggtcaa attcaatttc
    19621 ttattgatcg ctaacaataa gtctaatact tcttctgttg tttgcgggtc caatgcgcta
    19681 gtagcctcat cacaaagcag gatctcagga tcatttgcca atgctcgtgc gataccgacg
    19741 cgttgtttct gtccgccgga aagttgtgaa ggatatgctt gtccgcgtcc ttctaacccg
    19801 actaaacgca acagttcttc tgcccgttct ttacgtttgc tctttggtac gccagctaat
    19861 tccagcggca gctggatatt ttcaagtaca gttcttgacc ataacaggtt gaaatgctgg
    19921 aagatcatac cgattttctt tcggaatgta cgtaattctt tgttttttaa ttttgtaata
    19981 tcttgatcgt ttacgatcac ttcgccgctc gtgggaagct caagtccatt caggagacgg
    20041 actaatgtac tttttcctgc gccagaatag ccgacgattc cataaatatc ccctttttca
    20101 acgtttagtg aaacgtcatt gacggcttgg atgtttccgt ttttcccatt gaatgtcttt
    20161 ttgacattcg ttagttggat taatgacatg ccattcacat ctttctctta taatttttca
    20221 aacaaaaaag ccttcgccct cttgccttaa gcaaaaggac gaaagcttga acttccgtgt
    20281 taccaccttg atttaccgtt acttcgcaat aacagcctct tccagtactt ggacttagct
    20341 tctttccgta tactgtcgcg ctgtaacggg cactcccgta gtaagtttgc ttacgctcgc
    20401 ttactctgct ctaagaccat cttccatctc attttcgtta cccattttca gcaaacaggg
    20461 ctctcttcaa acgtccgtga catgtactct tcttttcaaa gctttctcgt ttcatatagg
    20521 attgcttatg attatagcaa ctggaagaat cagtgtcaac ttttttcaag tgattttctg
    20581 attttataat tcgtcaaatt cttttggatc aacatctttg aaacttaaga tccacgcatt
    20641 catttcatct gaatcattca agatattgat atcttcaccg attttatcat taacagaaga
    20701 aactgtaccc gttagcgggc tggcaaattc attgaccgct ttttccgctt caacttcgat
    20761 cagaggttca tcttttttta gcgattgtcc tgcttttggc agattggcaa acgtgatgtc
    20821 tccaagttct tcttgcgctt catttgtcaa accaacacag tattcttttc cattaaataa
    20881 gatccaaagg ttgtcctttt tcttcaaatg cttgcctgcc attttatatc agttctcctt
    20941 cataaatttt ttcattgaat ccaattgcaa caagctggtc ctctcgtaag atcagtggtc
    21001 gcttgatcag cataccatct gtcgataaga cttggctcgc ttttgaagcc gtaaactcgc
    21061 ctacttgatc tttcagtcca agttcccgat atttcatccc gcttgtgttg aacaggcgac
    21121 ggattggtac ttgactcgtt tctagccaag tctcaatcgt tgaggccttc ggtacttctt
    21181 tgatcatatc aacggtttga taactaacgc catgctggtc taaccacgct ttggcttttt
    21241 tgcatgttga acatttcggg taccagtaaa aggtgtacaa ttttcttacc tccttgaaga
    21301 tcttgcaggt gcttcatttt ggtatctcat cgataatatc aacccgatac cgatcatgtt
    21361 ccctaaaatc gaggatcctc cctgactaat gaaaggcaat gggatccctg ttaaaggaag
    21421 taatccgata tttgctccaa tattctcaaa gacatggaac agcagcatca tgatcaaacc
    21481 gcttgcgata taggcgtaaa attcattatt cgtatcgaaa cacacccgaa tcatacgata
    21541 gattaaaata aaatacaaga aaatgacgaa tgcaccaccg ataaagccga agttttcacc
    21601 gataacggta aaaatcatat cggactcacg aacaggcaca tagatattgc ttacgttgaa
    21661 tcctttacca aacaagccac cggtaccaat tgccaaaagt ccttgggccg gctgataact
    21721 cattcctgac gtatcatgga aagggtccag ccatgaatca atacgtgcaa actgataaga
    21781 tttgaatcca actttataaa gcaagtctct tccgccttca gtcgtaacca agaagatcgt
    21841 tcctgctcca acgactactg ccaagattac tacaggtgcg atgatgcgcc aagagattcc
    21901 agacatcagg aaaatcccgc caaagatcgc aagaaagaca agcatcgttc caaagtcatc
    21961 ttgggccatg atcaatgcta aaaccggtat tgtcacgatc aagagcttcc caatcagcca
    22021 aaagtccgat ttcatcgtcc gttcttttac ttgcgtatta tgtttagtta cgatcagtgc
    22081 catcatcaag atgtacgcaa tcttcatcaa ctctgctggc tggaaagtaa acgcaccgaa
    22141 tcgaaaccag tttttagacc ctgttgaagc agctaaattc tgatcataga atttgagcaa
    22201 gagtcccatt accactaacc ccaaaccata aaggtaagga gtcagtttcc agatccattt
    22261 ggaattcaaa tgcatgatga caacgattgc tgccgctcca actaaatacc agacaacttg
    22321 catccctacg cctttcaaga ctgctggatt gttcggatca tggctaagtg ctacatataa
    22381 tgagagcaga ccaatcaaac ataacagaaa gactggtaaa atcacgccat aatcaatacg
    22441 attatcgttc gaagctttta attttttttc catgtttcat cccttttctt aaaaaccata
    22501 ctgctgatta ttatagcggt ccagttagat aatggaaagt ctttccatag acatttggga
    22561 aaaattaact ttccgtttgt gcagttgctt gagcaaatgc agtacaaaag cctactgctt
    22621 atctttagtg tatcatagaa ctttttttga tacatgcaat tatctaccag ctgagattct
    22681 cctcgctgtg agaagtttct gtgctttcat tgtatcgaag gatctcttcg gcaatctcta
    22741 gcagctgatc agaaaccaga ttggttcgtt ggatgaaata aaaatatcga tggaaattca
    22801 acggagtcat tggcacattt tctggaacag agcgcttaga caaaatcgag cgaccgattc
    22861 cttccttcag caacgcaaca attacatcgt tacttttcac gatcatcttc ttatcttgga
    22921 tattcatctc ttcaaaataa cgcttcgtgt aatgaaaaac accagagttt gcttctctta
    22981 caagccacaa tttgcttttt gggtccccag cgatgactag ctggtcttcc atcaaagagt
    23041 atctttgtac gccggaagtc tctaatggct tttcgataaa accaaaatcg gattcatgtt
    23101 tcgctacttg ttctaatgat tcatgagaat tcgtgatttc gatctcaaaa tgcactttag
    23161 gaaacctttt gatcagatgt ttcatcaact gaggcaaaag atggacagca aaggtgtggg
    23221 aagcaacgat ccgacatact tcttcttcat tttgttcatt gagcaatttt tgctgagttt
    23281 cttcccattc ttctaacaaa accagtgtcc gttcatataa taagtcggct tgcttagttg
    23341 gaagcatctc ttttcttccg ttacgttgaa aaagatcgat attcaattcc cgctccaact
    23401 gtttgatttg attcgagact gctggttgag ataaaaacag tacttctgct gctctggaaa
    23461 aatttcttgt ttcatatact gctcgaaaag tcgttaataa cttaaacatg gcaccacttc
    23521 cataactttt tatgataatt actataaaaa ctatttgatt taaatataca aaaaaccatc
    23581 tataatagaa atgtacaaca aaacagttgc tgatccaact agtaacttag atgaagacaa
    23641 tcagctgtct gcttgctcgt aatcatacat tcctattcat tttacaatgt attcgttcat
    23701 cttggtacta aaatctatta aataaaaagg agaatattat atatgaagaa ctttttgaaa
    23761 attattccga tcccgatctg cgggttgatc cttgggttag cttcccttgg aaatctgttt
    23821 aaagactatc accatgttgc tttaggcaat ctaactggcg gtatctctat gattcttatg
    23881 atattcattt ttgttaaatt gtttatctta ttcgaacaca cgaaacaaac gttgcatgat
    23941 ccaatcatcg cctccgtttc accaactttt acgatgtcac tcatggttat ttgtacttat
    24001 tttgtttcat atgaaagtat tgcaccaatt gtcaaattca tttggctgtg cgctgttatc
    24061 ttccaagtga tccttgtctt ttatttcaat tatcaccatg ttatcaaagc tgatctttca
    24121 attgaagcaa tttatccaag ctggtttatc atttacgttg gatttggggt catcactgta
    24181 actgccggga acttcttccc acttattgga aaaattttct tttggatttc attgatctgc
    24241 tatgcgttct tattgccgat catcatcaaa cgtgtctttt tcgtaagaaa tatggctcat
    24301 ccgacacgtc cgctgattac gatcgttgca gcacctggtt ctctttgcct aacaggttat
    24361 cttaaaaact ttgctgaacc taatttttat cttgtcgtag cattgttcgc tttatctcaa
    24421 gtattgtatt tcgttgtgct gtctatgctt ccacgtttgt tcaagcttcg tttttatcca
    24481 agctatgcag cctttacatt cccgcttgtt atctctgcaa cagctatatt tactactgtt
    24541 cattacttca acagtttagg tatctatagt agcgtattgg atttcttaaa agttgcggaa
    24601 tgtctgtttg caagtgtagt tgtcttctac gttcttgctc attacgtacg tttcttaatt
    24661 aaagaacata gcaaacatgg aaaatttgtt tctaaaaaaa tcgcttaata atcgattcaa
    24721 taggttgtga aaaagctgtt ctgcatcaag taataagaac ggccaaacaa aaacagctgt
    24781 tcatgttttt gtactggttg ggcttattac cgcagatgca agcttttgaa caccgtttac
    24841 caagaggtcg taaaagaagt ggtcagcttc aagaaataag aaggaattta cgaaaattgc
    24901 ttctcaaatt tttgtgaaat ttcggcttat ttccgtagaa gctacttctg gaacaccgtt
    24961 tattcgaaac aagaggtcgt acaagacttt tgtcacgacc tcttgttctt ttgtcaaaat
    25021 actggtttag tgctactatg ttcgagtatg cttttagtat ttattgacga aaggaaccga
    25081 tcaaatgaaa tcattgtcac atccaataaa atctgtaaag gattcagcgg tccgcgaaat
    25141 cttacccggt ttactgcttt cttttgccat cgctgccttc agcaggcttc ttgctattta
    25201 tctgccacag ttaggtggag cgactattgc tattttattg ggtattttat taggaaatac
    25261 tttttttaaa cagcctgttc tagcaatcgg cacaaaattt gctgaaagca aactattaga
    25321 attctctgtt tttttactag gtgcaactgt cacagctcaa acgattgctc aaattggtgt
    25381 aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact atcatcggtg cttacttgat
    25441 tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg atggctggag gaaacgctgt
    25501 ttgtggttct tctgctattg cttcaatcgc cccttccatc catgcgaaag aggaagaaaa
    25561 aggacagatc atcacactag tcaatctact gggtactgtg atgatgttga ctctcccttt
    25621 tcttggatta cagttgtttg gtggaaatct cattgaaaaa agtgcacttt tgggtggtac
    25681 actccaatct gttggtcaag tagtcgctgg ggcaagctta cttgacaatt ctgttgtcga
    25741 attcgccatg ctatttaaga ttctacgtat tatgatgctc gttgttgttg tctatctgtt
    25801 tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa acgccaactg atacgcagaa
    25861 aaaacgaaaa ttaccgcttc cttggtatgt attagggttt gtgatctttt gtttggtcaa
    25921 cagcttgttt tctttacctg tagttattga ccaatcggca cattttatca gcagctggtt
    25981 tgagatcact gctttagcgg caattggtct gcgtttagac tttgcaaaat tcatgaaaga
    26041 aggtacacgc ttcttatctt atggattagc tgtcgggctt ctccaaacag tgatggcttt
    26101 actatttatt tggctgatca aagtttagaa tgaacatgaa aaaacagttg tgattctcgc
    26161 atggaacaat gtccgaatca caactgtttt taattttgca gatatccttc taacaacaac
    26221 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
    26281 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
    26341 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
    26401 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
    26461 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
    26521 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
    26581 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
    26641 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
    26701 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
    26761 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
    26821 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
    26881 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
    26941 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
    27001 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
    27061 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
    27121 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
    27181 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
    27241 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
    27301 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
    27361 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
    27421 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
    27481 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
    27541 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
    27601 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
    27661 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
    27721 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
    27781 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
    27841 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
    27901 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
    27961 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
    28021 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
    28081 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
    28141 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
    28201 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
    28261 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
    28321 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
    28381 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
    28441 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
    28501 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
    28561 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
    28621 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
    28681 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
    28741 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
    28801 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
    28861 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
    28921 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
    28981 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
    29041 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
    29101 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
    29161 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
    29221 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
    29281 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
    29341 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
    29401 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
    29461 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
    29521 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
    29581 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
    29641 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
    29701 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
    29761 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
    29821 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
    29881 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
    29941 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
    30001 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
    30061 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
    30121 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
    30181 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
    30241 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
    30301 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
    30361 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
    30421 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
    30481 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
    30541 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
    30601 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
    30661 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
    30721 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
    30781 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
    30841 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
    30901 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
    30961 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
    31021 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
    31081 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
    31141 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
    31201 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
    31261 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
    31321 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
    31381 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
    31441 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
    31501 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
    31561 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
    31621 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
    31681 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
    31741 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
    31801 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
    31861 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
    31921 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
    31981 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
    32041 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
    32101 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
    32161 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
    32221 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
    32281 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
    32341 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
    32401 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
    32461 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
    32521 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
    32581 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
    32641 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
    32701 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
    32761 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
    32821 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
    32881 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
    32941 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
    33001 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
    33061 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
    33121 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
    33181 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
    33241 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
    33301 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
    33361 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
    33421 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
    33481 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
    33541 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
    33601 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
    33661 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
    33721 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
    33781 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
    33841 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
    33901 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
    33961 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
    34021 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
    34081 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
    34141 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
    34201 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
    34261 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
    34321 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
    34381 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
    34441 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
    34501 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
    34561 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
    34621 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
    34681 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
    34741 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
    34801 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
    34861 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
    34921 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
    34981 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
    35041 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
    35101 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
    35161 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
    35221 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
    35281 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
    35341 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
    35401 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
    35461 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
    35521 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
    35581 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
    35641 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
    35701 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
    35761 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
    35821 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
    35881 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
    35941 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
    36001 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
    36061 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
    36121 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
    36181 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    36241 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    36301 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    36361 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    36421 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    36481 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    36541 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    36601 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    36661 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    36721 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    36781 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    36841 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    36901 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    36961 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    37021 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    37081 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    37141 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    37201 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    37261 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    37321 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    37381 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    37441 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    37501 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    37561 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    37621 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    37681 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    37741 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    37801 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    37861 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    37921 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    37981 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    38041 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    38101 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    38161 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    38221 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    38281 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    38341 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    38401 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    38461 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    38521 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    38581 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    38641 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    38701 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    38761 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    38821 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    38881 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    38941 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    39001 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    39061 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    39121 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    39181 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    39241 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    39301 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    39361 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    39421 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    39481 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    39541 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    39601 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    39661 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    39721 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    39781 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    39841 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    39901 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    39961 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    40021 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    40081 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    40141 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    40201 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    40261 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    40321 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    40381 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    40441 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    40501 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    40561 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    40621 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    40681 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    40741 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    40801 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    40861 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    40921 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    40981 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    41041 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    41101 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    41161 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    41221 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    41281 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    41341 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    41401 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    41461 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    41521 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    41581 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    41641 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    41701 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    41761 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    41821 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    41881 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    41941 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    42001 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    42061 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    42121 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    42181 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    42241 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    42301 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    42361 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    42421 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    42481 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    42541 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    42601 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    42661 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    42721 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    42781 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    42841 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    42901 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    42961 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    43021 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    43081 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    43141 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    43201 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    43261 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    43321 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    43381 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    43441 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    43501 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    43561 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    43621 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    43681 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    43741 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    43801 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    43861 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    43921 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    43981 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    44041 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    44101 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    44161 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    44221 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    44281 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    44341 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    44401 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    44461 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    44521 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    44581 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    44641 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    44701 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    44761 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    44821 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    44881 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    44941 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    45001 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    45061 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    45121 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    45181 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    45241 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    45301 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    45361 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    45421 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    45481 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    45541 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    45601 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    45661 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    45721 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    45781 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    45841 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    45901 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    45961 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    46021 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    46081 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    46141 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    46201 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    46261 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    46321 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    46381 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    46441 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    46501 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    46561 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    46621 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    46681 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    46741 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    46801 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    46861 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    46921 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    46981 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    47041 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    47101 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    47161 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    47221 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    47281 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    47341 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    47401 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    47461 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    47521 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    47581 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    47641 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    47701 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    47761 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    47821 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    47881 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    47941 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    48001 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    48061 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    48121 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    48181 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    48241 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    48301 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    48361 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    48421 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    48481 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    48541 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    48601 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    48661 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    48721 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    48781 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    48841 gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct aatttatttt
    48901 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaatataact
    48961 taagttgttg ataataaaga gatttattaa cgtaaaaaga ataagttttt ttaaaataac
    49021 gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc tcttctttta ttattttgtg
    49081 ctttttattt tatcaaatca ctttgttttt ttataaaatt tctgcgccta gtgtggactc
    49141 aaaatgtctc aatgcccatt catgtccaac gggatcgaaa cttgccacgg aatctttgaa
    49201 aatatggagt ttgtatccta gattatacgc atcgactgct gtatgcaaca cacagatatc
    49261 tgtacatacg ccggtcaaat aaatatctgt gatctggcgt tctcgcaaac ggatgtctag
    49321 atctgttcca ctaaaagcgg aataatgccg tttgtctatc caataaacat tttcctcttg
    49381 ctcatagtct tggtataaac tttttaaaga gccgtacaat tcccgtccac ccgttcctat
    49441 cacattatgc ggaggaaata agcggttctc cggatgaaag gaatcttttg gatcatgcgc
    49501 atcaatggca aaaacgacaa aatccttttg atcaataaac ttctttgtat gagcagtcag
    49561 ctttttttca attacttgtc ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa
    49621 atcatatgtg tagtcaatcg agatcaatgc gttcatctta gtcctcctta tacgagatgt
    49681 ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca
    49741 aagctttgtg tcgccgagtg atctgctgtg tcgctcattg cacgtacgat caaaaatggg
    49801 atattgaact gacgagctgt ttgtccaaca gcggctcctt ccatttcgca agctaatgct
    49861 tcagggaaat tcgttaagat ttctttgatt ttatctggcg agtcgacaaa tgtatcacct
    49921 gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca
    49981 ctgcgcaaat atgtgcttgc ttcataatat agaggcattc ctggtaattg tcctgggttg
    50041 tagccaaatc ctgttgcatc tgcatcaaaa taagctactt tgtctgatat aacgatgtca
    50101 cctacttgta agccttcacc gattccgcca gctgaacctg tattgatcac catgttcacg
    50161 ccgtattgtt ggatcaacag acttgtggta atagatgcta agacttttcc tataccggaa
    50221 cgtacgacga tcacttcgtg gttacctaat gaacctgaaa taaataaagc gcctgcgcgt
    50281 tcccatgata atggttcgct taggttctct ctcaaaattt ttacttcttc ttccattgcg
    50341 ccgataatac cgattttcat ctttttaatt ccttctttct atataaatgc gattgctaaa
    50401 aaaaccacac ataacattag gataacaata ataagagatt tcatcaaaaa agagttccat
    50461 ttggtcgtct tttcccgttc gctgatcctt gttttcgtga ttggtttatt ctttttgctt
    50521 tctttacgat aaaagctggc aatctttttt tcttcttgct gataagctgt ttctgctttt
    50581 cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc
    50641 gtaataagcg gtcctttggc cataagccga tccctctact ttcctttggt caatagttcc
    50701 cagtattgaa tcgcataaat cgtctttgca tcacaaatca actgatcttt catcgcttgt
    50761 tgcgcctctt caagagttag atgatacaac tccagtactt cgtcttcatc ttgtgctaaa
    50821 ggattctcga ccttctctac cccttgtgca tgataaatat gaaggacttc atttgcaaaa
    50881 cctggtgaaa gatacatcga agtaagatgg ctcagcgact tcgcacgata gccagtttct
    50941 tcttctaatt ctctagctgc tgtcatttcg ggattttgtc cttctcctgg atcgattttt
    51001 ccagctggaa tctccaaaat cactttttct aaaggttttc gaaattgttt gacaagaagc
    51061 agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc caggatgaaa taccagttct
    51121 ctcttcgaag ttcctccatc tggcaaacga acttcgtcta cagcaacatc aataattttt
    51181 ccgctataga tttctttgcg actgattgtt ttttcttcaa attgctcatt gttcagcata
    51241 tcttctcctg ctttctttgt aatcataact gctttttttt catttttcaa tttttctcaa
    51301 aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat agaaaatcct
    51361 tctttagtcc gatactcttt ctagtagtcc gtatgctaaa ataagtatgt aatcgaataa
    51421 cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga taaaacgaaa
    51481 ttggccgtgg cttctagcat tggtcttgct atttctcttt gtccgaaaca atagtttttc
    51541 ttttgttcta ggacttttat tgataggtgt agttttagtt ttgtggggac tctttggttc
    51601 gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg actgacgaac ttgaaactca
    51661 ctatgaaaaa agcggtatga cagcgaatga aatttcattt tttcgacaaa caatgaatca
    51721 aacaaaaaat gagatcaatc aattgcaaat gaatatgcag cagacagcca aacttaaagc
    51781 aatcgatctc cgccatgatc cagtcaaagc agcgaaagct ttattcaaag aattggtgaa
    51841 agaaccaaac cgactgcatg aagcaagtca gtttctttat acgcatctgc cgaatctagt
    51901 tgatttgaca aataagtata atgagatcaa tgaccatgag atcaaaaaca aacagaccta
    51961 tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg tcagctttaa tcgcacaaga
    52021 ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac gtagagatat ctgttgcgaa
    52081 acagagctta aagcgtgata ataaatatga accagaacaa aaggattaac tcttttgttc
    52141 ataaaagaag actcggaaca ttcagatgat gtctggctgt ttcgagtact ttttctaaag
    52201 tagagacatt catgtaagaa tcgagaacag attcaacaag gaggaatttt ttatggatca
    52261 taaaccgact gaaacaaaag atgttacacc agttaacgat acacttgaag atttattgaa
    52321 caacccgttt tcaactccaa cagatacgct gaccacttca caacaagcgg agattgatca
    52381 gctccaagag caacagacag ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga
    52441 acaagctaaa cagctagcag caaaaatcga tgctaatgat gcacagtctg tcatcagcta
    52501 cggatcggct gcccaagcaa aattaagtga attctcacaa tcgatgttga atcatgtgca
    52561 agcacaagat attggtcctg taggagattc cttaactgaa ctgatgtatc gtctccaaga
    52621 agccaatcct gacgaactgc gtgccggaga agggaacatc ttccagcgtg tcttcgggaa
    52681 ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa aagattggtg cacaaattga
    52741 caagatttca gtgaaattag ataaagaaaa agacggtctg ctaaaagata atctgatgtt
    52801 agaacagctt taccagaaaa acaaagacta ctttgatgca ctgaatattt atatcgctgc
    52861 tggagaattg aaaatggaag aacttcaaac aacgatcatt ccagaagcga tgaaaagagc
    52921 agaagaaact ggcgatcaga tggatgttca gattgccaat gattacacgc aattcctaga
    52981 tcgtctggat aaacgtacgc atgatcttcg cttagctaga cagatcacga tccagcaagc
    53041 accacaaatc cgtttgatcc aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc
    53101 tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg
    53161 tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa acaacaaacg acttattgaa
    53221 gaaaaattca gaaatgctga aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg
    53281 aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga
    53341 gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg
    53401 acacatggaa gaagatctga aacaaaaact gttggattta acccaataga tcacctttcg
    53461 cttgttacta aaacaaacgc ccaacaacag tttattacaa ctgttgatgg gcgtttttct
    53521 tatctttctt ctaacttctc cattggagtc tatttctcat tcatcttgct gtgtccatag
    53581 ccatagccaa aataaatgat cagtccaata accattacga taccgaacac gatccatgtc
    53641 acagtttgca gacgaagcat caatacaata caagtcaaaa tggagacgat tggcaatagc
    53701 ggaacgaatg gcactttgaa ttctccagct tttggtttgc caaacatttt tctcaacttc
    53761 agtaagccta gactaacaag catcaaatag gcgagcgcca tgatattcgt tagttccgct
    53821 aatacattca atgggaaaaa tccggcaaag aatacagctg ccacaccagc ggcataagtc
    53881 gcttttttcg gtgtacgatg cttttgatcg atttctgtca taaacttagg aagtaagcca
    53941 tccttgctga cagcaaacag taaacgagca agtgaataca tcatcgagat cgttaccgtc
    54001 agtagcgtta aaattgcccc tacagcgatc accgcgccca ctgttccatg tcctacatac
    54061 ctcattgcaa aagccactgg gtcattgact cctagttcag tatacggaac gattcctgtc
    54121 aagatcagcg tcacgatgat gtaaaggaca gtagcaatca gtatcgaacc aatgattcct
    54181 cttggcacat ctttttgcgg gtttttgact tcctcggctg ccattgcaac ggcatcaaat
    54241 cccaagaaag caaaaaacac aagagctgca ccatctagca caccggaaaa accaaaaggc
    54301 atgaatggct gccagttatc aggtttaacg aaaaatattc ctacaatgat aaacaacgcg
    54361 atgataccaa atttgacata taccatggca ttattcaaac gtaatgcttt cttggcttca
    54421 agcgacacga tgtaagtgac gaatatcact acgagcaccg caatcaagtc aatgtatgta
    54481 ccattttccg gattgtaccc gccagttaat gcttgtggaa gttcggcccc taaacttttc
    54541 aaaaaacctt gcatatagcc agaccatccg gaagcaacag aggaaaccgc tagtaaaaat
    54601 tccccgatca acaaccaccc tgtcagccag gcagcaaatt caccaaatac aacatacaga
    54661 taggcatatg gcccaccaat cactggcact cgcgaagcaa attctgcgaa acttagtcca
    54721 gacaaaatga caacgattgc agctaagaca aatgaaagtg acagtgctgg accagcattt
    54781 tgattggccg caacccctgt caccacaaat attcccgtac cgatgatcgc accaattcca
    54841 agcatgatca aatcagacgt ttttagttct tttttcatct cactcgtatg attgagattg
    54901 atctctttct tacgaaacaa atccattgaa gttcctcccc attttaggtt ggaaaacagc
    54961 gattaaactg ttttcatata ccctaaaagg ataccaccta aaatgactaa aaggcaacca
    55021 acaataacat aaatgagctc ttttttcgtt tttctttcgc caaggatgaa aatcccacct
    55081 aaagtagaga taatgatccc catttgtgaa agtgagaagc caacagctaa accaagtgat
    55141 ttgactgtta gaagcatgca gatgtttcct aagccccata ataatccaca gatcatgttt
    55201 ttccacacaa actgatcgac tttaacttta cggaaagcaa agaagcttgc gcctaagatc
    55261 attccgatac tttgaggtaa gataattgac atcgcatcca aattcgccca gttgacgatg
    55321 atggtatata caccataacc aatcgtagag aagatcaatg ctctaaaacc cttaccaaaa
    55381 tcaagcattt tattatctgt atctattttt ccttcgtcat cttgtcgggc agtcaaatac
    55441 gcaccgctta caagaagagc taaagcaata ataccgtata cataatcttt cgtttgtgtc
    55501 cattcatgga agaaaacggc tcccgcaatc gtattcaaaa ttaattgaaa accagtagac
    55561 aatggtagcc ctacagaaac acccatgtac ttcattccat ggaactgtcc attttgtcca
    55621 acactccaag ctaagccgga taaaaatccg atcaagaaaa tccaaggggt gattacagga
    55681 ctaacaacga aaaagacaac taaagaaaac agaaatgcac cgatcgtcat tcctagtgtt
    55741 tgttgattgg catcgccacc aattttacca cttactaaac caatactacc ccatgccaac
    55801 atagggacta atgctattaa aatttccata accaatctcc ttttatttca catgataaga
    55861 aacttatcag cgaaaacgtt aacaacacaa gcactttttt tcgtttctaa cgattttcta
    55921 acgtttttca ttataaaaat ttaagattgg gaaaaataaa gtcattgttg tcccttttcc
    55981 ttcagttgat tcagccgtca aatggatacc taatttttcg gccagatttt ttgctaaata
    56041 aagtcctaat cctgttgaat gtgttttgct aagtcgacca tttctcccag taaatccctt
    56101 atcaaagatc cgtttcaagt cttccgctgg gataccgatc cctgaatctt taactgaaag
    56161 gctgactcct tgcgcttcct tttctatgct cacaatgatg tttccgtgat ccggcgtata
    56221 tttgatggca ttactaagca attggttgaa gataaaagcg atccatttag catcggtcaa
    56281 aacagtatga tcctcaccaa cgatctcgta gcgaatattt ttttggataa aataatttgc
    56341 ctgactgcgt atcacaggct gaatgattcc ttttagtcca tattcttgga tgaggtagtc
    56401 ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt tctacgtatt catcgatttt
    56461 tgataattca ttttctagta atgtatactt ttgatcgtca atatcgaact cgatcgaacg
    56521 aactagcaat ttagaagcgg aaagtggcac tttgatttca tggacccatg agtcaatata
    56581 atctttttgg tcttgttgat tactgattgc tgattgcatt acttcttggt gttcacggat
    56641 cagctgattg atatattctt ctaccagttt ttcttcttct gtcctcccac cactcaaata
    56701 attttgcaaa ggggaagttt tttgtatgtc ggctaatttt ccccaccatc ttctcttgct
    56761 caagtaacca cccagcagat aaaaaatcag aaagacgccc tcaatcaaag ctaaataagc
    56821 aattgtgctc aaatcaactt tgatgtttgg cgccagccac atcacaaaga tcgtcaatgc
    56881 aataaaaaac agccatccca agatcaatgt ccactgatct ttcaaatatt taaaaaaatt
    56941 catcttaacc gctcatcctt tcagggaacg atatatccct gtcctacttt tgtttcgata
    57001 tatccttgga tacctgcctg ttcgattttt cggcgtaacc gattgatgtt gactgtcaat
    57061 gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc gcagcaattt ttcccgactt
    57121 aagatctttc cattgtgctt catcaaaata aataatagac gatattcatt tttgctcaaa
    57181 tcaatgatct ctccgttgat ttccatactt ccgttgtcaa cattcaacgt aatgccattg
    57241 tggctcatca tttcactaga taattctgtg tagttgtaag aacggcgaag taatgcattg
    57301 atttttgcaa tcagtacatc gatttggaaa tgttttgtca caaaatcatc tgcccccatg
    57361 ttcatagcca tgatcatatc catattcgta ttcctgctgg agataaaaat gatcggtact
    57421 ttcgatactt cacgtatttt ttgacaccaa taatagccat ccaaaacggg aagattaata
    57481 tctagtaata caagctgtgg ttcttctctt tcaaagtctg agaacacttg attgaaatcg
    57541 gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct ccatgatcaa ttgtcgaatg
    57601 atctcttcgt cttcgactac catgattttt gccataaaaa atccctccat ctttcttctt
    57661 gctactacaa tatcaaagaa gcccttgtga aacaagttgg cttacctgga aaatgtcatt
    57721 ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat cgcgtttgtc tcttccaagc
    57781 agcttaaatt tattatgtta ttcttaataa ttggtctatt atctgttatt tttctttcgt
    57841 tgtttttgtc ttttaaattt tcgataacac caataaccga aaagcgttag cactagcaat
    57901 atacctagaa ggagtataag taatcgataa agatggtatt tttttgtctg ttctatcttt
    57961 gaagagactt cttctgtaaa gggaactcgt cttcctgtca ctagtaatcg gtgagtgttc
    58021 acggtgtaag gtgtacaagt gataagtgtg actagatcct gcttttctct aattgctaat
    58081 gtatttgttt ttgttggaag gacaacaatt ttctcaacga cttcataagc gagcatccga
    58141 ccatacactt caagatagaa tcggtcatct tgctccattt cttcaagatc cgtaaagagt
    58201 tttttctcag caataccgct atgggcggta atcacggaat gtgtactctc tcctccagtt
    58261 ggaaaagagg tgccttgcag gactgtcgct cctctatcta acaaaagatc attcgtttca
    58321 tcaaataaag gcaagctaac attgattttc ggaatataga tggctccgat catatgttgt
    58381 tcgtaatatt cttttcctgg attttggaca tttctaaccg cttgctcaaa aggatctttg
    58441 acttgtccca ttcctgggat tactgatgta tgagcaagcg tctgattttt cttttcatgc
    58501 actgctaatt gttgctcatg tttttcttct ttatcgcgtt caagctgctt ttgataattc
    58561 tcgatccttc tttgatccaa ataattgctg agagcatctg ctaaaaatgg atatgtaaaa
    58621 actgcagctc cggcaagaaa catcactgcc ataaataatt gtaataaaag actgatttgg
    58681 gtttgaggtc tattacctat tttctttttc attttcttca ccttcttatt taaaaaaact
    58741 gcagcaacct ttataaaacc gattgctgca gcttattttt gttgcttata cttcagactt
    58801 cattttagat ttacggtacc agctgtacgc tccaatcatc aaacttattc cgattagtaa
    58861 gaatgccaag agcccgttcc caccagtagc aggaagtgac ccgcgtttca tattcggtac
    58921 tctttctggc cctggatttt ctactcctac gatctgaatt tcttcattat agcttccata
    58981 agagatgata aattcagtaa aggctgcctc acctgttgga agtacataac cttctggcgc
    59041 catggtctct ttcatttgat aggttccata atctaaccct tgaacctcaa agtatccatt
    59101 tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc cactcaattc tatctgctcc
    59161 tgattcataa acagctaaag gcgactcccc tttataaaat attgcgtatt cagaacggtc
    59221 ttcattccac aattcgaatc ttgcatcttt aagcaattca ctgcttgatg catcatattt
    59281 ttcaaacttt cttccacctg ttgtgacttt ctctggcggc tctactcctt cttcataatc
    59341 aaattcatca tttcgtccga tttcaataac cgctgtgttg ttatggaaat catccgcttc
    59401 tagttctgtg gaaaccttca aattatacgt gatcgttaaa tctcctccac gtgcatctgc
    59461 taatctacct aaagtatcta ctttggctac tccattttct tctgtcaaaa tcgtcacgac
    59521 aaacccgttg cttactactt ctactatata atcttgtcct tttgttaaaa tcgtctcgcc
    59581 ggctcgcact tctatttcct gatcataata agttagacca actgtaggcg tatctgtgat
    59641 tttgtaattt ttgataacag cgcttccgtt ttcaaggaca gaatcgatga aataaggaat
    59701 aggtgctgtg atcgtgtaag aagccgtttt tcctctttct agatcaatat aagaaatcgt
    59761 ttcttgttct ccagcttcat taataatcgt tacttgtcta aggtcgcttt cctctacatt
    59821 catctgttta tctgcttctc tgatttcgtt tttcggatac aaatgcacat ctgtattgta
    59881 tgtgtctttc catgtagaac catcccacac gccatccacc atatcaggca tcatcactgg
    59941 catcataaca accattggag acgcgattct ggaaatatga gctggcgaat aagtttctaa
    60001 gaaaagatag actttatctc tagaagaagg tgcttcttcc gtcacttgga cggtagagaa
    60061 taccgcttct ccagcttcat tcgttgtttg tttgtcaata cttgtcagtc gatattttaa
    60121 aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc gcttcggcag aattaagacc
    60181 gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa tcgtaatata cttccgttac
    60241 gtcaaacaaa tcaaaatcga ctcctggaat attttcttca ccaaaatccg tagaaaccaa
    60301 tccgctattc ggtcgttctt ccggaacaga tgagaaacct tttttgtgta atgtaatcgt
    60361 cacttcactt ggtttttgtg cgacttcttc ggctttgact agttttccgt tcccgaaaat
    60421 ccctattccc gcagtaacga gtaacagtac actcattccc gtgacaatca tttttttatt
    60481 catttttttc tccccgttct ttttttatta ataaaacagc acctaacaat aaaagaattc
    60541 ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg gaatacggac cattttcctg
    60601 attgacctgg attgcttgga ccactcggct ctttcggttt gtccgttgtt tcttttacgg
    60661 tctcgttata aacacgtggt gttgcggatt cataggcaga gactggaact ttcccggatt
    60721 ctaattcagc catctcctgt ccgttaacta ctacatattg tggttggcct tttgcatcca
    60781 cccaaaattc agggatgatg acctcgattc tcttacttgc ttcatccatc tcgtaacctt
    60841 ccacaccttt taattcttca aaataatagg tgccagaagg caagaaacgt tgtcctgtcg
    60901 taacaaggcc ctctttatcc gaaatgaatt tgcttacatt tttgtcattc aaaggatcat
    60961 tgtctgctgg tttgatccat tgatttttca agtcattagc aggagccata tctaaataat
    61021 atttcccccc ttctatcatc tgatatagag caaaaacagc accttctaat ggttttcctt
    61081 tttcagttgt tcctctttga cgtccatact tgaagaagta tggatctctt agataaccga
    61141 catttttagg atagatatga atctcttgca gttcctcggt tgattctgtc gggtgataaa
    61201 ttggcaaaat agcagcaatt gggatagctg tctgatcgat atcaacatcc aatccaactt
    61261 ctggatcaat cgattcttcg aaaatcaaat aaactgcatc ccgatcttgg tttttcttag
    61321 gtgctttgat acgtgcaatc ccgtctccta atccgccaac cgtatctttc ccagttgtta
    61381 ccgaagtccc tatttggaca agcctttctt ctgtgattag ctgacggata ttgtttctgt
    61441 tcgtttcagc gatttgctgg acgaattctt taggagtcat gttttcagca gctttttttt
    61501 catgataata atcggtcatg tcgtaaatgg caaatgtcgc tccatttagt ggcaccgtct
    61561 gtgaaatgat atctgctgtt tcccctgctt cctcagagat agccaagcca tcattttcat
    61621 ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat ccgtttatgc aacacgaatt
    61681 ccacgacatc ttcccctgat tcttctgccg acatcgcatg tggaagaagg actgctgcaa
    61741 gcggtagtaa aacaagtaat tgaagcatca aacacaacag ctttttcatt accttgctcc
    61801 ctccttttta gattgtctga caaacaaacc ataggctgct cctgcaagcg ccatgaagaa
    61861 tgcagcaagc aggatataga ataatcgtcc ggatcctcct gtagcaggca acggattttc
    61921 aggatcgttc ccgacactaa gctgtaatct gattcgattt gtctccaaaa gttcatattc
    61981 taactcttgc tgtagatcag gcgtctctgc ttcttcgttt ggataatacg aaatctcaac
    62041 ttttagtgta cccgcttctt ttcctggaac tacccgatca ttttctatgt caggttcttc
    62101 tcgataacta atttctaaaa taaagtaacc tggaagtttt ctatagctgt caggtgactt
    62161 cacttccttg atccgataga ccccttccaa caagtctgaa gcattgaata gggaagaatc
    62221 gtttggatct ggtgccaagc ctccctcgat gatttcatac tctcctgcac tattttgttt
    62281 ctcaattgaa aattctgcgc cttcaagacg tcggctattc atactgtcaa ttttcaaaag
    62341 ttccaaatcg attggcgcta gttcatcttc taaggttact tgtagtacac catcgatgat
    62401 ttcatagcct tccggcaagg gagcagtttc gtcttcgatg accgtatctt caatgataaa
    62461 cttaccttct tcattcagtg caaactggaa cacttgatca gatagccgat acccatttgg
    62521 tgcgacagat tccgagacct catattcacc aatagacaga tgcagaggtt ggtcgtaatt
    62581 taaatcgaca tacttttcta ctcctacggc acgagaatag aagtatccga tcccaggcaa
    62641 acgtttcgat tcttctggtt ctaacggatt accagtgtat gctcgataca gcgggaagga
    62701 agaatccccc actttcctga tatcgaaacc tgcaccatct aatgtatggc cttcatggtc
    62761 taattttcta actcggatct cccgataatc aaacgtattg taagcagtga atgctaccca
    62821 taaacgatcc tcttcatctg ttgtatacgt gagatattgc caattttctt cacctgtttg
    62881 cttgagttgg atagtcccta tagcattatc gtaaagtcgc aagatccatg tgtcattttc
    62941 atcaggttct ttgaaacctt ctgggttctg gctctcaatg attttgtatt ctgcatagtt
    63001 ggtagtttct tcactatcct tataaacaaa tgaatctggc tctccgattg gatgaataac
    63061 tttctcacca tccacgatta catatttccc gtcttcatct actgaataga acgtgagtct
    63121 ccctttctct tcctctactt cgttcacacc agaaagccct ttcgctactg gatatccgat
    63181 ttccagtccg ttaccatctg tttcataaag ttcaaactct gcgccattga ttggcatatt
    63241 actgccttca attagtttat tgatattcat gtggattggc ttgaattcat ttcgcatttc
    63301 cagtttgaca tacaactcat catactctgt gccttctatg ttaggctctt gtacaacaga
    63361 aagcttgtga tattctcctt cataatagga attcggatct ttaccttccg gtccgccgac
    63421 tctcgaacca gatgtatatt catctacaag ctcgtagtga cctaacatct catcttcgtt
    63481 ggctgcatat tttttgattt ggaattgata cgtctcatct actaactgat aacgtggtgg
    63541 tccagcgatc tctctgatcc aaaatatgtc gctgactgct ccagtttcat ctcctaaaat
    63601 cggcatcttc gtttcaaaga tcgctattcc gtccgtggta gttttacttg tttcgattgg
    63661 ttcggcttcc ccactctctg gattttggtc atataatgca aattcgactc cagccaacgg
    63721 ctcgccattt tgacccttct tgctgacttg gaaattacgg cctttatgtt cgtaacgaat
    63781 ggaagaagat gggaaataca tccgtccagt agtgatatca ttctcataat cctccaggtt
    63841 ctgaatatag gccatattgt tcactgtgca aaaatttccg tcttgagctc ccgcatcaag
    63901 ttttacttgg tacttgatcc tgaccatttc cccttcacct aaagaaatcg gagaaaattt
    63961 ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc gccactactt ctggtggggc
    64021 ttgtccatga cgttcttcat cccatatttc tggctcttgg tacttcatgc cgttttctcc
    64081 tggatctaga tggtaaaact gaatatctgc cgatctgcca gctccaaatg gtgagacatt
    64141 aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt ctcttgaagg tagaagagat
    64201 atcctccaag gctgtaacaa tgtcattctt gttgttcgca ttgtaatatc gcggtgttac
    64261 gccatcttct tctaaatcag caatattttt caatacattt cgtccaatag catctagtcg
    64321 ttgtctcccg ctaacgtttc catcgattcc taaaccaatg gagaagatac ttggcgggtt
    64381 ctcttgatac ttgtttttca gccaatgatg ataagcaact gtgttgatcg cagatgactt
    64441 ttcttgcgaa gtaggactgc cattcgtatt gttattagaa gaaccatcac caacccagtg
    64501 agtcgcttta ttatctcctt cttttacctc tccataacga tagtgtacat ttacttcatc
    64561 ttctggacgg ttaaagtcag atgcataggt aactggatga gtaaaccctg cattagaagt
    64621 attcccagaa aactcctcaa aatttctgaa caaaacgtca ttatcttcag caatcttatc
    64681 ttccatcaca gtccagttgc tccaagctcc attagtgctc gtacgataac ttgactgaat
    64741 cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg attaggattt tttctggatt
    64801 tctattttct ccgccattgt ctttatacaa tgtttcatag ccatttttaa gccctagtgt
    64861 aagcggagtt cctccgattg gtgtacgatt taatgctgta ttctcacttc ccgtcaaacg
    64921 attgatatca tttgtcaatg gaaagatgtc cgaactgatt tgctcatggt tattgatagc
    64981 tgtactatta tggtaaaaat tcaccatacc gattcgaata tccagactcg ggtcagagag
    65041 cagatcttta ctcatttcgt ttactgcctc aatcaacgca gcatttttag tttgactatt
    65101 ggtcccagcg gttaattcac tcatactcgc tgacttatct agaacaaaaa cgatatcgat
    65161 tggactgatt tcctttttct cgcccccgat gacatctaga tagacattgt aaagggttgt
    65221 tgcatcttca ggatgtagat cagatgctgt gctgcttggc agaacaggtt ctacccattt
    65281 tttgatgtac gccccgttat aatccaagta actgttttca aaattccgtt catttcccca
    65341 aagctgaacg gtttgagctg gaacgtttct atcttcttcg cctgcagttg atccattatt
    65401 agtagcatag tcgtaatttc gccagttcgc tcccccgttt gtataatcac tatcatcgat
    65461 caagttctct ccgtcatatg gcgagccttt gtctccttga tagcgttcat tgctttgtgt
    65521 ccaatttcct aacacttttg tatagtcatt cgttgtaaac ttcgggtagc gatgctgttc
    65581 gttttcaact tctccgctag gatagatata ttcatagggg tcttgcgtag ctgttggccc
    65641 aagacgctcc aaaataccgt tgaataactg gcgttgaatg cgctggagtg cttgaccgct
    65701 gggtacgatt ggttcgtcca gcttttccat ctcattttct tcgctacgtt gaatttcagc
    65761 ggaatcttct gtatcagttt cattttcttg taattcttgg ttatctattc tttcatcaac
    65821 caccacttga agaggtagtt acccttcgtt cacatcgggg atcttttctg tttcaaaaat
    65881 caatgtgccg gtttctgctt cttttgaata aacttttccg acataccatt cttgaccatc
    65941 gatcgtctcg acttttaggt cttctccatc ttcatcatag gaggatagac ctgttccacg
    66001 aacgtttttt acggtaccaa tcccggcggc tgccgcatcg attgctaaac gtattctacc
    66061 ttcattggca ctttcctttt tttcaaaagc cagatgccat tcaagggttt cttctttttc
    66121 aatatacttc ccttcaattt ttgcatagtc ctcatctaag aatacctcat cctcctttgt
    66181 ttctgttgac tcagcagcta catccagggt cgtcatatga tagactgact ggaaatatgg
    66241 tccaaatagc aaactgacag ttactaactg caaaagcttc aattttaacc ctttcacatc
    66301 cttatactcc tttcaaaaat atttgtcttc tttcacaaca atcaacaaaa caatgcccat
    66361 ctaattataa tttaatttaa ctttaatttt aaatcaaatg atatcctttt tagttaaaaa
    66421 acaccaatta tacaacattt attattaaaa ttaaattata aaattttata acgttctcat
    66481 ttaacaaaac ttaagttatt aagacaaatg aataaacaac tacgctttcc tcgaaacaaa
    66541 aaaataaagc acaaatgcgc atttacgcac tcatgcttta ttcgtacaat taattcagat
    66601 aacggcagcg cataggatgc caataacact tcctaaaata gctcctccta aaatgtcagt
    66661 aggataatgt aaaagtaaaa aaatcctcga ataagcgatc aaacaagcaa ataaaaaggc
    66721 taatattcct gcaactggac ttaattcgaa caacgcagct actgataaaa aggctagcgc
    66781 tgtatgtcct gaaggaaaag aagaagtctt cggtttactt gtgtaaagga caagccgacg
    66841 atttttttca taaggtcttt tccgtcttgt cgtttttttg ataaaaagca aaccaacaaa
    66901 aaaatagatc aaactgccga taagaatggc tagaccatat tctctagtat caggtatcaa
    66961 gactaaaaca gcagcaagga gcaaccaaat aaaaccacca ttagagatat tactgataaa
    67021 tttcaaaaaa ttgatttttc gactatccgt tttccgttgc ttggcgaact tgttgataat
    67081 actatcatcg attttagcaa tcaaacgcaa catgttattc ctccttttta agaacctttt
    67141 cttgcgtacg atggataaaa agcaggactt gaaaataaaa caagaaactg aaacctaata
    67201 aagcaaaata gattggtcct gcaaaccaga atgcgacaag aaggatcaac gtgcctgcca
    67261 aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa aaatgcagta atccaagaag
    67321 cttctttttg ttccagttga agcaagattt tgtaactaaa gagaagcgcg cttaatagaa
    67381 gcaaaaacaa cgtagtatac atcaatgtat agccaattcc cccaccccaa tagcggaaaa
    67441 tctgataatc gatcaataga agaagaaaat aaacacttgc taaactatct tgctttccat
    67501 aaagagagaa gttctcacga aactttttcc agaatagtga accgagcttt ttctcttcat
    67561 tttttttgta atgataaatc atatacagaa ctgttcgact tgcagttcct aatgtgaaaa
    67621 caggcaagac gcacaggaac catagtagct gtaaatggat aagacgtgga atccattcaa
    67681 tgatttctaa gaaataatca ttggcttttt taccaatcga tcgattcatc atccttttga
    67741 acctcctgtc aaatccatcc cttcaatgaa ataacgttgt gcaaaaaaga acagcaaaat
    67801 cgtcgggatc aagacaagtg ttgctcctgc catcagataa ttccattgtg tcgttgcttg
    67861 gttctgaaaa acttgcaagc caatctgtaa cgtgtatttt tcttgatctt ggatatataa
    67921 cagaggacct aagaaatcat tccaagctgc gttgaaggaa ttgatcgcaa tggtaatcaa
    67981 ggcaggtttc gtcaatggaa gcatcaaatg actccaaata tacaaatgat tcgctccgtc
    68041 gatttcagca gcttcgatca attcattatt gatcgataag taaaattgac gcatcagaaa
    68101 tatattgaac gcattgccga agaacgatgg aacgatcagg ggcaaataag tacctaccca
    68161 gccgatcttg gagaataata catattgagg gatcatcgtt acaaaccccg ggatcatcat
    68221 cgtagaaaga accaaagcaa acatcagctt tttcccagga aaatcaagct tcgcaaatcc
    68281 ataagcaata aaagaatttg aaaggacatt accgatcact actagcacag tgatgaataa
    68341 tgtatttctt gcatagcgcc aaaaaggaaa ggcggcaatc gtatccagat agttttccca
    68401 tacgattttt tctgggaaaa aggtcggagg ataacgaacg atttcttcca ttggtttcaa
    68461 tgaagtaaac accatccaaa gcaatggaat gatcaaaatg attcctatta ctgtcatgag
    68521 gacataactt agtatttttt ttgtttgccg attcacactg gtctttttga aataatccat
    68581 catttgccgt cacctccaga ataatagacc cacttaggtg caagcttcaa attgacaaac
    68641 gtcagaacca acacgatcag aaacaggatc attgacacag ccatcgcata acccatatca
    68701 aaagctacga acgccttgtt ccacatatgc agattataaa aaagcaaaga atttgcaggt
    68761 ccgcctgttc catttttcgt catgacataa gcttcttgaa aaatttggaa agaaccgatc
    68821 gtagaggtga tcacatcgta aaaaataata ggagtgatta atggcaaagt aatacttttg
    68881 aactttcccc aaacgcctgc tccatcgatt tctgctgatt catataaaga tctaggaaca
    68941 ttttgtaatg tagctaagta aagtagcatt gctcctccag aactccatat tttcatcaaa
    69001 atcaacgcag gtttcgtcca ttgtggatca aacagccaag ctggtccagg gatatggaac
    69061 cagcccagaa atgtgttgat caatcctgca gatggagaaa gcagctgcat ccataagatg
    69121 tagactgcta ctcctgataa gactgccggt aaatagaaag ctgtacggaa tacactgatt
    69181 cctttgattt tttgattgag tactgtggct aaaaacacac tgaaaatcgt cgtcagcggt
    69241 acattgaaga tgacgaaata aacggtgttg tataacgatt tccaaaataa atcatcgtga
    69301 acgaacattc ttttgaaatt tgctagacca atgaaattca tcttggatgt caaattataa
    69361 tcggtgaaac taccaataac tgaaaaaagc ataggcccta gcataaatac caagaacccg
    69421 ataataaaag gcgagataaa taaataggcc catcttgctt cttttttctt tcggatagat
    69481 aaacgcttca aattttcttg cctcctctgt acctagacag tcaaaaatgg attattgatt
    69541 ttgcttgact aagttttcta ctgctttttg tgcatctgcc aatccttctt ttggtgattt
    69601 tgttcctaaa agaatctggt caatctgttc attcactaat gtcgtgtaat ccggagcatc
    69661 taaaggaact ggtgtgatca ccgtattttt aaagttttcg tccgccattt gatagatcat
    69721 ttttccttta tccgttaggt tgtcattatt cactaaattc tcattggctg tcttgctcgc
    69781 catgatatca aaactttttt cgccgaattt ttcttgtact tctggagaag aaagatattt
    69841 gatgaattca taagaggcct caggatcttt tgctccgtat ggtacttcca agacgaatcc
    69901 gccaccccac gaccaatggc ctgaaccttc ttctttttct gggagctgca tcacgccaaa
    69961 atcaaaatca tccggtgcat tttccatcaa actagagtaa taattgatat tttgggcacg
    70021 catggctact aatccggaaa taaatggatc agatacacca gacccaaatt cggcttctaa
    70081 tttattgatc gtatttttcc cataataatc ttgccagtct tggatccact ccaaggcttc
    70141 cactttattt ttagtatcaa tcttgacttt ttcatctttg tcaaaccaac tagtcccgtt
    70201 atctgcgttt agcgcccata catcagcccc taaattccat aatggataaa aaccgatgcg
    70261 tgtaaattct tttccttctt ttttatctag tttacgtgct gtttcttcta attcatccca
    70321 agttgtcggt agatcttgtt cactgattcc agcttcttta aataactttt tattataaaa
    70381 aatgacttgt gtatctgtat tgaatgggat cgcataagga tcaccttcat attctactgt
    70441 atcccaaagc tgcggataaa aatccttaga agtgtctttt tctacatatt tggagagatt
    70501 agttgcttgc tgtgcttctg ctctttgggc aacggaattt atgtcctgta caataacatc
    70561 gggtgcattt ccagctgtta ttgcagataa agatttagtc cagatgtcac cccatggctg
    70621 atacttataa tttacatgga tctcgttttg tgattgattg aaatcctcaa tgatttcttc
    70681 gatagcttct tttcgtgcac cggatcccca aaaggaccag aaatcaatat tttttcttcc
    70741 atcacttgtt ttttcagaag aatttgctgc acttgaactg gcatcgcttg cattacttga
    70801 tccgcatcct cctaataaaa acaatgctga acttgccagc aaccctgtaa acaataattt
    70861 tttcatattt tacctccaaa ttttaatgta accgatgccg gttttaatat aacgatatca
    70921 ttttgttctg aaaataacaa tttataaggt atgattctaa aaaaattatt aatgatacca
    70981 atactttata taattcgcga gcgctttctt tgaatttttt aatctttcgt agcagaatga
    71041 gaatgtatta aaaatagatt aggaggaatt ttgatgttta gacaccagaa agaattgcag
    71101 tttgaagcaa aaccagatcg tccgaatcca ttaatcgcga aatatctgca ggagctgatc
    71161 ggcggccaat atggcgagat gagtgtagct atgcagtacc tgttccaagg ctggagctgc
    71221 cgaggagaag aaaaatataa agatatgctg atggacattg caacagaaga aatcggccac
    71281 gtggaaatgt tggcgacaat ggttgctcgt ttattagagg gtgcgcctgt tgaagatcaa
    71341 gaagcagcga tgcaaaaaga tccaacaatc ggtgccatta tctctggaat gaatccacag
    71401 cacgcgatcg tagctggctt aggacctcgt cctgctgaca gcgtgggcaa tccatggagc
    71461 ggtgcctata tcattgcgag tggcaacttg ttagcagact ttagagctaa tttaaatgcc
    71521 gaatcacaag gaagacttca agtagcacgt atttacgaaa tgatcgatga tcgtggcgta
    71581 aaagatatgc tgtctgttct ccttgcaaga gatagctatc atcaaaatct atgggaatgt
    71641 gcagtgaaag aattagaaga aaaagaaggt tcaatcttag tcccaagtac tttcccgcgt
    71701 gacaaagaac gaaaagacat tgcttatgac ttctataact tctcagaggg agaccaaagt
    71761 agtgaaggtt cttgggctag tggcaaagca ctggatggcg aaggcgaata tcaatggttg
    71821 aaagaaccta agatcgaagg cgctgcacca aaattagaac cagtaacacc aaaaatgtat
    71881 gggacacctc cattcaagaa ataaatatct acccgtagaa acacccgttt tttgttccac
    71941 acgctttgtg agcaaaactg actaaagtca ttaatcataa ccacccttca aaagggtggt
    72001 tttctctaga gctataagct caaatcaccg gccagcgcct aaagacgctg gctttcatat
    72061 tttatgttca agccatattg cctttgccag ttttgcccac ctcttaaaag gtttatgtac
    72121 tactccttag cccttaaaag gatcgtctta ctctcgtaca ctcagcttat ctaacgcact
    72181 atcatgtttt tcttgttctt gaatgtactt tttgatggtc gcttcatttt gtcctacttt
    72241 tgtcacatag tatccttcca cccaaaagtg tcgataccca aatttatatt ttagatttgc
    72301 acaatctctt gatgatctcc tgaatattgg ctcgatattg attataaatt atttttcttc
    72361 tatactttgg tgtgaataca atgtggtatt tacacatcta ctttgtacgg gctaaactat
    72421 ttccctttat tgctccaccc gcatagcaag tggttttgta tttcaatcgc tcggcgcgct
    72481 caattaggtc taaagacaat aaatctaaaa acccgctgct tcactgacag aaacaacggg
    72541 ttttcagaaa aaaatgaaat gaaaaagatc tcttacggca atctatttta tttttttgat
    72601 tttttataaa tggaaaatgc ttcaagaagt ccaagaaata aagccgtata aaaacaagaa
    72661 cctatgaaat ctttatttat tagatattca acagaaatcc cgataacact agccaacaat
    72721 atatttatca gaagtgtaaa ataaggatgc tttttataga atagaactag tgttgttttc
    72781 atagactctc ctttcttcat atttccaatt aatcacaaat tcacggcatt actagaaaaa
    72841 ttaaaggggc gcagaagtgg aaaaatactc ttcgactttc cctacaaacc aggccatctt
    72901 gtgtttaata actataccaa atctaaggta cctctaaatc taaattccat ttgtggcggt
    72961 gacctccaat ttttaactct tctatctccc atccagtata cataaccttg atacttcgac
    73021 cacttatata tcgaacacac aaatacctat ccattgcagg agtactacct aacttagttg
    73081 ctacttgcat ctaaataaca gctgaaaaga taggacttac tcttagtaaa gtatctgaac
    73141 tattaatttt taaactatca tttttatcct caactacatg cacatctgtt gcaacttcac
    73201 tttctgtctc atccagataa atgattaagg aatcgggaat tgcaatatct tcagctgacg
    73261 ctggaatagt tgagctaaat tagtcatcat atctttatta taaaataacc aacagcaaaa
    73321 aatacaatga aaaacaaact tgtggatttg agtcaatatc ttggacacat tttagtagag
    73381 acggttaagc cattttttct tttgctaatt cttcaaattc ctgtggggtt agatagtgaa
    73441 tcgagctatg gattcgattt cggttataaa atccttcaat gtagctaaat agcgctcgat
    73501 ttgcttcttc aaaatctgag tagctagtcg tgtagacttc ttcttttttc aatgaggcat
    73561 ggaaagattc gattccagca ttatcataag gtgttccttt tctactataa gaatgcctta
    73621 ttttgttggt tttaagccat tgttccactt ctcttgctgt gtattggctg cccaagtcag
    73681 tgtgtagaat cattccttct ggaatgtgat aatgtatttt tgctttattc aatgtttgaa
    73741 tgacacaatc cacagtcatt cgttttgaaa atgtataact aataattttt ttcgtgtgta
    73801 aatccatgat tgaagataag taacaccaac catttttctt agtaggaatg tacgtaatgt
    73861 cagctgccca tttctcacag atcgtttcag tagaaaagtc ctgatttaag agattctctt
    73921 ttgaaatgat cggtttatta gacctttgag gtctatattt tttaactaca atcgacctta
    73981 aatttaattg tttcattagc ttttggacat gtttaagaga tactgaaatc ccttctttta
    74041 ataaaacttg atggatcttt gtggcaccat agcgttgttt attcgtaaaa aaaattgttg
    74101 aaatcttctt tttcaactta ttatttctga tttctgtagc tgtcaacggt ttattcttat
    74161 aaaaataata gacacttcta gggatttcta ataaccgaca taacaaagaa acagtgtaat
    74221 ccttacacca tttttcaata aattgaacaa gcgaatttag gttttccgag agaatatggc
    74281 tgcggctttt tttaagattt caagttcctc atttaaacga gcattttctt ttctcagttc
    74341 agctacttct tttccagtca gtcctgtgga ctgatcaggt aaatataaat tcttccattt
    74401 gtaaatcgtt gcttcagata agccatattc tttcgctaac cctcgaacag aacgtccagt
    74461 ttgattcagt tcaacaatca tttgtttaaa attttcttca tatcgggtca taaaaattca
    74521 tcctctcgta gataagttta atttattctt gtctctacga aaagctgtct aagatttgat
    74581 actaacacca cttggaacta atgtatcatt aataaatgtt gaaaaattca gcaactcatt
    74641 actgtatgat tttagcagcc caaccaacat ataccctata aaagctaata agatggttag
    74701 gaatccttta gaatttttac tcattcatag acacttcctt aaataacttt tattatagaa
    74761 ggtattgtaa ataataatat tgacaaaaag tgactcaaaa taaaaaaaac cttacattat
    74821 actggaatga actgtattga tagtgtacct aaaagctcta ctgacataag atcgtgtaat
    74881 cggtaaagta attttattaa ttatacggga tgtaatcaat tagagaataa actaatcata
    74941 aaaggtactt ttacattcat aattgtcgct ttgagattct actttggttc actatctgac
    75001 ccaattgcac attttcgatc attacaagta ttggtgtcgt tagaacaact aaataaaaac
    75061 tagcggtaga tttttcagaa tctatgctaa tttctgtatg gatgttccag tgatggcaaa
    75121 tttctctttt cattgttttt cttgtcgcat gatatgcctt tttgtgttat tcagttaaac
    75181 tatagaaatt ctttcctaga cagatcttga tcccaaattt tacgtttttg agcatcgata
    75241 tagtttaaaa tgacattact catatctaaa gagtttagat tttttaggac taaaactgtc
    75301 agttgttctt tttcttcttt ctgttaaagt attgtcgcga cttttcgtat acgttaagat
    75361 atgtcgtgaa aaaacaagtt ttgtgacaca aaaaaacgaa tgacttgagg aaatcacctc
    75421 aatcattcgt ttaaaatgct atatattctt tagtttaaga tacggaaatt aatgccatcg
    75481 accacactag tagaatgaac gacatttact tggccttttt ttaatttcgt tatgtttagc
    75541 atataaaaat attatagagt ttacttacaa tgcttaaaac atatactgta taatctgatc
    75601 aattttagcc atgtcttgca atggtaagtt ttctattttt ttgagttttc gttccttaaa
    75661 atcaagagat tttaattgtg taataattac ttgtcctttt atatctagct cttcaggtaa
    75721 tgagtaacgt gtcggtaaat tctttatagt ggaagtaatt ggacatatga ccgaaaacat
    75781 tgttttacgg ttaaattcat aacgagagac gactagtcct ggtcgtcttt tttgaatttc
    75841 ttttcctacg gagggatcaa aatcaatcca tacaatatca ccttttttag gaatataaat
    75901 tctttcttct gacactataa aatttctctc ccttcaggag ttaaatcttc ccattcgtct
    75961 ttctcataat actcggcctc ttccccacca ctaaatggat cttcaatttt tggaactaac
    76021 gtaattgttc catcatcaga atacacaacg atatattctt ggttttctga aggtttcttt
    76081 ccgttatcag aaggtaaagt taccactaca gaacttcctt gtaatctaga ttttgtaaca
    76141 agcattatca tcactccctt aataaaagta tactatataa cactaagtaa cgcaaaattc
    76201 ccctttgtaa actatctaga aaattgtttt gtttaaagta tatcttattg gatataaata
    76261 gaaataaatt gtagccagtt cattttttct ttaactaaaa aaataatcca agaaacattg
    76321 aacctatgga tccaaaagct acccaaatac tatagctaac cccccgctac cttcaatttt
    76381 gcagataaaa cgctttggga gaaaatttca aagacaacag gccatcctat catgcccgat
    76441 tataaacaaa aagctggcta ttccttttgc tctgacaaat ttcaattggg aaagttcacg
    76501 aaactagcag gtgaagaagt ttcaactgtt cggatcaaag aatgcccgct tcaaatagaa
    76561 acattggttc aacgaatttc aactagacaa gactttgcta ttgtagaacg tgagatcgta
    76621 gctatttttg tagaagaagg gattttacat gatccaactc atatcaatgt ggataaatgg
    76681 caacctctta tctataaatt cagagaatat acaactgcca accagtcgtt aactttgaat
    76741 tttagattcc aagaattcaa agagtcataa tgataaacat cgttaggtat aaataaaaaa
    76801 gactcgcagc acgagtaaaa aacaaataga agctatacat tagaaaggtc gactgtgacc
    76861 ctatagatgc agtatatgca gcttatgagc atttcttctg ttctctttgt ttttgggatc
    76921 tgtgctgaag tctttttcgt tttttgccgc tctttctttg aaaaatcgat tatgttatac
    76981 cttctccatt actaattcag gcatctgctg agtaatgatt tttcgcgcaa aagaaataac
    77041 tgttacccaa ggttcgattt gttcttcagt caagacaagc ggcattcggt catggattgg
    77101 tgcgactgtg cggttaggtt cagtagtcat tatgattgat tctgccattt tttcatcctg
    77161 atggctacga taaaaaccgc caatatacac tattttttcc ttatttgaaa acataaattt
    77221 gtctttttct tcattccact cattgggaaa acacaacgat tttgcaaaaa tggttgatga
    77281 aaggtctttt tttcttctac tgtctctgca cgggcattaa tcatcaattg tcctttttta
    77341 aatccggtaa atccccactt catgatttcc ggagtgagga tgttttcttc ctcttttctt
    77401 aacgtcacaa caagatttga cggaaaaact tctccagctg ctaattctgc tgcctgcttc
    77461 ggttgtttcg tctgggcttc tcgataataa ttctgaagga gctctgactc tagatcaaaa
    77521 aaataacgac cacacatcct aatccctccc aatctttttt tctatcatac actgcaacaa
    77581 gaagttcgca ccaacaaaac gctttcaatt tttgtagaac taaaaaagtt gtgacaagtg
    77641 acaaactctc cagtgaatgg tattctcctg ccaactcctc ggtcacaagt cacaatattc
    77701 aacaaacatg agaagctgct ttttgaaatt gttccttgtg actcggagtg aaacggcagg
    77761 cttacgacct ctgggtaaac ggtgttcaaa agccagtttc tcggtattaa gccaaattta
    77821 tgcaaaaatg tagaaagcta ttttcacaaa atttttctta atactcgaaa ctaagcgact
    77881 ttttcacaac ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagcccaa
    77941 ccaaacgaaa aatatgagca gctattttta tttggctgtt cttattactt gatgcagggc
    78001 agctttttca caacctctcc actaaacggt gttcaatcag ctaaccttcg gtattagctc
    78061 aaaaaacggc aaaatatgag gaactatttt gccgtttgtt tctctaatac tcaggtcaaa
    78121 gcgctgattt cacaacctct aatacacggt gttccagaag tagcttcttc gaaaaataag
    78181 ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat ttcttgaagc
    78241 tgaccacttc tgtcacaacc tctaattatt aaagaacctt ttgcgaagtt aacaatcttt
    78301 ctttgatcaa ttgaaaattc tgcctaagta gtgatagatc ctgtgtgact ttcaacaata
    78361 agatacttcc ctggatttca gcaatcaacg ctttggcttg acggtctgct tcttcatcgg
    78421 acagtttttc ttcagaaagt gccaggatat tttgtttcgt atacttgacc cattgattga
    78481 ctaattctag tagcaacaga cggtattctt catccactgt actcaactca ataatcaaat
    78541 tacctacagg acagccatga taagtgatct gtgtctcatg atcagcgaaa atccagtcca
    78601 acatttcttc taatgcttct tctggctgtt ttccagcatt taagatgtct tcgaacaatt
    78661 ctgtctgcca tacgtccata tgcgcatgga tcaccgctag acaaacttct ttttttgaag
    78721 aaaagtaata ataaaattga ccttttcctg tatcagaagc tgctagaata tctcggattg
    78781 acgtttcatg atagcctttt ttataaataa gatctttggt cgcttccaag atcttttcct
    78841 ttgttttcaa tgatattctc ctttttcatt tctcatagtc ctatattata cagtaaattc
    78901 atcatttttt cttcttaatc gtttaaaaaa gactgtgcca aattatctga cacagccctc
    78961 actataaaac tgttctcata tagctagatg ttcattgatt caagaactgc gaggacaaaa
    79021 gcaattccta tcttatgata gttgctctaa tacttcctct gttgtcatca cttgatctgc
    79081 aataaagcca aagttcgtca acgctgcatc cattgcttct tggccaggag caccaattgc
    79141 atctgtcgct accacaacat tgaatccact ctctaccaat tcacgcatat gggaatcgct
    79201 acacaagttt ccgttcattc caccaagaat tactgtgtcg attccatttt ttctcaattg
    79261 gagcgccaaa tcattgcttt ctggtccaaa gattttatga ggagagctga tgatcgtatt
    79321 ttcatccaaa taaggtttca attcttcgat aaaatcggct cctgaacctt cttccactga
    79381 ttcatattga ctttttctag caaacatctg ctgctcaagc atcatatgtt ctcctgcacc
    79441 gccaaattgc catttatggt catgtgggta aaaataatga ggagaaataa agagtttgta
    79501 tcctttttct tttgcttgtt ttaccatttc aatcatattt tcgatcgtat tgtatttttc
    79561 taagatatct tttgtcaaac caaagccacc gcctgctggt ttcaagaact cgacttgcgg
    79621 gtcagtgaga actactgctg tatttttatt attgaacatg gtggattctc cattcgttat
    79681 ttattttaat acatcattta gagcttcact cattgtcgga tgagaataga tttgatctct
    79741 caataacgta taaggaagtt ttccattcat agctagcgaa atcaagttga tgacttcatg
    79801 agaatcttcc gcatagatac ttgcccctag aatcaagtca gtttcagggt cgactaaaac
    79861 tttgaataca cctttaggat cttctaatac ttgtgcttta gggacaccgc ttgtcatata
    79921 cttgaataat ttgtaattga cgccttgtgc tttggcttgt ttttctgtta aacctacatt
    79981 ggataaagtc ggagtgataa atacactgta aggcacagct ttccggttat tcgttgttcg
    80041 tttattctcg cccttcaact gatccataat gattcgataa tcatctagag agatataagt
    80101 gaactgcaat ccgcctttga cgtctccaat cgcccaaatg ttgtctgcat ctgtacgaag
    80161 gtattcatcc acagcgattg ctccgcgatc tgttagttta acatctgtat tttctaatcc
    80221 aagtgatgct gtacttggtt ttcttccagt tgcagccaaa acttttgacg cttggattgt
    80281 tacttcttgg ccatcttctg taaaggtgac ggcagctgtt gattcttggt ctgctacttg
    80341 atctacagat acacctagat ggaattcgat tcccgcattt gtcatgtctt ctaaaatcat
    80401 ttgcgcgata tcttcatctt cacgtggaag aaattcagaa tgggcatcaa gaacgacaac
    80461 tttagatccg tattcattga acattgatgc aaattccaag ccaatatatc cagccccgat
    80521 gatcactaat ttttccggta attgttcctg atccatcgct tgcgtagaat caatcaagta
    80581 gcgacttgta ttcaatcctt tgattggtaa aatgattggt tcagaaccag tattgatgaa
    80641 aatccgttcg ccttcaacaa tcactttttc accattattc gtcacttcga tttgatggtt
    80701 agaaagaaaa cgtgctgtac cgtccatcac tgtcccagtt gcctcatcgc tgatcatatg
    80761 ataatttttg gcgcgaagca tgcccgtcaa tttttctttc cgagcaacag cctctgtaaa
    80821 gtcgattcct ctttctccat tgaaaatcaa tgatttagaa ggaatacagc cgatgttgat
    80881 acatgttccg ccatacatac gtgttgactt ttcaacgact aaaaccgatt caccttttga
    80941 agctaacgcc ttcgctaaag tcttaccgcc ctttccaaaa ccgatcacaa tattttgata
    81001 tttttccatc atttttccct cgcttctttt ttacctaccg attggtacaa aaatatgata
    81061 accgataatt gtctattctc caaatcatct gctttatttg tcaaaaaaaa ccagacaaaa
    81121 agcggtcctt tcacgttttt agtctggttc gatttccttt attcttctaa acaatcgtta
    81181 cttctacatc gatatttcct ctagttgctt tggagtaagg gcagaattca tgcgcatctt
    81241 ctgcaatttt ttgggcttct tcttcgctga tgccatcgat atgcacttct aatactacac
    81301 cgatctgata gccgccatca tctaaattat aaagagagac acgtgctttt actgtggact
    81361 ctgctgtcat tcctgcttct ttgatcatat gttgtaccgc cccattgaaa caagaagcat
    81421 aacctgctgc aaataattgt tctggatttg ttccttctgc atggattcct ggaggagtga
    81481 ttttcatatg catcgagcca tttggtgcct cgacttctcc attgcgcccg ccatggttga
    81541 tcattgctgt ttcgtatgct tttttcattg tactgctcct ttcgattgac catttgctac
    81601 ttggctataa ttatagtgta tgacaagtaa ggcgctttct acaaaaattc tgcttattcg
    81661 aataccagaa tgccgtcttc tactattttt ccaaaaaaca aaaaaatact actcgtgaac
    81721 aacagcgtca tatttgttcc aaaataaata gcaatctttt ctacataatc ttttatatga
    81781 ttgattttaa gatacatata taccagaaag ttgaccccat aaaccaatac tgttaaaaaa
    81841 ataaccatat tcgttaccat tttttcctcc ttttgctggt ctccctacca gcactcgatt
    81901 taaccatacc actttttttg ccgtccaagc aactagcctt tcaaaaagac tggtttattc
    81961 tgctgttaat gattcaagat cagaaaaatg tccgaataat tttgctaatt ttactaacgc
    82021 caacttgttc tttccgaatt catcattttc tatctgtaat actagtaacg gctcatgtaa
    82081 gcttaaacgg atcaaaaacc agccgtttcc gtatggctct tctagatcat atcgaatacc
    82141 ttcttcattt tccgggtcga agttcatccc tttttcttct tccaacagtc gcttcatttc
    82201 ttctaatatc ttgtttcctt gttcgcgtgg ttcatcgctg aacaatttta atcggatttc
    82261 ttgtacttct acgggctgtt tcaactcttt gatttgttca tctaatgtga taccttttct
    82321 ttttaattct ggcaaaagca tcaggatctt tgcgatgaca tatgcaccat catccagaaa
    82381 atagttttcc ttgaatgcag cgtgtccgct tgtttcgatg gctagctgtg tatctttccc
    82441 aagacggtta agttctaatg ctttattgat tacatttcga tagccggaaa tataacgaac
    82501 ttggatgcct cctttttctt caatgaatct ttgtagatga gaagaagtag gggaattcgt
    82561 cacgattctt gttcctggat gctcttttaa tacgattgta cttaatactg cgatcaaatt
    82621 atttcgattg atcactgttc cagaagcact gacaactgca gaacgatcca catctgtatc
    82681 gaaaatgatc ccaagatctg cttcatttgc taaaacagcc tgcttgatac tttccatcgc
    82741 ttctttatta tcaggatttg ggatatgatt aggaaatcgg ccatctggtt ccaaaaattg
    82801 ggaacctgtt gaatccgcac ctaagctatt caatactttt tcagcaaaga atccaccagc
    82861 accatttccg gcatcaacaa tgattttcca accatttagt ggtttgcttt ctagtgttcc
    82921 aatccccttt ttaatttttg tgactaaatc ttgcgcataa ggtgtcaaaa ggtctgcttt
    82981 ttctacgctt ccagtttgtt cgctttttat tttttgctgc tgtgatagga taaaagcaat
    83041 atcttctttt tctgctcctc cttctgaggt aaagaatttt attccattat aataataggg
    83101 aagatggcta gcagtcagca taaccgcagc atcgcacgag aactgttcaa attgagtgga
    83161 cataaacata gcaggcgtag tagctaattc gaaatcgatg acatgtatcc cttgttcttt
    83221 cagactttgg atcaacgcct ctttcagtgc tggtccgctt atcctactgt catgaccaat
    83281 cccaatcgtc cattttttat ttggatcggt tgatttcttc tttttcttta tccagtttgc
    83341 tagtccccag ccgatctttt ttaccatgtc tgtcgtcaag tttacttcat atccttcaac
    83401 tggtaatgcg attcctcgaa tatccgatcc attttgcagc gctttcatat ctttcatata
    83461 aaagtcctcc tcatttattc cctcattttt tccagctttt ctgcaaatcg ctgtgcttct
    83521 tcttctgagc ggcaaataat aatgaatgta tctacaccgg ccatcgttcc gacaacttca
    83581 gggtaagcca cttcatctag ccaattcgtt accacatcgg caccatttcg ttcagtcaat
    83641 acgataacca tgaactgaac agactggata cgcaaaacct cgcgtctaat tgctgtacgc
    83701 aaacgttctt catttaaaga aacagatggc tggttaaata atgtatagcg tactattttg
    83761 ttttcatttt gactttttac taacttcatt tctcgaatgt ctcgagaaat cgttgcttga
    83821 gtcacatcgg cgcctgcttc atgcagccgc gcaagcagct cttcctgtgt cccaataggt
    83881 tgttctgtaa tgatctggcg gatcagtgct tgtcgctgtt tctttttcat attagacacc
    83941 tctcaatgtt gattatagca aaagataagt aatatttctt catattttgg tattttttac
    84001 ttttattttt tgttttcatt caggttgcta acctttttct attttaacac gcaaaatcgt
    84061 cttcattttt tcaggtgctg attttcttgg atcgctgatg taaatctctt tgtgttcttt
    84121 agaagctctt tcatagcctt cttttgcgat gaatgcttct aatttctcaa acgttgctgg
    84181 ttcttcggca tagggcccga cgtgtaagat ttgggcacaa agaccttctt ccatcttttt
    84241 gaatactact tgttctttca agtcttccgg aagtttgcta gaacgctgaa tggcttcttg
    84301 tgctatcgct tctgtaacaa agtcaggctg tcggatcatc aattgataag aaaaatgttc
    84361 ttttttcatc actggttcat gcaaatactt ttcttgcagt ccccattgtc cttccagtgg
    84421 atagacagta tacatctgat aatcaggaat cagccaattt tttttaggcg acatgcgtat
    84481 tgcatagctg actgcatata gacaggctac tcttcgttta aagtcttcct gattcgggtc
    84541 gccgatccct ctgatgctaa agaatgattt tttaggaacc tctagtattt gcgggctttt
    84601 tttcatacta tagctcttgt ctttacgcca ttcaattttt tccatttttc ttcctccgcg
    84661 aaattccatt tagttattta ttatcatacc tctttttgag tgacttggct aatcgtgttg
    84721 acactatttt tcagtttgtg ctagaataag tgaagtaaat aaatcgtaca gataacacgt
    84781 ttcggcgtgt cgagagagag gcggtttcta tttttataat agaaatcact ctcttttttt
    84841 acgaaatttt ttagaggtga tgtaaatgac aaaacaaaaa cagctgcttt tagtacctgc
    84901 agtaattgca acagggatga tgtcttttgc gggcgtattg atcgagacgg ccatgaatgt
    84961 aactttccca actcttatca gacagtttga tttaacgact gcacaagtcc aatgggtaac
    85021 aacgatttat cttttgatga tttcgatcat tgttccgctg tctacttatt tgaatcgcaa
    85081 ttttagtctc aaaaaactct ttttagcttc aaatctgctt ttcttggcag gtataatgat
    85141 cgatttcttc tctcctacct tcatggtcct attgtttggt cgattgctcc aaggtgcagc
    85201 gacaggtatc gctcttccgt tgatgttcca tattatcttg acatttgccc ccctcaatcg
    85261 acgaggcgcg atgatgggtg tcggtacttt gacaacggcc attgctccag caattggccc
    85321 cacttatgga ggcattatga cttcacattt tacatggaat catatcttcc tgtttcttgt
    85381 gcccgttttg tttctttctt tgattatcgg ctggtttgct attcccgaga tggcagtaca
    85441 aaaaagtggt tatttggatt ggataagcgt tttaggaatt tgtcttttgt ttagtggaag
    85501 tctaacattt ttgagtacgt tgggaacagt ttccagctgg attgctttaa tcatcggcgg
    85561 tattggctgg ttcctttttt actatcgaag taaaaaagtg gagcatccac tgatccgact
    85621 gtctattctt tcaaataaaa cattccgctt gtttttgatt ggcttcttag tttatcagtt
    85681 tttattactt ggtgtatctt ttgtcttgcc gaatttcctt cagatcgttc aaggaagtag
    85741 tccttttgtc gctggattag cgatgcttcc cggcgcagcg gttggtgctt tgctttctcc
    85801 tttttccggg aaaatgctgg atcaatatgg tccgaagaag ccaatttttg ctgggctgat
    85861 tctttctttg attggttggc tagcattatt cctactcata ggacacgctt cagtgggtgt
    85921 attgattgct tgtcatgtgt tttatatgat cggtatcgga ttatcttaca gcaatatgat
    85981 gaccaccgga atgaatgcac tgaatgaaga actacaagga gacgggaacg caatgttcaa
    86041 taccttgcag cagttttctg gcgctgtggc tacttcatta gtagcggtca ttatcaatta
    86101 cgtccagcat catacttccc ataactatga agtgtctact acattaggat caaaagcagc
    86161 attaggcgtc ttgttgctgt tgcttctcgt aagctttgct cgattcgcct attatctgtt
    86221 ctttgctaaa aaagcgtaga ttccatatac ggcaggtgtt gcatctgccg tttttttgtg
    86281 tgaaaatggt tgtttgtaaa aggaggcttt tttatggaaa aaattgccat tatcggtggc
    86341 gggatcattg gtatgaccct agccagttac ttagatacat caaaattcaa tgttgcttta
    86401 tttgatgaag ggacaggaca ggcaactaaa gctagcgctg ggattatctc cccttggttg
    86461 tcgaaacgca gaaacaaaca atggtatcgt ctggctaaag acggcgctgc ttttttccct
    86521 aaacttataa aagatttcca acttgatcaa acgatttacg cacaatcagg gacacttttg
    86581 cttcgacctg aaaaagattt agctgaattg gctgttcttg ccgagaaacg aaaagaagaa
    86641 gcgccagaaa ttggaaacat cgaatggctt tcacctgaac agacatctca agcacttccg
    86701 ttattgaaac cagcagtttc actgcgtatc agtggtggtg gtcgtctgga tggaaaagca
    86761 tatttagaac atcttggtca gcgtttagca caaaaacaaa tggagcagat ccaggcaaaa
    86821 gtcactttgc ataagaagag cgattcttgg ctcatcaagg gaccgtttgg agaatacaca
    86881 gctgatcgtg taattttgac acctggcccg gcacttaagc ctttattaca agaattaggc
    86941 tatgctgcag atatacgtcc gcaaaaaggg cagctcttag catttcagac atcttataag
    87001 atgagtcaag actggcctgt tgctatgctt gacggagaag ctgatttcat tcctttcatg
    87061 gatggaaaga tccttttagg tgctacccat gaaaacgatc aaggctggga tttggctcct
    87121 actagcgaag cttataaggg attgactaag agtacagaac agttcttgac tgatccagat
    87181 cagataaaaa actggccata cgagttccgt gtaggtaccc gtgcttatac gtcagatttt
    87241 tccccatttt tcggcgtact gccagatgat ccaagcttac tggctgctag cggtctaggc
    87301 tcttctggct tgaccacagg tccttatatc ggctatctat tagccaactt cttaaatact
    87361 ggtcattggc ctacggaaga ttatcaaaag gacatctcca cctatattac gaaaaatcca
    87421 tcatagaaaa acagcttttt caagtaagga tcccgagcga tattgcgcat ggattacttc
    87481 ttgaaaaagc tgttatttta gttcaatttc tgaatcaaat tctccaaact ttcttttgct
    87541 tcatctggca agagatcttt tcctatctga gcttcaatga atcgtaaacg aatatcaagt
    87601 cgttgtttca ccagattttt ataggacgta tcctcaaaag aaacaggaaa atctggtata
    87661 ggtaaatagt ggatgtcttc aaatggacca aacgacttga attctgccgt ttgttgcacg
    87721 attctttcaa cgattgacaa tgtcgtttca ggtttgattt ttttatcatc gaaatatcca
    87781 gtattcagga catagcaggc tgtttgctgt ttcaaaaaca actctcgaaa agcttgatag
    87841 tcttccctaa gaggatagac acggaaagga ttagcaaatg gttcaatgac tagctcatct
    87901 agctgtcttt ttgtagtgat attttccgcg tctgatcgtt ttgttgctaa tgttgcacca
    87961 aaagacgctg ctaaaactgg gtcattgatc ttgataattg gcggaagcga atcatctttc
    88021 atgatccaaa aaacagcatc gatcttttcg ctaagatgat cgactcggtc gggtgtcgca
    88081 taacgtgatt tgactgtccg cccatttccg tttcgtatat ctcctgttac taggactttt
    88141 tctcctttac ttgtacatgt cacgcccaca ttctgacaag taaggaaaga agaaatggcc
    88201 ggatcatcag acggatagtc ttgtgtttta tcaaagtaag aaggttccaa ggcagtagca
    88261 aaaccatttt ttcgagaaat aacgaaagca tcgtcatgca agatcgaaac agagtgacct
    88321 tccgtatgtt ttgctaaggt aatcgttgat tttccagaac cggacaaccc aaatacagcc
    88381 atcgtatagg tctggtcatt actagcatat tgtttcatcc caccgtggca ggcaataaag
    88441 ccattgcgat ttcccaatgc ccaagcaagc gtcaaagtcg ctttttttaa ttctccaaag
    88501 taacgtaatc ctagcacagc cgctgtatta tggagagcat caaacaaaat gagtccattt
    88561 ggaaatgttt catgtgtcca ttcgggatca caaaagatat aaagatctcc ctcatcaaag
    88621 gaaacagact tttgataagt ctctaagatc ttcgaattcg ctggctgaaa attcagcaaa
    88681 taagaataca aattgttctc aaatccttct ggaatcagca aatgactttg cacagaaaat
    88741 tcttcagata ggccaacgat tacttttgta tggtaaaact ggcgcttgcg actttgatac
    88801 acagcttctc ttaaaatttt ctcgtatttg ctttgttcct tgtctaagtc ctcaaagatc
    88861 cgccgagcac ttgctgttct tcccacaatg cttccatcat tgaatactag tgtcctaaca
    88921 tcagctggta aatctagttc ttcagcatgt gagattgtta aatctgtgat gatcgttcct
    88981 ggactccctt ttgctagttg ataagctgtc ttcctatcaa aaacttcatg aacattatta
    89041 ccgtaaaatg tcgtttctac aatcgatcga atactggata acagtggatt tccacttgtg
    89101 atttcgttta attcgagact ctcttttgta ctcatggctc ctcctcattc cctaaacaaa
    89161 aaaacgtttt ctttattata cattattcga gtttttattt gtactgctgc gctgtgggaa
    89221 gcaaacgagt tatttttcac acaaaaaaac cgagaacttg aataaacaag tttctcggtt
    89281 tcatcatttt ccttttatcg gcttagtacc agccgtttgc taaccagaat gttttagcag
    89341 catcccatga accataacga gatgttacat attgttctgc tacacgttct tgattggcag
    89401 ctgaatagtc gccgtttaag tatgaagcat ctaattgata acggccgatg taacgtccgt
    89461 tagtagctgt gtatgaaccg cctgattctt tttgtgcgat ccattctttt gcagagcttg
    89521 aagttggcgc tgttgcagca gctggggcag caggagctac ttcaactgtt tcaacaggtg
    89581 caacgtatgt atgttcttgc gttgctgttt cagttgtaga tgctgtattt tctgttgttt
    89641 tgttttctgt tgttgctgaa gaatcatttg aagttgggat tgttaattgt tcaccaacat
    89701 aaatgcggtt gatgtttgcg atcgaatttt tttcagcaat tgcatcgatc attgagttgt
    89761 ctcctgcaaa tttttgtgag atcttagata atgaatcacc tgattttact gtataaactt
    89821 catcagcgtg agcatttgta gttcctacaa acattgcagt agcaccagca gcaaaagttg
    89881 tacctaaaac aattttctta aatgaattca tattaaactc ctttttttct ccgtttttta
    89941 ttctttcgac gctattaact ttatcattta gaaatatttc ataggtaaaa gaaacatgac
    90001 atttaatgac aaaataacga attatttaat atttgtaaca tttaaacaaa tatttttttg
    90061 atacaaaacc ataaaagcct tgttgtataa gcaaagtaat cgtttttcta tgttttttta
    90121 tttttgaatg aaaaacgcag attctgtaac attcactgca ataatccata aaaaaaagca
    90181 aaaaaatttt tgatttttat caaattctct taaaaaaatg taaaaaatac aaaaaaacca
    90241 gtaattgtta caacaattac tggacaaaaa ctttgaataa tgttaactat ttttttattt
    90301 taactttctc cgcaataatt tctgggcatg ttccaattcg tttataacga cttcttctgt
    90361 ttctttagct aatatttcat ctaatacatc aagccatttt tccggttctt ttgttcctag
    90421 acgtccaata gcccaagctg ctgttcctct gatgacaggg cggacatctg ttaaacattc
    90481 tgaaatctca ggcaatgccg ttcgatcacc tagattagct aaagcaatca atgcgtttct
    90541 ctgcaaaggt ttcttcccac gccatgaacc agctaaatgc ccaaattgct gtttgaagtc
    90601 tttattagac atcgaaagca ttggctttaa ttttggatat atttcgtcta cttttggttc
    90661 catctcttca tgaaaatgaa aatcttttcc ttgattgtaa gggcagacta actggcagat
    90721 atcacatcca taaatgacat ttcgcatttt tttacgatat tcttccggca tcatcccttt
    90781 tgtctgagtt tgataagaca aacatcgctg ggcattcatt cttccgtcac caagcaatgc
    90841 ttttgtcgga caagcagtca cgcagcgcat acagtcaccg caaccaaatt ctccaggttt
    90901 atcaggctca aatacaatat tagtaacgat ctcaccaaga tagacaaatg aaccgaactc
    90961 ttcagtgatc aacaatccgt ttcgtccaat aaatcctaaa ccagctcgct gtgctacagc
    91021 gacatcgatc agttctccag tatctacttg cggagctaga cgccattcct cttctttttg
    91081 ccatttttct gctcttgttt ggatgaattc gatcaatcgg ttcaaacggt ctctgagtat
    91141 atcatggtaa tcgatccccc aagaagcacg agcaaactgc ccgcgttttt catccctagg
    91201 cacttcttca tggatcctag taggatacgc aagtgcaatg gaaatgatcg atttcggctg
    91261 atcaaatgtc atttctggat aaagacgctc atcgatattt ggatgttcaa agccagaagt
    91321 atggccagct gctttttgtt cttccaacga ttcttttaat gaatcaaaag gttccgccgt
    91381 ggtgaacccg attttgtcaa ttcctaatcg tttgctttct tgtatgattt cttcttttaa
    91441 tgtcatggtc ttcctcgctt gctgttaacg gctgtataac ccataatata gtttttcttt
    91501 tttcagctgg acaaactgga tctgctgatc ggcaatcttc ttttcttcca tccatttttt
    91561 tcttgcagca aatacttccc aataatttgt tgaaattaat tttcttttgt tatctaatgc
    91621 attaaaaaaa ttcaatgaaa ctggttttgt acttaacagt tcatggagcc ttacctcttc
    91681 ccatggcgaa aactcagaca gatcgcggga atacaatact tcttcataga gatttttttg
    91741 ctgtgtgtac gtgaatgttt gcgggatttt cccaggccta gcaatttcta ctagacgatt
    91801 ataaaacata ttcattaatt tgctgttggc aataaattga cttttataat aggccgactg
    91861 gatctttttg attactcctt ctgctttgat gactgaaaat aatgcaggcc atgctttgac
    91921 ggttatttcg tcgttttgtt taactaatac gccaggtgtg aagccgactg gagaaaggaa
    91981 cacaaaataa ccgataccgg tattttcatc taaaggctga aattcatcaa acaaccattt
    92041 gcctatgtac agctcttcat ctggttctgt tgtctcattt tgatttgcta tgaataattt
    92101 agctaattct gcttcaagaa attgaaggtc ttgatccttg tcggtatttt cctgctggct
    92161 gatcaatcga aagacttctt ctttaatcgt atatttatct ttacgtgtaa aattcatagc
    92221 cacaccttcc ttccttactc taactataac ggaatttctt caaaaaaggt atctgtacga
    92281 cgaaaaacag cataattttt tttcatatct cttataaaaa atgcaaggtc tgctcctcaa
    92341 gctagacctt gcacttttca gctttctttt gtttgtgaca aaccttcatg gatcgtttca
    92401 atattccatt tcatcatctg atagtaagaa tctccttgtt ctccttcttt tgctatggaa
    92461 tcagtgaaca gtttatcata gattttcaaa cccgtttctt ttgctacccg ttccatgctt
    92521 cttgagtcta cactggtttc cacgaataaa accggtactt cttttgctct tatctgatca
    92581 atgatcgctt tcatttgatc aggcgtacct tgactttctg tattgatctc ccatatataa
    92641 gctgctggca aatcatatgc tcgtgaaaaa tacttgaatg ccccttcact tgttactaat
    92701 aattttttgt tctcttcgat agaagcaaaa ctttccttcg cttgtgtatc taattctttt
    92761 agtttttcca catatgcttc tgcatttttt ttatagagtg tcgcattttc tgcatctttt
    92821 tcagagaata tacgtgcgat ttcctccaca tattttattc cgttagatag gtctagccaa
    92881 gcatggggat ctgcttttgt atgttcttca ccgctagtta aataaagagg ttctacattt
    92941 ttgctaactg caaaataatc ttttccttct tcttttttag ccgtttccat caagttatcg
    93001 aaccagctgt tacctgtttc aagattcaaa ccgttgtata aaataacatc tgcatcgctt
    93061 gcctttttga tgtcttctgg tagtacttca tattcatgcg gatctgttcc gactggtacg
    93121 atactgtgga tatctatttg atctgttccg acctcttttg ccatgtccgc caagatcgaa
    93181 ttggtagcca cgactgacaa cttttcttta cttccttcat ccgcttggtc agaagcctgc
    93241 tttccgcaac cggctaatac caagaaacta actgccaaga ttaaaaagag tgattttttt
    93301 gttttcatct atctgcttcc tttctgaaat aaaattcctt ttgttggaga aaataaaaaa
    93361 gcaaggataa aaaatgcggt acatgctaac acgatcgtag ctcctgatgg ccaattgtaa
    93421 ctataactga aaaacacacc gacaactgca cttagcatac cgattcctgc agctgtaatg
    93481 atcattttca gtaaatggtt cgttagcaag taagccgtgg cggctggtgt gatcaacatg
    93541 gcaatcacca agattgttcc tactgtctgt aaactgacta cagccactaa tgtcaaaaag
    93601 aacatcaaaa gataatggat cagcgatgtg ttcagcccat aagcttttgc cattgtcgga
    93661 tcgaatgatg tgatcttcaa ttctttataa aagaaaaaga caaatatcaa gacgattcca
    93721 ctaacgagtg ctgtcagcaa caaatcgctt tccctaacag ctaagacatt cccaaataaa
    93781 atatgataca aatctgtcgc actctgggca tatgaaatca agataatccc taatgcaaaa
    93841 aaggagctaa agacaattcc aatcgctgta tcatttttca atcggctccg ctgagtcacg
    93901 aaaccaatca ctgctgctgt tagcatccca aaagcagtgg ctccaaagat gtaactaaaa
    93961 ccaaacatat aagaaatggc tacacctgga agaactgcgt gagagatagc gtctcccatc
    94021 aaagacatcc ctcgtaaaat aataaaagaa ccgatgactc cagaagcaag tcctacaagc
    94081 atggaagtga ccaaagcgta ttgcaggaat tgataattca ttaatccatc aataaaggat
    94141 tggatcattt tttctctcct ccttttacta aatgtctgat gatctcacca taggccaatt
    94201 gaaggttctt cgatgtaaag acttcttgta ctggaccgga agcgatcagc tgtttattta
    94261 aaagaataac ctcatcgaaa tattcttcta ctttatgaag atcatgatgg acgatcaaaa
    94321 tcgtttttcc tgaattcttc aattcctgca agatgtcaaa gatctttcgt tcacttaacg
    94381 catcaatccc tacgaatggt tcatctaaaa agatccattc tgctccttgg gctagagctc
    94441 ttgcaataaa aactctctga agctgtccac ccgatagttc gctgatctgt cttttggcat
    94501 attcttccat ccctactttt ttcaaagctt gtcttgcacg ttctttttct tttttcccag
    94561 gtctttgtcc aattcgtaaa gatggatatg ttcctaaaag tacaacgcct aatacatcaa
    94621 ttggaaagga aagatccaat tcacttcgct gttccacgta ggctattttt ttacggactg
    94681 agtttaccga ctgtccagaa aaggtgactt taccagtagt agctggtatc aactctagca
    94741 aagatttcat aaatgttgat tttcctgcac cgtttggtcc gataataccg gtaatttttt
    94801 gtggatttat cgtcaagttg atagttttca aaacagtttt cccttgataa gcggctgaaa
    94861 ggtcttgaat tacaatggcc gtacgttcca aatcttacac tcctttttag gtttacctaa
    94921 ctttttattt aaatatagtt taactaaaat ggaaagcatt ttcaagtaga atgatgaaaa
    94981 agtttttttc gaattttcct cgcattttat gaaaattttc tgtagaatca catcaagagt
    95041 tcaataaggc taacctaata atgaaaaaca tgtgttgaaa cgtttgatta ttttttcttg
    95101 ttgactcaac aacgaaagga gtttttgtat ggaagaagaa aagttaactc gaagtcttag
    95161 tgcccgtcat atccaaatga tcgcactagg tggaacgatc ggtgtcggtc tgtttatggg
    95221 tgcctcctca accatacgtt ggacagggcc ctcagtgatg ggagcctatg cgattgcagg
    95281 attctttttg tatttgatta tgcgtgcttt aggcgaaatg ctttacgttg atccttcgac
    95341 tggttctttt gcaaattacg cgagcgagta catccatcct gtggctggct acttgaccgc
    95401 ttggagtaat atttttcaat atattgtcgt aggaataagt gaagtgattg ctgtaggatc
    95461 ttatatgaat tattggtggc ctgatttgcc ggcaattatt cccggaatca ttgtcgtctt
    95521 gtttcttatg ctggcaaatc ttatttctgt caaggcgttt ggcgaattat aattttggtt
    95581 ttcgatcatc aaagtcataa cgatcatttt gatgatcatt gcaggtcttg gggtaatctt
    95641 atttggattt ggtaatcatg gtcaggcagt agggatttca aatctttgga aaaatggtgg
    95701 attcttcact ggaggcgtca aaggattttt ctttgcatta tcgatcgttg ttgcttccta
    95761 tcaaggaatc gaactgatcg gaatgactgc tggtgaagca gagaatccta aaaagacgat
    95821 cattgaagct gtccagtcca ctatcggtcg aatcttgatt ttttatattg gtgctatttt
    95881 tatcattgtg agtatctatc cgtggaatca attgagtgag attggttcac cttttgtaca
    95941 aactttttct aaagtcggca ttacatttgc tgcaggactg attaattttg tcgtgattac
    96001 agcggcatta tcaggttgca attcagggat tttcagcgca agtcgtatgg tctatacact
    96061 tgccataaat ggaaagatgt ctaaaaaatt tctgaaacta tctcgtcacg gtgcgccttt
    96121 ttatcctgtc gtagcaatct caggtggaat cttaattggt ctgatcttaa attatcttct
    96181 accaatgttc atcaaccagt cagaaaatat tttcgttttc gtatacagct caagtatttt
    96241 gcctggtatg gttccttggg tagtgatttt gatcagcgag attcgcttca aaaagaagca
    96301 cgcagataaa atgcatgatc atccttttaa aatgccacta tctccttata cgaattatgt
    96361 gacacttgct tttttagcta tcgtattgat tttcatgttt atcaatcctg aaacgagaat
    96421 ctcattgatt attggactcg ttttcttgct ttacatgacg atccattact ttgtacgcga
    96481 aaaaagaacc ggaaaataaa aaaagaacga agcttcacct tagtggaagc ttcgttcttt
    96541 tttattgctt ttatcaattc aattttagcg tctcaccggg agtcaggaaa taattctcca
    96601 tgctcatccc attcagcgac aagatcgttt ctactggtac gccagttcgt tcggctattt
    96661 gatttggacc ttctccttcc aaaactacgg ttgtcgcagc ctgtgaagtc gcgctgttgg
    96721 tattagtttc agaggaatct gttgtgtctt gtgttgttcg agcttgcatt tcagaagctt
    96781 ctaccgactc tgctgtctca gaatcagaag atgttgtgtc ttgtgtgctt gttgactctg
    96841 cttgaagaga ggcgctagtc tgcaaataaa tatcggaaat cttagcgaca tgattcgtat
    96901 aattagccga taattgattg atcaaagtat ctaagtctac accgtcttta ttttctgctg
    96961 cctgatacgc tgcacgtaat tttctgatcc cttcgtcgga gattgcttga agctcacgtg
    97021 ctttttggtt agcaactgct gataaaccag ctattccctc ttgatttccc tgaatttctg
    97081 tctggtattc ttcaatcaat gcaggcgtct tttcttcgat ctttttcgaa taatcattta
    97141 cgattgcttg aagttgctct ggcaaaccat ttgctgtttt ttcttcagaa gtttgtgtct
    97201 cttttgtttt agttgatgac tcacttgttt gtttcgtctc tgttttcttt gtcgttgttt
    97261 ccgttatggt cgtacttttc gcttctgacg aattttttcc atgaaaatat agacccgcaa
    97321 ctcctcctgc tatgatcaaa aacacggcaa ctgctgcccc aatcatgatc atccgcttac
    97381 gagctgcctg tttttgctgt cttcttcggg tcatccgaac attttctccc cactcatttt
    97441 catcatacat ttttttcacc accaattttt atgtataata gcgttatcaa acgcttcata
    97501 ttcttattgt agcaaataat tgtcgctgtg cacattttta tctttgttat ttataagaaa
    97561 atttcaccag ttgagatgat tccaagattg tccgtcgatt tctccttgca gctgcattgt
    97621 tcgttcgtct atctcagcca tcagtttctt tatttcatat aagagcgcac ggtcttgata
    97681 ttctgatttt tcgcttaatt catctaattg ttggatcagc caatcatttg tcataatgaa
    97741 gttcctttca tttcttgcag tgtaaaggtc aagtcttcga tctgctcttt tgcctcagtc
    97801 agtgcttcta cgatatatgc ttgtttttca gattcttctt cctgcatttt ctgattttcc
    97861 tgtactcttt gaataaacca gtcaatccgc tgagtcagcg atggtttgcc ttccaatgag
    97921 agatactgct gataagcaat tagcttctcc caacgttttt cctgggataa atacataaat
    97981 tgtgctaaaa cgaatggcgg aagataggtc atatggaatt tatttgcgat tcgctgatac
    98041 ggcctcaaaa attcggaaat cgtatattct tcttttcctc cagcttggta ttctttttcc
    98101 gccacacctg ttgtcaatac gattcctagt tctttccctt ttaatacatg tgctgctcgt
    98161 tccaagacat tatcttgcca aatttttaaa tgagcaggag aactatacca gtaaaacgga
    98221 aactggaaaa tgatccgatc atgctgggcc aagagctgta gttcagtctc tatatctatt
    98281 tttccgtctg gataacttga ttccaaatga tgccaagtag ctggtaaacc agcagaagct
    98341 tctttgaaaa attgctgatt taaagattct tcgatcgttg gatggctaat gatgataagt
    98401 gtacgcatcc cttttcctcc tttttagtct tcgctttaca gtgtagcata accgccacaa
    98461 gtttcttttg ccgatgcttg tcattttaac cagactaatc aggttgtcca agaaactgcg
    98521 gtttgttttt ccaactgttt tttcaaggta tccaaagcaa tattcttaaa attttcgttt
    98581 ttcatacgtt tacgatagtt cgtagccgtt tctccggtac tctttttgaa cattcggcta
    98641 aatacgacta gactattgaa ccctacttga taggcaatac tttccacgga ttcatccgtc
    98701 agagaaagaa gaaacgcccc tcgattgatc cgtaccccga tcaaatattc cttgatactg
    98761 gtacccatat gatttttgaa tactcgcgac aaatggctcc gattgaccgc taaatgctgg
    98821 gcgatttcct caacagacaa tttttcagca taatgtgcct cgatgtattt gactgtttca
    98881 acagctaaag aggaatgaac cttttgtaca ccaccgctga cctttccgcc atcttttaaa
    98941 aggactgata aaaaacggta ggttaatgct gttaactgta attcattttc caaggtttct
    99001 tccgtatctt tcatgcattc taaaataatg tcgatatatt tttgtatgtc agaagagacc
    99061 atcgtgtatt ggtcttctct gaaaagcgac tgccgaatga tttcttctgc agcactccca
    99121 ccaaatgaaa gccagcaata catccacgga tcttctccat ctgataagta aaacgtcgag
    99181 tctcctggac gaatcaagaa cagatcacct tttttcaatt ggaattgttg atttttcaca
    99241 tgataagatc ctttgccttc catcacgaca tgcaggatgt aatcattgcg aatagcagga
    99301 ccaaaagaat gaaacggcat cgttttagag aaaccacaaa aatcaaaata caattctttt
    99361 tctacttgtt gatgttcctt ttttaaaaaa atcgattgct ccacgtctat ccctccttac
    99421 tcctttagta taatgcaaca aaaagttaaa taaaagtcac agaaatatat taaaaaggaa
    99481 gcgatttctt gttaagttta agtcattaaa agatctttgt tattcgttgt aaccggttta
    99541 cttagtatta tatattgaac aggagaggaa tacagattat gaaaagcaaa atgatccaac
    99601 gtgtgtccta cgctttaggc gcttttggac acgacacatt ctatgttaca ttaagcactt
    99661 attttatggt attcgtgaca agccagatgt tcgcaggaac agataaggca acgaatgcaa
    99721 aaatgattgc tacagttaca agcttagttg taggtatccg cttagttgaa attatttttg
    99781 atcctttgat tggtggcatc atcgataata ctcgtacaaa atacggtaaa ttcaaaccat
    99841 ggttagttat cggcggcgtt gttagttccg tactcttggt agcaatcttt accaatttct
    99901 ttggcttagc tactcataat acgactttat ttatcatatt atttgcaatc gttttcatct
    99961 tattggatag tttttattca tttaaggata tcgctttttg gtcaatgatt ccagctttga
   100021 gtacggaaac aaaggaacgt gaaaaatttg ctacgtttgc tcgtttcggc tcttctctag
   100081 gtgcaaatgg tactactcta gtcgttgtcc ctatcgttac tttctttacc tatcttgtta
   100141 ctcataaaca tattgaaggc gcttcaggct ggttctggtt cggtgtgatt gctgctgtta
   100201 tttcaggcgg tactgcgatt atcactgcct tgggcacaaa agaagtcgat actgcgatcc
   100261 gtcagcaaaa tgaaaaagct gggatcaaag atgtgttcaa agcagttgct caaaatgatc
   100321 agttgatgtg gcttgccctt gcttatatcg cttatgcgat tgccaatgca gcaacaactg
   100381 ccgtattatt ctacttcttc aaatatgtac ttggccaacc aactgaattt tggatcgttg
   100441 gtctagttgc tgccttactt ggtttagtag ctgttccact attcccaatg cttacacgcg
   100501 tcatctctcg tcgctacgtt taccttggag ggatcgcaat gatgatttct tcttactttt
   100561 tctttacgat cgcaggttca agtttgccaa tcgttatcat cgggctagta ttgttctact
   100621 tccctcaaca attgattttc ttatccgctt tgatgacgat cacagactct gttgaatatg
   100681 gtcaatggaa aaatggtatc cgtaacgaag ctgttactct atcaattcgc cctttactag
   100741 ataaaatcgc tggtgctttg tctaacggga tcgtagggtt tgtcgctatc gcttctggga
   100801 tgactggtaa tgctactgct gctgatatca ctgctcatgg cgtaacgact ttcaaagctt
   100861 atgcattcta tgctcctgct gctttgatga ttttctccgc tattattttt gcttggaaga
   100921 ttacattgac agagaaaaaa catgcacaaa tcgttgagaa attggaaaac aaattggctc
   100981 cagctgatac aatggaagat taacttcacg atgcagtagt tccttcccat taagaaagga
   101041 tcttgaaaat gaagattaca gaaaaagatt ttggccaagg ttatcacttg ataaccttgg
   101101 agaacaaaaa caagctagca ctttctatct ctgatttagg tgctagaatc gtcagtttaa
   101161 aatcaaatga tcgagaatta gttttgggat ttgacaccgc tgaagaatat atcgaaaaag
   101221 atccgtatat cggtgcttct atcggtcgca ccgcagggag aatcgaaaat ggccgctttt
   101281 ctctcaatgg aaaaacttac caattagcca cagatccaaa aactggacat aatctgcatg
   101341 gtggtgctcc tggatttgaa ttaaaaaaat ggtcttatgt cattttgaat ggcgaaaatg
   101401 aagcttctgt catttttact actacaagtc ccgacggaga acatggtttt ccaggtacaa
   101461 tggatgtgga aatccgctat actttgacaa aagataatat ctggcgagtg acctctcgcg
   101521 gcaccagtga ccaagatact ttattcaatc cgacaaatca tgtttacttc aacttgacgg
   101581 gagatgcttc tcagtcaatc gatcaacatg agctttggct caatagcgaa gcttatgctc
   101641 ctttgcgaac agatagtatt cctatagggg taaaagaaaa tgctgcagga agtgctttcg
   101701 attttcaaat acctaaaaaa ttagcgtccg tttttgctag tgatttggat caaaaaaatc
   101761 ttgttgacgg aatcgatcat ccatttttct taaaagaaac cggcttgggt aaagaagccg
   101821 ctcgcttgac tagccccgat aaaagaatcc aagtagatat tgctacagat gcttctagtg
   101881 tggttatttt cactgcaaat ttcggcacag aaacaccaga aatgcgcaac cgaaaactgg
   101941 cacatcacgg tggcatcaca tttgagactc aaacagctcc aggtgcagag cgcttctcag
   102001 catttggttc gattcattta aaagccggat cagtatttga aacagtaaca gaattcaaaa
   102061 tcaaaacaag aaaggaataa ctcatcatgg aaatcaaaag aagcttaaac acaaaatttg
   102121 ccgaaacatt cggacctaaa aaaactacac aatacttctc accaggacgc atcaatttga
   102181 ttggtgaaca cacagattac aatggaggcc atgtcttccc cgcttccatc acttatggaa
   102241 cgcaaggtgt agcagcacct cgagacgata ataaaatatt agtttattcc acaaactttg
   102301 acgatatcgg tgtcattagt tttactttag atgagctaga atatgataaa aaagcaaact
   102361 gggcaaatta cgtaaaagga atggtcctta aattaaaaga agctggacac tcaatcgatc
   102421 atgggtttga gttattagtg gaaggaacaa tccctaatgg tgcaggactt tccagtagcg
   102481 cttcattaga attattagta ggtgttgtat tagaagatct gtttgattta aaaacagatc
   102541 gcttggaact agtccaaaca ggtaaaaaag tagaaaatga attcatcggt gtcaattcag
   102601 gtatcatgga tcagtttgcc atcggcttcg gtgagctaga tcatgcaatc ttattagata
   102661 caaatacgct gaaatacgaa atggttccag tgaaactaga tggttatgca atcgtcatca
   102721 tgaatacgaa taagcggcgg gaattggcag attcaaaata caatgaacgc cgtagcgaat
   102781 gcgaagaagc cttggcacgt ttgcaaaaaa ctttgcctat ctcttcttta ggagacttag
   102841 atgaagaaga atttgaatca actattgacc aaatcggcga tgatacattg atacgcagag
   102901 ctcgccatgc cgtttctgaa aatcagcgga ctttgaaggc aaaagctgaa ttagaagctg
   102961 ggaacttaga agcatttggt caactgttaa atgattctca ccactctctt cgctatgatt
   103021 atgaagtaac tgggatcgaa ttagatacac tagtagatgc tgctcaaaaa caagaaggtg
   103081 tcttaggtgc acgaatgaca ggagctggat ttggtggctg tgcgattgct cttgtcaaag
   103141 aagaaaatat acctgccttc aaaaacaatg tctatgatga atacatgaaa gttgtcggct
   103201 atgctccgga attttatgtt gcacacattg gaaatgggac aacaaagatc gatccagaag
   103261 ctgttcatgt ttgataaaaa aatcaacgat ctcagctaaa aacaaataga taaaaataac
   103321 ctctcagcaa tttccaaatg tgagcctttt gctcgtattt gaaaattgct gttttttatt
   103381 gacacggaaa gagaacgtgt gttctaattg tgttgaagag gtgattgtta tgtgggcgaa
   103441 tcaaaatccg gtatttgttt atgaaaaaga accttcaaga gatattttat gtattgactg
   103501 caaatctttt tacgcctccg tagagtgcgt tgaaaaggat cttgatcccc ttacaactaa
   103561 attagtagtc atgtcctatc cgtccgattc gacagaaaca cggggtagcg gattaatctt
   103621 ggcttccagt cctgcagcaa aaaaagctta cggcatcacc aatatcagcc gtgccagaga
   103681 tcttcccttc ccctatccaa gtgatttata tattgttgcc ccaaggatgg cctattatat
   103741 ggaaaagaac agagaaatca attctatcta taaaaaatat gcagacgaag cgaaccatca
   103801 tgtctattcc gtcgatgaaa gcttccttga tgtaacaaat agcatggcac tctttggtaa
   103861 aacaaatgcg tacgacatgg ctaaactgat ccataaagat gtgtttgagc agaccggaat
   103921 ctacacgact ataggaattg gcgataaccc gctacttgct aaactagcct tagacaatgg
   103981 ctcaaaagac ggaaagcaaa tgtttgctga atggcgttat gaagatgtac cagaaaagtt
   104041 atggaaaatc tcagatatca ctgacttttg gggaatcggc aaacgaacag caaaacgtct
   104101 gaaacaaatg ggtatacatt ctgtttatga tttagctcac gcggattatt atcacttgaa
   104161 aagcaagcta ggggtcatcg gtactcagct ttatgcccat gcttggggca tcgatcgaag
   104221 ttttttggga caagaatata caccaaaatc aaaaagtatc ggaaatagtc aaatcctaga
   104281 tagagattat acaagacgag aagaaatcga gatcgttatc aaagaaatgg ccgaccaagt
   104341 cggcactcgc ttgagacgat ctgcagcaaa aacacaagta gtcagcttat gggtaggata
   104401 ctctttaggc tatcttgatc caaatggcaa gaccgggttt caccagcaaa tgaaaatcga
   104461 agcgacaaat gctagcagag atcttgcaga tgctttattg accattttcc accagcatta
   104521 ccactaccag gatattcggc gtgtaggcgt gaactgttcc gacctcgtat acgcgacagg
   104581 tttacagctt aacctttttg aagatcctga aaagcagata aatgaagcga aagttgattt
   104641 tgttgtcgat acgattagaa aaaaatacgg ctttcaatca atcatccatg cgcatagtct
   104701 cttgcaagga ggacgcgcca tcgcacgtag ttctctcgtt ggcgggcatg caggtggtat
   104761 gagtggatta gaaggtggaa aagatgagac ggacagcaaa aaaattcatt gactataacg
   104821 agtatcgaga tcggccattt ggattaaaat gggggactgc ttttgcgatg gaagaactag
   104881 tcaacggtat caaaaaaatg aagaagaagc acgcaaacag cctcttccta aacaacaaat
   104941 gacattgcaa gaaatcgata gtatactgac agaagccttt ttatctcgta aagcagtaat
   105001 cattcagctc aatttaaaag atgaatttgg aagactcttg gatgaggtcg aagggcactt
   105061 cattggtgaa gcctatgaag attactttat gattgaccat cagccgatat tgtgggaaga
   105121 cgtacggtat attgagttaa aggaaacaaa aaaatggttt gtgacatgag aggttgtgac
   105181 agaagtgatc aacttcaaaa aataagaaag gatttttcga aaattgcttc ttaaattttt
   105241 gtggaatttt ggcttatttt tcgaagaagc aacttctgga acaacgtata ttagatatca
   105301 gaggttgtga aaaagtcgct tagttttgag taacaagcca aggcgctgat ttcacaacct
   105361 ctgtctatct atccatctat tcggtaagat tcatgcatga cgtcttcttt atttagtatg
   105421 tagagccctt tttcttctga ccattcaaca taaatcagct gttttacatc tgcatagcct
   105481 tctttcttca agttctccat aagccatgct tcagtcaatt gattggactg aagcacttta
   105541 tgctgaattt gcccttcatc tacaagcagg atcgataaag ctttgtcttc atctgatttt
   105601 ttcaatacac tcatttgacc ggcattctct aggataacat gtttggcatt ttcaagaaaa
   105661 aagcattctt gctgtcttaa gattgctcgc aactgctcca tctcgatatg gttatttgtc
   105721 aactctgtca tgttgatgac gccgtctttg attagaacag atggctcgcc tttgacccaa
   105781 cgattgacct tttcattttt ttggacgata cgttcgatac cataaatcat tactgcccaa
   105841 agcgcaatgg caaataggac atgccctaca tggacattgt catcataggt tgattcttct
   105901 aagatcccac ctaaaacaag cgtatagact aaatcaaacg gtgtgatttc tgacatggat
   105961 ttcttcccaa gcaaacgtac cactaataat aaaccgatca acccgaacac cagtttcatt
   106021 gtaattgaaa aaatcatttt ttctccccct aactatctgt taattaaatt atatatgctt
   106081 tctcacgaac acgcatggaa tatacaagga agaaatgtat ccttttacta aaaaaaggac
   106141 tgtgacactg tagtgacccc caaaagttag acttttttgg agtggagaaa tccactcctt
   106201 ttttttatgc tctaaaatga tatttttaca caaccgttac ggttgtttta cgaaattgga
   106261 cgagactttg ccagtttaat ttctgtttta tccgttcatt attgtagtaa tagatatagc
   106321 tatcgatggc tgattttaat tcctcgaaac agttataaac tttcccgtga aaaatctctt
   106381 gttttaataa gccaaaaaaa ttctccataa gtgaattatc taagcagttc cctttccgag
   106441 acatgctttg aaagattttg tactccttca atttgtttct ataagctttc atttgatacg
   106501 cccaaccttg atctgagtga aacgtacgac gatagggaca atcgttagtg gtctggatag
   106561 cttcctccaa accttccatt accgctaatg cattgggctt ttcagagata cgataggata
   106621 aaatctcact attgaacata tccataaaag gatctagata caatttcttt tgacggataa
   106681 tgcctttggc atccacttca tggtatttaa attcagttgt atccgtcgtg attttctgat
   106741 ggcagatact ggtgtagaaa cgacgatgga tccgattttt ggctactgct ccaacttttc
   106801 ctcgataaga attgtagcga cgtgatttac gcgtgtatgc cgttactttt attcctagct
   106861 tcttgatcaa gcgctgaact ttctttttat tgatagagaa accgcggttt cttagttcat
   106921 tggtcatccg taaacagcca taatccttgt gcttctcccg aattttaagc atttccgctt
   106981 caatctcttg atctggattt ttacggtcca atcgcctttg ccatccaaat aatcatgaac
   107041 gatctttaat ttaagttcaa aagtatattt aaccataaaa aataccgacc tccaaaagtt
   107101 agattttttg gtctaacttt tgggggtcgg tacacaaatc gtgtcacagt cccttttttg
   107161 aaaataaacg gtgttcaaaa gcttgcatct gcggtaataa gtccagccaa gttaaaaaca
   107221 taagaagctg tttttacttg gctgttctta ttacttgatg caaggcagct ttttcacaac
   107281 ctcttttcaa atatttcgtt ttcttattct acaaatggtt cttctcctaa cgcttgttga
   107341 gcggctagat tcaacatgct ccattgtcgg tcaaagcctg gctggaagaa gaagtcagct
   107401 tctgctagtt cttctaaagt cagtttgttt tggatcgcta gtgccaatac atttccttga
   107461 cctgtaacat cataggtaga taatactgct cctcctagca attgatgggt cattggatcc
   107521 gagaataatt ggatggacac ttttggattt ccttgttctt ctggtacata ttttggtcgt
   107581 aacgtatctt cataataaga cactcgtaca tctactcctg cttttgctgc tgtaaagcta
   107641 ttcaatccgc ttgctgcaaa atgatagtca aagacactta atgcagagga acctacgact
   107701 ccgccgaacg gtttgtttgg tacttcttca aaaagatgtt ttactacata acgtgcttct
   107761 ctacgtgcaa cagtcgctaa agcgatcggc atttttttgc gtgctgggat agaataagca
   107821 agtgtagcat ctcctactgc atacacatct ggaagattcg tttgcaagta ttcatttgtt
   107881 tggatccagc cacgttcatc taagtcgacg atccctttta accattctgt atttgccttc
   107941 acaccggcag cttgaatgac tagatctgct gggatttctt tttcacttgt tttgattgcc
   108001 tcaacttttc cgttaccagt aaaagcttcg atttttgcat ttgtcaaaac ttcaataccg
   108061 ttttcattta ggtgttgttc taaaatatct gtcatctcag catctaaata agtgcctaaa
   108121 ggtctatcga tcacatcaag caatacgact tctttcccag cttttcggct tgcttctgct
   108181 gcttcgatcc caatgtaacc cgcacctacg acagcgattt ttttaatagc cggatcattt
   108241 aatttttctt tgattttggt tgcccaattg tatccacgca tcaagtagac attttctaga
   108301 tctgctcctg gtactggcag attgtttggt ttgacaccag aactcaaaat caatttgtca
   108361 taaggatatt cttttgtttc gttatctgat gcgctagtaa ccgttactgt ttttttatcg
   108421 gcatcgatcg tttttacttc gtgattattt aaaatatgaa cattggattg cggaaagttt
   108481 tctggtctga aattacgtac atcatttaca tctgttacct tgtcttctaa atacagctcc
   108541 ataccacatg acatgaagga aatatagtct cctgcttcaa atagcgtgat atctacattt
   108601 tcaccgtatc gtgtcaatag ttccaagatc gattgatgcc ctccatgaga tgcacctaca
   108661 atgacaactt tgattttttc cattgatgaa acctccttga atattctttt aaaatcattc
   108721 taaacaattt aaacttaaca ttacattagt tatgaatcaa aagaaacgcg ttcatttgaa
   108781 ctaaatttaa aaaacaatcg tctccttgca gaatataccg caaaattaac gattgttttt
   108841 ttgataaaat ctatgaatca ctgttctgtt aaaaagtctt tgatccgttt gcaggcctca
   108901 tgtaattttt ccatgctgct agcataagaa atccggatat aaccttctcc ttctgggcca
   108961 aatgcaattc ctgggataca cgcaactttt gcctgttccg ctaattctac acaaaactgc
   109021 caagagtcag tttgaatggc agctgggagt ttgcaaaaca agtaaaatgc accgtttggc
   109081 tgggtcactt caaatcctaa aggcgccaat tgctggacca gatagtctct tcgtgtttga
   109141 tattgctctt tcatattctc gctatctttc accccattta ttagcgcttc agccgcagct
   109201 ttttgcgaca tcgttgtagc ggcagtcacc agatattgat ggactttaat tagttcgtca
   109261 ataagggctt tttgagcaaa aataaagccc actcgccaac cagtcatcgc atgtgacttg
   109321 gataacccgc ttatcacgat tgtttgttct ggaagataag tagctatgga catatgcgtt
   109381 ccactataag tcaattcagc atatacttca tcacttataa caaataccgg atattttttt
   109441 aaaacctcag cgattgcttt caattgtttt gcagacaatg tcgtcccagt aggattgtta
   109501 ggatagttta aaatgactgc tttgacagct gatccatatt gttcaaatgc tcgttcaaat
   109561 tgttccggct gacagacaaa ccctgtgtca gaagtatcta tcgggatcaa ttcagcacca
   109621 gctagttcca ctaatggctg atatcctgaa taagcaggcg ctggaataag aaccttgtct
   109681 ccttcttcca aaacagataa caacgcagag gcaatcgctt ccgttgcacc aactgtcgtc
   109741 aaaacttccg tttgcggatc ataagttaat ccataacgct gttgctgaaa tatacaagcc
   109801 gcttcccgca gttcctctaa tcctctcatt ccggtatagt gagaaaagtc ttcttcaatc
   109861 gctgctattc ctgcttgctt gacatgttca ggagttggaa aatccggttc tcccagggtg
   109921 agtttgatca catctggtat cgacgatatt tgctgatcga attgtcgtat ttttgatact
   109981 tctattctag aaagcctagg actaaatcga ttggataaat tcatcattat ttactcgctc
   110041 ctcttttgaa ctgctatcga tttttacaag aagattttct gtaaaaagaa tcgttttgta
   110101 ccattctaca ccattttcta aaacatccat atcaaaatcg aacgtcggat catgtaaagc
   110161 aggggtatca ccgacaccta aaaagaaaaa tacacatgga tattgttgcg tatatatgcc
   110221 aaaatcttcg gcttgaagaa ctggagcatc taattcatgt agtttgtttg aatctaacag
   110281 tgctgcatat aagcctctat ggttgattac agctggatag ccgtcattat agcgaaaaga
   110341 aatagtagct gtagagtgaa actgttctgc taaatggtct aatcccctct tcaaataatt
   110401 ttgcatatct gaactgtaag aacggatact tccggataca ataacttctc cagctaaaac
   110461 atttcggatc gttccacctt ggatttggcc aaatttcatt agatgattcc actctgccgg
   110521 taattgccgg tcaaaatcat aaacattctt caaaaatcgt acagctgcct ccagactatc
   110581 gattcctttt tcactagaag caatatgtgc agactggcct ttaatgataa tgtctgtttc
   110641 actgctttgt gccatcaaag gtcctggtcg agagaaaact tctcccttag ctagtccagg
   110701 ccatagatga aagccaaata ttgcttgtac ttcatattta tccaacaatc ctgactgaat
   110761 aacgctttgt gcgccaccgg aaatttcttc tgatggctga tagatcagta ctacattata
   110821 aataagatcc tcaatgtgtt tagttataaa gtcagtcaac cctaaaagca tcgccatatg
   110881 tccgtcatga ccacatgcat gcatataacc ttcatgctta gaagcaaaag agagattcgt
   110941 ttcttctttg actggcagtg catcgatatc tgttcgaaaa gcaatcgttt cttcttgctg
   111001 attatcaaaa taaaggagta gtcctgtttc gccgatttca tggataacgg cctcgctgtt
   111061 ttttacttgt tcatataaat atttttttgt cttgaattca tgaaacccga tttcaggaat
   111121 ttgatggagt gccattcgat attctttcag catccgtatt caccatccct tcatagatac
   111181 ccttcactac tgtttcatat tgattattcg gtacaccgat gatcagattc aactcctgtg
   111241 ctccttgtga taagatcgat gtgcgaattt ctaatttgtt caatatcgat aacactttcc
   111301 cagataatcc aatcaattct ttatgcggac ccccaacgac agagatcaaa gctaagtctt
   111361 cgatcacgac gatttcttcc acgccaagtg tttcttttaa ttctttcgtg atgagaaata
   111421 acttatcggc aatcgcttct gctgagacga tcactccgat attgtcgatc cctgaaggaa
   111481 tatgttcgat tgatatctca tgtttagcaa aaatgctcat tgctttccag ataaacccga
   111541 tttcatcgga catatgacgt ttgaataaag tgatggaaag aaaatccttg cgtccagcta
   111601 ttcctgtcag tccattttcc ttttctattt cgtgattcga tatttttgtc ccttgagcga
   111661 aaggatcatt ggtatttttt atttggatgg ggatatcagc ctcttgaact gggaaaacag
   111721 ctgcttcatg aagaacgtta gcccccatat aagccatctc tctcagttct ctaaaagaga
   111781 tttcctcgat gattttagga tgatcgatga ttcgcggatc agccatcatg attcctgaaa
   111841 catccgtcca attctcataa ctttccgctt gcaacatctt cgccagtatc gcgccggtaa
   111901 tgtcgcttcc cccacggccc aataattttt cttttcctgc agggttcgcc ccgtaaaacc
   111961 ctggaacaac cattttcgga tatcttttaa atgcttttgt gatttcctgt gctgtttttt
   112021 cctgatcgat tttcccatca tagtcaaaga aaatcaggtc ttttgcgtca ataaactggt
   112081 aaccaagata ctcagccatc agttgagcag tcagatattc acctctactt actaaataat
   112141 cttcagttat cttttcgtct tccagttgtt tctgtatgcg tgctagttca tcttcaatag
   112201 gtaactgcag ggcaagaaca tctcttactt gaatgaaacg atcacaaatc cttttccaaa
   112261 ggggtgtcca atcaacatga tgctgaaggt aagcataaat caaataaagt aagtctgtta
   112321 ctttgtcatc atctgacgta cgtttgccta aagcagaaac aacgatcact tggcgattgg
   112381 gatctgaaag aacaattgta cggacttttt tgaattgctc ttcatgagac atcgatgttc
   112441 cgccgaattt cgctactttc agcgtattac tcatcttgcc acctccgcta ttttctgcat
   112501 taaagctgca gcaatctgta cggcattcgc agcggctcct ttgcgtatgt tatcggcagt
   112561 cgtatagaac aacaatccgt tctctaaaga agtgtctttt ctgatcctcc caacataaac
   112621 catatctgtt cctctagcaa gaatgctcgt cggatattta tgtgctgcta gatcatcttc
   112681 taattgaatc cctggaaact ggctgagaca ctctctaatt tcttccgtcg taaactcttt
   112741 ttgcagttga actgccacag agactccatg tccattttcg attggcacac gtacgcaggt
   112801 tgctgatact ggcaaagcag gctgatgcag aatcttacgg gtctcattta tcattttctg
   112861 ttcttctttt gtatacccat tttccaaagg ctgatcgatt tccggaatca ccgtttggct
   112921 aatattataa ggatacaaaa ctggttcctc gtcattttgc gtacgatgaa gatcttcaat
   112981 gcctttttgc ccggaaccag aaactgcttg ataggtcgaa taattgactc gctggatacc
   113041 aaaggcttct tgtaaagctt taagcggaag taccgcttga atggttgaac aatttggatt
   113101 tgcaatcagc cgattcaatg tatagtcttc cagattgacc tctggaacga ttaatggaat
   113161 atccgaatct tcccgccatg ctgaggaatt atctatgaca aatagtccct gacttcgtgc
   113221 gattggcgca aactctttgg atacagaagc acctgcagaa aatagcgcta aatcatatcc
   113281 ttcaaatgaa gtttctgtca attcctgtac agtgtgtttc tttttcttga atacacaaac
   113341 tttaccggct gaacgttttg aagctaataa tttcaatcgt cctactggaa aatcatattc
   113401 ttctaacact ttgagcatcg tttggccgac taatccggtt gcccccacaa tacaggtatc
   113461 tatttcgcgc atttttctcc atctcctcta taattcgcgt aacgcagcaa tcaatgctgt
   113521 attttctttt gtctgatcat cacttatttt taatacacgt gcaggtattc caccgacaac
   113581 agtttctgct gccacatctt ctaaaaccac tgctcctgct gccacgactg catcttttcc
   113641 gatatggaca ccttcaacaa tcactgcatt cgcacctacc agtacgccgt cttctacgat
   113701 aaccggtttg gccgatgctg gttcgatcac acctgctaag acagctcctg caccaatatg
   113761 gcagtttttg cccactgtcg ctcgtccacc taagacagca cccatatcaa tcatcgtgtt
   113821 ttcaccgatt actgcaccaa tattgataat cgctcccatc atgatcacgg cattgttgcc
   113881 gattgacact tgatctctga taatagcacc tggttcgata cgagcattaa tttttttaat
   113941 atctagcaaa ggaactgcgc tgtatcttgc agcagtttcg atttcgattt caatgatttt
   114001 ttctgattca gcttctaaaa ccggagcaat cgtctcatag tcaccaaaaa caacgaagct
   114061 gcttccttca ccaaaaactt tactttcttt aaattcgatt ggctcggtta cattcagata
   114121 gactttcaca ggcgtctttt tagatgccgt ttgaatgtag cggatgattt cttgagcttc
   114181 cacgtttttt acaccccttt gtccattaat aaatcttcta atttgtaata acctggtgac
   114241 tgatctttca accagtccgc tgcttctact gcgcctgcag caaagattcg attagaaaaa
   114301 gattcatgtt tgatcgtaaa tatttcatca gtagcagcaa acaatacatc atgttcacca
   114361 ggtaaagaac ctgcacgaat actgtgtaca ccaatttggt tttcttctct ttttttccct
   114421 tgccagttgt atacgggctg cagcttttgc acttcttgga ttgtttgaag cagcatattt
   114481 gcagtaccag atggtgcatc ttttttacga ctatgatgtt tttcaatcag ttcgatctgc
   114541 cagccttgca acattgcagc tgcttgcttg attagttgat tcatcaccat gatgccgaac
   114601 gaaaaattag cactatacat cacaggtaca tgtttggcat gttcttttat ttcttggaac
   114661 tgtgattgtg tataacctgt cgtgccaatg actaacggaa gttgatatga taagctatac
   114721 gaaaggattt tctctaaatt atctggatga gaaaaatcaa taagcagttc tggcagttcc
   114781 gtaaaagcaa gcgtagttgc ttctttaggt gccgtccgta aaagaaggac cgtatctcct
   114841 ctttcttgtg caacttcttc gactctattt cccatctgtc cactgccaat cagtccgatt
   114901 ttcatttttc aaccgtcctt tcttttaaca aaagctgagc taattgtttc tttttctctt
   114961 ttgaaagaga aactaaaggc aggcgtagag gtccggaagg taagtctaat aatgacatgg
   115021 ctgctttgac aggaatagga ttggtctcac tgaacaaggc atggatcagt tcaagtgcat
   115081 ttaattgctt ttcttttgct tgctgccatc ttccgtcctg cgtatctttt actaattcat
   115141 ggactatttt aggttggata ttcgcccata cacttattac accgcttcct cctacactca
   115201 ttactggtag gatcaaatca tcatttccac tgtaaaggaa gaattcttct ccaatcaacc
   115261 gagcggcatc catcacataa gccatatctc ctgaggcttc tttcaaacca atgatattag
   115321 gatgttctgc taaatttact aatacatgga ttggaatcga catgcctgtt ctagaaggaa
   115381 cattatacaa aataagcgga atcggtgagg cttctgcaat tgctgtaaaa tgagcagcta
   115441 gtcctgcatc acttgttttg ttgtagtaag gggtgatgac caaaagtgcg tctgccccca
   115501 aagaagcaaa atgcttcgct ttttcaatcg tttctttcgt attattcgtt ccagctcctg
   115561 caatcaccgg cacacggcca gccactttct ttactgtcag ttgaaggatc tgctcctcct
   115621 cagattgtgt gagcgtagaa gattctcctg ttgtacctaa aactaataat ccatctgttt
   115681 gttcatctaa atggaattgg atcaattttt ccaaaccagc ataatctact gatccctctt
   115741 cattcatcgg cgtgatcagc gccacgatcg aaccttttat catcttcatt cctccaatat
   115801 tcttgtccat tcatgaactg ctgggccagc catttgtatc gcatcctcac cagagatcat
   115861 caagtctcct tgttccaagt gaacaactac ctgatctgct gaaattttcc cagtttcctt
   115921 agcaaccaca taagaggcac agcaacctgt accgcaagca agtgtccaac ctactcctct
   115981 ttcataggta cggacgatca attcttgttc attgactact tctacaaagt tgacattggt
   116041 tttttctttg aacaaaggat gatgacagat cagttcacct ctttttctcc agacttcctc
   116101 acgcgcattt tcaacaaaaa caacggtatg aatcgttcct aaaaataaac tagtgatcgt
   116161 tactttttca ccattgatct ctatttcctg gttttttatt ggataagttt gattagcttt
   116221 gattttttcc ggagaatcat ctggcactcc catatctacg ctgcaataaa aaggtgaggg
   116281 atccaacacc gtaatttttc ttgtgcctgc taatgtctct acgttgaatt cctgttcatt
   116341 catcatgttc tgatcattta cgtatcgagc aaaacagcga atgccatttc cgcacatcgg
   116401 cgcgcggctg ccatctttgt tgtaatagat catttccaac ggatcgattt ttacggcgat
   116461 caatccgtct atatcatatt tttcttttgt gcataaagaa gcggctaatt gactataatc
   116521 tgtgtcttct gcgtaatcta ataagataaa atcatttccg cagccattat atttatgaag
   116581 gatcatagga aacttccccc cttagtagat cagaaaatgc ttgtctgcga acaatcagtc
   116641 ttgattggcc attattgaca aaaacaactg ctggtcgtgt cgctcgattg tagttgctgc
   116701 tcatcgagta tccataagct cccgtggaat aaacagctaa aagatcaccc gattctgctt
   116761 tcggcaaata agcttcttta attaccacat cgcctgattc acacattttt cctgcaatcg
   116821 tcactttctc tgttttttct tccgacagtt ttgctgctaa atcacaatcg tattctgcct
   116881 gatacagagc tggacggata ttatctgtca tcccgccatc tacaaagtaa tattttttat
   116941 gtggtgtctt tttgatgaaa ccaatcgtgt atagtgttgt accagcttct ccaacaatac
   117001 ttctacccgg ttcgatcagt aattgacgaa tggtcagttt tcgtttttcc aaagcttctt
   117061 ccgtatattc aatcagtttt tttagtgcct cttcgactgg gatcggctga tcattttgtg
   117121 tataacgaat cccaaaccct ccgccaagat tcaaggaaag aggttggtca aaatcggtta
   117181 agtaattcgt caatttgtcg atttcagcta accaagcagt aacatcaaaa atttgtgacc
   117241 cgatatgagc atgaaatcct tctaactcta gatagctgct ttcttttatc aactgaaggg
   117301 cttgttggca ctctttactt tcatagctca tgccgaattt tgaatcaata tgcgcagtga
   117361 cgatatattc atgagtatgt gcttctactc cgacattcaa ccgaagcatg atacagattt
   117421 tttttaaata gcgttggctt aattctgcta ataattcaac ttccatcaaa ttatcggcaa
   117481 caatatgcaa caaatcattt tcaagtgcat agatcagttc ctctggcgtc ttgttgttac
   117541 catggaagta gatagtatct ctaggaaaat cagcttgcaa agcggtatag atttccccac
   117601 cactgacaac atctagcccg aatccatatt cacgaactaa atgcagcatc tcaatcgttt
   117661 ggaatgcttt agaggcgtaa agcacttttg tatcaaaacg tttcgataca aagcctcgct
   117721 tgaatgacag catcgtttgt ctcatctttt cttcatcata cacatacaga ggtgtcttat
   117781 acttttctgc caatgtgctt gctgtgactc cgccaattat caattctgtc attttttcat
   117841 tcctcttttc actttttttc cgtttttatt ggaatttcat ttgataaaga tttgaatttt
   117901 attggaataa tattaaacaa aattttctga attgtctagt atatttcgaa atattttttt
   117961 aaaaataaga ataaaaatgg ttataaaaac aaaatacccg aactattaga agctatttat
   118021 acataaaaac ataaattcaa cactatttag tgatgaaaaa atattttcgc ttcaatatag
   118081 ttcggaatag ttcggatatt ttcaatttta tgaatcattt caatttcttc ataaataagt
   118141 gcagtttttt ctttctctag cttttgccat tcatctttca aaatataaat aaaatcaaat
   118201 acttttttat ttttcaattt gctgattcca caaaaaacct cttgaaaggc agatccgatg
   118261 atctgccttt caagaggtca agctctgttt tcaaattctt atcaatccgt tagcgaatta
   118321 ttttgacgca cgttttacat aagaaccttc tgctgtattg atttccaaca attcatctgt
   118381 ttcgatgaag tcaggaacat tgactactaa gccagtttcc attgtcgctg gcttacctga
   118441 accagtgact gttgcacctt tgatggaagg ttgtgtttcc acaacacgta atacgacagt
   118501 tgttggtaat tgaacgccga tgacttcgct accgaaaaat tggattttta cttccatgtt
   118561 ttctaggata tatttcattt cttcttctac tgtttctaca ggaatttcat attgctcata
   118621 tgtttccaaa tccatgaaga aagctgtatc atccatcgtg tacaaatatt gtacaggttt
   118681 tgtgtcgata tgtgcttttt caaatttttc ttctggtctg aacgttgtgt cgtatgttgc
   118741 acctgaacgg acatctttca gtttcatacg cataactgta tttcctttac caggtttatg
   118801 gtggcttgca tccagaactt taatcagttt gccgtcttgt acgaaagtca taccggctct
   118861 taaatcactt gctgagatca ttatttttgc tccttctttt ctttatcata atcaacttta
   118921 ttgtatcaga caaccggcca gaaaactaga gtattctcta tcttttaagg tctcatgcct
   118981 atttgtcaga aaaataaaca cgggtaaacg atgctatcga aatatttttt tctttcaagc
   119041 ctttgacttt tatttttttt catgctatcg ttaataaaaa ttttacttgg agggatacac
   119101 atgacagtca gcaaccaaaa acaattgaat cgttgctgtt gtatggtgca taaaagcagc
   119161 atactatttg tcatgtctat taattgccct tcatagaatg agtaccaggt aacttatctt
   119221 tttatctact caatttttct ctatgtcttt caaggagctg atttaatagt cagctccttt
   119281 ttttattatc tttttttagg aggcccacat gattatctcg acaattacag aagctattgg
   119341 ttccacaccg ctttatcgct ttgacaatca gcactattct atgcctaaag gttctgctat
   119401 ttatgcaaaa ctagaatatt taaatcctgg aggaagtatc aaagatagat tgggcagtta
   119461 tttgatcaaa gaaggatttg cccaaggaaa aatcaatgaa aaaacgacga tcatcgaacc
   119521 aactgccgga aatacaggaa ttgggatcgc tctggccgca ctcacataca aattaagaac
   119581 ggtttttgtt gttccagaga agtttagctt agaaaaacaa caattgatga aagcattggg
   119641 agcaaagatc atccattctc ctagtgagca aggaatcatc ggtgccatca gcaaaagtaa
   119701 aaaacttgca gaggagatat caaacagcta tctgcctctt caatttgaaa ataaagataa
   119761 tcctgctgct tactatcata cgttagggcc agaaatcttt catgaaatca aagaaaatat
   119821 ccatagtttt gtagcaggaa ttgggagtgg tggaaccttt gctggaactt ctaccttttt
   119881 gaaagaaaaa tatcccgaca ttcgaataat cggtgtagaa ccagagggct ctgtgttaaa
   119941 tggtggtgat ccagcccctc acgaaattga gggtatcggt gtagaattca ttccgccgtt
   120001 tctttctccc ctttcaatca atcagatcga gacaatctct gatgtagaag ggtttaacta
   120061 tactaggcag ttagcacgag aacaaggact attagttgga agttcgagtg gtgcggcttt
   120121 tgcagcagca ttaagagaaa ttcgtcgttt accacctggt catcgtgtcg ttacgatttt
   120181 tccagacgca gcagaccgct atttatcaaa aaacatttac ttataggagg aaagaaacat
   120241 gcacattcaa acaaaattga tccacggagg catcagtgaa gatcccacaa caggagctgt
   120301 cagtgtacct atttatcaaa catccactta tcggcaagat ggcgtcggcc agcctaaaca
   120361 atatgaatat tcaagatctg gtaatcctac tcgttttgca ttggaagaac tgattgctga
   120421 tttggaaggc ggtgttcgag gattcgcttt ttcttctggt ctttctggga ttcatgccgt
   120481 tttttctctt tttcaagctg gcgatcatat cttattagga gatgatgtct atggaggaac
   120541 attccgtcta tttgacaaag ttcttactaa aaatggtctc gagtacacga tcatagatac
   120601 gagtaatctt gataaaatag aacaatccat caaacccaat acaaaagcac tttatcttga
   120661 aacacctagc aatccgcttc taaagattac tgatttagaa aaaagtgcca ctctggctca
   120721 tcaacatgga ttgatagtta ttgctgacaa tacatttgct actccttatt ttcaaagacc
   120781 tttagatctc ggttctgata tcgttgtcca tagcggtacc aaatatctag gcggacacag
   120841 cgatgtagta gctggtttag tgacttctaa ccataaagat ctagccgatc agatcggatt
   120901 ttaccaaaat gctatcggag ccgtacttgg tccccaagat agctggttac ttcagcgcgg
   120961 aatcaagaca ctaagtgttc gtatggagga acatcaaaaa aatgcttttg tggtagctga
   121021 ttttctattt tctcatccag cagtagaaaa ggtctactat ccaggattac ccgatcatga
   121081 actccatgga gttgctaagc agcagatgag cggctttagc ggaatgattt cttttacttt
   121141 aaaaaatgaa gaatctgcta ttccatttgt tgaatcactc caactattta ctttagcaga
   121201 aagtttaggt ggcgtagaaa gtttagtgga aattccttct gtcatgactc atgcgtctat
   121261 tccaaaagaa aaacgagaag aggctggcat aaaggacggc ttgatccgtc tttctgtagg
   121321 aattgagtat ggtcaggatc tcataaacga tttagctcag gcatttgaca gaatcaagaa
   121381 ctagaagtcc caataaacga cttagcagaa aaatctaaaa aatatttcag attgctacac
   121441 cttggaaacg ataagtgtta gaatcaagta gaaagacgtt tttgtaaatt tcactaaata
   121501 attctttagt gaaaagcatc aaaacgaatg aacaaacaga taggagtctt acaaatgaga
   121561 atgaatgtcg aaagttttaa tcttgaccat acaaaagtca aagcacctta tgtacgtgta
   121621 gctgatcgaa aaacgggtgc gcatggcgat gtcatcatta aatacgacgt ccgctttaaa
   121681 caaccaaata aagaacacat ggacatgcca agtctacatt cacttgagca cttgactgcc
   121741 gaactaatcc gcaatcacgc agattacatc gtagactggt ctccaatggg atgccaaaca
   121801 ggcttttact tgactgtatt gaatcatgaa agctacgaag acattttaga tgttcttgaa
   121861 gcaacaatga aagatgttct tgaagctact gaagtacctg caagcaatga aacacaatgt
   121921 ggctgggctg ccagccatac actagaaggt gcacaagctt tggctcgtga atttttagca
   121981 aaacgcgatg aatggtctga agtagaagca tagtttctaa aagaacgtaa agatgagaag
   122041 caatatagct atcttatctt cgtattttat taaatattta ttgtctgaaa agagttctaa
   122101 acgggaaaac aaatagctag ttttcagttt agcgctcttt ttattatata aaatagaaag
   122161 gagaaaactt tatgtctatt tataattttg aaactacttt agaagacggc actgtctatt
   122221 cattgaaaaa atatgcaggc aaaccgataa tcattgttaa cactgcaaca aaatgcggtc
   122281 tagcacctca atttaaacaa ttagaagaac tttaccaagc ttatcagaca caaggtctgg
   122341 ttatcttagg ctttccttcc aatcaattta aacaagagct agattcagcg actgaagcag
   122401 cagaagcttg taaaaccact tatggcgtta ccttccctat gcatcaattg attgacgtaa
   122461 atggagaaaa tacagatcct ctttttactt atcttaaaaa tgaagctcct ggtactgtca
   122521 ctaaagcaat aaaatggaat tttactaaat ttttgattga tagaaatggc aaagtaatcg
   122581 aacgatttgc accacaaact tctccattga aaatgaccgc tgcaattgaa tccgttcttt
   122641 aacttaataa aaataaaaaa agatgaacta tttctagttc atctttttgc ctttgcgtgg
   122701 cgacgtccta ctctcacaag gggcaacccc tcactacaat cggcgctaag aagcttaact
   122761 tctgtgttcg gcatggttac aggtgtatcc ttctcgctat cgccaccaca ctgtggtgtt
   122821 atcttttatt gagtaaattt tgttcactca aaactgga
//
LOCUS       DAIGWC010000002        89992 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.002, whole genome shotgun sequence.
ACCESSION   DAIGWC010000002 DAIGWC010000000
VERSION     DAIGWC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 89992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.002"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(71..1492)
                     /locus_tag="NOB74_000119"
     CDS             complement(71..1492)
                     /locus_tag="NOB74_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1219334.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="NOB74_000120"
     CDS             complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="NOB74_000120"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCI1219335.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3903..5159)
                     /locus_tag="NOB74_000121"
     CDS             complement(3903..5159)
                     /locus_tag="NOB74_000121"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HCI1219336.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(5271..5476)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5739..7040
                     /locus_tag="NOB74_000122"
     CDS             5739..7040
                     /locus_tag="NOB74_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCI1219337.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7109..7708)
                     /locus_tag="NOB74_000123"
     CDS             complement(7109..7708)
                     /locus_tag="NOB74_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1219338.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7963..8844
                     /locus_tag="NOB74_000124"
     CDS             7963..8844
                     /locus_tag="NOB74_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1219339.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8857..10467
                     /locus_tag="NOB74_000125"
     CDS             8857..10467
                     /locus_tag="NOB74_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCI1219340.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10544..11203)
                     /locus_tag="NOB74_000126"
     CDS             complement(10544..11203)
                     /locus_tag="NOB74_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI1219341.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(11486..12151)
                     /locus_tag="NOB74_000127"
     CDS             complement(11486..12151)
                     /locus_tag="NOB74_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HCI1219342.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(12298..12903)
                     /gene="dhaL"
                     /locus_tag="NOB74_000128"
     CDS             complement(12298..12903)
                     /gene="dhaL"
                     /locus_tag="NOB74_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HCI1219343.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(12931..13941)
                     /gene="dhaK"
                     /locus_tag="NOB74_000129"
     CDS             complement(12931..13941)
                     /gene="dhaK"
                     /locus_tag="NOB74_000129"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HCI1219344.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(13916..14362)
                     /gene="dhaM"
                     /locus_tag="NOB74_000130"
     CDS             complement(13916..14362)
                     /gene="dhaM"
                     /locus_tag="NOB74_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HCI1219345.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            14465..14785
                     /locus_tag="NOB74_000131"
     CDS             14465..14785
                     /locus_tag="NOB74_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HCI1219346.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(14897..15766)
                     /locus_tag="NOB74_000132"
     CDS             complement(14897..15766)
                     /locus_tag="NOB74_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI1219347.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(15862..17166)
                     /locus_tag="NOB74_000133"
     CDS             complement(15862..17166)
                     /locus_tag="NOB74_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI1219348.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(17163..17672)
                     /locus_tag="NOB74_000134"
     CDS             complement(17163..17672)
                     /locus_tag="NOB74_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219349.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(17847..19859)
                     /locus_tag="NOB74_000135"
     CDS             complement(17847..19859)
                     /locus_tag="NOB74_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1219350.1"
                     /translation="MKEMAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAEN
                     QLAKIERLLKSPYFGKVVVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFY
                     NNMIGPSSYTVRQNKIDTVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETN
                     EMKAITATIQSEQNTIIRDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDD
                     LLILSPNHRFIDYISNVLPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENV
                     SEQTERLRSKKFIDNLKQSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPK
                     LIDRLQATKKALMSEWKNHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIV
                     AYARKLLQKKYRKITRQIEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILA
                     IRHLLVEKVNVPAFRYLLIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTT
                     FADIMRCFDDYHLPIHRYDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEY
                     RSFRSSEELLKILAEILVSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLS
                     LAKGLEFDHVILYPFENDGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(20064..21719)
                     /locus_tag="NOB74_000136"
     CDS             complement(20064..21719)
                     /locus_tag="NOB74_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI1219351.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(21721..22035)
                     /locus_tag="NOB74_000137"
     CDS             complement(21721..22035)
                     /locus_tag="NOB74_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI1219352.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            22205..22465
                     /locus_tag="NOB74_000138"
     CDS             22205..22465
                     /locus_tag="NOB74_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HCI1219353.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            22479..22793
                     /locus_tag="NOB74_000139"
     CDS             22479..22793
                     /locus_tag="NOB74_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HCI1219354.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(23523..24077)
                     /locus_tag="NOB74_000140"
     CDS             complement(23523..24077)
                     /locus_tag="NOB74_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HCI1219355.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(24203..26132)
                     /locus_tag="NOB74_000141"
                     /pseudo
     CDS             complement(24203..26132)
                     /locus_tag="NOB74_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(26438..27154)
                     /locus_tag="NOB74_000142"
     CDS             complement(26438..27154)
                     /locus_tag="NOB74_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCI1219356.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(27155..28978)
                     /gene="glpO"
                     /locus_tag="NOB74_000143"
     CDS             complement(27155..28978)
                     /gene="glpO"
                     /locus_tag="NOB74_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HCI1219357.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(28992..30488)
                     /gene="glpK"
                     /locus_tag="NOB74_000144"
     CDS             complement(28992..30488)
                     /gene="glpK"
                     /locus_tag="NOB74_000144"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HCI1219358.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(30624..32084)
                     /locus_tag="NOB74_000145"
     CDS             complement(30624..32084)
                     /locus_tag="NOB74_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1219359.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(32074..33369)
                     /locus_tag="NOB74_000146"
     CDS             complement(32074..33369)
                     /locus_tag="NOB74_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI1219360.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(33701..34378)
                     /locus_tag="NOB74_000147"
     CDS             complement(33701..34378)
                     /locus_tag="NOB74_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HCI1219361.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(34408..35499)
                     /locus_tag="NOB74_000148"
     CDS             complement(34408..35499)
                     /locus_tag="NOB74_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HCI1219362.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(35600..36034)
                     /locus_tag="NOB74_000149"
     CDS             complement(35600..36034)
                     /locus_tag="NOB74_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1219363.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(36618..38075)
                     /gene="ascB"
                     /locus_tag="NOB74_000150"
     CDS             complement(36618..38075)
                     /gene="ascB"
                     /locus_tag="NOB74_000150"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI1219364.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(38072..39967)
                     /locus_tag="NOB74_000151"
     CDS             complement(38072..39967)
                     /locus_tag="NOB74_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1219365.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(40025..41800)
                     /locus_tag="NOB74_000152"
     CDS             complement(40025..41800)
                     /locus_tag="NOB74_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCI1219366.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(41850..43346)
                     /locus_tag="NOB74_000153"
     CDS             complement(41850..43346)
                     /locus_tag="NOB74_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1219367.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(43540..45162)
                     /locus_tag="NOB74_000154"
     CDS             complement(43540..45162)
                     /locus_tag="NOB74_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCI1219368.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(45490..46803)
                     /locus_tag="NOB74_000155"
     CDS             complement(45490..46803)
                     /locus_tag="NOB74_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCI1219369.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(47048..47272)
                     /locus_tag="NOB74_000156"
     CDS             complement(47048..47272)
                     /locus_tag="NOB74_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219370.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(47292..47714)
                     /locus_tag="NOB74_000157"
     CDS             complement(47292..47714)
                     /locus_tag="NOB74_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HCI1219371.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(47856..48566)
                     /locus_tag="NOB74_000158"
     CDS             complement(47856..48566)
                     /locus_tag="NOB74_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219372.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(48584..49081)
                     /locus_tag="NOB74_000159"
     CDS             complement(48584..49081)
                     /locus_tag="NOB74_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1219373.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(49118..49570)
                     /locus_tag="NOB74_000160"
     CDS             complement(49118..49570)
                     /locus_tag="NOB74_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1219374.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(49705..50310)
                     /locus_tag="NOB74_000161"
     CDS             complement(49705..50310)
                     /locus_tag="NOB74_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI1219375.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(50760..51380)
                     /locus_tag="NOB74_000162"
     CDS             complement(50760..51380)
                     /locus_tag="NOB74_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HCI1219376.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(51382..52251)
                     /locus_tag="NOB74_000163"
     CDS             complement(51382..52251)
                     /locus_tag="NOB74_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HCI1219377.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(52274..52681)
                     /locus_tag="NOB74_000164"
     CDS             complement(52274..52681)
                     /locus_tag="NOB74_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCI1219378.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(52700..53989)
                     /locus_tag="NOB74_000165"
     CDS             complement(52700..53989)
                     /locus_tag="NOB74_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1219379.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(54016..54318)
                     /locus_tag="NOB74_000166"
     CDS             complement(54016..54318)
                     /locus_tag="NOB74_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1219380.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(54343..56436)
                     /locus_tag="NOB74_000167"
     CDS             complement(54343..56436)
                     /locus_tag="NOB74_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI1219381.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(56925..57689)
                     /locus_tag="NOB74_000168"
     CDS             complement(56925..57689)
                     /locus_tag="NOB74_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HCI1219382.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(57800..58669)
                     /gene="mdcB"
                     /locus_tag="NOB74_000169"
     CDS             complement(57800..58669)
                     /gene="mdcB"
                     /locus_tag="NOB74_000169"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HCI1219383.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(58694..59770)
                     /locus_tag="NOB74_000170"
     CDS             complement(58694..59770)
                     /locus_tag="NOB74_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HCI1219384.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(59794..60387)
                     /locus_tag="NOB74_000171"
     CDS             complement(59794..60387)
                     /locus_tag="NOB74_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HCI1219385.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(60391..62067)
                     /gene="mdcD"
                     /locus_tag="NOB74_000172"
     CDS             complement(60391..62067)
                     /gene="mdcD"
                     /locus_tag="NOB74_000172"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HCI1219386.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(62057..62356)
                     /locus_tag="NOB74_000173"
     CDS             complement(62057..62356)
                     /locus_tag="NOB74_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HCI1219387.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(62458..64104)
                     /gene="mdcA"
                     /locus_tag="NOB74_000174"
     CDS             complement(62458..64104)
                     /gene="mdcA"
                     /locus_tag="NOB74_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HCI1219388.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(64111..65022)
                     /locus_tag="NOB74_000175"
     CDS             complement(64111..65022)
                     /locus_tag="NOB74_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCI1219389.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            65142..65999
                     /locus_tag="NOB74_000176"
     CDS             65142..65999
                     /locus_tag="NOB74_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1219390.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(66186..66548)
                     /locus_tag="NOB74_000177"
     CDS             complement(66186..66548)
                     /locus_tag="NOB74_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HCI1219391.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            66894..68333
                     /locus_tag="NOB74_000178"
     CDS             66894..68333
                     /locus_tag="NOB74_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1219392.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(68340..70892)
                     /locus_tag="NOB74_000179"
     CDS             complement(68340..70892)
                     /locus_tag="NOB74_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HCI1219393.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(71006..72337)
                     /locus_tag="NOB74_000180"
     CDS             complement(71006..72337)
                     /locus_tag="NOB74_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1219394.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(72303..73781)
                     /locus_tag="NOB74_000181"
     CDS             complement(72303..73781)
                     /locus_tag="NOB74_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1219395.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(74086..75921)
                     /gene="tdc"
                     /locus_tag="NOB74_000182"
     CDS             complement(74086..75921)
                     /gene="tdc"
                     /locus_tag="NOB74_000182"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCI1219396.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            76391..77818
                     /locus_tag="NOB74_000183"
     CDS             76391..77818
                     /locus_tag="NOB74_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1219397.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(77910..78275)
                     /locus_tag="NOB74_000184"
     CDS             complement(77910..78275)
                     /locus_tag="NOB74_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCI1219398.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(78272..78637)
                     /locus_tag="NOB74_000185"
     CDS             complement(78272..78637)
                     /locus_tag="NOB74_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCI1219399.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(78829..79077)
                     /locus_tag="NOB74_000186"
     CDS             complement(78829..79077)
                     /locus_tag="NOB74_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219400.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            79076..79204
                     /locus_tag="NOB74_000187"
     CDS             79076..79204
                     /locus_tag="NOB74_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HCI1219401.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            79261..80955
                     /locus_tag="NOB74_000188"
     CDS             79261..80955
                     /locus_tag="NOB74_000188"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HCI1219402.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            80959..81078
                     /locus_tag="NOB74_000189"
                     /pseudo
     CDS             80959..81078
                     /locus_tag="NOB74_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            81055..81351
                     /locus_tag="NOB74_000190"
     CDS             81055..81351
                     /locus_tag="NOB74_000190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219403.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFLTWLDLLPQMQA
                     FEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLPRGYEKGV"
     gene            81729..82862
                     /locus_tag="NOB74_000191"
     CDS             81729..82862
                     /locus_tag="NOB74_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HCI1219404.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            82893..83213
                     /locus_tag="NOB74_000192"
     CDS             82893..83213
                     /locus_tag="NOB74_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HCI1219405.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(83242..83706)
                     /locus_tag="NOB74_000193"
     CDS             complement(83242..83706)
                     /locus_tag="NOB74_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1219406.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(83837..85090)
                     /locus_tag="NOB74_000194"
     CDS             complement(83837..85090)
                     /locus_tag="NOB74_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1219407.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(85119..85436)
                     /locus_tag="NOB74_000195"
     CDS             complement(85119..85436)
                     /locus_tag="NOB74_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI1219408.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(85462..85782)
                     /locus_tag="NOB74_000196"
     CDS             complement(85462..85782)
                     /locus_tag="NOB74_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1219409.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(86246..87661)
                     /locus_tag="NOB74_000197"
     CDS             complement(86246..87661)
                     /locus_tag="NOB74_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1219410.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(87678..88994)
                     /locus_tag="NOB74_000198"
     CDS             complement(87678..88994)
                     /locus_tag="NOB74_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1219411.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(89144..89842)
                     /locus_tag="NOB74_000199"
     CDS             complement(89144..89842)
                     /locus_tag="NOB74_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCI1219412.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT        26179 a        18965 c        15418 g        29430 t
ORIGIN      
        1 aaaaaactat tcacttggca ggacctccta ctaaatcagc gacaaaacgt cggctgaaag
       61 acttattttt ttatttttct tctaaacttt tttctacctc aatcccccaa gaatctttct
      121 tgaagtgatt gatgatcaat ggaataacga acatgaccac tgtgatagct gctactaata
      181 atgcatcact caatgtcgct gtacctaatg tagcaaatac gacaacgatg atagagaaga
      241 tcagcatgca gctgactacc caagctaatc cgtttccgtt tttaccaatt cggtaaggac
      301 gttcgaattc tggatgtttc ttacgcattt taagcaatga aacagcaatc aaaatgtaca
      361 cgatacaata aataacagtt gtagcatttg taagtgtcaa gaatacagca cttacgtcat
      421 ccattacacc ataaagcaaa gcaaataatg aaataacgat tgattgtgtt agaacgacat
      481 ttctagatac gccgtatttg ttttctttat ggaatccgaa ttttggtgga aggaatcctt
      541 cacgagctac ttggatgatt gtttttgatg gtccagtaac ccaagctgat aattgtaaaa
      601 gcacaccaat aaataccatg aagctgaaga tatttccgat cacttctggt aagcctagga
      661 tttgacagtc aatcaagata ggctgcgtga tatttgctaa ttccattttt ccatctggta
      721 cgacatttgc tacaagcatc gcattgatga cattcaataa aactaatccg atcaaagcga
      781 taaatacgcc ttttgtataa ttttttgttg cgtctttcaa acgaggcatg taaacagaac
      841 tcatttcgat cccaacaaaa ataaatgtga taccagctaa gtatttcaat gaatcaatat
      901 gttccaagtc agggaaagct tttgaccatg aaaagtcacc tagatagccg tttgagacta
      961 gtccgacttt gaaggctgcc aaaacaccta aaacgaacat gatgactact gggatatata
     1021 cccctagcca tacaccgatg ttcccgccga cttttgccat atcgaatttc aagttcaaga
     1081 tcgtgatgat ccagtagata actaaaatac aacctaaaac gaaccagtga ttattgccaa
     1141 gttctacatt accaaatgtg tttcctaaca atggtcctaa agtagaagcg accattacca
     1201 tacctgggaa catttgcacc cataatagcc atgcaacgac aaatccccat ttgctgccca
     1261 gtgctgtttt tacccataac tgaggaccgc cttcttgagg aagcatcgtg gaaagctcac
     1321 cggaaaccat tgatatcgga ccggcaaaaa acaaaactgc aaaaattgaa taaaaaatca
     1381 atgtccaacc gactgcggct aacgtaggaa tactccgaac cgttgcacac agtgccattg
     1441 tcagaccgat aaaggtccca agacccattt tacttacttc agatttactc accgttgaca
     1501 ctctccttga ttttttggat aaaataacgg tgtctttgaa gtagtttcag caataaacga
     1561 aacaattcag cgaatatttg aggggattct ttgagtttat tgcttgaagg gtttcttcaa
     1621 agacaacctc aaaacaaagg gatcgaagag cttaggtctc cccttgctct tcagatccaa
     1681 acatgcgtca gaaacagtta gtattcaagc tgttttctaa catgattacc ttgcttattt
     1741 tgcttcgctt gccaataatt ggtctgcgta gattttttcc aatttttctt gaagagctgc
     1801 tttgattttt tcagcatatt cttcaaagtg ttcttctttg ttcatgtatg gtgtcattac
     1861 gctggcacgc aatacagtta cttttccggc acggttccat tcttcatctg agaatcctag
     1921 ttggttcaca aattgtaatg ggctgttgcc atagtctggg atagcaaagt cagtatgtga
     1981 agttaagaac tcattaccgt aaatgcttcc tttcacgtat gaagaataat catatacgtc
     2041 atggttcaat ttattcattg caactaagtc atcgttgcct ttttctttga atacatagtc
     2101 taccatattg aaatctggat aagttaatgg atgaacttcg atttctttgt ctcctacttt
     2161 aaatgacaag tcattcaaga agttgtagaa acgatgtgca ccttcgattg atgcacccat
     2221 taatttacca tatcctgtga cattcaaagg taagacatgg tgtgctgccc aaacgctggc
     2281 tgctgttgcc cctgcttttg aaccttccaa gatataagcc ccaagtaatg ctgggatatc
     2341 tgcgcctttt tcaaatacat atgtcgcaaa gtaagagata acgtctctca tgcggatatc
     2401 tttgatgacg ataccaccgg cagaatatgg aacatagccc attttatgtg ggtcaatcgt
     2461 tacagattct gcttcttcga ttgctttata tgcactgtgt acttcttcta agatataatc
     2521 tttgttttct gtaaagacat tgtatttgta atgaacatct tttaaatctt caaatggaat
     2581 gaagttgttg tcttcgtcta agaaaatcgc acggccgtat ccgccataag cagcatctac
     2641 gtgtaagtag aagtaaatac cgtctttttc taatacgcga cgcaatgcaa cgattttatc
     2701 gataccgtcg attgctcctt cttctgttga tcctacaaca ccgactacac ctaggattgg
     2761 tgttttttca gctgctagac cacgaacgat tttttcaagt tcgttgatgt ccatgcgata
     2821 gttgtggtca actggcactg gaatcacttg gtctaaaccg ataccgatga tgtcggcagc
     2881 ttttagccat gaatagtgtt tagtttgtgg aaccaaccat tttcctaatt tttctaaatg
     2941 ttttccgcta cgtgctgagt gagctttgat ttcgtcgatt ttttctggga cgctgtctaa
     3001 cagattcatg atttcttctg ttgacaagtt cattaattcc caatcgcttt ttccagcaac
     3061 tagttcaggt gtcacttctt tcattgcaag cggcaatgat ttgatgttgc gggcatacca
     3121 aagtccttct aagtttgcta aagaaccatc agcaacgatg tggccccagc catctttata
     3181 gctcattaat tttgcaaatt ccattcctac ttcttcttcc atttggcttg ttgcaggaga
     3241 agattcatag gcaacgttat taccattcca tagcatagca aaattgtacg ctagtaaaga
     3301 tggcatcaat gtttcagagt tcatatgacc ccagtaacgt ccggcattat gccaaggaac
     3361 ggaatgggta cgcatccgcg ctgaaatttc tgatagaaca tcctttgttt tattcacagt
     3421 gtgttcaaaa ctagcactgc ttttttcttc tggcgtaata ataggcatgt cttgaggcat
     3481 gtagttttga cgccagccta aatgttcatc caccaattca ttcaacaaag ctttatagat
     3541 ttggccgttc tcagctttgt ccccaatgaa tagggcattt aggtttagat ctttcgacaa
     3601 tgattcactc atagtgaaac cctcctaaaa aaatatttaa attttgtcga gccctacatt
     3661 acacctgttc ttctattctg taaactaagt tttggcctga tttttaatca tattttaata
     3721 tgtatcaatt atccgaattg ttcacacttt tgaaataatt aaaaaaaacg agggaattta
     3781 caaatgtaaa ctccctcgca aagattgtat taacgacaac cagcgttcta ttttaggatg
     3841 ggtttcaaaa ttggaatgtt gtaatagtat ttcccttttt caaggtaaaa acttactaaa
     3901 ttctaatcaa ttactttggc caaaaagtaa tttttcttac cttttcgaat aaccacaaac
     3961 ttaccatcga attcatcgga tggatttatg acaaaattta aatcggtaac gcggtcaccg
     4021 ttaatactta tagctccgtt tgaaacatct tcacgtgctt gacgtttaga tggttcaatt
     4081 tttgtggaaa caagcagttc cacgatattt tcaggtgtgc ttgaaatttc aacgttcggc
     4141 attttaccga atccttgcgc gatttcttcc gcatttagtt ctttaatatt tccagagaac
     4201 aatgcttgcg ttattttttg cgcttctttc aagtcttctt cactatgcac aaatcttgta
     4261 acttcttctg ccaaacggcg ttgtgcttca cgtttctcag gttctgtctc tacttttttc
     4321 gctaagtctt cgatttcttc ttgagacaag aaagtaaaga atttcaagta tttcactaca
     4381 tcgcgatcat cttgattcaa ccagaattgg tagaactcaa atggtgaagt tttcttcgga
     4441 tcaagccaaa cggcaccgcc tgcagttttt ccgaatttcg ttccgtcagc cttcagcatc
     4501 aatgggatcg ttaaaccgaa cgcttctgct tctggtcctt ctaattttcg gattaggtct
     4561 aatccagctg tgatatttcc ccattggtct gctccaccga tttgcaattg cacatcgtat
     4621 gttttatgca gatgcaaaaa gtcgatagat tgcaggattt ggtaagtaaa ctctgtaaat
     4681 gagattccta cttccaaacg gctggcaacg atatcttttg ctaacatcgt gttgatgttg
     4741 aagtttttac cgtagtctct caaaaattca agtaaagaga tttttgacaa ccagtcgtag
     4801 ttgttcacaa atgtgatatt tgcatcttta ccaaacaatt ttctcatttg attggaaagt
     4861 gcgtccacgt tatgttgcac ttgttccatc gtttgcaaca cacgttctgt tttgcggccg
     4921 cttgggtcgc cgatcgttcc tgttccgccg ccaatcagaa tatatggatg atggcctgcc
     4981 aattggaatc ttttcatcat cataaatgga atcaaatgtc cgatatgcat cgaatcacca
     5041 gttggatcaa cgccgcaata aagtgaaatg ctcttttctt caacgagctc gcgaagtctt
     5101 tcttcgtttg tttgctgatt aatggcgtcg cgccaagtta attcatcaat aatattcatt
     5161 ttactgacct ccgtgtagtt tttttatgaa agcaggaacc tgctagcatg tgtaattaat
     5221 tatttcttca ggataggata ggaaataaaa aaagtccctt ggcatataag ccaagggacg
     5281 aaatctcgcg gtaccaccca atttgtatgt ctagatatcc aacatacctc tcgaacattt
     5341 aacgctgtcg cgtggcaatc actgccaaag actcctgaaa tgtaattcgc tttaaagcat
     5401 gtactggttt gcagcgacca ccagctttct gaaacattgg ctttaacaac tacttcgttt
     5461 cgatcttcgt cttgttatta ttaatatgtg tctatcatag agcgcaactt tttctttgtc
     5521 aacagaaaaa ggatattttt tttaaattcc tcattttttc ttttttgaat ccgctctaat
     5581 tccgaacatt ttattttcaa ttattgttaa aagaaataac tttttctgta ttttttctgc
     5641 aatttatcga gaagtcactt tactttgcct cttattcttt cttcgttaca ataaggaatg
     5701 ggacaagtaa aaaaatgaaa aagcaaggga cgaggtatat ggaaaaaaag caaaaaatta
     5761 ttttaggagc cacttctgct ttaactatcg ttattttaat tctaagtttg ttttttgtca
     5821 tccgatcatc tacaaaaaaa gaaccaatca ttcctgaaaa aaaaataaca gaaaaagcaa
     5881 aagaaccgac agatgataag caacaactag ttactcaagc aaaaaatctg gctcaaagct
     5941 acgattatga ccaagcgatt gcgttattgg aaaaagatag taagaacgga tctactgaaa
     6001 cacaacagct tcttcaaaca ctaaaaaagg agaaagaaca actgatcgac tggtctgatc
     6061 ctactcagat ctctcatgtc tttttccaca gcttgatcgt ggacccgcaa aaagccttcc
     6121 actctcaaca ggcacaagga tacaaagatt atatggtgac tgttgaagaa ttcaaccgtt
     6181 cgatcgaaca actttatcaa aatgattttg ttttagttaa tttgaatgat ttgatccaaa
     6241 aagacgaaca aggaaatctt tcctttaacg ggcttgcgct acctgaagga aaaaaaccat
     6301 tggttctttc acaagatgat gtcagctatt atgaatatat ggataattcc ggttttccta
     6361 gccgattggt cgtatcaaat aacaatgaaa tcaaaaatgt ctataaagag aaagataaag
     6421 aagaaatcgg tgactttgac atggttcctc tgatcgatgc ctttgtcaag aaacatcctg
     6481 atttttctta tcgaggcgca aaaggtacct tggccctgac aggttacaac ggagttttag
     6541 gttatcgaac atcaaaatct caatatggag acaatgaaaa aacaaaaaaa gagattaaag
     6601 aagctaaaaa agtggcggaa cagttgaaga aagacggctg gagctttgct tcccatacat
     6661 ggggtcactt gaatatgact caagcttcac tagaagatgt aaaaaaagac aatgaattgt
     6721 ggcagcaaga agttgcacct atcctaggaa aaacaaatat tctgatttat ccatttggtg
     6781 cagacatcag cgactggcag ccttattcag cagaaaatca aaaatttgct tacttgaaga
     6841 gtcaaggttt cgatattttc tgtaatgtcg atgcttctac accagcttgg ggacaattag
     6901 gtacggattt ctatcgaaat gctcggatca atatcgatgg cattcgtttt caatctgatt
     6961 tagacggaaa aaatcctatt cttgatccat tcatcaatgt ccatgatgtc tatgacaaag
     7021 aagcacgcga atctgcttga ttttacgtca tttatgaacc aaaaaagccg aactgacatt
     7081 ttatcgtcag tttcggcttt tttatgcttt atttcttctt cggtgcgatt cccttgatca
     7141 ggacttctgt ccattctgct gtatatggaa gcagttttgc gtatatctcc ggcttagaaa
     7201 ttccttctac cattgcttga aaatagagga tcaagaactc atccgaatat ttcaaatcca
     7261 cttttccttc tttccgccct cgatggaaaa gatcaagcat gatactgaaa ctttcttgcg
     7321 tatacgcatc catcgcgtca gaaaattctt ttttttcttt ttttgtatag tatgtcatca
     7381 aatcgatata aaattgtttg ttcactcgat tgagataacg gattttgttt tcactcatgg
     7441 caatcagtgt ttcttcaaat ggaagatttt ccgcaatcaa cgctttcgct tcttgcccta
     7501 aatcattcat aaatgcaaaa aatacttcat aaatcagccc ttccttgctg ccaaaatatt
     7561 taaaaatcgt cgctttactt acctgagcgt tctcagctac cttatccatt gtcactccag
     7621 cggttcctat gtctgtgttc atcaagtcaa aagctgcttg taaaatctct ttctttttct
     7681 cttgtgctct cttttcaaaa ccgttcattt gtagagcctc ccgtaatttt aaacttttat
     7741 aatatatata gttcaaattt attctgaggt ttattataac tatctattga gaaagtatca
     7801 agctagcaat tccttgttta tgaattcatt gacagaaatt tataaaaaga atattatgta
     7861 ctaaaataat aaaaaaaagt tttataaaaa ggtataaaac ctttttatta aactatttaa
     7921 tcttgtttag tatatatttt tagaaaaagg agtggggttt ttatggcaga aatcgtcaaa
     7981 gtcacacatt tgaaaaagag ctttggtcgt ttcgaagctt taaaagatgt ctctttcacc
     8041 gtacattcag gtgaagtcgt tggatttatc ggaccaaatg gttctggaaa atccacgacg
     8101 attcggacac ttttagggat tataaaaaaa gacggcggaa cggcaacgat ttttgggcaa
     8161 gatgtatggg aagatagttt atctatccat gaacgtcttt cttatgttcc aggcgatatc
     8221 tctttgtggg gaaatttgac tggaggagcg atcatcgatc tcttcatgaa gcttcatgga
     8281 aaagggagtg ctcaaaaaaa agatgaactg attcaacgtt tctctcttga tcctaagaaa
     8341 aaagcaaaaa actattcaaa aggaaatcgc caaaaagtgg gcttgattgc tgctttggct
     8401 gttgattcgg atctctattt atttgatgag cctacttctg gtttagatcc tttgatggaa
     8461 acgattttcc aagaagaagt tgaaaaattg aaagaacagg gcaaatccat cctactttct
     8521 tctcatattc tcagtgaagt cgagcgacta gcggataaag tcgtgatcat acgcgaagga
     8581 acactcgatg aagaaggaac actcgatgaa ttgcgtcatt tgactcgttc gaccatcact
     8641 atagaaacag aagcagagaa tagtcactta gcacaattga acggtgtcca tgactttgtg
     8701 caaaaaggtc acctcgctca atttgctgct gataacgaag ctttcgatgt gattttagct
     8761 gaagcgtcca aattaggtgt gaaaaaattt gaatctattc caccgactct tgaggattta
     8821 ttcatgagac attatgaagg atgaggagga agcgaaatga ctgataaatt ttcacgctgg
     8881 tccacccttt tttctcaaaa ccttagccgt gactggaaaa agatcctgat atggctagtc
     8941 ggtgtcactg ctttttctgg tggttttgtc cctgcgtttg aagaattgac ttccggacaa
     9001 ggattagctg gattatacga aaccttgcaa aacccggcaa tgattgcaat ggtcggacca
     9061 actccagctt cgaatgctgc tgagtatact ttaggagcga tgtatgcaaa tgaaatgttg
     9121 cttttttgca gtttgtttgc tgctgtgatc tctgttttac acgtggtgag ccaaacgaga
     9181 aaaaaagaag aacttggtct gattgaactt attcgttcct ttcgagtcgg acgtcaagca
     9241 aactctttag ctgtcatcgc tgaaagtatt ctgatcaatt tgcttttagc aatatcgatc
     9301 agctgtacga tgattttttt ccaagcggat tcgatcactg cagaaggtgc ttggcttttt
     9361 gggctatctg taggtagtat ggggattttg gggagtgccg ttgcactgtt tgctgcacaa
     9421 ctgatgccaa gttcagccag ttcgaatggt ctgtctttag cgtttttagg tggactttac
     9481 cttctacgag caataacaga tgtagctgat tcctcccttt cgatgtggaa tcctttaggc
     9541 tggtcttatt tgacctatcc atttacaact aacaactgga ttcctttgct ttatttgttt
     9601 ttgttcagtc taatcttgat aatcagttca tttgttttag aggaacatcg agatttgaac
     9661 accggctata tccccgaacg tgaaggaaaa ccgtatgcta aacgttctct tttatccttg
     9721 cgtggtttat tattctatct aaataaaggg atgacaatca gttggcttat cacttttggt
     9781 ttgatggggg cggcatacgg ctctatctac gggaatatgc aacagttttt agaaagtaac
     9841 gacttaatga aacagatgtt tatccaatct ggcgtctcaa ttgaaaaaaa ctttacaagc
     9901 acgatcatgg tagtcttgat ttgtctagct gctattttac caattgctag catcaatcgt
     9961 ttatttacag aagaaaccca cggacgtatg aatcagctgt tcgcaacaaa aatttctagg
    10021 aaccaacttt attggaccaa tatgttacta gctattctat ttgctatatt ggcaatcctg
    10081 attagttctg gtgcactagg gctttctgct ttggcttcga tgaaggatgc gaaagacatg
    10141 gatctattga tgtttcttaa agccgggttc aatttcctgc ctgccgtttt agtgtttatc
    10201 ggaattagtg gctttctatt cggatggctt cctcgaatcg gtaaacttgc ttatatctac
    10261 ttagcttact cctttgcact caattacttt ggcggaattt tggatttacc agaatggttt
    10321 tccaaaacag ctgtccctag ctgggttcca cggatgccaa acgattcttt tgatctttcc
    10381 gtgttcctta cgttatcatg tatcagcctt gcactgttcg tccttggttc tattggttat
    10441 aggcgaagag acttactaga aggataataa aaaagcatgt acaatttcat gctagcctcc
    10501 aaatctgggt caaaaatcca acatttggag gtcatttttt tatttacaag tcttctaact
    10561 gctctttatc aatgatccag acttctcgat tctttctttt tacataacca ttctcctcta
    10621 ataatttaaa ttttctagat aaagtttcgg gggtcgtacc gataaatgca gcaagttctt
    10681 tcattttcat tggcaggaaa aagtgatcct tccctgtcgc tttagctaag tcaagcagat
    10741 agacagcgac tcgttcttct actttttcca tcatcaaaaa agttgtctgc tgctgtactt
    10801 ttgttaattt ctcaacgttg attgctaaaa gtttcagact aagggcggga taatgcagta
    10861 agagttccga gaaatctttt tgtctcaata tgcaaatttc cgttttttct agtgcttcgc
    10921 caaataaaga ctcatttgga acgcctagca actggctctc tccctcatat ccgcccggct
    10981 ctattactcg taaaagctgt tcctttccgc tagcagataa ttgatacact ttcatactgc
    11041 cggaggccac gatcactaat tgaggttctc cattcggcgc aagaatctgt tctccttttt
    11101 ccacatagtg atgtttgaca agtgcgtgta ctttttcttg atcttgctgt actaagtgat
    11161 tgaacaaagg aacaaatgaa acacataaat gatcatgact cataatctct cctccttcta
    11221 aacagctatt tctaataaag aaacataact tcccttattc caactgataa ttttctttta
    11281 tcatagcata aacgtcaagc gaaccagata ccagcaaata gagtggattt ctttttgtcc
    11341 cttgctttat tttccttctt ttgagacctt aagtaattga ttcctatcaa ttttttaaat
    11401 atttactttt tgaataatca aaaacaaacc ttcactcgca agccgagagt aaggtttgtt
    11461 tttcgcattg cttatttcgt gttgtctatt gaaatttttc cgcacctagc ttttgatata
    11521 gtggtgctag ttcttgtaag gtttcagcgg ttatttgctc aacgtgttcg atttcttgcg
    11581 gatagaagaa tagtttaccc atttgaaagg ttcggtctct catcgctttt ttcaactctt
    11641 cttgtttctt tgtatcggac aaatagtcag acaaagctaa gtggtcgtca agttcatgtt
    11701 ctggttgcgg ccatatgtaa taatccttga tatcgactgt tttgctccac tctttcagta
    11761 tcgcaagcaa ctggttatac gctgcaatgc taccatatcg ttcttcgctt ttataatgtt
    11821 ggtacatcaa atagatttgg tattgttttt gattcaacaa aactgctaga caggcattct
    11881 cgtcttgacg agattcgctt cggtacgcgc tccaaaaatg actgcgtaaa ttccagccat
    11941 tcgtccagct ttcgatttta ggtttgctca tgccgtacat atcaggcaaa agtgcagctg
    12001 tctggagctg aatctctttc catttttgcc agtgttcttt atattctttc ttgatttgtt
    12061 caatcttatc tgttggatgg ctctctttga gctgtttgaa tgcgtagatt ggtcgatcaa
    12121 acaactgata atctgatttt ccaagttcca ttgtttcgcc tctttccgtt atcttttgta
    12181 ttctacctga attttgcgat atggacaaat agaggttgtg aaaaagctgt tctgcatcaa
    12241 gtcataagaa cagccaaaca aaaaactgcg atgagcatca ccgcagtttt attgaactta
    12301 aggttgattg atcacatcta aaagcgttga aaataaaatg gcactagaag cagctcctgg
    12361 gtcgatatgt ccgattgcac gctctcctag ataggaagct cgtccttttt tagctaccaa
    12421 gactttggtg tgttcttttg cctggtcaat gatttctttt gttaaattcc ctgccttcaa
    12481 tgcctctgtg actggcagcc aaacatctaa catcgtttta tcgtcagctt ctgcctttcc
    12541 tcggctttga atacccgctg ttccctgctc gatcacttcg cctaattttt cttgagaatc
    12601 aatagaatcg acctcttttg tcgctttcat catgttcatg aatgcagatc cgtataacgg
    12661 accagaagcc ccaccgactt tcgatatcat cgccatagag aatactttga atgtatcgct
    12721 gattgtttca ggatgatcgg cttgaaaagc ttcttcataa gctgaaaccc ctcttcccat
    12781 gttatttcca tggtctccat cgccaatcgg ggtatctaga tcactgagat attgtttgtt
    12841 ctgattgatt gcctctgcaa attgcgtgag ccattcttgg atttcttgaa cggttagttt
    12901 catattatca cccttttatc ttgagatttt ttaccatgaa atcgtctgta cattgctttc
    12961 taaagaatct ttccattgtg tctccgtcaa gtcgatcagt gttagagaaa gaccttgcat
    13021 atctagtgag gtcataaaat taccgacttt tcggaaaact acattgacgc ctctttcttc
    13081 caacagagct aaaacatcat tcatgaacac gaactgttcc atcaaaggcg tcccgcccat
    13141 tccgttgact agtacacctg cttcttttgg taaattcgag taatcatcta aaatcttagt
    13201 aacaagttcc tttgccagta ctttagaagg ctgcatcttt tctcgacgat agcctggctc
    13261 accgtggata ccaacaccat actcgatctc atcttctcct agttcgaatc ctggtttccc
    13321 tacttctggt acagttgctg ctcgaagcgc tagaccgatc gtcttagttg cctgtacgac
    13381 cttttctccc agttctttca actcagctag ggaagcaccg tttcttgctg catcgcccac
    13441 gattttgtgt acaaggacag tacctgcaac tccgcgtttt ccagcagtat acgtactatt
    13501 ttcaacggcg atatcatcat ctacgatcac actttctact tcaatatcgt ccatagcagc
    13561 taattccttt gccatatcga agttcaatgc atcccctgta taattcttaa cgatcagcaa
    13621 aactcctttt ccactatcgg cttccttaat agccgtctga atctgatctg gagttggaga
    13681 agtaaacaca tcaccaagca ccgctgcact taacatccct tcccctacaa acccggcatg
    13741 ggatggttca tgtccgcttc ctccaccaga aaccaaacca acttgttccg ctttctgatt
    13801 cttggctaca acacgggaag attctacacg atgaacaagt tctggatagc tttttactaa
    13861 tccttccagc atttcttcga caatattgct tggatcattc atgatttttt tcaatttatt
    13921 cccatccttt ctttccggca ttttgtgctt ctgttaagat ttgctgagta tcatctgtta
    13981 taccggcagt gatggctgct gcaaaagctc cttccactaa aggcgcatcc accagatgat
    14041 aacgttgctg ctgctcttct tccaacatgt cttttgccag ttccgagttc aataccgcgc
    14101 taccgatatc cgcaaaaaca aaataactag ctgcatcgct tgattcattg actgcttcta
    14161 cgattttcat cgggtctgat ccgatctcgc catttattcc gccgagagaa aaaatttgca
    14221 cctcttcgga tttttgcatc tgctcaatca tttctttaat accatctgtt actttttgac
    14281 tatgagaaat aagcaaaata ctttttttca caagaatctt cctttctttt acatagttgc
    14341 taacgattgg tttcgctttc attaatgaac aattcaagta tataataaat ttctaatttt
    14401 gggaaaatat gtgtagtgct tcttgaagtt tgttatactt taattaaaag agaggagtga
    14461 tcgaatgatt acaacaacaa cgaacagtgt agagggaaaa gccgtagtag cttataaagg
    14521 gatcgttttt ggtgaggtca ttactgggat ccatgcattt aaagacttgg aggcggggtt
    14581 gcgaaatatc tttggcggcc gctcaaaaag ctatgaaaac gaactaatgg gtgcaagaga
    14641 agaagcactt gccgaaatgg ccgaacgtgc aaaagcatta ggagctgatg cgatcattgg
    14701 cgtaaaaatg gactatgaag tattaggcag cgacaatggc atgctgatgg tcacatgtag
    14761 tggaacagct gtctccacga gataagtagg ggacatctgt tttaataact aaagagagat
    14821 gggacatgta gtggcactca agaattagat ttttcagtct aacttcgagg tactctacct
    14881 tcccatcctc tcttttttat ttctttttgc ggatgattcc gtaagctgct gcgactaaca
    14941 cacccgcccc tgctaaggaa taactgacag aagctgtttt ttcatttgtt tttggcaaag
    15001 tctgacttgt tgatttggat ggctctgtcg tttgctgaac tgtttctgtc gtgcttccag
    15061 aggtcactga tttttctcct gccgaatgca aaatatcttt tattcgttgg aaactagctg
    15121 ctaagtcagc tttttttgct tcaaaatcat tagcaactgt ttgtgcttcg ctgatctttc
    15181 cgtggattgc ttgactggcc gctgtgatat ccgcttgagt ttgacttagc tttccagaag
    15241 ctgtttgagc aacctgattt aattgctgat tgaattcttt tgcttgttgg atcttcccgt
    15301 caagatctgt ttggacagct tccgcttttg ctttcgcttc ggcaagcttt ttctcaagtt
    15361 gtgcacggtc atttcccact ttatttttaa gatcagctaa atcttgatcg attgctgctt
    15421 ggtcttcttt caatttgttt tttgcagctt ctaatgcttc ttcgagttct tttcttttat
    15481 tttccaagtc ttgcaaatga tcgatttggt cagaagaggt agaactattt attgatgtat
    15541 cttctgaaga tgaaatcgtt tctcctgaat tatctgtcgg tacattggaa gtcatttctg
    15601 tttccgaggc accgttttca gcaccagaag agcttatggt tgttgaaggt tctgtttgag
    15661 caggttcaga agtttccgca aaagctgtct gtcccaataa gaaaatactg gaaacagcaa
    15721 ttggccagat taacggcttc attctttttt tcatcacttt tcccatcctt actacttttt
    15781 aactaatttc ttattataag caaaaatgtt tggaagaacc ataaacacaa caggctgttt
    15841 gtctaaaaaa cggtgcatct tttatttttt tgtacgttcc gggcttttcc atgtcccgct
    15901 tccataacct aaaatcgttt tgactgctgg aatgaaagtc gtcacgatcg ttatcgcgtt
    15961 cactatccag aacaaaagca tatatagtgg tgcgaaaaga aggtatttca attttcttcg
    16021 tcgatcatct acaatcagcg aagctagcaa ctggaaaaat cctgcgacca tttcaaagca
    16081 gatgaacaca aaactgaatg taaaagtaat ataaatctgt tcgtagtttc cttgatatac
    16141 ataatgcccg attaatccag caaaaagaac tacggaaata caaaagaata ttgaccagac
    16201 aatactcaat gtttgatcaa tgaagatgat cgttcttcca atatgtttaa aaggatggag
    16261 catcactttt ttgaaattcg tcagccagac ttctgttcca ccttttgccc aacgttttct
    16321 gtgtcgatat agcatcttca acgtcacagg tacttccatg aaaaagataa tctcaggagc
    16381 aaaaacagat aaccagtcat ttaactgatg atcccaagca atactgatgt cttctgtcgc
    16441 tcgatcttgt ctgaatccgc ccacatcgat caaggcttct tttcgataca tcgtatttgc
    16501 tccactgtac gcataaagac caccgaaaac agctgactgt gttcgtttaa tgatgcccac
    16561 gatacttgag aattcaaccg tttgagattt tgcaatcaat ttggtacgat tttggacatc
    16621 catatttgca gtgaccgcag caatatgtct tgcaccaggg cgaatgaaat aattcacata
    16681 cctaatcagt gcatctggct ccggtaccgt gtctgcatca ttgcttaaaa tcaatttccc
    16741 ttttgcaaag gcaagtccga tattaaacgc gtgggctttt cctttatttt tttcgatccg
    16801 aaccacacga agattagcgt attttttcat cagtctagct aatatttctg gtgtttggtc
    16861 cgttgaacca tcgtctgtca ctaatacctc atagttgtga taattcaatt tcgtcatcaa
    16921 atactcgatt gtatattcga tcacaatttc ttcattatgg gctggcacca tgatcgtgat
    16981 gaacggttcg acactcaagg gaacatctac ccattctttt tgcttatgtt tgtataaaaa
    17041 cacataacac cagacaccaa taaaccatac aaatccgcct aaaatcggat aagaaacgag
    17101 aaaaaaatac ataatagaca aacaagtatc taagaataaa ttacctgtat gggtgattga
    17161 gatcatttca gttccacccc attttcttta tacaaatctg caatgaatgt cgtatctaga
    17221 tttttctctt cggagacaga ataaaaacgg accgtttctc tctcttcttt tgttccaaaa
    17281 cgttccgtat acacttcttc aagtaattct tgtctttttt tcaatttttc atcttcatat
    17341 tcaaaagatt tatttacttt tttgtataga tttcgattgt tccacctagt caatacaaat
    17401 gaggtaatca ggaaactgaa aaaaatcaat acaaaaaagc cgattaagaa atacagcatt
    17461 ttcttttctg ataaaaaagc gtacaaggaa aaatccttgg ctctttctgg tctcgttaat
    17521 gggaaaaaga cccatataaa aggaagaaca acgatcatcc atcctaaaag agccactaac
    17581 gtttgccaaa tctttaacca gtaattacct tttgaaaaat acttatcttt caccaaaatt
    17641 gatgcaactt cttctcttgt tacttttttc atatcctcac ctcacgtttt tttgttacga
    17701 cgtaggagtt taccatacat ttcatttctt ttcacataaa gtgttcctaa atttttccta
    17761 agaaaaagaa caaaacattt ctcatcagca aatgaaaaat attttgttct ttttatcagt
    17821 tgttcttttt attttttatc tcttaattat gttgctcttt ccaatacgac aatgcttttc
    17881 attcctctag atatcgccgt gtacatttgt ctgcgtcttc tttgctcatc tccatcgttt
    17941 tcaaatggat ataagattac atgatcaaat tccagtcctt ttgctagact caaaggaatg
    18001 atttggcagt tttctaatcc atatgaattt tttttaatcg attcttgtag cgtttgggtt
    18061 tcctcttctg tttgggtgat aactgccgct ttttctcctt ttagagaaac caaaatctca
    18121 gctagtattt tcaacaattc ttcagaggat cgaaaagagc ggtattcggg ttcttttcct
    18181 tgcggtcgga tcgatacgat gtcgatcttc tcttgatcca cagcataggt tttgaaaagc
    18241 tctgtgattg ctccgctaga acggtaacta tttctaagat cataccgatg gatcggcaga
    18301 tggtagtcgt cgaaacaacg cataatatca gcaaaagtag tggaagaatt aaagattgcc
    18361 tgattctcgt cacctactaa agtaaagtga gtttttggaa ataattcgat caatagacct
    18421 aattgtgcca gggtataatc ttgtacttca tcaatcaata gatagcgaaa tgctggtaca
    18481 tttacctttt caacaagtaa atgacgaata gctaatataa tgactgcttc atcaacagta
    18541 cgtgtgggtt gccaagcata agctgagcca tatcgttttt cataaattct ttcaaacaac
    18601 tgatgctcat ccacccatgc catttcttcg atttgtctgg ttatttttcg atattttttt
    18661 tgtaaaagtt tccttgcata agctacaata ctttgttccg aatcatcaga aatcaattta
    18721 ccgaataatt ccaactgcct atcttctgtc aacgagagta cctgattctg cacagcagga
    18781 ctttttgctt gtttcaaaag atgattcttc cattcgctca tcagtgcctt tttcgttgct
    18841 tgaagcctat cgatcaattt aggatgagca ggaactttct catatatttt ttcgatcgtt
    18901 tttttagaaa ggactgtttt tccattttta gtaagtccac ggataaaatt cggatgatct
    18961 aaaaacaaag gatctgattg ttttagatta tcgataaact ttttgctacg caaacgttct
    19021 gtctgctccg atacattttc tcccgtgata cgtttgaaat aagcctcttc accttctatt
    19081 tcctctgctg aaagctgtga aaccagctgt atgatggtta gattcagtgg atttctttca
    19141 cctaatgatg gtaggacatt cgaaatatag tcgataaacc gatgattagg tgatagaatc
    19201 agcaagtcat cggatgtcat cgtatctcga tataaataga gcagatacgc aatacgctgc
    19261 atgatagcag aggttttacc acttcctgct acgccattta ccaagatatt ttgacttttc
    19321 acatcccgaa tgattgtgtt ttgttccgat tggatcgtag cagtgatagc cttcatttca
    19381 ttggtctcat cttggcctaa gacttctaat aatacgtcat cttgaatagc tacagacgta
    19441 tcaaaaaact tgaccaaacg atctctttcc aaaagaaatt gtcgtctttc tttaataacc
    19501 gtatcgattt tattttgacg aaccgtataa gaagatggac caatcatgtt attgtaaaaa
    19561 agttcggcaa ttggtgaacg ccaatcataa acaagatttt catctgcatc atctgtgaaa
    19621 tttgctgtac cgatataaaa ggattctttt ggctcattat ccagaaagtc tacaacgact
    19681 tttccaaagt agggactttt caataaacgt tcgatctttg ctagctgatt ttctgcgttt
    19741 ttctgtttga tattcatctg atcgatttct ctatttttca tttcaatcat cgaaaaagta
    19801 tccaggttat ctaagtaact gtcaaaattc aatcgaagct cgccagccat ttctttcaac
    19861 gactggtttc cttctatttt tgccgtatcc atcgattccc gcagttcgtt tttttatcaa
    19921 ttagcttttg atacacgttc ttcagatatg cttcttctaa ctgtttttgt gtgttgacca
    19981 tacacattct cctctttttt taaagtggtg gaaccgatta gtttacctct tttaagagtc
    20041 gaatgcaagc tttttaacga gtatcatttg ttaggatata tcagttcttc aggtcggaca
    20101 gtttgatata aagaaaatgc accatcaagg ttttttacgt ggtagccaga ctgcttcaag
    20161 attctttccg ctagatagct acgtaatccg ctatgacagc tgacgatata ttcttgttgg
    20221 ctgtctaatt catttaatcg gtcccgaagt tcattcaaag ggatatgttt ggcttccttg
    20281 aatttgccct tttccaattc ttctgctgtt cgcacatcta ataaaatttt tccttttgct
    20341 agttctgtcg gcaattcatg ccattgtacg gtttcactaa gcccttctgc aatgttcatt
    20401 gctgcatatc ctagcatgtt tactggatct ttggctgagc caaatggcgg tgcatacgtc
    20461 aattctaatt ccggtaaatc gaagatcgtc aaatgccctt tgattgctgt tgctaaaata
    20521 tcgatccgtt tatccacacc ttttgcccca acaccttgtg caccataaat ctcgccagtc
    20581 tctggatgga agatcaactt cagtaaaata tctgttgctt ctggataata gcttgcatga
    20641 tcttttcctg atacatgaat gacttcaaaa gacagttcgt tttctttggc tgttctttca
    20701 cttaaaccgg tggatgcggc agtcattcca aacgttcgta taattgctgt tccaataccg
    20761 ccttgatttc ttcgagaaat tccggaaatc gtgtccgcaa cttgtctacc ttgacgattg
    20821 gctggtgaag caagagaaat aagtgcatct tttccagtga tttgctgttt tacaacgata
    20881 gcatccccca ccgcataaat atcaggaata ttcgtttgat aacgttcgtc tactaggata
    20941 cccccgcgta tgcctaattc gattccagcg gtcactgcta gctggttatc aggacgaaca
    21001 ccaatggata aaataactaa atcagcaggg atggtacgcc catcatccag tcgcaatcgt
    21061 ttcccgtggt cttcaaatcc agcgacagca tgagaagtaa tcacttctac tccttgatga
    21121 gacaattctt tttctataaa agctgccatt tcttcatcca gtgttggaag aatatgtggt
    21181 gcttgttcga tcaccatgac ttctaaacct cttcttttta ggttttctgc catttccaat
    21241 ccgatgaatc ctgcaccaac gatcacggca cgctttggct gtttttctaa tgcatgcatc
    21301 actttatcga tatctggtac atttctaata gaaaaaacat tgtcggcttc tgttatccct
    21361 ggaatcgatg gaacaactgg ttttgcacca ggagataaaa ccaatgcatc gtactgttca
    21421 atgtgttttt gaccctcatg tacgacttct accgttttgt tttcgggaaa gatggctgtc
    21481 acttcatgat ttggacgcac atctaaacaa aaacgagcgg ataatgattc tggcgtttgg
    21541 acaagaagat tttcccgttc actgatttct cccgaaagat aataaggcaa gccgcaattt
    21601 gcaaaagaaa catacggtcc tttttcaaaa acaacgattt ctgcatcttc cattaatcgg
    21661 cgaagccgtg tagcagcaga cattccacct gctacacctc cgacaataac gattttcatc
    21721 ttatttccct cctactgttc gatcaaacca ttgattcatg ccaccacgta cattcactac
    21781 atcataacca gatttcttta attctttagc tgcttgttta ctcctcatcc ctgattgaca
    21841 aatcacatag acggtctttt ctttgtctcc atcatatctg tttatacttt gtaatggaac
    21901 atttttagct ccttttatat gcccgccccg gtattctgca ggtgttctaa catcaagtaa
    21961 cgctggattt tccaaaagct tttcctttaa ttctgggact gttatcgatt ttattgattg
    22021 aaatagcaaa ttcattttct gcacctcatt tacattttta taaatacctc atggggtata
    22081 ttaaacagga gctttattaa tatgtcaacc agaatgactc ttcatttttt tcactacttt
    22141 ttatatttgc ataaaatacc gataaggggt attatctaat tataaaaata gaggagaatg
    22201 tgttatggag attgataata aaaatatcct gaaccgtttg aaacgtacag agggacaaat
    22261 tcgtggtatc caaaaaatga tcgaagacga aaaagaatgt atggatgtca tcactcaatt
    22321 aagcgctgtt cgttctagta ttgatcgcgt aatgggcatg atcgttgcag ataatctgaa
    22381 aaattgcttt gagaaacctg atagtaatcc agaagaacaa gcggctaaac tagaacaagc
    22441 gatcaagatg attattaaaa agtaaaggaa tgatttcaat gaaagtcgtt ttccatattg
    22501 atgaattaga aaaatggtca gaaacaggga aaaacgtaaa aaacctgata aaagcttctc
    22561 cagaaacgac gattgtcgta tctgtaaatg gcatcgcgat taccggttat ctagactctg
    22621 ccaatgcaga attcttagat ttgcaaggag tcgtttttca cgcttgcgcc aatgctatgc
    22681 gtgctaatca tatttcagaa agttctttac ctgaacaagt aatcgttgta ccagcaggtg
    22741 tccttgattt agttgaactg caatcccaag gttatgctta tatcaagcct tagtcagtag
    22801 aggttgcgac agaagtgatc agcttcaaga aatttcggct tatttttcga agaagctact
    22861 tctggaaaac cgtgaatcaa aggttgtgaa aacgctgtcc tgcatcaagt aataagaaca
    22921 gccaaacaaa aatagcttct catatttttc gtttggttgg gcttattacc gcagatgcaa
    22981 gcttttgaac accgtttaag gaagaggttg tgaaatcagc ggtttgacct aagtattaga
    23041 gaaaaaaacg ggaaaatagc tcctcatatt ttgccgtttt ttgagctaat accgaaggtc
    23101 agctgattga acaccgttta aggaagagat tgtgaaaaag tcgcttagtt tcgagtatta
    23161 agaaaaattt tgtgaaaatg gatttctaca tttttgcata aatttggctt aataccgaga
    23221 aactggcttt tgaataccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta
    23281 ttagagaaac aaacggaaaa atagctgctc atattttgcc gttttttgag ctaataccga
    23341 aggtcagctg attgaacacc gtttaccaag aggttgtgag cctaccattt aactccgaat
    23401 cacaagaaat aatttcaaaa acaacttctc ctgtttttgg ttcggttggc ttattatcga
    23461 gaagtagcta ctgggagtct atttatcaaa aaaaggaatg cgacataggt cacacccctt
    23521 ttttattttc tttgaaacat ctttcggtac tcgacagcat acaagacaaa agattgtaaa
    23581 agaccgtaag tgatgacggc aaaaatgact ctcacccaca gcgttggtaa ttctgggaaa
    23641 agcagcaaaa ggatcatgcc aacatagatg acagcagtcg ctactttgcc ataccacttc
    23701 gctccactta atttgatatt tttagatagc ccgattaatc cagctacaaa cataaagcct
    23761 tcttttatca agaatagacc aaacaacagc caaagccacg gtcgatacca tgccatagac
    23821 aaaatcagaa aaagttgtgt caatttatct gcaaacggat caagcacctt ccctaagtct
    23881 gttacctgat tatatctccg agcaatgacc ccgtctagat aatcagacaa acctgagaca
    23941 acaatgaccg ctcctgctat ataaaatgac tgtctcagca caaaataaag ataaatcggc
    24001 agcaaaaaaa tacggaatat cgataaaaga ttcggaatcg tttgtatttc tttacgccag
    24061 tctgtgctta atttcatttt atcgccctac ctcctcagca ctcttttctt tttattttag
    24121 cttacacggg gaataaaacc aatgatttca ctgtttttat ttttctttac agacactgat
    24181 attatgagct aatttgagat aatcacttgc tgttttcatc gtttactctt ctttcttcct
    24241 gtcgtttgcg catttctttt actagtactt tatgagcttt ttttgatcct cgctctaggt
    24301 cacgctgccg tttacgtgtt ttataatcga taaacagact gtctaaatcg taacctgtcg
    24361 ggtacagatc ttctgctgaa cgcaccagac gaacacgctg acgaggcacg tggattattt
    24421 ttttgtctaa atatacatca atcgtatctt cacctatatc ttcataaact aacgcttctt
    24481 tttggtattc attgacaaat atccgatcac cttttgcaaa gagctgacgt tcttttttat
    24541 tctccttcct atttgtaact gctgtcttag gaagaaattc ttttttctgt gtccgatagg
    24601 ctttttccgc caagtaacgc tctgcttgat ggatcaattt catcgacata tccattttat
    24661 gagcaatcca caaagcttgg ctttctcctg tttcttccaa cccgcaactg atatttagga
    24721 cgaagtgctt cccgatcgaa agccatagca gccggcacaa aatcttcatg atctccggcg
    24781 aatttcttga tttctccata atgggtcgtg gcaatgatca atgccccttg ctcatacata
    24841 gattccatga ttgcgatcgc tagtgcagcc ccttcatttg gctctgttcc actgccaatc
    24901 tcatctaaaa gtaccaacgt attccttttt atctttttca aaatagcagc gatgttttgc
    24961 atatgaccag aaaatgtact caacgcattt tctaaatttt ggtggtcacc gacatcgacg
    25021 aaaatctcat caaagacagc aagctctgtc ccttcttttg ccggaacttg cataccgaac
    25081 atcgccatca aagtcaataa accgactgtc ttcaacacga ctgttttgcc tccggcattt
    25141 gctccggtga taatcaagcc tcgatagtct ttaccgattt caacatccaa tggtaccgca
    25201 tgctcaggta aaaatggatg tctgccttgc ttgataatga tatgttccga tttattgatt
    25261 ctaggtgtgc ttccattgat ttctcggcta aattttgccc gagcaaagat gatatctaac
    25321 accgtgatcg tttcgatcaa taaatcgatc acttcttcgt tttctgcgat agcaccagtc
    25381 aatgccgcca ggacttgata ttcttcactg atttcttcag cttttaacaa ctgatagtgt
    25441 tcattcaatt tagaaatcac agttggttca ataaaaaccg tcgttctttt atttgattca
    25501 tcgataatcg ttccatctat tttattttta tagctggctt tgataggaat cgtatagtat
    25561 tcgccttttt gaacaatcat tgcttcttgg atcatttctt tgtttttcgg atgacgcaag
    25621 aatttcagta attttgactg gatttctttt tcgattagtt gtaattgttt gcgtacttta
    25681 cgcaaattac gtgacgcgtc gtcactgact ttattatttt ttattttctg gtcaatcaac
    25741 tcttctacat ttatcaaatc aggaagatgt ttgctataag caaacaacaa gggtgtctgg
    25801 tattgattct tatcaaaaaa ctttgtgatc atccgactgc ttctaagaaa atccgcatat
    25861 tcgatcaaat cggttggctg cagaatcaac ccttttttga cttgttctgt cagtgcatcg
    25921 atcctcggca accccataaa tggaacatgc tgactgcttt ctaagatcaa gcgtgcttct
    25981 cttgtttctt cttgacgatc caagacagtt tgtaggtttg tcgagaccgt catatcgctg
    26041 attcgttttt tgctatagtt tccaattgct cttgcttgga tttccttttt gatccgatca
    26101 aattgtaatt gactaatcat ttcgttgtcc atattctctc cttttcttga agagatacct
    26161 gtcccaaaat aaataagggc ctagagataa ataaaaggat agaacacagc ttaaaaaagt
    26221 catgtcctat ccttattaga atacaaagat attgttttcc tgacaggtac cgtttcataa
    26281 gcacaccaaa taaactttgt ttattggcta ttcgacttac tgattagata ccagctacac
    26341 tcacaaaaca taccccattc ttctaggtct tatttatttt ccacttaact atagcaagac
    26401 acattttggt tgtcaaactt tagtatgttt tatagattta caccattaat gaatagacac
    26461 ctaccgcgat aattgctccg atcattggac ctgcgattgg tacccatgaa tatgcccaat
    26521 ctgaagttcc tttattagct attggcaata ccgcatgtgc taatcgagga ccaaagtccc
    26581 gagcagggtt gattgcatat cctgttggcc ctcctaatga aagaccgatg gctaagatca
    26641 atccacctac agcgaatacg ttcgttccag gtgcaaattc gttttgtcca aaagctagca
    26701 acccaagaac taatacaaat gtaccaatta attctgtgat cacatttgct ggataattcc
    26761 gtatagcagg acctgttgca aacgttccta aaatcgcgct ttcatctttc gttgcattcc
    26821 aatgtggcaa ataagaaagc caaacaagaa tggcccctgc aaaagctcct aaaacttgcg
    26881 caatgatgaa aggaacgaca agattccaac taattgcccc tgtcatcgcc atagctagag
    26941 agactgcagg attcaaatga gctgggccca tgaatccaga aatatagaca gccattgtta
    27001 cagcgagtcc ccaaccaaat gcgatgacaa tccagccaga agcctgtgct ttacttttgt
    27061 ttaaattcac agccgcacac acaccatctc caagcaaaac taggatcagt gtcccaataa
    27121 actcccccat gatttgagtc atatcactgt tcatttattt ctcccccttt agttcccgca
    27181 gatctgattc tgcaatcaat gcttctaaac gtttagtctg ttgcgccttc tcctcttctg
    27241 tccattcaaa atatccagca attgcatcga tcacaggttg cttgatctca tcaagctgat
    27301 ctcgttcaaa caacagatga tttgtacgac gaatgagata atcgcctggg gccaaaacca
    27361 tttcttcttc taaaccataa cgtaaccgag ctgactcagc gagactcaaa ccaggataag
    27421 gtgccatttc ttttgctaat tcaaagatac gtcgggcatt agtcccgtaa aaatcagcga
    27481 tataagtagc atcttcttcc tctaaaccgg ctgctactcc ttcttttgct aattctgtca
    27541 ctgtttcttc taatttagtt ggatcgaagt ttccacctga aatctgatat tttttagagt
    27601 cgatttcttt cgtctctatt ccgtattctt cttttaataa ttggcgtatc aatcgcaaag
    27661 ctccttctgc catcttacgg taatcggtga ttttcccacc agataaagtc agcaaaccat
    27721 ctggttctct ttctaaagaa ctacctctgg aaatcgtaga aggtgctttt tcatcacggc
    27781 tgttttccaa atggttcaac acgtcttcta cttcagcacg agaaactttg ttttccttat
    27841 attcacttac tgtatcgaca actttattga agctcttgtc tgaaatcgat ccattatctc
    27901 caccattgta atcagaacca gaattaccaa tcaacagtgg acgaagtcct gcccagcttg
    27961 cttcgatatc attcaatgtg atatttgctt ctggatagcg atgattgatc acatccaata
    28021 gataatctac atcttcttgt gtgactttcg gatccgtaaa atctccttgg taatccgtat
    28081 ctgtcgtacc aaagtaagtc ttgttttctc ttggaatagc aaaaaccatc cgcccatctt
    28141 gctttcctgt atcgaagtat gtgggttgcg gtacaggcag ttttttcgca tctacaacta
    28201 aatggatccc tttagttgga cgcattttag gagagactgg acgcgtaaaa ttcaagtttc
    28261 gtactttatc tacccaagga ccactcgtat tgatcactaa ttttgctttg atttcgatca
    28321 cttcatctgt cagcaggtca cgagctttga cgccaacgat ttgatcgcca tcatataaaa
    28381 agccaaccgc tttcatttta cttactagat aagccccatc ttcggcagcc tttttgatat
    28441 tatcaatcac taaacgggca tcattgttgc ggaaatctag atagacaccc gcgcctttta
    28501 gcccttcttt tttcaaaaac ggttctcttt ccaatacttc ttctggtgtc agcgtataat
    28561 tctcatattt ggttcctgtc acatttgcca gtttgtcata aaggtccatt gctactttga
    28621 ccgagaacat attgaaggtt gttgctcctt cgccctcata gattggcaaa agcattggat
    28681 ctggttttgg gatgtgtggg gcaatacttt gtacgactgc acgttcacca actgtgtcag
    28741 ctactacttc cacatcaaat gtcttcagat aacgaatacc gccatgaaca agtttggtcg
    28801 agcgagagga agtcccttct gcaaaatcct gcatttcgat caatcctgtt ttgattcctg
    28861 atgctgctga ctggactgcc acaccggcac cagtgattcc gccaccgatg atcaacagat
    28921 ccaattcttc ttgctgcatt ttttgaatgc tatcttgtct tgtcttgttt gaaaacatat
    28981 ggatttcctc cttattcaaa tgcttgggta gcttttactg cttttttcca accgttgtaa
    29041 agtttttctc ggcgctcttc ctccatttga acttcaaata gcttgccagc ttcataaaat
    29101 tcgcggatct cgtctgtatc tttccaataa ccgacagcta atcctgctaa aaatgctgcc
    29161 cctagcgccg ttgtttccaa gttttctgct cgttggatcg gtacattcaa gatatctgtt
    29221 tggaattgca tcagatattc attgtttgct gcaccgccat ctactttcaa tacaggaatc
    29281 ttgattccag tgtcatcttg catcgtatcg atgatatctc tcacttgata agcaatcgac
    29341 tgtaaagtag ctttaatgat atcttctttt gtcgtaccac gtgtcaagcc aaacatagcc
    29401 cctcgtgctg cctgatccca ataaggagca cctagcccaa cgaatgcagg aacaacataa
    29461 acctcatctt cgcttgtaga gcgtttcgct gcgtcttctg aatcgctagc tttttgcaac
    29521 atttgaagtc catctctcag ccattgaatc gaagaaccag ccacaaaaat acttccttct
    29581 aaagcatagt aaacctttcc atttatgccg taaccaattg tcgtcaataa attatttttg
    29641 gataattgcg gtttttcacc ggtattcatg acaataaatg aacctgtacc ataagtattc
    29701 ttgaccatgc ctggttcgaa tgccatttgt ccgaataatg cggcttgctg gtctcctgcc
    29761 atccctgaaa ttggtgcttc gcttccataa aaatgataac cttgcgtata accataaact
    29821 tctgagttag aagtgacttt tggtaacatc actcgaggaa tatttagtaa atctaaaatc
    29881 tcctgatccc aatctagctg atggatattg aacaacatcg tccgactggc attcgagtaa
    29941 tcagtaacat gtgcttgtcc atcggtcagt ttccatacta accaagaatc gatcgttcca
    30001 aacatcaatt cgcctttttc agctcgttct tgcgcgcctt ctacatgatc aagaatccag
    30061 cgtatcttcg ttgctgagaa ataggcatcg atcactaacc ctgttttttc gtggaaaaat
    30121 tcttgatagc cttcattttt taagttatct gcaattccag ctgactgtct ggattgccaa
    30181 acaactgcat gatagattgg acgtcctgta tctttttccc atattactgt tgtttcacgc
    30241 tggttcgtta tgccaatccc agcaatctga tttggtttga tccctgattc gatgaacgct
    30301 ccggcaataa ctgactgtac agaattccag atttcatttg catcatgttc cacccaactt
    30361 tcttgcggga aatattgcgt gaactctttt tgagaactgc cgatgtgtct tcctttcttg
    30421 tcaaagataa ttgctcgtga gctagttgta ccttggtcaa tcgccatgat atacgttgat
    30481 tctgtcattg tgattccctc cattatatgc aaacgctttc tttaactact cttatcatac
    30541 tactgtttta aaaaaagaaa ctgtcaaaat tttattcttt ttttcttttt ttgacagttt
    30601 tttattatga agctattttt taatcaattc ttttcttttt tcagcgtctc tattcttctt
    30661 ttcaatcgaa taatgtcgta aggtgacgca aattctgaca gataatattc acactgtttt
    30721 ttgtttctct ggcaaaatgt gatcaccaaa tcatattctt taccttcttc ataacttcca
    30781 atctcaatac cgccgattcc cctcagttct ctgatcagat attgttgaaa agcaatacga
    30841 taaatcggca gactttctaa atcgattcca atcactactg gttttgcaat ataaaaatcg
    30901 atcatcaaaa gaacattggc atactggatc atcaggtaac taagctcact atcttcagct
    30961 cttttcctcg gcaattgctg caccgctgtt tcctgtaatt tcgccagtaa ctgtgttaag
    31021 gaatgcccga gcattttctg ctgctgttcc aaaagccgat cacgctcata gacttcgatc
    31081 tttccaacaa agaaaaacca ttcattgttg atctgggaaa tttggtagcc tactgccttt
    31141 tcttctttga ttttcaaacg acgaggacga taatgccata acatcgtttc ccgaatgtaa
    31201 gtatctaaaa cagcggttgg taactttttg ctccgtgtca aatcatactg ataaaatatt
    31261 tcttcgtcta ctatcgaaaa agaaacaaaa aagctgtaaa acatcattgt ttcgtataca
    31321 ttcagttctg ctgctgttcg actaagatgc atcacgatga ttggatcgat tgcttgataa
    31381 agccggtccg actgatagag taatttcttt tctttcaaag ttgcgtacgt acttttttca
    31441 ttcaatagtc tttttttcgt aatcccgagc cagcaagcaa tctgtgcttc tgctgatgcc
    31501 gtaaacgttg tttctaatac acggtccaat cctagaatga acggtctttt ttctggtgta
    31561 ttttgcaaaa aaagcggtcg ctgatcttcc gggatatatt ggaatagttc ataataaaaa
    31621 tatcgtatct gtagctcttc tccgtataat tgaccgtttt tgatttgtaa tccaaattcc
    31681 tctaagagct ggttcaattc tttgatcttt cgaaaaacag aagactcact gatattaaac
    31741 gctgtcgcta atcgaacgat ggatacttgc tgatgttcta ataaatagac gagcatctta
    31801 aacttcaagc tttcctgcaa taaaaacaat agaatttttt ccaaacttac atcttcgtcc
    31861 aacacaagca gcgcctgata ctcatttcgc tgtacttcta cttttttttc catcattcgg
    31921 ccaatcaatt caatatcttc caaatattga tcaaacgagg cttttgacag ttggacatgc
    31981 tctctcaaac cattgataga ggctgttccc ccttgcagaa caaggtttcg caaaatcagg
    32041 atctgtaact gctcttttct ttctaataat gcttcaatct tcataggcag tattcgccac
    32101 ctttgaccac accatatctg gcacacggta ttctggctgg aaaaatagct catgttcttc
    32161 taactgttca aacgtccatc cttcttctac tgcaattgtc agttggtcaa gaaggtggaa
    32221 catctctttt ttgctttgga gctgtgctcc aagaatcttt ttttcagaat caaatagaaa
    32281 tttgagttta actttgcttt gatttattgc tgtaagcttg tagtctacgt atcctgtttc
    32341 aattttttgg ggataaaaaa tgctctcttc ttctgtcaaa cctacgcttc ctaagaaata
    32401 gccaaaccac tgattgccga ctggacgata ggttccctga tcctttgtct gtgagccact
    32461 aattgtcttg ctgacatttc gtgctgtacg gacagcgtta tttactagag aaacatacat
    32521 tttttcattt gttggacgaa aagttacttg gatcgcatcg ccaatcgcat aaacgtcttt
    32581 ttgagacgtt tgcaagtagt catctaccca gatcgttcca tcatcattca atgttaattg
    32641 ttcttcccac atctgattgt cgggacgaga atgattagcc agcaaaacaa gatcatagtt
    32701 ctcctttctt ttttccgtct ctacaatagc ggtttcattt tcggtcaaag acacaacttg
    32761 ttcttctaaa aaaagtgaaa gcccttgatt tttcatttcc tttactaacg gttctgtcat
    32821 ttcaggatct agataacgaa aaagaattga ctttcggctt tcgtaaagat ggatttgttt
    32881 ttttcttgat gccaaccctt cagctatttc gattcctgct tgtcctgcac caataattgc
    32941 aattttcttt gcattcatga tcttttgctg aagagccgtt acgttttgta tctttttaac
    33001 tgggtgaata agcgttgatt ctgcagaaat atttcgaaac ttttgatttg aaccagtcgc
    33061 tagaatcaaa cgatcaaaat ccaatttttt tcctcctgct aaaacgactt ttttttcttt
    33121 caatcctatt actgtctttt ctgtgtaaac atggattcga tagcggtcag tcagttcttc
    33181 tttcgtgatc caagaaagtt gtttttcact ggtaaccttt ccttttaata tcaaattgaa
    33241 cccgctggga atccatccta acttcgattg cttttcaatc aaatatattt cacttgttgg
    33301 catcaattgg cgaagataaa tagccgcatg aatccctgca aacgacccgc cgacaattac
    33361 aatgttcatc tgcattcctc tttcttataa ggtgttctac tgctaacttc tcaatcagaa
    33421 aacacagtat tcataactcg ctttcaacct tatgatacat agcgatgcag cagaatcaac
    33481 cctctccatc ataccgtgtt ctaggtctgc ttctcaataa tgtactagtg gacctaattg
    33541 aagagtatca tttctgaaga gatgtttcaa aaaatgtact cttataaaag aaaaaaactc
    33601 gccttttacg tacctctgtc caaataggaa acagaaaaga acgaaaagac gagttttagc
    33661 gtgtgtaatg taatagttag aatagacaca tcatttattt ttaattcttt aatgcttcaa
    33721 caactgcttc gcctaattga tgagcagatt gaggattttg ccctgtaaga agccgcccat
    33781 caatttgaac cacttctgaa aaagctgctc cagactgata gtttgctcct ttttctttca
    33841 aagcatcttc tgctaagaat ggtacttcat tcgttgtacc atttgcttcc tcttcttcat
    33901 tactgaaccc agtcactgta cgtccagcta aaatagattt tccagactca tctgtaactg
    33961 gcaacaatcc tacaacaccg tgacaaacag ctgagaccag cccttcattt cgatagattt
    34021 gtgaagcgac tttcccaaga tctattgctt ctggaaaatc ccacattgtt ccgtggccac
    34081 cagcataata aaccgctgca taatcatttg catccacatc atcaggacgt aaggtatttc
    34141 ccaaggcccg atttctgaaa tcttcatctt cataataggc ccaatcgatt tcatccatat
    34201 tcaaaacact ttgcggttct aaaggtacat atccgccttt aggactgaca aaatctgcat
    34261 cgatcccatt ttttactaat acatcataaa aatgagtcag ttcacttaac cacaaacctg
    34321 taggacgctc gatcttttcg tacttttcta catttgttaa tacgatcaat actttcattt
    34381 tcccatcctc tttctataaa aattgcgtta ttgataacgt gctttcaaga aattatataa
    34441 tgggcttggc aaataaagct ctttatatgc ttcttcaaaa ggtttcgtta caaattcatc
    34501 ctcacggttt tccaataatt tctctgccca gtcaggatcg acgatcattt gctgtccaat
    34561 tgctgcaagt tctgcatatt tcaatacctg ctctacatct tcgcgattgc ggatcccacc
    34621 gacaccaact aaagggatct ttccttgaat cgtgttatgg accacttcaa gaatcgattt
    34681 atcgttgtat ttatcagaac gagctattcg atcatacata tttaatgaaa catgcagata
    34741 atctagtttt gactcacgta atcgttcaag aagccagatc gtgtcttcaa aacggatacc
    34801 tggtgtttca tattcttctg gtgagaaacg ataccctacg atgaatggtt ttttagcata
    34861 ttgttcaacc gctgagaaaa ccgttgttaa taattcttca ataaaacgat aacgattttc
    34921 caagctaccg ccccattgat cctctcgtct attcgaatgc ggagagaaaa attgttggat
    34981 caaatacgta tttgctccat gcaactcgat tccatcaaat cctgattcaa tcgctctacg
    35041 tgtggctttg ccaaatgctt ggattgtttc aacgatttct tcttcactca ttgctcgtgg
    35101 tgtttccgca tcaggacgtt ttgctgcaac tgcacttgca gatacaggct gttctccaga
    35161 taaagttgct cgacttgtca ttcgtccacc gtggaaaatc tgaataatcg cttttgcgcc
    35221 ttctccttgg attgctttcg ctagctcact taatcgagga atcatttcat catgagcgat
    35281 gctgagttca cctggccagc cttttccgat atcttggaca tttgcagcac cagtaataac
    35341 agcaccaaga cctttagaac gttgtttata ataagtgatc tcatcttcgg tgatcactcc
    35401 attgaaaaag ctgagttgtg tcgtcatagg cgacagcatc aatcggttct tcaattgaac
    35461 tcctgaaggt aaagtaattg attgatcaaa ttgtgacatt gtcattcctc ccataattcg
    35521 ctctgattaa cctatcgaga atcatctatc attaaaccac tcgattagtt gtacatgcaa
    35581 ctaatttgct taaaaaattt tatttttttt gtaacttatc tgttgcatca ttcattgtct
    35641 gggctaattc tttacttgct tcatttccca aaactgcttt gtatgactga tgaagttctt
    35701 cccagctacc atcgacttcc ttagcaaatt ggcgtccttg ttctgtaaga taaactaatg
    35761 acaagcgacc ttcgctaact gttttgacgt atcctttata ttctaatttt tcaacaaaac
    35821 gagcaatcgt tgatggggcg gaatagagca tttgtgcaat atctttttgt ggtattccat
    35881 ctttttcttt taatatcaat aaaataaaac cataagttgg tgccagacct gtccttctaa
    35941 acgcttcatc agctaattta ttcaacatgc gatctagctt tttcacgcta aagaaaagac
    36001 attcatctaa cgctttttca attggctttt ccatttcatc ccctccattg gcgtacatat
    36061 catagtatga tttttatttt ttgtcaaaaa acacggaata atgtccgcct cctctgtcta
    36121 gatttgaaaa aaagaagtag ccatcttcaa agaatttcgg cttgttttcg acaaaactcc
    36181 ttctggaaca ccgtgaatca gaggttgtga aaaagtcgtt tagttttgag tatgaagaaa
    36241 aattttgtga aaatggcttt ccacattttt gcataaattt ggcttaatac cgaaaaactg
    36301 gcttttgaac accgtttata tcagaggttg tgaaaaagcc gtcctgcatc aagtaataag
    36361 aacagccaaa caaaaatagt tcctcatatt ttgtcgtttt ttgagctaat gccgatggtc
    36421 agctgattgt acaccgttta ttgagaggtc gtgagcctgc cgttgaactc cgagtcacaa
    36481 ggagcaattt caaaaaacag cttctcatgt tttatgacta tggtgacttg tgatcgagga
    36541 gttggcagga gaatactgtt tattcgtaaa gaaggggctg tgacaagact tttgtcacag
    36601 tcccttattt ccttttatta taggatttcg ccatttgatt ggatgacttg tctgtaccaa
    36661 tcaaatgatt ttttctttaa ccgtttcttt gtgccattcc cttcgtcatc ttgatcaaca
    36721 tagatatatc cataacgttt tgacatttgt gaagtagaag cgctgacgat atcaatgcag
    36781 ccccacgacg tataaccaaa taaatctact ccatctttga tagcttcctt catctgctca
    36841 atatgctgct tcaaatagtc aatgcggtaa tcgtcttgaa cggttccatc ttcttctact
    36901 ttgtctatag ctccgagtcc gttttcagct atgaacagtg gtttttgata cctatcatat
    36961 aattgattca aagcaattct caaaccctta ggatcaatct gccagcccca ttcacttgat
    37021 ggaagatacg gatttttaat tcctccagtt attaagtttc cttggacccc ttcccaattt
    37081 tctggatgag cactgactgc actagacatg tagtagctaa aagaaacaaa atcaacaggg
    37141 taggctgcta agatttcttc atcacctact tctattttta agttgacacc tttttcttca
    37201 aacattcgtt gcgtatacgc tggataatat cctcttgctt gaacatcact aaagaacaaa
    37261 gaagttcttt gctgctcaat tgttttttga atatcatccg gatcacaaga atacggaaca
    37321 agaagctgat agctgatcat acaaccgact tgtgaacctt tgataatttc atgacaagct
    37381 tttgtagcta aagcacttgc tataaactga tggtgtgcac cttggtattt cgcttgttcc
    37441 aaatggggat ggttttcttc aattactcct acgctaacaa aagggtgatg ttttacacag
    37501 ttgatctcat tgaaagtcat ccaatatttt actttatttt tatagcgttt gaatactgtt
    37561 tcagcgaaac gaacgtaaaa ctgaataagc tttcgattag gccatccacc atattctgta
    37621 accaaatata acggcatttc ataatgggaa agagaaacga ctggctcaat cccatatttt
    37681 agacattcgt caaacacttg atcataaaaa aataatcccg cttcattggg tgtttcttca
    37741 tcaccatgag gaaaaattct tgtccatgcg atagacatcc gatagcattt aaaacccatt
    37801 tcagcaaata aacggatgtc ttctttaaag tgatgataga aatcatttcc gtgtctttta
    37861 ggataataat acttgctgtt gggatcctgc gccgctttta cttgctgatg cgtcatcata
    37921 tgccattgat ctgtccattt ttctttaggt aaatcgctgt cgaatgtata cacatcagac
    37981 acagataatc ctttttcatc tacatcccat gcaccttcac attgattggc cgctgtcgct
    38041 ccgccccata aaaatccttc tggaaatttt ttcatatcga tccccctaaa cttgctagtt
    38101 ttcttgtttg attatttttc ttatgactag taatgatatt tttgaatcta ctactatttg
    38161 taacaataac cattgtggtc ggatcatatc cctctttgat taattcttgc aaatctactt
    38221 ccatcaataa atcgccttta cgtacttttt ttccatcaga tactgcactt tgaaagtatt
    38281 tgccatttaa attcactgta tcaataccga tatggatcag tatctctgct ccttcttcac
    38341 tgactacccc aattgcatgt ttcgttggaa aaactgttga aacttccccg tttacagaac
    38401 tgtagatttt tccgtccgtt ggaatgatcg caaacccttc tcctaaagat ccactagcaa
    38461 atgttggatc gtttacttca gataaatcaa ttatttcacc tgctgcagga gtacttaaca
    38521 ctatatcctt tgaggattct tcttcgattt catccttgta gccgaaaaga aaagttagca
    38581 tacaggaact gatcatcgct aagaaataac tagcaactag ccaaacaaat ccttcaccaa
    38641 tataaatcgg gaaagacaaa atacttcttg tagcaactgc caaagcaccg gctcctgcgg
    38701 caccagctac tccaccaaat atagctccac atatacaagc aatgtaaaat ggtcgtttat
    38761 atttaagagt cacaccataa acagcaggtt cagtgattcc aaataatgct gtgataaatg
    38821 cagataaaga taaacttttt actttcttat ttttcgtttt caaaaatacc ccaagtactg
    38881 ctcctgcttg cgcagctacg gcagtcatac atgctggacc tagcgtatca cgaccgtaga
    38941 aagaaagatt gttggtcatt actggtacaa gtccccaatg taacccaaaa atcactaaca
    39001 cttgccaaaa tccgccgata acagcaccag ataaaacagg gctaaagtta taaacagcta
    39061 aatatccagc tgcaatcagc tgacttgcat aatctgcaat tggacctaca actaataaaa
    39121 taattgggac catcacgatg atacaaatga atggtgtcaa taaatttcga atactttcgt
    39181 gcaagctttt gcgaatctta ggctcaatat aagaaagaac ccatacagct aaaattgctg
    39241 gaataaccgt acttgtatac cttgctagaa tcacgggcat ccctagaaat cgcaaggtta
    39301 tgctatcact atatgcactg acaatcgtag gataaacgag agctgctgca ataaccatag
    39361 cgatgaaacg atctgtattg aacttttttg cagcagtata tgccaaaaat ataggcaaga
    39421 aatagaaaaa tgcatcagct gctgcattca aaatgatata agttcctgat tcagtagtta
    39481 ataaattcaa actcgtacat aaggcgagta ctcctttgat caaaccactt cctgccaaga
    39541 cgcctaaagt cggggcaaaa acagcggcga tcatgtctat aaaagagttt aaaatgcctt
    39601 ttttctcagt tcctctcttt ccactagatg catcatcttc tagtttcatt tgtttggata
    39661 atacgtcata cacttcattt actgcatttc ctactacgac ttgaaacatt cctccagctt
    39721 cgactacagt gatcacacct tctagttgct ctaccttctc cttatctgcc ttcttattat
    39781 cttttagggt aaagcgtaac cttgttgcac aatggtaaac attgctgaca ttttcttcgc
    39841 ctccgacaaa tcggacaata tctttcgcta attgtgaata gtccattttt acttccccct
    39901 tgttaattaa tgccgtagca atccttctta caagataagt atagttctta gaaaacggtt
    39961 tctccattca attagtaccc cttctaatag cgaacgaaac tgtacaatag tgtgtatggt
    40021 ttacttagcc gagcaaatca ctcactgctt gaaagaaaac aagtatatcg tttctcttat
    40081 agtcaaagga gacaaaaaaa acacgcttga tcttcctttg ctgatgtata agtggtatct
    40141 caagctgata ctctgtgatt tttgtttcta cttggctttt gataagacag cacaacaaag
    40201 tctcggcatt taacggaagc ataactaggt cagaactagg agagattagt tgctgaatgg
    40261 aatctatctt tttatggatt tttatttgat tttcttcttt gtagtaatga tcaagcagtt
    40321 ttgttttctt tttttcttca actatggtca gcttttcacg caaaatctga taaatctccc
    40381 aagattcaaa ctcatctaga acactaggta gataaatcaa atcatcccac tcaaaaataa
    40441 gctcttgctc agtagtcaaa attgcatcat attccgttat tttgtttgat tgatttttga
    40501 aaagatacac tggttctatc cggcattctt tgatccacat gttcatactt tgttgaatct
    40561 gtttttttag tgtattcaaa atactaattg gctggttact aacaatcagt atctcccctt
    40621 gttttcgaaa aggattcaac gcttcggcaa gatacaaaac aaaataagcg ctttcagcta
    40681 aattgggacg taattgaaaa tgtattggga agaaacgccg aattaaataa atttctaaag
    40741 gataacggga gatgatcttt tgtacaaaat gattcatggt attatgtccg gcatccatcc
    40801 tcgttttcat ttgtttgata tgggttagca aaaattctgt ttcatggaac aataacgaaa
    40861 caggaagatc taaaaaacga ataatcgttt gctcaaatgc tcttagattc ttctctattt
    40921 ctttgttttt ttcatcatta atcatcaaat aatttaactc taatagtcga ttttcaattg
    40981 cttgtttttc ttgattggaa aaagaatagg gtagttctga tgataacttt tttgtgaggg
    41041 tctctaccat cggaataaat aatgtatacc tgtttgtttt ttctaaaagt tcttctcttc
    41101 gaagaatggt caaaacgaga taccgagaaa atcgtatgaa gtcctctcct gaaacaatat
    41161 aattatatga tataagaacc tcttttaatg tcttttggac agtcggcatg atattggaaa
    41221 aaattgtact gatttgttga ggaaaccttg cgtgttggat caccgtttct gttccaacaa
    41281 gagataagaa aattcttttt gaattttctt cagcaatgat ttttagtcct tttgtcgacg
    41341 aaacttccag ttctaattta ggattgcgct cgatccaacg caaaatcgtt tttatttgta
    41401 atgatacggc tgtttttgaa agaaagaaaa tgtctgctat cttttgcata ctgacatacc
    41461 ctttttgaaa caataagtac gtcacaatag ttgaagctcg gaaatccatg ctggaataga
    41521 ttttatgttt cgtcacctct tgtatgattt gctgtttagt ttcagattca attgattcta
    41581 aaaaataacc tgaacgttta tttgactgga taatgatttt cttctcgtag atagcaagca
    41641 tatttttgat ttcagtttgg atcgttttct tgttggtacc taaagcttca gctaattctt
    41701 cgcttgttat ccaatgattc ttatttctta atactacaag aatttggagt tgtcgtttat
    41761 ttaagtccat ttgcttacac ctcctctttg ttataaacat acaggaaaaa cctctcaaat
    41821 gacaatagtc acttgcagag gtttaaaaat catttgaaga aagatctata ttcaaggttt
    41881 ttaccattag actggataat ttgtttataa tattcaaaac tatctttttt caatctccta
    41941 aagcttccgc tcccatcatt ttgtctatcc acataaataa agccatatcg cttcctcatt
    42001 tcccctgttc ctgccgatac gatatcgatt ggtccccacc ataagtaacc aatgatttgg
    42061 caaccatctt ttattgcctc agcaatttcc tgaagatgta tttttagata ctcacaacgt
    42121 tttggatcgt ggattcgatt caattcatct ggtgcttcat ctagtccaat gccattttca
    42181 actatgaata atggtaattc ataacggtct gtcaattcat tcatgacata acgaaaccct
    42241 agaggatcaa ttggccaact ccaaggttcg ggagattttt ccttcaaaaa gggattatcg
    42301 aaaccatttg ctccgccagt atctacgcgc atttctgctt cttttttata gacagcgcta
    42361 cgataataac taaatgcaat ataatctgcc gtgttagctt gcaagcactg ttcgtctcca
    42421 tctaacatta ctggtgcaca gtcttcttcc ttccatgtcc tgtaaatata agctggataa
    42481 tgccctcggc acatgacatc ggagaaaaac catgaattgc gtttaaattg cagtgaacca
    42541 aatacattct ctggatcaca gtcatatgca taagtcgcta atgcagaaaa gctacacata
    42601 atacccatct tagcatttgg atcgattttc tttaataatt gagtagcacg ggcgttcgct
    42661 agaaacatat gatgacaggc ttgataaatc actttttttg ttagtgtagc aatgggttca
    42721 agtttatctc tagcagggaa tgtaaccaat ccagcagctg cataaggcat acgaaaagca
    42781 ttattgatct cattaaaggt catccaatat ttcactttcc cttggtagcg ttcaaagacg
    42841 gtctgcgcat aaaattcaaa aaagtcgatt aattttcgat tttgccaccc cccatactct
    42901 cctaccaatg ctaagggggt ttcataatga ctaagagtaa ttactggctc gatatcatat
    42961 cgatttaatg tattgattag tctgtcataa aatacgagac cagcctcatt tggcttctgt
    43021 tcgtctcctc ttggaaatat tcgtgcccat gagatgcttg ttcgaaaagc ttttaaacct
    43081 aactccttca gtaaacgaat atcctcttca aatcgatgat aaaaatcaat cgcttcatga
    43141 gaaagataat ggagtgattc gtctaaagca atctcccaaa tctttttttc ttcattccac
    43201 tgaatactag gatgctggtt catgatcccg ataagcgtat ctgtcacatt aggtaatttg
    43261 ccgtcttcca accatgcacc ttcacattga ttagcagcta ctgctccgcc ccataaaaaa
    43321 ttttctggaa atatttcctg atccataact atctctcctc gctatcaaca atttcttact
    43381 tgaagtatag ctcgattcat caaaacaaga tattctaact atttcggcag aagagaagaa
    43441 aaaaattgaa tgctactctt catttttaat atttatatat aacaaataca taagacgatc
    43501 cccgaaagaa aacactcgtt aaccatctaa gcaaacgatt tattttactt ccaacacaaa
    43561 tgcttcataa ggtcgtaaat caactttgcc gtctggtaac tgtttcagag gataatttga
    43621 cacaataacc cttaaagctt cacgtggaat agtgaacgtc tgcttttcac tggacatatt
    43681 acaaataacg agccattgct ggtcttcata tatgcgagaa taggcaaaga catgctcagg
    43741 cgtcttttcc actaattcat agtctcccca gacgatgatg tcatgttttc tacgcaaatc
    43801 gatcaatttc ttgtacatat aaaaaacaga atcttgatct gctaacgctt cttctgcatt
    43861 gatttcttta taatttggat tgactcgaag ccatggaatt ccagtagtaa acccagcatg
    43921 ttcacgggcg ttccattgca taggcgtcct agcattgtct cttcctttcg ccttgattga
    43981 ttccaagatt tcctcttttg taaatccaga agaaatcctt tcgttataca tattgattgt
    44041 ctcaatatct tttgcttccg cgatatcatc gattgggcaa ttcgtcatgc ctaactcttc
    44101 tccttgatag atataagggg tgcctttcat catatggagc aagatagcaa acatcttggc
    44161 actttctttt cgatacacat cgtcatttcc ccaacgagaa acaattcgcg gaagatcgtg
    44221 attattccaa aataaactat tccatccttc atcacctaaa gatgtttgcc atttggataa
    44281 tacttttttc agttcagaga tactcaaggg tttcaaatcc catttgtctt tgccttcttg
    44341 ctgatctaat cctatgtgtt cgaattggaa gaccatggat aattcatttc ttttaggatt
    44401 ggaataaagt ttagcgattt cggtagttgc tccccatgtt tcgccaacag tcatcagatt
    44461 tttgtcacca aaagttgctt gattcatttc ctgaagatac tcatgcagtt taggtccatt
    44521 acttgtgatt tctttatccg gttctttgcc aatcatatcg atcacgtcca tacgaaagcc
    44581 cccaatacct ttatcgatcc agaaattcat catttgataa atctcttggc gaacctgttt
    44641 atttttccaa ttcaaatcag gttgacgctt gctatacaag tgcagaaaat attgccccgt
    44701 tttttcatcc aactgccaag cagaaccact gaatattgag cgcaatctat taggctcttt
    44761 tccattgacc ggatcacgcc aaatataata gtcccgataa ggattttctt tatttttacg
    44821 ggcctcaatg aaccacggat gttcatcaga agtatgattc accaccagat ccatgatgat
    44881 acggatattt cttttctttg cttcttcaat cagttcttcc atttcttcca tcgtaccgaa
    44941 ttctgccatg attgcttgat aattactgat atcataccca ttgtcatcat tcggagactc
    45001 gtatactgga gaaagccaaa ttgcatcaat acctaaatac gccagataat ccaacctgga
    45061 aataatcccc cgcaaatctc caataccatc ttgatttgaa tcttgaaaac ttcttggata
    45121 gatttgataa acaactgaat ggtgccacca tttttgttcc atgattttcc tcctataaat
    45181 ggatgtttct attttttgct taatcattta ttttagtctc tctcactaaa aattgtaacg
    45241 ctttcaaata gctattgcac cttgttatcg gtaacagaat aaaacaaaaa aacagctgag
    45301 gaaattccct caactgtttt ttgaaaggat tgatttatgc agggaagaat gctgatttca
    45361 caacttcttt ataaacggtg ttcactcagc tgtcccttgg tattagctca aaaaacggca
    45421 aaatataaga aactattttt tcgttttttt ctctaatact caggccagaa cgctgatttc
    45481 acaacctctt tatttcacat tcaatatcca catgaatccc acaaatacaa agaacagacc
    45541 atacatgatt ggagatactt cttttcctct tttagctgct aacatggtaa ttggatagaa
    45601 gataaaacct aatgcaatcc catctgaaat actataagtc aaaggcatgc cgatcaagat
    45661 caagaatgaa gggatcgcaa tctctaagtt tccccattcg atttgtcgca aagattgtgc
    45721 catcaatact cctaccataa tcaatgctgg tgcagttact tgtgaagtaa caactgatag
    45781 taatggagaa aagaacaagc ctaacaagaa gaaaatccct gtagtaatag ctgtgatacc
    45841 tgaacgtcct ccaacggcga taccagctga tgattctaca aatgcaccaa caggagaagt
    45901 accaaataag gaacccgcaa gcatagctgt tgaatcagaa gctaaagctt tccctacacg
    45961 aggcatcttg ttgtctttca tgaaacctgc ttggtttgct aatccaacta aagttcctgc
    46021 tgtatcaaag aaagtcacaa gcaagaatgt cagcactacg acccacattt gaagagaatt
    46081 gatgtcccct acatgtttta atgcaactaa aaatgttggt ttcaaacttg gtgctgcggc
    46141 aacaatttca gaaggcattg gaatcaaacc tgtgaccaga cctaaaatcg ttgtagctgc
    46201 catcccgatg aagatgccac ctggtacacg ccgaacaagc aagatagcag ttacgactaa
    46261 tccaaaaatc gtcaaccaag tagaaccaac gttgagtgat cctaatccta ctaatgtaga
    46321 ttcattcgaa acgatgatcc caccttcgct cagaccaagg aaagcgataa atagaccgat
    46381 accgccagaa atcgcatatt tcaaatctgc tgggatcgca tcaatgatca tttcccgcag
    46441 cttgaagatt gtgatcaaaa taaaaatcaa agaagcaacg aatacgccgg ctaatgctgt
    46501 ttcccatgga atccccattc ctaaacaaac agaataagca aaaaaagcat tgatcccaag
    46561 agcaggtgcc gttccaattg gataacgggc taataccccc attaaaacac agccgatcgc
    46621 actggctaat gcagtcgcag taaacactgc tccttcatcc attccagaag cacctaatac
    46681 agttggattt acaaataaga tataagccat tgagataaat gttgtaaatc ctgccagtac
    46741 ctcacgtttt accgtggtgt tcaatttttc tatttcgaag taggaaagta ttttttcctt
    46801 catcttccat ccccctaaat ccgaacatta taaataaagt ccgttaaaat ttcgatttat
    46861 taataaaaca acgtgtttta tcatatacta aaacaaaaca taagtaaaca aaaaattcgg
    46921 attttaagca aaatccgaac gttccatctg attaaatccc tttatctcaa agttcatgaa
    46981 cattcacttt ggattacaag aatttcttta ttgtgttaat aaagtttctt cattctagtc
    47041 tcaaaaatca atagtgtgat ttgattttac catttcgttt ctgttcttct ttgatgaatt
    47101 cttttgtatc gacaggattc agattattta gtccgccaaa acctgtatcg accatttttc
    47161 cccagccttt tgtcttcttt tttcctgatt tgagattctt tgctcgaagc ttctcactat
    47221 gttttgctcg ccgatacttc aaataacctt ctaatcttcc cattagatcc actgtttttc
    47281 ctccttttta ttcaatcaga cgactcagct tttcctataa caaaataatt gccttcaggg
    47341 tcagaaaaat tgaaagtcaa gatgccattg ttatctgtga tttctcctgg ttcttccatg
    47401 ttctcgtaga tagtttcaaa ttcatccgta aaaaatacta aagaaggcgg tggtcctaat
    47461 acctctggtg aaaacttctg cacaaatact tttgggaata cgcctaattc taattctttt
    47521 gagatgctga gtacaatact cttaaattct tctggcaatt cgattgtttc agaaatttct
    47581 gcaccaattt tttctacaaa gaatcggcaa atcatctcta cgtcattgac ataaagcatc
    47641 acacgtgttt tttgtatcat catttgaccc ttctttctat ttgattttct ttcctgtcta
    47701 taaactgatt ccattatatc acgaaagcgc aaacaccttg tgtttgatac tattcaagaa
    47761 aaataaagca atagtttcta ggattgcttt cctccacaaa ctttttttac aaaaaaaaaa
    47821 cggcaatgaa tgccgctctt cttatttcga ttcttttata attctgcttc tgattcatct
    47881 ttggttagtg tgtgtctaac actagttacg ccaaatgttt gatcgatttt ttccttcaac
    47941 gcttcgattg cctgtgcgcc acgtgccgct tgttcagcat tgatggattc aatgaccagc
    48001 accgctgctt gtgtttcttc cgtcagcatc gttctttggg cttcacgcca gttgagacag
    48061 cgacagatcg ctccttgttc atcatagtag atgatttctt ccggaagtgc cggagcatcg
    48121 gaatctgcac ctaaaggcag gaatgattcg ccaccttggg cttttcctaa atgcagattt
    48181 cctgcgatct tttcgatatc ttctccgccg caaggtacgc caaaagacaa ggaaatacta
    48241 ttatagatat ctacaagcgg attgattggg aaaaattccc gttcttgatt tgcacgtttc
    48301 agtaaagctt caatagaaga acgtgcacct tttttagtct tgaatgtggt aaatgcctga
    48361 cgccactgag caatgacttc gttttggctg aatgtttctt ctgtaaggta atttcttgct
    48421 tcttttgctg cctcattcaa taattgatga tacgtttctt cactttcttt tgttacgtgg
    48481 ttatcgatac catttacgga taagatttcg atggttgctt caggaaatac ttcccagaaa
    48541 ttggtatcca ctattacttt tttcatctgt tcacacctct tgattagaat aattgcttga
    48601 tgaatagata gtctgtttgg ggatcatctc ccatataaaa aacatgttcg ctgtatttga
    48661 taaatccttt tttacgataa aaagcgagcg caacatcgtt gtgttcccaa acaccgagcc
    48721 aaatggctgt tttttgcttt tcttttgctt tttcaatagc tgtatctagt aaaaatgtac
    48781 cgataccttg atgtttaaat ttttttcgta catagattcg ctcgatttct aaaaaatgat
    48841 cagccatttc ctcagattga ctcgttcctg tatttagttt caggtaaccc gcaggctctt
    48901 gatcgatact cactaggaaa aaatcggttt ctttatcttt tagctcttct gtaagttttt
    48961 ctagtgcata agcttgtgtc aagtaatcag ctaaatgctc cggtgaatta tcttttccaa
    49021 atgtatctgt aaatgtttcg atactaattt gttgtagtaa gtctacatct gaaggcgtca
    49081 tttttcgaat ttcgtattta ttcacggctt cttcctttca atagatcctt ttattgcctt
    49141 ttttgacaaa attccaatct tcgctaacat tcttgcatac tttatttaaa agatattcca
    49201 attgttttgc ttcttcgtca gaaagaccat ttaatgcgac tgcattggag tagttgtttt
    49261 ctcgaatgat gaaaggatag atttctgctc cttttttagt cggatagagt ttcttgattt
    49321 ttttattttc tttatcttcc aaacgttcga tcatcccatt ggattctaat ttcttgattg
    49381 ctcgggcagt cgttgtacga tctactttga tcatttctgc tagtttttct tggatgattc
    49441 caggattttc gcaaatacgt actaaataaa gatactgtcc tcttgttaaa tcgacttctt
    49501 tgaattcgat attgctaata gaatctagcg ctcgggcaat cattccgatg tctcgaagga
    49561 tttcagccat ttcatcccac ctttattttg tttgtaagac tagttcacct ctttttgttg
    49621 caaatgcaac tattttcaat aaaaaaatca agttcttttt taataactag taaagtatat
    49681 tcttttcttc ttttacgaaa aagctcaatc acaatagatc tggtttttgt tttctaaaat
    49741 aagtaactgt ttcttcgttg ttcgcttttc tgatagcttt ggcaactctt ctatactaaa
    49801 aaatcccatg ttggaagttt cattattctc aataaacttg gcctcttcac cgtggatcgc
    49861 acaagcaaaa acaagtttat aatactgaaa aagctgtgga atatcttttt gtttattcgt
    49921 atcaaaaact gctcgcaact gagtagtttc tactgttaat cctgtttctt catagacttc
    49981 tttacgcaca ttttcttcag gagacaatcc tatttcagca aatccaccag gaagtgacca
    50041 ttctttcgtc cgtttatctt cgattagtag gaccttgcca tcttttttga tataggcacg
    50101 aacatctact tttggtgttg gatgtccttc tccaatcgtt gtgagcgctt ttatttcttc
    50161 gaaagtttct tttcctattt cactgatcag ttccaatgaa atcgtccgga tctcctcaaa
    50221 acgctcttta tcaaatacat cttttccata atatagacca gcttgagaaa gtgcgagtag
    50281 tcttttgtat tgagccaact tcttgttcat tctcttccct tcttttttag caaatgtatg
    50341 actatgtaat caagtataga agactggttt aattacggca aataaatata atgaaatctg
    50401 caataaataa aagaatgtta aaaaactcga gaacaaaaga cattcgactt ctctggggct
    50461 gtgaataaat ggcgttcaaa agcttgcatc tgcggtaata agccccacca aacgaaaaat
    50521 atgacgagct attcttgtct ggctgttctt attaattgag gcaggacagc tttttcacaa
    50581 cctccccact aaacggtgtt ctcctaccaa ctcctcggtc acaagtcaca atattcatca
    50641 aacatgagaa gctgtttttt tgaaattgct ccttgtgact cggagctgaa cgacaggctc
    50701 acgacctctc ggtaaacagc gttcaaaagc caatttttcg atattaagcc atttctttgt
    50761 tacttattgt cattgatttc tttttctaat ttatccaata gtggagtgta atccacttga
    50821 gtatagtctg ttacatcaaa ttcatatagt gttcctaact ggaatttgtc atattttcgg
    50881 tcggcgatga tctttttgaa tgcttctttc gtaatatgat tggtcccttt cgttcgatct
    50941 tccaatacgt caccatagtg ataatgatcc atgatatagc tcaaatgacg atctgattca
    51001 cgatcacgtt tgtaccgacg ttgccataac acttcaaagt ctgctgttag gcgaatcgtg
    51061 atcacctgat atccgtatct atctgctaat tcttggagtc gtgctttttg cttatcacta
    51121 aaaggatact cggacacaat cactttcttt cctgcttcca tatacaaatc aagtgctttg
    51181 taatagaaag gataaacttt cgtcctttct tgttccgccc gttcttccaa attgttaaac
    51241 ccgatggatt ctgcatagta ttccttgatt tcatcgagcg tgatggcata catatctgga
    51301 aatcgttccc gtagtttatt cataagatat gtttttcctg taccaggact accagccaga
    51361 agaatgaaat actttttcat ctcatttatt tcctaagtta attggacttt ccaagttcat
    51421 aaacagtcca atcttatgct tgacaatttc ttttactgct tcatttgctg gaatcacatt
    51481 atggcgaaga gacttgttga tttctgtttc actaaaggtt tctttagcta ctttcgtcca
    51541 gttgactaaa agctccgttc caacattgaa tttgcggatc ccgttattga tcaattcagg
    51601 ataatcttct tctttcacac ctgttcctcc atggataact agggggacat caactactgc
    51661 atcgatttct ttcagcaagg gaatgtttac ttctgttttt gatttgaatt gtccatgatt
    51721 cgtaccgata gcaatagcta atgcatccac gcctgtagct tctacaaatt tcactgcgtc
    51781 ttccggtctt gtatatacct tgtcattttc agcgacatgg attccttctt ctgtaccgcc
    51841 gattgttcca agttctcctt ctacggaaac accgtgcgca tgggcatatt ctactactgc
    51901 ttttgtcttc aggatatttt ctttgaaagg cagatgggac ccatcataca tgacagaagt
    51961 atatccgctg tcgattgctt ctttgatatc atcaaagtct cgggcgtggt ctaagtgcaa
    52021 gactgcatca accatttctt cttctgcaat agctgtcatt acattgacta acacatgcat
    52081 gccgatatat ttagcggtat cgacacttgt ttgaataatg atcggcgaac ccatttcttt
    52141 tgctgcgcct agcatagcag gaagcatttc taggttatgc gtattaaaag ctccaactgt
    52201 aaaattcaac tcttctgctg tttttgttac ttctttcaat gttgtataca tcttttattg
    52261 ccaccttatc tttttatttg tttcctttga tcgttacttg ttttgcaatt tgtcgcatct
    52321 catccatttt gcccatgtag taatcgatcc cttgatcatc accagcacga gcagcatctg
    52381 cacgcttctg gttatagagg ctcatcagtt ttttataccc atctccgatc gtctgtttat
    52441 tttccaaact cttttctaaa tattggatgg cttgatcgtt cacatacaat tcagaaaatt
    52501 taagtccaac ttgttcataa agtttcgcta atttatgctt atcttgggta gtggaaatct
    52561 cttgtttcaa ttgtgtaatc tctgattgaa tcttttcggt cgcttctggc gatagggctt
    52621 tttcttcttt tgccagaact tttttcggtt ctttttcttt tttcttaaaa aatccaaaca
    52681 tcattttccc tactttcaat taaaatgctt tcaaaactgg gcttaagatc caggcatata
    52741 agagtgctgc ggctactgta tctacatcgg ttgctgtagc attgttgaat cccatcgaat
    52801 taaagatcgt tactagcaaa gcgggcaata atgtaataaa gaaaccatga gcaataccgc
    52861 caatgatcgc tcctcggcgt ccgccaactg cgttgccaaa tatccctgct gtccctccgg
    52921 caaagaaatt ggttagcata ccaggtaaaa tcatcgctaa gccgaacatg ggcaaagtaa
    52981 acatggcaat aatcgtacca atcgttgtcg taatgaaacc taaaatgaca gcatttgggc
    53041 tataaggaaa gaaaactgga caatctaagg cagggatcgc atcaggaact aatttcatag
    53101 ctatccctcg aaatgccggc acgatttcac ctaacagtag acgtacacca gctagcaata
    53161 catacacacc cactacgaat tggatggctt gtaaaaaggc aaacatgata tagttttgat
    53221 ctcctgataa ttcagaagcg aatggttcgc ctgcaaataa aacagtgatg atatatagcg
    53281 ggaccatcac gaccatgaca gacaaataag tatcttgcag aaattcgaaa tgtgtcggca
    53341 acttgatatc ttcgatcgac tttttatttt cgcctttctc accaaaaagc ttagcaacac
    53401 cggcttcaaa taagtacccg atcgtacaaa aatgacctaa agcaatatca tttgatccag
    53461 tgattttacg aatgatcggt tgcgctactg ccggcatagc aatggcgaaa caagctccga
    53521 taaaaccacc gaccaagatc aatacgatcc ctcgcagacc ggcaaaatag ccaaagactg
    53581 tcgtcatcgt tgccatccat aaaattgctt gaccagttaa aaaaatgtac ttccattttg
    53641 tgaaacgagc caaaataata ttgaatacaa aaatggctaa gaacgtcagt gcaatatctc
    53701 tacctaaacc caaatcattc attgcttgac cattgataga ttcaatagaa gggatgatcc
    53761 cttgcatatg aaatccttca gtaaagattt tcccgaaata agttaaactt ccaacgatga
    53821 tgctcgaacc ggcactcaac acttgaaatc ctaggagtgt ctttaacgtg ccagagatga
    53881 cttgtcctgc tgatttcttc tgcagtagta gacccaacat agcaatcaat gcaatggtga
    53941 tcgatgcctg agtcaaaata ttttcgatga taaaattgat aacgcccatg tttttaccct
    54001 cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga ttttttcttc
    54061 aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag gatcaactgc
    54121 gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg gtttcatgga
    54181 aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt tgttcaaaac
    54241 atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc atacgaataa
    54301 aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct caactactga
    54361 aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat ccaacttctc
    54421 ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt aggagtctac
    54481 tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga aatcgattgg
    54541 ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg gtcgggcatg
    54601 ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca ctgcacgaat
    54661 catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc tagcagctag
    54721 ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc tgtccgtcaa
    54781 aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt ttgtttcgaa
    54841 taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt ctttcatgac
    54901 atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta accgctgtag
    54961 ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag ttaaaatcgg
    55021 atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga aaaccagatt
    55081 gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag taatctcgat
    55141 ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca tcccatggtt
    55201 acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac tggcgatcgt
    55261 cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac caattacttc
    55321 ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat ttgttcggat
    55381 gttttctttc aatggattca tgacttggat atgattcttg attcttacaa tcagtgcagc
    55441 catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag gtacgtgtgt
    55501 ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta cccactcgat
    55561 tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat aatttctttc
    55621 tacttgcggg acattgtcca attgaaattc ctcgatcatg tggtcaataa atgcagaaaa
    55681 gctactgtct tttatttctg tatttttcca attaatggca gagataaatt catgtttcct
    55741 gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa tatcatcttc
    55801 ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca ccaaaggaaa
    55861 ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca taaagaagtc
    55921 ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag atcgttctga
    55981 acctttataa accagtcctt gctttccata actgacgatc tctatcccat aactgaccag
    56041 tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt gaaattcttc
    56101 ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa ctagatcaaa
    56161 aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag tttctaatcg
    56221 agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg tacggatctc
    56281 cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac ggatcgtccg
    56341 ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt gggctgtcat
    56401 gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct tctgatttca
    56461 agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga agtggaaaga
    56521 aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca acgaaaaaga
    56581 catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt gtgaaaaagc
    56641 tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat ttttcgtttg
    56701 gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga ggttgtgaca
    56761 gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc atattttaca
    56821 aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag aaaaaggagc
    56881 tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc cagcataatc
    56941 ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa ataccatatc
    57001 tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc ttttcgatcg
    57061 actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc gtggatctgt
    57121 cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac accgtctgct
    57181 ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata acagcttctg
    57241 gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat cttttggatt
    57301 tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa tatctccgct
    57361 ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac ccctcctact
    57421 gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc tgtacctgga
    57481 ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact gcccccatat
    57541 gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc tccaccatga
    57601 ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc cactaacaaa
    57661 atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta ttacaaaaaa
    57721 ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat aaactgtttt
    57781 tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat gtgtcggcag
    57841 tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct gcgcttcctc
    57901 caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga cgatttggta
    57961 aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt ttctgatcac
    58021 tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac atatgcattt
    58081 gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca agcctgatat
    58141 gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt tgcttcaccc
    58201 tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca gcaagcttgc
    58261 tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt ttttgtgcaa
    58321 tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg atgccatttg
    58381 tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt tctcttaact
    58441 cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa ggagttagcg
    58501 tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc gcatccagtg
    58561 catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct tcctctacca
    58621 acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg acactcactc
    58681 cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg atatgaagta
    58741 accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga atcatgactc
    58801 ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg aaaacaaata
    58861 cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat ggcaattttg
    58921 gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg atgactaaac
    58981 tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag tctcctggat
    59041 gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt aagaaaagat
    59101 aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg gctaccccat
    59161 aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga taaggcccag
    59221 tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt gaaccaatca
    59281 atactggcca tacatatttt ttattagcaa atactttgta accgagccaa acaaaaaacg
    59341 gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc gctccatcac
    59401 ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt tgttggactg
    59461 ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact agttcaaaaa
    59521 acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc atattataaa
    59581 caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag gtaccaagaa
    59641 aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc gtttgcatca
    59701 taacagccgt tacagctgat actttctgga agtcacttac gttgattttg atttttttgt
    59761 tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg ttaatttagg
    59821 tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact cttttagtga
    59881 aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag caggatgcga
    59941 ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca aatcaaaatc
    60001 actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc tgccgccgat
    60061 tccccattta catcctgata atatgtttct agcagcatga aattgctgat aaacaggata
    60121 atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg gatgaatgac
    60181 ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg caggtccacg
    60241 taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg ttccgaacat
    60301 cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat gtttatcaaa
    60361 aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt ccattttggc
    60421 acggacttta tttgtttcga cacgtccgaa tgttttggct gtttcgtttg tgtatcgatt
    60481 tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga ttgcttcgat
    60541 gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta ggaaatgata
    60601 gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa ctttttcagc
    60661 agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt ctttagacat
    60721 cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt gtaatccatg
    60781 tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg gatgtccagc
    60841 ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga taccgatcaa
    60901 ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga ttggccgttt
    60961 cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca tgcggaaacc
    61021 ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag gatcaggtac
    61081 gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat acacagtact
    61141 aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt aaccaacact
    61201 tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt ttgcttgatg
    61261 gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat ctaaagaatc
    61321 aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc gttcgtccat
    61381 tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt catcaatgat
    61441 ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt tgtcactaga
    61501 atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca aaccgactct
    61561 cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca taccgccaaa
    61621 tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta gagcaatgat
    61681 tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca aacgaacacc
    61741 acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt cttctaacac
    61801 atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc caccttggaa
    61861 ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac ggctgacaac
    61921 gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg cgatgatttg
    61981 atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc gttctctggc
    62041 gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc gtcaatcgta
    62101 ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct gaaattggat
    62161 aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca tcgcttcctg
    62221 tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt tccaaatctc
    62281 ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt ggatatttat
    62341 aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca cgttctgctt
    62401 attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc gccaatttta
    62461 tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt cgatcaaatc
    62521 atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga tgcctagatc
    62581 ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt tcgtgctagt
    62641 cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt cttcttttgt
    62701 ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag tatcttcgct
    62761 ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta gtgcatctaa
    62821 ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt gaacaactaa
    62881 tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg ctggtgtaga
    62941 atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac cagataaacg
    63001 tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg aaccgataaa
    63061 catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc gcatcgtgcc
    63121 gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca taccaacttc
    63181 gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa tcatcgttgg
    63241 atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg attcaccata
    63301 agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat tcaaagattg
    63361 tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa tttgcaattc
    63421 tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt tatctgcttt
    63481 cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat cgacaacttc
    63541 gttaacttga acgatcacga taccatcttt gaaagctgca gcttcgatga ttgttggtgt
    63601 ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat ctgcagctac
    63661 taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca aataagtatg
    63721 gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca agctttgtgc
    63781 accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat tcaaatgttc
    63841 tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg catctacttt
    63901 ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta atacaacttt
    63961 gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt ctacatactt
    64021 gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc gtttagaagc
    64081 ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata gaaacgtggc
    64141 gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta caccaaattt
    64201 tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca gatccattcc
    64261 taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta ggttttccaa
    64321 caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat tttttatata
    64381 caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt tcttgaccgt
    64441 atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg ctgtttgcgc
    64501 ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc cagataacgt
    64561 atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat caaatgtttt
    64621 tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca ttgcataacc
    64681 gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg ctgcattctc
    64741 aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat gtcctgctgc
    64801 aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg cttttgtcag
    64861 taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa ctaaccgata
    64921 ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta acatccctaa
    64981 cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg cctcctcagc
    65041 acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat gccaaaaaaa
    65101 gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg cttcatctgc
    65161 agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa gaattattta
    65221 tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta ggtgtccctt
    65281 tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa ttttatccat
    65341 atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct tcggtcaatg
    65401 agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct attccgaact
    65461 tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg caacatcatt
    65521 taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag cctggcatga
    65581 ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa catcctcttg
    65641 ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg atgctgtcaa
    65701 agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt atcgaattga
    65761 cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag caaggattag
    65821 ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct ttcgtcttgc
    65881 gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc ttcacagaag
    65941 atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta ggaaaataaa
    66001 aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa cggtgttcca
    66061 gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc aattttcgta
    66121 aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc tattgtccta
    66181 gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc atctagcttt
    66241 tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata ggctggaaaa
    66301 tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa atcaagaata
    66361 ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac agacatcagg
    66421 accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg aaatttttta
    66481 aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag ttcttttttc
    66541 gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat accacgtaag
    66601 aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt cttttttatc
    66661 aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat taaaatgttt
    66721 attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag ttcatgatga
    66781 aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa tcagttgaaa
    66841 cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga ttgatgtatt
    66901 cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct ttagtagaac
    66961 aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata gggacaaccg
    67021 aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa ggctgggaca
    67081 tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta acaaatgacc
    67141 tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat ctgcttttta
    67201 caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat gggacattga
    67261 aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag atcgatttga
    67321 cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt tatcatcgat
    67381 tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc catgaatccc
    67441 attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa acagaagaga
    67501 ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat tgccgattag
    67561 attcttctat ccataccaac agcacactct cctccctgta tgactctgca ttgaaaaaat
    67621 tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct tctttctgct
    67681 ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc tgcctgcatc
    67741 attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca gagctgtctc
    67801 ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata ttaaaatatc
    67861 atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt ttagaaacat
    67921 atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac gatctaaaaa
    67981 aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta ctgatccaac
    68041 aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc caaggagaac
    68101 cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa cgtgtctgct
    68161 tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca gatatcttga
    68221 tttccaattt ccctctagat tctctagata tccctattgt atacatttct tctattccaa
    68281 cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aactttttta tagtaacggc
    68341 tagcgactgt attctctagc tgttttttct tttttgcgaa acagtttgtt catgatccct
    68401 ttttctattt ctacaactaa gaatagaaga atcacatttg ctccaatcaa taactgttgt
    68461 gtcatcgtta aacttactgt accgatcagc tgctggccga ctggtagaaa aataaccatc
    68521 ccttgcaata aagcaaggat acctaatgaa agaaaaagcg ctttgttttg caaaagacct
    68581 tggttcaatg acggcttgga caactctctg caattgatca tgtaaacagc ttgagctaag
    68641 acgatatttt gcagaagaat ggtttgctgt aagctttgcc cttcaaactg catagccaat
    68701 aaataggcag gaaccatgat cagtagggag acatagatga tccgaaacaa atgataacca
    68761 gataggattc cttgctttgg atctcttggt gggcgcttca tgatttctgg atctggcgac
    68821 tcgaacccta gtgcataaga taaagtgatt gtcgttacca tattgaccca taaaatctgt
    68881 actggggaca aaggtagcgg gcgattcagc ataagtgccc aaatcaagat caatccttga
    68941 gctaatgcag ttggcaagaa gaaattgatg gttttttgca aattatccaa aatccgccgg
    69001 ccctctttta cggcttttgc aatcgtatgg aaattatcat ctcctaaaac catatcagct
    69061 gcctgtttgc ttacttcact acctttgatt cccatagcaa ttcctacatc ggatcttttc
    69121 aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc atttttctgc
    69181 aaagctttaa caattcgcag tttatgttct ggtgtcgttc gagcaaagac atcgactatt
    69241 ggcacttgct gaatcaactc ttcatcagac ataagatcca aatcgatccc ttctaaaact
    69301 ttggcagtat gttttaagcc aatttgttcc gcaatcgctt ttgctgtgtc tttgtgatcc
    69361 cctgtaatca ttttcactga gatccctgct tgttggcatt cctttacagc tttgactgca
    69421 ctttcttttg gcggatcgat caatccggcg atccctgcaa aagttaattg ggttaaagtc
    69481 tcatgcgtga gttcctgttt cgaatctact tttttataag caaatcctaa aacacgctga
    69541 ccttttctcg caaattctgc agctgtctga ctccatgctt cttgttctgc agaagaaaga
    69601 gttgatttag caaataatac ttctggtgca cctttgacgt aaatcaccgc tcctttttcc
    69661 tccgcatgca tcgttgccat atatttgtat tcagaactga acggaatctt tgcttctatt
    69721 tttttcaaag gtagattggc tgtttctgtg tgtcgaatca gcgcaacttc tgtcggattg
    69781 ccacttaaat tttctgtttt ctgttcttct tttgttttta attcctgaca gtttttcata
    69841 atggacaaca cgcaggcttc ttcttttgca gctacatcca caactgtcat ttcatttttt
    69901 gtcaatgttc ctgtcttatc tgaacagatc actgtcatag aacctaatgt ttctaccgaa
    69961 ggaagtcctt tgatgatcgc cttttctttt gccatttcat gtactccaac ggatagaatc
    70021 atggtcaaaa cagctggcaa tccttcgggt accattgaca ccaccaaagc aatcgtagcc
    70081 gaaagaagaa tatgccaatc cataccatat cgaaatgtcg taaaaataac taagaatagg
    70141 ctcaaacaaa gaatgccttg aaaaatttgt ttgtttaatc ggttgatttt tttaatcaga
    70201 ggcgtcgttt gttgttcgac cgattgcaat gcttgattga ttttaccgat ttctgtcgtg
    70261 tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt tcctgaaaaa
    70321 cccatatttt tctggtcgcc gatcgattct tcttctgtca aaacggcatg acttttttca
    70381 gatgcttctg attctcccgt caaaatcgat tcttccacta ataaatcatg tgcttcgatt
    70441 aatcggatat ctgctggaac gacatctccg gcacgtaaga caatgacatc tccttttacc
    70501 agttctttcg cagggatttt ttcttgcatc ccgtttgata gtactatcgc ttcttgtccc
    70561 atcagctgct tcaaaccatt caatgattct tccgcttttc tttcttgcca gtaactaacg
    70621 agtccattga cgatcactac gaataaaata atacttcctt caatatattc actagaagca
    70681 aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa atgctttgct
    70741 atttttttcc atcgttttgt ctgctgcctt gcttttattt cattatatcc ttgatcagtc
    70801 aggcgtttct gtcgttcttc ttgcgacaag ccttctgttg atgtttgata gtttttcaat
    70861 acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta attgatactg
    70921 ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg tctgaaataa
    70981 ttcgttttgc aaaatgtatc tgggcctaac tgatatttct attgcttatt cttttatata
    71041 caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt gtcgtgcttt
    71101 cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga tctttatatc
    71161 tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac aagatcgaag
    71221 accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa aacaatcgac
    71281 tatcagctac aaaaaaatgt agacaaagac cggcaaaaaa taacattcct gtaattaaaa
    71341 taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc aaactttttt
    71401 cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt gctgaggaca
    71461 aagaagcaac caaaatcatt agattgacaa ttgctgctcc gccttggcaa tggatcactt
    71521 gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga acaacaaata
    71581 aaatcgacaa aatcgttcct atatagaaaa agagaatacg ccaaggcaga cagttgattg
    71641 cttttttcaa attcttttgc ggatcacttg tctcgccaac ggttaagccg atcatttcaa
    71701 ttccagcaaa actgaataaa accataggaa atgagactac cattccagca aagccaaacg
    71761 gtagtaattc atcgatctgt ccaaaatttt ctttgattcc gatagactgg gtatgaaaat
    71821 ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag atcttgatga
    71881 ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg actgccatta
    71941 agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac cagaaatgga
    72001 tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa agccaataag
    72061 tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa tcactgatag
    72121 agttaaatgt actatttgct aaaaataaat cacccatggc ccgcatcaaa ccataaatag
    72181 ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca attgcctttg
    72241 ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac tggatatttc
    72301 gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt ttctttttca
    72361 agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat acagagtggt
    72421 actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca tgttccagct
    72481 ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac gacagtccaa
    72541 actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt caactttgca
    72601 tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat acagtagata
    72661 acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat cagcaaataa
    72721 aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt ggatacgtca
    72781 aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct agcactttct
    72841 gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac accaatgaag
    72901 acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg gcaataaatc
    72961 gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac atttgctaca
    73021 actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa tactccgcga
    73081 atatacgttt taactggatt ttccaatcga gtgatataca cagaggacat ttcgatacca
    73141 gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt agtatctggt
    73201 attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc aactttgatc
    73261 cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc taaccaaaca
    73321 ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt gatgatccaa
    73381 taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg cacattatcg
    73441 ataatattac caaacaacgg agcgagtgct gaagcgacca tcaccatccc aggaaacatt
    73501 tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc attcgatacc
    73561 caaagttctg gaccaccttt ttggggaaac attccagcaa attcaccaga gatcaatgag
    73621 attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt ccagctcgtt
    73681 gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat tccgataaag
    73741 gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc ttctttcaat
    73801 agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga caaggtttca
    73861 tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt agtgaactgg
    73921 gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa gaatatcttg
    73981 gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca aataattgtc
    74041 tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt ggatgatttc
    74101 gtttagtttc ttttccattg ctttggcgat tttttttgta taaaaattga aaattcgatc
    74161 atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct gttctttttt
    74221 ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat caccgtaatc
    74281 ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat cgccatccat
    74341 ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca aatctgtaca
    74401 gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca atggatagac
    74461 ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc tgaatctttg
    74521 agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca atggcaatac
    74581 acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt ccaaaatata
    74641 agctcctaac atatctggag cctttactga tttttcaaac acatatggcg cgaaataaga
    74701 aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat aagggacata
    74761 gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc tgaacccttc
    74821 atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt caaagaattc
    74881 agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg aacgcgcata
    74941 gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt ttaacctttc
    75001 tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg ttcctacgac
    75061 agcaaccaca cctagaattg ggattttttg tccagctaat tcacgaattg ttttttccaa
    75121 agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct gatctaagcc
    75181 gactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag ggaccagcca
    75241 tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga cctcatccat
    75301 ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata aattcaaaag
    75361 ttcccactca gacatttttt tcactttttc aggcagcact tccttgacag ctaaaggaat
    75421 cgatttgatg caacgggcgt accataatcc ttcaagatta gcaatagaac catctgctgc
    75481 aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc ctacttctgc
    75541 ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt tccacagcat
    75601 cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt gtccccagta
    75661 acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga cttcatccaa
    75721 gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat ctccttcgct
    75781 aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt catctaccat
    75841 cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta taaagacggc
    75901 cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa tgtcttgcag
    75961 atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga attttttttt
    76021 tataacatca aatccacgta gatttttaca aacaaaaata aataaagtcg gatttttctg
    76081 ataattcaac gcaaaaaagc gaacaatttt tcaataaatc agtcttctaa aatagataac
    76141 ctaaaaaaag cgaacaaaca aataaaatga ctgtccttca ttcactaaac atatttttat
    76201 ttttttatat tgttaaaaat tcgcaattta ttttttaata gaattatctg ttttccaaat
    76261 tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa attaactgat
    76321 gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa tacaaggcgg
    76381 aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc tgtttttatg
    76441 tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc tcctgcatgt
    76501 ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg aagaacagat
    76561 cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac atatacctcg
    76621 atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt gtctgcttta
    76681 tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca tctctgtcag
    76741 caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg ggatcgaaat
    76801 cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc ttaatgtgtc
    76861 gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg aacgtgccga
    76921 tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag aaaataaaga
    76981 aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg ctgtgacaat
    77041 agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg tcgaatcagc
    77101 atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct ttattttgac
    77161 actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg aagactttca
    77221 acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag ttgctacctt
    77281 tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg cgctgattca
    77341 tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat tttatctttt
    77401 aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca gctggtccag
    77461 ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg tgatcgaatt
    77521 gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca caaattcgga
    77581 tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg attttcaagt
    77641 tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc agtcctcaaa
    77701 ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg aaaatattat
    77761 tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa acaaataagg
    77821 ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat ttctgtaaca
    77881 atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac gggtccgatc
    77941 tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc tagttggaaa
    78001 atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac aagaatttcc
    78061 aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc gctgactcgg
    78121 tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat tgatagacaa
    78181 acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag tttttcgaaa
    78241 tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt ctttgttttt
    78301 ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg ataataataa
    78361 gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg atatcagcaa
    78421 cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt gtatctgcat
    78481 tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa agtttgaata
    78541 gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa atagcaatga
    78601 tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac tttcttttaa
    78661 tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt aaaagttgtt
    78721 ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc tccctccatc
    78781 cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt agtccgtcat
    78841 cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc taaaaataga
    78901 accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta caggaaaatc
    78961 agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca tttggcattc
    79021 taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt ttttcatgag
    79081 taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg ctgcatatct
    79141 aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat tcgaatcaat
    79201 ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg aggaatcaca
    79261 atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc agcggctgtt
    79321 tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc attggatgat
    79381 cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg gaataaaaac
    79441 catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct taattaccgt
    79501 acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga gccagggatg
    79561 actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga caaagcacgt
    79621 ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa taataaagac
    79681 cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa actagacaat
    79741 atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa cttctggttt
    79801 atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt gcgtcgctat
    79861 atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt caatcgaaca
    79921 cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa agaacaagga
    79981 tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac accgatgcaa
    80041 gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga agaagaatac
    80101 gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac agattcagct
    80161 actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc agcttctagt
    80221 ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa attctttgct
    80281 gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca tttgttgttg
    80341 aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc atttatttca
    80401 accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctatcgt cgtgcatcat
    80461 caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta tttcctttat
    80521 ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg aaaagaaatg
    80581 ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa tattcgtgaa
    80641 aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat gccttatgct
    80701 tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc taaacattcg
    80761 accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat ctttactgaa
    80821 caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat tcctatgtcc
    80881 cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg tgccgcaaaa
    80941 aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt aataagaaca
    81001 accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc gcagatgcaa
    81061 gcttttgaac accgtttacc aagaggttgt gaaaaagctg ccctgcatca agtaataaga
    81121 acacccaagc taaaactgct tcttatgttt ttgacttggt tggacttatt accgcagatg
    81181 caagcttttg aacaccattt accaagaggt tatgaaaaag ctgccctgca tcaagtaata
    81241 agagcagcca agctaaaaca gcttcttatg tttttgactt ggttagactt attaccgcag
    81301 atgcaagctt ttgaacaccg tttaccaaga ggttatgaaa aaggcgttta gtttcgagta
    81361 tgaagaaaaa ttttgtgaaa atggttcctc acgtttttgc ataaatttga cttaataccg
    81421 agaaactgat cccttctgtc ataacctctt tttatttatg tctgtttctt tttgaaaaca
    81481 actatttttt caacgtttac tctcttgcca atccaacatc atctaacgga tacaactatt
    81541 tcaatgatta ccattacact aaaaaatcgg aaacacacct ctccgaacac aaatacataa
    81601 gactatagaa tgtttcattt aagaaaaaaa gcgtttcatt atcaaaaagg taagatctcc
    81661 tttaaaatga aattatctgt agtactaata atgcagacaa ttttatgaat ctgaaaggag
    81721 catctccaat gaaagcagtc acttggcaag gaaaacagaa aatggaaatc agaaacgtag
    81781 atgatccaaa aatattagaa ccaacagatg caatcatccg tatcacagca acagccattt
    81841 gcggctccga tctgcatctt taccatcatg gtgaagcagt tttggaaaaa gggtatgttg
    81901 taggacacga accaatggga atcgttgaag aagtgggatc tcaagttcaa acattgaaaa
    81961 aagggcaacg tgtggttatc ccttttaata ttagttgtgg tcattgtcat ttctgcctga
    82021 atcacatgga aagccaatgt gatgaatcaa atccagatca gttatatggc gggcttttcg
    82081 gatttggcaa gttgaacggt aatcattggg gtggtcaagc ggaatatcta agagttcctt
    82141 atgcagactc tacttcattt gttgtaccag ataatgatct tcctgatgaa aaagttttat
    82201 ttctatcaga tattttgccc acagcttatt ggagcgttga aaacgcagga gtaaaaaaag
    82261 gcgatacagt tgtgattcta ggttctggtc cagtcggtct attcgctcaa aaattcgctg
    82321 ttatggctgg agcagagcgc gtaatcgcag tagatccagt acagcaccgt ctagataaag
    82381 cggctaatta caatggggtt gaaacttatt tcttagaaga cacggcacaa gctggaacag
    82441 aattgtatga actggctaaa ggtggcgcag atgtcattat cgattgtgta ggaatggacg
    82501 gattagagcc tgtcaaagaa aaagcgaaaa atttagtaag cttacaaagc ggcacaatct
    82561 ctccattaca gatggcatcg caagctgtca aaaaatttgg aacagtccaa gtaactggtg
    82621 tttatatgac tccagcttct tcttacccgc tgcaagaatt ttttatgcgg gatatcgctg
    82681 tcaagcatgg acaggcacca attatccatc taatgccaaa aatttacgca atgattgcag
    82741 aaggactatt cgatcctaca caaatcatta ctcattcgct gccactatca gaagcagcac
    82801 aagcatatga gatctttgac aaaaaagaag ataaaaatat aaaagttgtt ttgaaacctt
    82861 gaattcagta aaaaatacag gtgattttct ttatgcccaa aatcaaacga aatacccatg
    82921 agatcgaaat aggaaaagaa gaagatatcg aaatacgagg acgtcgcttc cgcttctatt
    82981 tccaaaatcg ttacacattg atctcactgg ctgtcgattt attaaccggg attttctata
    83041 tttttggaag ccttgcttcc ttaactaaaa tccccgatcg atatggcacc tatttttatt
    83101 tggctggtgc tattttcttg acgattcgtc ctattctcag aatcgtaagg aacattttta
    83161 tttacgacga aaaaaaagca atgaagagaa caagcaaaaa aaaagaggca tgagaatttt
    83221 tcaaatctca tgcctctttt ttcaccctat cgtatcactt tgatacagac gagcggtcgt
    83281 cccactttct tccttgacca ttgtcaaaaa tgtccactcg tatcgttcat aaaacgtggt
    83341 atgatctgta attaagtaaa gtttttcgta cccaagttga tgcatttctt ttctgatttc
    83401 cgctaatatc cgcttggcta tcccctgctt acgcttttcc ggttcaacaa acagggcaca
    83461 aagatttggt gtcagatcag ggcggttatg gaagtcgttt tcaatgacgc ccgctcctcc
    83521 gacgatggtt tctttttcat ctaagaccac ataccattga ggaatacttt ccttattagc
    83581 gattccagta cgaatacttt cctcatacac aacagcagga actccccatt ttgatgaaaa
    83641 ccaattcgcg ctttgtttta ctaattctgg gtgttctctt aatttgatcc agttatatgt
    83701 aaccaatgtt taaacctccg actaaaataa aacgtttaca aaaattatac aagtctttat
    83761 gaaaattagc aatgacaaca atagtgatgt aaaaaaaaaa cggaaaacaa tcacttgttc
    83821 tccgtttttt gattaatcaa gcatctaaag cttcttttct tctttcttgg atcgtagcta
    83881 ccttgacgaa cggtagatag atcaaaatag aaagaaccaa attgacagcg gctagtacac
    83941 cacctgcaat actttttgtt gccaatacac cgccaataat tggtggagtt acccatggag
    84001 gcataacggt agctgctggc actaaacctg tagaagtcgc aaagtaagca acactaacta
    84061 agaccattgg tgtcaaaata aatggaatga acatgatcgg gttcaacacg ataggtaacc
    84121 caaacatcgt tggttcatta atattgaaga cacctggcgc aatcgacaag tttgttacaa
    84181 ccatatatgg tttgttttta cgtcctacta aataaatagc taacagtaaa cctaaagttg
    84241 cacctgttcc tcctaagttg acaaagctgt caaagaaagg tttgttcacg ataaacggtg
    84301 cgctatgccc agctgcgatt gcattaacgt ttgcttcaat ggctggcgca ttgattgttt
    84361 gcatcaaagg atcgaccata ttcgctccgt gtaaaccaaa gaaccataag aatggtgtga
    84421 taaatgcaag cagtaaggca gatggataag agtttgcaag tcccataaat ggttcttgga
    84481 ccactgtata gaaagaacct acgatatcat caacaccgaa tgcagcaaaa attgcagcaa
    84541 ctaaagcaaa cgcagagata gtgatcattg ctggtagtaa tgaagcaaat gcttttgcaa
    84601 ctgccggtgg cacaccatca ggcattttga tgatcaattt ttcatttccg cttaaacgta
    84661 caaagatttc tgttgaaata atcccaacaa taatagcaat aaacaaaccg tttgagctca
    84721 tacctaatgc tccgcctaaa gcgaagaaag agcctaaaga aatcacacct gcggaaacac
    84781 cgtcttttcg gtagccgtta gctaaatgat aagcaagcaa gaaagcaatc aagacagaaa
    84841 gaatggcaaa tgtaccgttc caagcagcag ccccgaatcc tttccatgat tcaccaccaa
    84901 aaattgagtt catcaattct tggaacccgg gaatcggtaa gttattgatc attactgcta
    84961 atgctcctaa gatcattaac ggcatactca ccataaatga gtcccgaatc gcaactaaat
    85021 gccgttgtgc accaattttt gatgctacag gtataaaatg tttctccata aatgcaacaa
    85081 atttatccat aaatcttccc tcttttcttt actgtagatt acgcgttcaa tcgacgatac
    85141 agatcaatga tctcttttgc taaatctgta aaagctatag atgtcatcag atgatcttga
    85201 ctgtggaccg tcaaaagcgt gacttcaacg tgatttcctt gtgcttcttg tgtcagcatc
    85261 tctgtttgag agtgatgtgc ttggactaaa gattcctctg catctttgat tttttcatct
    85321 gctaaagtga aatcaccttt tttcgcagca gcaatcgctt ccattgcatc gctttttgca
    85381 tttccgccaa acatgatcag acccatgatg gcttctagat ttttttgatc ttccatttat
    85441 tgtatcctcc gataattttt attatttgtt tattagtttt tctgcttggt cgagtacttt
    85501 ttcaccattc atcatgccat agtcagccat attgattaca tctaaaggaa tgcctttagg
    85561 tgctagcttt tcagcaaatt gattttgcat aaagcgtact tgcggtccta aaagtaaaac
    85621 gtctacattt ttagattcta gttgattatc cgcatctgaa gcagatacag caaagatgtc
    85681 tgcttccatt ccttttgctt ctgctgcctt ttgcattttt gtgactagga gacttgtact
    85741 cattccagct gaacatacaa gcatgattgt tttcttttcc attttaaaca cgttcctttc
    85801 tatacttaca cttgtatata agcaagtagc gtgccaactt taaaagcgct ttaaaaagtt
    85861 gatatcatca catttaaggt ctataccaag ttgcatacac actaaaaaag aaagcgcaca
    85921 ctaaacacac aaattaattt ttattacctt ttttctttta acgtgcacaa aaaaagttgt
    85981 gacacaaaac ttgtcacaac ttttttcaaa taaacggtat tcaaaagctt gcatctgcgg
    86041 taataagtcc aaccaagtta aaaacataag atgttgtttt tactttgcta ttcttattac
    86101 ttgatgcagg acagcttttt cacaacctct caataaacgg tgttcaatca gctgaccctg
    86161 ggtattagct caaaacgctg gattcacaac ctcttttatt tcaaataacc agtaaataca
    86221 atgaacatct acaaaaaact tctatttatt tatagatttc gtcaggcaaa tccaattctc
    86281 tcttatcaat caaagtctga taccacgaag cagatttttt caatgttctg cttcgttcat
    86341 cgttcaattc gattcgaact aatccatatc gattcttaaa tgcattcatt ggtgacacac
    86401 agtcagtgaa tgcccataac atatagcctt cgcaatttgc gccttcttct gttgctttga
    86461 tcaagtaatg caaatgctgt ccgataaatt cgatacggta atcatcttgc acgattcctt
    86521 tctcatccat atactgttct tcatattctc ttcccatacc gttttctgtt atcagccaag
    86581 ggatattatg ataattttct tttagataca tggctatatc atacatgatt ttcggataga
    86641 tttcccatcc cctggaatta ttcattttct tcccaggtaa atcaaagact tcataatatc
    86701 gttcaggatg gaaaggtgtc tcttcattcc attgataacg aggggcgcga acgcgtttag
    86761 gataatattg attgattcca aggaaatcta ctgtatgatg ctgaatcgtt tctaaatcct
    86821 ctgttgcagg atcgaaataa atcgattgtt tttgacacaa ctccaggaac tcttctgtgt
    86881 agtatccttt taccatcgga tcaaaaaata ctcgattata aaacaaatca tacatataag
    86941 cagctttttg gtcttctgga gaattggatc gagcatagac catttcagga tttaaaatac
    87001 agccaatcct tccaccataa tttccgctgc ggtaaatctc tactgcttta gccgttgcta
    87061 aaactttatg ataattccac atcatccact tttttgtgtt ttgttcatgc ggccagcgaa
    87121 cagcatccaa atagcaacgc gtttggggaa cgattggttc gttgaatgta aaccagtttt
    87181 ttaccctatc accgtaacga tcaaaggcaa tttgagcata cttagcataa aaatcaacta
    87241 cttttcttga agaccagcca tcatattttt ccaaaagaaa agctgggact tcataatgtt
    87301 ccaaacaaat catcggttct acgtctgctt cgatcaaaga gtcgatcatt tcacttatat
    87361 gctgagcata ttcttcatct actatacagt tctcataatc agtaaaaaaa cgagcccaat
    87421 tgatagaagt ccgataatgt gtcagatgga tggatttcat cagatccaca tcctgctggt
    87481 attgttccat aaaattagtt gctacggctg ggccataccc attatgccaa acaaaatgtt
    87541 catttttata ccagctatct ataaacgaat cctgtccttc tttttttcct ttccaacctt
    87601 ccgtttgcca agcagaagat gcagcaccaa gaataaaatt ttttggaata gtaattttca
    87661 tgatttcctc ctgtttttta gatcccatca ttttccacac gatttgctac ttttacaaat
    87721 ggcagataga tcaaaataga aacaataata caaacaagtt gcgtaataac tgcaccgata
    87781 tttcctgctg ttgccagata agcattgacg atcggcggca ttggccaagg gaccattaca
    87841 actgctttcg ccgcaaatcc taaagcggtt gcaaaataac caatcgttcc agtgataaga
    87901 ggcgttaaga taaacggaat agctaaaatt ggattcagca tgatcggcat accaaaaata
    87961 actggttcat tgatgttgaa gatcccagga gcaagggata acttggtgat ttgtttcata
    88021 tcttcccgtt ttccaactaa caatactgca atcagtaaac cgatcgtgac tccagacccg
    88081 cccatactca tatacatatc ccaaaatggc atagtaataa tgttcggtac ttcttttcca
    88141 gcttcaaaag cttccgtatt tacagcaatt gccgctaaaa gcaacggttc ccgtatcggc
    88201 ttcaccattt gatttccatg gataccaatc acccaaaaga cttgcgcaat aaacatcaat
    88261 agcaaaatac ccggtaaccc ttgtacgaca ccttctaatg ggcgttgtac gacattgtaa
    88321 atgatatcat aaaggtacat tcctgtaagt tctttgatga taaatcccgc agccgcgata
    88381 cccgatacag tcagaatcgt cgggaataaa gcagaaaaac tagcagaaac attcgttggc
    88441 acggtatcag gcattctcag ctgtagtttc ttctgtttcc tcaaccagca ataaagttca
    88501 atagaaagga tggagaccaa cattcccaaa aataaccctt tcgtatctgt atattgttta
    88561 gccaatacgt tttctactat aacagtctga ttttcattca ctaattcata aacagttgga
    88621 ttaacagata aataagacat cactgcgatg ataccaggga atacaccatc cactttattc
    88681 agcttggcta attcgatccc tatcagaaaa acagcataga tggtcaagaa acttagtgtg
    88741 acatagctga tggcagatgc gataggcttt aattcttcta aaaaacgcaa gaaacttatc
    88801 tgtgctaagc cattttccga gtcaaagacc attgctgaaa acaatgtgcc aaaagcaccc
    88861 gtaataatta ccggaatcaa tgcagcaaat gcgtttttta tcaccatgat ataccttaaa
    88921 ttattgattc tcgttgccac gttccctaaa acattggcta atttatccat aaaactcatt
    88981 ccagatcccc tcattcctgc ttcttctcct tgacgtcatc tctttttgtc tattagtcag
    89041 cgcttacatt tcgatgaaca gaaactattt actcctcttt tttaccaaat ataaaacaaa
    89101 aattcatctg atgtatttat cataaaatac atcagatgaa ctgtcaatta gtttcttttt
    89161 ctcctattat tttctgtaat tctctccgat ttattgccat atggacagtc attgcatcaa
    89221 acgcagcaag tgcattccgc ctttcgatgg cctgaacgat ctctgtatga atatcgatcg
    89281 tctcgatttt cagatgctgg atatcataat ttttattaaa caaagcaatt gattcattaa
    89341 tgattgggat aatatgcagc aaggctacgt ttccgctagc ttctgcaatc atcgtatgaa
    89401 aatcgatgtc taattgaaca tgttcttgtg tgccttctcg aaaagaagtt tcaatctttt
    89461 gcgttaattt tttcatttgg acgatttgat tcttcgttgc atattccgct gccaaacctg
    89521 ccatcttagg ctccaataaa tatctcagtt caaataagtc tcgtatcatc cgatcctgat
    89581 cttcaatcaa agaaaaaccg agtgggtcat tggcaatccc tcgcttatca ctgacaaatg
    89641 tccccgctcc ttgccgaact tcaaggatat tcctggaagc tagagcccgc acagcttctc
    89701 gcaccgtgct tcgccccacc tctaaataat cggacaattc atattcattc ggcagtttat
    89761 ctcctacttg caactgcatt tcctttaaat atctaaggat cttgtcagta gttacttcta
    89821 ctagggtttt attttcttcc aaaccacata cctccttttc atctgatgta ttttttcgta
    89881 attattataa cacgtttgaa tcatctgatg attttttgta tacaaaattg attaatccgt
    89941 tcatagacat acaaacgaag aagatattta ccataaaaaa gactaggata aa
//
LOCUS       DAIGWC010000003        73272 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.003, whole genome shotgun sequence.
ACCESSION   DAIGWC010000003 DAIGWC010000000
VERSION     DAIGWC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.003"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(89..1648)
                     /locus_tag="NOB74_000200"
     CDS             complement(89..1648)
                     /locus_tag="NOB74_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HCI1219413.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            1803..4037
                     /gene="pcrA"
                     /locus_tag="NOB74_000201"
     CDS             1803..4037
                     /gene="pcrA"
                     /locus_tag="NOB74_000201"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HCI1219414.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            4054..6090
                     /gene="ligA"
                     /locus_tag="NOB74_000202"
     CDS             4054..6090
                     /gene="ligA"
                     /locus_tag="NOB74_000202"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HCI1219415.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            6196..6501
                     /gene="gatC"
                     /locus_tag="NOB74_000203"
     CDS             6196..6501
                     /gene="gatC"
                     /locus_tag="NOB74_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HCI1219416.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            6501..7973
                     /gene="gatA"
                     /locus_tag="NOB74_000204"
     CDS             6501..7973
                     /gene="gatA"
                     /locus_tag="NOB74_000204"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HCI1219417.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            7970..9400
                     /gene="gatB"
                     /locus_tag="NOB74_000205"
     CDS             7970..9400
                     /gene="gatB"
                     /locus_tag="NOB74_000205"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HCI1219418.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            9410..10465
                     /locus_tag="NOB74_000206"
     CDS             9410..10465
                     /locus_tag="NOB74_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCI1219419.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            10576..11949
                     /gene="rlmD"
                     /locus_tag="NOB74_000207"
     CDS             10576..11949
                     /gene="rlmD"
                     /locus_tag="NOB74_000207"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCI1219420.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            11952..12080
                     /locus_tag="NOB74_000208"
     CDS             11952..12080
                     /locus_tag="NOB74_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCI1219421.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            12520..12708
                     /locus_tag="NOB74_000209"
     CDS             12520..12708
                     /locus_tag="NOB74_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HCI1219422.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            12786..13799
                     /locus_tag="NOB74_000210"
     CDS             12786..13799
                     /locus_tag="NOB74_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1219423.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(13866..14900)
                     /locus_tag="NOB74_000211"
     CDS             complement(13866..14900)
                     /locus_tag="NOB74_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1219424.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            15015..17240
                     /locus_tag="NOB74_000212"
     CDS             15015..17240
                     /locus_tag="NOB74_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCI1219425.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            17258..19141
                     /locus_tag="NOB74_000213"
     CDS             17258..19141
                     /locus_tag="NOB74_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HCI1219426.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            19122..20096
                     /locus_tag="NOB74_000214"
     CDS             19122..20096
                     /locus_tag="NOB74_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HCI1219427.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSRETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            20755..21777
                     /gene="aroF"
                     /locus_tag="NOB74_000215"
     CDS             20755..21777
                     /gene="aroF"
                     /locus_tag="NOB74_000215"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HCI1219428.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            21810..22874
                     /gene="aroB"
                     /locus_tag="NOB74_000216"
     CDS             21810..22874
                     /gene="aroB"
                     /locus_tag="NOB74_000216"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HCI1219429.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            22876..24042
                     /gene="aroC"
                     /locus_tag="NOB74_000217"
     CDS             22876..24042
                     /gene="aroC"
                     /locus_tag="NOB74_000217"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HCI1219430.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            24059..25150
                     /locus_tag="NOB74_000218"
     CDS             24059..25150
                     /locus_tag="NOB74_000218"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HCI1219431.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            25163..26458
                     /gene="aroA"
                     /locus_tag="NOB74_000219"
     CDS             25163..26458
                     /gene="aroA"
                     /locus_tag="NOB74_000219"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HCI1219432.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            26451..26960
                     /locus_tag="NOB74_000220"
     CDS             26451..26960
                     /locus_tag="NOB74_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HCI1219433.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            26957..27793
                     /gene="pheA"
                     /locus_tag="NOB74_000221"
     CDS             26957..27793
                     /gene="pheA"
                     /locus_tag="NOB74_000221"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HCI1219434.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(27856..29592)
                     /locus_tag="NOB74_000222"
     CDS             complement(27856..29592)
                     /locus_tag="NOB74_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCI1219435.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(29589..30518)
                     /locus_tag="NOB74_000223"
     CDS             complement(29589..30518)
                     /locus_tag="NOB74_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1219436.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            complement(30518..31096)
                     /locus_tag="NOB74_000224"
     CDS             complement(30518..31096)
                     /locus_tag="NOB74_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI1219437.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            31369..32655
                     /locus_tag="NOB74_000225"
     CDS             31369..32655
                     /locus_tag="NOB74_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1219438.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            32792..33661
                     /locus_tag="NOB74_000226"
     CDS             32792..33661
                     /locus_tag="NOB74_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1219439.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            33658..34545
                     /locus_tag="NOB74_000227"
     CDS             33658..34545
                     /locus_tag="NOB74_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1219440.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            34712..35395
                     /locus_tag="NOB74_000228"
     CDS             34712..35395
                     /locus_tag="NOB74_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCI1219441.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            35392..36165
                     /locus_tag="NOB74_000229"
     CDS             35392..36165
                     /locus_tag="NOB74_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCI1219442.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            36162..36560
                     /locus_tag="NOB74_000230"
     CDS             36162..36560
                     /locus_tag="NOB74_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HCI1219443.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDEKNDREKSES"
     gene            36745..37416
                     /locus_tag="NOB74_000231"
     CDS             36745..37416
                     /locus_tag="NOB74_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219444.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            37475..37915
                     /locus_tag="NOB74_000232"
     CDS             37475..37915
                     /locus_tag="NOB74_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219445.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            37927..38595
                     /locus_tag="NOB74_000233"
     CDS             37927..38595
                     /locus_tag="NOB74_000233"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCI1219446.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            38659..39282
                     /locus_tag="NOB74_000234"
     CDS             38659..39282
                     /locus_tag="NOB74_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HCI1219447.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            39338..39724
                     /locus_tag="NOB74_000235"
     CDS             39338..39724
                     /locus_tag="NOB74_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HCI1219448.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            39937..41328
                     /locus_tag="NOB74_000236"
     CDS             39937..41328
                     /locus_tag="NOB74_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HCI1219449.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            41939..42307
                     /locus_tag="NOB74_000237"
     CDS             41939..42307
                     /locus_tag="NOB74_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HCI1219450.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            42487..43428
                     /locus_tag="NOB74_000238"
     CDS             42487..43428
                     /locus_tag="NOB74_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HCI1219451.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            43497..44228
                     /locus_tag="NOB74_000239"
     CDS             43497..44228
                     /locus_tag="NOB74_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HCI1219452.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            44372..46552
                     /locus_tag="NOB74_000240"
     CDS             44372..46552
                     /locus_tag="NOB74_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HCI1219453.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            46572..47054
                     /locus_tag="NOB74_000241"
     CDS             46572..47054
                     /locus_tag="NOB74_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HCI1219454.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            47070..47831
                     /locus_tag="NOB74_000242"
     CDS             47070..47831
                     /locus_tag="NOB74_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCI1219455.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            47962..49296
                     /locus_tag="NOB74_000243"
     CDS             47962..49296
                     /locus_tag="NOB74_000243"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HCI1219456.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            49603..50088
                     /locus_tag="NOB74_000244"
     CDS             49603..50088
                     /locus_tag="NOB74_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HCI1219457.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            50081..50764
                     /locus_tag="NOB74_000245"
     CDS             50081..50764
                     /locus_tag="NOB74_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HCI1219458.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            50890..53535
                     /gene="polA"
                     /locus_tag="NOB74_000246"
     CDS             50890..53535
                     /gene="polA"
                     /locus_tag="NOB74_000246"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HCI1219459.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            53580..54416
                     /gene="mutM"
                     /locus_tag="NOB74_000247"
     CDS             53580..54416
                     /gene="mutM"
                     /locus_tag="NOB74_000247"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HCI1219460.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            54380..55009
                     /locus_tag="NOB74_000248"
     CDS             54380..55009
                     /locus_tag="NOB74_000248"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HCI1219461.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            55061..55393
                     /locus_tag="NOB74_000249"
     CDS             55061..55393
                     /locus_tag="NOB74_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCI1219462.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            55705..56196
                     /gene="nrdR"
                     /locus_tag="NOB74_000250"
     CDS             55705..56196
                     /gene="nrdR"
                     /locus_tag="NOB74_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HCI1219463.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            56219..57592
                     /locus_tag="NOB74_000251"
     CDS             56219..57592
                     /locus_tag="NOB74_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCI1219464.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            57592..58518
                     /gene="dnaI"
                     /locus_tag="NOB74_000252"
     CDS             57592..58518
                     /gene="dnaI"
                     /locus_tag="NOB74_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HCI1219465.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            58647..59087
                     /locus_tag="NOB74_000253"
     CDS             58647..59087
                     /locus_tag="NOB74_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCI1219466.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            59231..59932
                     /locus_tag="NOB74_000254"
     CDS             59231..59932
                     /locus_tag="NOB74_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HCI1219467.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            59929..61050
                     /locus_tag="NOB74_000255"
     CDS             59929..61050
                     /locus_tag="NOB74_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HCI1219468.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            61065..62297
                     /gene="pepT"
                     /locus_tag="NOB74_000256"
     CDS             61065..62297
                     /gene="pepT"
                     /locus_tag="NOB74_000256"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HCI1219469.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            62429..63337
                     /locus_tag="NOB74_000257"
     CDS             62429..63337
                     /locus_tag="NOB74_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HCI1219470.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            63372..63644
                     /locus_tag="NOB74_000258"
     CDS             63372..63644
                     /locus_tag="NOB74_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HCI1219471.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            63655..64701
                     /locus_tag="NOB74_000259"
     CDS             63655..64701
                     /locus_tag="NOB74_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HCI1219472.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            64952..67561
                     /gene="clpB"
                     /locus_tag="NOB74_000260"
     CDS             64952..67561
                     /gene="clpB"
                     /locus_tag="NOB74_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HCI1219473.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(67712..68398)
                     /locus_tag="NOB74_000261"
     CDS             complement(67712..68398)
                     /locus_tag="NOB74_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219474.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(68376..68870)
                     /locus_tag="NOB74_000262"
     CDS             complement(68376..68870)
                     /locus_tag="NOB74_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCI1219475.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(68890..70110)
                     /locus_tag="NOB74_000263"
     CDS             complement(68890..70110)
                     /locus_tag="NOB74_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1219476.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            70257..72092
                     /gene="lepA"
                     /locus_tag="NOB74_000264"
     CDS             70257..72092
                     /gene="lepA"
                     /locus_tag="NOB74_000264"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HCI1219477.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(72186..>73272)
                     /locus_tag="NOB74_000265"
     CDS             complement(72186..>73272)
                     /locus_tag="NOB74_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1219478.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNTVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        24142 a        13100 c        15787 g        20243 t
ORIGIN      
        1 ttttcccagc ctcttctttt tttatagaat catatagaat caagtagtgt agatgaatag
       61 ttgttgtaaa atagtttttc catgttcgtt aaaatgattg cttcaaattt gtgatagaag
      121 atttagcctc gatttcctgc ttgattcttg gcaagtttgc ttcatcagtc aagataacca
      181 aaatatctcc tacattcatg atcgtatcac cgtgagtcaa gatttcctga tttcctctgc
      241 gtatagagat tagcagcata tttttaggcc aattgaagtc tcgtaccatt aatccgtcta
      301 aagaactctc tgccgttact ggaaaatcaa aagttgtcct tgcacctttt agtgaggcgg
      361 tctgagtatt tccaagtaga cgttccaata atgattcgta aattggatta ccgccgagaa
      421 ggtcattgac gatataagca acaagagcag ccaatcctaa aggcatcaga tgattaagag
      481 agccaaccat ttctgtcact aaaataattg ctgtcagcgg tgcttttcca atcgctgtga
      541 aataaccagc catggcaata acgacaaaat ccttgatgta gattggatcc atcccgaaat
      601 caaccataat gtttccataa aagctaccga ttaaagcccc caatgtcaat atcggaagga
      661 aaatcccccc tggaagaccc ccaccgtaag aaatcatgga aaaaacgaat cgaagaacaa
      721 acaaaccgat aatcataatg attggcaagg aagcatgtcc aaaagctaaa acgatttgat
      781 tgcctccgcc tagagtacta ggccataaat aaccaattgg caaaatcagc aagaaaggaa
      841 cgaacccgtg aaaataagct ggtaaaggca atcggttgta aaattttggc aaagccagca
      901 agacattctg ataaataaaa cctaagatgc ctagaagtac tcctaagatc actaaggaac
      961 cataatattt caacggcaaa gaaggaaggt cacctagata taaaacaggt ctcaagccga
     1021 aaaagtaaag agagacgaag ttagcagtga ttgctgaagc aaatgatgtc agccaaacaa
     1081 gtggagaaaa ggagtgatgg atttcttcta aaacaaagag taatcctgcg ataggagcat
     1141 tgaatgctgc tgcaagtccg ctacttgcac cgctagaaat taaaatcttt tcttctgaag
     1201 atggactccg aaacaattgt ccagctcctt gtccaatgga tgcgccaagc tgtatagaag
     1261 gtccttctct acctagaaaa aggcccgcac caactgaaag tacaccgcca atgaactttt
     1321 tccataaaac agagaaccag ttcattgata attccccgcg aagctgtccc tctacttgtg
     1381 gaatcccgct tcccttgata tccggttcat ttttgaccag ataacccacg aaaaatgctg
     1441 caaggatgca gcaaatagct aggccaatta agtaaatcgg ctgttcccga ctcatttcat
     1501 agatacttcg aactaaatcg cttagctttt cgatagataa tcgaaacagg ctaacgacga
     1561 ttcctgtcag cagtccaaca aatattcctt ttagaataaa atatatctga gtcttatcta
     1621 atttcttgat ttttcctttt ttttccattc aaacgcctcg ctttctttta atttagcgcg
     1681 aaatcaacga attgacaagg aaaaatccat aaaaagaaac aaatgatttt gaactagcta
     1741 gtttaatgaa agccaagaaa atgctataat taacaagatt gataaaagaa aggatgttgt
     1801 taatgtcatc caaagctgaa ttattaaacg ggatgaaccc ccgtcagaaa gaagctgttc
     1861 ttcacactga cggaccatta ctgctaatgg caggtgcagg aagtggaaag acgagagtgc
     1921 tgacacaccg cattgcctat ttgattgagg aaaaagaagt caatccttgg aacatcctag
     1981 cgattacttt taccaataag gctgcaaaag aaatgaaaga acgtgtcaat gcgattctcg
     2041 catctggagg cgaagatgtc tgggtatcga cttttcactc gatgtgtgtg cgtattttaa
     2101 gaagagatgt tgattttatc gggtataacc ggaactttac aatcatcgat tcttctgaac
     2161 agctgacctt gatgaaacgg atactaaaag aactgaacat tgatccgaaa aaatatgatc
     2221 ctcgaagtat attaggaaca atctctcaag caaaaaacag cctgcagacc cctcaggatt
     2281 ttgcaaaaat gcaaggcagt tattacgaag agattgcggc aaaatgttat gctgcttacc
     2341 aaaaagagct tcaatataat caatgtatgg actttgacga cctgatcatg aatacgattc
     2401 gattatttga agaacatcct gattcactca cgtattatca aaacaaattc cattatattc
     2461 atgtagatga gtaccaagat acaaatcacg cacagtatac gctagtcaat ttattggcag
     2521 gtagatttag gaacctgtgc gtcgtgggag atgcagatca aagtatttac ggctggcgcg
     2581 gtgcagatat gcagaacatc ttggattttg aaaaagatta tccagatgct gcagtaattt
     2641 tgctagaaca aaactatcgc tccacgaaaa acatccttag cgcagcaaac caagtcattg
     2701 aaaacaatag caatcgaaaa ccaaaaaact tgtggacaga aaacaaagaa ggaaacaaga
     2761 tcacttacta ccgtgcagat aatgaacgag acgaaacccg ttttatcgta gaccggatgc
     2821 aagaagagat tcgaagcaat catcggaatt acggcgactt tgccatcttg taccggacga
     2881 acgcacaatc tcgtgtaatg gaagaaactc tgttgaaagc aaatattcct tataaaatgg
     2941 ttggagggca caagttctac gatcgtaaag aaatcaaaga tattttagcg tatttgaatg
     3001 tgctggtaaa tcctcaagat tcaatcagtt ttgagcgtat cgttaattcg cccaaacgag
     3061 gcatcggacc aggatctatc gaaaaactac gcagttttgc ttctcttcat gaatggccac
     3121 tgcttgaagc agcgcaaaat gtggatctgg caaatatcgg tggaaaagca ggacagcaat
     3181 taggtgcatt tggagagatg atccaagaag tcactcagat gatcccatac ttgacagtga
     3241 cagaattgac gaaagaggtt ttggatcgta gcggatatct agaagactta aaaatccaaa
     3301 atacattaga agcacaagca cgcatcgaaa acttggagga atttttaacg gtcacacaag
     3361 aattcgacaa acaattcgaa cagcaaaatg aagaagacgc tgatgcacca gaagaaaaac
     3421 taacggtctt cttaaatgat ctggcacttg tttccgacat tgacaattta gaagaagatg
     3481 cttcccaagt gacattgatg actttgcatg cagccaaagg attagaattt ccagttgtat
     3541 tcctgattgg tctagaagag ggggtttttc ctttatctcg agcattgatg gaagaaagcg
     3601 aactggagga agaacgccgt ctcgcatatg tggggatcac gcgagcagaa gaagcgttgt
     3661 atttaacaaa tgctttctcc agaacattat atggacggac gcaatataac cgaccttctc
     3721 gttttgtaga agaaatcgat caggagttac tggaaatcga aggcatgcgt cctacgccta
     3781 aaaaaacgcc tgtattcgct aaaaaaacag catatagcta taaacagcca gagacagcgg
     3841 ttgttccctc taaaagtgct actggagggg aaaataacag ctggaaacct ggagataaag
     3901 tcaaacacaa aaaatggggt ctaggaacag tcgtccgagt aagcgggacg tcgaaggatc
     3961 tagaactaga tgtggctttc ccaagtcaag gagtaaaacg tcttttggct gcctttgcgc
     4021 caattgaaaa agcttagtag tggagggtaa atgatggaac atgaaatgac gattgacgaa
     4081 gctgctaaac gagcagaaga acttcgtaca agactgaacc aatggtctcg cgaatactac
     4141 gtagaagata aaccaacagt ggaagactat gtttatgata aagaatacgc agaattagta
     4201 gcaatcgagg aacaatatcc tgatttgatc acgtctgatt ctcccactca acgagtaggc
     4261 ggaaaagtat tagaaggttt tgaaaaagtc actcatgata ttccgcttta cagtttgaac
     4321 gacgttttca gcaaagaaga gctgatagct tttgatcaac gtgtacaaaa agcagtggga
     4381 cgtgtagttg actattgctg tgaactaaaa atagatggac tttccgtttc tttgcgttat
     4441 gaagatggaa atttcgtgag aggtgcgact cgcggggatg gaactgtagg agaaaacatc
     4501 actgaaaacc taaaaactgt ccggtcggtc ccaatcaaat taaaagaacc aatgaacatc
     4561 gaagtaagag gcgaatgttt catgccaaaa cggtcatttg tccaattgaa ccaagacaga
     4621 gaagcagagg gaaaagatat ctttgcgaat cctcggaacg ccgcagctgg ttctttgcgt
     4681 cagttagatt ctaaaatcac agcgaaaaga aatctggaca cttttttata cacagtagct
     4741 gatttcggtc ctatgcaagc aaaaacccag tatgatgcgc tagaagagct agaaaaaatt
     4801 ggattccaca cgaatcggga aaaacgtcta tgtcattcga ttgatgaagt gtggtcatac
     4861 attgaagaat atcatgacaa acgtgtggat ttgccctatg aaatcgatgg aatcgtcatc
     4921 aaagtgaatg aattctcgct acaagatcaa cttggtttta ctatcaaagc accgagatgg
     4981 gcagcagctt acaagtttcc gccagaagaa gttgaaacgc taatcgaaaa catcgaatgg
     5041 acagtcggtc gaacaggggt agtaacgcca acagctatca tgacaccagt ccgagtagca
     5101 ggaacgacag taagccgtgc cagcctgcat aacggtgatt atattaagtt gaaggatatc
     5161 cgcttgaaag atacagttct gatttataaa gcgggagaca tcatcccaga agtttcgcaa
     5221 gtcgtgttag ataaacgacc taaagacagc gaagaatacc aattgcctac acattgtcca
     5281 gtttgtggaa gtgaacttgt ccatttggat gaagaagtag ccttacggtg catcaatcct
     5341 aaatgccctg ctcaaatgaa agaaggtttg aaccactttg tttcaagaaa tgcgatgaat
     5401 atcgatgggt tggggccgcg cgtactagaa cagatgtatg ataaaaaact agtagcagat
     5461 gttgctgatc tttacaaatt gacagaagaa gagttattga cgttggacaa aataaaagaa
     5521 aaatcagcaa ataatatttt gacagcaatc gacaacagca aagataattc ggtcgagcgg
     5581 ttgattttcg ggttaggaat ccgacatgtc ggagcgaaag cagcaaaaat tttagcagaa
     5641 catttcggtg atctagaaac attgagtaaa agtgactatg agtcgattat tgcgcttgat
     5701 acgatcggtg atatcattgc cgacagtgta gtcacttatt tcagtaacga agaagtccat
     5761 gaattgatga atgaattaaa acaagcaggc gtcaatttcg aatacaaagg gcttcgaaat
     5821 gcccaattgc aagaagtcga gtctcctttt aaagaaaaaa cagtagtcct tactggtaaa
     5881 ctaacacgat ttactcgtga agaagcaaaa gagacgatcg aaaatcttgg cgggaaagtg
     5941 actggtagcg tatcgaaaaa aacggatatc gtggtagcag gagaagatgc tggcagcaag
     6001 ctgaccaaag cacaagaatt aggaatcgaa gtttggacag aagatcaaat ggcagatgca
     6061 ttggctaaaa gtcgctcagt agaagaatga aaaatgagtt ttttcagaca aatttcaata
     6121 aacaatttca gacacggcac tcttgtgtta aaatagagag caaagttttt aactcgttta
     6181 gaaagaaggg gtagtatggc gattagtgaa gaacaagtga aacacgttgc caaattagca
     6241 aaacttgcgt tcgcagatga agaacttgca agttttaccg accaattagg taaaatcatc
     6301 gatatggttg aaatgctgga agaagtagat acggaaggtg ttccatttac gtcgaatgtg
     6361 gttgaaacag taaacgtgat gcgacaagat cgggcgcaag ctggatggaa ccgcgatgaa
     6421 ttattgaaaa atgtgccgga aacagaagac ggctttatca aagtacccgc aatcatcgat
     6481 aatggggagg ctggcgcata atgacagaat tacacaatcg ttctctagaa gaactgcatc
     6541 atatgcttgt atcgaaagaa atcactgtac aagatttgac aaaaacaaca tttgaacgaa
     6601 tcaaagaaac agagcctgag gtcgaggcat tcattacatt gaacgaagaa aaagcattgg
     6661 aacaggcaaa agctttagat gaaaaaggga ttgatgaaag caacgtcctt gctggtattc
     6721 caattggtat caaggataat atcgtaacaa aagatatctt gacaaccgct gcatctaaga
     6781 tcctttacaa ttttgaacca atttatgatg caacggtcat ggataaaatc tatcaagcag
     6841 atatgatccc tgttggtaag ctaaacatgg atgaatttgc tatgggtgga agtacagaaa
     6901 cttcttattt caagaaaaca aaaaatgctt gggacccaac aaaagtacct ggtggctctt
     6961 ctggtggttc tgcagcagca gttgcagctg gacaaattcc agtttcttta ggtagtgata
     7021 ctgggggaag tatccgccaa ccagcagctt ttaacggcat cgtagggatg aaacctactt
     7081 atggccgtgt ctcacgtttt ggtttgattg cctttgcttc atctcttgac caaatcggac
     7141 caatgacccg tacggtgaaa gataatgcat tagcattgac agctatcagc ggttatgacg
     7201 aaaaagacgg tacttcttca ggcgtttcag ttcctgattt tgcagaggga ctgacaggcg
     7261 acatcaaagg aatgaagatt gctttaccta aagaatactt aggcgaaggt gtggcccctg
     7321 gcgtaaaaga agctgtattg aaagcagcag aaacattccg ttcattaggt gctgttgtgg
     7381 aagaagtcag cttgcctcat tcaaaatacg gtgtggctgt ttattatatc attgcctcat
     7441 cagaagcaag ttccaatttg caacgattcg atggtatccg ctacggttat cgctctgaaa
     7501 atgtgaaatc attagatgat gtatatgtca actcacgttc agaaggattc ggtgaagaag
     7561 taaaacgccg tatcatgtta ggtacattct ccttaagcgc gggttattat gacgcttact
     7621 tcaaaaaagc aggacaagtc cgtacattga tcaaacgaga ttttgaaaaa gtctttgcag
     7681 attatgactt gatcatcggg ccatcttcac caacagttgc attcggaatc ggtgagaaca
     7741 ttaacgatcc aatcacaatg tacatgagtg acatcttaac gatccctgtc aacttggctg
     7801 gacttccagg tatgtctgta ccggcaggtt tatcagaagg attaccagtt ggattgcaga
     7861 tcatcggtaa ttattttgat gaaaaaacga tgtatcaagc ggcatatgcg tttgaacaag
     7921 caacagaatt ccataaacaa caaccagcta ttttaggagg gaaagacgaa tgaattttga
     7981 aacagtcatt ggactagaag tccacgtcga gttaaaaacc aactcaaaaa ttttctctcc
     8041 agcgccagct cattttggtg cagaaccaaa cagcaataca aacgtgatcg actggggtta
     8101 tccaggcgtg ctgccagtaa tgaataaagc tgcgctggaa ttcgggatga aagcagcttt
     8161 ggcattaaac tgtgaaatct ctaaagatac tcattttgac cggaaaaatt acttttaccc
     8221 agataatcca aaagcatatc aaatttccca atttgatcaa ccaatcggtc atgacggatg
     8281 gatcgaaatc gaagtagaag gtaaaaagaa aaaaatccgg atcgaacgtg tccatttaga
     8341 agaagatgct ggaaaaaaca tgcatggtat tggcggttat tcttacgttg atttgaaccg
     8401 acaaggcacg cctttgatcg aaatcgtttc tgaagctgat atgcgttcac cagaagaagc
     8461 atacgcttat ctagaagcat tgcgatcaat tatccaattt acagaagtca gcgatgtgaa
     8521 aatggaagaa ggctctatgc gctgtgatgc caatatttct cttcgccctt atggacaaga
     8581 agagttcggt acgaaagcag aattgaaaaa cttgaactct ttatctttcg tgaaaaaagg
     8641 tttagctttt gaagaaaaac gtcaagcaaa agttcttctt tcaggaggag aaatccaaca
     8701 agaaacacgc cgttttgacg aaacaacgaa taaaacagtt ttgatgcgtg tcaaagaagg
     8761 gtctagtgat tatcgttact tcccagagcc tgatatcccg aaattcgtga tcgatgacga
     8821 atggattcaa aaagtaaaag ctagtttgcc tgagatgcca gcttctcgtc gcgaacgcta
     8881 tatccgtgag tttggacttc cagagtatga cgcaatggta ttgacactta caaaagaaat
     8941 gtctgatttt tttgaagctg ttttggaaaa tggtgcagat gccaagcaag catctaactg
     9001 gttgatgggt gaagtttctg cttacttgaa cagtgagaaa ctggaattag ctgagacaaa
     9061 attgacacct gagaacttag caggaatgat tcgtttgatc gccgatggaa cgatcagctc
     9121 aaaaatcgcc aaaaaagtct tccgtgaatt gatcacaaat ggcggagaag cccaagaagt
     9181 agttgaaaaa aatggttggg tgcaattatc tgatccgaac aaactactgc caatcattaa
     9241 tgaaattttg gataacaacc aacaatctgt cgatgatttc aaaaatggaa aagatcgtgc
     9301 ggttggcttc ctagtcggtc aaatcatgaa agcaactaaa ggacaagcaa atcctggtgt
     9361 cgtgaataag ctacttaaag atgaattagc gaaacgatag aggctgaaaa tgaaaaaagc
     9421 acgcgtaatt tataacccca cctcgggaaa agaattattg aaaaaaaatt tggcggatat
     9481 cctacaggca ttagaagaag caggatttga agccagcgcc tatgcaacta caccagaacc
     9541 agattcagcc aagaatgaag catgtagagt cgcagaacta ggttttgatc tagtagtggc
     9601 agctggtggc gatggcacaa tcaacgaagt ggttaatgga atcgctccgc ttgaacaccg
     9661 tcctaaaatg gccatcatcc cagctggtac aacgaacgac tatgctcgag cattaaaaat
     9721 tcctagagat aatattaaag cagcagcaga agtgataaaa aaacaccaaa ccgtaaaaat
     9781 ggacatcggc ctttctgata acagttactt catcaatatc gctgcaggtg gctatttgac
     9841 agaattgact tatgaagttc catcagaact aaagagtatt tttggttatc ttgcttatct
     9901 tgcgaaagga gcagagatgc tccctcgagt aaagccaatc aaaatgcgct tgaagtatga
     9961 tgaaggggaa tatatcggaa atgcttcgat gtttttccta gggctgacga actctgttgg
    10021 aggattcgaa cagatcgcgc cagatgccaa attggatgat gggaagtttt ctttaatcat
    10081 tgtgaagaca gcaaatatct ttgagatctt gcatattgca gcactcatgc tgaatggcgg
    10141 tcgacatgtc gatgatccaa gaataatcta taccaaaaca agcagtttgt tcgttgaaac
    10201 agaagatgat atcaatcgac cagtaatgat caacttagat ggtgaatacg gcggggaagc
    10261 accgatgcat ttccaaaatc ttcatcaaca cattgagttc tttgccaata ccgatcagat
    10321 tcctgatgaa gcaatcacag gtacagatga agaagaatta gaggttgtca gcaaagaatt
    10381 cgtaaaagaa gtcgaacgtt taacggatga agatatcgac ggtgacggaa aaatagcaga
    10441 cgaaacacct aatcaaaaga attaatcaaa agccggtgct gaacgtagta aggtcagtgc
    10501 cggttttagt tgtgtaatta gctgatttat agtagagttc agtaggattg aaaaataggc
    10561 ttaaaggagc aaaatatgac agaacagcaa atagtaaaga aaaacgaacg atatacagtc
    10621 gaaatcgtcg acttgagtta tgaaggaatg ggggtagcaa aaatcgatgg ttatccatta
    10681 tttatcgaaa atgcactccc tggagaagaa gtagaaatac tagtagtaaa agcaggcaat
    10741 aagtttggat atggaaaagt cgaaacattt attacacaat cacctgatcg tcagcctgta
    10801 gaaaacaatg cattacttcg cataggtatc gcacctttag cccatttgaa gtatgaacaa
    10861 cagcttgtct tcaaacaaaa acaagtagag catgtaatgg cgaagattgc taagatgcca
    10921 gaagttcctg tacttccaac ggtcggaatg gcagaaccat tcggctaccg taataaagca
    10981 cagatccctg ttcgccgtat cgatggacag ttagccaccg gtttttacaa aaagaatagc
    11041 catgatctag tccctatcga agatttttat atccaagatc ctgtcatcga tcaagcaatc
    11101 aaagtagtca gagatatctt gcaacggttc caagtacgag gatataatga agaaaaaaat
    11161 gaaggacagc ttcgtcacat cattatccgt cgtggtcatt attcccatga aatgatggtc
    11221 gttttagtta ctcgtaaaga aaaattcttt aaatccaagg aaattgctga agctattcat
    11281 gaagaattgc cagaagtggt ttcggtcatc caaaatatca atgaagaaaa aacaaatgtg
    11341 attttaggag acaaagaaaa agttttatat ggcagagact atatcgaaga tcagctatta
    11401 ggaaaaacct atcgaatctc agcaaagtca ttttatcaag taaatactca acaagcagag
    11461 tatctgtacc aaacagccat cgagtttgcc gagttagata aaaaagacat tgtgatcgac
    11521 gcttattcag gaataggtac gattggcttg tctttagcag acagagtgga taaggtgtat
    11581 gggatggaag ttattccaga agcaattgaa gatgcacagt tcaatgcttt aaataataaa
    11641 atcgaaaatg ttcattatga agtcggaaaa gcagaaaaag ttatgaaaaa atggcaagaa
    11701 aaagggatca aaccatctgt gatcgtagtt gaccctccac gaaaaggatt agatcatcat
    11761 tttattgaat cagcaatcga aatgtcacca gaacgaatcg tctatatctc atgtaatccg
    11821 gcaacttttg caagagatgc taagttattt gcagaagcag gttatgccgt gaagaaagtt
    11881 cagcctgtag atcttttccc gcaaacccat catatcgaat tagtcgcttc attcgttaaa
    11941 ggagaataaa aatggaccaa aaagaaaaaa tgaaagaatt gatcaaaaag aaacaaggtg
    12001 gaggccgatc caaacaaatg gaaacaccta agaatgatcg taaaaacatg agaaaaggcc
    12061 ctaaaatctt taataaatag acgtgctaaa gaaagactaa gaagtgttaa cttttgttat
    12121 tgtttcttag tctttttagt tagtctacat tattttggcg atttgccaat aaggactgtt
    12181 gagttgtgca aaatcaaatc tgggtcagaa tgaacgtcat tctgtctcag atttttcgtt
    12241 atttcaattt gattaactga ttgatcaaaa agatttttat tttcatattc tcaaatgatt
    12301 caacactaaa tatacatgtt tgacgcggaa attattattc gattttggcg gcatcagggg
    12361 ggatgacgac gtagcagacc cattatttta ctcaagaaaa tgtccgtgcc tattatttag
    12421 aatacgatag tgaacgtgct gggagttttg ttcttttaga gaaagtctct gaagataaat
    12481 tagttgtctt agattttgac tgtaacgaaa aatggcgaaa tggaagagca ccagcaagtg
    12541 attgaccgga tctacgaagc gacacgatat ctgcctttgg atcgtttgtg cttaagtcct
    12601 caatgtggat ttgcttcaac agaagaagaa aatgttttgt ttgaagaaca atggaaaaaa
    12661 tttcttttgt caaaagcatt gcagaagaag tttggggaaa atcattaaat catctaggag
    12721 agcttgatag gaaataacac tatggtataa tcagaatgct taatactaac tactgaggga
    12781 gccttatgaa aaagaaaatt cttaaattta tcggatggtt cttcggaatc attcttggga
    12841 tcgcgtttgc aatctttctt gccttccagc tttcccccag acctggagca ttcttgatca
    12901 accatatgtt ttcaaatact gttcaaatca ctgataaaaa aacgttcgat caagcagaaa
    12961 aaaacgtggc gaaaaaaaca gatttgacgt atgagtccaa gtataaagag aatacttatg
    13021 acatctacta tccaaaaaac agcaaggggc ctgttcctgt tctattttgg gtacatggtg
    13081 gaggattcgt cggcggagat aaatcgggtg tcaaagaatt tgcgacaaaa ttagtttcag
    13141 acgccaacat cgcagtggtt gcgatgaatt atgaattagc gcctgattca gaatacccta
    13201 atcaagttct tcaagtgaat gaactgatca aagatttatt agctgaagaa aaagacgaca
    13261 aattgctaga catggaacaa ttattttttg gtggagatag tgcaggttca caaatcgcat
    13321 tgcaatatgc agctatacaa acgaatgatg cgtatgctaa acaaatgaaa atcaaacagc
    13381 tacttccaaa agatagtctg aaaggaacca tttcttattg cggacctgtt gatttgaagc
    13441 taacagcaca gcagcattcg gatgatcgat ttatgaagtt tttcgtcaaa accgttgcgt
    13501 ggtcgttgat tggaacaaaa gattggaaaa cgagtgagca attgaaagaa gctagtgtgg
    13561 ctgaccatgt ttctaaggaa tttccgccaa cgtatataac tgacggaaat gcatactcat
    13621 tccaggagca aggtcaagca ttagaaaatc ggttgacaga attaaaggta cccgtgcaat
    13681 ccttgtttta tacagataca aaaaaagaga ttacccatga ataccaattt gattacacgc
    13741 taaaagaatc gcaaaattgt taccagcaga cattggattt tgtgaataag tataagtaag
    13801 aggttgtgaa aaagccgttt cgttttgagt atgaagaaac gaagcggctt ttcacaacct
    13861 ctctttcaat acctttttgt tcttgggata aaactttccc taacaatcaa tcgtgcagga
    13921 taagtcaaaa tgattggttc gtcccgtata ccgtcaattc gctccaatgc cattcgaaca
    13981 gctgcttgcc caattgattt cgcattgatt tgaacactgg tcaagccagg ggagaggttt
    14041 gcgattgtct cgatattatc aaagcttgct acaacaatct cttctccaat ttggatattt
    14101 ttttgtttca atgcccgata gacaccaatt gccattggat cgctcccgac aagaatggca
    14161 gtaggaagag gggattcatt ttctaataga ttagtcgcaa gtacctcacc ttgtttttct
    14221 gtccagccac ctagatgata agacatatat ttttctaagt gatgatcgat cataaaatgc
    14281 tgataggcac gcatcctctt ttcatttata gaaatctgct tcccaccgaa ttcatccata
    14341 tcgactttat atcccccgat ataggctatt cttttatgac cattttctaa gaacaattcc
    14401 agtacggttt tagtcatccg ttcaagatct gcatacacca tatcgacctc ttgctggatg
    14461 tcagggttat ccacgacgac tatttgcatg ttttgtttta acaaggcggt aatcgattct
    14521 ttcgtaacag tcccaacaac gatcaccgca cctaactgat ctagatcttc ccattgttta
    14581 ggattatcag atagattata gattcgattc atccctaaat gcagacgtcg agcttcttct
    14641 tccatcccta ctcgcaaatg tttgtaatag atatcctgtt cttcgctcgc tttgccgatc
    14701 gtagagatca caccaatcga aggcattctc tttttgatat atttacgagt actgatgtca
    14761 taatccaacg cagcagctgc ctctactatc cgttgccgag tagtctgagc cacatggatc
    14821 gtctgatcgt tattcaacac acgggaaact gtagcaggag agacatttgc ctttcgtgcg
    14881 acatctctaa ttccaaccat ttttacacac tcctcaaaaa aataaaaaat ttttattgac
    14941 aaaattgttt agtaaacagt atacaggaat tataaaaaaa agtaaacggt ttccgttttg
    15001 ttgggagtga aatgatggat attacgcata gaaaaacaga taaaaatttc atcttatttg
    15061 atgaaaagag ccgagtcttc catttacgaa atacatttct ttcttatctg ataaagatag
    15121 aagaaagcaa tgtattggcg catatttatt ttggcaaacc agtcaagcag tacaaagaca
    15181 ataaaaatta tccccgaaga gatcgtggat tttcaggaaa tgttccctta aatcctgacc
    15241 ggtctctgtc gaaagataca ctaccgcaag aatactcttc tcatggcagc atggactttc
    15301 gaacgcccgc atcgatcatt cagcgcaaga atggatcaga cttactggat ctgagatatg
    15361 acagccatta tattacagat gggaagccag agatcgaagg cttgcctcaa acttatgtga
    15421 tggacaagtc agaggcacaa acgttggtga tttcacttaa ggatagagaa acagcgattt
    15481 atttcgattt gttctatacc atatttactg atagagcagt gatcacacga tctgtaaaga
    15541 taagaaatga aaccggagaa acaatcaaac tagaaaaagc ggctagtttc cagctagact
    15601 ttgcccatac taggcgattt gatgaagtca ttgctttgcc aggagcacat gtcaatgaaa
    15661 gacagatttc acggcaatct gttttatctg gaacaaaagt atttgaaagc cgtcgaggaa
    15721 cgagcagtca ccatatgaat aactttattg ctttagttca tcatcatacg acagaaaata
    15781 ctggagaagc gatcggactt caatttgttt attccggcaa ccattctttc gaacttgaaa
    15841 aagatcagat caatcaattg agagtcgtcg gtgggatcaa cagccatcgt ttttcgtggg
    15901 aattgaatgc aggccagtct tttcaaacac ctgaaatgat cctttcttac tcaagtcagg
    15961 gattgaacaa aatgagtcag atccaccatg agttgctacg tgaaagaatc gcaagaggtc
    16021 gtcatcaatt tgctgaacgg ccgattctgg tcaataactg ggaagccact tactttgact
    16081 tcaatagtga aaaaatcaag gcgatcattg atgaagcaaa ggagctaggc atcgaaatgt
    16141 tcgtattaga tgatggctgg tttggaaaaa gagatgcgga caattcttca ttaggagact
    16201 ggttcgagta tgaaggcaag ttgacaaatg gattacgtga aatagcagat tatgctcata
    16261 gcaaaggatt gaaatttggt ttatggtttg aacctgaaat gatctcggtt gattctgaac
    16321 tgtatcgaac acatcctgat tttcttatgc aggagccagg tagaatgcct tctgcttcca
    16381 gatcacaaca tgtactggat tttacaaggt tagatgttcg gcagacgatt gagaaacaaa
    16441 tgagaaagat tttagatacg attcctcttg actacatcaa atgggatatg aaccgttcgc
    16501 tttcagatgt ctattcgatt acccttgacc cacagagaca aggagaagta gcgcatcgtt
    16561 atatgctcgg gctttatgaa ctacttgaac atttgacaac tgattatccg gaaatcttat
    16621 gggaaggctg ttctggtgga ggtggacggt ttgatgccgg gtttatttat tatatgccgc
    16681 agtcatggac aagtgataac acggatgcag tggagcgtat gaaaatccaa tatggaacaa
    16741 gccttgctta tccgatttcg tccatcacag ctcatgtatc agctgtacca aatcatcaga
    16801 ccgacagatc tacttcgttg aaaacaagag gagaaacagc tatgagcgct gtttttggtt
    16861 atgaactgga tttgacaaag ctgtctcctg aagaaaaaaa gcaagtaaaa gaccaaatta
    16921 tatcctatca aacgattcgt ccggtgatcc agtatggcca ttattatcgt ttggcgagtc
    16981 cttttgaaga aaatattgcc gcatggatgt ttgtgtctcc taaacaagat gaagctattg
    17041 tgtttttagg gaggatacta gcttcagctc aaccagcgtt ccatgaagta tatctgatgg
    17101 ggttagatga tgaggcactt tatcaggaac agacctcgaa gcggatattt tcgggggccg
    17161 aattgatgac agttggactt tacttccccg attttcaagg tgatttccaa acagaactgc
    17221 ttcatttcaa aaagttatga gagagaagga aaaaagtatg aaagcaaata taaaatggtt
    17281 agatgatcca caagttttta gagtgaacca atcaaatgca catagcgatc atgtttgtta
    17341 tgcaacaagg gaagaagtag aaaccacatc ctcccttaaa cagtctttaa atggatcatg
    17401 gcgtttttgt tattcgccaa atccttcggt acgaccaaaa acattttata aaaaagattt
    17461 tgatgcctgt tcttttgatg aaatcactgt tcctagtcat attgaattag caaattatga
    17521 caagatccat tacatcaata cgatgtatcc gtgggaggga catgtatttc gccgtccccc
    17581 tttcacgaca agccctgaga aagaggcgga agggatcttt tcagctgcta aagacaatcc
    17641 ggttggttcg tatttgacga cttttcgatt agaagaaggt ctaaagggaa aacaaatctc
    17701 gattcatttt gctggtgtag aacaagcaat gtttatttgg ttgaatggtc attttatcgg
    17761 gtatgccgaa gattcgttca ctccgtctga atttgattta acaccttatt tggaagaaga
    17821 aaatattcta gctgtggagg tttacaaaag aagtacagct gcattcttgg aagatcagga
    17881 ctttttccga ttttttggga tcttcagaga tgtcttctta gttgctcgag gacaaaacca
    17941 tttagaagat ctttggatca aacctcgctt agatgacaaa tgtcaaaatg gcaaacttga
    18001 agtagatttg tcttttgagc aagtagccaa aaacagtcag ctgaatgtag cgatactaga
    18061 tcctgatggg aaggaaatct atcaacagca atatccgtta aaagagcaaa tgacgattcg
    18121 catcgatgga tttgaaaatg tggcactgtg ggggcatttt cagcccaatt tatataagct
    18181 tgaattggag acgatagacg aagaaaaaag agtaacggag tatattgact attccttcgg
    18241 ttttcgtaaa atcgaaatca aagataaaat catctacttc aatggaaaac ggatgattat
    18301 caacggggta aatcgacatg agtggcatcc gaaaaaagga cgcgccatca ctatagaaga
    18361 tatggaaaaa gatttggcta tcataaaaaa tgcaaagatc aacggcgtac ggacatctca
    18421 ttaccccaac cagatcactt ggtattattt atgcgaccaa gcaggaatcc atgtgatggc
    18481 ggaaacgaac ctcgaatccc atggctcatg gcaaaaaatg ggcgcatttg agccttctta
    18541 caacgtacca ggtgcagtac ctcagtggca ggcggctgtt cttgatcgag caaaaacgaa
    18601 tttcgaaaca ttaaaaaacc atccaagtat tcttttttgg tctcttggaa atgaatctta
    18661 tgcggaagaa aacattcgac aaatgaacga ttacttcaaa aaagtagacc ccgatcgact
    18721 tgtccattat gaagggaatt ttccaaatcc agcattcgaa gattcgattt cagatgtaaa
    18781 aagctgcatg tatgcgccac cagaagagat cattgactac cttgaaaata aagcggaaaa
    18841 accgttcatc ttatgtgaat atatgcatga catggggaat tcgttaggtg gaatggattc
    18901 ttacatgacg ttgcttgatc gttatgaaat gtaccaagga ggctatatat gggattttaa
    18961 agatcaggcg atccaagtga ctgatccaat cacaggcaga gaagtgatgc gctatggcgg
    19021 tgactttgac gataaaccaa gtgactatga attctcaggg aatgggatcg tttttgcaga
    19081 tggacaagaa aaacccgcca tgcaggaggt aagatattat tatgaaaaat acagtaaata
    19141 aaagtcatat ggatacggaa aaagttgcaa tcgtcttcgg cgactgtaca ttaggtgtca
    19201 aatcggggaa tacgcattat attttttctt atacaagagg cggactggaa tcgctcaata
    19261 aaaacggaaa agaatggcta taccgggaaa cacttccagt tttttggcga gcaacgaccg
    19321 ataatgacag aggtagcgga tttggattta aatccggtat gtggttagga gccggattgt
    19381 atccaaaagt caaagaaata gaagtactgg tggacaataa aaagatcgat ttgccgattg
    19441 ctccagtaaa taatcaatat tcaagtaatg aatacgctga aacggttgaa atcattttta
    19501 cactggaaat caacacagta ccaaaaaccc aagtgacaat ttcctaccaa atcgctggag
    19561 agggtaaaat gcttgtcaat atgcattatt atggacaaaa aggattaccg gaattacccg
    19621 cattgggttt aaggttcatt atgccaacga aagcaaaatt ttttgagtat gaaggcctat
    19681 caagggaaac atatccggat cggatggctg gtggtgtcga aggtatttat aaagtggcag
    19741 gactccccgt ttccccatac cttgttcccc aagaatgcgg catgcatatg gaaacgaaat
    19801 gggtagaact aacaagaaat caaacgttgg ataatacgga taaagatcaa gaagattttt
    19861 cgttgcgatt tgaacagcag gatacgccat ttgctttttc cgctttacca ttcaaagcag
    19921 aagaactgga acaggcaaca catatagaag aactaccgcc agaaagacga acggttctta
    19981 cgatttttgc aaaagtaaga ggagtcgggg gtatcaatag ctggggagcg gatgttgagt
    20041 caccttaccg aatcagcagc gaagaggacc atgaaatcgg ctttattatt cagtagcaat
    20101 ctttagatta ttatttgaaa aacggagttt acaagacaaa gctgctttat tctatatgtc
    20161 atgaacaaga gagtaaaaaa gttctcagat acttttgttc atgactattt tcttcaataa
    20221 aaccaattgt tatttttctg aaaaacaaag ttaactatca gaaaattaaa aaaagtttca
    20281 taaaaatgat tgacagtcga tttttttatg tctatactag gtacaattct tacatcagtt
    20341 tggagcgatt ttttatgaaa tctagaaaac ttacaaaact gaatacgtat tactttagct
    20401 attttagata ggtttgtatt catgacttcg tgggtacaaa caaaccaggt ttgtatctat
    20461 gatggctaaa gatttttaaa cacgacttac agccacgtag agaaattcat ctatagtggc
    20521 tattttatat ttttgcagcg ctttttaagg ctcgttgaag atgttcactg tagaggcaat
    20581 ttcctacagg gacatctttt tttgttgatt atctgggtca taagtaggaa agaaggagcg
    20641 aaaatgagaa caacaggaca cggtcattta gtaggaatta atgtaaaacc accttgaaaa
    20701 agtagagaaa atcagccaag atagataagt aaacaaaaga aagcgggaaa aacaatgata
    20761 gtaattatga aaaaagaagc aacggaagaa caaataaaaa aagtcgtcga tcatatcgaa
    20821 aaagaaggat tcaaagtctc aatcgatcaa ggaacagaac gagtagtgat tggactaaaa
    20881 ggtgatacgc gaagtttaca agaaggagca tttacacgct atgaaggagt agaaaatgct
    20941 gtgcgtattt taaacacata caaattgact tctcgagaat tccatcctgg caatacagtc
    21001 gtggatgtag acggagtaaa aattggtgac ggcagtttcg tgacgatggc tggtccttgt
    21061 tctatcgaag gattagacca aatcagagaa tgtgcgcgaa tggccaaagc cgggggcgca
    21121 aaaattctgc gaggtggtgc cttcaaacca cgtacttctc catatgcttt ccaaggttta
    21181 gaagaagaag gattgaaata catccgtcaa gcggctgatg aatttggaat gaaagtgatt
    21241 actgaagtga tggatgaagg gcatatcgat atggtggctg agtacagcga tatcctacag
    21301 attggcgcac gtaatatgca aaattttaaa ctgctatctg ctgtcggtaa aacaggtaaa
    21361 cctgttggat tgaaacgtgg aatttccggt acgatcaatg aatggcttaa tgctgcagaa
    21421 tacattgcag tcgaagacaa atctcctgtc atttttatcg aacgtgggat tcggacttac
    21481 gaaacagcga cacgtaatac gtttgattta agtgctgtcc cattgatgaa aaaattaact
    21541 catttccctg tgattgttga tccaagtcat ggtacaggaa tttgggaact tgtaccacca
    21601 atggctcgtg cgggtgtggc aagcggagca gatggcatga tcgtagagat ccatcctgat
    21661 cctgcaaatg cttggtcaga cggtccccaa tcgttgaatg aaaagactta ctcacgcatg
    21721 atgaaagaag ttgcgatcat gaaagaagca atggaaaaga ttcagacact cgattaattc
    21781 cagcttttta aaagaaagaa gtgaaacgaa tgcttactgt acatgttgat aaccaaaaat
    21841 acgatattca tattgaaaaa ggcgcactag aacaggctgg atcatggctt caaacgattt
    21901 ggagacctca aaaagtagct gtgatcactg atacaaacgt tgctccacta tatgcagaaa
    21961 aaatcatgtt ccaattgaga caagctaatt ttgaaccagt cctttcaatc gtaccggcgg
    22021 gtgagaccag taaatcttta gaacaagcag ctgagttata cgatttttta gcagataatg
    22081 attttacccg cagcgatggg atacttgcac ttggtggagg aatggtgggt gatctagcag
    22141 cattcgtggc ctcgacgttc atgcgtggga tccatttcgt tcaaattccg actacgctac
    22201 ttgcacaagt agattctagt attggcggga agacagcagt caatacaaac aaagcgaaaa
    22261 accttgtcgg aacatttagc cagccagctg gtgtattgat tgatcctgag gttctaaaaa
    22321 ctttgccggt acgtcgttta cgagaaggaa tcgctgaaat catcaaatca gcagctatag
    22381 cagatgcaac gctttggaaa cagctgaacg agctgaaaga cgaaaaagat cttctggaac
    22441 atgctgttcc aatcattact gctacgttgg aaatcaaacg aaaagtagtg gaagaagatg
    22501 tctttgacca aggaaatcga cttattttaa attttggtca tacaattggc catgcaattg
    22561 aaaatacagc aggatatggg gtagtcagtc atggagaagg agtagctatt ggaatggtag
    22621 ccatcacttc tcatgcagaa aaaatcggct tgtctccaac tggatcgaca gctgctttag
    22681 aaaggatact tcaaaaattc catctgccga ttacgtacga tctaagtcat ccagatgaat
    22741 tattccacgc gataacccat gataagaaag caagaggaag ccaattgaat atcatcttgc
    22801 tagaaaagat tgggcaagca aaaatcgttc ctgttcccac agagacattc aaagattact
    22861 taggaggact gtaagatgcg ttatatgact gcgggagaat cccatggacc agaattaaca
    22921 gccattattg aaggactacc agcaggatta cctctgtcag aagaagaaat caatcacgaa
    22981 ctcgctcgca gacaagctgg ttacggcaga ggaggaagga tgaagatcga aaaagatcgt
    23041 gttcggatca cgtctggcat ccgtcacggc aaaacaattg gttcacctgt cactttagtg
    23101 gtagaaaata aagattggaa aaattggaca actgtcatgt ctgtagcaga agtgcctgaa
    23161 aaagaccaat cactgcggcg agttgcacgt ccgcgtccag gacacgcgga tttggtaggc
    23221 ggtatgaaat accatcatcg agatcttcgg aatgtgcttg aacggtcctc tgcaagagag
    23281 acgaccatgc gtgtagcaat cggcgcaatt gccaagaaaa ttctggaaga acttgacatc
    23341 atcgtagcag gacacgtgat ttgtcttggt ggaatccaag cagaaatacc tggaaatatc
    23401 tcgattcaag aaatcaaaga aatttctgaa gcgtcagaag tacgagttgt tgatccagca
    23461 gttgagcaaa gaataaaaga tttgatcgat cagacaaaga aaaatggaga tacgatcgga
    23521 ggaattgtag aagtgctcgt tggaggcgtt ccagctggat taggaagcta cgtacaatgg
    23581 gacacgaagc tagatgccaa aatcgcacaa gctgtggtta gtatcaatgc ctttaaaggc
    23641 gtagaatttg gggtcggatt cacttctggt tcattaccag gctcagaagt gatggatgag
    23701 atcctatggg aagaagaaag aggctatttc cgacgtacca ataatctagg cggcttcgaa
    23761 ggcggaatga ccaatggcga accacttgtc attcgcgggg tcatgaaacc cattcctaca
    23821 ttgtacaagc cacttcaaag tgttgatatc gatacaaaag aaccttacaa agcaagtgta
    23881 gaacgttcgg atagtacagc agttcctgca gctagcgtcg ttgcggaaaa tgttgtagcc
    23941 actgtggtag cgacagagct attgtcaaaa ttcccaagtg attcgcttgt tgagttgaaa
    24001 gctgcagtga aggagtaccg tgactacttg aaacattact aaaaaggggg caaataagat
    24061 ggcacaacat gtttttatcg tggggcttgg actgattggt gcttctatgg cactttgtat
    24121 tcgtcagacc aatccagaac tgatagtagt tggttgggat agtcagtcaa aaacccgtga
    24181 gcaagcagta gaacagcaga tcgttgatta cgttgcaagt gattttgaaa caggtgcaga
    24241 acaagcagac gttatcttat tagccgttcc cgtccgtaca accttagctt atcttgatgt
    24301 ccttgaaaga atcaacttgt ctgatcacgt catcattacg gatgtcagca gtacgaagca
    24361 gcaagtcgtg acatccgctg agcagaaaaa tcttcggttt gtcggtggac atccaatggc
    24421 tggttctcat aaatcaggta tacaggcagc agatgctaaa ctatttgaaa atgcctatta
    24481 catctttaca cctttggaaa agacgaaaaa agatgttgaa aaactgcaag aactattttg
    24541 cggaaccaaa gcaaaatatg taactcttac agcaagagaa catgaccgta taacaggaat
    24601 gctaagtcat tttccacata ttctggcagc tggcttagtc aatcaggcag aacaattcaa
    24661 tcaagagtat ccgcgagcca aacaactggc agcaggaggc tttcgagata tcactaggat
    24721 cgcttcctca gatcctgtca tgtggacaga tattttgttg agcaataagc agatattatt
    24781 ggaacgattg gcagattggc aacaagaaat gacacaaata gcagaatgga tcatgactga
    24841 gaaccaatcg gaaatctttt cttttttcaa tcgggcaaaa gaaagtcgag accagttgcc
    24901 tgtccataag caaggcgcga ttcctgcctt ttttgattta tttatcgatg tgccagatga
    24961 acctggcgtt attgcagaag taactggact gatcggaaaa gcgggagttt ctttgattaa
    25021 tttgaagatc caagagacca gggaagatat tttaggaata ctgcaaatca gttttaaaaa
    25081 ccaacaggat ttgttacaag caaaaagaat cattatgtct aataccagtt atcattgctg
    25141 gatcaaatag gaggctggat aaatgcaatt attacaacaa atacatggat taagagggac
    25201 tgttaggata ccagcagata aatcaatttc ccatcgcagc atcatgtttg gagcaattgc
    25261 tgaaggaacg acgactatac aaaatttttt gcgcgcagaa gattgtctga gtactttaca
    25321 tgccttccaa caattaggtg tcgagatcga agaagaggaa gaggtgatca agattcatgg
    25381 tcgcggtagc cactcatttg tccaaccaac cgaatcaatt gacatgggaa actccggtac
    25441 gaccatacgt ttattgatgg gtattttggc tggacagcct tttacgacta ctctgttcgg
    25501 ggatgcttcg ttgtctaaac gtccaatggg gcgagtgatg gaacctttac gcgagatggg
    25561 cgctgacttg caaggagaag aaaatgacca gtatctacca atcactgtga caggaacccg
    25621 ctctttatca cctatccgat acaatatgcc tgtagccagt gcgcaagtca aatctgcttt
    25681 gctgtttgcg gcattacaag cagaaggcac atccgtaatc gttgaaaaag aacgttcccg
    25741 taaccatacg gaagaaatga ttcgtcaatt tggcggaagg atcacagtgg aagataaaac
    25801 gatcatagtg accggaccgc aaaaattaac tggtcaacag ataactgttc caggtgatat
    25861 ttcatcagct gctttctttc tagcagcagg acttcttgtt ccggaaagcc aactgttgtt
    25921 aaaaaatgtc ggggtcaatc caacaagaac tggtatctta gatgtgttgg aggagatggg
    25981 cgcagcgatt acccagacga atcacaatga acagaaccaa tcggctgatt taagtgtcaa
    26041 gacgagtcat ttgaagaaag caacgattgg tggagaaatc attccgcgtc tgattgatga
    26101 attgcccatt ctagctttag tggctactca agcagaagga atcacgatca tcaaagacgc
    26161 agaagaatta aaagtaaaag aaaccaacag aattgatgcg gtggcagaag aattacagaa
    26221 aatgggagca aagataaaag cgacagcaga cggtctgatc atccatgggc cgacacctct
    26281 gcatggcgca aaagtgtcca gcagaggcga tcatcgaatc ggtatgatgc tgcaagtagc
    26341 tgctttgata gctgatggac cttgcgaact agaaggagct gaagctgttt caatctctta
    26401 tccggcattt tttgacgatt tagcagaact tgtgtcagga ggagaagctc atggctagca
    26461 ttttgctgat tggtttcatg ggcgctggaa aaacaacaat cggtaaaggg ttagctcaat
    26521 gtttacaaaa agagtatgta gatttagata caaagattga ggaacatatc caattgtcga
    26581 ttgccgaata ttttcactat tacggtgaaa aaagctttcg aaaagtggag tcagatattt
    26641 taagaaagct gtcaaatgaa gacaaaatta tcgcgactgg tggagggatt gtccaaagtg
    26701 cagaaaatcg gcgtttttta aaaacacagc cgattgttct ttacttagag gcagaagcgg
    26761 actgtctagt tgatcgtatc caacaagatg aaacgtctat tcgaccttta gctcttggaa
    26821 aaacaagaga agaaataaaa gcattattgg cacaacgact ttcttggtat gaagaaagtg
    26881 cgacacatcg aatcaacacg accaatcaaa caccagaaaa gatcatcgat accattatag
    26941 aaaggatcaa aagcatatga acgtcagcta tctagggcca gaaagttcat tcacttatca
    27001 ggcggcttgt cagctatttc ctacagaaca attgactgcg tatgcttcca tccctgtttg
    27061 tttgcgcgct ttgtttcgca aacaagtcga tctggctgtc gttcctgtag agaattcatt
    27121 ggaaggagct gttcatcaca caatcgatct tctttccaaa catccagaag tcgaagttaa
    27181 aagtgaaatc gttcttccta tcaagcagca gcttttaggc aatccagcaa caaagattac
    27241 aaaaatcctt tcacatccac aagcactagc acaatcacaa cagtttttag aaacgcatta
    27301 tcctaatgtt cctttagtag caacagaatc aacaactgct gcagcaatgt atgtagcaga
    27361 acatccgaaa gaagacgcag cagcgattgc ttcattagaa acagcacagc atgttggatt
    27421 ggagatctta gctgagaata tccaagataa tgagttgaac cagacacgtt tttggatcgt
    27481 cggtgaccga aagatgacca gccagcagtc agctccagta aaaatgagtg tcatcttgac
    27541 actacctgct aatcggccag ggatgcttca taaaatgctg gcagcttttg gctggcggga
    27601 aatcaactta agtaagattg aatcccgacc attgaaaact agcttgggag aatatttttt
    27661 cgtgatcgat ttgttgttgg accgtccaat gacattagta gagaatgcgc tccaagaaat
    27721 caagatgctc ggaggagaaa gtcaaatatt gggctgttat ccagtgctga cagtagaaga
    27781 gacgcgtaga tgaaagtcaa gaatactgat tgatttattt aacttaaaat aaaaaaatca
    27841 gcgcttggct attctttatt tttgatattc tgattgattt ttaggaagaa gcggtagaca
    27901 aatcgttaca gtcgttcctg tcccaatcac tgattggatc gttaagccat atgcatcgcc
    27961 atacattagg cgtatccgct catctacatg gctgatgccg attcctgaaa aatgatcatt
    28021 tttttgtttg gtattttcag tatcgaagcc atcgccgtta tcaatcactt cgaataaaag
    28081 aagctgattt tttgttttgc cgtacaccgt gatgaatcct tgcgttttat tgtgaaaagc
    28141 atgaagatag gcgttttcga taattggttg aaggatcata ttcggcatag ataatgactg
    28201 cagttcatca ggaatcatta ttttagccga gattctttcg ccatatcgca tactcaaaag
    28261 atcgatgtaa ctttgtacgc ttttgatttc ttccttgact ggaatcactt cttctttttt
    28321 cccaatcgta cttcttagta aagtaatgaa actgtcgatt ccttgaactg cttcatctgt
    28381 ttttttctgc caaatcaaaa atttcaagct agtcagcgta ttataaataa aatggggctg
    28441 tatctgtgct tgcatagttt ggatttcaag cgaacgtttc ttcttttcgt cttggatcgt
    28501 ctgttcataa tgatgctgag cattacttag caattgattg atcgtattcc ctagcaattg
    28561 gacttcatgg cttccttgta caggaacagt agcttttaag ccatcttcct ctagccgttt
    28621 tagcgaatca atcaagcggt agatcgattt tgtgtgtcga tccaaataca taaataccaa
    28681 tgagccagca aaagcaagtg tcacgatatt atacaaaata atcggaaaaa tcacgcccat
    28741 ttggttagat aaagaatgaa gatcgacttg actgagtaat gtacaatcct ggcggtacag
    28801 aggaagacgg gtcaactgct gtccatttga aatcgttgtt tcacctactg ttagtttttt
    28861 gaaaatcatt gatcggctcc caattgtatt ttcttcattt gatgcgatga tcgtctgttc
    28921 ttcgttcatg aaggagatct tcgatatctc aggatttact acagattgaa aaagattcgc
    28981 tagttgcttg gatgagatcg ataaaacagc atatccgtaa acgtgattca atgtattttt
    29041 cagttttttg acaaagaaga cgctgggtgc tttcttatcg cgaagagtca atccgtggtg
    29101 tgcaaaaagc atttgtgtat cagcagcacg ttcattcact ctctgagcaa tcgcagattg
    29161 aaaaaaagaa tcggcagata cggcagtgag catgtcgttt ccgacaaaag ttcttccatt
    29221 ttctccaaag atcaatacat cgtaatcgat cattggatgg atttttgaaa gagagtcatt
    29281 cattttttgg attgttctta gttgctgaag ctgttccata tgttgggctg gatcattgga
    29341 aaaatagctt ttgacagctg gattagaatc aaaagcggct aatgtattct cgattgtatc
    29401 attcaaactt tcaaattcag attgaatctt ttttagtacc acatcattcg attgattgaa
    29461 cagctggata taggcatccc ttgatcgatg ataaataaac aaagaaatga cgatggcttg
    29521 cagaaaaaga ccgatgaaca aaatgaacag aagtttggca aagagttcat gctctttgat
    29581 tttttttctc attttacaaa agttccttta cggtattgag aaggtgtcat tcctgtctct
    29641 tctttaaaaa ctctggagaa ataacccagt tcggtatagc cgactttctc acagatttcc
    29701 gtcaaagtaa gccgtgtttc cgtcaaaaag agcttggctt tactgatacg gacttttttt
    29761 agatattttg aaaagttgat accaaatttt tcagtaaaga tggctgagag atagctatat
    29821 gaaaaatgat atttttcgga taaaagttgt aaattgattt ctttctcata attttcctgg
    29881 acgaactcgt agatcaaagt caagatatcg aaattgtctt tttttgcatt tgcagaaaag
    29941 tgggtgagtt tctcaagtgt ttctttgaca agaatagaaa aatcttcgaa atactcagca
    30001 tcggctaata aagaaggaag ggcgatcttg agcaaagaaa gttcttcatt cccaacatgc
    30061 tcgtcagcca aagcgttgag taatgcatag aaacgattga ttgcctcatg tttcaaataa
    30121 gctggatcaa taggctgttc caatatcgtc gtgaagaaat tctcaagttc tttgacagct
    30181 aaagcgtagt ctttatgaac gatttttgtt aaataactac ttgcttgctg ctcgtggttg
    30241 gttaataacg gaagaagttc atgctgataa gcaaggttct ttcccttatg atagaaacgt
    30301 tgtcctttgg tgcaatttct gatctcttgg aatatttcat tgatatcttg gattgcaaaa
    30361 gaatcagaaa caacaaaaaa atcacctgga aaaacttctt gacgaaactt ttgaacaaac
    30421 ttcctaagtg tatctttgga atcagtattg attacatagc cggattcttc cgaaaaggta
    30481 gaaacaggat aaatagtaaa cgaatcgtcg ctatccatca atgaatgggt gatcgactgt
    30541 ttttgtttag agccttgttt tgaactgaat ggccgttttt cggtatataa cagaaaaaca
    30601 aggtgtgttc aaaaagaaga gggtcaagca atggacgagt ttgtccagca atctgctgtg
    30661 aaagattctc gcagatctgc tcataacgat tggtgattgg gcttttgttg ggcttttttt
    30721 tgattttttg tgaaacggca gttaaggaat ttagaaaaaa atcaggactc aatcgaggct
    30781 ttaaaagata atcagcgacg ccttctttaa aagaatcttt aaccatatca aattcatcat
    30841 agctagagag gataaggatc tgtgtttcag gttgttgctg ttttaatagc cgcgataatt
    30901 cgattccatt taattcaggc atcattacat ctgtgaccac gatatcgatt gcatgtacca
    30961 aagaaaaatc aagcgctttc agcggactgg aaaaagtccc tattaattga aacccgtgct
    31021 cagaccaatt gatcaactgt ttcattccat ctaaaatcgt ctgttcatca tcgataagaa
    31081 ttacgcgtat tggcattttt ttacccgcct taagaatagt cttgtaattt aaaaatactt
    31141 atttctagga gaaaatgcaa ggatattttt attttaaaga aacctcacca tttcgatctt
    31201 tggtctagat gctaagatta ttccttttgt catagttgat ttgtattttt ttattatttt
    31261 aggagaaatt tttgaagtat ctgaataata aagaaaccgt tttcaaattt tggtatgatg
    31321 aatgtagcaa acgtaaacaa ctaatggatg gaaaaggagc ggataaaaat gaacatcaga
    31381 aagttaattg ctggagtcgt ttgtttagcg gcagcatcag gtttcttaac aggatgcgga
    31441 agtgctagta gtacagcaga caaagaagaa aaagtcactg tctgggcgtg ggatgagaca
    31501 ttcaatatca aagcagtgaa tgaagcaaaa aaagtttatg agaacgaaga aacagagata
    31561 gaagttgtta cgatgtctca ggatgatatc gttcagaaac tgaacaccgc tttagcgagc
    31621 gggaatacag aaggattgcc caatatcgtc ttgattgaag attataggat acaaggctat
    31681 ttgacttctt atccagatgc attcgctaat ttgtctgcta ttgtaaagga agatcatttt
    31741 gcaccgtata aatttgcggt aaacaaagta ggagataaaa tatacggtgt tcctttcgat
    31801 tcgggcgtaa cagcaaactt ctatcgtacg gatctgatgg cagaagcagg ttatacagaa
    31861 gaggatatgg agaatctgaa gtgggacgag tatattcaag tagcgcgaga tgtcaaagaa
    31921 aagacgggaa agaaaatcgc tgaagtcaat ccttctgacc ttggtcgagt aaggatgatt
    31981 atgcaacagg caggagaatg gtatacatct gaagatgggg agacagtcac gatccaagac
    32041 aatgcatctt taaagtatgg tcttgaattg tttgccactc ttttgaaaga agatctagtc
    32101 gaacaaacct ctgactggaa tgctggagta actgcgatac aatcaggagc agtagcttct
    32161 agcccaactg gcgcttggta ttcttcaacg atccaaggag cagaaaacca atctggaaaa
    32221 tggaagattg caccaatacc tgcacttcca gaaaatctgc aaaaagcgca agcttctaac
    32281 cttggcggcg ctggctggta tgtgatcaaa ggagtagctg gagaagattc agcgaaagat
    32341 ttcctagaag caacgtttgc ttcgaatgaa gaactgatgg gcactcttgc gaaagaaatc
    32401 ggactagtat ctacgatgct tagcgcgaat gaacaagaag cttatcaaga agcttctgaa
    32461 ttttacagtg gtcaaaagat ctttgacgat ttttcaacat ggacatctga aataccagaa
    32521 gtgaattacg gacatgagac ctatgcaatt gaagcagtcg tagctgaagc tcttcatcga
    32581 atcatcaatg gagaagagac agacaaggta ctagcagata cacaaaaaca agtagaagca
    32641 caattggcta attgatcggt ggtaaaaaag tgaatttctt cgctttttca tcagacaaac
    32701 gaaaagacaa aaaagatcac gtctgcctta cagatattgt ctttcttgtc ttttcatgta
    32761 gataatcaat gatagaattg gagggaaaag aatgaagcag aaagatttat tcaaaaacgg
    32821 gcatgctttt ttaatcttgc cagtcatttt gatatcaatc atggttttta ttccgatggt
    32881 tttggctttg atcacgtctt ttcaaagtgg tccccctgtc aatatgacat ttaacgggtt
    32941 aggtaattat cagcggatgt tgacagatgc aacttttaaa aaagcttttt ttaatacatt
    33001 cctgtattta cttgtacaag taccgatcat gttgtttcta gcacttttta tttccaacct
    33061 tttaaatgat aaaaagttga aatataaagg gttgtttcga accgctatct ttcttccatg
    33121 tatcacttcg atggtcagtt attctctgat catgaaaagt ctattttctc aatctggcct
    33181 tgtaaacaac ttgttgttgg gcattggtat gattgacaca ccgattggct ggttgactca
    33241 tccaatttgg gcgagagttc tgatcattct ttcgatcact tggcgttgga ctggatacaa
    33301 tatgattttt ttcctttcag gcatgcaaaa tattgattcg gagatttatg aagcagcatc
    33361 tattgacggt gcttctaaat ggcagcagtt tatcaaagtg acgatcccaa atttaaaacc
    33421 aatcattttg tttacttcca ttacttcgac gatcgggaca ttgcagcttt ttgatgaagt
    33481 acaaaatatt actggcgggg gaccagcaaa tgcaacgacc accctatctc aatacatcta
    33541 taatttgagt tataaattca cgcctaattt tggatatgcg gcagcagttt cctttgttat
    33601 tgtttccttt attgtgatat tgtcgataat ccaaacgaaa gtaggaggag aaagtcgatg
    33661 aaaaatatgg tagaaaaaga aacaatcgaa cgccccaacg tcaaaaaaca agcattagaa
    33721 cttcgttcga caattgggtc agtattaaag tatacagcat taagcatcct atcatttatt
    33781 tccattttcc cttttgtctg gatggttttg ggaatgacga atacacccgt ggatatcaca
    33841 tcgggaaaaa taaagattgg cagtaacttg atcatcaatt ttcaaaattt gttttccaat
    33901 gagctgaatt ttactcgttc cctttggaat tcagcgatga tcgctttggt gaccactgtg
    33961 tttgcattgc tgatttcgtc aatggcagga tatggatttg agatttatca aagtaaacga
    34021 aaagacctaa ttttcaatat tctactgcta tcgatgatgg ttccttttgc ggcattgatg
    34081 atccctttat atcgaatgtt ttcacaattg aacggaacgg ttttgggaat caacagtttc
    34141 ttggttgtca tcctgccatc tgttagcact gcttttttga tcttcttctt tcgacaaaat
    34201 gttaaatctt ttccaaaaga tctagtagaa gccgctcgat tagacggtct aaaagaacta
    34261 agtatttttt ttagagtgta tatgccgacg gctaaaaata cctatgccgc ggctgcaatc
    34321 atcacattca tgagtagctg gaacaattat ttatggccct tagtagcttt gcaatctcct
    34381 gataaacgga cggttccgct tgttttatct gctatgggtg cttcctatac accagactat
    34441 ggaatgatca tggctggatt agtcatcgct actttaccaa ctgccatcgt attttttgtt
    34501 ttgcaaaagc aattcgttca aggaatgatc ggctctgtaa aataaaaaaa cacaataagc
    34561 gcgttccttc aaagtcattt ttccaagtaa aaagatactt ttgggacgtg tgttatttta
    34621 tgttgagaaa aattaaatga taacgtttta agtttgtgct cgaaaactct ttcattttaa
    34681 ggtaaactta aagagtaaag gaggaggata catgctaaaa aattttaaag aagtgattgc
    34741 tgctatattg ccgatgactg tcctgattgt cattttaacg tttgtttttg caccgttaga
    34801 aggagaagac ctcgcttcat ttctggttgg tgcggcaatc atgatgatcg gaatgacgct
    34861 ctttttgttt ggagcagatt attctatgat ggaagtcgga gatctagtag ggaaatatat
    34921 gatcaaaaag aaaagtttga ccgttttggt cagtttggga tttgctatcg ggatcgtgat
    34981 cacgattgct gaaccttccg tgcaagtttt gggacaacaa gtatatgata tatctgacgg
    35041 agagattggc agagtgttgc tgattgggat cgtcagcgtc ggcactggag tatttctagc
    35101 ctttgcgctg cttcgggtcg tattcaagct atcctattat caattgatgg ctataggcta
    35161 cataggcgtt ttgatcgcct catttttcac cagttccgaa tttatgccga ttgcttttga
    35221 ttcgggggga gtgactactg gtccagtaac tgttccattt atcttggccc ttgccggagg
    35281 gatgactagt atgatcaaac aaaagaaaaa tgaaaatgac agttttggaa tggtcggtat
    35341 tgcttcgtta gggccgattc ttgccgtgat gattttgggg gtgatcttcc aatgagtttc
    35401 tggcagcaag tgatagatgg aatcgaaatc gttaccatgg aagtcatttt ggcagtggca
    35461 cctatcgtaa tcctatttgt tttaatgaat atcattagtt ttcgtatgcg caaaaagcgt
    35521 ttctttgaca ttatgaaagg tttcttgata acgactattg ggttgatcct tttcctgcac
    35581 ggagtcaata tggcttatgt accggtagga cagcatttag gcagtgctat tgcgggattg
    35641 ccttacaatt atatactggt tccccttggc tttttaatgg ggttcttagt agggtttgct
    35701 gagccggcga ttcatgtaat gatcaaacag gttgaagaat tgagcgaggg gagaatccga
    35761 tcgaaaatca tgctgatggt aatttcaatt gggatcggcg cagcagtagg attgtctatg
    35821 tggcgtttgc tcgtcggatt ctctctttat tatttcttga tcccaggata cgggctagca
    35881 tttattttag gacgaaaagt ggacaagatc tttttagcaa tggcttttga taacggtgga
    35941 gtagcaacgg gcccgatgtg ttcgacattt attttatcaa tgagcgtggc aatcgctgca
    36001 caaattgaag gaagagatcc gatcattgac gggtttggtg tggttgcaat gattgcattg
    36061 acaccaatat tatccacttt agtactagga tatatttata aacgaaaaga tgaaaaagac
    36121 agaatcgaaa aagaaagatt gcaaaaattg ggggaaagca aatgaaagat cttgtagcat
    36181 tgaatcttca catgattgtg acgatcgttg acggaggaat gggcgaagat gttatcgact
    36241 tttcaaaaga agcaggtgca gcaggcggaa cgatcttaca tggaagaggt tctggtgtac
    36301 atgattcagg gaaattttta ggtttggaca tttcgccaga aaaagatatt gtgttgacat
    36361 tagtacccga tagtttgacg aataaagtaa tggatgcgat tggtcaaggc atcaacatcg
    36421 atattccagg taatggtatt tgttttagta ttgatgtaga caaagtcatt ggtatcacta
    36481 agattcatca atatcgagaa attatcggaa tgcaagaact tttagatgaa aaaaacgata
    36541 gagaaaagtc tgaatcatag acaagcgttt gaagaggaaa taaacacaaa caagaaggcg
    36601 gatgagcgtt atttccgctt ttttgtttgt atttttctcg tgaatactta tgaaatagta
    36661 aatttttatg aaattctact ctaagcatca gactttcttt tcaaaatatg ctattttaaa
    36721 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
    36781 gagcgattta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
    36841 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
    36901 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
    36961 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
    37021 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
    37081 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
    37141 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
    37201 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
    37261 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
    37321 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
    37381 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
    37441 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
    37501 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
    37561 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
    37621 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
    37681 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
    37741 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
    37801 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
    37861 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
    37921 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
    37981 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
    38041 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
    38101 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
    38161 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
    38221 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
    38281 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
    38341 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
    38401 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
    38461 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
    38521 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
    38581 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
    38641 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
    38701 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
    38761 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
    38821 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
    38881 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
    38941 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
    39001 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
    39061 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
    39121 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
    39181 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
    39241 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
    39301 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
    39361 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
    39421 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
    39481 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
    39541 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
    39601 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
    39661 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
    39721 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
    39781 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
    39841 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
    39901 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
    39961 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
    40021 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
    40081 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
    40141 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
    40201 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
    40261 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
    40321 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
    40381 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
    40441 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
    40501 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
    40561 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
    40621 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
    40681 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
    40741 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
    40801 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
    40861 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
    40921 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
    40981 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
    41041 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
    41101 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
    41161 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
    41221 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
    41281 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
    41341 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
    41401 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
    41461 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa tagttcctca
    41521 tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa
    41581 agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa aaaatagctt
    41641 ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa caccgtttac
    41701 cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca tataaataca
    41761 cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt atttattatt
    41821 aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat tttcccattt
    41881 tcctatggta aactgacaaa gttgagaatg ttagaacaga tcgtttagga ggaaacagat
    41941 gtttacgaat gaaataaaaa tcatgcttta tgtggacgat gtagaaaaaa atgcaacgtt
    42001 ttggagagca gttggctttg cggaaaaaga tcgtcaagaa atggatggga cgcttataat
    42061 tgaagtagga gttgaggaca gtcaaacctc atttctgtta tatgatcgag catttgttga
    42121 gtcccattca cctggcacag ctactagtgc cccatctttg atgttttaca gtaaagatat
    42181 ctttggacta tataaaaaaa tgcagacgca atcagtcaca ttaggtgata tggtacagct
    42241 tggagaagaa tatgtcttta actttgctga tcccgatggc aactactttg cggttacagg
    42301 taaataatag aaataaagac tttgtttttc tgtgcgaaac aggaaagcga agtcttttta
    42361 attcaaataa taatattatg taaacaaaaa actttccatg cgtaattata cacaagcaaa
    42421 taaatcgtca aatgcgaacg ccttctttat actgtttagg aacgaaaaga aggaaggaag
    42481 aaatacatgg attatcaagt actgctttat tacaattata caaaaatcga agaaccagag
    42541 gaatttgcca aaaatcattt agccttttgc aaatctttgg atcttaaagg tcgtattcta
    42601 gtagctgaag aaggaataaa tggtactgtg tctggaaccg ttgaaaacac gactgcctat
    42661 atgaaagcaa tgaaagctga tcctcgattt gctgatacga tgttcaagat cgatccaagc
    42721 gaaggacatg cctttaagaa gatgtttgta agataccgtc cagagcttgt aagtttaaag
    42781 ctagaagagg acattgatcc aaaccaagtg acaggtgcct atctttcacc gcaagaattt
    42841 aaagaagcta ttttagatga acagacagtg gtgattgatg cacggaatga ttatgaatat
    42901 gacttgggac attttcgagg ggctgtacgc ccagatatac gcagttttcg agagcttcca
    42961 gactggatcc gcgagcacaa agaagaattt atggaaaaac gggtagtgac ctactgtact
    43021 ggtggcattc gttgcgagaa gttttctggt tggcttgtcc gtgaaggatt caaagatgtc
    43081 ggacagctgc atggcggtat tgctacttat ggtaaggatc ctgaagtcca aggagaatta
    43141 tgggacggca agatgtatgt gtttgatgaa cggatcgctg tcgatatcaa ccaagtagat
    43201 aaacaaatcg tcggtcgcga ctggtttgac ggaacaccat gtgaacgata tatcaattgt
    43261 agcaatcctg agtgcaatcg tcagattctt gcttccattg aaaatgaaga aaaacattta
    43321 ggagcatgta gcatagagtg tgcgaaacat ccgcgcaatc gctatgttca agaccatgga
    43381 atctctccag aagaagcaga actgcggttt acagctttaa ttaaatagaa aacaatagtt
    43441 ttgattgtcg accatttcca atatgcgcta tactagcgtt gaggatggtg atccacatga
    43501 aatcattgat ttatgctatt ggggatgtcc atggcaaaca tgagcttttt gaaaaactta
    43561 ttcactatta tgatccaaag atccatcagc ttgttttatt aggggatctc aatgatcgag
    43621 gtcctcgtac aaaagaatgt tttttattag gaaagcaatt agtcgaagaa acaggagcca
    43681 tttacctccg gggaaaccat gaagaatatt ttttgcaatt tctgcaatca ccggaggact
    43741 ggtatgcgcc ttatatgaga aatggtggaa aagaaacgtt tgaaagcctg attcacccag
    43801 gggcatcgga ggaatactcc ccaactgaaa tctcgatgat gatccaatcg agatattcag
    43861 aactgattaa atttttagtc cagcgcccct tgtattatga atgggaaaat tatctttttg
    43921 tccatgccgg tgtggatttg acaaagaaag actggcgtaa gacaagtcta agagacttta
    43981 tttggataag ggaaccattt catgaaggga aaaacaatac aggtaagaca attgtatttg
    44041 gacatacgat tacaccaatg ctccatggag atatgcagac aacagacctc tggattcagg
    44101 atcataaaat cggaatggac ggtggggctg tattcggagg gtcattgcat ggggttgttt
    44161 ttgacaagga aggtattctt caagatattg aatatcagaa caacgaagga ccttggcatg
    44221 gaatctgact aatggaaaga atgaaggagc tgtgactttg ttgcggctct ttttattttt
    44281 atagagaata ttgtttcttt cagtagttta acccaggata aaaagtatga tagaataaag
    44341 aagcaatttt tagcagaaaa gaggcatttt aatgacggaa aatttgaacc agacgatcat
    44401 tcagcttgta caaaaagaac tttcagacta tcgtcctaag cagttgacta ctgtacttaa
    44461 tttgttaaat gaaggaaaca ctgttccttt tatcgcgcgt taccgaaaag aaatgactgg
    44521 aagtcttgat gaagtccaga ttcgtgaaat cgaagagcgg tatgcctatc ttgaaaactt
    44581 agaaaaacgt aaaactgaag tgattcggct aatcgatgaa caagggaaac tgactcccga
    44641 gttagaagca gaaatcaccc aagccgtgaa aatgcaacaa gtggaagatt tgtatcgtcc
    44701 atacaaacaa aaacgacgga caaaagcaac gattgctaaa gaaaaaggac ttgaaccact
    44761 cgcgaagtgg ctgatgcagc ttacagatgg agaggtgcaa tctgaagcag aaaaatatat
    44821 tgacaaagaa aaagaagtct cttctgccga agaagcgttg cacggtgctc atgagattat
    44881 tgctgaacaa gtcagcgata atgcaaaatt tcggacttgg attcggtctt atacgtataa
    44941 caaaggtatg tatgtcagca atgtcaagga tgagcaagca gatgaaaaag gcgtatatga
    45001 aatgtattat gactttgcag aacccgtcca taaaatggtt tctcatcgaa tattagctac
    45061 taatcgtgga gaaaaagaag atattctgaa agtattcttt caagtagatg aagcagcaat
    45121 tttagcttac ttggatcgcc aaatagtcaa aaatcctgcc tctccttctt cttcattcgt
    45181 cagagaagcc tatcaggata gttataaacg ctttattcag ccagcaatcg agcgagaact
    45241 gcgcaatgaa ttgactgaaa aggcagatga gcaagcaatc gctattttcg gcgaaaacct
    45301 ccgtaatctt ttgttgcaac cgccactaaa aggtaaagtt gtcctgggat ttgatccggc
    45361 ttatcgtact ggatgtaaac tagcagtcgt agatgcgaca gggaaagttt tagcaatcga
    45421 agttatttat cctcataaac ctgcagcgca agcaaaaaga gaagctgctg gaccagcttt
    45481 tatccaatta attaataaat atcaagtaga tatggtagct atcggaaatg gtacagccag
    45541 tcgggaatct gaactttttg tggctgagca gttgaaatcc gccgaccata aaacctatta
    45601 cgctatcgtc aacgaagcag gcgcttctgt ttactccgct agcgaaattg cacgaaaaga
    45661 atttccgcat ctacaagttg aagaaagaag tgctgtttct attgcccgtc gcctgcaaga
    45721 tcctttagct gaattagtca aaatcgatcc taaagctgtc ggagtaggcc agtaccaaca
    45781 tgacgtttct caaaaacgtt tggctgaaca attggatttt gttgtggaaa cagcggttaa
    45841 ccaagtaggt gtggatgtga atacagcaag cccgcagctc ttgcagcata tatcaggatt
    45901 gaataaaaca actgcccaaa acattgtcat ttatcgtgaa gaaaacggag aattcaccgc
    45961 acgaactcaa ttgaaaaaag tgccacgctt aggaccaaaa gcatatgaac aagcaatcgg
    46021 attcttgcga gtccctggtg ggaaaaacat tttggacaac acaggtatcc atcccgaaag
    46081 ttattctatt gcaaaagaaa tattaacttc agtccaactt tcagaaaaag agcttggtac
    46141 agaagaagca gtagaaaaat tgacacgatt atccgtagag aaactggctg aaagcctatc
    46201 agtcggagaa gaaacgttag ccgatatttt agctgggctg acacaacctg gacgagatat
    46261 gcgtgatgag atgccagcgc ccttattacg tacagatgta ttgagtatgg aagacttgaa
    46321 accagggatg gaattgactg gaacggtccg taatgtcatt gacttcggcg catttgttga
    46381 tatcggtgtg aagcaagacg gacttgtcca tatatcgaaa ctcagcaaaa aattcgtcaa
    46441 gcatcctaca gatgtcgtgt cagtaggaga tatcgtaaca gtttggatag aacaagtcga
    46501 tacgaaaaaa ggcagaatca gtttgacgat gctttcccct tatgaagagt aacaatgagg
    46561 agtaacaaaa attgacacaa gaagaactgc agcagttagt agaagagata tcattaaaaa
    46621 gcttccagct tcctttcaag caccaagcaa tgttcaatcc acgcttacgt acaactggcg
    46681 ggcgctatca tttaaacgat catcatttag attttaatgc gaagctattt gaagagtcag
    46741 acgaagagac gattgcagga atcatcaaac atgaactttg ccattatcat cttcatctag
    46801 ctggaagagg gtatcagcat aaagatatgg atttcaagta tcttttgaaa aaaacaggag
    46861 ggttgcgcta tgcaccagcc ttgacgaaga aacagataaa gatggagtat tatcgatgcc
    46921 aagattgttc tgccacgatc tgccgcaaga gaagaatcga tgtacgcaaa tatcgttgtg
    46981 gaagatgtca tggagaaatc aaatggattg agacaaaaag agaagacttt aatgaagcac
    47041 aaaaaatcag atgaaaggat agaaggcctt tggaaaaaag tgagcagagg aatctaaaag
    47101 actggaatca gctattaaat tttttagccg cacctgaaga gggaaatttt gaggaactga
    47161 cggcacctac acttatttta gctggaaact gtcttcctat cttagctgat aaagcagcac
    47221 aaatgtattt aaatggccaa gtagatcaat tgtttttggt cggaggggtg gggcatgcga
    47281 ctagaatcct ttatgagaat tttgaaaagc aaggatttca ttttgaagat ggcatgagtg
    47341 aaagtgaaat ctgtcgtcag tatctaaaag aagtctatga tttgcccgat aaggcttttc
    47401 tgatagaatc gaagtctaca aattctggag agaacgccac tttttcactg gagattcttc
    47461 attccttagg agctgtacca gaaaaaatct tattgatgaa tgatccgaca ctgcaacgca
    47521 ggactcgagc aacttttgag aaagtatggc aaaatgaaca aactattttc gcgaatgctg
    47581 tgccatttgt gccggaaatc cttcactttt ctgaagagat catctttaca gcaaaagaac
    47641 tgaatcatca atggcctaag gaatatttcc atgcgctagt attaggagaa atggaacgtc
    47701 tccatgacga tgagaacggc tatggtccga aaggaaaaga ttttattcct cacattgata
    47761 tatcagagga agtttggtct tcttacacca gaattaaaga gtcaataaaa acggattttt
    47821 ctcgtacttg accattttag caagcgaatc ctcctttcca aataaatttg gttgaaattt
    47881 tcaatcgttt ataagataat gaggagcgtg ttgaatgtaa tagctaaaag aatggacgct
    47941 agataagaga agaggattca aatggaaaat caaaataaat tgtatcattt tgttggtatc
    48001 aaaggttcag gaatgagctc cttggctctt gttttacatg aacaaggtct aaatgtccaa
    48061 ggatcagaca ttgaaaaata tttctttaca caaagagatt tagaaaaagc aaatatcacg
    48121 attctgccat ttaacgcaga taatgtaaaa ccagggatga cgatcattgc aggaaatgca
    48181 tttcctgatt cacatgaaga aatccagcga gcaaaagaat taggtttgga agtgattcgc
    48241 tatcacgact ttattggtca ttttatccaa aattatacga gtatcgctgt aacaggctct
    48301 cacggaaaaa caagtacgac tggactgctc tctcatgtat tgagtggtgt ccgtccaaca
    48361 agttatctaa ttggagatgg aacaggacat ggtgatccgc aagcggaatt cttttcattt
    48421 gaggcctgtg aatatcgccg tcatttcctt gcctattcac cagactatgc aatcatgacc
    48481 aatatcgatt ttgatcatcc ggattattat acaagtatcg acgatgtatt tacagctttc
    48541 caaacaatgg ctggacaagt gaaaaaagct atttttgcgt atggtgacga tgcttattta
    48601 cgcaaattaa aagcaaatgt gccgatttat tattatggtg tcacagaaaa cgatgatatc
    48661 caagcacgaa acatcgaacg cacaacttct ggttctgctt ttgatgtcta tcatggggat
    48721 gaatttgttg ggcacttcac tgtaccagca ttcggtaaac acaatatctt aaatgcttta
    48781 ggtgttattg cagtagctta tttcgaaaaa ctggatctga aagaagttgc agaagaaatg
    48841 ctgactttcc caggagtaaa acgtcgattc agtgaaaaga tcgtagcaga catgaccgta
    48901 gtcgatgatt atgcgcatca ccctgcagag atcaaagcaa cgattgatgg cgcacgccaa
    48961 aaatatccag ataaagaaat aattgcagtt ttccaacccc atacgtttac gcgtacgatt
    49021 gcattgatgg atgaatttgc agaagcactt gatttagctg ataaagttta cttatgcgat
    49081 atttttggtt cggctcggga agaacaagga aacgttaaga ttgaagacct tggagcgaaa
    49141 atcaaaaaag gtggagaagt catcaaagaa aataatgtat ctccattgtt agattatcat
    49201 gatgcagtag taatcttcat gggtgctgga gatgttcaaa aatttgaaca agcgtatgaa
    49261 aaacttttaa gcagcacgac gaaaaatgta ctgtaataca attactgcag tgtccttata
    49321 aaaatagaaa gagggggagt ggcaaaaatc ttgccaagcc cccttttttg caacttatga
    49381 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aatcaaatca aaaacatgag
    49441 aagctgtttt ttcttggctg ttcttattat ttgatgcagg acagcttttt cacgacctct
    49501 gtaaactata ggaatctgtt aaatcaaggg agcagaactt gccttttacg ctacttttgg
    49561 tacaataatg tatgattaaa aataaactgg agggtttcta tcttgaacat aggtaagccg
    49621 agaaaactag gaaaaacaat aaatgaaatc gaggaaggcg actcgttatc cttaacagaa
    49681 tctattgaag ataaccagct tttgctgtat ttgggattga cgaatgatgc aaatcctttg
    49741 tatatccaac atgactttgc acaaaaaaca gaatatcaac agccaatcgt tccatcagtg
    49801 atgctgatgg ggatcatcac aagtgcaatt tcaaagcatc ttcctggacc aggatcacat
    49861 gttgtcaatt tttctgtcaa ttttattgaa ccggttttcc attatgaaac actgactttt
    49921 cagtttgagg tcataaaagt agataagatg aaggatgtgg tgacgatttc tgtagaagcg
    49981 gagaatacga acgaagatcg tgtgttggat gctgtcgtta tggtccaacc gccacaagtt
    50041 cctgaattgg aaatagcaat cgaaagtgaa ggtgaattga atgaataatc caagtacatc
    50101 aatgtcaggt atcaatcgtt tttatgcaaa agtttatgga tttttaggta tgggacttgc
    50161 ccttagtgca gtcacttctt acttggctct ttgggtattt cctttgcaat tagcaacttt
    50221 tatcaataat tttccactag gctttgtggg tctgtggatc gttgaactga ttttagtaat
    50281 ggttctaggc gtaaaagcac aaaagaatcc gagcttagca atcggtggat ttattgccta
    50341 ctctcttttg aatggcataa cattagcggt tactcttgca tactacgata ttggaacagt
    50401 aacgcaagct ttcttgacag ctactttgat gttcatgggg atgtctgttg tcggagtaac
    50461 aacaaaaaga gatcttagcg gggttggaag agcaggacag gcagctttaa tcggagtgat
    50521 cattgcacta gtcttgaaca tcttcatttt gagaagtagc gtagttgagc tgttcatctc
    50581 cctactgtta gtcgtcatct ttgcagggat tacagcttat gataaccaaa gcatccgtaa
    50641 tatctatgtc cagacaaacg gaacagcaca tagtggaatt gctgtattca tggcattgaa
    50701 gctgtatttg gactttatca acttgttctt ggcgtttctg agaatctttg gacggaacaa
    50761 ctaaaaaaga aaaaaattca tcagttgggg ctataccgaa ttatttggta tggtcccgct
    50821 ttttcttttc gcattccgca ggattctttg ttagaatgaa taagaacttt acagtaagga
    50881 gttaagaaga tgacaaaaaa taaattatta ctcgttgatg ggaacagtgt ggcttttcgc
    50941 gcattctttg cgcttcacaa ttctcttgaa cgtttcaaaa atagaaacgg tcttcataca
    51001 aatgcaatct atgcattcaa tacgatgttt gaaaatgtta tgcaaaaaga gcaaccgact
    51061 catgttctgg ttgcgttcga tgcaggaaaa acgacttttc ggacagaaat gtatgcggag
    51121 tacaaaggtg gaagatccaa aacacctggc gaattcaaag aacaaatgcc atatatacgt
    51181 gatttgttga caggactagg ggtacagtat tacgaattgc ccaattatga agcagatgat
    51241 attatcggta ctttggcaga aaaagtagac aaagatcaat ttgatgtcgt cgtgctttca
    51301 ggtgatcggg atttgactca attagctagt aaagaagtaa aagtggatat cactgtaaaa
    51361 ggtgtcagcg atatcgaaag ctatacacca gaacatgtag cggaaaaata tgatgggttg
    51421 acgccaaaac agattattga catgaaggga ctagccggag atgcctctga caatatcccc
    51481 ggtgtgacta aaatcggtga aaaaacagct atcaagctat tgaaacaata tggctcagtc
    51541 gaaggaattt atgaacatat cgatgaaatg aagcaaagca aaatgaaaga aaatctgata
    51601 aatgacaaag agcaggcttt cttatcgaaa aaattggcga ccatcaatac ttcagcgcct
    51661 gtggatgtct ctatcgactc attgaagtat gaagggaaaa atctcgataa actcgttccg
    51721 ttttataaag aaatggattt caatcagttc ctttctaaat tgaatatcgt agaagaagaa
    51781 gtaaaaatgg atgatatttt gtttgaagtc gttcatgaat tcaaagagga aatgtttact
    51841 acggatatgg cgttgtacgt ggaaatgatg ggcgacaatt atcatacaga ggaaatcgtc
    51901 ggagtagcgt gggggacaga aaagaaaatt tatgtcacga acgatctatc tgtattcgaa
    51961 aaccgagcgt tccattcttg gatcactgat ccgactcggc tgaaaaaagt atatgatgcg
    52021 aaacgaactt atgttgcttt aaaccgctat actggaaaaa cgaaaggaat cgattttgat
    52081 gtcttgctag gtgcatacct tctcgatacg aatgaaaaaa gcacagatat cgaaggaata
    52141 gctgctcatt acggatacaa cgatatccaa tcagatgaag ctgtatacgg caaaggggcg
    52201 aaaaaaggtt taccagaaga agaggaactc ttttttgctc atttagcgcg aaaagtagct
    52261 gcaatcaatg cgttgacacc aaaattgagc caagaactgg cagaaaaaaa ccaagaagat
    52321 cttttccgga aaatggaact gccattgtct atcattttgg cagagatgga aataagcggg
    52381 atcaaagtag atgcgactcg cttacaagaa atgaagggcg agttctctgc tcgcttaaga
    52441 gagatcgaac aaaaaatcta cgaagaagcc ggcgaagaat tcaatttgaa ttcaccaaag
    52501 caattaggag tgatcttatt tgaaaaaatg ggattacccg ttatcaaaaa aacaaaaact
    52561 ggatattcca cagccgtaga tgtactggaa cagcttcgtg aacaagcacc aatcgtagag
    52621 gatatcctca cctatcgtca aattgcaaaa attcaatcta cctatgtcga gggactgctg
    52681 aaagtgatcc aatcagatgg aaaagtgcat acccgttatg tccagacatt gacccaaaca
    52741 ggacgattaa gctctgttga tcctaatttg cagaacatcc cgattcgatt agatgaaggg
    52801 agaaagatac gtcaggcatt tgttcctaga gaaaaagact ggctgattta ttcttctgac
    52861 tattcacaaa tcgagttacg cgtacttgcg catatctcaa atgatgaaca tttgaaagct
    52921 gccttcctag aaggtcaaga tatccatgcc agcacagcga tgcgtgtatt tggaatcgaa
    52981 aaggcagagg atgtcacacc aaatatgcgt aggcaggcaa aagcagtgaa ttttggtatc
    53041 gtgtatggca tctctgatta cggactttca caaaatctag gaatcagccg aaaagcagca
    53101 cagcaataca tcgatacgta ctttgaaaaa tacccaggtg tcaaagaata tatggaaaga
    53161 atcgtacgcg aagcaaaaga ccaaggctac gtcgaaacgc tgtatcaccg ccgtcgatat
    53221 ctgccagaca tcaattcaag aaattacaat atccgttctt ttgcggaacg aacagctatc
    53281 aatacaccaa tccaaggaag tgctgctgat attttgaaaa tcgcgatgat cgaattggat
    53341 aaacgattaa aagaaacagg tcttcaagct acgatgctgt tacaagttca tgatgaactt
    53401 gtcttcgagg taccggaaaa agaacttgaa tcattagata aattggtgaa ggaagttatg
    53461 gaacaagctg tttctcttca tgtaccactg atcactgaca gcagttgggg aaaaacgtgg
    53521 tacgaagcaa aataaacatt gtttaagaca gagcaatata atgaaggtga aaagaaaaaa
    53581 tgccagaatt accagaagta gaaaccgttc gtaaaggatt ggaacggtta gtagtaggaa
    53641 aaacgattca aaaagttcag gtcttgtggc ccaagatcat cgagcaacca gagacaccca
    53701 tctttgaggc ttctcttgtt ggcgaaacca tccaatccat tggacgtaga gggaagtttt
    53761 taatttttca tctcgatcat tgtgaactga tctcacactt gcgaatggaa ggaaaatatc
    53821 aatttacgaa agaaaataca ccaatcgata aacatacgca tgtacttttc ttttttgagg
    53881 atggaagcca acttcgctac aacgatgtac gaaaatttgg tcgtatgaca atcgtcgaaa
    53941 aaggagcaag tgcaacttac cgaggaatca tgaaattggg acctgagcct ttgccagata
    54001 gcttcttatt agcagatttc gcaaatggac tgaaaaagtc ccacaaagca atcaagccat
    54061 tgctgctaga ccaacgtcta gtgactggtc taggtaatat ttatgtagat gaagcattat
    54121 gggaagcgaa gatccatcca gaacaaccgg cgaacacact gcgccccaaa gaggtagaac
    54181 aattacgtct atcgatcatt gatgttttgg atcgtgcaat agaagccgga ggtaccacga
    54241 ttcgcagtta tttgaatgca ttaggagaat caggcggatt tcaagtagca ctgcatgtct
    54301 atcagcaaac tggcaaacca tgtatacgtt gtggaacgcc gatcgtgaaa acaaaagtgg
    54361 cacaaagggg gacgcactat tgtccgaatt gtcaaaggct aaaaatcgca aagtaggatt
    54421 tgttttaggt ttgacgggtg gaatagctac cggtaaaagt acggcagcca aagtctttca
    54481 gtctcatgga tttcctttga tcgatggcga tgtgattgcc agagaaactg ttgagcctgg
    54541 aacgcttgct ctgaggaaaa ttgtatcagt gtttggccaa gaggtattgc agcctgatgg
    54601 gcaactagat cgagggaaac ttgggatgat tgtttttcca tcaaaggaaa aacggcaaaa
    54661 acttgatcag ctattagatc cgtttatccg aaaagcgata aaagatcaaa tcgcctctct
    54721 aagttccaat catcctttag taattgtaga tatcccattg ctctacgaag gtcattatga
    54781 ccactatatg gatgcagtag ctgtcgttta tactacgcca gaaactcagc ttcagcgttt
    54841 gatgaaacgt aatcaactga cgctagaaca agcgcagcag agaattagta gtcaacttcc
    54901 aatcgaagaa aaaaagcagc gtgcggatat tttgttcgac aacaatggaa caaaagaaaa
    54961 acttgtggga caaatcgaaa attggctttt tgctaatcgc tttctttgag tatctgtgtc
    55021 aattttgcta tcctgagtat atagaaagtg agggatagcg atgggatcat taaaaaatca
    55081 aaaggataaa gtcgtaggta acgcaaaaga aaaaatcggc gagatgctca ataaagaaaa
    55141 tctaatcgat gaaggtcgta cgcaatcaga aacagcagaa gaaaaagaaa agcagtacca
    55201 agcaagaatc gatgaaatag aagaccagca ggcagaagaa gaagcgaagc ggcaagattt
    55261 gactcaagaa cgaaaaaatc cgacacctga tcgtagtaaa acaccgctcc cagaaagtga
    55321 ccacattccc gatgagcaaa aaatcgagga acagcgaatg aaacactata caggaatcga
    55381 agagaagtta taaaatagta aaaaatcgag atgtgacttg aagcagatga gaaggtgttc
    55441 atctgcttca agttttttgt gctagatgac taaatcagct tttgtgtaag ttatttctca
    55501 gtaatcaagg tgatcagtat tggaaaattg aaatttagta aggacagggg acacaattac
    55561 gcatgaaagt agaaaaaatt gttcttatat ccgtgttttt tgggtaggac agtcgcgttt
    55621 gtgatttgtt tcgtgttata atacaactag ttgtaaagaa agacacatcc tttatataaa
    55681 atgcgatgca agaggtgaga caaaatgaga tgtcccagat gtcaacataa taattcacga
    55741 gtaatcgaca gccgtcaagc agatgatgga cgtgcgatcc gtcgccgtcg cgaatgtgag
    55801 aattgttcgt tccgattcac tacatttgaa cgaattgaag ctgctccgtt attagtaatc
    55861 aagaaaaacg gggaacgcga agagttcaat cgcgataaaa ttttaagagg actcatccgt
    55921 tcagcagaaa aaagacctgt agctatggaa caaatggaac aaatcgtcaa ccatgtcgaa
    55981 aaccgcgtac gcagtctcgg agaaaacgaa gtatcgacga atctaattgg tgaatatgtg
    56041 atggaagatt tagttgattt agacgaaatc gcttatattc gttttgcaag tgtttatcgc
    56101 cagttcaaag atatgtctgt tttcttaaaa gagttgcaag atatcgtgga taaagcaaaa
    56161 gaaaataata aagagaataa taaagaaaac aattaagaaa caaaaaggag gcatttcctt
    56221 ggaaaatgct tggaaagagc ttcaaccaaa aaatatttac caaggaagaa aagcggctcc
    56281 gctgagagaa gacagcaaga acgccttgct gtatctttat cagccactaa tcggcggaga
    56341 agccttgagt atctatttca ccctgttatc agaaatctct caagaatctg gcaaaggtcc
    56401 tgaagggatg catgcagatc tgcttagtag tctaggctgc ggtatcccgc aattttatga
    56461 tgcaagaaaa aagctagaag gaatcggctt actggatgtt tattttaaag aagatagtga
    56521 tctgggacct cgttttattt atgagctgtt agaaccactc attcctaaag catttttcaa
    56581 agactctgtt ctggcttttc ttcttctgga aaaagttggt gaacgacgat tccagaagct
    56641 tacccaattc tttgaaccta aaaggcatac agcagaggga tatcaaaaaa tcacaaaaaa
    56701 atttttagat gtttatcgct tcaatgaagc agtgtacgct gctaatcaag aaaacatcga
    56761 atcgctgaat aaatcttttg aagaatctga atcagtagca ttacttgaag cagattcgac
    56821 attcgattgg cagtttttga atgattggct ggcaaaaaaa catattgcaa gtcttgatga
    56881 tccaatcatc aaacaagtcg acatgtatca tcagctttac ggtttcgatg aattgacact
    56941 tggcgaactg atcagtcaat cttatgactt tagtgaacaa aaagtatctg aaaaagaact
    57001 gcaaaaagcc attttggcaa tgcagagacg tccggtgaag caaacaaaag aaacagttgc
    57061 ggtttctgaa aacagtaatg aaccctcgtc aaacgaacat ttgacaaacg cagcgcttca
    57121 gctgataaaa gaagcacaga gcattccacc gatgaaatat ctggaagcaa tcaagtcaga
    57181 aaaaggcgga tatgtttcta aacaagaaaa ctggttactg caagatcttg tttctcaatc
    57241 aggtctttcc agtagcgtga tcaatgtttt gctgaattat gtactagtga tcaagaataa
    57301 tgctagctta aatgccagtt atgtaaatac agtggcaaat gaatgggcac aaaagaaaat
    57361 cgccacagca gaagaagcga tccagcacat tcggcaaata agtaatcaag caaaacaatc
    57421 aaaacaaaag aagcaaacaa attatcaaac tggcaagcga aatgttcgac gggaaaagct
    57481 tcctgattgg gtcaaccagc caaaagatga aaaacagatc agcagcgaga aaaaagcaga
    57541 gattgaccgc cgttttaaag aatacctggc aaaaaaggag ggtgatatct agtggaagac
    57601 gtaggcaaag aattgaagag gatcatcagc aaacgcaatt atcaagaaaa gtatgctgaa
    57661 atgatcgctg aagtcttaaa tgatgcggat gttcaagctt ttctaagcgc acaccaagaa
    57721 gaattgacac aagcggatat tgaaaaaagt tacgctaaat tgtatgaatt cgtgcaagaa
    57781 aagcgtaaat atcaaaaaaa cgatccaacg atgatcgctc ccggctatga gccgaagctg
    57841 acgttgaatt ttcattatgt ggatgtcact tatgtaccaa cggaagcatt gttagcacgg
    57901 caaagacaag aagaaatcag aagccgagta aaagcaatgg atatgccaaa agatattcaa
    57961 tcggcttctt ttgaaaactt tgaacgtaca gatggacgag gatatgcgag cttagaagcc
    58021 ctagattttg tagagaaata tactgctgat ccaaaagggt atcataaagg actgtatcta
    58081 gtaggaagtt ttggtattgg aaaaacatat ttattaggag caacagcgag agaattagcg
    58141 attgctggat tcaccacgac gctagtccat tttccgacat ttgccgttga gatgaaacag
    58201 gcaatcggaa aagatcaagt ggcagaaaag ttagatgcag tgaaacgttc acctattttg
    58261 atgatcgatg acattggtgc agatgcgatg agtagttgga tacgagacga agtattcggt
    58321 gttatccttc aatatcggat gcaggaacag ttaccaacct tcttctcatc gaattttaca
    58381 atggatgaat tggaacagca tttgtccgtc actcaacgtg gagatgaaga gccgctaaaa
    58441 gcgaaacgga taatggaacg catacgttat ttgacaaaag aaatcgaaat gactggtcgc
    58501 aaccgacgca atggttgaac agttgacaag tccaactgac atttgaccta gtagtaaaag
    58561 caggtcagcg aatcattata tggacagaaa tgaccggaga caatcaccgc aacaagtaat
    58621 gcagaaactt aaacggagga ttttttatga gggctatttt ttctagtata tctgtagttg
    58681 gtctattttt tcttttagca ggctgcggta gcgcagatag caacacaggt tctgttgatt
    58741 cgattgatgc gggtcaaaca gtaaaaacaa gcagtacgaa aacggagaga caaagcatat
    58801 ttgtcggaac gattgaaagt atcactcaag tagaagcaga agaagaaacg cttcagttga
    58861 aactcgtcga tgtcatggcc aaagaagatc cagcgaatat gggaacgtca ttcagcaatg
    58921 acggagtgat cttaaatgct actgctgaaa aaataagcgt ggacataaat gaattgaaaa
    58981 tcggtgacaa agtccaattt acattagttg agatgccgat catgacgatg tctatcccac
    59041 cgcaagttcc tggagattcg attattgatg tttcattgaa caaataacca ataacatttt
    59101 ttcaaaaata agaaaatgtt gttttataga acgaaaaggt atatttttta aggagatatg
    59161 ggaatttttt tattcctagt ctccttattt tatttggaaa atgctataat tatctagaag
    59221 gagtgaagct atgaaccatt tagatttatc tcagcgctta gccgcagtgg gtgactttgt
    59281 ccctgaatcc gctcgtttag cagacattgg atcagatcac gcttacttac ccgttgcatt
    59341 gatattaaga ggaaaaatcg aatatgcagt tgctggtgaa gtcgttcaag gtccttatga
    59401 atcagcacgt aagcaagtca aaaaagatgg attagaagac cgtatcaccg tacgccttgc
    59461 aaatggtcta gatgctatcc agccacaaga tggtattaca gctgtcacga ttgcgggtat
    59521 gggaggttca ctgatccgag atatcctaga agctggcaag ttgaatcaac gcttaagcgg
    59581 acaagaacgt ttgatccttc agccaaacat cggagagcgt acattacgat cttggctgca
    59641 agaaaatcag tataaaatcc aatcagaaaa aatacttgaa gaaaataaaa aaatatatga
    59701 aatcattgta gccgaaaaag aacaaaaacc agttacttac aatgaaatgg agctgatgtt
    59761 cgggccattt ctgcttgaag agaaaagtga gatcttcaaa tcaaaatgga caagagagct
    59821 tcaacaaaga aaagctatcc gtgaacagct caaacaagca gctaatcaag aggcacgtca
    59881 aaaacaaatc gagcaggaaa tccaaatgat tgaggaggtt ttaaagccat gacaatcagc
    59941 ggacgcactt tcatccaaaa gtttgaaagc tattgtcctc agtggctagc tgaagaagga
    60001 gacccagtcg gactgcatat cggaacattg gataagccaa tccaacgagt aatgatgaca
    60061 ttagacgttc gtccagaagt ggtcgaagaa gcaatcaaga aaaaaatcga tttgctgatt
    60121 gctaaacatc ctccaatctt tcgtcctgta aaacggctgg ttactgatca gccacaagaa
    60181 aaaatgtatg cagatttgtt gaaacatgat attgccgtct atgcagcaca cacgaacatg
    60241 gatattattt gggatggact gaatgactgg ttttgtgaac ttctcggtat tgaagtggag
    60301 agttatttag taaagactca tgagattcat tataaaaaac tggccgttta tgtacctgtg
    60361 gatcatgcac agaaaatgcg tgaagtatta gctgcagctg gtgctggtac acaaggtgat
    60421 tataccggta caagttttac ctcgattgga cacggtcgat ttactccgga agctggtgca
    60481 caaccagcga ttgggaaagt agggaagaca gaacaagttc aagaggcaaa agttgaggtt
    60541 attttgccgg aaactatcga aaaacaagtg attcaagcca tgcggtcagc tcatccttat
    60601 gaggaacctg cttatgatct tttcgctata gatgaaccag tcgaaatgtt tgggttagga
    60661 cgagtaggtg aattgccgca agaaatttct atagaggcat ttgtagaaca agtaaaagaa
    60721 gcgttccaac tagatggact gagaatagtc cagccaaaaa atgcaaaatc ctctgtgaag
    60781 cgcattgcga tttgcggtgg aagcggtgaa aaattttatc cgcaagcaat cgcccaaaga
    60841 gcagatgtct atatcacggg agatatctat tatcatacgg ctcatgatat gcaaagcgct
    60901 gggttgattg caattgatcc cggtcattat attgaatcgt tatgcaagca acgatttatc
    60961 gagaaatttg aatcttggaa acaagaagaa aattgggata ttaacttttt cgtttctgaa
    61021 acaaatacaa acccatttca atttaattaa aaggagagaa tactatgtac gaaaatcttt
    61081 tgccacgttt tttacgatat gtcaaaacag aaacacgctc cgatgcaaca agcaaaacga
    61141 ctccatcgac tcagacacaa gttgcttttg cgcaagaatt gaaaaaagaa ttagaagagt
    61201 taggcttagc tgatgttttc tataatgaag ataacggatt cgttatggga acattaccaa
    61261 gcaatgttga tcatgaagtg cgttccattg gatttatttc ccacatggat acagcagatt
    61321 ttaatgcagt aggagtcaat ccacaaatca ttgaaaacta tgatggcgag tctacgatcg
    61381 tactagatgc ggaagaacgc tatacattga atacaaaaga ttttccaaat ttgaaaaatt
    61441 atgaaggcca cacattgatc acaacagatg gcagtacatt actgggagca gatgacaaat
    61501 cagggattgc ggaaatcatg actgcaatgg agatcttgat caataatcct tctatccctc
    61561 acggtaccat caaagtggct tttggtcctg atgaagaaat cggtgtcgga gcggataaat
    61621 tcgatgttga gcaattcgat gtagattttg cttatacagt cgatggtggt cctttaggtg
    61681 agttgcagta tgaaacgttt agtgctgctc aagcaaatat tacgatccaa gggaaaaatg
    61741 tacatccagg gacggcaaaa gatacaatga tcaatgctct acagttagca atcgattttc
    61801 ataatcagct tccagccgat gaagttccag aaaaaacgga aggatacgaa ggtttcttcc
    61861 atttgatggc attggatggg aatcctgaag aagcttctat gagttatatc attcgcgatc
    61921 atgatcgtga aaaattcgaa gcacgcaaag cacaaatcac acatatccaa gaagagttga
    61981 atcagcgatt tgatcaagaa cgaatcaaag tagatatgta tgatcaatat tacaacatga
    62041 aagaaatcat tgaaaaagat atgagcatcg tggaattagc gaaacaagca atgatcgagc
    62101 ttggtatctc tccagtgatc gaaccagttc gtggaggaac agatggttca aaaatctctt
    62161 acatgggtat tccgacgcca aatctatttg ccggaggaga aaatatgcac ggacgattcg
    62221 aatttgtttc tttacaagta atggaaaaag caacagacgt gattgtaaaa attgcagaat
    62281 tgaacacaaa gagttaaaat cgaaaaagaa cagcttatga caaggcgttc gtcccaatga
    62341 tggaatgtca tctgtctaag gctaaagggc aggacaatgg aattggttgt cccgccctct
    62401 tttttgaaga gtaaatagga ggtaaagaat ggaaaagctg ctagtttttt ataacaaaag
    62461 ttcagggaaa gatgagggtg agaaattagc acgctggttt caagattatg taaaagaaaa
    62521 gcagccagaa ttatatgtag aactagctga aactggccca tcgattgatg atgcggaatt
    62581 agtcaagaaa gcagaagcca tagaagctga tactttagta attataggtg gagacggcac
    62641 gattcatcat atcgtccaag cgttccaaaa aacattatct caataccatg tcggattact
    62701 tccaggtgga actgtcaaca accttgcacg tgttcttgag attcccctca aaaaagaaga
    62761 agctgctgac gtgatcctgg aaggcaatgt acggaaaata gactatggtc aagtcaatga
    62821 tgaagtcatt atctctacac tgacaatcgg aatcttagca gatacagcag tttggatcag
    62881 tcaagaagaa aaacagcgtt acggctcgtg gatctttatc aagaagtttt ttaagttatt
    62941 gctgaagaag aaaaaatatc atttggattt agaaacagac gaggagcatt ggaaaggaaa
    63001 atcccaactg ttgacagtca cgatgtctaa ctccgtgggc ggttttacaa attttgacga
    63061 ctcagcgacc ctagatgatg gaaaatttca tgtaacgatc gtaccttcct tagatatttt
    63121 ccgatttatt ttttatttgc ctagaatcat gagaggcaaa ttctatacga tccccggcat
    63181 tacttatttc acagccaaac gcatgaaaat ccaagcgcag gaaaaatctg tgggcactcg
    63241 aacggatgga gacacgacag atgatcttcc agttgaatta tctgttgtat caaaaggatt
    63301 aacagtttat tcaccaaaga aagaagaaaa agcttagaaa tagtagttaa cagaaagttg
    63361 gaagaagagt aatggatgta ttgttacaca atcctttgtg gttttacctt ttcattgtga
    63421 atttttactt attttgtctg atggggtatg ataaacatca ggctagaact agcggctggc
    63481 gtgttcctga gaataatttg atatttgtca gcctgttagg cggtggtttg ggaggattga
    63541 tctctcgaaa agttttccat cataaaactc ggaaaaagaa gtttactata ggattcgctg
    63601 caggtgtact tgttgatttg attctcattt attttttcca ttaaggagca ggagatgtcg
    63661 tctaaaggaa cgaaaactaa aatcattctg aatctgcttt tgctgattgt gatttttgcc
    63721 attatttatt atttaatcaa tcaatcattt gcagatatct ttgccgaatt gctgtctacc
    63781 agtgttgttg ttttggcagc ggctgttata ttagggacag tttaccaaat cgctgaaggg
    63841 cgctcaatca aagaaattgc tgaacctttc gcgccgaatt ttacaacgaa agatgggttc
    63901 ttgacctcta gctatattgc gttttaccga atcgtttcgt ttggtacagg aacgctgatc
    63961 tcggagattt atttttataa caaaaaagga atgaagctat cccagggagc aggggtgaca
    64021 gcactccata tgattatgta caaactggca gtgatcactt atgcattagc tggcttggtc
    64081 atccaattct ctctttttta ttctaatggt ccatcaatga tctggtttat catcgctggt
    64141 atccttttga cgatcgtgat tgttgccttt ttattggcga tgtccgtcag cttgaatgtt
    64201 caaatatttt ttgtcagctt atcgaataag ttatttaaaa gtgagcgttt gcggaaatgg
    64261 gtggatacat gcaatcagca gatctactct ttaagggaaa cggtccaaac cattatccaa
    64321 gacaggactg cgctattgcg gatttatcta tggaatatgt taaaacttgt attttggtat
    64381 gtacttcctt atttgattct gattgaaaac catcctaaaa tagattttct actgaccatt
    64441 tcgtttatca gctttgcagt agtgctttca ggggttattc ctacgcctgc tggtattggt
    64501 tcctttgaat ttgtctattt gttattattc agaccagttg ttggaacagt tgacgcagtt
    64561 tcttcgcttt tactgtatcg tttcagttcc tttatcttgc catttctcta tggatttgtg
    64621 tatgtgattg ctgaacggcg aagagtgatc aaagaagaaa taatagaagt aaaaaaagag
    64681 aataaagaaa atcaagggta ggtcttttat aagatctacc ctttttatca aatcaaagaa
    64741 aaacgttatg gataagataa ttttacgttt gtttggctct ttttttatat acatacaatc
    64801 aattttgttt ttttaagatt tatataagtc gagaaaaaaa gtcaaaaaac tatgtgtata
    64861 ttttgaccaa aattgaccaa agcgatataa tagtttttgt aaagatcaaa gaaataagtg
    64921 atcttacctt taattaggag ggtatacctg tatgaatatt gagaaaatga ctacgacgct
    64981 tcaagaagcg attgctgaag ctcaacagat tgcggtcact cgaaaacatc aagatatcga
    65041 cattgcccat gtatggaaaa tctttttaca atctaatcat tttggtcgaa atttctatac
    65101 ggatgccgga ttggatgtcg aatcttttga acatgaaatt gatcgtctac tggatgagta
    65161 tccagttgtt tctggtggaa acgtccaata tggacaaaac ctcagccaga atttctttcg
    65221 attattgaat gaagcagacc aaatacgtga aagcttcggc gacgagtttc tttcaacgga
    65281 agtcgttatt ttagcgttga tgaaattaaa aaattatccg ttaactgttt atttgaataa
    65341 aaacggatta tctgaaaaag aattgcgtaa aaacatcgaa gagatgagag gaggagaaag
    65401 agtgacctca caaaaccaag aagaacaata caaagcatta gaaaaatacg gcgttgattt
    65461 agtacagcaa gtcaaaagcg gaaaaatgga tccaatcatc ggtcgtgatg aagaaatccg
    65521 tgatgtcatc cgtattcttt cacgaaaaac aaaaaataat cctgttctga taggagaacc
    65581 cggtgtaggg aaaacggcaa tcgttgaagg gcttgctcaa cgtatcgtac gcaaagatgt
    65641 gcctgaaaat ttaaaagata aaacgatttt ttcattagat atgggtgcat tgatcgctgg
    65701 agcaaaattc cgtggtgaat ttgaagaaag actaaaagca gtcttgaaag aagtcaaaaa
    65761 aagtgatgga cgtatcctct tgttcatcga tgaaatccac aatatcgtag gggcaggaaa
    65821 aacagaagga agtatggatg ccggaaatct gttgaaacca atgcttgctc gcggtgaatt
    65881 acatttgatc ggtgccacaa ctttagatga gtaccgtcaa tatatggaaa aagacaaagc
    65941 gttggaacgt cgctttcaaa aggtattagt caaagaacca acagtggaag atacgatcag
    66001 tattctgcgt ggattaaaag aacgttttga gatccaccat ggtgttaaca tccatgacaa
    66061 cgcattagta gcagcagcta ctttatctga ccgttatatt actgatcggt tcttaccgga
    66121 caaagcaatc gatttgatcg atgaagccag tgcaacgatt cgggtagaaa tgaactctat
    66181 gccaacggaa ttagatcaag ttactagacg tttgatgcag ttggaaatcg aagaagctgc
    66241 actgaaaaaa gaatcagatg atgcaagtaa aaaacgcttg aaaaatttgc aagaagaatt
    66301 agctgaactt cgtgaagaag caaatgcgat gaagatgcag tgggaaacag aaaaagaaga
    66361 agtcaattct gtttcagcaa aacgtgctga aatcgataaa gcaaaacacg aattagaaga
    66421 tgcagaaaat aactatgatt tagaacgcgc tgctgtattg cgtcatggta cgatacctca
    66481 attagaaaaa gaattgaagg aattagaagc taaagcaaaa gacagcgaga ttaagatggt
    66541 tcaagagtcc gttaccgaaa atgagattgc tcaagtcgtt ggcagattaa cgggtatccc
    66601 cgtaacgaaa cttgtagaag gtgaacgaga aaaactaatt aaattgaatg aaacacttca
    66661 taaacgagtg attggtcaag atgaagcagt tgatgcggtc agtgacgcgg taattcgttc
    66721 acgggctgga ttgcaagacc caaatcgtcc tctaggttct ttccttttcc taggaccaac
    66781 tggtgtcgga aaaaccgaat tagcgaaagc gttagctgag aacttgtttg actcagaaga
    66841 tcatatggta cggatcgata tgagtgaata tatggaaaaa catgctgtgt ctcgtctagt
    66901 cggagctcct ccaggctatg taggttacga agaaggtggt caattaacgg aagctgtcag
    66961 acgaaatcct tatacaatcg tcttgttgga tgaaatcgaa aaagcgcatc ccgatgtctt
    67021 caatatcttg ttacaagtcc tagatgacgg acgcttgact gattcaaaag ggcgagtagt
    67081 agatttcaaa aatacggttc tgatcatgac cagcaatatc ggttcacagt tactgctgga
    67141 aggcgtgact gctgatggaa cgattccaga agcagtggct gaacaagtca acacgctatt
    67201 acgtggaaac ttcaaaccag aattcttgaa ccgaatcgac gacacgattt tatttacacc
    67261 attgagccta gacaacgtga aaggaatcgt tgacaaaatg gtggcgcaat tggcacaacg
    67321 tctggaacat caagaaatcc tgctgacaat cagtgatgaa gccaaaacgt ggattgctga
    67381 aaatgcttat gaaccagcat atggtgcaag accattgaaa cgatttatca ctaaggaagt
    67441 agaaacacca ctagctaaag aaatcgttgc aggacatgtt atgcctaaat caaaagtaac
    67501 gattacttta cttgatggac aacttcattt caaaacagaa gagctagaag aaatcgtcta
    67561 atcttccatt gagactataa aagaaaaaag gggtctgaca caactagtgt cagacctcct
    67621 tttttcaaat aaacagtgtt ccagaagtag tttcttcgaa aaataagccg aaatttcttg
    67681 aagctgcccg cttctgtcac aacctctttt attaggtatt tttcactttt tctaatttat
    67741 aactttcaaa gtaacgctca tcttttttac tttgagacca tgcaaacaat cccattaagg
    67801 cagcacctat cgtatttgtc agcaagtcgc ccatcgtatc catcaatgct gctcgtccga
    67861 caaacagtgt gccatcagaa gcagcaaaac gttgaagatt catgcctaag aactggtcgc
    67921 ataagaattc ccagaactcc caaaacacgc cgcaaagtcc agcaaacgca aagccgaata
    67981 agaggaacaa ccaaggactg gtttttgata tctcagcatc tttcatcaag taaccaatca
    68041 atccatagcc aagagctgtc aggaccattg gactcaccgc atgtaagatt ttgtcccaaa
    68101 aagagatgat actgatcaaa tgcatccctg tgcctaaaaa gacagagatg aacaagaaaa
    68161 accagtaaaa caaaacgatt gctgctggta ttttaagttt gaaaactttc aaaatgactt
    68221 gtggcatgaa aatcaatgca atccctaata aagattccac gataaatgtg attccttgag
    68281 aagtcgaata tttttgtgtg ataaattcat aaaaattata gcagacaacg aatacaccaa
    68341 aagcaagtaa agctatttgc acctttttga tttctttaat cactgaaagt ccctccatct
    68401 aaaaatcttt ttacttctga aagcaactca atttctgaag aaaccacttt tccgttcaat
    68461 ttgatcaaac ctattgtata taagttcagg tagtgaaatt gattttcagc tgtttcttgt
    68521 agtgcagcga tttttttcgg gtgggttccg ccttgctgtc gagtatcagt atataagccg
    68581 atcactggga tgcctttcgc ataagccaca ccgatttccg atgctacccc ggcatcgatc
    68641 gtcagcccat ctagtaaagc aatcattaaa tcactagcca acactttttc tgtgtcagca
    68701 agagcaatca ttcgactgtc tgcataagca gttttgtcat tgattgcttc attttcttga
    68761 ggaagataga tcgaaagctc agaagagagc tctctgattt ctttaactaa ctgttggtta
    68821 tataacaaat cacttttagc aaacattggt gcggcaaaat aaattttcat ctaaacatca
    68881 tcctttttat caaaaataat cgctaaagta agcttccatg tttggaatga tacgctctag
    68941 tgacttcagt gtttcttcat ctgtttctaa ccgttcgatt cttgccaaat aagaagcacg
    69001 gcgataattc atcatcaagc aagtcaatgt ttggatatcc agtcgaacgg attttcctat
    69061 aggttcattt aagacacgga cttgtccctg ttcatcccat gttaaagcga agacaccatt
    69121 attccaagga gcgacaggat cttcaatgat gaaatgaaaa gcatcagctg ttccaacaaa
    69181 cggaaaccgt tgaaggaatt cttttacatc aacgatccga gccataaaat atggttcgat
    69241 ctgctctttg atctgactat cttcaatcaa aaatgctaaa ggctcatttt tataaatatc
    69301 tccatgtacc cagtagatca tggaaaaatg tgcggaaata aagttccata agccatttcg
    69361 agcttcttga tcaagataga acatttcttt tacgtgaaat atttcttcag ctacccagta
    69421 gaacagaaca cctcttggtt catggttgct atcgtagtag acagcggctg tgcgctcatc
    69481 ttcattttcg aaacgccaat actcttccca atgaaaatca ctgcggaata aagcaccatg
    69541 gttttgttgg gcaaatttgt cataaacgga aaatacgtct ggatgatcaa ctggtaatcg
    69601 ctcaaccata ccacttactg ggatttgttt aggtagctgt gtatctctga ttttaaagga
    69661 aagtttatca gacatgattt cccatccttt acgccgatag taggggatac tgtaaggata
    69721 caaataagag atccattgct tattcttgcg catattatcc aatgcaacga taattagatc
    69781 ttgcatcaat ccatggttag catattctgg ataagttcca actccagtca caccacccat
    69841 tttataacgt gcaccgtgaa tattgacttc acaaggatag atagcgattt gagagatcag
    69901 tttattttcg tggaaccatc cgaacacttt cgatacttcc aaaatcggtt ttttggaacg
    69961 gataaaagct cgtttattct caaacccgct ttcctcgatg tctgcttcag tcacttggaa
    70021 cacataggaa agcaattcat tgaattgatc gatatgttct tgagtgaccg gttttaattc
    70081 aagattttct ctaaaatctt tttgatccat tttttcatct ccatttatta gcttgataac
    70141 agtatagcaa aattctacaa aaaaaacttc tatagctgac taattaaaaa ctctttaaat
    70201 tactgctttt cgttggtata atggaaagtg ctgattatat gaaaagagga gacgctatgg
    70261 atataaagaa aatgaaagaa cgccaagagc agattcgtaa tttttcgatc atcgctcata
    70321 tcgaccatgg gaaatctaca ttggccgatc gtattttaga aatgacgcac actgtgacgt
    70381 ctcgcgaaat gcaagatcag ctgttagact cgatggattt ggaacgtgaa cgtggaatca
    70441 cgattaaatt aaatgctgta gaactcaatt acacagcgaa aaatggagaa acatatatct
    70501 ttcacttgat tgacacccca gggcacgtcg acttcaccta tgaagtctct cgaagccttg
    70561 ctgcctgtga gggtgccgtt ttagtggtcg atgcagcaca aggaatcgaa gcacaaacat
    70621 tggccaatgt ttatttagcg ttagacaatg atttggagat cctgccagtc atcaataaaa
    70681 tcgacctacc cgcagcagat cccgaacgtg tccgtcaaga aatcgaagac gtaatcggaa
    70741 tcgatgctag tgaagctgta ttagccagtg ccaaatcagg gattgggatt gaagatattc
    70801 tcgagcagat cgtggaatat gttcctgcac caagtggaga cttagatgca ccgctaaaag
    70861 ctttgatctt tgactctatt tatgatagtt accgcggtgt tgttctaaat gtccggatca
    70921 cggacggtat ggtcaaaccc ggagacaaaa tcaaactgat gagtaatggc aaaacatttg
    70981 atgttacaga ggtcggggtc ttctcgccaa aagcagttgc tagagacttt ttgatggtcg
    71041 gtgatgtcgg ttatatcaca gcaagtatca aaactgtcca agatacacga gtaggggata
    71101 cagtaacgtt agcagacaat cctgccgctg aagctttacc aggttaccga aaaatgaatc
    71161 cgatggttta ttgtggtctt tatccaattg atacttctcg ttacaacgat ttgcgggaag
    71221 ctttagaaaa actgcaattg aatgatgctg ctttacaatt cgaaccagaa acctctcaag
    71281 cattaggttt tgggttccgc tgtggattcc tcggacttct tcatatggat gtcgtccaag
    71341 aacgcttgga acgggaattc aatctagaat tgatcacgac tgcaccatcc gttatttacc
    71401 atgttaataa aacggatggt acgactgcta cagtagataa cccggcagat tttcctgaac
    71461 ctgtaacgat tcaggatgta gaagaaccat tcgtcaaagc acagatcatg gtcccaaatg
    71521 attttgtcgg tgcagtaatg gaactttctc aacgaaaacg gggagaattc attacgatgg
    71581 attatttaga tgattaccga gtaaatgtcg tctataatat tccgctttct gaaattgtct
    71641 ttgacttttt cgacaaattg aaatcaagca cgaaaggcta tgcctcattg gattatgaaa
    71701 tgtctggtta tcaaaaaagc aagttagtga agatggacat cttgctgaat ggagaaaaag
    71761 tcgatgcatt aagctttatc gttcaccgag actttgccta tgaacgtgga aaagcaatcg
    71821 ttgaaaaact gaaaaaacta atcccacgcc aacaatttga ggtgccaatc caagcagcta
    71881 ttggacaaaa aatcgttgcc cgttcagaca tcaaagcctt gcgtaaaaac gtcttggcta
    71941 aatgttatgg tggagatgtt tctcgtaaac gtaaactctt agagaaacaa aaagaaggga
    72001 agaagcggat gaaacaaatc ggctccgtcg aagttccgca agaagccttc atggccgttc
    72061 tgaaaatgga cgaggacgaa ccgaagaaat agcaagggtt tgtttgaaaa cagtgtaaaa
    72121 aataaaccat gtttacatgg atttgccacc ggtttgccac cggtggtttt tttcggtggc
    72181 aaaaatcaag aattctttct aagattttcc atgatatcga ccgtttcatt tctcatctta
    72241 tctgttacat gcgagtaagt atccatcgta attgaaattc tgctgtggcc caatcgttca
    72301 gagatttctt tcatttttgc gccattttcg agaagaagtg tagcatgagt atgtctgaga
    72361 gaatggaagt taaaagagag ggagagtgca ttcgatatcc tcctagtatt ccatttcact
    72421 acacttggcg taactagctc accgtcttcc ttcgtacata ctgtatttga atcaatgtag
    72481 agctttccat acttcattcg attttctaat tgttgtttct tatgtttttt cagaattgct
    72541 agcaaggttt gtccaataaa aatcgttcga ttggaactgc ttgtctttgg cgtaccatat
    72601 acccatgcgc cgtcattctt taccatttgt ttctctacag taattgttcc atttgaaaaa
    72661 tcgacatcat cccacgtcag accacaaact tcgccaacgc gcattcccgt ataaaatcca
    72721 atattcaaag gaatatagaa aggatgtcct tcaggagtaa tttctagcat atgatcaaag
    72781 tcctcaagag aaatgatttt tagatctttt ttagtcgttg gtcgtgcttc atattttggt
    72841 atttttacat acagcatagg attttgcttg attaatcccc aaggataaac cgccatattc
    72901 agcgcattct taaggacaga gtgagtaata gtcattgttt tcttcgagta acccttttta
    72961 aattcagcat tgatgaaatt ttgtaaaaga gcaggggaga gatccgtaag ttttttcttt
    73021 cctaaataac cgtttatatg atttttgatg gtaaatcggt agttttcata ggtattgtat
    73081 tttagattta gtttaacgta ttcctccatc caaaaatcaa ggtattgttt tactcgagta
    73141 tccgtaccta aaaagtattg tcctgtttcg tcaatatctg ataaaacttt tcgtaaagca
    73201 gcttcggcct ctggtcgggt gtctccgcca actttctcca ctttttttct tgagccatca
    73261 tcattgatat ct
//
LOCUS       DAIGWC010000004        65791 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.004, whole genome shotgun sequence.
ACCESSION   DAIGWC010000004 DAIGWC010000000
VERSION     DAIGWC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.004"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            476..1339
                     /locus_tag="NOB74_000266"
     CDS             476..1339
                     /locus_tag="NOB74_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI1219479.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="NOB74_000267"
     CDS             complement(1468..3090)
                     /locus_tag="NOB74_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1219480.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="NOB74_000268"
     CDS             3339..3860
                     /locus_tag="NOB74_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCI1219481.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="NOB74_000269"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="NOB74_000269"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HCI1219482.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="NOB74_000270"
     CDS             5941..6759
                     /locus_tag="NOB74_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HCI1219483.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="NOB74_000271"
     CDS             complement(6862..7059)
                     /locus_tag="NOB74_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219484.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="NOB74_000272"
     CDS             7228..7806
                     /locus_tag="NOB74_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCI1219485.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="NOB74_000273"
     CDS             7901..8038
                     /locus_tag="NOB74_000273"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219486.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8851..9354)
                     /locus_tag="NOB74_000274"
     CDS             complement(8851..9354)
                     /locus_tag="NOB74_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCI1219487.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="NOB74_000275"
     CDS             9713..10738
                     /locus_tag="NOB74_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI1219488.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="NOB74_000276"
     CDS             11061..11939
                     /locus_tag="NOB74_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HCI1219489.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="NOB74_000277"
     CDS             12415..12531
                     /locus_tag="NOB74_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCI1219490.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13459..13797
                     /locus_tag="NOB74_000278"
     CDS             13459..13797
                     /locus_tag="NOB74_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219491.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13891..14121
                     /locus_tag="NOB74_000279"
     CDS             13891..14121
                     /locus_tag="NOB74_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219492.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14521..14892
                     /locus_tag="NOB74_000280"
     CDS             14521..14892
                     /locus_tag="NOB74_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HCI1219493.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15166..15858)
                     /locus_tag="NOB74_000281"
     CDS             complement(15166..15858)
                     /locus_tag="NOB74_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI1219494.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15861..16646)
                     /locus_tag="NOB74_000282"
     CDS             complement(15861..16646)
                     /locus_tag="NOB74_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI1219495.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16883..18283
                     /gene="lacG"
                     /locus_tag="NOB74_000283"
     CDS             16883..18283
                     /gene="lacG"
                     /locus_tag="NOB74_000283"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCI1219496.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18308..18625
                     /locus_tag="NOB74_000284"
     CDS             18308..18625
                     /locus_tag="NOB74_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI1219497.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18638..20311
                     /locus_tag="NOB74_000285"
     CDS             18638..20311
                     /locus_tag="NOB74_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HCI1219498.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20325..21956
                     /locus_tag="NOB74_000286"
     CDS             20325..21956
                     /locus_tag="NOB74_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HCI1219499.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="NOB74_000287"
     CDS             complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="NOB74_000287"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCI1219500.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24071..24994)
                     /locus_tag="NOB74_000288"
     CDS             complement(24071..24994)
                     /locus_tag="NOB74_000288"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCI1219501.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25190..25795
                     /locus_tag="NOB74_000289"
     CDS             25190..25795
                     /locus_tag="NOB74_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1219502.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26103..27119
                     /locus_tag="NOB74_000290"
     CDS             26103..27119
                     /locus_tag="NOB74_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI1219503.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27260..28561
                     /locus_tag="NOB74_000291"
     CDS             27260..28561
                     /locus_tag="NOB74_000291"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCI1219504.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28607..29269
                     /gene="deoC"
                     /locus_tag="NOB74_000292"
     CDS             28607..29269
                     /gene="deoC"
                     /locus_tag="NOB74_000292"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCI1219505.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29290..29688
                     /locus_tag="NOB74_000293"
     CDS             29290..29688
                     /locus_tag="NOB74_000293"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCI1219506.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29754..30836
                     /locus_tag="NOB74_000294"
     CDS             29754..30836
                     /locus_tag="NOB74_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1219507.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31048..32610
                     /locus_tag="NOB74_000295"
     CDS             31048..32610
                     /locus_tag="NOB74_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1219508.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32603..33736
                     /locus_tag="NOB74_000296"
     CDS             32603..33736
                     /locus_tag="NOB74_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1219509.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33736..34692
                     /locus_tag="NOB74_000297"
     CDS             33736..34692
                     /locus_tag="NOB74_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1219510.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34791..35957
                     /gene="deoB"
                     /locus_tag="NOB74_000298"
     CDS             34791..35957
                     /gene="deoB"
                     /locus_tag="NOB74_000298"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCI1219511.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35981..36799
                     /locus_tag="NOB74_000299"
     CDS             35981..36799
                     /locus_tag="NOB74_000299"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI1219512.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36816..37523
                     /gene="deoD"
                     /locus_tag="NOB74_000300"
     CDS             36816..37523
                     /gene="deoD"
                     /locus_tag="NOB74_000300"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI1219513.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="NOB74_000301"
     CDS             complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="NOB74_000301"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCI1219514.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38679..39260)
                     /locus_tag="NOB74_000302"
     CDS             complement(38679..39260)
                     /locus_tag="NOB74_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1219515.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="NOB74_000303"
     CDS             complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="NOB74_000303"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HCI1219516.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40395..40808
                     /gene="rpsL"
                     /locus_tag="NOB74_000304"
     CDS             40395..40808
                     /gene="rpsL"
                     /locus_tag="NOB74_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HCI1219517.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40892..41362
                     /gene="rpsG"
                     /locus_tag="NOB74_000305"
     CDS             40892..41362
                     /gene="rpsG"
                     /locus_tag="NOB74_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HCI1219518.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41456..43543
                     /gene="fusA"
                     /locus_tag="NOB74_000306"
     CDS             41456..43543
                     /gene="fusA"
                     /locus_tag="NOB74_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI1219519.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43715..44902
                     /gene="tuf"
                     /locus_tag="NOB74_000307"
     CDS             43715..44902
                     /gene="tuf"
                     /locus_tag="NOB74_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCI1219520.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            45309..45617
                     /gene="rpsJ"
                     /locus_tag="NOB74_000308"
     CDS             45309..45617
                     /gene="rpsJ"
                     /locus_tag="NOB74_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HCI1219521.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45648..46277
                     /gene="rplC"
                     /locus_tag="NOB74_000309"
     CDS             45648..46277
                     /gene="rplC"
                     /locus_tag="NOB74_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HCI1219522.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            46305..46928
                     /gene="rplD"
                     /locus_tag="NOB74_000310"
     CDS             46305..46928
                     /gene="rplD"
                     /locus_tag="NOB74_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HCI1219523.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46928..47218
                     /gene="rplW"
                     /locus_tag="NOB74_000311"
     CDS             46928..47218
                     /gene="rplW"
                     /locus_tag="NOB74_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HCI1219524.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            47257..48090
                     /gene="rplB"
                     /locus_tag="NOB74_000312"
     CDS             47257..48090
                     /gene="rplB"
                     /locus_tag="NOB74_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HCI1219525.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            48133..48411
                     /gene="rpsS"
                     /locus_tag="NOB74_000313"
     CDS             48133..48411
                     /gene="rpsS"
                     /locus_tag="NOB74_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HCI1219526.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48434..48781
                     /gene="rplV"
                     /locus_tag="NOB74_000314"
     CDS             48434..48781
                     /gene="rplV"
                     /locus_tag="NOB74_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HCI1219527.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48795..49451
                     /gene="rpsC"
                     /locus_tag="NOB74_000315"
     CDS             48795..49451
                     /gene="rpsC"
                     /locus_tag="NOB74_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HCI1219528.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49454..49888
                     /gene="rplP"
                     /locus_tag="NOB74_000316"
     CDS             49454..49888
                     /gene="rplP"
                     /locus_tag="NOB74_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HCI1219529.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49878..50066
                     /gene="rpmC"
                     /locus_tag="NOB74_000317"
     CDS             49878..50066
                     /gene="rpmC"
                     /locus_tag="NOB74_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HCI1219530.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            50091..50357
                     /gene="rpsQ"
                     /locus_tag="NOB74_000318"
     CDS             50091..50357
                     /gene="rpsQ"
                     /locus_tag="NOB74_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HCI1219531.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50415..50783
                     /gene="rplN"
                     /locus_tag="NOB74_000319"
     CDS             50415..50783
                     /gene="rplN"
                     /locus_tag="NOB74_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HCI1219532.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50820..51128
                     /gene="rplX"
                     /locus_tag="NOB74_000320"
     CDS             50820..51128
                     /gene="rplX"
                     /locus_tag="NOB74_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HCI1219533.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            51156..51695
                     /gene="rplE"
                     /locus_tag="NOB74_000321"
     CDS             51156..51695
                     /gene="rplE"
                     /locus_tag="NOB74_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HCI1219534.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51714..51899
                     /locus_tag="NOB74_000322"
     CDS             51714..51899
                     /locus_tag="NOB74_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HCI1219535.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51935..52333
                     /gene="rpsH"
                     /locus_tag="NOB74_000323"
     CDS             51935..52333
                     /gene="rpsH"
                     /locus_tag="NOB74_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HCI1219536.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52365..52901
                     /gene="rplF"
                     /locus_tag="NOB74_000324"
     CDS             52365..52901
                     /gene="rplF"
                     /locus_tag="NOB74_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HCI1219537.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            53062..53418
                     /gene="rplR"
                     /locus_tag="NOB74_000325"
     CDS             53062..53418
                     /gene="rplR"
                     /locus_tag="NOB74_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HCI1219538.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53439..53939
                     /gene="rpsE"
                     /locus_tag="NOB74_000326"
     CDS             53439..53939
                     /gene="rpsE"
                     /locus_tag="NOB74_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HCI1219539.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53954..54133
                     /gene="rpmD"
                     /locus_tag="NOB74_000327"
     CDS             53954..54133
                     /gene="rpmD"
                     /locus_tag="NOB74_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HCI1219540.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            54177..54617
                     /gene="rplO"
                     /locus_tag="NOB74_000328"
     CDS             54177..54617
                     /gene="rplO"
                     /locus_tag="NOB74_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HCI1219541.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54617..55912
                     /gene="secY"
                     /locus_tag="NOB74_000329"
     CDS             54617..55912
                     /gene="secY"
                     /locus_tag="NOB74_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HCI1219542.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55974..56621
                     /locus_tag="NOB74_000330"
     CDS             55974..56621
                     /locus_tag="NOB74_000330"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HCI1219543.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56812..57030
                     /gene="infA"
                     /locus_tag="NOB74_000331"
     CDS             56812..57030
                     /gene="infA"
                     /locus_tag="NOB74_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HCI1219544.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            57063..57179
                     /gene="rpmJ"
                     /locus_tag="NOB74_000332"
     CDS             57063..57179
                     /gene="rpmJ"
                     /locus_tag="NOB74_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HCI1219545.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            57197..57562
                     /gene="rpsM"
                     /locus_tag="NOB74_000333"
     CDS             57197..57562
                     /gene="rpsM"
                     /locus_tag="NOB74_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HCI1219546.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57590..57979
                     /gene="rpsK"
                     /locus_tag="NOB74_000334"
     CDS             57590..57979
                     /gene="rpsK"
                     /locus_tag="NOB74_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HCI1219547.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58059..58997
                     /locus_tag="NOB74_000335"
     CDS             58059..58997
                     /locus_tag="NOB74_000335"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HCI1219548.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            59025..59405
                     /gene="rplQ"
                     /locus_tag="NOB74_000336"
     CDS             59025..59405
                     /gene="rplQ"
                     /locus_tag="NOB74_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HCI1219549.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59677..60516
                     /locus_tag="NOB74_000337"
     CDS             59677..60516
                     /locus_tag="NOB74_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI1219550.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60492..61361
                     /locus_tag="NOB74_000338"
     CDS             60492..61361
                     /locus_tag="NOB74_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI1219551.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61351..62148
                     /locus_tag="NOB74_000339"
     CDS             61351..62148
                     /locus_tag="NOB74_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCI1219552.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYCVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62351..63097
                     /gene="truA"
                     /locus_tag="NOB74_000340"
     CDS             62351..63097
                     /gene="truA"
                     /locus_tag="NOB74_000340"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCI1219553.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            63762..63999
                     /locus_tag="NOB74_000341"
                     /pseudo
     CDS             63762..63999
                     /locus_tag="NOB74_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(64143..64919)
                     /locus_tag="NOB74_000342"
     CDS             complement(64143..64919)
                     /locus_tag="NOB74_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI1219554.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            65042..65449
                     /locus_tag="NOB74_000343"
     CDS             65042..65449
                     /locus_tag="NOB74_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HCI1219555.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        20921 a        11725 c        13857 g        19288 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcat tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacat cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13441 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13501 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13561 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13621 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13681 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13741 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13801 ctagtgaaat actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa
    13861 tcgatcatca aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt
    13921 tattacgtga atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt
    13981 cgctactcaa ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa
    14041 actgtttttt ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat
    14101 tatgttagta tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt
    14161 tattgttttt tcgatatctt tgctgttaat attactaact ttaatgcagt ataaagagta
    14221 tccagagtat tttattttaa cttttgtata tttagtaagt agctacacac ttctatataa
    14281 attcagaagt tcttctagag tttctaaagt ttgtttctta attagcttat tgattctata
    14341 atatttttga tttatatagg aaattaaaaa tattatagaa tcaacactca gagaacgggt
    14401 tggtttttaa tagatttaat aagtactgat aatgaaattt ctcctggttg ggaaaacgaa
    14461 gttggttacc ctgtagaaga attttttcaa gattactttg cggagtatgc cgataggata
    14521 atgagagatt acgtaacaga taaaactcaa gaagtcatca atcaatccca gtcattaaat
    14581 gaattatctg ataaggcgaa agaagaagca gttgccatta tttcttcagg gattagtgac
    14641 tatattgata tgagtggtga aatcaattat ggcgataaag acaaaattgt acgcatgata
    14701 aaagctttta tcaaaacttt tgatgtgaag gcagatctta agtttaatga tacttaccta
    14761 gtaggaaaat taattaatat ccttgggaca gagaaagata cggaaacgtt tatttcctct
    14821 ttgtctatgt tgtttacaga taagcatttt tcaactcagc ttggtggaga ggaactagtg
    14881 gaaatctttt aaccattacg cccagcatta ataaaagtat atcaaaaaag tactcctgat
    14941 gatttttaag attggtttga gaaataatgt gaaaacacta tttttaatgt taattataga
    15001 tagagatgaa cgcgtcatat ggttaaaaga atgaaaaagt caaagataca ctgctatatt
    15061 tcactaagga tatagcagtg tatctttcat gtcgtttcac tggcagtttt ttataaaagg
    15121 aggtgtgcat ttcagttgct tttctttggt agttagttga atcgtttaag aattaacgga
    15181 tgtggcagac aggtgctctg tccaaaaacc agtaaaatct ttgatggttc catctttatt
    15241 tagctgtgcc tgttcaaata ctgttttgtt tttaccgaat ggatcaattg caataattgt
    15301 tccgatcccc gcacgtttgg cagcaagtaa tcctgagtaa gcatcttcga taacaagaca
    15361 atcagccgga gctaagctca gtttgtctgc cgctttaaga aaaatatccg gttgcggttt
    15421 cccagggaaa gagccgtcgt catagacaat cttgtcccag tcaaaccagc gggctaaatc
    15481 gaaaatatca aaataaaaag caacattctc tttgacagta gccgtggcaa tcgttaatgg
    15541 aatctgttgg tcagtcagct ggtcaagagt cgcttcaagc ccttttgtca actgaagctc
    15601 gttttcattt tgcaagcaaa gcatacgata atagctttct ttttcttctg acaatacggc
    15661 gatctcagag gcggtcaaat gctctgaaat gaaatgtttc aaaatctccg tattcgtccg
    15721 accatgaata ttttttaaaa tatcctcgtc tgataaacca tcttttgtat gatcatgtat
    15781 catatgcagc caagcagctt catgcagatg agagtccaaa aacattgttc cgttgaaatc
    15841 aaatataatc cctttcatag ttacgctcct atagtggtat tttcggttga atcagcaatt
    15901 tgcagatcga catattgtgc atagtgctct tgaacctccc gcgagatctg gcgatccgta
    15961 atgagcagat cgaaatcatg caaattataa aacacataaa aatcatctcg attgaatttt
    16021 ttattatcaa cgagtagata tttcttacgg gaattattta gagcgatctg ctgtgcttct
    16081 ccttcttcgg tactgtaagt agagatcgct tcgttgtgaa cgccatttga actgataaat
    16141 gcttttgtaa actttagtct tcttaaattg tcgttggtga tcggtccgac aaatgcgccg
    16201 gtatttttcc ggaaatcacc gccaatcagt agaatttctg gtccatctgc ttgagcaaga
    16261 atatcaaaaa ctggataatt atttgtaatg atccgaattt tcttgttcag taaatgcgtc
    16321 gccaatagtt cgattgttgt acctggtcct aagaaaatcg tttctccctc gtgaatcaag
    16381 gaggctgctg tggcagcaat ttcttttttt tcttgaatct gcagagtggc tttttcagtg
    16441 tgagaaagtt cttgatctaa agtgtaggaa agactttgag cccctccatg gacacgcagc
    16501 agcttgcccg atttttctaa ttcatctaaa tctctgcgaa cggtcatatc agaaacatct
    16561 aattgattga tgatttcatt aacggtaagg attccttttt tattgaccat ttctacgata
    16621 gtaagcaatc tttctttttt caacattgtc ttcacctcta atttaaggat aatctatcat
    16681 ataaacggac aacagtcaat ctaattcgaa caaaagtaaa catttagggt ggtttttatg
    16741 tttgttacaa tagattttat tgctgttttc tggtttttat gattatttgt gtttgttttt
    16801 gttgacaaat gttttggatg cgtttacaat gcaatcagtt agaaagagcg aaaactgatt
    16861 atagatttga ggagagatgt acatgcttaa attaccagaa gattttattt ttggcggagc
    16921 cacagcagcc tatcaggttg aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg
    16981 ggatgacttt ttagaggaac aagggcgatt cagtcccgat ccggcaagtg atttttatca
    17041 tcaatatgca aaggacattg aattgtgtga acgttttggt gtaaatggtc taagattatc
    17101 cattgcttgg agccgcattt ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc
    17161 tttttatcat cgtgtgttcg aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt
    17221 gcatcatttt gataccccta aacgtttgtt tgaccatgga gattttttga atcgagaaac
    17281 aatagaagca tttgtttcct atgccatttt ttgttttcat gaattcaaag aagtcaaggt
    17341 gtggagtacc tttaatgaaa tctatccagt tgcaaccaat caatatttgt taggtgtttt
    17401 cccaccagga atcaaatatg attttacaaa gatcgtcgcc tgtcttcata atatgatggt
    17461 tgctcatgcc cgtgtagtga actatttcaa agaaaacgaa cttccgggtg aaattggtgt
    17521 agttcactca ttagagacga aatatgcggc aacagacgcg ccggaagata agcatgctgc
    17581 ctttttagac gatgcattgt cgatccgttt cttattagat gctacctatt taggctatta
    17641 ttcaactgaa accttgactg ctcttgatga gatatgtgaa gcaaatcagg ccagctatca
    17701 ttttcctgaa gaagatttcg ttgaattgaa aaaagcatcc acgcgtaatg actacttagg
    17761 gatcaatcac taccaatgcc attttgtcaa agcttacgat ggagaaaatg caatccatca
    17821 taacggtacg ggtgaaaaag ggacctctgt ttataaagtg aagggaatcg gagaacgtat
    17881 ttataaagaa ggaattcctc gaactgattg ggactggctg atttatccag aaggtctata
    17941 tgacttgttg ctgcgaatta aaagcgatta cccacattac aacaaaatct atatcactga
    18001 gaacgggatg gggtataaag atcagtttga agatggcatt attatggatc agccgagaat
    18061 cgactatttg agagtctatt tggaatcctt aagcaaggcg ataacagccg gggtaaatgt
    18121 gaaggggtat tttttgtggt cgcttatgga tcttttctca tggacaaatg ggtataacaa
    18181 aaggtatggc ttgttttatg ttgattttga aacccagaag cgttacccaa aagaatcagc
    18241 ttactggtac aagttggtca gtgaaaccaa aacgattatt taataagtga taatggagga
    18301 agaaaagatg aataaagagg aattacaaat gcttggtttt gagatcgttg catattcagg
    18361 cgacgctcgc agtacattat tgaaattatt gaaagaagta agacaaggaa actttgaaca
    18421 tgttgattcg gcgttgaaag aagccgacga aaatttaacc cttgcacata attcgcaaac
    18481 aaaaatttta gcggaagaag catctgggaa agagatggag atgggattca tttttatcca
    18541 tgggcaggat catttaatga ccactttatt gctgagagat ctgattcaag actttattgt
    18601 actgtacaga cagaatcaag gataggagaa gaacgctatg gatggaatca ttaaacaaat
    18661 cgaaaaaggg aaaccatttt ttgaaaaaat ctcacgtaat agttatttag gagccgttcg
    18721 tgacggattt ttaacagcga tgccagctat tttattttca agcattttca ttttgattgc
    18781 tgcggttcct gagatttttg gttaccaatg gcctgaatct gtctccacat ggctatggaa
    18841 agtctataat tattcgatgg gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg
    18901 cttggctgat tcgatgaatc gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt
    18961 gatgctggcc tctgtggtaa gtttcctgtt gttaagcgtc tctccgattg aaggtggatt
    19021 ttcaacggaa tatatgggga caaagggact actggcttcc tttgtcgctg catttttaac
    19081 agttaattta tataagtttt gtgtgctgaa agatattacc attaaaatgc ctaaagaagt
    19141 tcctggaacg atttcgcaaa ccttccgaga tatttttcct ttctcttttt cagtatttgc
    19201 ggccgtttta attgatttag gcattcgaca aatcttccaa atctcatttg cagaagcaat
    19261 cattacggtg ctgcagccgc tatttacagc agctgacggg tacttaggaa tcgctattat
    19321 ctggggagcg atggcgctgt tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc
    19381 ggcaattgcg gcaattatct atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg
    19441 tgaacaagct tctaaagtac tgacggtggg tttagggaat tttgtaggaa ctatgggagg
    19501 aactggggca acattggttg ttccttttat cttcctactc tttgctaagt ctaagcagtt
    19561 gaaggcagtt gggaaagctt cctttattcc agtaagtttc gctgtcaacg aaccattgct
    19621 atttgcggca cccatgattt tgaaccctta tttttttatt ccatttttgt taacacctgt
    19681 tgtaaacgtt tgcctgttca agttttttgt cgatgtattg ggcatgaaca gctttatgta
    19741 cgttttgcct tgggcaactc cagcaccgat cggtttggtt ctaggaacgg gcatgggtat
    19801 cttagctttt gttctagcag cggttctaat cgtcgttgac ttcctgatct atctaccatt
    19861 ttgcaaagca tacgatgctg tcttagtaga gaaagaagca caaaaagcag aggtgatcgc
    19921 aaccgaggaa ggtgcttctg ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt
    19981 tatcagcgat gcaaataaag aaatcaatgt gttggtactt tgtgctggcg cagggacaag
    20041 tgcgatgtta gctaatgctt taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc
    20101 aatggcgggt gcttatggtt ctcattacga aatgctgcag gattttgata tggtggtctt
    20161 agcaccgcaa gtcaattctt actatgatga tatcaaagaa gacaccgatc gcttaggaat
    20221 caagctggtt gcgacaaaag gagcagaata tatcggatta acgagagatc ctgaaaaagc
    20281 tgttcagttt attctgaacc aatttcaata aaggaggagc cataatgaaa atgggaattt
    20341 ggttgcgtaa agctgtttta tttgcagctg tgttaggggc tttgggggct gtttcaaaaa
    20401 ctgttgaagc atctgccagc gaatttattc gcggagcaga tatttcgatc ctgtcagata
    20461 tggaaaaatc tggtgcaaaa tattatgaag acgatatttc aaaagatgcc ttagagattt
    20521 taaaaaataa tggtgtcaac tatgttcgac tgcgtttgtg gcaggatcct tataatagta
    20581 atggagaaag ttatggagca gggacaaatg atctggaaac gacgattgac cttgcaaaac
    20641 gagcaaaaaa tctgggactt aaggtgctgc tggattttca ctacagtgat ttttgggttg
    20701 atcctgggaa acagaatctt cctaaagcat ggcaaggtct gacctttgaa gaaatgaata
    20761 cggcattgta cgactataca aagaacgttc tgtcggaaat gaagcagctg gacgtttatc
    20821 ctgatatggt tcagatcggc aatgaactga atagcggaat gctctggcct tatggcaagt
    20881 cttggggaga aggcggggga gaatttgatc gattggctgc ttttttgaag tctggtatcc
    20941 aagctgttcg agacactcaa cctaaaacaa ctccagtaat gctccactta gctgatggtg
    21001 gcgatacagg agcatttact tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg
    21061 atttaattgg agtgtcgtat tatccgtatt ggcacggttc aatgaatgaa cttcaaacca
    21121 atatgaatgc gatcagccaa cggtatggta aagaagtgat cgtagttgaa acagcttatg
    21181 ggcatacaac agcgaatgcc gatactatgc caaatgcttt tggtgaagcc gaagcagctg
    21241 cggggggata tgaaccaaca ccgacaggac aagcagagta tttgctggat cttgccgatc
    21301 ggattcaggc agtaccgaat aatcgcgggg cgggcttctt ctattgggaa cctctttggt
    21361 acaacggaaa tgtgagttgg gcaacacaag caggtatgaa ttatctcagt gttcaatcca
    21421 ctatgggaaa cgaatgggac aaccaagcga tgtttgattt tgctggaaac gccttgccaa
    21481 gcttgcgtgc gtttaaacaa gcaggggcgc aaataaatct agttaaaaat gcaagtttcg
    21541 aaagcgatgg accaacgacc agtccttcca attggcaaac ctggtttcaa caaggaaccg
    21601 ctaagggtac gatcaaaacg gaagcgggca ctttttttgg ggactacaaa ctaacttttt
    21661 ggcaggatca agcatacgag gcatcagctt atcaaaatgt tagtggcata agcaaaggaa
    21721 cttacacatt gagtgcctat gtaatgtctg ggggagagtt tgatactaat cagttatata
    21781 tcaaaaatta tggtggagcg gaactaaata ctgcggttgt taaaacaagt gaatggacaa
    21841 aaattacaat caaagacatt ccaattacaa caggtgtttg tgaaattggg gtttatagca
    21901 aggcttcagg aaatgcttgg acgaacgttg attttgtttc attggtgaaa caatagactg
    21961 cggatcgttt cgattcaaga tcggaggttc ccttcagcca catcgttagc gtagaaggca
    22021 ggaatcgaac ctgcacctcg cctttgccaa aaataaccag aaacgatttc cagtcatttt
    22081 taccaaaacg agtaaagcac cagacttcat ctacactttg tattatgcta aagagagttc
    22141 aacgatttcg taagaagcaa tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt
    22201 gtttaagaaa gggtaacctt agaattccgt cgtgaatatg atttgagcac ttagatggat
    22261 agaaaaaagt tctcggaaaa cagttcgttt ttcgagaact tctttttatg ataagaatga
    22321 aacaaattaa cttatattat agtctctttt ggtagggaac catcttattt ttaatgaaaa
    22381 tcaagcattt tagctattga agaatgttga tttataggga ttccccctcc atattatgtt
    22441 ggctctttat tcccactcca ctgttgctgg tggtttagaa gtgatgtcat acacgatacg
    22501 gttgacgtgg gctacttcgt ttacgatacg tacagagatt ttttgcaaga cttcccatgg
    22561 gatacgggca aagtcagcgg tcattccgtc gattgaagtt acagcacgga taccgactgt
    22621 gtagtcgtaa gtacgtccgt cacccataac accgacagag cggatccctg gaagaacagt
    22681 gaaatattgc cagatatcac ggtcaagtcc agcagctgcg atttcttcac gcaagatagc
    22741 atcagattcg cgtacgattt ctagcttgtc ttcagtgatt tcgccaagaa cacgaatacc
    22801 aagaccagga ccagggaatg gctgacgcca aacgattgaa tcaggcatgc ctaactgagt
    22861 ccctaattca cggacttcgt ctttgaataa tgtgtttaat ggttcgatca attcaaattg
    22921 catatcttct ggcagtccac ctacattatg gtgagatttg atcgtctgtg ctgtttctgt
    22981 accagattcg ataacgtcag tatacaacgt tccttgtgct aggaaagaga cgccttcttc
    23041 accagcaagt tttgttgctt cgtcatcaaa aacatatacg aattcattcc caatgatttt
    23101 acgtttttgt tctgggtcag atacaccttt caacttgtct aagaagcgat ctcttgcatt
    23161 gactttgatg atgttcaagc cgaattttcc gcctagactt tccattactt gttccgcttc
    23221 gcctttgcgt agcagaccgt ggtcaacaaa gatagatgtc aattggtcac cgatcgcttt
    23281 ttgtaaaaga accccaacga cactagaatc aacgccacct gaaagaccaa gcaagacttt
    23341 tttgtcacca acttgttcac ggattttttc tacttgcata tcgataaagt tatccattgt
    23401 ccagttacct tcacagtgac aaacatcaaa ggcaaagtgg cgcagcaatt cgattccgta
    23461 ttcggaatga cgtacttctg catggaattg gataccataa aaattacgtg ttgtgtcttg
    23521 gatagaagca atcggacaat ctttgcttgt tccgactgtt tcaaagcctt caggaacttt
    23581 agttaccaag tcaccatggc tcatccatac tgtttgttgt tttggtgttt ctttaaacaa
    23641 gacagcttga tcgcttgtta cttctaacaa ggctttccca tattcgcggt ttttagcagg
    23701 ctctacggaa ccgccaagtt tgtacgtgat caattgcata ccatagcaaa tccctaatac
    23761 aggaatacct aaattgaaga tctcaggatc gatcccaaat gcattctcat catatacact
    23821 gtttggtccg ccagaaagaa tgattccctt tggattcatc gcttttactt cttctgcagt
    23881 aatgcggtgg ctcaataatt cggaaaagac tccaagatca cgaatacgtc ttgtgatcaa
    23941 ttggttatac tgactaccgt agtctaatac gataatcttt tcaacgttcg tcatatcggc
    24001 aacgtttgtc aaatttatta cccctatccc tttaaatttt atctcaaaat agtcaaacta
    24061 ttttaaaatg ctaatatttt cgcatgaaaa tcgaatcgat gatatgattt tcagttttat
    24121 ggagaattat atcggctctt cctcgtgtag gcaagatata ttcctgtaaa tttttcaaat
    24181 tcacattttt ccatacatct tttgccattt taaaggcttc ttcacgatct ccgatagcaa
    24241 aacgataata ataattctct ggattttgga aagccgtatc cagtaacgca ccaaaacgat
    24301 ccaaatacca tttttcgatc agcacgggat cggcatcgac atagacagaa aaatcaaaaa
    24361 agtcgctgac gtagatttgc tgattcgcag gtaattgaag cgtattgatc ccctcaacga
    24421 tcaagatatc aggctgctgg atcaattcgt acttgtctgg aatgatatca tacacatcat
    24481 gtgagtaaac aggtactttt atctcttcct gaccagattt tacacggttc aagaaatcga
    24541 tcagcatctc catatcataa ctttcaggaa atcctttacg gtccatgatt ccacgctctt
    24601 ttaatatacg atttggataa agaaatccgt cagtcgtgat cagctgaacg tttcttcgtt
    24661 tgaaggtacg agacaaaatc gtctgcagca gtctggctgt tgtacttttt ccaacggcta
    24721 cacttccggc gatcccgata ataaaaggcg gtacttctac gtatttatga agaaataaac
    24781 ctttactcaa gaacaaagat tcaaattctt tcatataaag ataaatcaga tgagcaagag
    24841 gtacatagat atctcgaaca tcctgcatgg aaatgcggtc attcaaactt ttgatattat
    24901 ctagttcatc ttgtgtcaaa ggtgcttgcc cattacgata aaattctcgc cattcttctc
    24961 ttgccacacg gtagtagttc attggatcat tcatattagc ctcctgcgtt ctcccatcaa
    25021 tggaactatt ttaacacaaa ataaacgcaa accccaccac ttaagagaga ttgccgatct
    25081 ttttgtataa tctttataat agaaagaaac ggagtcttat tcttgacttg cgcacggata
    25141 cataaaagga tagactgttg tcatgaaaga aatgagaagg atggaagaca tgacaaatca
    25201 ttactattct gaacgcccag atacggcgca cgattttgaa caatgggctt ttgagttaaa
    25261 aggcagaacc tttcaatttg taacagattc tggtgtattt tcacgtgaaa cagtggatta
    25321 tggttcacgt gtcctgattg atgctttcga ttgggaagag ttacctgatg aaggaaagat
    25381 cttagatgtg ggatgcgggt atggaccgat tgggttagct ttggcatttg cgacacagcg
    25441 gtttgttgaa atggtcgaca ttaatgaacg agcggtaagt ctagcgcaag gaaacgcaaa
    25501 gcgtaaccaa atcgaacatg ttgatatcca tcaatcgaat atctatgaag cagttcatga
    25561 agaaacctat gcagctatcg taagcaatcc gccgatccgt gctggaaaaa aagttgtaca
    25621 tgaaattttg acaggcgcat atcctcggtt gaagaagggc ggtacactga caattgtgat
    25681 ccagaagaaa caaggagcgc cgagtgcgca aaagaaaatg gaagaaacat ttggtaatgc
    25741 agaaatcgtc acaaaagata aaggatatta tatcatcaaa agtgtgaaag aataactagc
    25801 tgaaaaatag tggagcgacg aaagagtgga actgggcgtg catgtacggg tacgtatcag
    25861 ttcttttttt gttgagaagt ttttaaaaac aaagaactat tttttcttca aaaagaaata
    25921 gtaggaacag agtcgttgtt ttttacgata aaataaataa gatacagaac ttgtatagaa
    25981 ggctgccaag tcggtagata aaggaggttt ttatcaaaaa acatactttc cttttttctc
    26041 tattcttttc ttgggggttt tggtacactg atagggaatt tagatagaag ggagccaata
    26101 ggatgaagct gaccatcaga gatatcgcag aaatggcagg cgtatcagta acaactgtct
    26161 cacagatttt gaataacaaa ggaagcagat ttagtgataa gacaagaaaa aaagtgttgt
    26221 cgatcgtgaa tgaacatcat tataagcccg attatttcgc ttcaaatgtg atcaatcgac
    26281 attcaaagac catcggaatg atcgtccctg atgtcactga tttcttcttc tccaaactga
    26341 tcgaaggtgt agagagctat ttgaatcctt tgggctatgt gatcatgtta tgcaattctc
    26401 gtcatagcca agaaaatgag atcaagtatt tacaagagct ttcccaccgc tcagtggacg
    26461 gaatcttgct ggccacacca aatattttac ctgagaaata tgcattagac agcggttttt
    26521 atcaaaaaat gccaatcatt ttaatcgatc gcggattgaa tcgtcgggat aacggacggc
    26581 ttatcgtaaa ggaatatgag ggcgcctatc aagctgtttc gctgtttatt gaaaatggcc
    26641 atacgaagat cggcatgctg aaggaaacca ctggatacta tcaattagaa gaacgtttca
    26701 acggatatcg tcatgcgctg aaagatcatg gcctgccttt taatgggaaa tttgttgaac
    26761 atggagagtt gactgtccaa ggtggatata ctgcatcaaa aaaattactc aaacataaag
    26821 atatcacggc tattttttgc gggaatgatg ccatggcgat cggatgctat caggcgatcg
    26881 atgaattggg caaaaaaatc ccagaagata tctcagtcat aggattcgat ggattaaagc
    26941 tgtcagaata catgattccg caattgacga cagtgcagca gccaagtttt gatattggat
    27001 tttatgctgc acgtttcctg atcgatacga tcgaatttcc tcaaagaaaa gttccgaaca
    27061 aagtgttcga aacaaaatta attattcgtg agagcgtaaa agtattgaca aagggctaac
    27121 tcggcggtat attgcttatg taagcattta caaaggctag ttagtgcttt ttttattttt
    27181 agtaaaccag tttactaaag tggtttacct ttcctaaaaa taatgtataa taccgaatga
    27241 agacaaggag gatcaggcaa tgcgaatggt ggatctgatt gaaaaaaaga gggatggaaa
    27301 cgagctgtcg aaagaggaaa tcgagtacat cgtcacgaac tatacgaatg gaaagattcc
    27361 agattatcaa gtcagtgcat tattgatggc aattttttat caagacatga caaatgaaga
    27421 aatcacgaac ttaacattgg cgattgctaa ttctggtgat gtcatcgatt tgagttctct
    27481 tgaaggaata aaggtagata agcattcgac aggtggcgtt ggtgacacga ccacattgat
    27541 tttagccccc ctagtagcta gtgtcggagt gacagtggct aaaatgtctg gacgcggtct
    27601 aggttacaca ggtggtacac tagacaagct agaagcaatt cccggatttc agatcgagct
    27661 ttcggatgaa gaatttgtac gcattgttaa tgaaagtaaa gtagcggtaa ttggtcaatc
    27721 aggaaacttg gcaccggcgg acaaaaaatt gtatgccttg cgtgacgtca cagcgaccgt
    27781 tgattctctt ccgctgattg ccagttcgat tatgagtaaa aaaatcgcgg caggagcaga
    27841 tgcaatcgtt ttggatgtga ccactggaga cggtgctttc atgaagaaca tcgaagatgc
    27901 aagacgtctg gcaaagacca tgacgagcat tgggaaactg gctaaccgag aaacagtggc
    27961 ggttatctca gatatgtcag aacctcttgg cgaagctatc ggaaatagtc tagaagttgt
    28021 cgaggcaatc gaaacattac aaggaaatgg tccagaagat ctagtagaaa tgtgctacgc
    28081 cttaggaagc caaatggttg ttcttgctgg caaagctaag acaaccgatg aagcaagaac
    28141 gttgcttcaa gaagctctgg aatcaggtaa agcgttagca aaattcaaag aaatgatcca
    28201 aaatcaaggg ggagacccag cgatcgtgga acatccagaa cgaattttga ctgcacgcta
    28261 cacaatggag cttcctgcta aacaaagcgg agttgtgtca aaaatcgtgg caaatgaatt
    28321 aggaattgct gcaatgatgc taggtgctgg gcgtaaaacc aaagaagaag atattgatca
    28381 cgctgttgga ttgaaactgc ataaaaaaat tggtgacact gtgacaaaag gtgagtcact
    28441 attgacgatc tatagtaacg acgaagaaat cacttctgtc attgaattat tatataaaaa
    28501 tattgaaatt ggtgaatcgg caatgaagcc aacgttgatt catgacatca tcacagaata
    28561 aaggaaaaaa gcggacttta ccgttttaaa gaaaagggga aaagaaatgg aactaaaccg
    28621 aatgatcgac catactattt tgaaagcaga cgcatctaaa gaagctgtga tgcaaattat
    28681 cgaagaagca aaaaaatacc atttttattc tgtctgcatc aatccagcat gggttgcgct
    28741 agcgaaagaa caattacaag gtgagccagt agccgtatgt acagtaatcg ggtttcctct
    28801 aggagcaaac acacccgaga caaaagcatt tgaaacaaca gatgccatca ataacggtgc
    28861 agatgaagtc gatatggtca tcaatatcgg tgctttgaaa tcaaaggatg atcaacaagt
    28921 ccaaaaagat atcgaagcag ttgttgaagc agcaaaagat cgtgcgcttg tcaaagttat
    28981 tattgaaaca tcgttattag atagagaaga aatcatccga gcttgcgaaa tagcaaaagc
    29041 tgcaggcgct gattttgtca aaacatcaac tggtttctca acaggcggag caaaggtaga
    29101 ggatgtccgt ttgatgcgtg aaactgtagg accagaaatg ggtgtcaaag cttccggcgg
    29161 tatccataac gaagaagaag caatggcaat gatcgaagct ggtgctacaa gaatcggaac
    29221 aagcgcagga gtagcaatcg tatctggttc aactggtgaa ggctattaat tttttcaaag
    29281 gagaagctca tggcagaact caaacaagaa tggatcaaca cagctattga agcgttagat
    29341 aaagcctatg ttccttattc ccattttccg gtaggcgctt gtctcgtaac ggaatcaggc
    29401 aagatttatc aaggcatcaa cattgagaat gcatcatttg gattaacgaa ttgtgccgag
    29461 cgcacagctt ttttcaaagc agtatctgaa ggagaaaaaa catttacgca tctagtcgta
    29521 gcggggcaca cccccgatcc tatctctcct tgtggtgcat gtcgacaagt aatggcagaa
    29581 ttctgttccc ctgatatgcc ggttacgcta gtaggagaca atggtgtgac gaaggcaacg
    29641 accgttcgtg cactgctgcc ttatgcattt actgaaaaag atctataact catgttcatt
    29701 cagtcagctg actgttgaaa aataaaacaa ttattttagg aggctttaca gaaatgaaaa
    29761 aagcaaaatt atttggttta ggtgctgtcg cactagcagc agggttattt ttaggtgcat
    29821 gcggcaacaa cggctctact gattcatccg gtggcaaaag ctcatcagac acaacaactg
    29881 cagcattgat cacagacaca ggtggtgtag acgaccgttc attcaaccag tcagcttggg
    29941 aaggactaga aaaatggggg aaagatcaag gactttcacg aggaaatgat ggcttccaat
    30001 atttccaatc ttcaaatgaa tcagattaca tcccaaatat tgaccaagca ttgaatgctg
    30061 gattcaaaac gatttttggt attggttata aactaaaacc agcgatccaa gaacaagcaa
    30121 caaacaatac aggtacgaac tttgttatta tcgatgatgt catcgatgga ttagataacg
    30181 ttgtatctgc aactttcaaa gacaacgaag cttcttatct tgcaggtgtt gcagcagctt
    30241 atacgactga aacaaacgta gtcggcttta tcggcggtgt aaaaggtgaa gtaatcgatc
    30301 gttttgatgc tggattcaaa gccggtgttg atgcaggtgc gaaagaatta ggaaaagaaa
    30361 tcaaagtatt gaatcaatat gctggtgact tctctgctcc agataaagga cgttcaattg
    30421 ctcaaggtat gtatgcacaa aacgcagata tcatcttcca tgcttcaggc ggtacaggta
    30481 acggtgtatt ccaagaagca aaatcattga acgaatcagg cgacaaaaaa gtttgggtta
    30541 tcggtgttga ccgcgaccaa tcagacgaag gcgaatacac attaaacggc gaaaagaaaa
    30601 acttcacatt gacatctaca ctgaaagcag ttggaacagt agtagaagat ttggcacaaa
    30661 aatcagcgga cggtaaattc cctggcggcg aacacactgt ttatggattg aaagaagacg
    30721 gtgttggtct aacagaagga caactttctg acgaagcgaa aaaagcagtt gatgaagcaa
    30781 aagaaaaaat catttcaggt gacgtaaaag ttccagaaac tcctgaagaa aactaaaacc
    30841 atttctatag ccttgttaga cacatgtttg acaaggctat ggtttgatta gaacaagaat
    30901 tgttcattta tccaagctgc cttgtgacag tttggataag ggaacaactc cctgaagtaa
    30961 tgtttgtttc aaaagaagaa cgctcactaa gcgtgaatct tagtcaatcg ttgccctaga
    31021 tagaaatcgt taggatgtga aaaaaaggtg gttcaagaaa atattgtcat agaaatgcag
    31081 aatattacca aagaatttgg aacattcaag gcaaatgaca acatcaattt acaagtaaag
    31141 gcaggagaaa ttcatgcgtt gcttggagaa aacggtgctg gcaaatctac attgatgaac
    31201 gtgctttccg gattattaga gccgacatca gggaaaattt tgatgcgtgg gaaagaagta
    31261 aagatcacaa gtccgaccaa agccaaccaa ttagggattg ggatggtcca tcagcacttt
    31321 atgcttgttg atgcctttac tgtaacagaa aacatcgtgt tgggaagcga gcctagtcgc
    31381 gcagggatgc ttgaccataa aaaagcacga aaagagatcc aaaaagtttc tgaacagtat
    31441 ggattgtcag tcaacccaga tgcttacgtt cgtgatattt cagttggaat ggaacaacgg
    31501 gtagaaattt taaaaacact ttaccgagga gcagatgtac tgatttttga tgagccgaca
    31561 gctgtattga cccctcaaga aattgatgaa ttaatcgtga tcatgaagga attagtcaaa
    31621 gaaggcaagt cgatcatttt gattacgcat aagttagatg aaatcaaagc agtagctgac
    31681 cgctgtacag ttatccgccg tggaaaagga atcggtacag tcaacgttaa agacgtaacc
    31741 tcacaacaat tagccgatat gatggttgga agaacggttt cattcaaaac gatgaaaaaa
    31801 gaagcgaagc ctcaagaagt cgttttgtct attgaaaatc tagtggtgaa agaaaatcgt
    31861 ggattagaag ccgtgaaaaa cttgaactta gaggttcgtg ctggcgaagt acttggtatc
    31921 gctggaatcg atggaaacgg gcagtcggag ttgatccaag ctttgactgg tttgcgaaag
    31981 gcagaaagcg gacatatcaa gctaaaaggg gaagacatca ctaataaaaa accccgaaaa
    32041 atcactgaac atggtgtagg acacgtgcca gaagaccgtc ataaatacgg gttagtccta
    32101 gatatgacat tatctgaaaa tatcgcacta caaacctatc atcaaaaacc ttacagtaaa
    32161 aacggcatgc tgaattattc agtaatgaat gaacatgcca gagaattgat cgaagaatat
    32221 gatgttcgaa caacgaatga acttgttccc gcaaaagctt tatcaggcgg aaatcagcaa
    32281 aaagcaatta tcgctcgtga agtcgaccga gatcctgatc tgttgattgt tgcaaatcca
    32341 actcgtggac tggatgtagg tgcgatcgaa tttattcata aacgtctgat cgaacaaagg
    32401 gacaaataca aagcagtgtt actgatcagt ttcgaattag aagaaatttt aaatgtttcg
    32461 gatcgtattg ctgttatcca tgaaggagaa attgtcggta tcgttgatcc gaaagaaaca
    32521 tctgaaaatg aattaggtct attgatggcg ggctatacct tagaagaagc acgaaaagag
    32581 ttagaaaagg gggctggcgc acatgaatga tcgcagcgaa aaattccgta atttattagt
    32641 gcctgtactt tcagttgttt taggattgat cttaggcgcg atattgatgg ctgcttttgg
    32701 ttttcagccc atccaaggtt attcttctat gctagatgca gcccttggtt cgcaaagagg
    32761 gataggtgaa acgttaaggc aagcaacgcc gttgattttt acagcattag gtttttctgt
    32821 agctaactca gctgggtttt tcaatattgg gctttctgga caagcacttt gcgggtggat
    32881 cgtcagtgtc tgggtggcac ttgcgtttcc agatctgcca aaagttgttt tgcttccgtt
    32941 atgcgtgatc ttaggtgcct tagctggtgc gatggcagcg gctgttccag gtttacttcg
    33001 agcatttttt ggaacaagtg aagtgatcgt aacaatcatg atgaactata tcttattata
    33061 cgtaagcaca tttgctttac atgaagtgat gcctgaaagc tatcgctcaa gtttggactc
    33121 ttccaatatg atcagtcaaa atgcctcact gcggttacca tggttaacac aagcttttgg
    33181 cggctctcgc gtaaactcag gattattttt agcaatcatc gcgcttattt tcgtttggct
    33241 gctgatgaag aaaacgactt taggatttga aatccgttct gttggattga atccttttgc
    33301 ttctgagtat gcaggaatga gtagtaaacg tacgatcgtt ttgtcgatgg tcatttctgg
    33361 cgctttggca gggcttggcg gtgtggttga aggattagga acgtatcaaa acttctttgt
    33421 tcaaacgact tcgctatcta ttggatttga cggaatggct gtttccttgc ttggttctgg
    33481 atcagcaatc ggtattcttt tatcagcgat cttgttcagt attttgaaga tcggtggact
    33541 tggcatgcag acaggagcag gtgttccgtt tgagatcgtc aatgtatcga ttgctttgat
    33601 tatcttcttt gtcgggatca acttcctgat tcgtttcgtc atggctaaag tcttccaagg
    33661 gaaaaaacaa gaagagatcg ttgcgacaat agaatcgaaa ccaacgaatc aaaaccatga
    33721 agggggcgaa ctataatgtc gactatcgaa ttaattgcct tgatccttac ttctacactg
    33781 gtttattcaa caccgctaat tctaacgtca ctaggcggaa ctttttctga acgaagcggg
    33841 atcgtaaacg tagggctaga gggaatcatg gtcatgggtg cttttagttc catcgttttc
    33901 aacttgacga tgagtccatc acttggttct atgacaccat ggatcgctat tttagtgggt
    33961 ggcgtcgtag gtatcctatt ttctctgatt cacgcagtag caacagtcag tttgcgtgct
    34021 gaccatatta tcagcgggac agtaattaat ctgatggcac ctgctttagg tgttttcttg
    34081 atcaaagcat ggtatggtaa aggtcaaact gataacatca cgcagaatct ggggtatttt
    34141 tctttcccag gattagcaga tattccggtc attggaccaa ttttctttaa aaatacattc
    34201 ttacctgctt attgtgctat tttgattgct gtcctagctt gggtgatcat cttcaagacg
    34261 aaattcggct tgcgcctccg ttcagttggt gaaaatcctc aagctgccga cacattaggt
    34321 atcaatgtat atgctatgcg ttattcaggc gtactgattt ctggcttgtt aggcggtatg
    34381 ggcggtgctg tttttgctca gtcgatttcc ggtaactttt cagctggtac gatcgttgga
    34441 caagggttca tctccatggc tgctatgatc tttggtaagt ggaatccttt aggggcaatg
    34501 ggtgcctcat tgttctttgg ttttgctcaa agcttgagta tcattggcgc acaattacca
    34561 gttatttctt cgattccgcc agtattgctg caaattgctc catatttgct gacaatcatt
    34621 gtgctggttg ttttcttagg gaaagcttct ggtccaaaag caaacgggaa gaactatatc
    34681 aaatcaaaat aatcttttag cgaataaaaa gggtgggtta cgggaagtgt ttttcgtctc
    34741 gccctttttg ttttaaaggc aataaaaata aaaagaaaga aggaataatc atgtttaaac
    34801 gcgtacatct gatcgtcatg gattcagtag gaattggaga agcaccagat gccgataagt
    34861 tcggtgatgt tggttctgat acattaggac acattgcgaa agaagcagga ttgaacgttc
    34921 cacatttaga gcagcttggt ttaggaacga tccgtcctct tgaaggtgtg gaatcagtga
    34981 aagatcatca aggctatgcg acgaaattag aagaagtttc tgtagggaaa gatacgatga
    35041 caggccactg ggaaatcatg ggattgaata tcaaaactcc atttcgtgtg tttcctaatg
    35101 gattccctga tgatctgatc aaacaaatcg aagaattttc tggccgtaaa gtcgtatgta
    35161 acaaacctta tagcggaaca gctgttattg acgattacgg tgaacaccaa atgaaaacag
    35221 gcgatttaat tgtatatact tctgccgatc ctgtccttca gatcgcggca catgaagaaa
    35281 tcattccttt agaagaatta tatcggattt gccaattcgt tcgtgatata acaaaagatg
    35341 atccgtatat gattggccga atcattgcac gtccgtacgt gggtgaacca ggagacttca
    35401 cacgaacaag caatcgccat gattatgcgt tgaatccatt cggacacaca gtccttgatt
    35461 ctttgaaaga agcaggaaag gacgtgattg ctgttggaaa gatcaacgat attttcaacg
    35521 gacaaggaat cactgaatct gtccgcacga aaagcaatat ggatggcgtt gaccagctgc
    35581 tgaaagttat gaaaaacgat ttttcaggaa tcagctttac caatttagta gattttgatg
    35641 cattatacgg tcatcgtcgg gatgtagtcg gctatgcgca tgcgattgaa gaatttgact
    35701 tacgaattcc agaattgctt gaagcgatgg aagaagacga cttgctaatg attacagccg
    35761 atcacggaaa cgatccgacg tttactggta ccgatcatac gcgagaatat gtaccgttat
    35821 tggtttacag taaaaaaatg aaagaacaag gggcattgcc tcaaggatat tattcagata
    35881 tttcagcaac gattgctgag aactttagtg tttcttcgac tgaaaatggc gaaagcttct
    35941 tgaaattatt aaaataatct ttttaaatag gagaaagcaa atgaccaagt taagcgagat
    36001 gttacaagaa acgacccagt ttatccttga taaaggagta aaagaaattg attttggttt
    36061 gattctaggt tcaggattag gtgaattagc agatgaaatc gaagatgctg taatgatttc
    36121 ttatgatgag atcccgttct ttcctgtttc gacagtagtt gggcatgcag gaaagctagt
    36181 ttatgggtct ctggcaggca agaaagtgtt agccatgcaa gggagattcc actactatga
    36241 aggtcattcc atgcaaacag tgacctatcc agtacgtgtg atggccggac taggggccca
    36301 ttcagtcatt gtgactaatg catgtggtgg tgtcaacgaa tcatttgtac caggagattt
    36361 gatgctgatt accgatcata tcaattttac tggtgaaaat cctttgatcg gtccgaatga
    36421 agatgcaatg ggccctagat ttccagatat gagtcaagct tatacgcctg actatcaagc
    36481 aacagcaaaa gcagcagcag aaaaactagg tttggatctt aaagaaggcg tatatatggg
    36541 ctattctgga ccaacttatg aaacgcctgc ggagatccga atgtctcgga caataggagc
    36601 cgatgcagta gggatgtcga ctgttccaga agtcatcgta gcagctcaca gcggattaaa
    36661 agtgttagga atctcttgta ttaccaactt agcagcaggt atgcaagcga atctgagcca
    36721 tgaagaagtt gtagaaacaa ctcagagagt caaacaatct tttaaagcat tggttaaaga
    36781 aacattgaca ttattgtaat aggaggaaca ataaaatgag tgtgcatatt gaagcgaaag
    36841 aaggcgagat cgccgataag attttacttc cgggagatcc tttgcgagct aaatatattg
    36901 cggagacttt tttggaagat ccagtttgtt acaatcaggt acgcggtatg ttaggcttta
    36961 ccggcaaata taaaggagaa cgtatttctg ttcaaggaac aggaatggga atgccatcag
    37021 ccaccatcta tgcccatgaa ttgatccagt cgtatggtgt aaagaaattg attcgagtag
    37081 gtacatgcgg tgcattgtca aaagacgtcc atgttcgtga tttagtacta gcacaaggtg
    37141 cagcgaccag ttcttcgatg atcgaaaaaa atttccaagc ctttcatttt cctccaatca
    37201 gtgatttcaa tctattactg aaagcatatg agatagctaa agaaaagggc tatacggttc
    37261 atgtaggaaa tgttctttcg gaagattctt tctacaaaga tgatttgaca gagacgttcc
    37321 aattagctga acttggcgtt ttaggagtgg aaatggaagc agcggctctt tattacttag
    37381 gcgcgaaata ccatgtgcag acattaagtt tgatgaccgt tagcgaccat ttgatcaccg
    37441 gtgaagaaac aacagctgca gaacgtcaat ctacgttcaa tgaaatgatc gaagtaggat
    37501 tggaaacagc gatagcagaa taagaaggaa atgaaaaagc tgccctgcat taagtaataa
    37561 gaacatccaa gcaaaaatag ctcctcatgt ttttgacttg gctggactta ttattgcaaa
    37621 tgtaagcttt tgaacaccgt ttaccaagag gttgtgaatc tgccgtttaa ctctgagtca
    37681 caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtgac ttgtgaccga
    37741 gaagttggca ggagaaaacc gtttatacga aaaaagggac tgtgacaaat cgtgtcacag
    37801 tccctttttt atagtgtttt ttataggtag tattttttag caactgttaa gtcatcattt
    37861 aattcataaa caagtggttg acctgttgga atttcaagat ccatgatgtc ttcgtcagag
    37921 ataccttcga tatgtttagc tagggcgcgt aatgagttac catgtgcagc tactaaaaca
    37981 gttttgttgt ctagtaatgc tggagcaatt tcatcttgcc agaatggcaa agcgcgttct
    38041 aatgtcactt tcaagttttc tccaccagga atatcgcgtt tgtctaacat tgcgtaacga
    38101 cggtcatttg ctgcagaacc ttcgtcagtt tcttccatta atggaggaag agtatcgtaa
    38161 gaacgacgcc agatgtgcac ttgttcgtcg ccgtattttt cagctgtttc ttttttgttc
    38221 aaaccttgta atttaccata gtgacgttcg tttaagcgcc atgatttgat ttgtggtacc
    38281 caaagttgat ctgaatattc taagatcaag ttacatgttt tgattgcacg agttaaaaca
    38341 gaagtgtaag caacatcaaa ttcgattcca gcttctttga ttttgcgtcc gccttctttt
    38401 gcttcttcga ttccttctgg tgctagattt acatcagccc aaccagtaaa ttggttcaat
    38461 gcattccatt cactaagacc gtgacgagaa aaaactaatt ttggcatgtt tagctctcct
    38521 tttaagatag gtttatattt ctgaaatttt cagttctgtt ttattgtaca attttttgga
    38581 agagatttcc atcgaaaaat tagataagat tctatgagaa aacaagtaga gaatataaaa
    38641 aaacgaacag tgcccacgca actgttcgtt tttaggtatt agatgcataa ttgctcgatt
    38701 tctttttcag gtaaattgat atatttataa catgttccaa ctgaaacacc gcattttgaa
    38761 gaaataaatt ggatcgtttc ttttttttca taatagagac gtcggatttt tttgatcgtt
    38821 tttgcatcga tttttggtct tccgccgatt tttccttttt tacgagcttc atctaatcca
    38881 actaatgtac gttctttgat caatgcgcac tccatgtttg ctaggttttc cattaattgg
    38941 aaatagattt ttcccatttc gcgcgtatcg attccttcat caagactaat caagtgcagc
    39001 ccgcgatctt tgaataattg cgtgagttct gttaattgcc gcgtagattt gcctaatcga
    39061 tgaagttggc aaatgactag tgcatcgcct tgttgcatgt cagcgatcac tgactccaaa
    39121 tgaacagcag tagaatcatt ttgttccact tcatatgtct catggaaaat ttcttgacaa
    39181 ccaaagtcag ataattgatc aacctgagtt gttaaatcaa cgtcatttat ggttgtgcgt
    39241 gcataaccaa taattttcat ggtgattcct ttctagcagt gattttctaa ctggatataa
    39301 cagtaaaaat gtagcataaa gtacgtcaaa aagatagttt tttcgcaaat tttccgctgt
    39361 ctttttttat tggatgatca agcagttttt ctttatttac gacggattgc gtcaagaatc
    39421 tcaacgcctt tttctgagcc gacaactact ttagaaacca tgtttaggaa aagcccatgt
    39481 tctactaccc caacaagttc atctaaatag gtagctaagc tttctggctg ttcgatgact
    39541 tctagatgca gatcaatgat gtaatgacca ccatctgtgg ttaagacttc tccgttttcg
    39601 tctgtacgca agacgggttg gaatcttttt tcttcaaaaa tatgaagtag ctgttgggag
    39661 ccataaggga tcacttcaac tgggagtggg aacttcccaa gtttatcgac taatttagaa
    39721 gaatcaacga tccaaatcgt ttcttttgag tacgtagcga ctattttctc gaaaagcaaa
    39781 gcagcgccgc cgcctttgat cccttgaaaa tcagcactga tttcatcagc accgtctatt
    39841 gtcaaatcga ctacggggac ttcatcaata ctctttaacg gtattcctaa tttttccgct
    39901 tgttcttttg tcgcatttga agtagtaact cctgtgatac gtaaaccttc ttcacgcata
    39961 cggcgaccaa tctcttctac catataatag gcggttgaac cggtcccgag acctacgatc
    40021 atcccgtcct ttacgaattt cgcggcttca atgccagcta attgttttaa attcatcttt
    40081 gcgtccacct ttttttagtt tgagcatcgt gctttcctca ctattttagc gtgatttacg
    40141 gtaaaaagat accattcttt tttattccaa taaagctttt tcaaaaaaaa ttgcatctct
    40201 tgttgacatg ttttttcatt cgtgatattc taacaaaggt gctttatcta caggtttctg
    40261 tgaagaaacg tgctgactgt ttatcaaagc atatttgata aggatgcaga cattgcattt
    40321 attttttatc acaaaaaaag aaccacctgg atgtgtggaa ctagacgcaa atcgtgggaa
    40381 ggaggaaaca aggaatgcct acaattaacc aattagtacg taaacctcgt aaatcaaagg
    40441 tggaaaaatc taattcacct gctttgaaca aaggatataa cagctttaag aaaactcaaa
    40501 ctaacgtaaa ctcacctcaa aaacgtgggg tagcaactcg tgtgggtaca atgacaccta
    40561 aaaaaccgaa ctcagcttta cgtaaatatg cacgtgttcg tttgtcaaac ttaattgaag
    40621 ttactgctta tatcccaggg attggtcata acttacaaga acacagtgtt gtattattac
    40681 gcggtggtcg tgtaaaagac ttaccagggg tacgttacca tatcgttcgc ggtgctttag
    40741 atactgctgg tgttaacgac cgtaaacaaa gccgttctaa atacggaact aaaaaaccta
    40801 aagcttaatt ttaattatta aacaaatgaa acttgcttct actatataga agtaattact
    40861 atgaacaata tttcggaagg aggagttacg gatgccacgt aaaggtcctg ttgcaaaacg
    40921 tgatgtttta ccagatccta tttataactc aaaattagta actcgcttga tcaaccgtgt
    40981 aatggttgac ggaaaacgcg ggattgcagc taacattatc tataatgcct ttgacttgat
    41041 caaagaatct acaggtaacg atccattaga agtgtttgaa caagcaatga aaaacgttca
    41101 acctgttctt gaagttaaag cacgtcgtgt tgggggttca aactaccaag taccagttga
    41161 agttcgccct gaacgccgcg ttactctagg tcttcgttgg gtagtaaact acgctcgctt
    41221 gcgcggtgaa cacacaatgg aagaacgctt agcaaaagaa atcatggatg ctgcaaacaa
    41281 cacaggtgct tctgttaaaa aacgtgaaga cactcataaa atggctgatg ccaaccgtgc
    41341 gtttgctcac tatcgctggt aagattctct ctgtttggtc ggcttttata agtcgacctc
    41401 agatagtgtc cttattttta gcaactagat agtaaagaga ggagaaacaa ggagaatgac
    41461 cagagaattt tctttacaaa acactcgtaa tatcggtatc atggcccaca tcgatgctgg
    41521 taaaacgact gctactgaac gtatcttgta ctatactggt aaaatccata aaattggtga
    41581 aactcatgaa ggagcttcac aaatggactg gatggaacaa gaacaagaac gtggtattac
    41641 gatcacttct gctgctacta cagcacaatg gaagggtcac cgaatcaaca tcatcgacac
    41701 accaggacac gtagacttca cagttgaagt tgaacgttca ttgcgtgtac ttgatggtgc
    41761 tgtaactgtt cttgatgcac aatcaggtgt tgaacctcaa actgaaacag tttggcgtca
    41821 agcaacaact tatggtgtac ctcgtatcgt atttgcaaac aaaatggaca agatcggtgc
    41881 tgacttctta tattcagtat caactttaca tgaccgtttg caagcaaacg ctcacccaat
    41941 ccaattacca attggtgcgg aagacgactt cacaggaatt atcgaccttg taacaatgaa
    42001 ggctgaaatg tatacaaacg atcttggaac agagatcgaa gaaacagaaa ttcctgaaga
    42061 ataccgcgaa ttagctgaag aatggcgcga aaaattggtt gaagctgtag ctgaaactga
    42121 tgaagaactt actttgaaat acttagaagg tgaagaaatc actgaagctg agttaaaaga
    42181 aggtatccgc cgcgcaacag ttaacgtaga attctaccca gtactatgtg gttcagcatt
    42241 taagaacaaa ggggttcaat tactattgga cgctgttctt gattacttgc catcaccgtt
    42301 agatatccca gctatcaaag ggattgaccc taaaactgat gaagaagtag aacgtcctgc
    42361 agacgacagc gctcctttct cagctttagc atttaaagtt atgactgacc cattcgtagg
    42421 tcgtttaact ttcttccgtg tgtactctgg tgttttacaa tcaggttcat acgtacaaaa
    42481 cgcaacaaaa ggcaaacgtg aacgtgttgg tcgtatccta cagatgcatg ccaactctcg
    42541 ttcagaaatc tctgaagttt acgctggaga tatcgctgct gctgttggtt tgaaagacac
    42601 aactactggg gacacactat gtgatgaaaa gagtctagtt attcttgaat ccatggaatt
    42661 cccagaacca gttatccaag tcgctattga acctaaatca aaagctgacc aagataaaat
    42721 gggtgtggct ttacaaaaac tatctgaaga agatcctact ttccgtgctg aaacaaacgt
    42781 ggaaacaggc gaaacaatca tcgctggtat gggtgaactt cacttagata tcatcgttga
    42841 ccgtatgcgt cgtgaattca aagttgaagc taacgtaggt gcgcctcaag tatcttaccg
    42901 tgaaactttc cgtgctggca ctcaagccga aggtaagttt gtacgtcagt ctggtggtaa
    42961 aggtcaatac ggtcacgtat ggattgaatt tacaccaaat gaagaaggtg ctggtttcga
    43021 atttgaaaat gcgatcgtcg gtggggttgt tcctcgtgaa tacattccag ctgttgaaac
    43081 tggtttgaaa gatgctatgg aaaatggtgt cttagctggc tatccattag tagatatcaa
    43141 agctaaactt tacgatggtt cataccatga tgtcgattca aatgaaactg ccttccgtgt
    43201 tgctgcttct atggcattac gtgcagcagc taagaaagct aatccagtaa tccttgaacc
    43261 aatcatggct gtagaagttg ttatccctga agattattta ggtgatgtta tgggtcacgt
    43321 aactgctcgt cgtggacgtg ttgaaggtat ggaagctcgc gctggcggcc aacaagttgt
    43381 tcgtgcgatg gttccacttg ctgaaatgtt tggttatgct acaactcttc gttctgctac
    43441 tcaaggtcgt ggtacattta caatgacatt tgaccactac gaagatgtac caaaatcagt
    43501 acaagaagaa atcattaaga aaaacggcgg aaaagctgaa taatttctta aaaccggata
    43561 gtcctgcaaa gagattatcc aaagagacta tatttttaat atagtttcgt gtaaaataat
    43621 tatcgatgat atgggcatgt ggtgtacctt gtgtacatca tatacctatc agacaaataa
    43681 aaaatatatt gtatttttag gaggacattt taaaatggca aaagaaaaat ttgaccgttc
    43741 taaaccacac gttaacattg gtactatcgg acacgttgac catggtaaaa ctacattaac
    43801 agctgcaatc acaactgtac tatctaagaa aaacggcggc caagctatgg cttacgatca
    43861 aatcgatggt gctccagaag aacgcgaacg cggaatcaca atctcaacag ctcacgttga
    43921 gtatgaaaca gatacacgcc actacgctca cgttgactgc ccaggacacg cggattacgt
    43981 taaaaacatg atcactggtg ctgctcaaat ggacggagct atcttggtag tttctgctgc
    44041 tgacggccca atgcctcaaa ctcgtgaaca catcctattg tctcgtcaag ttggtgttcc
    44101 ttacatcgtt gtattcttga acaaagtaga catggttgat gacgaagaat tactagaatt
    44161 agttgaaatg gaagttcgtg acctattaac agaatacgaa ttccctggtg acgatgttcc
    44221 tgtagttgct ggatcagctt tgaaagctct agaaggcgac gcttcatacg aagaaaaaat
    44281 tcttgaatta atggctgcag ttgacgaata catcccaact ccagaacgtg acaacgacaa
    44341 accattcatg atgccagttg aagacgtgtt ctcaattact ggacgtggta ctgttgctac
    44401 aggtcgtgtt gaacgtggac aagttcgcgt tggtgacgaa gttgaagttg ttggtattgc
    44461 tgaagaaact tcaaaaacaa cagttactgg tgttgaaatg ttccgtaaat tgttagacta
    44521 cgctgaagct ggagacaaca ttggtgcttt actacgtggt gttgcacgtg aagacatcca
    44581 acgtggacaa gttttagcta aaccaggtac aatcacacct catacaaaat tctctgcaga
    44641 agtatacgtg ttgacaaaag aagaaggtgg acgtcatact ccattcttca ctaactaccg
    44701 tccacaattc tacttccgta caactgacgt aacaggtgtt gttgaattac cagaaggaac
    44761 tgaaatggtt atgcctggcg acaacgtaac aatggaagtt gaattaatcc acccaatcgc
    44821 tatcgaaaac ggtactaaat tctcaatccg tgaaggcgga cgtacagttg gtgccggtgt
    44881 cgttacagaa atcaaagctt aattcactta agttttaaag taaagcaaca tttattcgga
    44941 cgtaatcgct cggaacgaag gtcttaggat ctttgttccg agctttttta tttattgcag
    45001 gatcaggaaa aaagacagga gtattataaa tagaagaaac acgaaataaa agagtcagta
    45061 ttttctaaat gaaactttat gaaaacaaaa tgttttttac aagaaaaagc cttgctttgt
    45121 gagtttatat atattataat gacaaaggtg cgtttacttt agtgaattgc acagacgtaa
    45181 tcagaatgat ttcgtcggct aagaaacgag aggttgcgac acgcccggac gctttgccac
    45241 gaacgagcgt gacggaaatt ttcgtggagc tatgtctact tttcaaaata ggcgaaggag
    45301 ggaacaagat ggcaaaacaa aaaattcgta tccgtttaaa agcgtatgaa caccgtattt
    45361 tagatcaatc agcggataaa atcgtggaaa ctgcaaaaag aactggagct agcgtgtctg
    45421 gtccaattcc attaccaact gaacgcagtc tttacacaat catccgtgcg actcataaat
    45481 acaaagattc acgcgaacaa ttcgaaatgc gtacacacaa acgtcttatc gacattgtga
    45541 acccaacacc aaaaactgtt gatgctttga tgaagctaga cttaccatct ggtgtaaaca
    45601 tcgaaatcaa attataaaac taaaacaaaa ataatggagg tgtactcatg accaaaggaa
    45661 tcttagggaa aaaagtggga atgacacaaa tcttcactga atctggtgaa ttaattccag
    45721 taactgttgt agaagctact ccaaacgtag tactacaagt gaaaacaatg gaaacggatg
    45781 gctacgaagc tattcaagtt ggttaccaag atatgcgtga agttttatca aacaaacctg
    45841 cgaaaggtca tgttgcaaaa gcaaacacgg ctcctaagcg cttcattcgt gaattcaaaa
    45901 atgttgagct aggagaatat gaagtaggaa aagaaattac agtagatgtt ttccaagcag
    45961 gagacattat tgatgtaaca ggtactacga aaggtaaagg attccaaggg gttatcaaac
    46021 gccacggaca aagccgcgga ccaatggctc acggttctcg ttaccatcgt cgtcctgggt
    46081 caatgggtcc agttgcacct aaccgtgtat ttaaaaacaa acgtcttgct ggccgtatgg
    46141 gtggcaaccg cgtaactatc caaaacttgg aagttgtacg tgtcgatgca gaaagaaatg
    46201 ttatcttgat caaaggtaat gttcctggag ctaaaaaatc tttaattact atcaaatcag
    46261 ctgtgaaagc taaataattg taggaagaaa ggaggaacta aggaatgccg aatgtagcat
    46321 tattcaaaca agatggaagc caaaacggtg aaatcacact taacgaagaa atcttcggaa
    46381 ttgaacctaa tgaaagtgtt gtttacgatg caatcgtaat gcaacgtgcg tcattaagac
    46441 aaggaacaca cgcggttaaa aaccgtagcg ctgttcgcgg cggcggacgt aaaccatggc
    46501 gtcaaaaagg aacaggtcgt gcacgtcaag gatctatccg ctcaccacaa tggcgtggag
    46561 gtggcgtagt ctttggacca acaccacgtt cttacagcta caaacttcct aaaaaagttc
    46621 gtcgtttagc aatgaaatct gtattgtcag aaaaagttgc tgaaaacaac ttggtagcaa
    46681 tcgaaggctt gaacttcgac gcaccaaaaa caaaagaatt caaacaagtt cttgctaact
    46741 tatctatcga ctctaaagta ttggttgttc tagaaaaagg taacgacttt gctgctttat
    46801 cagcacgtaa cttaccaaac gtttctgtag taacttctga taatgtgagt gtgctagacg
    46861 ttgtatcaaa tacaaaagtg ttagcaacac aaactgctct tactcaaatt gaggaggtgc
    46921 ttgcataatg aacttactag acgtaatcaa acgcccagtg atcactgaaa aatcaatgct
    46981 tgccatggat gacaagaaat acacttttga agtggacact cgcgcaaaca aaactttagt
    47041 aaaacaagcg gtagaagctg cttttgacgt taaagtcaaa aacgtgaaca tcgtgaacgt
    47101 acgtgcgaaa ttcaaacgta tgggcaaata tgcaggatat acaaaaaaac gtcgcaaagc
    47161 gatcgttaca ttgactgaag attcaaaaga aatccaatta ttcgaagctg ctgaataagc
    47221 actaatagat aactcattaa attaggaggg aaaaacgtgg cgattaaaaa gtacaaacct
    47281 acctcaaatg gtcgtcgtaa catgacaggt tctgattttg ctgaaatcac aacatcaaca
    47341 cctgaaaaat cattgttaca accattgaaa aaccatgctg gacgtaacaa caacggccgc
    47401 atcactgtac gtcatcaagg tggcggacac aaacgccaat atcgcgtgat cgacttcaaa
    47461 cgtaacaaag ataacgttgt tgcaactgtt caaacgatcg aatatgatcc aaaccgttca
    47521 gctaacatcg cgttagtaca ctatgaagat ggagtgaaag cttacatctt agcacctaaa
    47581 ggactagaag tgggtatgaa acttgtttca ggtccagaag cagatatcaa agtcggaaat
    47641 gctcttccat tagaaaacat tccagttggt actgttatcc acaacattga aatgaaacct
    47701 ggtaaaggtg gacaattgat ccgttctgct ggtacaagtg ctcaagtact tggtaaagaa
    47761 ggcaaatacg tattgatccg cttgaactct ggtgaagttc gtatgatctt agctgcatgc
    47821 cgtgctacaa tcggttctgt aggtaacgaa caacacgaat taatcaacat cggtaaagct
    47881 ggacgctctc gttggatgcg taaacgccca actgtacgtg gtagcgtaat gaaccctaat
    47941 gatcacccac acggtggtgg tgaaggtaaa gctcctatcg gacgtaaagc accagtttct
    48001 ccttggggtc aaccagctct tggttacaaa actcgtaaca aaaaagctaa atcagacaaa
    48061 cttattgttc gtcgtcgcaa aaataaataa ttactttgac catgtgtcgc acattttgag
    48121 aggaggttca ccatgggtcg tagtttaaag aaaggacctt ttgtcgatga gcatttaatg
    48181 aaaaaagttg aagctcaagc aggggttgaa aagaaaaaag ttatcaaaac ttggtcacgc
    48241 cgttcaacag ttttcccaag ttttgttgga tataccatcg cagtttatga tggacgtaaa
    48301 catgtaccag tttacatcca agaagacatg gtaggacaca aattaggtga atttgcacct
    48361 acaagaactt atcgtggaca tgctgctgac gataagaaaa cgaaacgcta atttgagggg
    48421 aggataaatc caaatggcag aacaaatcac atcagctaaa gcaactgcaa aaacagttcg
    48481 cacttcacct cgaaaagccc gtttagtaat tgaccttatc agaggtaaaa gtgtcgcaga
    48541 tgcaatttca atcttgaaat tcacaccaaa caaatctgct ggaatcattg aaaaagtatt
    48601 gatgtcagca gttgcgaatg cagaaaataa ctttgactta gatgttgaaa acttggtagt
    48661 aagcgaagct tttgttaacg aaggacctac aatgaaacgt ttccgtcctc gtgcaaaagg
    48721 atcagcttct ccaatcaaca aacgtacaag tcatatcacg gtagtcgtat cagaaaaata
    48781 aggagggata atcagtgggt caaaaagtac atccaattgg aatgcgtgta ggcatcatcc
    48841 gcgactggga tgctaaatgg tatgctgaaa aagagtatgc tgagttctta cacgaagatt
    48901 taagaatccg taaatttatt tcaactaaac ttgctgatgc tgctgtatca acagttgaaa
    48961 tcgaacgcgc aacaggtcgc gtaaacattt caattcacac agctaaacca ggtatggtta
    49021 ttggtaaagg cggttctgaa gtcgaaagcc taagaaaaga attaaacaaa ttaactggta
    49081 aaagaatcca tatcaatatc gtggaaatca aaaaaccaga tctagatgca aaattagtag
    49141 gtgaaggaat cgcacgtcaa ttagaaaacc gtgttgcttt ccgtcgcgct caaaaacaag
    49201 ccatccaacg ctcaatgcgt gctggcgctc aagggatcaa aactcaagta tctggtcgtc
    49261 taaacggagc agatatcgct cgttcagaag gatactcaga aggaactgtt cctcttcata
    49321 ctttacgtgc ggacattgat tacgcatggg aagaagcaga tacaacatac ggaaaactag
    49381 gagttaaagt gtggatctat cgtggagaaa ttcttccaac taaaaaaaac actgagaaag
    49441 gagggaaata atcatgttag tacctaaacg tgtaaaacac cgtcgtgaat tccgcggaaa
    49501 aatgcgcggg gaagctaaag gcggaaaaga agtagcattc ggtgaatacg gtttgcaagc
    49561 tgttgattca cattggatca caaaccgcca aatcgaagct gctcgtatcg caatgactcg
    49621 ttacatgaaa cgtggtggga aagtatggat taaaattttc cctcacaaat cttatactgc
    49681 caaagcaatt ggggtacgta tgggttctgg taaaggggca cctgaaggat gggttgcacc
    49741 agtaaaacgt ggtaaaatca tgtttgaaat cgcaggcgtt cctgaagaag tagctcgtga
    49801 agcgttacgt ctagcttctc acaaattacc aatgaaaact aagatcgtaa aacgtgagga
    49861 aatgggtggt gaatcgaatg aaggttaaag aaatcagaga attaaccact gccgaaatgc
    49921 ttgatcaaga aaaacaatta aaagaagaat tgtttaatct tagattccaa ttagcaacag
    49981 gtcaattaga aaacactgca cgtattaaag aagtacgtaa atcgattgca cgcatcaaaa
    50041 ctgtgttgcg tgaacaagct aagtaattat ggaaggaggc cattaagcgt atgactgaag
    50101 gaagaaatca acgcaaagtt tatcaaggtc gcgtggtttc agacaaaatg gataaaacaa
    50161 ttaccgttgc tgtcgaaaca aagaaaaacc accctatcta tggcaaacgc atgaactatt
    50221 ctaagaaata caaagtgcat gatgaaaaca acacagcaaa agttggcgac atcgtgagaa
    50281 ttatggaaac tcgtccatta tcagctacaa aacgtttccg tttgttggaa gtagtcgaag
    50341 aagcagttat tatctaataa cacgagattt tcctatatag attgaatgca aaatctgaaa
    50401 ggaggataca caacgtgatc caagcagaaa gtcgtttaaa agtcgctgat aactcaggcg
    50461 cacgtgaaat tttgacgatc aaagtccttg gtggatctgg tcgtaaaact gctaacatcg
    50521 gtgatgtgat cgttgctacg gttaaacaag caacgccagg tggggttgtc aaaaaaggtg
    50581 acgtcgttaa agccgttatc gttcgaacaa aatcaggagc tcgtcgtaca gacggttcat
    50641 atattaaatt tgatgaaaat gctgcagtga ttattcgtga tgataaaagc cctcgtggaa
    50701 cacgtatctt tgggccagtt gcacgtgaac tacgtgaaaa caacttcatg aagatcgttt
    50761 cactagcacc agaagtttta taatcttgag acacttatca aaggaggtgc gaaacagtta
    50821 tgtttgttaa aaaaggcgat aaagttaaag ttatcactgg aaaagacaaa aacaaagaag
    50881 gcgttgtact agcagcgttc ccgaaaaaag ataaagttat tgtcgaaggt gtaaatgtcg
    50941 ttaaaaaaca ccaaaaacct tctcaagctg ctcctcaagg tggaattgtt gagatggaag
    51001 cgccaattca tgtttctaac gtgatggtgg ttgactctac tggtgtagct ggccgagttg
    51061 gctacaaaga agtagacggc aaaaaagtcc gtgtttctaa aaaaaccggt gaagttttag
    51121 ataaataaaa gtttaaggaa ggagggtctt actgaatgaa ccgcctaaaa gaaaaatatc
    51181 ttaaagaagt aactccatca ttgatggaaa aatttaacta tagctctgtt atgcaaacac
    51241 ctaaagttga aaaaatcgtc atcaacatgg gtgttggtga tgcggtatca aacgctaaaa
    51301 acttagataa agcagttgaa gaattaactt tgatcactgg tcaaaaacca atgattacaa
    51361 aagctaaaaa atcaatcgct ggattccgtt tacgtgaagg aatgccaatt ggtgcaaaag
    51421 ttacattgcg cggagaaaga atgtacgaat tcttagacaa attggtttct gtttcactac
    51481 cacgtgtacg tgacttccat ggtgtaagta aaaaagcctt tgacggtcgt ggaaactata
    51541 ctttaggtat taaagaacaa ttgatcttcc cagaagtaga ttatgattta gtagataaag
    51601 tacgtggtat ggacatcgtt attgtaacaa cagcaaactc tgatgaagaa tctcgtgagt
    51661 tgttgacaca attaggcatg ccattccaaa aataattaaa ggaggcgaac tacgtggcta
    51721 aaaaatcaat gattgctaaa aacaaacgtc ctgcaaaatt ttcaacacaa gcttatactc
    51781 gttgcgaacg ttgcggacgt ccacattcag tttatcgtaa gttccatctt tgccgtattt
    51841 gcttccgcga acttgcctat aaaggtcaaa ttcccggcgt gaagaaagct agctggtaaa
    51901 aagtaaattc gcataagaag gaggtaaaag atcaatggtc atgacagatc caattgcaga
    51961 ttttctaact cgtatccgta acgcaaacat ggttaaacat gagtctttag aagtacctgc
    52021 atcaaaaatt aaacgtgaca tcgctgaaat cttgaaacgt gaaggtttcg ttcgtgatgt
    52081 tgaatacatc gaagatgaca aacaaggcgt gatccgtgtt ttcctaaaat ttggtaaaaa
    52141 cggcgaacgt gttatcacaa acttaaaacg tatctctaaa ccaggtttgc gtgcttatgt
    52201 caaagctgac gaagtaccaa aagtattgaa cggtttaggt atcgcaatca tttcgacttc
    52261 tgaaggtgtt gtcactgata aagaagctcg tgaaaaaaat atcggcggcg aagttatcgc
    52321 ttacgtatgg taatcaagta gaatctacaa ggaggtgtct ttaagtgagc cgtatcggaa
    52381 ataaagtcgt tgttatccct gaaggagtaa cagttactca agacggaaac aacgttacag
    52441 ttaaaggacc aaaaggtgaa ttgactcgta ctttttcagc agatatcaaa atgaatatcg
    52501 aaggaaacga agtaactttc actcgtccaa acgacagtaa agaaatgaaa acaattcatg
    52561 gaacaactcg tgcgaacttc aacaacatgg ttgtaggtgt cagcgaaggt ttccaaaaag
    52621 cgttagaact aatcggggtt gggtaccgtg cacaattaca aggatcaaaa cttgtattga
    52681 acgttggtta ctcacatcca gtagaaatca caccaccagc tggagtaact gttgaagtac
    52741 cagctaacac acaagtaatt gttaaaggtg cgaacaaaga agaagttggc gaattagctg
    52801 caaacattcg tggaactcgt cctccagaac cttataaagg taaaggtatt cgttatgttg
    52861 gcgaatatgt acgccgtaaa gaaggtaaaa ctggtaaata atcgtttaga aaaattgcat
    52921 agaagccagc agcaggaaaa aggcatttgg ctgaagttta ccttcaaaaa aatacatttt
    52981 tacttgtgcc gcagcttcta tttttcgaaa cgtatttact gcttgaaata gtagtacaat
    53041 aaaaataaag aggtgacaat tgtgattaca aaaccagata agaacaaaac acgtcaaaag
    53101 agacatcgtc gtgtacgtaa caatatctct ggtactgctg agcgcccacg cttgaacgtt
    53161 tttcgttcta acaaaaacat ctacgctcaa attattgatg acgtagcggg tgtaacgcta
    53221 gcaagtgcct ctaccttgga taaagaaatt tcaggtggaa caaaaacaga agcagcacaa
    53281 gctgtcggta aactagttgc tgaacgtgca gctgaaaaag gcattaaagt agtagtcttt
    53341 gaccgtggtg gataccttta ccatggccgt gtgcaagctt tagctgaagc tgctcgcgaa
    53401 aatggactag aattttagaa gaaggaggaa taccattcat ggtttatatc gatccaaaac
    53461 atttggaatt agaagaccgc gttgttgcaa ttaaccgtgt aacaaaagtt gttaaaggtg
    53521 gacgtcgtct acgttttgct gctttagttg ttgtcggtga caaaaacgga cacgtagggt
    53581 ttggtacagg taaagctcaa gaagttcctg aagcaatccg taaagcaatt gaagatgcga
    53641 agaaaaactt agttgaagta cctatggttg gttcaacaat cccacacgaa gtaatcggtg
    53701 cttttagtgg tggtagaatc ctaatgaaac ctgctgtaga aggttctggg gttgctgctg
    53761 gtggaccagt tcgtgccgta ttagaattag ctggggtagc agatatcact tctaaatctt
    53821 taggctcaaa tacaccaatc aacgttgttc gcgcaacagt tgaaggtttg aaacaattga
    53881 aacgtgcaga agaagttgca gaacttcgcg gcaaatcagt tgaagaatta atcggataag
    53941 gaggacaaca ataatggctg aattaaaagt tactttaaaa cgcagtatta tcggacgtcc
    54001 tcaaaaccaa cgcgatacag ttaaagcgtt aggtcttaca aagattaaca gttcagtggt
    54061 taagccttct aatgaagcaa ttaaaggcat gatcaatact gtttctcacc tagtggacgt
    54121 tgaagaaatt taatttagaa aaatcataac tagaacatta aggaggtgcc aaacctatga
    54181 aacttcatga attaaaacct gctgaaggtt cacgccaagt acgtaaccgt gttggtcgtg
    54241 gtacttcatc tggtaacgga aaaactgccg gacgcggaca aaaaggacaa aaagctcgtt
    54301 caggcggcgg tgtgcgttta ggatttgaag ggggacaaac accattgttc cgtcgtttac
    54361 caaaacgagg attcacaaac gtgaaccgta aagactatgc agtcattaat cttgatgtat
    54421 tgaaccgctt tgaagacgga gctgaagtaa ctcctgttgc tttagttgaa gctggaatcg
    54481 tgaaaaacga aaaagctgga atcaaagtat tagctaatgg ggaactaaac aagaaattaa
    54541 ctgtgaaagc agcaaaattc tctaaagcag ctcaagaagc aattgaagcg gctggtggat
    54601 caatcgaggt gatctaatgt ttagactatt aaaagatgct tttaaagtaa aagacattag
    54661 atcgaaaatc ctatttactg tatttgtgtt gtttgtattt cgcctaggtg cacatattac
    54721 tgtaccaggc gtaaatgctg cttcattgca aaacctttct tctttgccat ttttcaacat
    54781 gttgaacttg gtaagtggta gtgcgatgca aaacttttcc attttctcaa tgggggtttc
    54841 accatacatt actgcttcta tcgtcattca gcttcttcaa atggacatcg tgcctcgatt
    54901 tgttgaatgg tcgaaacaag gggaagttgg tcgtaaaaaa ctgaatcaag cgactcgata
    54961 tctgacatta gtattggcat ttatccaatc tgtcggtatc actgctggat tcaatcaata
    55021 cgctcaatta ggtttcgtga ataatcctaa cgtagcaact tacgtaacga tcggtttgat
    55081 tctaacagcc ggtacgatgt ttgttacttg gctaggagaa cagatcacag aaaaaggtat
    55141 cggaaatggc gtatcaatga tcatttttgc aggtatcatt tctagattgc ctgaaagtat
    55201 cagagaaatt tatgaagatt actttataaa tattgatcct tcagacatat ggaaatctgc
    55261 tatttttgtg gccattttac tagtagcggt cttgttgatc gtgacattcg taacattttt
    55321 ccaacaagct gaacgcaaga tcccgatcca atatacgaaa cgcgtagctg gcgcgcctac
    55381 aagcagctat ctgccgttga aagtaaatgc agctggagtt attccagtta tctttgctag
    55441 ttcgtttatt gctacgccaa atgctgtttt acaagcattg agcggtagat tcggttctga
    55501 aaactggtac aaagtgatga tggagatctt taactataat acagcacctg gtgctacgat
    55561 ttatacgatt ctgatcgttg ccttcacttt cttctacgcc tttgttcaag taaaccctga
    55621 gaaattagcg gaaaacttgc aaaagcaagg aagttatata ccaagcgtac gccctggtaa
    55681 ggggactgaa gagtatgtct caagattact gatgcgttta agtacagttg gtgcagtctt
    55741 ccttggttta gtggcattgc ttccaatcat tgctcaaatg gtttgggatc ttccacaatc
    55801 aatcggatta ggcggtacaa gcttactgat cgttatcggt gtagctttag aaactgcgaa
    55861 acagttagaa ggcttaatgc tgaaacgtaa atatgttgga ttcattgagt aagaaagcgt
    55921 gttgaggttt cccctcaaca cacgttctca cacatttatt aggagggaaa acaatgaacc
    55981 tcattttaat ggggctgcca ggcgcaggta aaggaacaca agctgaaaaa atcattgatg
    56041 cttatggtat tccgcacatc tcaacaggag atatgttccg cgcagcgatg caaaacgaaa
    56101 cagctcttgg cctggaagca aagtcttata tggataaagg tgcattagtt cctgatgaag
    56161 taacaaatgg aatcgtgaaa gagcgactag ctgaaccaga tacagagaaa ggcttcttat
    56221 tagatggctt tccacgtacg ctagatcaag caaaagctct ggacgcaatg ctaaaagatt
    56281 tgaataaaaa aattgatgct gtcatcgata tccatgttgg tgaagaaatc ttggtcgaac
    56341 gtctagccgg ccgatttatc tgcagcaatt gtggagcaac ttaccataaa attttcaacc
    56401 ctacaaaagt tgaagacaca tgtgatcgtt gcggtgggca tgaattctat caaagagaag
    56461 atgataaacc tgagacggtt aaaaatcgtc tggctatcaa catcaaaaat agtgaaccaa
    56521 tcttggctta ttataaagaa caaggtttgc taaacactat tgatggtgct cgtgaaatcg
    56581 atgctgtatt tgcagatgta caaaaaatca ttgaaaaata gcacgattgc ccgtagccga
    56641 cttgcattat gcagttactc ttgtcaagtt caataaatta tgatagaata tgtcagtccg
    56701 acttctagag aatcctctag atgatccatt ttgagaattt tgaggtggga actgcagttt
    56761 ccgccatttt atcgtgtgaa aatgcgaaac aagtacaagg aggtactgtg cgtggcaaaa
    56821 gaagatatga ttgaagtcga aggtacagtc gtcgaaactt tgccgaatgc aatgtttaaa
    56881 gttgaactag aaaacggaca ccaagttctt gctactgttt caggtaaaat tcgtatgcat
    56941 tacatccgta tcttacctgg tgacaaagta acggttgaat tgtctccata cgatcttaac
    57001 cgtggccgta ttacttatcg ctttaaataa ttgtactccg taaaactaca ggaggtatta
    57061 tcatgaaagt aagaccatca gtaaaaccaa tgtgcgaaca ttgtaaagta attcgtcgta
    57121 aaggacgcgt tatggtgatt tgcccagcaa atccaaaaca taaacaacgt caaggataat
    57181 tggaggtgct ataaatatgg ctcgtattgc aggagtagat attcctcgtg ataaacgtgt
    57241 agtagtttca cttacttata tctatggtat tggtaacact actgctaaaa agatcttagc
    57301 tgatgctggt gtatctgaag atgttcgcgt tcgtgaatta acgaatgaac aaacagatgc
    57361 tatccgtgca gaagtagata aattaaaagt tgaaggggat cttcgtcgtg aagtgaactt
    57421 gaacatcaaa cgtttgatgg aaatcggttc ttaccgtgga atccgtcatc gccgtggatt
    57481 gcctgttcgt ggacaaaaca cgaaaaacaa tgcacgtact cgtaaaggcc cagctcgcgc
    57541 tatcgctggc aagaaaaaat aattcttaag tgaaggaggt taaaacttca tggcagcaaa
    57601 aaaagtgaat cgtaaacgcc gtgtgaagaa gaatatagaa gcaggtattg cacatatcca
    57661 ttctacattc aataacacta tcatcatgat cactgatact cacggaaatg cattagcgtg
    57721 gtcatcagct ggttcattag gtttcaaagg aagcaaaaaa tcaactcctt ttgccgctca
    57781 aatggcagca gaaactgcta caaaagcagc aatggaacac ggattaaaga ctgttgaagt
    57841 aacagttaaa ggacctggtt ctggacgtga agcagcaatt cgttcattac aagctacagg
    57901 tttagaagtg actgcaattc gtgacgtgac tccagttcct cataatggtg cccgccctcc
    57961 aaaacgccgt cgtgtttaat gagtgccgct cattttgagt tttatcagta acgtcattga
    58021 acaagacact tttcgttttg aaaggggtaa agataagaat gattgagttc gaaaaaccaa
    58081 gaatcgcaaa aattgatgaa gaaaaagatt atggcaagtt catcgttgaa cctcttgaaa
    58141 gagggtatgg gactacttta gggaattccc tacgtcgtat tttattatct tctttgccag
    58201 gtgctgccat cactaatatt caaatcgatg gtgtactgca tgaattctct accatcaaag
    58261 gtgttagaga agacgtcact caaatcatct tgaacattaa aggcttagcg ctgaaaatgt
    58321 atggccaaga agaaaaaacc cttgaaatcg atattaccgg acctgctaca gtaactgctg
    58381 gcgatattat cgttgatagt gatgtagaaa ttcttaacaa agatatgtac atctgtagtg
    58441 tctctgaagg agctacgttc catgctcgct taacagtgaa acctggacgt ggttatgttc
    58501 aagcagatga aaataaaaaa gaagatatgc caattggcgt tcttccagtc gattcaatct
    58561 acacacctgt tcgtcgtgtg aactatcaag ttgagaacac acgtgttgga caccgtgaag
    58621 attttgataa attgacgatg gagatttgga cagatggttc aattgaaccg ttggaagcaa
    58681 tgagtttgtc tgcgaaaatc atgactgaac atttggatat ttttgtgaac ttaactgatg
    58741 aagcaaaaaa tgctgaaatc atggtcgaaa aagaagaaac acaaaaagaa aaaatgttgg
    58801 aaatgacgat cgaagagtta gacttgtctg ttcgctctta caattgtttg aaacgtgcag
    58861 gaatcaatac tgtacaagaa cttacaaata aatctgagcc tgaaatgatc aaagtccgta
    58921 acttaggacg taaatcatta gaagaagtta aagcaaaatt gcacgactta ggtttaggtt
    58981 tacgtaaaga agattaaaac cttttacgaa ggagggaaac caacgtgagt tatcgtaaac
    59041 taggacgcac atctagccaa cgtaaagcga tgttgcgtga tttaacaact gatttattaa
    59101 tcaacgaacg tattgtgact actgaagctc gtgcgaaaga agttcgctca actgcagaaa
    59161 aaatgatcac tttaggtaaa cgcggagatt tgcatgcacg tcgtcaagct gcggctttcg
    59221 tacgtaatga agttgccagc gtgcgtgaag aaaatgagga catcgtcatt gaatcagctt
    59281 tacaaaaact gttcaacgat attgcacctc gttacgcaga acgtcaaggc ggatacacac
    59341 gcattttgaa gacagaacca agacgcggtg atggtgcacc aatggttgtc ttagaacttg
    59401 tctaaaatca cactaataac atcactttat agatgattct tttagagtgt tatgatgttg
    59461 gaagatattt ttccgagtct agctcagcgc tgctcctcaa gcgaatatcg cttggggagt
    59521 aagcactcat cataaagtgt ttttttatac cttcaattac ctgtcatgac agatatgttt
    59581 gaaggcataa aaaaacattt taagcgagaa ataattgaaa attttgtctt tttttgatag
    59641 tgttagtagg aactttagga tgaagaagga gtaatcatgg agccaattat tgaattagaa
    59701 aagataaatt ataaatacca gccagatgat cttcgccccg cattgaaaga tgtctccttt
    59761 acaattgata aaggtgagtg gatcgctatt attggacaca atggttcagg aaaatcgaca
    59821 cttgccaaaa cgatcaatgg attgcttctg ccagaatcag ggatcgtgaa agtgggaaat
    59881 caaatattgg atgaagaaaa tatttggacg atccgacaga tggttggaat ggtttttcaa
    59941 aatccagaca atcagtttgt tggttcgaca gtagaagatg acgttgcttt tggtcttgaa
    60001 aatcaaggga ttcccagaga agaaatgcta gtgcgtgtga aagatgcact tgagaaagtt
    60061 agaatggctg agtttgcttc acgcgagcct gctcgtttat caggagggca aaaacaacgt
    60121 gttgccattg ccggcgtggt tgccttacga cctgatatca ttattttaga tgaagcaacc
    60181 agtatgctag atccagaagg tcgtgaagaa gtgatctcta cgatcaagaa gatcaaagaa
    60241 gaaagtcaat tgaccgttat atctatcact catgatattg atgaagcagc taatgccaat
    60301 cggatactag tgatgagaca aggcgaactt gtccgtgaag gtacaccaaa agaaattttt
    60361 tctgctggtc ctgaactgat cgacttaggt ctagatctac catttcctga aaaactgaag
    60421 agcgcactga aagaacgtgg ggttgatgtg cccagtgaat atatgacaga agaaaggatg
    60481 gtggattggt tatggacatc cgttttgaac aagtagactt cacttatcag ccgaatacac
    60541 catttgaaca aagagcctta tttgacatca atatgacgat caaagaaaac agttatactg
    60601 cattagtagg gcataccgga agcgggaaat caaccttact tcagcatttg aatgcgcttg
    60661 ttaagccaac aagcggtaca gtccatattg gagaacgaga tattcagccg gatacggata
    60721 ataagaattt aaagcccatc cgaaaaaaag ttggcatcgt ctttcagttt ccagaagcac
    60781 agctattcga agaaacggta gcaaaagaca ttgctttcgg tcctaaaaac tttggtgtca
    60841 gcgaagaaga agcactagtc ctagcaaaag aaacattaga acaagttggg ctggatgaaa
    60901 gctatttgga acgttcgcca tttgaacttt caggagggca aatgcgtaga gtagcaatcg
    60961 ctggtgtgct tgccatgagg ccggaagtac ttgtattgga tgaaccaacg gcaggacttg
    61021 atccccaggg tagaaaagaa atgatggaga tgttttggcg tcttcataag gaacagcaga
    61081 tcactattgt attagttacg catttaatgg atgatgtagc caattttgca gattatgtct
    61141 atgtgttgga aaagggacga atcgttaata gcggggagcc gcaagaggtc tttcaaaaca
    61201 ttgaatggct aaaagaaaaa caactaggcg tacctactgc caccgagttt gcagaagaat
    61261 taatggctaa agggatgaac tttgctacct tgcctttgac agctgaagaa ttagcagacg
    61321 ctatcgtcca ttatgctgga ggaaatgccc atgatgaata aattgatatt tggtcgttat
    61381 atgcctggag attccttgat ccatcgattg gatccccgag ctaaattatt agccagtttt
    61441 tattttatcg gaatcatttt tttagcaaat aattgggaaa cgtacctttt gttggcattt
    61501 ttcacattac tttctgtctt cttgtcaaaa gtagatttga aattttttat ccgaggcatt
    61561 cgcccattga tctggctaat cctcttcact gtagctttgc aggtcttgtt tacaagtggc
    61621 ggagaaactt attggagttg gggtgttttc catatcactg aatttggtgt gatgaacggc
    61681 ctctttattt tctgtcgatt cgtgttgatc atttttatgt cgactctact cacgcttact
    61741 acaccgcctt tggaattatc ggatgcgatt gagtacttgc ttcgtccatt gaaagccgta
    61801 cggttcccag tccacgaaat ttcattgatg ctgtcgattg ctcttcgttt tgtgcctaca
    61861 ttgatggacg aaacagaaaa gatcatgaac gctcagcgcg ctcgcggtgt tgattttggt
    61921 gaaggaaacc tagttcagaa aatgaaagca gtcattcctt tgctgattcc tttatttgtc
    61981 agcagcttca accgtgcgga agatcttgcg actgctatgg aagcaagagg ctacaaaggt
    62041 ggggaaggaa gaacgaaata ttgtgtattg cattggcata atagagacac gatggttatc
    62101 attgcttttg tattattaac tgtgctactg atctttttga gaggataaac gttcagtggg
    62161 ccgctatcta ttcttttctt gctgatctgt ttgcaagaaa ggatgcgagc agtgtatgac
    62221 aagaaatatt agggtctgtg gcagactaag gtcacaggcc tctttctttt atctgaaaag
    62281 aaagaacgaa aaaattttat aaaaaaatca ttattccaga taacctttta ggaacaaagg
    62341 agagaaaaac atggtacgtt acaaagcaat cattgcatac gacggaacaa attttaatgg
    62401 attccaaaaa cagccaaatg ggcgtactgt tcaagaagaa gtagaaaaaa cattacaaaa
    62461 aatggcaaat ggaaaagaaa tcacggtctt tggttcggga aggacagatg ccggagtaca
    62521 tgcgattggg caagtaatcc attttgatta tccagaggag cgtccgttag aacgaatgcg
    62581 tttcgcgcta gatacccagt caccagagga tattgctgta agacaagtag aaattgtttc
    62641 agaagacttc cacgcaagat atttggtcaa agaaaagacg tatcaatttc gagtggatat
    62701 agggaaacca cgcagtcctt ttcgacgcca ttatgcaagt tattttcctt accctcttga
    62761 tttggaaaaa attcagcggg cgcttcctga tttattaggg actcacgatt tcacctcttt
    62821 ttgtgcatca ggaagctcga tagaggataa agtacgtacg atctacgagg ctaagatgga
    62881 ggtaaatgaa acaaaagacg aattgttgtt tacatttagg ggaaatggct tcttgtataa
    62941 gatgatacgg atcttagtag gaacgctttt gaaaattggc aatggccgat tgcctgaaga
    63001 tagtatccca gatattattg cgaaaaaaga tcgtaatgca gcaggaccta cagcacatcc
    63061 tgaaggactt tatttgtatg aagtgaaata tgaataagag gttgtgacag aagtggtcag
    63121 cttcaagaaa taagaaggaa tttacgaaaa ttacttctca aaattttgca aaatttcggc
    63181 ttattttcga aggagctact tctggaacac cgtgaatcag aggttgtgaa aaagctgccc
    63241 tgcatcaagt aataagaaca accaaacaaa aatagctcgt catatttttc gtttggttgg
    63301 gcttattacc gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgaaatcagc
    63361 gttttgacct gagtattaga gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttg
    63421 ttgagctaat accgaaggtc agctgattga acaccgttta agaaagaggt cgtgagcctg
    63481 tcatttaact ctgagtcaca agtaacaatt tcaaaaaaca gcttctcatc tttgatgaat
    63541 atcgtgactt gtggacgagg cgttgataag tgaatcatct ttttgttacc tattttttct
    63601 gtaaccaaaa aacgatggaa cgttgttttg attgccctta atgaggacag tcggaacagg
    63661 tttgtcattt ttatatttaa atggcacaaa tttttctaat tatttgtcat ttagcgctga
    63721 aaatttttgc tatttatcta aaaaagtgat aactacttaa gatgaagcag aatatttacg
    63781 ccatacggca tacaaccgcg aaaaatataa aaaaaagaaa acgattgaac gcgtttttgc
    63841 agtcgcaaag gaaaagcatg gaatgcgcta catcaagtat cgagacttgg aaaacaatca
    63901 ggtgtatacg ctgattgttt ttgctgcaat gaatctgaaa aagttgtcca cttggcagtt
    63961 ggaacatatg tcttcatatc ttttattata caaaaatagc aaaagcacca gtctacactc
    64021 ttagtaaaga ggaaactgat ccttttgtct acattcttaa agtacttaaa ctaagtactt
    64081 tattttactc tttaggattg atacagtagc atctatccct ttattaataa tcttttattt
    64141 ttttaaataa agatgttgtc tccatcttca ggcactaaaa ctttttcgga aattcctttt
    64201 tctttattga aagactttaa ttcttctctt gacagtcccc aatggtttac agcttccata
    64261 tgaacggcaa taattgtgga atctggtatt gctttatgca attcatataa atcgtctttc
    64321 cccataataa gagattctcc aactaaaaaa tgattatctc cagcatttgc tactatgatt
    64381 tctggattat actgatcaat agtttgttta acagcttcat accaaactgt atctcctgta
    64441 aagtatagtg tcttctcagt cgaatgtttg aaaacaatac cgcaaacatt acctacataa
    64501 ttcaagattt ctcctctgcc atgtttgcct tttgttttaa ccaattgtat agattcaaaa
    64561 actgtgtctt ctcgtagtac ctccacattt ttaaaaccat atagtcgaat ttcattcgca
    64621 tcattttcat cttgcacaaa taattttatt tctttaggta ggacctcttt cgctatatcg
    64681 tcccaatgat ctagatgtaa atgtgttaca ataacagcat caataccgtt gataatatct
    64741 tcgactggca ttggcaaatc aactagagga ttcatttgat cttttcttgg tgatggaaaa
    64801 ggacctttcg aaataaatgg tggaagtgtt cctttttccg ctaacattgg atcaattaaa
    64861 aattttttac ctccatagtc taagatagct gttgcattac gaatgtgatg tatattcata
    64921 aacgttgtct cctttttgtt gatatgaaat atttttagta taattcaatt ccatacaata
    64981 aataaaccga acaaaaaaag tcttttacta tttttactta atttatgaaa ggttgtttac
    65041 catgttagac caaacagata taaatatcat tgaggaacta tcaaaaaata gtcgaatcac
    65101 aatgaaagaa cttggagaaa aagtacattt gactggaccc gctgtctcgg cgagagtgac
    65161 aaaactagag gaaagtggag ttattgaaaa ttatacagta aaattaaata tggaaaagct
    65221 agggttttcg attcacgctt ttttaattat aattacgcaa aatttaaatc ataaacccta
    65281 tttatcattt attaaaaatc atgaaaaatt cttgattaga aattataaga ttagtggagg
    65341 gggctgttat cttttggaat gtagatttac ttcaaaaaaa tcaatgaaca gctttttgga
    65401 acagcttaat gaatatgcga attataaatt atctattgtt atagattaat aataaaacta
    65461 gcagatggta aaaatactaa tatgcgagac acacattcaa ccataactat ataacttatc
    65521 aatttaaaac taaactgatg gaaacaagta aggcaaaaac atttatattt tgccctactt
    65581 atttttttaa ttaaattcat tgatgattca tatttagaaa attctatgaa ggccaaatga
    65641 gtatcctgtc acttttttag ataaatagca aaaattttca gcgttaaatg acaaataatt
    65701 agaaatattt gtgccattta aatataaaaa tgacaccaag tatatcatga acgcacaaaa
    65761 agaccaacag ggtataccct gttggtctaa a
//
LOCUS       DAIGWC010000005        60114 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.005, whole genome shotgun sequence.
ACCESSION   DAIGWC010000005 DAIGWC010000000
VERSION     DAIGWC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.005"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(233..1081)
                     /locus_tag="NOB74_000344"
     CDS             complement(233..1081)
                     /locus_tag="NOB74_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI1219556.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="NOB74_000345"
     CDS             complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="NOB74_000345"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HCI1219557.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3582..3761)
                     /locus_tag="NOB74_000346"
     CDS             complement(3582..3761)
                     /locus_tag="NOB74_000346"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HCI1219558.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="NOB74_000347"
     CDS             complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="NOB74_000347"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCI1219559.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5909..8188
                     /locus_tag="NOB74_000348"
     CDS             5909..8188
                     /locus_tag="NOB74_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1219560.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8281..8928)
                     /locus_tag="NOB74_000349"
     CDS             complement(8281..8928)
                     /locus_tag="NOB74_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219561.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9107..9826)
                     /locus_tag="NOB74_000350"
     CDS             complement(9107..9826)
                     /locus_tag="NOB74_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1219562.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9957..11108)
                     /locus_tag="NOB74_000351"
     CDS             complement(9957..11108)
                     /locus_tag="NOB74_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HCI1219563.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11325..12065)
                     /locus_tag="NOB74_000352"
     CDS             complement(11325..12065)
                     /locus_tag="NOB74_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1219564.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="NOB74_000353"
     CDS             complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="NOB74_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HCI1219565.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12449..13042)
                     /gene="yqeK"
                     /locus_tag="NOB74_000354"
     CDS             complement(12449..13042)
                     /gene="yqeK"
                     /locus_tag="NOB74_000354"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HCI1219566.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(13026..13676)
                     /locus_tag="NOB74_000355"
     CDS             complement(13026..13676)
                     /locus_tag="NOB74_000355"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HCI1219567.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="NOB74_000356"
     CDS             complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="NOB74_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HCI1219568.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="NOB74_000357"
     CDS             complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="NOB74_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HCI1219569.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15119..15646)
                     /locus_tag="NOB74_000358"
     CDS             complement(15119..15646)
                     /locus_tag="NOB74_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HCI1219570.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15826..16611)
                     /locus_tag="NOB74_000359"
     CDS             complement(15826..16611)
                     /locus_tag="NOB74_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HCI1219571.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16604..17473)
                     /locus_tag="NOB74_000360"
     CDS             complement(16604..17473)
                     /locus_tag="NOB74_000360"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HCI1219572.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17474..18853)
                     /locus_tag="NOB74_000361"
     CDS             complement(17474..18853)
                     /locus_tag="NOB74_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HCI1219573.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="NOB74_000362"
     CDS             complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="NOB74_000362"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCI1219574.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19305..19781)
                     /gene="accB"
                     /locus_tag="NOB74_000363"
     CDS             complement(19305..19781)
                     /gene="accB"
                     /locus_tag="NOB74_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HCI1219575.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="NOB74_000364"
     CDS             complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="NOB74_000364"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HCI1219576.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="NOB74_000365"
     CDS             complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="NOB74_000365"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HCI1219577.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21787..22704)
                     /gene="fabD"
                     /locus_tag="NOB74_000366"
     CDS             complement(21787..22704)
                     /gene="fabD"
                     /locus_tag="NOB74_000366"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCI1219578.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22811..23035)
                     /locus_tag="NOB74_000367"
     CDS             complement(22811..23035)
                     /locus_tag="NOB74_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCI1219579.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(23088..24050)
                     /locus_tag="NOB74_000368"
     CDS             complement(23088..24050)
                     /locus_tag="NOB74_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HCI1219580.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(24060..24500)
                     /locus_tag="NOB74_000369"
     CDS             complement(24060..24500)
                     /locus_tag="NOB74_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1219581.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24806..25771
                     /locus_tag="NOB74_000370"
     CDS             24806..25771
                     /locus_tag="NOB74_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCI1219582.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25828..26058)
                     /locus_tag="NOB74_000371"
     CDS             complement(25828..26058)
                     /locus_tag="NOB74_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HCI1219583.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(26144..27031)
                     /locus_tag="NOB74_000372"
     CDS             complement(26144..27031)
                     /locus_tag="NOB74_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCI1219584.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(27120..28343)
                     /locus_tag="NOB74_000373"
     CDS             complement(27120..28343)
                     /locus_tag="NOB74_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI1219585.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28360..29406)
                     /locus_tag="NOB74_000374"
     CDS             complement(28360..29406)
                     /locus_tag="NOB74_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI1219586.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            29644..30984
                     /locus_tag="NOB74_000375"
     CDS             29644..30984
                     /locus_tag="NOB74_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI1219587.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(31112..32839)
                     /gene="ptsP"
                     /locus_tag="NOB74_000376"
     CDS             complement(31112..32839)
                     /gene="ptsP"
                     /locus_tag="NOB74_000376"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HCI1219588.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(32839..33105)
                     /locus_tag="NOB74_000377"
     CDS             complement(32839..33105)
                     /locus_tag="NOB74_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HCI1219589.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            33584..35818
                     /locus_tag="NOB74_000378"
     CDS             33584..35818
                     /locus_tag="NOB74_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1219590.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILLI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            35966..36286
                     /locus_tag="NOB74_000379"
     CDS             35966..36286
                     /locus_tag="NOB74_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCI1219591.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(36491..36715)
                     /locus_tag="NOB74_000380"
     CDS             complement(36491..36715)
                     /locus_tag="NOB74_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HCI1219592.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(36913..38493)
                     /locus_tag="NOB74_000381"
     CDS             complement(36913..38493)
                     /locus_tag="NOB74_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HCI1219593.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(38894..40270)
                     /locus_tag="NOB74_000382"
     CDS             complement(38894..40270)
                     /locus_tag="NOB74_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCI1219594.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(40398..41516)
                     /locus_tag="NOB74_000383"
     CDS             complement(40398..41516)
                     /locus_tag="NOB74_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI1219595.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            41658..42092
                     /locus_tag="NOB74_000384"
     CDS             41658..42092
                     /locus_tag="NOB74_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1219596.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(42170..42703)
                     /locus_tag="NOB74_000385"
     CDS             complement(42170..42703)
                     /locus_tag="NOB74_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HCI1219597.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(42797..43975)
                     /gene="mutY"
                     /locus_tag="NOB74_000386"
     CDS             complement(42797..43975)
                     /gene="mutY"
                     /locus_tag="NOB74_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HCI1219598.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(43968..44765)
                     /gene="recX"
                     /locus_tag="NOB74_000387"
     CDS             complement(43968..44765)
                     /gene="recX"
                     /locus_tag="NOB74_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HCI1219599.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            44872..46254
                     /gene="rlmD"
                     /locus_tag="NOB74_000388"
     CDS             44872..46254
                     /gene="rlmD"
                     /locus_tag="NOB74_000388"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCI1219600.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(46428..47006)
                     /locus_tag="NOB74_000389"
     CDS             complement(46428..47006)
                     /locus_tag="NOB74_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HCI1219601.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            47328..47798
                     /locus_tag="NOB74_000390"
     CDS             47328..47798
                     /locus_tag="NOB74_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HCI1219602.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(47906..49132)
                     /locus_tag="NOB74_000391"
     CDS             complement(47906..49132)
                     /locus_tag="NOB74_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI1219603.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(49886..50086)
                     /locus_tag="NOB74_000392"
     CDS             complement(49886..50086)
                     /locus_tag="NOB74_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI1219604.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(50220..50828)
                     /locus_tag="NOB74_000393"
     CDS             complement(50220..50828)
                     /locus_tag="NOB74_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HCI1219605.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(50913..51383)
                     /locus_tag="NOB74_000394"
     CDS             complement(50913..51383)
                     /locus_tag="NOB74_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HCI1219606.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(51431..52345)
                     /locus_tag="NOB74_000395"
     CDS             complement(51431..52345)
                     /locus_tag="NOB74_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI1219607.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            52491..53294
                     /locus_tag="NOB74_000396"
     CDS             52491..53294
                     /locus_tag="NOB74_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HCI1219608.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            53472..54419
                     /locus_tag="NOB74_000397"
     CDS             53472..54419
                     /locus_tag="NOB74_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HCI1219609.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(54487..54780)
                     /locus_tag="NOB74_000398"
     CDS             complement(54487..54780)
                     /locus_tag="NOB74_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HCI1219610.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(54808..55473)
                     /locus_tag="NOB74_000399"
     CDS             complement(54808..55473)
                     /locus_tag="NOB74_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HCI1219611.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(55613..56245)
                     /locus_tag="NOB74_000400"
     CDS             complement(55613..56245)
                     /locus_tag="NOB74_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1219612.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(56252..57319)
                     /locus_tag="NOB74_000401"
     CDS             complement(56252..57319)
                     /locus_tag="NOB74_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI1219613.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(57316..58047)
                     /locus_tag="NOB74_000402"
     CDS             complement(57316..58047)
                     /locus_tag="NOB74_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HCI1219614.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(58216..58695)
                     /gene="greA"
                     /locus_tag="NOB74_000403"
     CDS             complement(58216..58695)
                     /gene="greA"
                     /locus_tag="NOB74_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HCI1219615.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(58831..60006)
                     /gene="mltG"
                     /locus_tag="NOB74_000404"
     CDS             complement(58831..60006)
                     /gene="mltG"
                     /locus_tag="NOB74_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HCI1219616.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
BASE COUNT        17384 a        12677 c        10189 g        19864 t
ORIGIN      
        1 aagaaaaaat gggcggagca agaaattctt tacctaattt caagataaaa tcaacttttt
       61 gtttcacagc aatcacttaa agttacatat ccaactattt ttttcattaa aaaataaact
      121 tatttttgaa aattatgttt tcttaagtcg tgaaacactt tgatggatca tttatttgtg
      181 gaaaactacg ttttgttatt ctaaaaaact tatataaaaa atagtaaggt ttttatttcg
      241 aatccataaa atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt
      301 cgtttttagc catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg
      361 aattagttgc cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat
      421 cggctatctt gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca
      481 tgcttttcgc cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa
      541 gccaaagcac tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt
      601 tttcaaaaat gattggctta ccgacacgag accatttttg cagaatatct tctactacta
      661 aagaagaggc gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga
      721 ctttttggat cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat
      781 tgttaccaag tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac
      841 cttcatcgat tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt
      901 gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg
      961 ctaattcatt agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca
     1021 actttttttc tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca
     1081 taagttcctc caccctttta atgatagtct atgtaagtat accatatcag acccttattc
     1141 acggtcgtat actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca
     1201 tcaatcccac agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt
     1261 cggattgctt tctatctact acttttttac aggaaattta cctattagtt ttctctgctg
     1321 taatttttga cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt
     1381 tctttacttc cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca
     1441 actaattggt aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca
     1501 ttacgatcat caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa
     1561 gcataatcgc catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac
     1621 catgttggaa aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta
     1681 gaaacaattc cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca
     1741 tatgtcaaat caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct
     1801 tctgtaccaa gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg
     1861 ccttctgctt caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg
     1921 gctttttccc acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag
     1981 ctcaagcgga aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca
     2041 agcgtacgtt taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc
     2101 aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc
     2161 atcattccta attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg
     2221 tagaccatca tgtgatgagg gcagttcatt gggcgaagaa caagcatttc gccatctccc
     2281 atatccattg gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac
     2341 aactcaacat ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg
     2401 tctacgatat aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc
     2461 aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga
     2521 tggtctcttt cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca
     2581 aaaaaggctg tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa
     2641 gcacctgcca ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt
     2701 ccacgacaca aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc
     2761 aattcactaa tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt
     2821 tttgaaagaa cacggcgttc gatcggcaga ttttctttga cgattttcat catttctgct
     2881 tcgattgccg gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa
     2941 aaccctgaat cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg
     3001 gcttgggcca tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct
     3061 ggtgtgatga tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt
     3121 ccgttcactt taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt
     3181 gccaatgttg ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt
     3241 atcataatag tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa
     3301 aaaaatccta gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa
     3361 tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca
     3421 agggtttcga aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc
     3481 ctctcttatc gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat
     3541 ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca
     3601 tttacaccgt atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt
     3661 gcctgcgtgt ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc
     3721 ggactgcgac cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct
     3781 gatcgttctt ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg
     3841 aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac
     3901 ttcttgcaaa acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa
     3961 aaaaatacaa ataaagatgc caatcagtac agactgtttc gctattctca tcgtatctct
     4021 tgaaatcact actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc
     4081 actttcacta gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc
     4141 aagtgctggt gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg
     4201 gatactttct aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa
     4261 ttggactttt tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa
     4321 atttttcaca tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg
     4381 atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt
     4441 ggacgtttct atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt
     4501 attgactact gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag
     4561 ttggctgttt ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc
     4621 tgcactagct gcatacagaa gtagctcttc tttttttatt ccattgactg gctgaatcgc
     4681 ctctacttcc aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt
     4741 acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg
     4801 gctcattcct gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac
     4861 taccagtacc tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat
     4921 caaataagca atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc
     4981 aggcttttct tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc
     5041 acgtttttca gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg
     5101 atctccaggt ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga
     5161 agattctcct ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa
     5221 ctggtcatca atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg
     5281 atgggcaatt cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt
     5341 cgcgtaatcc tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca
     5401 gtattctttg acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata
     5461 tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc
     5521 agtaaatgcg acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa
     5581 agctatccca ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc
     5641 tcctctttta tgtgacttag agaggttagt aataaatttc cagctgcctc tttcatctta
     5701 agcatagtcc ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac
     5761 tatcagcgtt tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt
     5821 ttcgattcat cagttaaaaa gtaccttttt tcgaaaaact atgctatact tttaattcgt
     5881 tatttacggc ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt
     5941 ggatgaaacg atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga
     6001 attgactcag gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg
     6061 ttccaatgaa gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct
     6121 tttgaaatac catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa
     6181 agatagtcct tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata
     6241 tctaggtatc gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgcgc
     6301 accaattgcc aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaac
     6361 agatagaata gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggacgtat
     6421 tttatctatg gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga
     6481 tgaatcatca agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc
     6541 aatcattcgg gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa
     6601 gacatccgct ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga
     6661 ggctgaaaac gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt
     6721 attgccttca ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca
     6781 gctgctgcca gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg
     6841 ggaaaaagat ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg
     6901 ctatatccaa ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg
     6961 tacgatccta tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattacc
     7021 tttacatcat agactttctc tattacaaac gaagctcctg aaaaaattag gcggtctgca
     7081 aaaagacgaa acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact
     7141 atacgcaaca gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa
     7201 actggccaac caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta
     7261 tcaatttgtc aatataacga aacaatatct ccactttcta caaactgtgc cactttctct
     7321 tctaacacga cataaaatca gcgagaccag gtggcaggaa catttgacaa ctgttcgtac
     7381 acacttgcgt caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg
     7441 ccgaacatat ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca
     7501 ggatttcgca ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac
     7561 tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga
     7621 agaccttttc gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac
     7681 aaaagaaatc actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac
     7741 agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa
     7801 ttggttagca gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat
     7861 catagctaaa acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa
     7921 acaacaagtc cagctgattt taaatgagag tgactttatg aagcgttcca ttattttact
     7981 tccagccttt ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc
     8041 agaacatttt tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat
     8101 gcatgaattg acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat
     8161 ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc
     8221 agttgtcttt ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat
     8281 ttattctata tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat
     8341 cattttcagt tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc
     8401 aatcccgcca ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga
     8461 ttggaaattg ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag
     8521 gtatgcacta tcgatcactt tatttttttt cgtgtctatc ttctcatttc tttcgataag
     8581 aattttttca ggacgatgtt tcaagctcca ctctaatagt agaaagaaag cctccatccg
     8641 atactcttct tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag
     8701 ataattttgt ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt
     8761 cagataccct gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta
     8821 tttttgcgct aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta
     8881 accgcttaag atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt
     8941 ccatcttcca catacttcat atcatttcac atgatactta tgctctcatc ataccacagg
     9001 ttgaattaga aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt
     9061 cttgcttttc gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg
     9121 ccacattatg gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt
     9181 caaatgtttc ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct
     9241 cagcgattga aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat
     9301 ccgctacttc accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga
     9361 tgtctttttc cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga
     9421 ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt
     9481 tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa
     9541 caatcaccat tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat
     9601 ctcctgcacc ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag
     9661 ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg
     9721 attttgctgc cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat
     9781 ctttagcagt tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct
     9841 ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg
     9901 attctgtgaa gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat
     9961 actcggattg ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt
    10021 tgatcacttc taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa
    10081 atagaaatct cttttttttc ttttaagaat cttcttccag catcggtaaa tccaagtagt
    10141 cgaagataat ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca
    10201 taacaagata atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca
    10261 aaatcctcaa aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg
    10321 gtcatctgat agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa
    10381 tacggccaat aagattccca agtctgcagc gaacaagttg aaagatcttc ttctgtctga
    10441 ggcggcacaa gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca
    10501 ctggctatcc tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc
    10561 ggatgtaatt ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag
    10621 atatgatttg gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca
    10681 gtcatttttt gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc
    10741 ctatcttgat tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct
    10801 tctgttccaa aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta
    10861 gcaaaatagt cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca
    10921 ccattttgta aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctctt
    10981 tgcaaaaaat tcccgctcat tacagcaatg acgacctctg ctcctgttat ttttcgtgcc
    11041 atttccacat gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag
    11101 cttttcatgc gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa
    11161 aaggcaaaaa tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt
    11221 ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg
    11281 ttgaagattt attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct
    11341 acaaagaacc agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct
    11401 tcgactttcg aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta
    11461 cgctcttgat gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg
    11521 aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa
    11581 aaagcaaaat tatccccttg ataatgatag ctatattctg gaaaaacctc atctacttga
    11641 taggtggagt gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca
    11701 tcaaacactt gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag
    11761 gtaattgcct gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg
    11821 atcgatgcgt cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg
    11881 tctaaccctg tcactttata tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg
    11941 catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac
    12001 cattgctgat aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa
    12061 gccatatgtt aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt
    12121 tccagattat agaaatttcg ttctggcgca tggaaaacat gtacgatcac atctccaaga
    12181 tcgatcaata cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt
    12241 tcttcttctt tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct
    12301 gaacagatca tgaaataatc tgccaacaag gaaacatttc gaacgtctaa agcgataatg
    12361 tcttctgccc gttttgaatc tgctgcttca atcgcaattt ttaattgttc tttactatct
    12421 atgatgattt cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt
    12481 cgattgtttt tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg
    12541 tttcaaatgc tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc
    12601 caggaaaatc tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac
    12661 tcatcttagc agccccagtc gtatgcaccc ggattgcatg aagaatctct gcatcggtga
    12721 ttcctaattc ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat
    12781 aattcaataa ctccggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg
    12841 gtcgttcttt tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac
    12901 cgtatttttt ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt
    12961 gttcgctcat tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt
    13021 cattactata gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct
    13081 ggaacaaggt agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg
    13141 atgtcgatct caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct
    13201 ggtcgacgta tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt
    13261 ggcaaatatt ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt
    13321 tgcgtcaatt ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc
    13381 gtttcaatct gcaaaaaagg attgtcttcc accgctaatt ccaacatgtt gagtcgatgt
    13441 tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat
    13501 acgcggtcaa gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga
    13561 acgggattga atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc
    13621 atttcttcag gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc
    13681 actccttata ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt
    13741 ttgtataata caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct
    13801 aatacttgag ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc
    13861 agttctcttt tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct
    13921 tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt
    13981 tttcctctta aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca
    14041 tctacaccct ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct
    14101 agaccggcaa aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc
    14161 ggaaatgcct cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga
    14221 taaaattcgt ctgctttttc cagtttcgtt cgatgaatat ttacatcatt tgacacataa
    14281 gcaataaatg aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa
    14341 agtgtttgcc cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg
    14401 atccgcaaat cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt
    14461 gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct
    14521 ggaaactgcg aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg
    14581 ataagcgtcg attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg
    14641 tattcttcga ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat
    14701 aatacatcta ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat
    14761 ttagtttttt tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga
    14821 ttgtcaccga caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc
    14881 accacattga cgatcaatgc atctttttgc cctaattcat tcagtaagcg caaaaagtcg
    14941 tcatccgtca atgagacatc ttgggtctca ttataatggc gtaatctgaa acaacgctga
    15001 caatagactt ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat
    15061 tcaccgggtt tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc
    15121 attcgattcc acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc
    15181 ttttttccca aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta
    15241 caaggatgct acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc
    15301 ctaccattac tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc
    15361 ttgctaaagg tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg
    15421 cgacacgttt tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt
    15481 ctaaaatcca agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat
    15541 tgtctaaatc ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct
    15601 gatagatggc ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc
    15661 tgcaaaaaat gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc
    15721 aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac
    15781 caaaaataaa gattgatcac agaaaaattt agaaacaaaa aacaactaat attggcggaa
    15841 cctcttgtat cgtttttcca gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct
    15901 ttcaatcaac gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt
    15961 gaacgtttca ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat
    16021 tttcatcaac tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa
    16081 tccttctgga gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa
    16141 acctagagca agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac
    16201 ctttaaatca gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc
    16261 tgctcctaca ccgcaatatg cacctgctgt attgatcaag gtaatcaccg gtctattgaa
    16321 cttttccgct tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc
    16381 aaaatttctg cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac
    16441 cggtttgcca tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaataaacg
    16501 atcaccatgg cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca
    16561 tcgttcttta gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc
    16621 atcctttctg tgtatgcaat tcaagaagcg tatggatttt ctgtttcaat tccatgcggg
    16681 gaacaatctg atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg
    16741 gaagttcctg cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt
    16801 ggggttctgc tagaataata tcgccttcca ttgcaaaact ggcagttact cctccggtcg
    16861 tcgggtccgt taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag
    16921 cagagatttt tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg
    16981 aagctgtgaa caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga
    17041 tcttttctcc gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa
    17101 taatgaaggg aatcccctga atggttgctt taccagtgag gactgcttca tgaagtcctg
    17161 ttttatcttg cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg
    17221 ttacaagatc cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct
    17281 gccatgcacc gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt
    17341 ctttcgtata aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag
    17401 atggcgagtt agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct
    17461 taaacagagc catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt
    17521 cttcttgtaa aaatgctgtg ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat
    17581 ccatctgaaa ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct
    17641 gcatcttcat taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg
    17701 aatcataata tggcgggatc gtatatcccg ggtaaactgc actgtctact cgcagtccca
    17761 tcccacctgc tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag
    17821 caggattttc tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt
    17881 gacacacatt caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc
    17941 ctgtgaccat ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat
    18001 aaaaatcgcc ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg
    18061 ctttagctgc tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta
    18121 cagaaggaga ttcttccagt actttttgat tgttgcgttg taaagaacaa tctcgctcgc
    18181 ctaaatgaat gacatgacca aatcgatcac ctaagatctg aacttctata tggcgagcag
    18241 gataaatgat tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct
    18301 gagctgaaga aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc
    18361 cgccaccacc tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca
    18421 atgcttcttc tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt
    18481 cttgcatcaa ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag
    18541 gaccaataaa tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata
    18601 aaaaaccaaa tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt
    18661 cctgaacatt cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg
    18721 ctaactgtgt atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc
    18781 ctagttcgcg gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata
    18841 ctttagaaaa catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt
    18901 ttaccgtcta ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc
    18961 tcaacttcaa ggtataaggt atctcccggt gtaactttct tacggaattt tgctttgtcc
    19021 aatccgccga aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct
    19081 cctgcttgag ccattgcttc aacaatcaat acccctggca taacaggttc ttctggaaaa
    19141 tgtccttgaa aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct
    19201 tcaaccattt cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct
    19261 tttatttctt gtatgttcat tgttttccct ctttcctgct ttgcttattt ttgctgaatc
    19321 ctaaagagtg gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc
    19381 actccgtcgg cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata
    19441 acttctcctt tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgctggt
    19501 tgcagataaa cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat
    19561 tctttttctt tcattatttc tggagcagtt gttgcttgtt caggtatgac attgactggc
    19621 tccgaaactg gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt
    19681 ttattcatat acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga
    19741 tcaaattgac tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt
    19801 tcatgcacag aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa
    19861 aacttgcagg tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt
    19921 ctacattgat cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt
    19981 cgatcccgcc ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag
    20041 tatctctgaa attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg
    20101 ctggtgtact tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt
    20161 cttccatcgc aagcttcatt gctttagatg caccagaacc atctggagta ggagctgtca
    20221 tatggtaagc gtcacagttt gcaccgtatc caacgatttc tccatagatt ttggcaccgc
    20281 gagcttgtgc atgttctaaa gattcaagaa ctagaacgcc tgctccttca cccatcacaa
    20341 aaccattccg attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga
    20401 gtgctgttaa agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc
    20461 cagcaagaat gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat
    20521 tcgttccgct agcacaagct gttacgatag ctgtacaaat accttttgca cctacacgca
    20581 aagcaatatt tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc
    20641 gttttgcacc tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga
    20701 tcccagatcc gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc
    20761 tcatctccat tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt
    20821 tgctatcttt tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg
    20881 taatccctgt ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt
    20941 ttaagctatt caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag
    21001 taattaccac tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc
    21061 catcgacatt gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt
    21121 gtgcaatatc ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct
    21181 tgactttgtc tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat
    21241 tacatgtaat gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc
    21301 cagctttact agctgcataa tttgcttgac caatatttcc aatcaaccca gatacactag
    21361 agagattaat gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca
    21421 tattgaaggt tccaatcaaa ttgatatcca gacatttttt gaaatcttct gcatccattc
    21481 gcatcacaag tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa
    21541 gcttttcttc tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg
    21601 aaactcctac gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct
    21661 ctccgcgacc attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt
    21721 tgccgattcc tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt
    21781 tcctccttat agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac
    21841 tggtattgtt ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc
    21901 gatgacttgt tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg
    21961 ttgcatgact tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt
    22021 tgtgttgctt atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc
    22081 cagttttttt gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg
    22141 gatcattctt ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc
    22201 ttcgccacca atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta
    22261 cttgctagct tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac
    22321 cattttcccg cttccagctg gggcagcttc tgtcatataa gcgcctcttt ttgctactaa
    22381 cgcaactgct tcagtgaagg atagcgcatt actagctact aatgccgaat attctcctaa
    22441 actcagtcct aaagctgcat ctgggatgat tccatgctcc ttcaataagc gataatacgc
    22501 gatgctgact gttagaatag ctggctgtgt atattgcgtc tgatccaaac gttcattttc
    22561 tgtaaagcaa agttcagcca tatcgtagcc gagaatctca cttgcttcat caaatgtctg
    22621 ctttacaacg gcttcttcat ataaatcttt tcccatacct tgatattgtg caccttggcc
    22681 actaaataag aatgctgttt tcatgttttt ctccaatata tccagaatat atgtttgatt
    22741 cttcctattc aaaaaggccg agacattcct atttcaggaa atgtcccagc ccccaaccta
    22801 attttaatga ttatgcagtt tgtttttcta cgtaagtcac taaatcttga accgttttga
    22861 ttccgtcttc tgtttcgatt ttcacgtcaa attcatcttc aatttcattg atgatttgga
    22921 ataaatccaa gctgtcagct tctaagtctt cttggatgtc agtagtcaat ttgatttctt
    22981 cagtttcttt tcctaattct tctgcgatga tttcttgaat tttttcgaat accataataa
    23041 tatattcctc cgatattgtt tgctttttat ttttataatt taacagtcta caactccatg
    23101 agaatacttc cccatgttaa acctccgcca tagcctgtaa atattacttt ctgctgtttt
    23161 cctaaggtga tctttccact agaaactgct tcatccaata agatagggat gcttgcagca
    23221 gatgtattcc catatttatc catattggtc aggaactttt cttgcggcat ctttactttt
    23281 cgggcaattt tctcaataat tctgaggttt gcctgatgca aaagcagata atcaactggt
    23341 ttgtctttca tgacttcttg gatattgttt gcaacgtctc gtacggcaaa atcaaaaata
    23401 tctctgccag tcatttgcaa ataatacgaa ccttctgaat cttctgaata gaacggattt
    23461 ttattttgct ggtagccagc ggtcaatgag ctacttctgg taccgtcagc tgctaatttt
    23521 tctttcagca attttttctg tggattcgct tctaagagaa tcccacctgc tccatcgcca
    23581 aacaacacag cagtcgtacg atcagaccaa tcgattagct tagatagtgt ttcaccacca
    23641 atcaccagtc ccttagttga gccgcagcgg atcatttttt cagccatgct taacgcataa
    23701 acaaatcctg agcacgcagc actgatatca aaagcgatag catgagttgc tcccaatttc
    23761 ccttgtactt gtgctgctac agatggtgtc gtgtaatcgg gcgacattgt tgctactaaa
    23821 ataaaatcca aatctttagg gtttagattt ttctgtttta tcaatttttc cgccactaaa
    23881 atgcataaat cagaagtctc ctgatttgtt acacatcttc gttcacgaat acccgtcctt
    23941 gacgaaatcc attcatcaga ggtatccatc atcttggaaa gatcattatt agtaataatc
    24001 ttttcaggaa ggacgctggc tgttgcagta atcattccaa attgttccat taaatatcct
    24061 cacttatagt cttgcaagaa gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt
    24121 tcctccgtag ccattccgtc taagatgttc ttgaccattt cacgatgaaa atgctgatgg
    24181 acccgaaata gtaactttcc ttttttcgtt agtcccaact ttacaacgcg gcggtcatct
    24241 tcactgcgga tacgttcgac atagcctttt tttactaact tgttaatagc agtggtcaag
    24301 gtcccaacag taattgatag ttctttggct acttctgaag ttgttttttt cttgtacatc
    24361 ccgattgcct cgatcgtgtg catctctgtg attgacagat ctttgaattg agattttttc
    24421 agctcagact cttcgattgt caaaatatca ttgaagacac taacaagata atcatttact
    24481 gtttttaaat ctggttccat gttccaccgt ccactaatta gtttgattat caaatctttt
    24541 gatgttcaaa ctatatctta acttttttca aaatgcaacc ttaaaagatc atttttttac
    24601 tatatgagct ttttttaaga ttttactcat ttaaaacaac tgataaatca gcatttataa
    24661 tttcttttat tagaaaaatc atctatctca catattttga ttatcaaagt attttctgtg
    24721 aacagaacta tagaattccc taaaacttgt ccattatttc aaaatttgtt atagtctttt
    24781 tattcaaagc gtaaaaggag atcctatgtt aaaagaaaaa atgaaaactc tccccatgct
    24841 gccgggtgtc tatcttatga aagaccgaga tggtaaggtc atctatgttg gtaaagcaaa
    24901 acggctcaaa aatagagtaa gcagctattt tcatcagaat aaacagcatt caaaaaaagt
    24961 attacgtatg attcatcata taacagattt tgatttcgtc gtagtagaca cggaattaga
    25021 tgctttattg ctcgagtgtc aattgatcca acattaccgt cctttttata accgacaaat
    25081 gaattatttc agtaattata attatgtaca tattaccaat aagggatttg tattaacaga
    25141 tactcctacg gctcgaacat acgggccttt tcgtctctat aaaaaaatgc cgtctatttt
    25201 gcgtataatg gaagaaactt atcaaatgcc ttggttgtct gaaattagtt tgttagcttt
    25261 gcgagtccag cttcctgacc tacaggaaat gacttttgaa cagaaaaaaa aggaactcca
    25321 agggctgttt caaggccgaa ataaaaagct actgacttac ttgaaaaaaa gacaacaaca
    25381 tttcatctat cagttgaatt tcgaaaaagc cggtatgctt caaaaagata tcgaattagt
    25441 tacttatttt attagacgga tccaggaaca aaagcagttt ttaagaacac catcgctcac
    25501 cttcagcatg ccattagcag cagatgagag tcagaaaaag cactacctcg tttgttatgg
    25561 tcaacttgca gaaacaatga ttacctctgg tgacgtttct cctgacttct attatgaaaa
    25621 gaaagaagct catttatctt tgaaacgtca attgtcaaaa gaagaaatcg atcctgtaca
    25681 aatcttgatc agttaccgca aaaaattaga aaaagaacag tttgaaattg aactgttaaa
    25741 caaaaaagaa gctgaaaagc aactaaatta gttgcttctc ggcttctttt aggcatcttc
    25801 aacttcaaat gtcaattatc ctaaaattta ttggattaag tcatagattt ccatcgctac
    25861 gatatcgata ttatcaaatt cgtattgctg atgagtatct gtttcagtta attcaaatgt
    25921 atcggtcgct ttatcataag ttactgtaca cttctctacg ccttcttttt caaaacggcg
    25981 aacttgcagt tcattatctg ctgactcgac catagcctcc agtcgtttta tgattgcgac
    26041 taattgtgaa tgtgtcatcg gaggtcctcc ttttcttatt tctgttatat tgtatcaaaa
    26101 gcatagccta cttgcattga ttttctctaa aaaaactcgt tttttatgat tttttttctg
    26161 gtatttttcc ttcaggccac caaagtttga tcaaagcttg ggttccgtca ttctcaaaac
    26221 ctttatctgc caactcttca tatagtttca atgcttgggt agttgctggc aatacaagat
    26281 ccattttttc tgcttcttct aatgcaatct ttaaatcttt gataaaatgt ttgacaaaaa
    26341 aaccaggtgt gtaatcttct tttaaaatac gaggagaata attgcttaaa gaccagttag
    26401 ctgcacttcc acctgaaagc gtctcaatca ctttctttaa atcaagtccg tttttttgtg
    26461 catagacaag catttccgtc attcctgtca tcgtacctgc aatcatgatc tgattagcca
    26521 tttttgtatg ctgacctttc ccagcagaac catgcaatgt aaatgtcgta ccaaattctt
    26581 tgaataaagg cagtacttga tcataaacgg cttcttctcc accgaccatg atcgtcagtg
    26641 taccattctt tgctcctaag tcaccaccgg ataccggtgc atctaacgca tctgcgcctt
    26701 tttcttttgc tgtttttgca attttttctg ccaggcttgg tgtacttgta gtcaaatcaa
    26761 ctaaaatatg tcctgagata tctgcagaaa aaatccccga ctgtccatag tagatttctt
    26821 ctacatcttt ggggtaacct accattgtaa agagaatatt actttgttct gctaccgctt
    26881 ttggtgtatc tgcccagata gctccttctg ttactaaagg atcagctttt gcttttgtcc
    26941 gattatagac agctacttcg tgtcctgctt ctagtagatg gcgtgcgaca gcacttccca
    27001 tgacgcctgt tccgataaaa ccaagtttca ttttttcgac ctcctaaaaa tcaaaaatcc
    27061 ttgcttctat gctagtatac gctagaaaca aggatttttt cataaaaaat gtttgaattt
    27121 tatcttttaa atgaatttaa ttttattttg attcgttcaa tcgagtcttc ttcttctttt
    27181 cttcgcatct cttcttcatg ataaacaacc atgtcttgat aaaattcgat catagcttcg
    27241 ccgaaatgtg tagatgaaat atcataaagt ttagcttcta aaacttttgg atctttagga
    27301 acttcactgg aaatataatc aataagtgct ggtgcaaagt cttcgtcggt ttcaaaagtt
    27361 ttccctaatg aaggatgatc gaacaatcgg ttcaaataag catttccttc cacgacacaa
    27421 ggtgttccgg ctgccatcgc ttctgtataa gtaagccctt gtgtttctga agtagaagca
    27481 ctgacaaaat aatctgccgc tttataataa agtgctacat cattgttgtc cacttctcct
    27541 gtgaactgca caaattcttc taactgcagt tctgagatca attcctctaa ctcttctaca
    27601 taaggtcctt ttcctacgat aactaatctg gcgttaggat aagcggagat gacctgagga
    27661 aacccattaa tcaaggcttg gatatttttc tcataagaaa tcctgcttaa agaaagaatc
    27721 atcaaatggt tttcctgaag acctagtgac tcccttaatt tgctgatatc ctgctgagtg
    27781 atatcagaac gtttgaattt ttcaatgtcg ataccagtag gaatcacgcg aagcggtgct
    27841 attacaccat agctgcgtaa tgtatcaata acacgttcac ttggacaaac tacacctgtc
    27901 gtatgatttg caaataatct agacaagtat tttacatggg attgcctgat cacttttcct
    27961 ttaccgatat aatgaaggta gtcttcatac atcgtatggt aagtatggat cagaggtatt
    28021 ttcaacttct tagctaccat cttcccaagt atccctgctc cgaattctgt atgggtatga
    28081 ataagatcta gttctagttc tttggcaacc aaataagcat accacatgcc tctaacaaca
    28141 actcttcgat ccttgaaaga aataaatggt acacttggca ttcgaatcac atctttttcc
    28201 aacttatccg cattaggatc ggtcgttgta aaaatataga cttcatgccc atgtctttct
    28261 aattcttgtt ttaatgtttt gatcgatgta gcaactccgc tgacttgcgg aaagtaggta
    28321 tcggtaaaaa agccgatttt catgtttttc gcctccaaac tagtccttga cctgatttac
    28381 tttttttaat ttgctagaga ctttttcatt cagtacactt tcgtatacat ttttaagttc
    28441 ttcaccgatt ttattgatac ttcgctcttt tgctgtttga taaccggctt gtgtcgtact
    28501 cggtagttct tgattggtaa tctgttggat cagtcggata aattcttcgt ttgtcttccc
    28561 catatagcag ttcttgctat cttctaacca gccattatac actggaatat ctcgaacaag
    28621 tacgttttgt ttgcttgcta aagcttctaa aacaacgatc ccttctgtct cttcataaga
    28681 agggaaaaag aatagatctg cacctgaata cgcaccttct atgatctctc cacgaatgta
    28741 accaggaaac aggacatttt caggatgatc ttcttttaca attttccgga tgttccgagg
    28801 aatcgagtac atgggaacat gaccaaacca aataaatgtg tattcgggca tcttcttagc
    28861 aatttctacg aaatcaatga ttcctttacg ttcgaaaaac aaaccgacac aaatgattac
    28921 tttttgatcc ggagacagtt tgaaatattc tctgaacttt tgttctttca ttggatcagg
    28981 gtgatatttc tctaagtcga tcccattgga aatagcttga atcggcacac ggataccata
    29041 gctttccaac aactgttttg aataaggtgt tggcgtgatc agatagtccg ctttttggta
    29101 caatcctacc agatattttt ttacgatagg agaaagctgg ttcgatctga taaaggaatt
    29161 tcggaaatct tcctctgtag aatgcgcatg atagacaact ttttttcctt ctcttctggc
    29221 tttattgacc atattatgac tattgattcc gtatgtattg atgtgcagga tgtcataatc
    29281 ttctttttca tctagtgtat aagagatacc gacttccgtc agagcacgtt tttgatgatc
    29341 aagcgcacgc ccgattccag attttgcaag catcttttca ctttcaaaat ataataatac
    29401 cttcacctta cgtccccctt cacttatata gtataacata gcctacaaac tgtcactcaa
    29461 acttaagccc tatttttgtc tattcttact gacaaaaacg ttttcttaaa aggatctata
    29521 atatctagtg ttggtgacgc cttctgttgc caatactttt tcttttttct aataaacgca
    29581 aacagacacc ttgaaatcct ttagaataaa gtcgacgaaa accattcaaa ggagtgtttc
    29641 aagatgtcct attcagagtt taccaaagag ttactagata ttctagacct aaatcttacc
    29701 tttcatgaag atgcctttcg caaagagcgc attaatgacg aaacatgttt tgtttttgat
    29761 ggcacattga cctatcaacc agaggaatgc ttccattgcc actatcaaaa taagcaaacg
    29821 atcattaaat ggggctggaa aaaagtatcc atcttattga atgatgtcag taactacaag
    29881 accattgtgc ggattaacaa acagcgcttc aaatgtaaac actgtggaaa gactttttta
    29941 gcagaagatt cagttagcga tcgtcgctgc tccattgccc gcagagtcaa acaagccatt
    30001 cttgagctat taagtgagcc tatttctatg tctttgattg cacgtatgaa gcacatttct
    30061 ccgaccactg tcattcgaat acttcgcagc cttcggccta aaaccgtttc tttgaaccag
    30121 ccgttaccag aagtggtgtg tttcgatgaa ttcaaatcgg tgaaaaacgt ctcgggagcc
    30181 atgagctttg tcatgatgga cggcaagacc catcaactga ttgatattgt ggaaaatcgg
    30241 caactcaatc ctttacgcga ctatttcttg cgctacccta gaaaagtccg tgaacaagta
    30301 cgtctagtgg tttcagattt ctatacaccc tatcgcacat tggtgaaaga gtgttttccg
    30361 aatgcccgaa tcgtcgccga tcgctttcat attagccaac acatcggtcg ggcctttacc
    30421 aaccaccgaa ttcaagtaat gaagaccttt aaaaaagggg atcgtcggtc gaagcactta
    30481 aagaaatact ggagactact tcaaaagaat gcgtgggaat tgaatggtca gcatcgctac
    30541 tggcgtccgt catttcgaga tcatctgaca gaagcggaga tagtcgatcg gctattatat
    30601 tatgatgact ccttaaagcg aggctacgaa gtctaccagg tttttctttc cgctatcaga
    30661 agacaagatg ttcctgaatt cgtcgcgctc ctaaaagaag actacaagga gttgccagag
    30721 cactatcaac cagtgttcac gaccttcaag aaatatcgaa cagaaatcaa acgagcgttg
    30781 cgagttccct attccaacgg ccctatagaa tgtttgaaca accatatcaa agtactaaaa
    30841 cgaattgcct atggctttag aaactttcaa aactaccgag aacgaatctt tttatatcga
    30901 ggaaaatatt tcaagaaaac taagaacact acccaactga ctaaagccag aacaacaaca
    30961 cggctagaca agatagctgt ctagccgtgt gagtatctcg attattctat tgaatttctt
    31021 caccaacact cattgacgaa gagcctctta aaaaagaaca aaaaaactgg cgtagctctt
    31081 ttacaagcca caccagcttt tgatacgttg tttattttac atattcatga acaagttcaa
    31141 cgacttcttc catcatatcg cattctttca atgcacgatc agcaagttca gccattttcg
    31201 ctgtgtccaa gcgtttcatt aaactacgcg ttttaagaat agatgtcgca ctcattgaga
    31261 actcatctag acccatacct actagcaatg gaacagctgt ttgatctcca gccatttctc
    31321 cacacatacc tgcccatttt ccttcagcgt gtgctgcatc aattacattt ttgatcaaac
    31381 gtaaaattga tgggttatat ggttggtaca agtaagaaac gcgttcgttc atacggtctg
    31441 ctgccattgt gtattgaatc aaatcgttcg tacctacaga gaagaaatct acttcttttg
    31501 caaacttgtc tgctaagact gctgctgctg gaatctcgat catgatgccg acttggatcg
    31561 tatcagatac ttccttgcct tcacttatca atttttgttt ttcttcttca aagatcgctt
    31621 ttgctgcgcg gaattctttg agtgtagcta ccatagggaa catgatacgt aaattaccat
    31681 gaacagatgc acgaagcaat gcacgcattt gtgtacggaa catttcgtcg ccttgttcag
    31741 ataaactgat acgcaatgca cgatatccta agaatggatt catttcatga ggtaattgca
    31801 gatatggtag ttctttatct ccaccgatgt ccattgtacg aacaactaca ggttttcctt
    31861 ccataccttc taatacagct ttgtaagctt catattggtc atcttctgtt gggaagtctg
    31921 gagaatccat atacaggaat tcagtacggt acagaccaac tgcttctcca ccattattat
    31981 ggacaccaac tagatctttt ggtgttccga tgtttgcagc taattcaaaa tgcttgccgt
    32041 cagctgtgac agtttctgca ttttttaatt tttcccattc tgctttttgt gctgcgtaat
    32101 ctgcacctgc tttttcaaat tcagcttttt gttcatctgt aggatcgatg attacatcgc
    32161 cttcgatccc gttgacagcc aaaatatcgc cttctttgac tttagcagta atttcttttg
    32221 tcccaacgat tgctggaatt tctaaagaac gtgccatgat agcagaatgt gaagtacgtc
    32281 caccaatgtc tgttacaaac gcttttacaa aattgcgatc taattgtgct gtatcacttg
    32341 gagtcaagtc atgtgcaaca acgaccactt cttcgttgat cattgatgga tttggtaaag
    32401 taacgcctaa taagtgcgct aaaatacgtt tagcaacgtc acgaatatct gcagcacgct
    32461 cttgcatata agcattatct tccattgctt cgaacatacc gatatacata tccgttactt
    32521 cttttagcgc tgattcagca tttacgctgt tgtctttaat attttgcttg atttgaccta
    32581 ccatttctgg atctgaaaga accatcaaat gggcatcaaa tacttgcgct tctgcttcac
    32641 ctaagctttg cgctgctttt tcacgaattt gctgcaattc ttcagtagat ttagctaatg
    32701 cagcatccaa acgagcttct tcagccgcag tatcttctac tgttgcctta ctgaatgtta
    32761 aatccggttg aactagcagg taagcttttg caacggctac accgtcacta gcggcaatcc
    32821 cttttagcat ttcaaccatt attcagataa gccttctttc ttcattgttt caacgattgc
    32881 tgccattgca tcagcttcgt cagcaccttc tgcagtaata gtaacatcag aaccttgacc
    32941 tacacctaaa gacataacgc ccatgattga tttcaagttt actgatttac ctttatactc
    33001 taagtttaca tcagagttaa atttgcttgc tgtttgtact aatagtgtag ctggacgagc
    33061 gtggatccca gtttctgcta ctacgtgaaa ttctttcttt tccatattaa tcggtctcct
    33121 ttaagtgagt gttgttttta tgtgagggtt ttctttttta gtaattcaga gaatcctaac
    33181 aaatgccacc ctttcatctg taaagattaa catttttttt cgttagatac aacagttttc
    33241 attcaatttc agataaaagt attcaaatta ttccggattc tttttcatcc ttttcttcac
    33301 attttataac aaacgtgttt atttcctttt tcttgtcgct ttctcttctc ctgacgttta
    33361 tcattctttc ctttgaccct ctttgttttc atatgaaacg aattacttgc ttcccttttt
    33421 atttttagta taataagagt caaaggtcag gaatggtcaa tagagatttc accttttcta
    33481 cctcataaat ctcttaaaaa actaggggtt attcttttac ctcatgaaaa acgagatgta
    33541 aaatatggat gtacccattt ttgtgaaagg acgtgaatga ttcatgcttt gtcaaaactg
    33601 cggcaagaat gaggcaacga ttcacttgta tgccactgtc aatggtcagc ggacacaact
    33661 cgattactgt cagagctgtt atcaaaaaat caaaaatcaa caaaatggag gtctgactaa
    33721 tatggcccaa aatgatccat ttggatttgg cagtttggac gatcttttcc gttccatgtc
    33781 tcgccaaatg caacagcaag gaaattatga gcaaacacca ccaacacaat ttggcggaaa
    33841 caacaacttc aatggtggtc agccacctca aggcaataca gaaggtttat tgggagaata
    33901 cggaatcaat atcacagaac aagcacgaca aggtgatatc gatcctgtga tcggacgcga
    33961 tgacgaaatc aaacgagtca ttgaaatttt aaatcgccga accaagaaca atcctgtctt
    34021 gattggagaa ccaggtgttg gtaaaacagc agttgttgaa ggtttagcac aaaaaatcgt
    34081 agatggtgat gtaccgcaaa aattaatgga caaagaagtc attcgtttag atgtcgtatc
    34141 tttagtccaa ggtactggta tacgaggaca atttgaagaa cgtatgcaaa aattgattga
    34201 agagatccgt caagcagaaa atgtgatcct attaatagat gaagttcacg aaatcgtcgg
    34261 tgctggttct gctggtgatg gaaatatgga tgctggtaat attttaaaac cagctttagc
    34321 tcgaggagaa ttgcaaatgg ttggtgctac taccttaaat gagtaccgca tcatcgaaaa
    34381 agacgctgct ttagaacgtc gtatgcaacc tgtacgggta gatgaaccaa ctgtcgaaga
    34441 aacgatcagt attttgaaag gtttgcaaaa acgttatgaa gactatcatc atgtaaaata
    34501 tactgatgag gccatcgaag cagccgcaac tttatccaat cgttacgtcc aagatcgctt
    34561 cttgccggat aaagccatcg atttgctaga tgaaacaggt tctaagaaaa acttgacgat
    34621 ccaaatcgtt gatcctaaaa caatcgagaa aaaactgcaa gaagcagaag aacaaaaagt
    34681 tttagcttct cgagaagaag atttcgaaaa agcagcttat tatcgcgatc agatcaataa
    34741 acttcaaaaa atgaaagaac gtcagctcac tgaagaggaa acacctgtga ttaccgaaaa
    34801 agatatggaa aaaatcgttg aacaacggac aggtattcca gtgggtgaat taaaagaaaa
    34861 agaacagaca caactgaaaa acttagcaga tgacttgaaa gctcatgtca tcggacaaga
    34921 taacgctgta gatcgagtag cgaaagcgat tcgccgaaac cgtgttggat taaacaaaca
    34981 gaatcgtcca atcggctcct tcttatttgt tggaccaact ggtgtaggta aaacagagct
    35041 tgcgaaacaa cttgcctacg aactattcgg ttcacaagat tcaatgattc gtttcgatat
    35101 gtctgaatat atggaaaaac atagtgtctc taaattgatt ggttctcctc caggttatgt
    35161 cggatacgaa gaagctggtc aattaacaga aaaagtacgg agaaatcctt acagtcttgt
    35221 cttgttagat gaagtagaaa aagctcatcc agatgttttg catatgttct tgcaaatctt
    35281 agatgatggt cgattgacag atgcacaagg aagaacggtc agctttaaag atacgatcat
    35341 cattatgaca agtaatgccg gaactggtaa agtagaagca aacgttggtt ttggtgcggc
    35401 acgcgaaggt gttactcgtt ctgtattgaa ccaattaaac aactacttta caccagaatt
    35461 tctgaaccgt tttgacggga tcatcgaatt cagtgcatta tcaaaagaaa acttgatgac
    35521 aatcgtcaca ctaatgctag acgatgtcaa ccaaatgctg gcagcacagc aacttcacat
    35581 cgaagttcct acgaatgtca aagaaaaatt agttgactta ggctatgatc catctatggg
    35641 tgctcgtcct cttcgacgca cgatccaaga acaaatcgaa gatggtatcg ctgaatttta
    35701 tcttgatcac ccttctatcc atgagttgaa agcaaaactg gataaagatg gaaaaatcat
    35761 cgttacttct aaaccagaac gtttggctaa agaatcagcc gaagaaacgg ctgaataaat
    35821 ccagttttat agcgtgagac ggtatttctt tgagaaatgc cgtctcattc ttttttcaga
    35881 aaagtcaaaa tactgttcat tttataaaaa agaaattata ataagagaaa caagcaatta
    35941 aaaatacata aaagaggtga gcgccatgaa attggtaaat gtaacaaaca gccattcccg
    36001 tcttgtatta aaccagcttg aaaacactga tgcccatcta gtcaaggtct acacagccgg
    36061 aaataccact attgtctaca ctgaagcccc tgaacataat gaaattctgc tgatcaatga
    36121 caaacgtaaa atccagccga aagaaatcga agatgctaaa aattatttct tagataaaat
    36181 caaagacgcc gtttaccacg aggatgaaat caaagtaatc gaattggcag gccttgttga
    36241 aatctcgatt ccaaaacatg aattaggcgc tacattagcc gtgtaaacaa attttgaaca
    36301 taataattaa agagcgtggg acaaaagtaa agaacacttt tgtctcacgc tctaaacacg
    36361 tataaacggc gaaagcagaa gcaactcctt cggaaataag ctgaaattca cgaaaattgc
    36421 ttttcaaatt tttgtgaatt ccagcttatt tcttggagtt aaacgcttct gtctcagcct
    36481 ctttttcttt ctagcttttt gatttttctc ttttcttttg tacttttctc ttttcatttt
    36541 cagttctacg cgtgtcttta tttttaactt tttcctcttt atggatgatt gatcgtactt
    36601 tttgtgcaat ttgctcgttt ttgtcccagt cttttacatc taataatcga cataatcgta
    36661 acatctcttc ttttttctgt ttttttcttt cacgtctttg ccattctgtt tccatgtgtc
    36721 acactctcct ttctttaatc atatgtacgc aaaataattt ttatattttt ttgattagac
    36781 atttctatga ttttaatata gtaaaaagag ccgtcacgga aaatccgtca cggctctaaa
    36841 caaaatatga gaggctgttt ttgtttggct attcttatta cttgatgcag ggcagcttgt
    36901 gtcaagactt ctttacatca aactttttaa ttttacattg ggatatttat ccgcaaacca
    36961 gcgttctgca aattggttct cgaataagaa caacggttgg tcgaaacggt cacgagccaa
    37021 gatattgcga cttgaactca tcttctcatc caaatcttct ggatcgatcc agcgagcgat
    37081 tttgtgtccc attggagaca tgattacttc ggcgttatac tcatttaaca tacgatattg
    37141 gaatacttcg aattgtagct gaccaacagc tccaatgata tattcttccg ttagatatgt
    37201 tttataaagc tgaatcgctc cttcttgaac taattgatag attcctttgt ggaaggattt
    37261 ttgtttcatg acattttttg cagtcacttt cataaacagc tctggagtaa atgaagggag
    37321 ttcttcataa gcaactttta gttttccttc gaacaatgta tccccaatct gataattgcc
    37381 tgtatcatat acaccgatga tatcgcctgc tactgctttt tcgacgtttt ctctcgaatc
    37441 tgccataaat tgtgtgacat tgcttaattt cagtttttta tttgtacgtt ccaaccagac
    37501 atccattcct cgttcgaatg ttccagaaca gattcggaca aaagcgattc ggtcacgatg
    37561 ggctggattc atatttgctt ggatcttgaa tacgaaacct gaaaattctt cctcataagg
    37621 acttaccatc tgatcatctt gtgttttgtg tccataagga gctggtgcca attcaacgaa
    37681 agtctctaaa aaagtctgta caccgaagtt agtcaatgca gaaccaaaaa atactggtgt
    37741 ctgatcgcca cgagcaattt tttcttgatt aaatgcatct ccagcctctt tgattagttc
    37801 tacttcttct aagacttgtt catataagga attttcagtt agaggatgat tttcgggaag
    37861 cagtccatct tcatccaatt ctactaatcg ttcatcctga taattttccg gacgataaaa
    37921 ctctacacga ttatggtaga tatcataaag accttctagc cctttaccca taccgattgg
    37981 ccaattcatc ggataagatt cgatatctaa tagctcttct aattcttcta acaattccaa
    38041 tggttcacga ccatcacgat ctagtttgtt gataaaagta aatatcggga tgccacgttt
    38101 ttttacaact tggaataatt tctttgtctg tgcttcgatc ccttttgcac tatcgattac
    38161 catgaccgca ctatccacgg ccatcaaagt acgataagta tcttcagaaa aatcttcatg
    38221 tcctggtgta tccaagatat ttactcgttt cccttgataa tcaaactgca taacagaact
    38281 agtaacagaa atcccacgtt gtttctcgat ttccatccag tctgatttgg caaaattacc
    38341 tgtttttttg ccttttacgg tcccggcttg acggatagcc ccaccaaaca atagtaattg
    38401 ttctgtaatc gttgttttcc cagcatccgg atgggaaatg atcgcaaaag ttctgcgatt
    38461 gtccacttgt tgctttaatt ttggattatt cataacctaa ctccatttct tccattcaat
    38521 tatttatatt ttctctaggc acagattgtc cgatctctta aagaaagaca atttcatata
    38581 gggctgtgac aaaagccgtg tagcagtctc tttttccgag taaacggcgt tctagagaca
    38641 gcctatcagc aataagccca cccaagccaa aaatacgaaa agctgttttt gcttggctgc
    38701 tcttattact taatgcagga tagctttttc acaacctttg tcaactacta caactgaatc
    38761 agtatagcat ggattcagcg aatgaaaaag ccaccaaacc ataagagtca aatatttttt
    38821 tgtcagctga ctaaaagaaa agacgtgttg cttgtttatt caagcaacac gtctttcata
    38881 accaagtttc caattatctt cttggctcgt catcttcgaa ttcttttctg aagtatcttc
    38941 gttcttcttc aggttccgct tctgtttctt ccggatcatg aaaaatgaca cggattttaa
    39001 ggattcgaga accttccatt tcttcagaaa ccagcgtaat attatcgaca tcaaacgata
    39061 acttttcgcc ttcatccgga atcatgccta atgctgtaat caaataacca gccatcgtat
    39121 ctacatcact catatgcaga tcactgtcaa aagcttcatt gaactcatca atcagcatac
    39181 gtccttggat gatatattcg tgttcatcga ttttttcata aagattctca acttcatctg
    39241 attcatcatc gatttctccg acgatttctt ctaaaaggtc ttctagtgtt gctaacccaa
    39301 cgacgccgcc atattcatct aataaaatag ccatctgatt ctgcgtcttt ttcatttcat
    39361 ataacagatc atcaataaag accgtttcag gaacgaataa aggctcctgc atgattttct
    39421 tgatatctaa attatcaaag ccgaatttat gggcagcttt tagtaaattc tttgtatgaa
    39481 ggattccgac tactttatct ttgtcttcgt tataaacagg gattcttgaa tagttttcgg
    39541 ataaaacttc attcacattt tcttccacag tgtcgttgat atcaatcata aatgcatccg
    39601 ttcgtgggac catgacttct cgggcaactt tcgtatcaag agaaaaaacc ccttggagca
    39661 tttctaattc ttcattattc aatacgcctt cgttttcaag catataacgc atttcatctc
    39721 tggtcatttt tgaatcttca tcatcaaaag tcatcggcgt gatacgcgcc aataaacttg
    39781 tggaagcaga aagcagccag acgaagggct tagctactac accaatcaag cgtatcagcc
    39841 ctgaagtgaa ctttgcgact tcttctgatt tatttaaagc aatacgttta gggtacaatt
    39901 ctccaaaaac aatcgataca taggtcaaaa tagccagcac aatgatattt gcaatatttt
    39961 ttgccgctgt gccgccacct aataccggag ctaaccgttc cgataaagta ttagctagtg
    40021 aagcaccaga caaaatgttg accaaagtga ttcctacttg gattgtcgat aggaaattat
    40081 ttggattctg caatattttt aaaagctttt gagatttcac atctccttca tcagcttttt
    40141 gctcgattcg attcttattg atcgaaacaa cagcaatttc ggaagctgct aaaaaagcat
    40201 tgatcaatgt caaaacgatc aataataaaa tctgcgctaa cagcgactga ctctcagggt
    40261 cagcattcat aatcgcattc tctccttata aaattaattt ttagtttacg atagaaaaaa
    40321 acgtggcact atagccacgt taaaatggta tcacaaagca attttctttg caataaaaac
    40381 aagtgtacta aaactaccta cgaggtcgta gcaattttct tcttgttttc attttgcttg
    40441 tcttctttga cgattttgat tatataggaa atgatcgtct tgcagattgc gtaaaaagga
    40501 acacctaaga agataccaag caatccggca atatttccag ctactagaag aacgataatg
    40561 atcgttaatg gatggatttt cagtgatttc ccaattacat taggataaat gatattccca
    40621 tccaactgtt ggacgattag cacaaccaca caacaaagta atgcttttac cggatcattg
    40681 aagactgtta ctagaaatgc aggtgctagt cctagataag gtcctaaata tggaattagg
    40741 tttgtcaatc ccgcaatgac cccaaataag aaagcataat ccacaccaat taccatatat
    40801 cctaaaaatg tgaaggtacc aacgaataaa cattcgattg cttgtccgct aatgtaatta
    40861 gccaatgttt tattcagttg ccccaataac tccacaattt ggtttcttct tttttctggg
    40921 aaaaactgtt ggatgtttgg cactagtttt tctccgtctt tcaacatata gaacaagatg
    40981 aatggtgctg taatgattac tacggttgcc gaagcgatcg ttccaacgat cgaacctaaa
    41041 ctattggata ctccactaag gaattgctga atgattgtcc cgtaagaaat gtctaattgc
    41101 tcaaaatatt tattgatatc tacttccttg aacaaaggca attcggctac ctcttttaac
    41161 cagctttcta cctgtttgat gaaatcaggc atattagatg ccaatgagga aatttgctgt
    41221 actagacttg ggatgacact aagtaaaatc caaataattg ctgcaactaa aaggagcagc
    41281 acaattgcga cagcccatat tcttttgatt tttgctttca tcaacagctt gacaatagga
    41341 ttcaataaat agtaaagaaa gcctgcaatc agtacaggtg caaataacgt ggaaaaaaat
    41401 gtcccgatcg gttcgaaaat aaagtttatt tctgatgaaa tcatgatcaa tgcagctatg
    41461 atcaataatt caagcgacca aaacattagt ttagactgtc taagtttttc aaacaataga
    41521 tttcctcctt tctttcttac tagtatatat tatattcgtt aaaaattctt ttattctttt
    41581 tttatttttg aaaacttgcc atacttttta tttgttttat tttccagtat actatacgaa
    41641 aggaaggtgg ctagaccatg aaagttgtac aaacaaaaga tacaatgagc aatatttact
    41701 tagatgctgt acggatcagg catcaagttt ttgtagtcga acagggtgtg cctttgtctc
    41761 gagaaataga caaagatgaa gcccattgta tccacttcgt cctgtactca gataaaaaag
    41821 aaccgcaagg aactgtacgt cttttgcctt tagaaaacgg aaaaatgaaa ttacagcgga
    41881 tggcgattct ttctgaatac agacaccaag ggttaggaaa aatattgatt gaagaagcag
    41941 aaaactttgc taagaatcaa ggctataata cgattttatt aggggcacag tccacagctg
    42001 aaacttttta cgaaaaacta ggatatacag cttacggcga tccttttgaa gatgctggca
    42061 tgcctcatat ttatatgaaa aagactttat aaaaatttat ttcgaaaaaa gcaaaaaaca
    42121 gcaagctttt gagaaaaatc tctcactggc ttactgttct tttttgtgtt tacttacgcg
    42181 acaattgctt gtaacggtta taccaaatat caatatagcc ttccgagaac gggccatctc
    42241 cattattgat ccagtcaacc agaatcttca cattttcttt taggatgaag tcaatatcgt
    42301 tcgggtaatt catcattttg ctgtgcatct catattcatc gacatccaat agtcgtttct
    42361 cgccgtcagg aaataccttg atatccaagt catagtcgat atatttcaag gcctcatcgt
    42421 ccagcaaaaa aggtgaagct agattacaat aataggaaac ccccttttct ctgatcattg
    42481 ctattacatt gaaccagtat tttttatgaa aataaacaat cgctggttcg cgcgttaccc
    42541 atcggcgtcc atcagattca gtgactaatg tgtgatcatt cacgccgatc atagagtgtt
    42601 cgcttgtttt taataccatg gtatctcgcc acgttcgatg caatttgccg tcgtgcttgt
    42661 aactttggat cgtcacaaac tctccttctt ttggaactcc catagcaacc cttccttaag
    42721 cagcattttg tgctttgtgt ttgggtgttc attacaccga catcataatt attatatcaa
    42781 taaaaatgag ctttgcctag aaaggattcc tattgtttcg atttttctct aactgatcta
    42841 ccagtttcat ttggacctta ggaaaaacga ccgaatcaaa tgcatcaggc ttcaaccact
    42901 tcgaagtttt gttctcggta aattcttgtt ctgctccctc ggttgcccgt ccgtaaaaaa
    42961 ggagaacatg ccatttcaga tgactaaaaa tatgagtaac ttctcctaaa tgtcgtgtct
    43021 gccaaacaaa gagttcctgc ttttcaaatg ggagattttg ctcttcttct gctactaggt
    43081 catcaaacag atcgatttct ggctttgttt cccattcttt tttcaatcgc tcatactcct
    43141 cttgtgtcac ttccatcatt ggaaatgtcc acatattcgc cagcaatttt tggctatctc
    43201 tttcttcaaa ataatacgct ccagaatgat tttgaagagc tgcactgata taataaacgt
    43261 cttttggctt tgcttttttt gtttttacag gaaaactcgt ttggattcct cgtttgttag
    43321 ctaaacaaaa ggcttggatc ggacaagtct cacactttgg agaagttggt gtacagatag
    43381 ctgaacctag atccatcatt gcttggttga attcacctgg atgcttttca tcaatgattt
    43441 tccgcatcgc ttcatcaaag attttcctgc tagaagcttt tgcgatgtct gcttcaatgc
    43501 aaaacaatct gctgactact cgcatcacgt tgccgtcaac tgcaggttct ggaagtccaa
    43561 atgcgatact tgcaatcgcg cctgtcgtat atggtcctat tcccttcaat gagctaattt
    43621 cttcaggcgt ttgcggcatt tccccatcaa attctgacat gatctgttta gcagcagctt
    43681 ggatgttccg ggctcttgag taataaccaa ggccctccca tgcttttaaa agcttttctt
    43741 ctggagcatt tgctagctct tcaattgtag gaaaccattc catgaaacga taaaaataat
    43801 cgatcactgt gtctactctg gtttgctgaa gcatgatctc agagatccag atacgataag
    43861 gatcacgatt atagcgccaa ggcaggtttc ttttttcttg ttcataccat tgaatgaact
    43921 gatcttgaaa ttcttttgtt tctttatctg tccatttttc ccattcttta ttcactttcc
    43981 tcttcctttt ccgtaatgaa tcgctggatc atatccaaat caaatccttt ttgatataag
    44041 ctttgcttta cttttagatt tcttttttta ggttcaaacc ttaaatttct tcgccatagt
    44101 ttatctcctt gtttgactaa ataatcatat tctatttctt gatctgcttc ttgcggaaga
    44161 tcagctatcg cttgttggat cacttcttga gaaaagcctt tcgtcatcaa tgtttgttgg
    44221 atttttctca ataattcttt ttggcttttt ccgtgatttt ttccaaacgc tttttcggct
    44281 gtctgatgtg cattttgaac ttggtcttca aatgtatatt ggctgagcgc ttgttcaatg
    44341 atttcaggtt tcaaaccttt ttgctgcatc tgctgcgcta atttctttgg tcctttgtca
    44401 cttaagcgca tattcgtgcg cacataactt tccccataga ccaaatcatc gacaaggtcc
    44461 aattctttta agcgggctac gattttattt cgatcttctt gaaggatttc cttttctttt
    44521 aagtatgttc ggatttcttt ttccgatcgc aactgataac ttaagtaatt cattgctagg
    44581 tgaaaaccga aatcagctcc gctactcttc ttgatctctt ggatagtttc ttcgtctaat
    44641 tcccgtcctt ttaataatcg atagcgtact aatacatctt cagatacttg taaagcttct
    44701 ccttcagata aatctacgcg atagaaaggg cctttgcctt tactgattct cgtaacggtt
    44761 aacataaaca tcctcctcga acatatattc tctatcatac cacagaaaat ccccgtaatc
    44821 aggtattata tgttagaata aaccacagaa aaaagaaaaa gggagatact tatggcagaa
    44881 acaattgtca aaactggaca aacggttcct ttgaaaatca agcgtttagg cataaatggt
    44941 gaaggaatcg gttatttcaa acggttgatc atatttgttc catatgcact accaaaagaa
    45001 gaagtactag tgaaaatcac gaaagcaact cctcgctatg cagaaggaga attaataaaa
    45061 gtcaaaaaaa caagcaaaga tcgcgtagtg gcaccatgtc ctgtttacta tgaatgcggt
    45121 ggctgtcaat tacaacactt agcttatcaa gctcaattgg attttaaaaa ggatctgctt
    45181 ttgcaagcat tggaaaaatt caaaccagca ggctttcgat cttatcaact tttgccgacg
    45241 atcgggatgg atgagccttg gcattataga aacaaagcac aatttcagtt acgaaaaaat
    45301 aagcagactc aaaaaattga agctggttta tacgaagcaa actctcatca gttagtccct
    45361 ataacagact gcttggttca agaacctcga acacaaaaag taatgaatac tgttgttcaa
    45421 ctattgaata aatttgatgc acccatctat gatgaacgga caaacagtgg aatcttccgc
    45481 acaatcatgg ttagaatcgg tgttaaaact ggggagttac aagttgtttt tattactcgc
    45541 agtaaaaaat tcccgcaaaa aaacgcaatg atccgtgaga tcaatgaacg actgcccgaa
    45601 gttgtttcaa tcatgcaaaa tgtccaggca caaaaaacgt ctctcgtgat gggggatgaa
    45661 acgatccact tatggggaaa agaagccatt gaagaacaaa tcaatgaagt gactttcgat
    45721 ctttctcctc gtgccttctt tcaactcaat cctcagcaga ccgaattgct ttatggcgaa
    45781 ggaatcaaag cattagatgt ccagcctaat gaaacgatcg tggatgctta ttgcggagtt
    45841 gggacgatcg gcttaagtgt agcaaaacaa gccaaagaag tacggggaat ggataccgtt
    45901 cctcaagcaa tcgctgatgc aaaaaaaaat gcggaaagat taggatatca caacactcga
    45961 tatgaagtcg ggacagcaga gcaagttctg cctaaatggt tgaatgaagg ttttcagcct
    46021 gatggtatca tcgtagatcc accacgtacg ggtttggata acgcattgat ccaatcatta
    46081 ttgaaatacc ctccaaaaaa acttgtttat atctcctgta atgtttctac acttgccaga
    46141 gatctggtta atttaagtaa aaagttcaag attgaatatt tacagtccgt cgacatgttt
    46201 cctcagactg cacgttgtga agttgtcgtg aagatgacga gactcgctga ctaaatgaaa
    46261 gaggttgtga aaaagtctgc cctgtatcaa gtaataagaa cagccaaaca aaaatagctc
    46321 ttcatgtttt atgaatactg tacttgtgac cgaagagtta acaggaggac actatttatt
    46381 taaaaaaagg gttgtgacat agtttttgtc acagcccttt ttgattatta ttggatattc
    46441 acgtctatca cttgataaaa tgcatttgtc gtatcgctga tattccatac tgctaaaatc
    46501 acattatatc cttttcgatc ctgcggaagt gtgatcgttt ggttgactgt ttttggtgga
    46561 acagttgctt tgtcgtctat ttttgtgatc aattcaaaat cactaaattt caaaggttga
    46621 ttaggattcc aagttggttt ggtaatgtag taatcccaag tacttgtccg atgttgtgct
    46681 gttaaattcc aagtaatatt taatgttcct ggattaacca tgtttttatg ccatctgtta
    46741 gatgtctgtt catctaaagg ctcaaagccg ctgactcctg cactagcaat ttttccatca
    46801 atgaatgtat ttttggtagc ttcgatactt tgcggttccc attgtgctct tccgacattt
    46861 tgatttaagt ttcctgctgc tgatgttcct aggtatgcac ggcttcctgg agaagtaata
    46921 taaccatgcg caaaacctgg aatgctaaaa ccgaacaacc ctaaactaac taacccaata
    46981 aacaataacg tactaatctt tttcatgtag aaacctcctt catttgataa ccacattgta
    47041 aacgctttat tgtattaaca caaacattat gcttttataa ttttatgttg aagtaaaaaa
    47101 ggtgaaaaaa gtaagatgca gattataaca gaagtagacg agaaaagtac aaatagaaaa
    47161 catgagaatc aaatcatatg atctttttca aaaacatcat tcatataaac aaatgttcaa
    47221 ctttttaata acaacaatta tcaatttttt tcttacttca caaactaaat acaggtcttg
    47281 ctgtgagcct tcatggtaaa ctaatattat agaaaggagt tagtaaaatg aagatgataa
    47341 aagatattcg tttttgggtt tgtgttatag gaattgtcat attaggcttt ttatcagggt
    47401 tgcttagcgg aaatcccgga aaatattact attctttgca acttccacca tttgcaccac
    47461 ctagctggat atttgggccg atgtggacct tactgtatat attgatgggt atttctcttt
    47521 atttgttact taatcacaac aacaaaaaac agcgaaacaa tcttgtcggt ctttttgtga
    47581 ttcagttcat ttttaatttt atatggtctg ctctattttt taatttaaga aatattttca
    47641 ttgcagcaat cgatattaca cttttagtta ttttcttgtc agtgcttatg tatcagttgt
    47701 ggctgcatca tcgcctggca atgtggctca tgattcctta ttatttatgg gtactattcg
    47761 caactctatt gaattattca atttattttt taaactaagc gctaaaaaga gacgtcctgt
    47821 aatttaacac atagaaaaag tgccacctaa gttagatttt ttgtctaatt taggtggcac
    47881 tctttattaa ccaaactatt tttttctagt acccacttgt tgttccatac tcattattct
    47941 ggtcataacc ataaccattt tgttcctgtc cagcgtaagg atcataactt tgagtatctt
    48001 gacttggtgt atagtactga cttgtatctt ctgtttgctg ataataggta ttcggatctt
    48061 ggtactgatc atatgtgttt tctgaatagg aagaataatc ggtgtaccct tcactattcg
    48121 atccatcacc gtttgtcgaa tcgccatctt ccgaatcatc aaagaacatc attgaagcat
    48181 tctcattttt caaattaggt aatgtatcgc ttgtttttat atttaattgt ttcttcagtt
    48241 cattttggat cgaaagaaga tcattttttc ctaaaatttg atagtagata tcattgatca
    48301 tttgtccttc gccttgcaac tggtcttgtt tgattgtttc aaacgccggg gtgtagttcg
    48361 tcgctacatc aagcatgtca tcccaatcta agtccgtcgt cacattgttc tcaactgctt
    48421 ttaaaatttt tctataattg cttacgccat ctaaacttaa aactttattg acgattttcg
    48481 tcactacttc ccgctgacga cgttgtcgac cgatatcgcc ttctggatct tcgtgtcgca
    48541 ttcgagaata ggctaaacct ttttctccat tcaatgtttg ttcacctact ggtacatgga
    48601 caccatccaa agtaaagtca attttattat tcactttgat gccaccgacc gcattgatca
    48661 aatcttccat gccatccaaa ttgatcgtta cataatgatc aataggaata tcgagcagtt
    48721 gctcaattga atccatggcc atttcgacac caccaaatgc gtaggcatga tttaatttat
    48781 ctaccgttcc ataacctacg atattcgtat aaatatctcg gtccaaactg atgatcgttg
    48841 attttttttg tttcggatta actgttacta ccatcatcgt atcagaacgt ccttgttccg
    48901 ttcttcctaa tccaccggta tctaaaccta atagcaaaac cgaaaaaggt tctttgtcat
    48961 caatgcttac tctctcagaa cgtttggagg atattcgatt agagttttta gaaattttgt
    49021 ttactgtttg gctcgcttct cccataaatc tgattccgta tgctgataat ccggcaatca
    49081 gcaaaacgaa tacccctaac aaggttaata gaactttttg ccatcgcttc ataatacacc
    49141 tctgtttcac attttctaaa atattgtctc atataactgt tcaatcagca aattcacttt
    49201 ttaatcataa gaaaacttta aaaaacattt ttgtgtaacg attattattt tttaaaattt
    49261 ctcaaaattc ttaactatca taccataccg tgaaaaagat cgaaagaccg aatacacgca
    49321 gttcgcaatc gttttatctt tttttatgta ttttttccag aaaaagcgaa caacaaggta
    49381 ttttccaaat aatcgtgcag taaaatgatc gcacatacct ttcccatctt tttaacagtc
    49441 tttgcctacc gttcagatta tcattcgatt tcacgacaat ttcttcctat gactggtcct
    49501 tttgttaaac ccatcttcta ttcgttttat ttccagctca ctgcatggct cttaaaatga
    49561 ctcgaactag tgattgcatt accatcatct tttaatggat agatatgctc ctcttcaaag
    49621 taaaacgatt ttcttttaaa gtaatagaat tgacatggta atgagtatgt atactagtgg
    49681 tttcacaaat ggtcttttat tcaacatcca aaaactgaaa tttctttaaa atccattact
    49741 aacgaagaaa atgttccttg cttgataatt agttaggaca tgtcaagtga acaaatgcat
    49801 ttacttagcc aaaaaatcta aaaacttcat aaatagacaa aaagacacga ctctctaaga
    49861 agtcgtgtct ttattcaaca aattattata atttagtcac ttcagcagct tgaggtccgc
    49921 gtgcaccttc aacaatcgtg aattctactt cttgaccttc ttctaggctc ttgaagccgt
    49981 ctccttgaat tgctgagaaa tgaacaaata cgtcatctcc gccgtctact gtaataaacc
    50041 caaatccttt ttcattgttg aaccatttaa ccgttccgtg ttccataaat gtatatcctc
    50101 caaaaaagtt cttgcaagta accttgcaag aacattatac ccaatttaga aaacgctagc
    50161 aagctttcgc tcttttattt tccaaattat ttttaagact gatatgacgg aggaaatggt
    50221 tattttgctg cttcgaaacg tttgtttact tcatcccaat taataacatt ccagaatgct
    50281 gcaatataat ctggtcggac atttttatat ttcaaataat aagcatgttc ccaaacgtcc
    50341 aaacctagaa ttggtgtctt tccttccatc aatggagaat cttgatttgc agtagaggta
    50401 atagctaatt ttccattttc cattacaagc caagcccatc cagaaccaaa tcgtccagcg
    50461 gctgcttttt tgaattcttc tttaaaagaa gaaaaatcac caaaagcttc attaatcgct
    50521 tcttttattt ctcctgtagg ttcgccacca gcatttggtg ccatgatttc ccagaaaaat
    50581 gaatggttag catgtccgcc accattgtta cgtacagctg tcttgatatc tgttggaata
    50641 gcgtccatat cagataataa ttcttctatt gttttttcgc ctaattctgg gtatttctca
    50701 attgctgaat ttaaattcgt cacataagta ttgtgatgct tatcatgatg cagatgcatc
    50761 gtttcttcgt caatataagg ttccaatgcg tcatatgcat aaggtagatc tggtaatgtg
    50821 taagtcataa aaaaattcct cctcaatgtt ttcttaataa tgtctacatt acaaagagta
    50881 acaaagagaa ggaaattctt caattgttat gcctagtcgt ctttttcact ttgacctact
    50941 tcttcttcaa aaacctcagt ttctttaaaa ataaacaact tgctgaaaat atagttcgca
    51001 aggataacaa taatttgagt gatgattttc gccacatact cattgctgtt cataacattg
    51061 atcaacaata ccattgcccc catgtccaat ccgtaagaaa ggatacggta gaagaagaac
    51121 ttaccgcatt caataagtgc atgtgtaaaa ttcggtgatt ttgaatggaa tacccaaagt
    51181 ttgttcgtta caaaagcaaa caatacagaa caaaaccacg aaatagaatt ggataaggcc
    51241 atacttaaat caaaatattg gcgtgcgaga gcaaaactaa caaaatttac aatcgtagcc
    51301 aaaccaccaa aaaagagata gactagtatc tcccaatatc cttttgcttc taaatatcct
    51361 tttaactgtc gatactgctt catgagccaa cctaccttat taaaaattct tatttatcat
    51421 actctatatt tcaataactt tcatctttat ttaaaaaaat taattttttt tgatcctttg
    51481 cctttgtctc tgcttggatc gtcacatgtg taataccata ttttaatttt aataaagaaa
    51541 ttatacgagg atatatcttt tcaatctcgc ttagtagctg atcttcaaaa tcaatatgtc
    51601 cgtcgaaaat aattatcttt tcgctatact gccaaatatg gacatgatga acatccttta
    51661 ccccatcgat tgcttcaatt tcttgttcca ttttttcata gtcgatagca ggtgcacttt
    51721 gtatcaaaat agcggcagct tttttgatca ccattatcgc ttctatcaat atatatatcg
    51781 aaatgatcag tgtaataact ggatcgatcc agtagatatc gaaaaaacgg atcaaaattg
    51841 ctccgataat cacacttacc gaagacagtg tatcacttaa caaatgcaaa taactagatt
    51901 ttatattcaa actttcatct gcttcttgtc gtaataataa tactgagaac aaattcgcga
    51961 gcaatccaat aactgctact gttagcatca aatgactatt tatcttttct ggtgaagtga
    52021 accgcttgaa tgcttcaacg gttaaaaaca aggataatat gatcaatatg aatgagttga
    52081 tgaaagcact caatatttct aaacgctggt agccatacgt acgtttttta tttgcttctt
    52141 ttcgggccat tttttgtgcc ccgtaagaaa aaataattgc caatgtatca ctaaggttat
    52201 ggaaagcatc tgaaacaaga gacaaactcc ctgacataat ccctccaata aattctgata
    52261 aagtgatcac cgcattcaaa accactactc caaatagttt ttttgatgat ctctgtggct
    52321 gtgtaggcac tattccttcc tccattttat ttatattgga tagtctttag acaagaataa
    52381 catttttttg atatttcacc aatcattcag ctgtttcctt aaagcacttg tatttcactt
    52441 gatacttcgc tagaattgca agtgatgaca ctactagatg aggagtactt atgacaacaa
    52501 aacaattaat tatcagttcc tttatacgat tcaaagacct aaaggaggcg agaaatgtcc
    52561 cattttggaa agccattgtc tatcttttag ttttgagtat aattatggct ttgccaatct
    52621 cttttcaagt ttttcaagtc ttaaacaaca ttcaattgga tgggcaaaag attgctactc
    52681 gcattcctga ttttacaatc caaaacgggc agcttcaaac cgaagaaaaa gaaggattca
    52741 tttaccaaac aaactccatt atcttcacat ttgatccaga gggaaaacga acagaacagg
    52801 acatctctac tgatttgatg gggaattttg ttagtgtcgg gatgttaaaa aacaaactta
    52861 tcatagctct tcctaataca ggcacgactt ctgctttgtt gaacaataac caattagaac
    52921 ttccctacac caatgaatct ttaaaaaact taacaggtaa gcagctccgt tcttttttaa
    52981 gtgaagcatc tataccactt tggataaaag tcctgacatt tatattttct atttatccta
    53041 gttttctgaa tctgctgatc actttgctat ttaccaacat tgctgctttt ctctatgcac
    53101 gctttcgact aacaaaagct acttttcttg attgtttaaa aacattgatc tattcaattt
    53161 cattgcctac tataattgca acaatcttga tggtctttct tccttctttt gacactagcg
    53221 ccttcattgc ttttgcagga atctttattt ttgctcaagc tgtcaaagga tgggcaaaaa
    53281 tatcgatcaa ttaagaaata aagacaactc gttatttcta cttcaataga cccttttaga
    53341 ggttgtgaca tttttttgtc acagcccctt ttttatttga aaaatatttc tttctcaaaa
    53401 aacaagcaag gcgcttcaaa gttcttcttg tatgcgctac acttagagta aagaaaggcg
    53461 ggaaattaac tatgtcagaa agaatcattt atgcagatcg tccatttcgt gatgaattta
    53521 tcgaagaaat ccatactata gcgcctggtt atatctttaa aacagaatta caaccagagg
    53581 atctacaaaa tgtagagatc agtttgggct ggaactcaga ctaccaagaa aaactattag
    53641 cctcttctac cttgaaatgg gtccaatcta tctcagctgg tgttgatcag ctaccccttg
    53701 agactttttc aaagaaacat attttacttt caaatggtag tggcatccac agtgaatcga
    53761 ttacggagca tgtcttagga atcatccttg ggtattctcg tggtcttttt caagcacaaa
    53821 aggcacagag tgacatgaaa tggttaggtt catcggtcca ttaccaatct atccaaggga
    53881 aaaaaatact aatcattgga actggccata ttggaaaaat gattgcaaaa aaatgcaaag
    53941 cattagacat gaactgctat ggaatcaata catccggtca tccagcagaa ggaatggaaa
    54001 agactttttc tttaaatcaa ctaaaggaag ttcttcctga agtagatttc gtagtcaata
    54061 tcttacctct aacggaggaa acaactgggc tctttgatca gcatatgttt gaacactttg
    54121 atccaaaatc tgtattcatc aatgttggcc gtggtgcttc tgttaagaca caagatctgg
    54181 tgcaggcttt aaataaccag caactttcct ttgcagcatt agacgttttt gaggaagagc
    54241 ctcttccaca agatcatcct ctttggaaaa tggacaatgt actgattact tcccacattg
    54301 caggtttgac acctgatttt caaaagaaat taatggctat ttttttaacc aatctgaaaa
    54361 gctactttgc cacccatgag cttcaaacca atcaagtaaa attgtctgca ggatattaat
    54421 agctgaaaac aatattttca aaagaaaaaa gagaaggtga caaaaattgt gtcaccctct
    54481 ctttttttat tgttttttaa agtgataggt tggctcctcc aggttgggat cataatcaac
    54541 aagtaaatca tatcctttaa agaaccattc atctgcttcc tcgataaaaa aaagtgtccc
    54601 atcaatttcc actttcttta caggatgttc tggctgttca actgacattc caatcgaaaa
    54661 accatcatga acctctgttt tgccgtagac ttttccaaaa aaacgtattc cgtaagtttc
    54721 tggcagatca atttctgagt caaaccactt ttgtgctttt ggcgttaccg ttaatttcat
    54781 cccaacaacc tactttctct tttctttcta ttgattcatc ttatcgtcta gaatatccac
    54841 atcgcctgtc tctccaataa ccagtagatt atcattttca cgaacatatt catctgctgc
    54901 aggagaagcg ataaccgttt gatctactct tcgtatggcg actactgtta agtcaaaacg
    54961 ttgcctgaaa tttaattcag ctaatgtttt gttgaaaaat ttaggattgg agactcggat
    55021 ttctgctaaa gaatatttat ctgacaactc taggtaatct aaaatattct ttgacactaa
    55081 attatgcgca atccttattc ccatgtctcg ctcgggatgg acgacgcgat cagctccgat
    55141 cttttcaagt actctggcat gatactcatt ttgggctttt gctaaaatat ttggtacgcc
    55201 catttccttt accatcagag taactaagat actggcttga atatcttctc caatagcgac
    55261 aattacatga tcgaaatttc ttatgcctaa tgatcgaagt gtcatttcat cctgtgcatt
    55321 tgccacaaca gcatgagtgg ctatattcat atattcattg acccgatctt cattactatc
    55381 aatagccagt acttcttgac cagcttcgat cagtgttcgg cagatacttc cgccaaatcg
    55441 tccaagacct acaattgcaa aattttgttt caccgttttc ctcctttagt atcttctttt
    55501 ctcagtataa caaagccttt acaaaaacaa aagcaagcat cattattgta aaaaagccaa
    55561 gaaaaataat agttattttc tcagcttttg attatcctct ttatcatcgt ttttatttca
    55621 ccaaaccatg tttgaatgca tagatagcgg cttgtgtacg gtcttccact tctagcttag
    55681 ccaatatatt ggaaacatgt gtttttactg ttttcagtgt aataaacaat tcgtccgcta
    55741 tttcctgatt actttttcct tcagaaatca gcattaaaat ttcattttcc cgattcgtta
    55801 gttcttcatg taatacaggc tcatttcgcc gactcatttt ttccatcatt tttgttgtca
    55861 cttctggttc taatactcgc tcgccacgtt gcgttgccct tatagcatca gcaatttcat
    55921 gtgcggtaga ggtcttcaac aaataccctg ctgcacctgc ttcaatggca ggataaactt
    55981 tttcgtcatc aataaaactg gttacgataa tgattttagc ttctggccaa tcttttaaga
    56041 ttgcttttgt tgattcgata ccatccattt cttccatgac taagtccatt aaaatgacgt
    56101 ccggtcgaag tgtcatcgcc ttctcatagc cttgtcgtcc attttcagct tctccaatta
    56161 cttcaatgtc ttcttgaata gataaataaa aagagacgcc taagcgcacc atttcatggt
    56221 catctactaa taaaactttt atcatcctta tctatgcctc cttcatcaaa gggaccttga
    56281 tttctacact tgtaccttga cctttaaaac taatgatttt tactgttcca ccaataccag
    56341 ctactcgttc tttgatattg ttcaatccat aacttcccgt tttcgtttca ttcatattaa
    56401 accctgttcc gtcgtcaata atacgtaaca aaagattatt gtctattttg tgcaaatata
    56461 cctctaattc attggcttta gcatgtctta atgtatttga taacaattct tgaacgattc
    56521 ggaacaagtg atcctcaatg gaactagata gttttacatc ttctacatcc catttcagcg
    56581 aaatctggat tttattttgc aattccttca ataactgctc gataccttgc tttaaacttt
    56641 tctcttctaa attgactgga cgtagatgaa gaagcagcgc acgcatctca gactgggaag
    56701 cgttgatgat ctctgctacc attttcaact gcttgcgaaa catttctggt gtctcgcttt
    56761 tttctgcttg ctccgtcaat gccgacatca tcatcattgc tgcaaacaat tgttgcgaaa
    56821 ctgaatcatg cagctcacgg gctaatcgat gtctttctaa ttctaaaatt tcttctttgg
    56881 tttgtccatc tacatattgg ggacggctcg ttacaatttg taattcacta gatacttcaa
    56941 tcattttttc ttttatctta gtgatttcct tatcaatatc tttgatgtat aaatcgtccg
    57001 atgcacttgg gatcggaaga agcaacaatt tggattcata attgccagaa gaaagtgcac
    57061 gcagcttttc ttcgattttc ccgtattttg tcttttgaat aagtgataat aatagaaaga
    57121 caattaatcc tacacctaag gaaatggcta acaaatggaa gataagcgga acatataata
    57181 aacgtgcacg cagtaattct ccccaccaat gactttgatt gctggcataa aaataagtga
    57241 aaagtgaaaa tagaataata aggaaagccg caatccccga ataaacagct agcatcgctc
    57301 tggatatttt tcccatcata ttcgtatcac ctcgacatct ccaatcaagg tattagtaat
    57361 aatcttcaat ctacgagggt tttcatcata atcactgctg tagattttga tttgttcatt
    57421 tttcaaagaa aattgctctt cttcaaacaa gacatttcct actaatgtcg catgctctaa
    57481 tcggatggct acgcccaaag gtactaagat ccgtgttctg cctatccctt ttcttacaat
    57541 cacaatatta tcatcttttg gcaaaagcgt attgcccaaa tctatgatag tatcaccaga
    57601 aatgacggcg atgttgatat cgtcccattc atagacgtcg tttccaatac gttggttacc
    57661 gaataattgc tgtcttttcc gctcattatt atgtgttttt aattgctctg tttggatcat
    57721 catgatctgt ttctttcgcc aaaaagcatt tttggttaaa tctatccctg aaatctctac
    57781 acctttcaga ccaataaata aaacggcaaa tacagccatc atccataaag caggactgtt
    57841 gactaagcta aaaaaaatga ccaaacttcc taatatcaat tgaaaatttt gaaatttagt
    57901 acgaggatgt ttgcgcatag ctagatatat attgaaaata ccgaatatca ctaaaagcaa
    57961 aagtccagta ttgtttacga tttgccaaac agcaaataac agcagtagtg cttcaactac
    58021 cacaaaaaaa cgccaagaac tattcatcgc tctttctccc tcctgacaca ttctcatttc
    58081 atcataccta tttttttaac tgttggctat aggactttag atgtaagatc gtttgttgaa
    58141 atctaaaata cacaaagaga aaaagatcta gagtgtatca tcagtaagat gaactctcta
    58201 gatctttcag tcagactacg cttgttctac tttgacgatt ttaactaaca tatcgccacc
    58261 tggagtagca atagttactt catcattttt acgtttgcca atcaatgctt gcgcaatagg
    58321 agaatcattg gaaattttgc cagaaaacgg atctgcttca gcgcttccga caatcgtgta
    58381 ctcttcttct tctccatctg gtagttcgat gaatgtaact gttttaccaa ttgatacctc
    58441 atctgcatct acaccgtcgt tatcgatgat ttgagcaaaa cgaatcatat tttcaattgt
    58501 tgtgattctt ccttcaacaa atgcttgttc atctttcgct gattcatatt cagagttttc
    58561 ggaaagatct ccgaaaccgc gggcaatttt gattcgttca atgatttctc cgcgtttgac
    58621 tgtttttagt tcttctaatt ctttttctaa tttttcttta ccttctagag tcattggata
    58681 aactttctct accatgtgta acgtctcctt ttttcgataa aataccgcaa aaggtaatct
    58741 tttgaggaat atagtccaaa aaagattacc acgcttttct tcaaatgtaa atgtttttct
    58801 aaaaatgatc aatgtctaga gcctgttttt ctaagaatta tttacatatt tttccactaa
    58861 ttccatatgt tcttcataag ttttagcgaa ataaacattt ccagtgctcg tatctgctac
    58921 gaaataataa tagtcatttt ctgctggttc taatactgcc ttgattgcct cttcgcttgg
    58981 attgtcaaaa ggtccaggtc catagccggt attggtatac aaattatatg gtgaatctac
    59041 agctgtatct tcatacgtca ctaattcttt gtgttcacct aatgcgtata aaacagagat
    59101 atctgactga agtggcatat ttgctttgat tcggttaaag aagacttgtg caatgttttt
    59161 acgatcattt tcttttacgc cttctttttc aactagagaa gctagagtta aaacttcttg
    59221 tacagtcaaa tttttctgct tgatagctga ataatagttt tgcatgaccg tattcgtctt
    59281 gttcaccatt tcaatcacta gatccttaag cgaagtactc gtgtaataat catatgtggc
    59341 tgggaataag taaccttcca aacggtattt tgtgttctca gctttagatg cactttccaa
    59401 cagttctggg aatttttggt gcaactcgtt aaagaaagtc tcatcattca ctaaatctaa
    59461 aaattctttc ttgtctttac cagttacctt cgctacccgt tcagcaatct gatcgatatc
    59521 gtacccttct ggaatggcaa ttttcccatc tgcaactttt gttggctcag aagtaccgcc
    59581 ttcttgcaac tgtttgccaa tctcgtcaag agtcatatta ggcgctaact gataatagcc
    59641 agcttgaaag ccagttaaat ttttaaattt tgtataataa ttgaaaacaa tcccgctttt
    59701 aataatattg tccttctcca aaatctcacc aatctgcttg ttagaagagc cactcgggat
    59761 ctcgacttgg actaattggt catctgattt atctaaaggc ttcaacccgc tatctacata
    59821 acgatacacg gtaaatccaa gaaatccgcc aataatcaat aatgtaagag caatcactaa
    59881 aatgatcttc ctcacaatct tatcttcttt tttacgcaga tttctccgct tgtcgattat
    59941 atctgctgta gctgccttac tggcttcttt tttatcttta cttgggtgtt gtttgtttcc
    60001 tgacaaaaca actcctcctt actatcaagt tcgtaacttt attcattata catgatattt
    60061 gaattggcgt gaatgatttt atttaaatat tctatcaaaa atgtaagtag taaa
//
LOCUS       DAIGWC010000006        59637 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.006, whole genome shotgun sequence.
ACCESSION   DAIGWC010000006 DAIGWC010000000
VERSION     DAIGWC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.006"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(451..1761)
                     /locus_tag="NOB74_000405"
     CDS             complement(451..1761)
                     /locus_tag="NOB74_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HCI1219617.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="NOB74_000406"
     CDS             complement(1773..3191)
                     /locus_tag="NOB74_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1219618.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="NOB74_000407"
     CDS             complement(3431..4999)
                     /locus_tag="NOB74_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCI1219619.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="NOB74_000408"
     CDS             complement(5003..5413)
                     /locus_tag="NOB74_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HCI1219620.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="NOB74_000409"
     CDS             complement(5410..6333)
                     /locus_tag="NOB74_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HCI1219621.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="NOB74_000410"
     CDS             complement(6330..7208)
                     /locus_tag="NOB74_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HCI1219622.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="NOB74_000411"
     CDS             complement(7195..8532)
                     /locus_tag="NOB74_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HCI1219623.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="NOB74_000412"
     CDS             complement(8535..9638)
                     /locus_tag="NOB74_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI1219624.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="NOB74_000413"
     CDS             complement(9712..11220)
                     /locus_tag="NOB74_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI1219625.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="NOB74_000414"
     CDS             complement(11186..11878)
                     /locus_tag="NOB74_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI1219626.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="NOB74_000415"
     CDS             complement(11900..12874)
                     /locus_tag="NOB74_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1219627.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="NOB74_000416"
     CDS             13174..14046
                     /locus_tag="NOB74_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1219628.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="NOB74_000417"
     CDS             complement(14504..16702)
                     /locus_tag="NOB74_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1219629.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="NOB74_000418"
     CDS             16934..17926
                     /locus_tag="NOB74_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1219630.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="NOB74_000419"
     CDS             17986..19407
                     /locus_tag="NOB74_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HCI1219631.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="NOB74_000420"
     CDS             19400..20899
                     /locus_tag="NOB74_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HCI1219632.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="NOB74_000421"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="NOB74_000421"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HCI1219633.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="NOB74_000422"
     CDS             22491..23174
                     /locus_tag="NOB74_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HCI1219634.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="NOB74_000423"
     CDS             23176..24012
                     /locus_tag="NOB74_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI1219635.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="NOB74_000424"
     CDS             24023..25777
                     /locus_tag="NOB74_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1219636.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="NOB74_000425"
     CDS             complement(26053..26394)
                     /locus_tag="NOB74_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI1219637.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="NOB74_000426"
     CDS             complement(26462..28633)
                     /locus_tag="NOB74_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCI1219638.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28802..29701
                     /locus_tag="NOB74_000427"
     CDS             28802..29701
                     /locus_tag="NOB74_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI1219639.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="NOB74_000428"
     CDS             complement(29772..30629)
                     /locus_tag="NOB74_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI1219640.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="NOB74_000429"
     CDS             complement(30614..33316)
                     /locus_tag="NOB74_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HCI1219641.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="NOB74_000430"
     CDS             complement(33329..34618)
                     /locus_tag="NOB74_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HCI1219642.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34768..35814
                     /locus_tag="NOB74_000431"
     CDS             34768..35814
                     /locus_tag="NOB74_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1219643.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35816..37969
                     /locus_tag="NOB74_000432"
     CDS             35816..37969
                     /locus_tag="NOB74_000432"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HCI1219644.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38442..39893)
                     /locus_tag="NOB74_000433"
     CDS             complement(38442..39893)
                     /locus_tag="NOB74_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1219645.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39890..41614)
                     /locus_tag="NOB74_000434"
     CDS             complement(39890..41614)
                     /locus_tag="NOB74_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI1219646.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41607..42221)
                     /locus_tag="NOB74_000435"
     CDS             complement(41607..42221)
                     /locus_tag="NOB74_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI1219647.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42566..44023)
                     /locus_tag="NOB74_000436"
     CDS             complement(42566..44023)
                     /locus_tag="NOB74_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1219648.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44064..44984)
                     /locus_tag="NOB74_000437"
     CDS             complement(44064..44984)
                     /locus_tag="NOB74_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1219649.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44996..45943)
                     /locus_tag="NOB74_000438"
     CDS             complement(44996..45943)
                     /locus_tag="NOB74_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1219650.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46422..47141)
                     /locus_tag="NOB74_000439"
     CDS             complement(46422..47141)
                     /locus_tag="NOB74_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCI1219651.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47190..48836)
                     /locus_tag="NOB74_000440"
     CDS             complement(47190..48836)
                     /locus_tag="NOB74_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI1219652.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49015..49605
                     /locus_tag="NOB74_000441"
     CDS             49015..49605
                     /locus_tag="NOB74_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1219653.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49697..51202
                     /locus_tag="NOB74_000442"
     CDS             49697..51202
                     /locus_tag="NOB74_000442"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HCI1219654.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51286..52638)
                     /gene="celB"
                     /locus_tag="NOB74_000443"
     CDS             complement(51286..52638)
                     /gene="celB"
                     /locus_tag="NOB74_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCI1219655.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52638..53156)
                     /locus_tag="NOB74_000444"
     CDS             complement(52638..53156)
                     /locus_tag="NOB74_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219656.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53172..53498)
                     /locus_tag="NOB74_000445"
     CDS             complement(53172..53498)
                     /locus_tag="NOB74_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HCI1219657.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53511..55490)
                     /locus_tag="NOB74_000446"
     CDS             complement(53511..55490)
                     /locus_tag="NOB74_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI1219658.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55511..55825)
                     /locus_tag="NOB74_000447"
     CDS             complement(55511..55825)
                     /locus_tag="NOB74_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HCI1219659.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55993..56286
                     /locus_tag="NOB74_000448"
     CDS             55993..56286
                     /locus_tag="NOB74_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HCI1219660.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56364..57476)
                     /locus_tag="NOB74_000449"
     CDS             complement(56364..57476)
                     /locus_tag="NOB74_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI1219661.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57863..58042
                     /locus_tag="NOB74_000450"
     CDS             57863..58042
                     /locus_tag="NOB74_000450"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219662.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58236..58406
                     /locus_tag="NOB74_000451"
     CDS             58236..58406
                     /locus_tag="NOB74_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1219663.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58830..59570)
                     /locus_tag="NOB74_000452"
     CDS             complement(58830..59570)
                     /locus_tag="NOB74_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI1219664.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17827 a        12189 c        10424 g        19197 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaacttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tatcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcttccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggt tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taagccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat acttcataca gccaattatg
    34681 tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt attatttgaa
    34741 tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac aatatttaat
    34801 gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact accaactgaa
    34861 aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc attgactgaa
    34921 ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt taaatccgct
    34981 tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt tcttcttcca
    35041 tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt gatgcaagat
    35101 aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac agcaaaagag
    35161 ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca acatcttgac
    35221 ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa aaaaatctat
    35281 gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct tgctgcctct
    35341 tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca gactcatcca
    35401 caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc tggtttgact
    35461 ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc ttatatcact
    35521 aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca gaccatgaat
    35581 ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg atttgatgat
    35641 atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga ttttgaacag
    35701 ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga tcgaccatcc
    35761 gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa ataaaatgaa
    35821 tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct ctaatgggaa
    35881 ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc aaactacgga
    35941 tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct accgtcttac
    36001 ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc cgatcaatgg
    36061 aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag aagaaagtat
    36121 attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt ctacattgat
    36181 acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca gcggtttact
    36241 tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag tggaaggaaa
    36301 aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta tattgagatt
    36361 tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg actcgatccc
    36421 gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt ttatcagctc
    36481 ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga cttaccttgc
    36541 tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac accatgatca
    36601 acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc cacaaacatt
    36661 ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc gatctataaa
    36721 acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg tttatcctct
    36781 ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt tgaacagcta
    36841 tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac ttatgcctgg
    36901 gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac gagacttgat
    36961 gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac atccaaatta
    37021 tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc actaccacga
    37081 atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc aagttgccaa
    37141 ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga actatcaaaa
    37201 tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca agttcagaga
    37261 accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt ggcaaagcag
    37321 ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca gtgagagata
    37381 taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag gaggatatgg
    37441 ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat tagctatttc
    37501 aaaccagcca agttttcact atccttactt gttcagttat ataggacaac ctgaaatggc
    37561 acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa tgggttaccc
    37621 tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc tgggatttta
    37681 tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg acaaggctgt
    37741 tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc ggccgcagca
    37801 acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat attttaccca
    37861 tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc ctcaccctaa
    37921 gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac aagaggttgt
    37981 gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat cctcatattt
    38041 ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt attgagaggt
    38101 tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata gttcctcata
    38161 ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag
    38221 gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca
    38281 catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc gtttatcgag
    38341 aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt agatttctag
    38401 acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc tccactgttt
    38461 tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga gaaatacgtg
    38521 gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact gtgcaaaagc
    38581 agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact ttttttcgtt
    38641 tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc tgacacttct
    38701 ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt ttccacattg
    38761 tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag ctgctgaagt
    38821 tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc ctcatcttcc
    38881 agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata tcgtatatct
    38941 tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat tttttgagcg
    39001 acttccaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat ggtttgatct
    39061 tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata aaattgatgc
    39121 aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa agaatctgtc
    39181 tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac aaaacaacag
    39241 aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc tccgtaattt
    39301 cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag agtatcatga
    39361 gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg tcctattatt
    39421 tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa cagttcttga
    39481 tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt gattttcttg
    39541 aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac ggcgcctaat
    39601 tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat aaattcaaaa
    39661 ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc tggcattgtc
    39721 acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc ttctttggca
    39781 ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat cttttttaac
    39841 ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct catccctcct
    39901 tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac atataataac
    39961 tactgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata gaaccgtgaa
    40021 gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt tcagtcatcc
    40081 cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag actttgacac
    40141 ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt tcaactaatg
    40201 gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc ataaaatgat
    40261 aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg caaaagtcca
    40321 gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc aaagcggaaa
    40381 acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac attcggatat
    40441 attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc cgcatatgtg
    40501 cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg atgctatcca
    40561 acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt gttatgtcga
    40621 tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg atagatactt
    40681 gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg tctaaaataa
    40741 tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca ctttttttat
    40801 ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca aaattgtttt
    40861 tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg atgatcattt
    40921 cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat agtcgatttg
    40981 tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt tctaaaatca
    41041 tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct cctccttgtg
    41101 tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt tttatttccc
    41161 cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac acgatatata
    41221 tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg aaagaaacta
    41281 attcatcggt actgttttgc tgttcgtata catacatcag atactgatct atgggttttg
    41341 ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg tttttgatga
    41401 tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg gcatcacttg
    41461 tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa ataacggtag
    41521 cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga tttagtaagg
    41581 ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt atctaattct
    41641 tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat gacaccaaac
    41701 aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc aataattatt
    41761 tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag cagattagga
    41821 acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc aaataggcag
    41881 agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt gatttgaaca
    41941 gataaatata aattgtaact caataaagca gtaccagata aaaataaact aaatagcaga
    42001 ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt gatttcttta
    42061 tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc acctaatcca
    42121 aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt tataatgacc
    42181 cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc tccaaacatt
    42241 aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt gacctgatta
    42301 ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag cgaataccga
    42361 gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt agtttcgagt
    42421 agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta gcttaatacc
    42481 gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac gtcttttgtc
    42541 acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat tgtttttgca
    42601 tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat ttcggtaatg
    42661 tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc atgacattag
    42721 aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct aaaatcggtg
    42781 aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc gtaatagact
    42841 cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt gtatttggct
    42901 gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc catgcttctc
    42961 cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc agccctagaa
    43021 gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt gccatttgtg
    43081 cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct tgttttgctg
    43141 catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca cgcattagcc
    43201 aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt ggaatgagtc
    43261 cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca ttatcgtatt
    43321 ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac gtattcccta
    43381 aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa gctgccgtgt
    43441 ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa gattggattc
    43501 catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt acttgttgag
    43561 caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga tttcctttaa
    43621 tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct aattcagtca
    43681 aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag gcgatatcat
    43741 aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc cagccaatgt
    43801 aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct acttccatca
    43861 attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg tccgaattgc
    43921 tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt cccaacaaca
    43981 acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt cctcctaatt
    44041 ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag acctttgaca
    44101 aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat gactacgatc
    44161 gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg gcttcctgct
    44221 cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag atactgtagt
    44281 ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt ccagtaaccc
    44341 aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa aacgatctga
    44401 acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat cgaatcagag
    44461 accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac agccattggc
    44521 aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac aagataattg
    44581 gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa aaaacgacgg
    44641 aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt gctattgatc
    44701 agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat tttatcctgc
    44761 atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca aaaactgtac
    44821 ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa tataaatggc
    44881 aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt agccgtctta
    44941 ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt cctccttaga
    45001 ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc aacaagacaa
    45061 agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct cctgtggatg
    45121 tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat gcaccggaat
    45181 tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct acggctaaaa
    45241 tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg atctgctgcc
    45301 atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt cccataacag
    45361 atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg aacaccaaga
    45421 taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca tgtccagtga
    45481 tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag taactgataa
    45541 tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta acgagtcgtt
    45601 tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga ttcaaaagga
    45661 taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga tccgaagaaa
    45721 ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta gccaagaacc
    45781 catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca ggtatgtaaa
    45841 agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct ttataacgcc
    45901 atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa cccctttcga
    45961 ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca aagtataggg
    46021 aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga gtattagaga
    46081 aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag
    46141 ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga gtattaggga
    46201 gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg taacaaaagt
    46261 cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct acggaaataa
    46321 gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct tttcagatgg
    46381 cgctacaact actctgctta ttcttttagc tatccattca attatttttc tctcacttgt
    46441 tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt aggcagccaa
    46501 aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc tttgaccatt
    46561 cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga agtttctgtc
    46621 tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc gccatcaata
    46681 atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct aacctcagct
    46741 agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa caccccgtca
    46801 ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg aaaaagatct
    46861 tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt atcctgagta
    46921 gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg atacgtaatg
    46981 atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt atcgcttttc
    47041 accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac ttctttgcgg
    47101 ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc ccatttcaaa
    47161 agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg tcgtaaacgc
    47221 gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa ataaccatac
    47281 actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa tttgctatct
    47341 tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag cataatcaag
    47401 gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa gcgggctact
    47461 tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat tgtcgccaat
    47521 aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag tttcactaga
    47581 aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg cagcatgttg
    47641 gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat cagtacatta
    47701 cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag taacataaca
    47761 ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct tgtcaatttt
    47821 gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa cccagtagac
    47881 gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt ggcactaaaa
    47941 atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga catgatcttc
    48001 ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac aataataaac
    48061 ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt tattttgttt
    48121 tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa atacaaaagg
    48181 acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt gaccgccgtc
    48241 acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat ataaaaaata
    48301 cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg attgccttgc
    48361 aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact caaagaacgc
    48421 atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg agaggcgatg
    48481 tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc acggataaat
    48541 aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg ttttgcaatc
    48601 gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt gtatcccata
    48661 ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca gggaatgata
    48721 tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc agagcctcgt
    48781 gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt atccatcggt
    48841 cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca gaaactggca
    48901 atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt tcgttttttt
    48961 ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat atcaatgaca
    49021 caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac agttggattg
    49081 aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat cggacattta
    49141 gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa tcttatgatg
    49201 ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt agcgggaagt
    49261 ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc ctcacatttc
    49321 ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt gtacacagtc
    49381 ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt ttttcggctt
    49441 ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa ttattatgtt
    49501 tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc attgtttatg
    49561 aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg gattttgtca
    49621 tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga aattgaataa
    49681 agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac tattaaaaga
    49741 aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac cagaaaaagc
    49801 tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt tgtttttctg
    49861 taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg gtattcaata
    49921 ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa cggatatccg
    49981 taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata aattgaaagt
    50041 gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa aagcaatctt
    50101 ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa cgttagatgg
    50161 caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat atcgtatgat
    50221 gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt cacaagctta
    50281 caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga atatctcgcc
    50341 tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt gcaagcgaca
    50401 attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt ttgatttact
    50461 tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt cggaagaaag
    50521 caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat cttctcatga
    50581 agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag gattcaacca
    50641 agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca gtcaagatgc
    50701 acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga tccaatccaa
    50761 tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa cattgctgaa
    50821 atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca gcccaggaaa
    50881 caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag ctgacatcgc
    50941 ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg aagaaatcaa
    51001 tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc ctgaagcgat
    51061 tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg gaaaaggcgt
    51121 ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt atgcaatcgt
    51181 gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat ttctaagaaa
    51241 aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt ttaacttttc
    51301 actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat catagaattt
    51361 gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta acacagcagc
    51421 tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag gccacggcat
    51481 ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga gtgtagcaga
    51541 agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga ttggcatccc
    51601 gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt ttcctaacac
    51661 tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta aagtcgcacc
    51721 tgatccacca acggttacat aagaattgtt gaattctcct gccaacggat aatttgcgcc
    51781 ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag tgatgatatt
    51841 cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca ccatgacacc
    51901 aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca ttttgaagat
    51961 atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg caatgacaaa
    52021 tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat ctggcatttt
    52081 tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa tcgacataat
    52141 aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca tcctaatacc
    52201 atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac catcagtcat
    52261 gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc ccgtgagcgg
    52321 attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag caaacacaat
    52381 ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt acaagtcact
    52441 aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta atggcaaaat
    52501 atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca tccccgctgc
    52561 catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca tcaggtattt
    52621 ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt ttcatattgt
    52681 ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg atactgtata
    52741 aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg tcctccattg
    52801 ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac tggaatcact
    52861 aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac gttcgtttgg
    52921 tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa aatcagaatc
    52981 atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca ttgcatgttc
    53041 atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa atacatgttt
    53101 ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc ctgcacaatg
    53161 atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc aacttccaat
    53221 aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc catttctatt
    53281 tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc atgaagaatc
    53341 tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt acgcatcgag
    53401 cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat atcaaaagaa
    53461 gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc ttattcgatc
    53521 agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat ttcctgctgt
    53581 acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat tccttcattt
    53641 tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg atcccactgc
    53701 atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg aacagcggga
    53761 tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg ttgctggatc
    53821 tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt ttgcagcaaa
    53881 tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa tttttcagac
    53941 aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat cggtctatct
    54001 gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac atcatcttca
    54061 ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga aagatcaata
    54121 gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata atagcctttt
    54181 acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt taatagttgg
    54241 gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc agctctttct
    54301 ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc attgatggta
    54361 tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa gactttggga
    54421 ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg gctcaatcga
    54481 atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc ctctactaat
    54541 gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt tgatagttcc
    54601 tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt caaataagca
    54661 atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac gatccgctgc
    54721 gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc cttgatttca
    54781 aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt ctgtatgata
    54841 aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat gactagctct
    54901 tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa tgaatttcca
    54961 taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc ttccccttcg
    55021 atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat caatcgctcc
    55081 ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc ttctgccaaa
    55141 tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata cttttgtcga
    55201 tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat ttcttgccga
    55261 ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc ataacctggt
    55321 ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg caagtaatta
    55381 cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt gacatactcc
    55441 ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat tatcatccac
    55501 tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg cctgtaggga
    55561 ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat tctcctaatt
    55621 ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa tcaaaatcac
    55681 tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt acctcttctc
    55741 ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac attcctgccg
    55801 cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta taaaccaagc
    55861 atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg gaaaaaatgt
    55921 gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag aattttttca
    55981 ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa tggacaagcc
    56041 agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg tgcagaagaa
    56101 ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct tttactgatc
    56161 gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat gatggctcaa
    56221 ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt cactgattta
    56281 ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc ttcacttttt
    56341 ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct tatttttcgg
    56401 ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag gatattctca
    56461 aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat tgccaaagca
    56521 ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa agctagacca
    56581 cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa taaaacacat
    56641 ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat cgacatcaat
    56701 ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg ctgaaaaggg
    56761 acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag catccaaatt
    56821 ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt gtctttgttc
    56881 ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa aaataataag
    56941 ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga ataaacaata
    57001 aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact agcggttgcc
    57061 attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga ccatttgatc
    57121 agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc tatgatcgaa
    57181 tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca gaataaaacc
    57241 acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat aaaacaaatg
    57301 gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat gcacttttct
    57361 tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag ttgtagagac
    57421 tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac agtcatctat
    57481 gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt caactatttt
    57541 tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa tcaccacaaa
    57601 ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa ttctgagatc
    57661 aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga agaaaaaaac
    57721 attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt gtggttctgc
    57781 tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg aaaccattgt
    57841 ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc agcgctatac
    57901 ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc caaggcactc
    57961 gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag tgtcgttatt
    58021 ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat tgaaagagtt
    58081 gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga gggttgtgaa
    58141 tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga tggcgagaca
    58201 gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca aactatttcc
    58261 ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac gccacctact
    58321 ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga ttacttggtt
    58381 tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag ctttccgaga
    58441 caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact agagaaaaaa
    58501 ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca ataaacttga
    58561 gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt tttgtatatt
    58621 ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca gcacaaaatt
    58681 gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa tatttgtttg
    58741 tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt gattttaaaa
    58801 actatgctta ttcaattttt tattttagct catatatttc gtttctttct aaattttata
    58861 ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat gatggtttct
    58921 ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct tatatctgag
    58981 ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg ttctttttcg
    59041 atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg agtttctacc
    59101 agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc tcctgtggtt
    59161 agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc tccttgcagg
    59221 acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt aagtcgattt
    59281 tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc gattggtgtc
    59341 gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac tcctggtgct
    59401 aagccgtcaa tcgccagttt tccatctgct cctgtggtta gacctgactg cagaacggtt
    59461 ccattggcat cttgtaactc aaaaacagct ccttgcagga cttccccgct ttggtcatcg
    59521 atctttgtca acacgacacc gcctggtgta agtcggtttg ctttcgtcaa ttctaccacc
    59581 gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg catctaattc atacccc
//
LOCUS       DAIGWC010000007        58435 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.007, whole genome shotgun sequence.
ACCESSION   DAIGWC010000007 DAIGWC010000000
VERSION     DAIGWC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 58435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.007"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..612
                     /locus_tag="NOB74_000453"
     CDS             <1..612
                     /locus_tag="NOB74_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI1219665.1"
                     /translation="KTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQKYVG
                     DNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQE
                     TVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQ
                     LDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(696..1418)
                     /locus_tag="NOB74_000454"
     CDS             complement(696..1418)
                     /locus_tag="NOB74_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCI1219666.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(1408..2145)
                     /locus_tag="NOB74_000455"
     CDS             complement(1408..2145)
                     /locus_tag="NOB74_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1219667.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(2157..3149)
                     /locus_tag="NOB74_000456"
     CDS             complement(2157..3149)
                     /locus_tag="NOB74_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1219668.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(3164..3907)
                     /locus_tag="NOB74_000457"
     CDS             complement(3164..3907)
                     /locus_tag="NOB74_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1219669.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(3981..4085)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(4148..5470)
                     /locus_tag="NOB74_000458"
     CDS             complement(4148..5470)
                     /locus_tag="NOB74_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI1219670.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(5457..6422)
                     /locus_tag="NOB74_000459"
     CDS             complement(5457..6422)
                     /locus_tag="NOB74_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1219671.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(6419..7957)
                     /locus_tag="NOB74_000460"
     CDS             complement(6419..7957)
                     /locus_tag="NOB74_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HCI1219672.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(8373..8660)
                     /locus_tag="NOB74_000461"
     CDS             complement(8373..8660)
                     /locus_tag="NOB74_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219673.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8794..9462
                     /locus_tag="NOB74_000462"
     CDS             8794..9462
                     /locus_tag="NOB74_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1219674.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(9753..10493)
                     /locus_tag="NOB74_000463"
     CDS             complement(9753..10493)
                     /locus_tag="NOB74_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219675.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(10623..11570)
                     /locus_tag="NOB74_000464"
     CDS             complement(10623..11570)
                     /locus_tag="NOB74_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1219676.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(11699..12463)
                     /locus_tag="NOB74_000465"
     CDS             complement(11699..12463)
                     /locus_tag="NOB74_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI1219677.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(12467..12856)
                     /locus_tag="NOB74_000466"
     CDS             complement(12467..12856)
                     /locus_tag="NOB74_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219678.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            12991..13533
                     /locus_tag="NOB74_000467"
     CDS             12991..13533
                     /locus_tag="NOB74_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HCI1219679.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13681..14313
                     /locus_tag="NOB74_000468"
     CDS             13681..14313
                     /locus_tag="NOB74_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219680.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(14447..14572)
                     /locus_tag="NOB74_000469"
     CDS             complement(14447..14572)
                     /locus_tag="NOB74_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1219681.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(14706..15599)
                     /locus_tag="NOB74_000470"
     CDS             complement(14706..15599)
                     /locus_tag="NOB74_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HCI1219682.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(15781..16707)
                     /locus_tag="NOB74_000471"
     CDS             complement(15781..16707)
                     /locus_tag="NOB74_000471"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HCI1219683.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(16792..17553)
                     /gene="pflA"
                     /locus_tag="NOB74_000472"
     CDS             complement(16792..17553)
                     /gene="pflA"
                     /locus_tag="NOB74_000472"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HCI1219684.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(17797..20028)
                     /gene="pflB"
                     /locus_tag="NOB74_000473"
     CDS             complement(17797..20028)
                     /gene="pflB"
                     /locus_tag="NOB74_000473"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCI1219685.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(20305..22755)
                     /gene="parC"
                     /locus_tag="NOB74_000474"
     CDS             complement(20305..22755)
                     /gene="parC"
                     /locus_tag="NOB74_000474"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HCI1219686.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(22767..24812)
                     /gene="parE"
                     /locus_tag="NOB74_000475"
     CDS             complement(22767..24812)
                     /gene="parE"
                     /locus_tag="NOB74_000475"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HCI1219687.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(24978..25412)
                     /locus_tag="NOB74_000476"
     CDS             complement(24978..25412)
                     /locus_tag="NOB74_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HCI1219688.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            25539..26177
                     /gene="plsY"
                     /locus_tag="NOB74_000477"
     CDS             25539..26177
                     /gene="plsY"
                     /locus_tag="NOB74_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HCI1219689.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(26309..27184)
                     /locus_tag="NOB74_000478"
     CDS             complement(26309..27184)
                     /locus_tag="NOB74_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCI1219690.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(27266..28057)
                     /gene="codY"
                     /locus_tag="NOB74_000479"
     CDS             complement(27266..28057)
                     /gene="codY"
                     /locus_tag="NOB74_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HCI1219691.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(28075..29475)
                     /gene="hslU"
                     /locus_tag="NOB74_000480"
     CDS             complement(28075..29475)
                     /gene="hslU"
                     /locus_tag="NOB74_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HCI1219692.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(29489..30037)
                     /gene="hslV"
                     /locus_tag="NOB74_000481"
     CDS             complement(29489..30037)
                     /gene="hslV"
                     /locus_tag="NOB74_000481"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HCI1219693.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(30074..30979)
                     /gene="xerC"
                     /locus_tag="NOB74_000482"
     CDS             complement(30074..30979)
                     /gene="xerC"
                     /locus_tag="NOB74_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HCI1219694.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(31177..32553)
                     /gene="trmFO"
                     /locus_tag="NOB74_000483"
     CDS             complement(31177..32553)
                     /gene="trmFO"
                     /locus_tag="NOB74_000483"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HCI1219695.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(32522..34600)
                     /gene="topA"
                     /locus_tag="NOB74_000484"
     CDS             complement(32522..34600)
                     /gene="topA"
                     /locus_tag="NOB74_000484"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HCI1219696.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(34722..35579)
                     /gene="dprA"
                     /locus_tag="NOB74_000485"
     CDS             complement(34722..35579)
                     /gene="dprA"
                     /locus_tag="NOB74_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HCI1219697.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(35635..36402)
                     /locus_tag="NOB74_000486"
     CDS             complement(35635..36402)
                     /locus_tag="NOB74_000486"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HCI1219698.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(36395..37255)
                     /gene="ylqF"
                     /locus_tag="NOB74_000487"
     CDS             complement(36395..37255)
                     /gene="ylqF"
                     /locus_tag="NOB74_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HCI1219699.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            37515..37913
                     /locus_tag="NOB74_000488"
     CDS             37515..37913
                     /locus_tag="NOB74_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI1219700.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            38192..38692
                     /locus_tag="NOB74_000489"
     CDS             38192..38692
                     /locus_tag="NOB74_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCI1219701.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(38775..39326)
                     /gene="lepB"
                     /locus_tag="NOB74_000490"
     CDS             complement(38775..39326)
                     /gene="lepB"
                     /locus_tag="NOB74_000490"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI1219702.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(39478..39705)
                     /locus_tag="NOB74_000491"
     CDS             complement(39478..39705)
                     /locus_tag="NOB74_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HCI1219703.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(39702..40220)
                     /gene="msrA"
                     /locus_tag="NOB74_000492"
     CDS             complement(39702..40220)
                     /gene="msrA"
                     /locus_tag="NOB74_000492"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI1219704.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(40240..40953)
                     /locus_tag="NOB74_000493"
     CDS             complement(40240..40953)
                     /locus_tag="NOB74_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HCI1219705.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(40956..41852)
                     /locus_tag="NOB74_000494"
     CDS             complement(40956..41852)
                     /locus_tag="NOB74_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI1219706.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(42010..42852)
                     /locus_tag="NOB74_000495"
     CDS             complement(42010..42852)
                     /locus_tag="NOB74_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI1219707.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            42984..43637
                     /locus_tag="NOB74_000496"
     CDS             42984..43637
                     /locus_tag="NOB74_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HCI1219708.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(43700..44227)
                     /locus_tag="NOB74_000497"
     CDS             complement(43700..44227)
                     /locus_tag="NOB74_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI1219709.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(44247..45194)
                     /locus_tag="NOB74_000498"
     CDS             complement(44247..45194)
                     /locus_tag="NOB74_000498"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HCI1219710.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(45206..47092)
                     /locus_tag="NOB74_000499"
     CDS             complement(45206..47092)
                     /locus_tag="NOB74_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI1219711.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(47252..49330)
                     /locus_tag="NOB74_000500"
     CDS             complement(47252..49330)
                     /locus_tag="NOB74_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HCI1219712.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(49343..49618)
                     /locus_tag="NOB74_000501"
     CDS             complement(49343..49618)
                     /locus_tag="NOB74_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219713.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(49980..50435)
                     /locus_tag="NOB74_000502"
     CDS             complement(49980..50435)
                     /locus_tag="NOB74_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219714.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(50589..51797)
                     /locus_tag="NOB74_000503"
     CDS             complement(50589..51797)
                     /locus_tag="NOB74_000503"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HCI1219715.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(51909..52241)
                     /locus_tag="NOB74_000504"
     CDS             complement(51909..52241)
                     /locus_tag="NOB74_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCI1219716.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            52389..53264
                     /locus_tag="NOB74_000505"
     CDS             52389..53264
                     /locus_tag="NOB74_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1219717.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(53346..53927)
                     /locus_tag="NOB74_000506"
     CDS             complement(53346..53927)
                     /locus_tag="NOB74_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HCI1219718.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(53933..55192)
                     /locus_tag="NOB74_000507"
     CDS             complement(53933..55192)
                     /locus_tag="NOB74_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCI1219719.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(55194..56240)
                     /locus_tag="NOB74_000508"
     CDS             complement(55194..56240)
                     /locus_tag="NOB74_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219720.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(56475..56750)
                     /locus_tag="NOB74_000509"
     CDS             complement(56475..56750)
                     /locus_tag="NOB74_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HCI1219721.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(56993..58303)
                     /gene="der"
                     /locus_tag="NOB74_000510"
     CDS             complement(56993..58303)
                     /gene="der"
                     /locus_tag="NOB74_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HCI1219722.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
BASE COUNT        16081 a        12246 c         9987 g        20121 t
ORIGIN      
        1 aaaactttac tttttggaac aactttggct gccggcgctg cattcttcat gggaacgact
       61 gctcatgcgg acgaagctta taccgttcaa tcaggtgata ctctatcaac gatttctcaa
      121 aaatacgttg gtgataactc cttgatcaat gccattgcag aatcaaattc aatttctgat
      181 attaacctga tttactcagg acaacaatta acaatcccaa cagaaggctc tgcacaagca
      241 gctgctgaac ctcaagcagc cgttcaagaa gcaccagtcc aagctgaaca acctgttgta
      301 caagaaacgg ttcaaacgga aaaacaagca gcgcctgttg ctgaaacaca acctgctcct
      361 gctgtaacag aaactgctgc tactccagca agcacaagct ctgcaaaaga atggatcgca
      421 caaaaagaat caagcggttc ttacacagca acgaacggac gttacatcgg acgttaccaa
      481 ttagattctt cttacttaaa tggtgactac tctgctgcaa accaagaaag agtagcagaa
      541 caatatgtta cttcacgtta tggttcttgg gaagcggcga aagcattctg ggaagcaaac
      601 ggttggtact aagattcatt tattaatcaa acagtttact tttatacaaa gaaagccaaa
      661 aagaggtgcg acactagttg tgtcacatct cttttttatt tacctaatct aatgaaacgt
      721 tccaagtttt gataagtatt ttttttaact tcttcaactg atagctcttt gatctcagcg
      781 attgtcttta actgttcttc aagcagtgag acataatctt tttctgaaaa aatcccccct
      841 aaagcccact ctgctgcatg tagtccatcc gtttcaataa gtaagtggtc gattgggact
      901 gctttagcta gttgccagac tgctggattc tttttcaaat caagaccaat gctgaaataa
      961 cagcctaaat caatatagtc ttgttgatag tccaaagaag aataccaatg gatcaaatag
     1021 tgattagggt aagcttggat ataatttaag atctcttttt cgcatccttt tgtgtgcagt
     1081 acaacaggtt tctcatttat ggctgcaaaa gcaagctgtc gctcaaatac ttttttttgt
     1141 gtagtcatcg gtacattcgt ccaaatatta tctaacccta tttcaccgat gatccttgct
     1201 tttttcaaaa aaggctcaac ttgttcaaac gtatagctat ctgctttcca aggatggata
     1261 ccgtaactta aggcttgagt cttacttgct gcaagctgtc tgttttcctt ccattcttct
     1321 ggcgaatcac aattgatgat cgtcaaaatc gtgtgttcct gctgaaggag tgctaaactc
     1381 tgactcccat ctaaatgaca atgagcatca cttaacatct aattcacctg ccaataactg
     1441 ataaatcgtt tgcttcaact ctgattgctg cagtagccat tcacgtgacc gtcgtttttc
     1501 aggcacttga atctcagcaa tcacatgtgc cggacgggcg gaaagcacaa gaatcctgtc
     1561 tgataaataa attgcttctt cgatatcatg cgtcacaagt aaagtagtcc gctttgcttt
     1621 tttaggcagc ttcaacatcc agtcttgcat ctgccctctg gtcatagcat ctaacgctcc
     1681 aaatggttca tcaagaagca agtaagaaga aggattcatg attgttcgta acaaggccgt
     1741 tcgctgcttc atcccgccag ataattgttc cggcaaaaaa tgttcatagc cgtttaaccc
     1801 aaagatatcc agataatccc ttacttgttc ttcattgatt gttagatgat tgattttttg
     1861 atataacgta acgttttgat agacgctcag ccaaggaagt aacatatctt cttgcggcat
     1921 ataactaaat gctgtatgga gaccagttac tttttgatcg tctactttga tcgttccaga
     1981 agtcataggc tggactcctg ttaaagtttt cagcaatgtt gacttaccgg ctccgcttgg
     2041 cgcgacaatc gatgtaaagg tatctttagg gatagtgaaa tggatgtctt ctaatatttt
     2101 caggttttca atgactacat tcaagtggct gatttggatt gacatatcta tcactcctat
     2161 tttataaact gattagtgaa tagttcttgc gaaggtacat cttgcttgat caatccgttt
     2221 tcctgcataa aagctgtata attgcgccaa actttttctt ccatcaatcc ccaattctca
     2281 ggatcatccg tataattttt tgacaagaat gcttgtgatt cttctaaaaa cgtccgatca
     2341 ttttcttttg catatttttg caacagttta gcactgtcat ttggatcctt aatagcttcc
     2401 tgatagcctt ttttcgtggc atccataaaa gactgtacca attctggatc acttttgatc
     2461 agttgatcat tcgtaataat taccggagta tagtaatcta accgttcatc taattctttc
     2521 aatgggatat agtttagttc aatacccgct tcttttgctt tgatcatatc ccaaccttca
     2581 aagtaccatt ggatatctga ggattttcct aagctttctg gcccttctcc attgcttcct
     2641 accattgtca gttttgaaaa gtccccgccg tctttttcca tcacagcttt taagacagct
     2701 tcttcacttg gactttgcca acctgcatat gtttttcctt caaaatcttt tggtgaatgg
     2761 atgttactgt ctgatagggt ggcgaatcca gaagtattat gtttgatcac tgtagcaatt
     2821 gctttgactg gtatattctg tccatctgcg tgagcataag tgacatcttc ttgataactt
     2881 acaccaaatt gtgctttgtc cgcacctact agaccaatac ttgtcgaatt atctcctggt
     2941 tcgatgattt ggacatttaa accagcctct ttataatagc ctttttcttt tgctaggtag
     3001 atgccagtat gattagtatt cggtacataa tccaaaacaa gtgtcacttt tttcaaatcc
     3061 tttatttctt gtttgctact tgtttctttt gcagtgccac aagcggataa aagcaacagt
     3121 agcggtaata aaagccataa ttttttcatt tgatcccctt ctcttaaaaa atataaagca
     3181 tacgataata cccttttttc aataatgaac aagcgccatt cagcaataaa ctcaatagaa
     3241 tgacacaaat gatcgcagca aaaactttat cgatctggta gctgtttttt acgcgtatca
     3301 tgtaataccc taagcctgct tgagcgctta gccattctcc aacgactgct ccgctgacac
     3361 aataagtagc agccactttt aaaccggaaa agaagccgga taaacccgct ggtattttat
     3421 atattcgata aatcttccct gtatctgccc ccatcgtttt caaaaagatg atttgctctt
     3481 ttgatacttt cctcaatgta tccgaaaaag aaactacgat cggaaaatag cttatcaaga
     3541 caacaaggat cacttttgga agcataccga aaccaaacca tagggtaagt aatggcccta
     3601 acaccatgat tggcaacatt tgtgaaatca ctagtaacgg ataaaaagac atttctaaaa
     3661 acttccaata atccattgcc aaggcagtaa taaaagaaag aacgctagct attaccaaac
     3721 caagcactgc ttcatttaat gtcgtgacag aatgggaaag taatacttgt gcatctgccg
     3781 ctaatgcaga aaatacagca gcaggtccgg gtaaaataaa ggcaggtatt ttccaaacta
     3841 tgacaacaat ctgccaaata attaaaatga atgccatact gactgctgga taaagatttt
     3901 tcttcatttt gttacctcct ttcttctaat atgaataaca aaaaacgctt gaaatgggca
     3961 cgacatagta acccgcttca agcgtctgct atgtttctcc cttcaccagt attaactgac
     4021 aggttcaatg ggtctaagtt cacaacttac tctcatgtcg tctacgacat ccccagaaac
     4081 aggtattcat tttttaaagt gtagcacaag aaggaaaaag caacaagcgc tttagttatc
     4141 atgctgatta tttcaataaa taggagagat cacttgccaa tgtcggatac cccatgatat
     4201 agctatccaa ctctttttta gtcaattttt gattgatgac gagtgtcaaa tcatcgatca
     4261 attcgtctgc ttgctcgcta atcactgcag caccaatcaa ataattttgc tggtcaaagg
     4321 tcaattcagc cttagcaact ggttcattga cacgatgata ggtgaaccaa ctggtaagat
     4381 ccatctctac cacttgatct gacgaagagg cgtgactttt tgtaactcct acttcagcaa
     4441 gtttaggact ggcgtagacg atcgtaggta taatcggata tttgataggt tcgcttgttg
     4501 catccgttat ccgcttagct acataatttc cttcaaaagt ggcgactggt gtcaattttg
     4561 gggttttcct tgaaacaata tctccacacg caaaaatttt tggattgctc gtttgcagat
     4621 aatcattgac tgcaattccg tgtttatcaa agacgatatt cgcttgctca agtgctaaag
     4681 attctgtatt cggctgtctc ccagtcgcac aaaaaatcat atctgctact aattccgtct
     4741 cttttccgac taaacgatag cgagtacctt ctgaaatgat cttttgggtt tcaacaccaa
     4801 aagcaaactg aatgccagat gcttccattt gatggacggc ttcctctacc aaagacgcct
     4861 caaattcttt taatggccgt tgattatgat ggacaatggt tactttgctc cctgcagcat
     4921 tggcaatcgt agctagctca aaagcaatat aaccaccacc gataaaaatg atttctttag
     4981 gcagtacagg caatgataaa aagtctgcac tagttttcaa gtattccttt ccctccactg
     5041 gtaagatcgt aggtctttgc ccggttgcca aaactaagta atccgcatgg aagacttctt
     5101 cgttgacttc aatagatgaa tcatccaaaa aacgagcggt tcctgaaaga tgatcgattt
     5161 cagcttctgc taattgtttt tttcggcttt ctgggactgg atccgtaaat gttcgtttga
     5221 atttttgaag ttcttcccag ttggcagttg ggatctcgtt aaaacctttt ccactcaatt
     5281 gttttacccg attacgtgcc tctactgcac ttaacaagac ttttttagga tcacatccac
     5341 ggttaggaca agtcccgccc catagatctt cttcgaccac tagtactgtt ttacctgctt
     5401 ctttcaatcc ataagcagca cttaagccgc tcacacctga accgatgatg attgcatcat
     5461 atgttttcat ttccttcctc ctctcgactt aaaaaagcaa agatttcttt acttgtcagc
     5521 gacccaatac ttctttgctt ttctactatc acaatgcttg gatacaccga aagaagcgaa
     5581 tatacttctt tcataggcgt atcaaagcaa acttgttgac gagcattttc tggtatttca
     5641 tttaagaaat atccattgac gactaaatct tctactcgcc actctttcgt ctgtttcggt
     5701 tcatcaaaga aatgccgaac gtagtcgttt ttaggattca tcaataactg ctctggtgtg
     5761 tcacattgga taatttctcc atccttcata aatgcaatac gatcacctag cttgattgct
     5821 tcttccatat tgtgcgtaac gaaaacgatg gtcgtgccca attcttcgtg taaggacaaa
     5881 accaattctt gtaatgagtt tcttgaaatc ggatctaatg cgctaaatgg ctcgtccatc
     5941 aaaatcacat ctgggcttgc agcaatagct cggatgatcc cgatccgttg ctgttctcct
     6001 ccagacaact ctctaggcat acgatctcga taaatatcag gagataagcc aactttttga
     6061 agaagttcat ctacacggtc tgctcttttc tgcttttccc aacctaacat ttcagggatg
     6121 acttcaatat tttgcttgac tgtcatggtc gggaacaaag cgatttgctg cagcacatat
     6181 cccatattcc accgcatttt ctgcagatta tattcattta acgattttcc tttgaagtag
     6241 atgtctcctg ctgatggttt agataatcca ttgatcattt tcaaagtagt tgtttttcca
     6301 ctaccggaag gaccaaccaa aacaaagatt tctccttttt tgattgccag atttaggtca
     6361 tcgatgacat actttccatc atactttttt tgcacatgtt tgaactcgat taatttagtc
     6421 actgatcttc ctcctttact aatccttcat ttttcaggaa gattcgtgct acttctgtcg
     6481 gctttttctt ttcgacattg acttggtaat tcatatcaat catttgatcc tctgttattt
     6541 ttccgcttaa tttattcagt gctttaacga tttcaggatg ttctttagca aaatcttttt
     6601 tcatcagcgg tgcgccttga taagctggga ataaccctcg atcatcttct agagtcacta
     6661 gatcgtactc cttgagctgg ctatctgtgg aataggcatc cacaatattg acatctccat
     6721 tattgattgc ttggtaacgc aaacttggct ccatgctttg tacacttgaa aaattcaagc
     6781 catatgcttc ttggattcct ttatatccat ctgaacgatc aataaattcc agtgtgaatc
     6841 ccgctttgat ctgatcagag atagctgcca aatcggaaat ctttttaagt tgatgttcgt
     6901 tcgcaaaaga tctcttgact gccaaggcat acgtattttg gtaagccatt ggttttaata
     6961 atgtcatatc gaattgctta ttcaataatt cttctgcttc gtcatatgtt ttttcttttg
     7021 tcaaatcagc acttttcatt gcttcaggta ccttcaccaa gctttctagg acagtacctg
     7081 tgaactcagg atagatatcg atttgacctt gatccagtgc attgaacaaa aaactcgtct
     7141 tgccaaaatt cggttttaat tcaacttctg tttttgtgtt gtcttcaatc aattctttat
     7201 acatttggat caggatttca ggttccgctc ctaattttcc agcaatcgtg atggtttcat
     7261 ttttaaacaa ggcagactga tataaagaaa cgccgccaaa taaacacacc actgctgcta
     7321 aagtaatgat ggaatatcga ggtttcttat gctgcaacca gcgaatcagt ccgctgaata
     7381 taattgcaag caaggcagaa ctgatcgcac caatcaatgt caaaacaggt gtatttcggt
     7441 caatacctaa caaaataaat gtccctaatc cacctgctcc gatcaatgct gccaaagtag
     7501 ccgtaccgat gattaaaact aaggcagttc ggatacctga gataatgaca ggtaatgcga
     7561 tgggaagctc tactttcagc aagcgtctca ttctggacat accaaatgct accgctgctt
     7621 cttcaataga cgggtcaatt tcagctagac caatatacgt gttttggaaa atcggaagca
     7681 aagcgtaaat aacaagtgca atcaatgctg gaacagttcc gatccctaca aatgggataa
     7741 gtaaacctaa taaggcaagt gaaggaatcg tttggagcac acccgtgatc tgcaataaga
     7801 cttctgccat ttttttatga ttggctgccc aaatcgctaa aggaatagca atcagtgctg
     7861 caatcagcaa agaaatgaga gaaatggaca gatgttgaaa tgcagcttcc agcaactcgc
     7921 cttttctttc acttaatgtt tgtataaaat tattcatgcg accttccttt ctgttattct
     7981 ttaagtataa acatttcttt cctttttccc aactaacttg tcttgcctta accttacagc
     8041 acgaacaaaa aaaagaaaaa aatacctcta aatatgctga caaaaaaaga atccaagcaa
     8101 caaagtcgga tcaacttttt ggttctcgtt ttttcactac gaataccata aaaatctata
     8161 cgaaattgtc acttggaatc agctatatct tttttacaca cacaactttt attttaataa
     8221 aaagaaacag ccaataaagt agaaatctcg tgggggagaa cacctttatt ggcctgttca
     8281 acgaatatta tactgtatca tgacactttt ttgccaaaaa tgtaaaaaat ggttgttttg
     8341 acatcataaa cgtcttgttt tcttattttt acttatatca ccactttatt ttctatctct
     8401 ttcactccat aaagaggaat gagttcttct tttgactgat aataaacagc tttctcacgg
     8461 ttcttcatca aaaaaagaaa gatgtctttc atagcaagtg gtgctttgcc gtgttcaaat
     8521 aaaaagataa attgatttgc tttatttatc tggaccattg tcacaggcac cagtttttgt
     8581 tcttgagcca aaaaaactcc ttgatactct gtttttttgg gtgattttgt aagaattgtc
     8641 aataagtctg ctgctcgcat ttttccactc cttatttgat aaataaaaag aaacagccaa
     8701 aaataatttt ttttcatttt cctcttgaag taagagtata agtcagtata ataaagaagt
     8761 tgctgaaaat tttcaaaaga aaagaggcta gaaatgaaaa aattaaattt atttacagaa
     8821 ttgtgcggaa tcattttagg cgcaggaatc tacggattag ctgtgacagg aatcaatatt
     8881 ccatctaagc tggcagatgg tggggttact ggtattgctt tgcttttgca taatcttttt
     8941 ggattcgctc cttctgtcac ttcactgctt tttaatttac ctttattgct tatctcattg
     9001 tttctttttg gaaaacacgc ttttctccgg acgatcgtcg gaacatttgc gctagttttc
     9061 tttttacatt tatgggagag ccttcatata cattttgctg tagatagtct actgatcaat
     9121 agtttgatga caggtattct ttctggcatt ggttgcggtc tcgtctttcg attcggcgga
     9181 agcacaggcg gaacagatat catttatcaa gccattgaaa aatattttca tattaagatt
     9241 ggcaaaagtc ttttcttgat tacttttggt attttagttg tctccttgct ttatttggat
     9301 ctcacacatt ttctgtatac attacttagc tgttctattc tatcttatac attgaataaa
     9361 gtgaagtatc tggaaattgg atctgttttg ccccaattgg aagcaaaaca gactacagaa
     9421 acatttgaac cacttgatcc tcttgaacag ttagagcact gattcttatt tttcactact
     9481 ttatttaatt tacagaaata tcattatgta aactaaaatg atattattca gtaaaatctt
     9541 ctttataaaa aaataaacta tttttgcaaa cgatctgcga aaatagtttg tttttttatt
     9601 ttgccattat tttcttactt attgggagaa aaaattcgct taaactcaaa aaaatttgag
     9661 gatacgatat aaactttcgg atagagtata aaataaggaa acgccgcagc gtttcctttc
     9721 caactgtagc cgaatataaa tttgtatatc acttatttaa aatagctatt ttctcccaaa
     9781 gagtttcctt gatcatcgat caatccttgt aatgagcgtt ctaagatacc atggcttttt
     9841 ttcgattttt tttcttctga ctgctttgtt tcctctaacg tttttgttcg attgaatgtt
     9901 cgtacagacg gctcaccatt tcttttttct tgatacggcg tcggttctgt atcgaacaac
     9961 agataagagt catccgtttt tttcatcgat tcgattaaat gatcctcaga aattttgctt
    10021 tctctagggt ctgggataat cgatgcgggt acatatttag gaacaaaata agaacgctcc
    10081 cgcaccttcg tgtcaacaga tgcgtttcgt gtagtatgct tggactctgt ccttgtttca
    10141 ctttgtctga cagaacgaga ggaatcacca aaaagttttt ttcgtcctgt cgatgtgatt
    10201 tctgattggt aatggccggt ataatccggt aattttcctt tatgcttttc caaattttcc
    10261 ttacgcggag ctgacttcaa tccatttgtt gcacgacgct tgcgacggat tttctcggtg
    10321 ttcgtgttcg tgaaatgaaa ttctttcatc tgttcaaacg gggactgatt ctgttcagtc
    10381 aaaagatctt cttgtccgtc aaataatact cgcttcttgt cgttggttaa ttttacgcct
    10441 aactcatcat cgtacgcagg aaaacggaaa tgttttcgtc tgatttcttt cattcaaacc
    10501 atccttctca aaaatggaac ttttctcaat aatagcacag attcattgtt ttcagtagca
    10561 atgcgctgat tattttaaga aaatagcgat gaatttcata aatatatata tagtaataag
    10621 acttaattcg ttgtctctct gataactagt tcaggaaaaa aacgacgata accttgactc
    10681 gccccttttt cttctatttt ttttaacaac atttctccac atacttcacc catacgtata
    10741 atatcttgct tgatcgttgt caatttaggt gaactgattt ggtctaaaaa taccccatca
    10801 aatccaatca caccaaattc ttcgggcaag tgtcctccag catttataat ccctcttact
    10861 gctcctagtg ctagccgatc tgaactacat acaaaacaag ttttatctgt aaaatctgcc
    10921 cagttttctg tcatatatct ttctacttct gtcgaatgat ttggaaaccg caagatttta
    10981 ctaggaagat caacttcctt catcacagat aaataaccag tttcccttga aatttcaaaa
    11041 ggctcgtcca cttcgatacc gatataaata atcgtttgat aatctctttc taaggcatat
    11101 tgcgttgctt ttgctgtacc atattcatta tcgctgtcta cataatcata tccttcagaa
    11161 ttttccccaa acaagacaac tggtttttcc aaacggtcga tccaatcgaa gtcttttttt
    11221 ctgacacctg tgatgatgta tccatcacaa gaaccgacgt cgaaggcatc atttgtaact
    11281 aattggagag aataatgcgc tttaccgatc cgtttagcga ttcccatcag caaattcatg
    11341 taatagggct cagttgtgtc gatttcttcc agtataaata atttgatgat ctgcgaccga
    11401 ttcgtgacaa gtgcttttgc agcaatattt ggacggtaat ccagttcagc cattgctgag
    11461 aaaactaact ctttcaattc gtcagtcacc tgttccggat gattgatgac tcgagagacc
    11521 gtcatttttg aaacattggc acgttttgca acatctgcta aagtgggcat gctctcttcc
    11581 tttctaacat gttgtcattc ttactatcaa ttataccaaa ttttcctaac agagtttatt
    11641 atagcccaaa ataaaaaacg gaaaatcctc tatcgtcatg agtgattttc cgtttcaatt
    11701 atttatactt ttttatcaaa ttttttgcta aaaaagtgga agcttcttcc attagtggta
    11761 tttgtaccat atgtcgctgt gtttttgagg aacgaaaaac aatttctttt ccgtaagact
    11821 tatgccgatt tttttctaca aatcgttccg tttgtatata agggattttt tcgtcagctt
    11881 gtccatgcca aaagaacaga ggacgtccag ctaacttttc cggctgcaat gacaaatcat
    11941 agctcttaac ccatgaaatc aaatcaaaat agtcttttgg tacgacataa ttatattccg
    12001 atgcgcgcct tacgatttct tttccatatt ccaaaggtgc aggggaaccc atcaaacaca
    12061 cgcccgctac tatatgagga tgtttagcca acaaggcgca tgttgtcatt ccccccatcg
    12121 aaaccccgcc aactgcaagc tgatcatgta gaagacctct tttttctaaa tgcttgataa
    12181 gtgtgtcaaa ttcaaacaga tttccgtaga tactatccca aaatgtatag gatggaatag
    12241 aagaaaccgg ctgtttgcgc tccccatgat tcatcgcatc tggcaggatc acacgaatgc
    12301 cctgctgcgc aatttttctt ccttgcgtca aaactaactc cttacttgtc tgccatccgt
    12361 gataatagat gacaacggga atacgttcct ctcttaattc tttcagaaca acttctaaca
    12421 ctggaatatg atggacagaa cgtttcaata taattggatt caattgttac tcacctattt
    12481 tcattaaatt tcctgatcgc catagcaacc atgctccaac agttgtctgg aacaggttca
    12541 gtgtaccaaa taatataaat gcaggactga atggctcggg aaataagcac agagaacaaa
    12601 gtcccaccac tcctaatgct agcgaaagga gtggataaat agaaaaattc aaaaaactgg
    12661 caacgctacc gaaaatatta ccaataaaca gtatcaaaaa gaaaaaaacg cttaaaatta
    12721 aaccatctgt cagcgacatc tgaaaaacaa tgttctctac ctcaattggc tgttgaatcg
    12781 aatagacacc taagtatata ctgagaagga gacttagcac gtggctggca caaaacacac
    12841 gattgaccgt tttcatttta atcacctaac ctatctttat aattctatta taatcatttt
    12901 atcatttttt tgtatgtata aagtttcaat ttttcttcac ttacgatttt ttttgatatt
    12961 gttgttatat aaatgaaagg agttttacaa atgattgatc caaaaatgtt ggggatgatc
    13021 ttcctcatta attttgctta tatcactctg aacacgttac gtttcatgtt gacaatgaaa
    13081 ggctatcgac tgattgctcc acttgtcagt atggtcgaga tcacgattta tatcgtcggc
    13141 ttatcccttg ttttagatcg tttagataat ccactgaatt tatttgtcta tgcgttaggt
    13201 tacgcagtag gtatcagtgt cggaattttg attgaagaca aattggcatt aggatacatc
    13261 atggtcacaa cgattttgcc agcaaatagc gcagaagata aaagtttgcc gggtatactg
    13321 agagaacacg gttatggtgt gacacagact tctgcaatgg ggctggaagg tgagcggcta
    13381 gttctcgaaa tactttctcc tagaaaaagc gaacgtgaac tgtatcgcct gatcaaagaa
    13441 atcgaagagc gtgcttttat catttcttat gagccaaaat atatttcagg tggtttctgg
    13501 actaaaaaag tgagaaaacg acaaggaaaa taactcacaa acttaaaaac tgtctaatat
    13561 ctaaattaaa ttttaaatgt tagacagttt ttatttatta ttttgattaa aaaacatcga
    13621 catatactca tcaatttgtt attatacttt atatacttat caatttaatt tggagatatt
    13681 atggaaattc aacgtagaac cactaatttt ttacatttag gctctttttt tgcaactttg
    13741 acgatcttat tttttctatg ttattcatac cttaagacct cacatgcgcc ttctagtgca
    13801 ttaggctggt tgcttttgga tcattctgat atcacagaag ccgaagaaaa tccgtttttt
    13861 ttgattttgt cttctctttg cggcttactg ttttctgttt atttcggtgc ctattttttt
    13921 catcgacatc ctggtacgtt aaacgaagct tcaagcgtat tgattgcatt taaaacgttt
    13981 tcttttttag caattctttt ttattcgttt aatcacaata cgcttttctt ctttatcatg
    14041 aatggtttag tcgtgatttt atccattttt acttatttta ttttttcact catttttagc
    14101 caattgaaat gtccgctctt ctttcgatta gttcctgtca cctgttttat ttacagcttg
    14161 ttttcctttt ttgtccttgc tttaatgcca ctgaccaacc cttcgacgat ccaagtcgca
    14221 ggaaatctgt tggatatgct cttcatcgtc agtctaggtg tatttatgtg gcaaagaaaa
    14281 aacaaacaaa ataaaaagca ttttgaagcc tgactattac gacttcataa atgctttttt
    14341 agttttaaac acttcaatct aaaagaataa cccaagattg gataaattat taatgactcg
    14401 ccattcgttt cttagtgatt ctggattatc aaatggactt cctaatctaa tcagctagtt
    14461 cttcccataa aatgccatac ttgactgaat cataatattg attatttaaa aatctaactt
    14521 ttcttatcac tacttccttt gtcattccac atttctcacc atttttttgc attcctttgt
    14581 ttccagacca tgtagtgaat ctaataggtg gtagataggc aaaatactca aataattctt
    14641 ttaaccataa aggaagagaa aggctcctcc tgcaagagtc agtataattt ttgcttactg
    14701 ctctcttagg ttttactcac taaaactgtt ccatattctt tgatataaga aaatgcatgc
    14761 ggtataaatt tcttgctcag ctcagaaaag atttgtcgtt taagaaaggc catttcctcc
    14821 attgtcaatg aaggatccaa tgttggtaat tcaatctcaa aattgttttt ttcgacaata
    14881 ggtaattcta atgtgaatga ttcttcttcc tttatagtat tcgtcacaag tagagactga
    14941 tggaaaatac taggccggcg atttttatat ttattcttac gtatcctgtc aacgataact
    15001 tctatttgat caaaaaagta cgattcattt acgtctccaa taagttcggc taattctttg
    15061 aatgccttcg ttacaggaag ctgattcttc tgtacaaaaa agtaattagc caaagtaagc
    15121 gggaagtgtt ctatagagga aagtgtgata aaacggtact tctcatttcc tgcagttgtc
    15181 ctcagcaatt ctgtctctcg gctgtttctt actccataaa aatacgcttc tttccgttca
    15241 tcttcgaaac aatacgccca aataacttct cccatcgcta atttttgttc atcaacagag
    15301 agtctcttca attgttcagc tatggtttca gcagccgaag tggcttgttg caagtaatct
    15361 ttaggatcaa atattggaaa gttcaaatga tatcttcgtt cttccctctt gattaatcct
    15421 gcatcgatca ataaatcaag aaaatgggaa aatttatttt gcgaaaattc ttttttcaat
    15481 tctcttagaa tcgtttcttg ttctcgatgt tcatatagat aatcggtcaa tgaagaaaaa
    15541 agcggatcat cggtcagttt ttgataaaag ttttccttat tttttgaata atagttcata
    15601 tatgttctct tttctatccg ttttatttta cttaaaaggc ttttacgtaa aaaggaggaa
    15661 gaacaagagt cataattgac tgttattctc ctccatttct tcggccttta gtatgttcta
    15721 tgtttctttt tatatcaatc gcttatccat tcattttgaa tgcttcatac taccatttga
    15781 ttagctaaat acagccgtca attgaggtac gacttgtttt ttacgtgaaa cgacaccttt
    15841 aagcaaagca cggttgttgg tcaaagttgt ttggaaagct tcttctactt tttcttttcc
    15901 tttaccagca acaagtaatt ctgaatcact gtctaagatg tttgtgacaa ctaatacgaa
    15961 cagatcgtag ccatttgctt tcatttcatc ttccattgct gcttctagct ctgcttgtcg
    16021 atccatcact tcattaaggt ccactgtatt gacttgagcg atacgaacgt tggaactgcc
    16081 cattgggaaa ctttttgcat ccaaatcaag aagaaccgca gctgatttat cacttagatt
    16141 tgttcctgct ttcaacattt caagtccata agtgtttaga tcgacttcag cgattgctgc
    16201 aagttctttt gcagctgctt catcttcagg cgtacatgtt ggtgatttga acaacaatgt
    16261 atctgaaatg atagctgaga gcatgattcc tgcgatttct ttaggaattg ttacttggtt
    16321 ttctttatat agttttaaaa taatcgtact tgtacatcca actggttctg cacgatagta
    16381 caatggatta gctgtttcaa agtttgcaat acgatggtgg tctactacag ctaaaatatt
    16441 tacttcgctg atatctgaaa tactttgttg gaattcatta tgatccacaa gcatgacatc
    16501 tgcattttct gctttagctg actctactac tcgtggtgca gatagctgaa agtggtctaa
    16561 tgcgtattgt gtttcttcat taggtgtacc tagagcaact gcttctgttt ctttacctaa
    16621 ttcattttgc aagtgtgaaa acgcaatggc tgccccgatt gcatctgtat ctggattttg
    16681 gtgaccaaaa actaaaattt ttgacatgtc attcgctcct ttgtgatttc tcctatttaa
    16741 taatagcaaa aaaacggaaa gaagcaatac ttatcttctt tccgatgcga cctatcgcgt
    16801 taaatatttt gtatactctt ctgtatgaag caatcgttta gcattttcga cacgttcttt
    16861 tgtaggtggt tcgatccctt ctaatggata tttcaaacca agtgtttccc acttgtattt
    16921 tcccatcgta tgataaggaa gaatctctac tctgtctaca tttgacaagg tttgaataaa
    16981 gttgtctagt cggatcaaat attcatcata atcacttcgc tcaggaacta gtacatggcg
    17041 aatccaaacc ggtttgttga tttttgacaa atattgagcc atttctaaaa tattttcatt
    17101 gtcccaatgc gttagttttt tatgctcttc attatcgatg tgtttgatgt caaataacag
    17161 taaatctgta tacttcatca attcttgaaa acgtgaaaag aaaggttctt catacgtaaa
    17221 aggttttccg catgtatcca atgtagtatg catcttccgc tcttttgctt ttttaaatag
    17281 ttcgatcaaa aaatcgatct gcaatagagg ttctccacca ctaacagtaa taccaccttt
    17341 atctccccag taaggtctga agcgttctgc tttatctaaa agttcatctg ctgtgtattc
    17401 tttccctccg ccaatattcc aagtatctgg attgtgacaa aattggcaac gcatgcggca
    17461 tccttgcata aacacgacaa agcgcagtcc aggtccgtct actgaaccga aagtttcgat
    17521 agaatgaaca tagccgattg ttttttcttc catttaagtt cacatctttt ctttgatttc
    17581 attttaagta caagttagct gtcgaagcga agctttctga acaaaatttt tcgcaattgc
    17641 cgcttcgtta tgtgtaaaat ttacagggac ggaacataca agtcctgccc ctgtaaatcg
    17701 tttctttcaa ataagcatac tgattattcg attttgatgc gatggctatt caacgtcctt
    17761 tcgacgctaa gtcgaaaaac ttttttcacg aactttttac attctgtcgt gtgaagttct
    17821 catcaagaca tctaattgtt gttctcttgt caagtcacgg aatttaactg cataaccaga
    17881 tacccggatc gtcaagttcg gatatttcat tggattttcc attgcatcac gcaataaatc
    17941 attactgaat acattgacat tcaaatgata agctcctttt gagaagtatc catctaagac
    18001 attacgcaag ttttcgattc ttgtatcttg ttcttttcca agacctgaag gattgattgt
    18061 ttgggtattt gaaattccat ccaatgcaca gccgtaattc attttagctg ttgagttcag
    18121 gctagctaat aacccacttt gttccgcatt gtaacttgga tttgctcctg gcgcaagtgg
    18181 ttttccagct tcacggccat caggagtatt tcctgtattt ttaccgtaaa caacatttga
    18241 agtaatcgtc aataatgaag ttgttggttt tgagttgcgg taagttttat gacgtttgat
    18301 ttgtcccatg aagtattcca agatccatga aactaattca tctgcacggt catcatcatt
    18361 tccgtattta gggaagtcgc catccacttc aaaatcaact gctattcctt tttcattacg
    18421 gattgctttt acttttgcat atttgatcgc tgacaagctg tctgccgcat gagagatccc
    18481 agcaatacct gtagcaaatg tgcgttgcaa gtcagaatcc atcaaagcca gctgagctgc
    18541 ttcataagaa tatttatcat gcatataatg aatgatgttc aacgtattga catatagttc
    18601 tgctaaccaa tccatcatat tcatgaagtt atgtttcact tcttcaaagt ctagtatttc
    18661 tgatgtgatt ggacgatatt ctggtccaac ttgggcgcca gtcacttcat cgactccgcc
    18721 attgatggca tataatagtg ttttagccaa gttagcacga gcgccaaaga attgcatgtc
    18781 ttttccgaca actgttcctg atacacagca agcaatcgca caatcatcag aaccccattg
    18841 ttcacgaagc tgattatcat tttcgaattg aatcgaagaa ctttcgatag cgattctgct
    18901 agcatatgtt ctgaatcctt ctggaaggtg ttcagaatac aaaacagtca agtttggttc
    18961 tggtgaaggt cccatatttg ttaatgtatg aagcagacgg aaatcattct ttgtaactaa
    19021 tgaacgacca tctaatccca tacctgcaat ggataaagta gcccagatag ggaatcctga
    19081 gaataattgg ttatattcag gtgtacgcgc gaatttgacc atacgtaatt tcattactaa
    19141 gtggtcgatc aattcttgtg cttctttttc tgtgattact ccattatcca aatcacgttg
    19201 gatatagata tcaaggaatg ctgagatacg tccgattgac atcgcagcac cattttgtga
    19261 tttgattgct gctaaatatc cgaagtatag ccattggaca gcttcttttg catttgcagc
    19321 tggtttagaa atatcatagc catatttcgc agccatttct ttcatttgcg ctaatgcacg
    19381 atattgttca gtgatttctt cacgtaaacg aatcacttct tcactcattg tatgataacc
    19441 agtcatatca tgatcttttt tcttttgttc catcaaatag tcgattccat acaatgccac
    19501 acgacgatag tcaccgatga tacgtccgcg accgtaagcg tctggaagcc ctgtaatgat
    19561 tttgttttta cgagcagcac gcatttcagc agtataagcg tcaaatacac cttgattatg
    19621 tgttttgcgc cagtcagtga aaatatgtgt caattcatcg tttggtgtat agccattgct
    19681 ttttagcgca ttgttagcca tattgattcc gccgaacggc atgaatgctt gtttcaaagg
    19741 tttgtctgtc tgtagaccga cgattttttc caaatcttta tccaaatagc ctgcatcgtg
    19801 tgaagtaata gttgatacga tttctgtgtc catatcatag acaccgttac gctcgaattg
    19861 gatatcattt aacttttgca attcatccca taatttttct gttgcttctg ttgggccttc
    19921 caaaaagctg tcatcaccgc gatattcagt gtagttattt tgaataaagt ctctagtgtc
    19981 tacgccttct ttccatttgg tacctttaaa tccattccat tgctccattg tatggacctc
    20041 ctaaatttct gttttatgta acagttttta cgtgattagt ataacacagc accctatctt
    20101 tgcaagggtt ttcttgtttt ttatttaaca atttttatgt tttatttaca tatatttaaa
    20161 tcaacgttga cataccaaca tttaagcatt gtgaacactt tcatcttttt ttgcaaacgt
    20221 ataaggattt attaaaaatg aatgaaaaag agacgccacc tgtattaata cagatggcgt
    20281 ctcttcatta aaatactaca acagttacga ctcgatgaaa atctcaggag catcgataac
    20341 ttcgatgact tctccacctt ttttctcatc catcgcaaat gatccattcg atgttcgatc
    20401 acctataggg aaatcagttg ggtcaatcgt taactgctgc cctttttgat tcatcaaggt
    20461 tatttctttt gatcttcctt ccgacatata gataatacgg tgcggatttt ttttcagctc
    20521 acgcatgacc gtcactcccc gcttcgcacg tgaagtttgg ctgatttctt gagcaagcat
    20581 gcgtttaaca gctcctcgct gagtaacgat tacgatcggc gtatcacctt ctgctaacac
    20641 aagcagcccg ttgataatcc tatctccatc tttcaaattc atagacttca ctccagctgc
    20701 ctttgctcca acaacgggaa catctgttaa aggatagcgc aaacccattc cttgatgcgt
    20761 tactaagaaa acatctaagc ctggctgatc ttctttcaga tacacagcaa tcagttcatc
    20821 ttcttccgcc tttagcttca tacagctgag cggacggctc ttataggtgc gccatggttc
    20881 gaactctgtc attcgtgttt gcttgatcaa tccattcttg ctgatgaata caaatgtttt
    20941 ctctgcttga attttttgat atgggaaaac agctaaaatc gattcgtcta cagacagatt
    21001 ggagattgtt tgagaaatgt gctcaccagc atctttccat ttcaaatcgg gtagttcatg
    21061 gacagggcgg tagatcacat ttgctttatt tgtgatcaga agaacatggt ccaatgtact
    21121 caattcacct gagtatagca agtagtcgcc ttctcgcatc ccgatttctt ctggtttgga
    21181 agcactataa gaacgaaggc ttgttcgctt cacatagcct tctcgcgtca cactgacaat
    21241 tacgtcttct tgtgccacta agacttgcgt atcaattttg atttcttcga tttcgtcttc
    21301 gattgtcgtt agacgagcgg aagaataatt ttttttcact tctcgcaatt cttttttcat
    21361 aacagagaaa agctctttgt catttgaaag gattttattc aactctgtga tttgcgcaat
    21421 caagctttcg gattcctttt gaagctctgt gatatccgtg ttcgtcaaac ggtataattg
    21481 caatgtgaca attgcttctg cttgttcttc tgtaaattga aagacgtcga ctaaattctt
    21541 tttggcgtct tttttgtctt tactttcacg aatcgttgcg attacttcat ccagaatcga
    21601 taaagctttc atcaatcctt ctacgatatg ctgtcttttt tgagctttgg ctaaatcgaa
    21661 ttgactacgt tttgttatga cttgctttcg atgctcgata taacttctta aaatgtcttt
    21721 cagtccaact tgatgcggag tcatatggtc gatagcgacc atattgaaat tgtaattgat
    21781 ctgtagctca gtgtttttga acaaataatt caaaattcct tgagcattgg cgtctttttt
    21841 caattcgacg acaatttgca gacctgttct atcactttca tctcgtactt cagctattcc
    21901 atcgattttc ttattcaaac ggatctcatc catttttttc accaaggtcg ctttatttac
    21961 ttcatatggg atttctgtga tcacgatttg ctgtttatta cccttcattg cctctatctt
    22021 tgttttcgaa cgaagaataa cttttcctcg tcctgtttca taagcttttt tgatttcatc
    22081 ttttccttgc aagatccctc ctgttggaaa gtcaggtcca ggaatatatt ccatcaattt
    22141 ttcaaggctc gcttgtggat gatcgatcat atagattgtg ccatcgatca cttcagctaa
    22201 gttatgagtc gggatttctg ttgcatatcc agcagatata cctgtcgatc cattgacgag
    22261 aaggtttggg tatcgagctg gaaggactgt tggttctttt tctgtatcat caaaattcca
    22321 cacgagatcg actgtttctt tctcgatatc tgctagcatc tctccactta acttggataa
    22381 tctggcttca gtataacgca tcgcagcagg tggatcaccg tccatactcc cgttattccc
    22441 gtgcatttcg atcagtactt cccgcaactt ccagtcttgg ctcatgcgga ccatcgcttc
    22501 ataaatactg atgtcaccat gaggatgata attccccatg atatttccga cagattttgc
    22561 tgatttacgg aatcctttgt catacgtatt gccatctttg ttcatggcaa ataatatccg
    22621 gcgttgcact ggcttcaatc catcacggat atcaggcagt gcacgttctt ggataatata
    22681 tttggaataa cgtccgaagc ggtcacccat cacttcttct aaagttaatt cttgtacttc
    22741 ttgtcgattt tccatcaggt gacctcctat tctacttcaa ataactgatt gttttcattt
    22801 ttatctgctc gttcttcatc taataaatca ttagaaactg aaggagagat ttcagtatcc
    22861 tcttttttat ctaagatact gccatcttct tcgagcgtaa attgcacgtg attttcgatc
    22921 cattttcttc gaggttctac tttgtcaccc atcagtgtgg ttactcgacg ttcagcttgc
    22981 gcagcatcat cgatacggac gcggatcaac gtacgggaag tcggatccat cgttgtttcc
    23041 cacaattgtt ccgcattcat ctctccaagt cctttatatc gctgcagcat atatcctttg
    23101 ccgacttttt taatcattgc tgccaattcg tcatctgtcc acgcatattc aatgacttgc
    23161 ttctttcctt gtcctttgga tactttatat aaaggcggta acgcgatata tactttccca
    23221 gcttcaatca gcggtttcat ataacgataa aagaaagtaa gcagtaatac ttgaatatgg
    23281 gcgccgtctg tatccgcatc ggtcatgatg attactttgt cgtaattaca gtcttcgata
    23341 gaaaactcag gaccgactcc tgcaccaatc gtatagatca tcgtattgat ttcttcattt
    23401 ttcaagatat cttgcatttt agctttttcg gtattgatga cttttcctcg taaaggtaga
    23461 attgcttgga actttctgtc tcttccttgt ttagcagatc cgccagcaga atccccttcg
    23521 actaaataca attcattttt cttagggttt cgggattgtg cgggtgtcaa ttttcctgaa
    23581 agaagagatt cgcctttttt acgcttcttc ccatttcggc tttcttctct ggctttacgt
    23641 gctgcttctc tcgcttctct ggctttgatt gctttacgga ccaacatctg gctcatttcg
    23701 ctattttcct gcaaataaaa gcccatttgt tcactgatga cgttatctac tacggtacga
    23761 gcaactggcg taccaagttt ttcttttgtt tgcccttcaa attgcagaag attttcaggt
    23821 acacggatag aaagtacagc agctaaccct tctctgaaat cactaccttc cagattcttg
    23881 tcccgttctt tcagcaaacc aacttttctc gcatattcat tataagattt cgtcatcgcc
    23941 gctttcatac cagcttcatg ggttccccca tcttttgtcc gaacgttatt gacaaaagat
    24001 aaaacatttt ctgaataacc gtcattgtat tgataagcga cctctacttc gataccttct
    24061 ttttctcctg aaaaataaac aactggtgtc aatgtatctt tttcttcatt cagataatca
    24121 acaaattctt tgattccttc ttcgtaatga aaaatttcct tgactggttc ttctccacga
    24181 agatcagaaa gagagatttt aacgcctttt agaagaaagg cagattctct taaccgttcg
    24241 gctaaaattt catatgaaaa tttcgttgta ctgaatattg tatcatctgg taaaaaatgg
    24301 acagtcgtcc cgtttgcttt ttttgttttt cctatctttt tcaaagtacc gtcaggttta
    24361 ccgccgtttt taaatttctg ctgatactct acgccatctc taacgatcgt tacaattagc
    24421 catttcgata aggcatttac cacactggct cctacaccgt gcagtccacc agaagttttg
    24481 taccctcctt gaccaaactt tccgccagca tgcagcacag taaaaatcac ttcaactgtt
    24541 ggtattccgg aagcatgcat tcctacaggc atcccacgtc cgctatctgc aacagttata
    24601 ctattgtctt catggatggt cacatcaatc tcactgccat aacctgataa tgcttcgtca
    24661 actgcattat cgacgatttc atagactaaa tgatgcaagc ctcggctgtc agtggatcca
    24721 atgtacatcc ctggtctttt tctaactgcc tctaatcctt ccaatacttg gatggacgag
    24781 tcattgtatt cgttgtttac tttttttgcc aaggcaaacg ctccttcaat aatactttgc
    24841 ggcaaaaccg caccacgatt atcatactag aaaaggtcgt gaaaaaaaag agggtagacg
    24901 agaaatcaat tttaattatc tcctaaccgc tttttcgaca ttcccctcta tcgatcatct
    24961 cttctttgtg gtcattttta tttttggttt tctttcaact taccaagttc aatcttaata
    25021 caacgatcca ttacgatatc tgtacgtcct gcttttctta gcatctcagc tgcttctttg
    25081 ttttcaatcc ctaattgtgc ccagaacact ttagcatcag ttttcaaaaa atcacctgct
    25141 atttcaggta aaaattcact ccgtctaaat acatctacga tatcgattgg atcatcgatt
    25201 tctgtcaaat tcgcatagac tttctcgcct agaatttctt caccagccaa taatggattt
    25261 actggtatga ttttatatcc attgtcttgc aatacctgtg caaccatgta acttgttcgt
    25321 tctggtttat tgctcaagcc tacgacggca atattttttg cttcttccaa atagttgaaa
    25381 atcgtttctt gtgttggatt ttttacagac atttctgcca ccccttgctt ttctttttat
    25441 tccatctatt atacttgtat ctttcatttt ttcaattgtt cctgttacct attcatgcta
    25501 aaataaagga tagttttcaa cttgaaagag ggtaaaaaat gaaattgatc ttattactta
    25561 ttttagcata tcttttaggt tctattcctt ccggtgtctg gattggcaaa ttgtttttca
    25621 aaaaagatat ccgacaacac gggagcggta atactggaac gaccaataca tttcgtgtat
    25681 taggcaaaac agccgggatt gttgtcctgc ttatggatat tttaaaaggt acattggcta
    25741 cttgtttgcc gatgatcttc cacctttctg ggattaaccc tctttggttt ggggtatgcg
    25801 ccattcttgg ccatacattt ccgatttttg ctgggttcaa aggaggaaaa gctgttgcga
    25861 caagtgcagg aatgctttta ggatttaatc ctgtattttt tgtttattct tgtatcatct
    25921 ttatcgttag tttattttgt acaagtatgg tgagtttgag cagtatgatc agtgcagtat
    25981 tgatcacttt atctacgatc gtccttcctt atgtagctcc tgtgattttg gctaagccca
    26041 attggttact gacgatcatt gcctttttag tttcttcctt tatcttttat cggcataaag
    26101 acaatatcaa gcgtatcaga aaccatactg aaagtcgaat cccgtttggt ttgaatagca
    26161 gcaagaaaaa atcctgatac tttttcattc caaagagata aaacgggagt gtgacaaatc
    26221 gatgtcacac tcccttatta cttacaggat agctttttta cacaccttgg taaacggtgt
    26281 tccctgctaa cttctcggtc acaacctctt acttcactgt gatggaatat tttgtcttga
    26341 agatttcatg ggcacctagt tgattgatcc ctactttttc catcaagttt ccactactgt
    26401 tcaccgtgtc agcgattccg caccacggtt cgatacaaac gaaaggcgct tcttttggat
    26461 aaggagacca gatccctaca taaggcatat ctttatagct taaagttacg ctatgggaag
    26521 atttttcact tcgaatggcg tacgcattta gaccccttgt ttcaaaaacc aaggcatctt
    26581 gctcaaaaag ttcacgattc aaagccagat tcgtatttgt ctgacctaac gtcttttgat
    26641 ccatatcgat gaatgggcct ttcaatggta ggcgtaatct tgatttcaat ggagaaaatg
    26701 ccagatagaa atcttcaaat gacaatcctt cttcaagagg tacattgaaa gcaggatgtc
    26761 caccgataga aaagaacatt tctttttcac cggtatttgc cacttgataa tgaaccgtga
    26821 tgccgtctcc tcctaattca tagctgatca ctaattcaaa atcaaatgga tacttttcta
    26881 atgtctccgg cgtactcctt aagatgaaac tagccatttc ttgtccatgt tcaatgactt
    26941 caaaatccat atcccgagca aatccgtgtt gccccatttg atatgttttc ccttgataaa
    27001 catactgatc atcttttaaa cgtccaacaa aagggaataa aaccggtgca tgtctgcccc
    27061 aatacgctgg atcaccttgc cagatatact ctaaaccatg ttcttttgat ttcagactga
    27121 tcaattccgc accgtgttca gcgatttcgg cgatcagctg gtcattttga ataataacag
    27181 tcattgccat tcctccaact tcgacttact ttttaaaatg ggaaggctgg aacaaacatt
    27241 tctatctgcc ccagtcccct tacttctaat aactgtgttt tgctaactcg tctttaaaac
    27301 gggaattcaa tacttttaaa taagttccct tcatgcctaa cgaacgagat tcaatgattc
    27361 cagctgattc caattttcgt aaagcattga cgatcacaga acgagtgatg ccgatactat
    27421 cggcaatatt agaagcagtc agacgacctt catctccatc caatgcttca aagatagctt
    27481 gtacagcctt caattcgcta taagataatg tgttgattgc catttggaca gccgttgcac
    27541 tccgtacatc tgcttcgatg cttcgagact tctgataaag gatctgcata ccgacaaccg
    27601 tagctccata ttctgctaag actagatcgt catctgcaaa cgattgttcc atacgagata
    27661 agataatcgt acccaaacgt tcgccagctc caaagatcgg aacgacagtc gtcagaccaa
    27721 atggatattt ctctcttgac tctaccggaa atgcagtaat atcactagta attgggatat
    27781 tagcttcagt tttcatcaac tgtgccactg tatcagtata agattcagga aattgtttct
    27841 caacaaacat tgttttgatt cgttcattgt tcacatcgtg acgttcatta taacctagta
    27901 atactccgtc acttcctatg atataggtgt tgctgtcaag aataccacct agtgtgacag
    27961 ccattttatc gtaaggcaaa tctgcttgca tgtcaaaagt attcttttgc tgcaaaagtg
    28021 tgtttatctt gcgggttttc gttagcaagt ctgtcattgt cgtcctccga ttttttataa
    28081 aatatagcga cttaaatctt catttgccgc aattgagcca agtttgtcat ccacatatgc
    28141 ttctgtgatc gttatttctc ccatttgcat atctggtgct tcaaataata gatcttctag
    28201 tagtttttcc aaaatggtat gcagtctgcg tgcgccgata ttatctgtgt cacggttgac
    28261 atcgaaagcg atttgagcga tccgttcaat tgcttctttt gtaaacgtaa ctgacacatt
    28321 ttctgtaccg atcaacgcga cgtattgttt tactaaagca ttatttggtt cggtcagaat
    28381 cttcacaaaa tcttcagctg tcaaatcatc taattctacc cgtatcggga agcgtccttg
    28441 aagttctgga attagatcac ttggtttaga caaatggaaa gctcctgaag caatgaatag
    28501 gacgtgatct gtttggatga tcccgtattt tgtgtttact tgtgaacctt cgacaattgg
    28561 caatatgtct ctttggacgc cttctctgga tacttctcca gattgctgtg atttagaagt
    28621 gatcttatcg atttcatcga taaaaataat tccactttct tccgctaatt tgattgcctc
    28681 actatggata tcagcatcct tgactaattt tgctgattct tccttgatca ataactctaa
    28741 agcttctttg actgttaccg tccgttccac ttttttcttc ggtgtcaaag cacctagagt
    28801 ttcatttagg tcgatcccca tttgctccaa tccattgttc atcattggtg caggtttctt
    28861 ttggtcttca acttcaatgg ttacttcacg actatccagt aaaccctttt gtagttgttc
    28921 caagactgta cggcgattga ttcgaatatc ttctgtcact tcttcttgcg gttcagcggt
    28981 attttgctga ctagcattaa aaagattcat catttgttca aattgattag tggattgttt
    29041 ctgttctttt ttgataccag gtaccaagat ttttaccaaa cgtttttctg catttttttt
    29101 agcacttgtg tatacacggc tgtactgctc tttttctacg atttggatcg cattttctac
    29161 taaatcccga accattgatt ctacatctct tccgacataa ccgacttcag taaattttgt
    29221 tgcttcgact ttgacaaatg gtgcattgac gatttttgcc aaacgtcgtg cgatttctgt
    29281 tttaccgacc cctgtaggtc cgatcatcag catatttttt ggtgtaatat cttgttgcat
    29341 tttttcatct aactgcaaac ggcgatagcg gttacgcaaa gcaacggcaa cagatttttt
    29401 tgctgcgtgc tgtcctacga tatattcatc taattcactt acgatttgtc ttggtgtttg
    29461 ttttaattca tacatatcta ctcacctctt acagttcttc tacgataata ttatgattag
    29521 taaagataca gatatctgcg gcaatattta acgcattttc tgcaatttct ttcgcactca
    29581 tgtcgttttg agcatagttt ttcattgctc gggctgcagc caacgcaaaa ttccctcctg
    29641 atccgatagc taagatacca tcatctggtg tgataacttc tcctgtacct gaaacaagaa
    29701 gcatttcttt atcattcatt acgatcagca tcgcttcaag tttttgcata gattgctgtg
    29761 tccgccattc ttgagctaat tcgacagctg cgcgttgtag attcccgtta tattcgttta
    29821 gtttgccttc aaatttttct tctaaagtaa acgcatctgc aacacttccg gcgaaaccta
    29881 caacaacttc tccattgtag atacgtcgta ctttctttgc agtgcctttc atgacaacag
    29941 attcacccat tgttacttgg ccatctccag ccatagcaaa tttcccgtct ttttcgacgg
    30001 cacagatagt ggttgaatga aatggtgatt cgaccatgtt tgtttcctcc taaatttgtt
    30061 cttttcctta tttttacgct cttggatgga aagaacgata gtttttttgt aaactttctt
    30121 ttgttacatg ggcatagatc tgggtagtcg ataaattggc atgtcctagc aattcttgga
    30181 ctgtccgcaa atctgcccca ttatttaata aatgagtagc aaatgtatgg cgcagcatgt
    30241 gaggatggat atcactatcc aaactgcttt ttttgatcat ttgattcaag acatattcaa
    30301 ttccagtagg cgtgattggt tttccatgat gattcacaaa aacgatatca tgctcttcgt
    30361 gatattttgt catcaatacc tggcggcctt ccctgaaata ttcttgcaga gcatcttgag
    30421 caaaagaacc tagaggagca tatctctctt tgttcccttt accatggatc aacatgacct
    30481 ctgaatcaaa atcaatgtct gataccgaca aactgctaca ctcacttaaa cggatgcctg
    30541 acccgtaaag gacttccagt aaagcgcggt tcctcaaatc caaaggacta tctcctgcta
    30601 cgctgtcaaa aagtgcttgc atttcatttt cataaaaaaa acgtggcagt ctcaaatttt
    30661 tctttttgag atgaacgtaa gaaaatggat tttcttttat cacttcttct ttgagaagat
    30721 actgataaaa cgaacgtagg ctggctatct tgcgactgat agaatttctg ctatagctag
    30781 gacgatgatc agctaatgca ctcaaataga cacgaaccgt aaaatattcc gccttcagca
    30841 gatcagcgtc tccagattcc tccaaaaaat gtttgaaatg gagaatgtct tcttcatatg
    30901 cttctttcgt tttttctgaa tatcctcttt cgacaatcaa ataacgcaaa aatttttgtt
    30961 cccacgtggc ttctgtcatt ttctcacctt ccttttgtcc cagagaataa tttagcacag
    31021 cgtttataaa aagacaaata aattgtcaga atttaaccaa tatttctaag tttgttcaca
    31081 attggcgcaa ttcctcacat tttgtttgag aaattcttaa gaaaaacgca agaaaaagag
    31141 cgagactatc cgtctcaccc tcttcatgga gtttccttac tcatttggga ttgcagtttt
    31201 ttctaattct gtttttattg cctcattagc ttttaaagct cgttgtgcaa ttgcttcata
    31261 tcttgctttt ttgtctcgaa tgcgctctgg cagttcagga aacagaccat agttggcatt
    31321 catcggttgg aaatgttttc cttccgcatg agtaatgtag taagccatac ttccaatagc
    31381 tgtttcttgt ggaaactcga ctggttccat ttcttttgct aagcgtgcgg cgttgattcc
    31441 agcaagtagt ccgctcgctg cactttcaac atagccttct acaccagtca tctgacctgc
    31501 aaagaacaga tcttcgcgtt tcgttgattg gtaagtcggt ttcagcaatt ctggcgaatt
    31561 cataaagctg tttcggtgca tcacaccata gcgaacgaat tcagcatttt ctaacccagg
    31621 aatcatccgg aaaacacgtt tttgctcgcc ccatttcaag tgagtctgaa agcccacgat
    31681 gttgtataaa gaagctgcag cattgtcttg acgcagctgg ataacagcat aaggacgttt
    31741 gccagtttta ggatcttcca atccaactgg tttcataggt ccgaaaagca tcgttttgaa
    31801 tcctcgctgt gccattactt caattggcat acatccttca aaatattttt ctttctcaaa
    31861 agatttaagt tctgccactt cggcattgat tagtgcctca tggaaagctt tgaattcctc
    31921 ttctgtcatc ggacagttca agtaagctgc ttctcctttg tcatagcggg acttcaaata
    31981 tactttatcc atatcgatcg tagctttgtc tacgattggt gcagctgcat catagaaata
    32041 aaaaccatct gaaccattga atgctttgat gctttctgct aatggatgag aagtcaaagg
    32101 tcctgttgct actacggtga ttccttccgg tatttcagta atttcttcgt ttatcactgt
    32161 tactaatgga tgctctttga cttttcgggt aattgtttca gaaaaagaat cgcggtcaac
    32221 agctaaggca ccaccagctg gcactgctgt ttcatctgcc gaagtgatta ctaccgaatt
    32281 caatcggcgc atttcttctt tcaataaccc tactgcatta gccaaactgt ttcctcttaa
    32341 tgaattggaa catactagtt cagcaaaatt acttgtgtga tgcgcctcag tcgatttgac
    32401 tggacgcatt tcatataaac ggacagggac tcctgcttgt gcgatctgcc aagcagcttc
    32461 acttccggca agccctgctc caacaacatt taccattttc aatgaaagaa cctcttttct
    32521 attatttttg gatgtcttct tcgtaatctc catttacaca gactacttgt ttaccgcctt
    32581 tgactttctt ctcgaccaga tatccgtcac attttggaca atttctgccc actggtttat
    32641 cccaagaagt gaattcacat tctgggaaac gggaacaacc atagaatagt ctgtttttct
    32701 tagattttcg ttcaatgact tgtccttcat gacatactgg gcaagtcaca ccgatttctt
    32761 ttacgattgg tttcgtattc cgacaatcag gaaaattact gcaagcataa aacttcccat
    32821 atttccctaa ttttatcacc atcggatgtc cacagacatc acaatcgaat cctgctggtt
    32881 catctttgat ttgaattttt tcgatttttt cttccgcatt cgtcagttct ttttcaaacg
    32941 gtttatagaa acgatcaacc actttgaccc acgcttccgt gccttcttca attttatcca
    33001 aatctccttc catttctgct gtgaaatgga tatcgacgat ttgagggaag aattcacaga
    33061 ttaatgaatt gacaatttct cctagttcag tcggctcaaa tcttttttgt gtcaatttta
    33121 catagtagcg tctttggatc gtatcaagtg ttggtgcata agtggaaggt cgccctaccc
    33181 cgttttcttc tagtgcacga atcaacgtag cctcactaaa acgtgctggt ggttgagtaa
    33241 aatgttgttt tggttcaata tcaacagatt ggactacatc gccttcttca agttctggaa
    33301 gaatattttc tttctcttct ttgccgtcat ctctaccttc cacatacact tgcatgaatc
    33361 ctttgaattt gatttttgaa ccgttcgcaa tgaagatgac accattttgt tctaatgtca
    33421 ctttcattgt atctaaaata gctggtgtca tctgactagc cacaaaacgt gaccagatca
    33481 atgtataaag tttcaattga tctttatcta aatattgttt gagttcatct ggtgtacgaa
    33541 gcacactcgt tggacgcaca gcttcatggg catcttgtgc gccttgagca tttttgatct
    33601 ttcggtgatc atgtctagaa aattcttttc catacgtatc ttcaataaat gctgcggcct
    33661 ctgcttttgc tgtatcggca atccgggtag aatcagtacg catgtatgta atcaagccga
    33721 ctgttccttg tttacccaaa gtgattcctt catataattg ctgtgctacc atcatggttt
    33781 ttcttgttcg aaagtttaac ttacgggcag cttcttgttg caggctactt gtagtgaaag
    33841 gattcgcagg gtttcttttg cgctctttct tttctacttt tttaacttcg aagtctgttc
    33901 catcaattct agcagtgact tcttttacac tttgtgcatc tggtaatttc tttttcttac
    33961 cgtcgattcc ccagaaattt gctttgaatt tcttgcgagc ttttttaaaa ttaccgtcga
    34021 tgctccaata ttcttctgga acaaattctc ggatctcttt ttcacggtca ataataattt
    34081 ttaaagcgac agattggaca cgtcctgcac ttaacccttt cttgacctta cgccagagaa
    34141 taggactgat cgaataacca acgattctgt ctaaggtacg acgagcttgc tgtgcatcta
    34201 ctaaatctac atcgatcgtt cttggttcct taaaagctgc tttgactgcg tcttttgtga
    34261 tttcattgaa gaccacccga tttttttctt tcagatccaa cccaagtagg tacgctaaat
    34321 gccaagcaat cgcttctcct tctctatccg ggtcacttgc caagtaaact ttttgagctt
    34381 tttttgctgc ggctttcagg cttttgatga catcgccttt tccgcgtata gaaatataat
    34441 ggggttcata attgttttca aaatcgatac ccattttact tttcggtaaa tctcttatat
    34501 ggccaacact ggccattact ttatagtttc gtccaagata tttctcaatt gtcttggctt
    34561 ttgcaggtga ttctacaatc actaaatatt tatacgccat tactgaatgg actcctttcc
    34621 attgtcgtgt tcctactatt aaaagaggat tcatacaaat cgtagctaat catatccatt
    34681 cagaaaacgt ttgtcaagaa aagcaaatga aaagtatggt gttattcttt aaattctgcc
    34741 aagatatctt cacccgaaac cgtgcaaact gcaccgtctt ggatcaaatg atgacatccg
    34801 gtagaatgtt ctgttaaaat atttcctgga acagaaaaaa ctgttcttcc aagatccaat
    34861 gcttgctgtg ctgttatcag agagccgctt tttttcttgg cttcaaagac acatgttcct
    34921 ttagacaaag ctgcgataat ccgatttctc attggaaaac aatgcttttt cgggccggat
    34981 tgaggaggat attcactcaa aagaagatga tcatttgcaa tcacctcttg caagtcacga
    35041 ttttcagcag gatagacttg ctctatccct gttccaatga ctgcgattgt ccgtccacca
    35101 tgagagattg ctgcttggtg accgtatgta tctatccctt tcgcgcagcc actgacgatc
    35161 acatatccag cttctatcac tggttttagt aaataataaa ctgttttttt ggctaaagca
    35221 gaagtgtgtc ttccaccaac aacgcttaac atgttacaag aaagtaaaga tagatcacca
    35281 ttataaaaca gtacaattgg cggataggtc aagtgaagca gctgaggggg atatttggga
    35341 tcaaagcaag tgataaacga ctgtttcgat tggattttgc cccagttagc gtgaatttcc
    35401 tgccaacttt tgcgaaacag ctcccggtgt ttggttattt tacctatctt aatgatgtct
    35461 tcaaatccga tttctttata aggatactgc atcatccagt tagcaagtgc ccattttcct
    35521 tgactactga ttccttttgt ataagcaagt ttcaataaat tttcttctat ttgatacatc
    35581 ataaaaccgc ctttcgtctc tctttctaat aagatacgta aaagcggctg ttttttattg
    35641 taaatatttt tttacaggtg caaaactttt acgatggatt ggcgtaattc cttgtcgttc
    35701 aagtccttct aagtgttcct ttgttccata acctgcatta tgcgagaaac catatccagg
    35761 ataaagcacg tcatattctt tcatcaattg gtctcgatat actttagcaa tgatacttgc
    35821 agcagcaatc gacacagatc gtgcatcccc tttgattatt ttttcctgct gaataggcaa
    35881 atccaaggtc atcgcatcga tcaacaaata gcttggtaca atggacaatt tttctactgc
    35941 ttggatcatc gctaatttac ttgcttcata aatattcaca tcatcgattg tctgctgatc
    36001 aacgatcccg atcccgattg ccagggcttt ttcttgaact tgttgataaa gaagttctcg
    36061 ctttttctct gataattgtt tggagtcatt cagccctaat atgatctcat ttttcggcaa
    36121 gataactgca gctgccacga caggtccagc taatggtcct cttcctactt catcaatgcc
    36181 ggcaatccat tggtgacctt gtgcgtaccc ttgcttttca aagcaaaaca tttcttcata
    36241 tttttcctta attaatgctt cctttttcaa tcgtcgttca aaagaagcca gtgcttgctg
    36301 cacgcctttg cgtggatcat ttcttaatga ttctagtgta ggatcatcta ttctctgtat
    36361 gcttttcaat cgttctttga tactttggat ggattcagtc atcacttttt tgctccattt
    36421 cttcgcaacg atccagtgtg tatcgtccaa gttttccttg acgaatatca tgcacgacta
    36481 attcgctgcc acgatcatag tcttctttat acccacgttt tgctgtaata tccatcagta
    36541 attccggtgc caatttttct tcttgctcga ttgataaacc ataacgatcg ctgattcttc
    36601 ctgaataata tcgggcaaaa aagtctaatc cgtaaatcgc taaatcatct aaatggacaa
    36661 gctggtcttt gatcgcgcct gtcagcgcta gttttttgcc gatttcttca tcttcaaatt
    36721 tgggccataa aatccctggt gtgtctaaca attccaactc attacctaaa cgaagccact
    36781 gctgaccttt tgttacgcca ggcttatttc ctgtctgtgc aattttcttg cctactagtc
    36841 gattcatcaa cgtagatttc ccaacatttg gaatacctaa gaccattgcc cgaatagcgc
    36901 gaggcttgat cccccgagca gcatctcttg cccgtttttc tttcaatgct tctttagccg
    36961 caggtactag acctttaatt cctttacttt cttgtgccgt gatagctaat gcaagatggc
    37021 cttgtttacg aaaatattct tgccacagct ttgtctgttg tggatctgcc agatccgctt
    37081 tattcaataa aacaaggcga ggtttttgct gaatgatctg atctagcatt ggattacgag
    37141 aagataaagg taatcgtgcg tctaccaatt caaatacgat gtccacatat ttcatttttt
    37201 cagaaacttc tcgtcgggct tttgccatat gtcccggaaa ccattggatg gtcattgttc
    37261 tctccattcc tttcataccg gaatattccc cggctttact tgtttttttc tttttcaata
    37321 taaattcact tttttattat aaagaaattc catctattag ttaagtgaaa gtgaaccagt
    37381 cctcattcta tcacatcttc acttttttga tgatgcaaat ttttattttg gtttctatat
    37441 atgaatctaa atttttgaca gcgtttccta aataagagat gatagacgaa caaaacagaa
    37501 aggagacgaa acaaatgaat agtatggttt ttgttaattt tcctgttgct gatgtcaatc
    37561 gttccgttgc tttttatgaa aagctgggtt ttaaaaaaaa tgaagaattt tctactgaag
    37621 aagctggttc aatggtatgg gatgacactt tttggataat gcttctctct catgattttt
    37681 ataaaaaatt tataaaagat aaagaaatag ctgataataa aaaaacaagt ggtgctttga
    37741 tttcgtttag tgttgaaaat gcggatgaag taaaaaaatt tgctcaaatt gcaaaagaaa
    37801 atggtggtac tttccacgaa gtagatatgg gaatgcctga agaagaaatg ttttcattag
    37861 aagtccaaga tctagacgga aatacattag aacccgtatg gatgaagatg taagcagata
    37921 actaatctga cgttttttat aacaaaaaaa caaaggcgga tgatacgata agtattctcc
    37981 gcctctattt tttttattcg tacaatctct tttttacagt ttataaaagc agtcttctca
    38041 cccttttttt aattgttaga tgccagtgta tgtaaatcac caatgtgtca tgacacattg
    38101 gtgattttat ggtatccttt tattattaac tgacaaagga gagaatattt tgaacacttt
    38161 gattgcaaaa gacgttttta gattgcccga aatgaatgca agattgttgt cgacctctgc
    38221 tcttttatta gcccttgatg tcatcttata caagatagcg attggtcctg cttattttca
    38281 aatcacattc ggatttttaa gtatggcgct tatgggttat ctatatggac cgatctgggc
    38341 tggtttgctt gaaatgttgt cgaacacttt aaatttcacg atatttggtt caggaacgtt
    38401 tcaagctgct tttcttatca cggctttcct tggtggattt attaatggct tatttttata
    38461 tcataaaaag ataaacctgc cttccgtcat cgctgcccaa ttattgatta tgatcccagt
    38521 cagccttttt atcaattctt ggctgatgtc tgttttgttt ggtgcagatt tcaaagtaat
    38581 ttttctaggt agattcatca ggaatatgat ccaaatccct attcaaataa tggttgttta
    38641 ttcatttatc aaaactttag aggctagaaa agtgtttaaa cgagctgttt gattttacgt
    38701 actaaggtag taaactgatt ttggattaaa caataaagcg tgcagtctca acagactgca
    38761 cgctttattg tttctcactg gatccatttt atttcatcaa gtggataata gacaaatctt
    38821 gctttaccta gaatatcagt tttattgatc gtgccaaacg aacgactatc ttttgaaact
    38881 cttcgattat ctccaagtac aaaataatta tcttccggaa gcttggattg tcccgttagc
    38941 tcttgtagtg taaagtccgt cgtataggat gcatttgcat gatctgattt caggttttta
    39001 gttagataag gttccttaac tactttccca ttgatcttca attgatcatt ttggtagctg
    39061 acattttctc ctggaagacc gattactcgt ttgatataaa tcgtgccatc tgctaattga
    39121 aaaacaacaa tatcaaatcg tctgatctcc gaaaattttt ccatcacaac catatcacct
    39181 tgcttcaaca cgttttccat tgaattgcct tccactggta ccgggatgaa taaaaatccc
    39241 cgcaacatga acgcaaggaa tacagaaaca agtaagtatt tgaatacaag ccagaagcga
    39301 ttaatatagc gttgtttttt tgtcaatctc tatcaatcca tccctctttt tttcattctt
    39361 tctttattat aagaaaaata tcaaaaaaat gcgactagat agctgaaata aaaataattc
    39421 tttcaattag gctattggac aaaaaacttt tttgatcata aagtacaaaa ctatctctta
    39481 tatgtcatga ttattttcta aatatttttc ccatgcttcg tcaaagatat ccatggacgg
    39541 caaatagtcg acattcagtt ccagataatt agaaatttct tcgtagctag agctgtgctt
    39601 aggaaattgg atgtctttac cggcttctgt agcgaaaaca gataaagcat catgtgtgcc
    39661 accgcctcgc agtgtcatta aataatgaaa aaagcttcga ttcacccttc gttcctccaa
    39721 ttttcttcga taaaggcagc ccggcgtgca tggtttcttt taaaattttc aggatgcttt
    39781 ttataatact cttgatggtc ttcttctgct agataaaatg gttgggctgg ttcgattttt
    39841 gtaacgattg gctgttcgaa acgtccactt tcagctaact gtttcttact tttttcagca
    39901 atgatccgct gttcttctgt caaataaaag atcaccgggc gataattgtc accgcgatcc
    39961 tcgaattgtc cgaaagcgtc agttggatca gtttgctgcc agtaaagttc tactaattgt
    40021 tcatatgaaa tcaatgttgg atcatagata atctccactg cttctgtatg tccagtcgtt
    40081 tggcttttta cttgttcata agtcggatct ggtacatgcc ctccagtata tcctgacatc
    40141 actgtatgga taccaggaag cgtgtcgaaa ggctggatca tacaccagaa gcagcctcct
    40201 gcaaatattg ctcgttccat tatgattccc cctctaatac tactcatccg atgatttttt
    40261 attttctttt gtcttgcttt cagtactgct ggtgctagtt ttgttggtat ttgagttgtt
    40321 tgaagcatca gaggtatctt ttggcaaata tagactaaac cgaatgtcat catttactaa
    40381 gtcgatttta tctgctttaa tatacatccc gttttgcatt cggaattgat ccaacctaag
    40441 catgatagtc agatcatctg tattgacttc gatccaatct ggtaatttat agtttctctt
    40501 gatcatattc atcacatctt tgattggcaa actcaatgtt ccgatagaaa gacttctagc
    40561 ttttagttgg acatttccgt tttccatcac atacggatca aaatataaat agaaatcgat
    40621 aggaaaacct agtacttcga aagtaccatt gagtagtgct tcattttcca aataaaattt
    40681 atattcaata tcactatctt tttgatactc actaaggaaa aagctgatga tttgattgac
    40741 tttttcttta tttgaattga tcgttaagac aggatctcct tgtctttccg taagagctgg
    40801 tatttctggg agttctggtt cccgattagc aaaaatacgg ctgcctaaaa atacggtcga
    40861 accaagtact accccaagaa ggataaggaa ggcgaatttc cagtaatttg ttttctttgt
    40921 tttgtttgaa gatacgtcag atcttgtttt catgtttatt gatcatcctc cttctctaac
    40981 cattggtttt gtgtctcgat cagctgatct ctcactgcat ttgccatcaa ttgataacct
    41041 aaattatttg gatggaaatg atcttcttca tagagcacat tatttttgat gccatttaga
    41101 ttttctgtcg tgctagttgt ttgatctgtt ccttcttctg tgacacctac ttcctgattc
    41161 aatccttgat aaagcaaatc attgattggg ataaagtagc agttcggcat tttttttgtc
    41221 accgtttctg ttcctttgtt ccaattgtta acaattgtct gcatgtcagt gatctcagga
    41281 aagttcaaat aaaatggatt gtagatgcct aaaatgtaaa taggtgcggt tttattgagg
    41341 gatcgaaatt cttccaatag ttctgtgaca ttttcctgat agtttttcag tggcttttta
    41401 aaggaattga ccgttaaccc gaataaatta ttttggataa ctttcatcaa atcattaccg
    41461 ccaacagtca gtgtgataaa atcagctgtt ttgatattgt ttcgaatttc ttcttttgtt
    41521 tttactcgct ttaagatctg gtcacttcgt tcaccattta caccatagtt ttctgtttca
    41581 accgcggtca aattataacg gtcttttaga tcatttgcga caaggggaac gaatcctcct
    41641 tgcttggttt gatctcctac tccttcagtc agcgaatctc cgatagctat gtagtgaagt
    41701 ttttcttttt tatttggatc ttctctcaca gtagttactg gtttcattag tgggccagct
    41761 ttcggtatag aagcagctaa acctgcatag atgatgatcg caattaataa tgggaacaaa
    41821 acgaggatca aatgtcgttt cgttaatttc attttttcac ctcttgtatt cgattggttc
    41881 taatgttatc aaaaatttta tcaaaaaggt agtctttatg aaaaaagaaa acaattattt
    41941 tcctaatttt ataaagaaaa agagaataag ctgcaagcct ttcaggctga gggcttatcc
    42001 tcttttcgac taatctacat aatacatgat tgcaaacgcg tctttaccag tatgcgtagc
    42061 gataaccgga ttcgtatgca gtacagggat atgcatgtcc gggaataatt cttgcaaacc
    42121 ctctttgaat tcttgcgcca attcttttgc atccgcatgt gaaataccga tttgtcgcac
    42181 atttggcaat tctttcagtt catttttcaa attattaaac catttatcga acgttttctt
    42241 tcctcgcccc ttagttacag ggattaattc agaatgggcg aaattcatca ccacgcgtat
    42301 gttcaaaaca ctagacagca aaccagttgt tcggctgatt cttccacctt ttaccaagtt
    42361 atctagtgtg gatattccga tgtataattt tgtattgtct tgtacttttt tgacttcttc
    42421 aaggattttc tctactgttt taccttcttt tgctaattca gctgctcgaa ttacctgaaa
    42481 agataatcct tggtcagtgg tatcactgtc gataaccgtt actttcgttt ttgttagatt
    42541 actggcttgt cttgctgctt ctactgttcc actcaagcct tttgtcatat ggatcgaaat
    42601 cacttcactg ccgtcttctc ctagctcatc atacatcgag atgaattctc caattggtgg
    42661 ttggcttgtt ttgggcagat tttttgcttt cgccatcatt tccataaatc tttcgccgtc
    42721 tagttggtca tcatcgggat atactgttcc gtcgatcatg atggatagcg gcatgacacg
    42781 aatgcctaaa gcatcgcgta catttttttc catcgtacat gaagaatctg ttacgatttt
    42841 tacatttgtc attattttct ctctctcttt ctttaacaag atgccttatt catgttaaac
    42901 tacatgtaag acaatttcta tttttagtat aacagacaaa taatgatttt tcattaatta
    42961 cacctagtaa aggagccgtt ttcatggaaa aaacgaaatt taatcgaacg tatgaaatat
    43021 taaatgaagt gtttaatgca gtcacccatg gaattgggac tggattgagt atcgcgggac
    43081 tagtggttct tttagtaaaa ggtgcccact tgcattcctc cctccatatt gtctcttatg
    43141 ctatctatgg atcgatgatg attcttttat ttttaacgtc tactttgttt cattcattga
    43201 tttttacaaa agcaaaaaag gtgttccaag tattcgatca tagttcgatt tttcttttga
    43261 ttgcaggaag ttatactcct ttttgtttgc tgagtatccg aggatggcta ggttggactt
    43321 tatttgtatt aatctggttg tttgcgattc ttggcattat atataaagcg ttgacgttgc
    43381 ataaacggga gagagtatca aaagtatcta cgatcatcta tatttttatg gggtggctct
    43441 gtgtcgtggc tgctgttcct ctttatcact ctcttggaat gactggtgtt attttgatgg
    43501 tagcaggcgg gctttcttac acgataggcg cattctttta tagcttgaat tctatccgct
    43561 atatgcatgt tgtttggcat ttgtttgtta tgttaggtgc aggttttatg tacttctctg
    43621 ttttattctt tacttaataa aaaaaataaa gctatggatg ggacagctct aaataacagc
    43681 tagtctatcc atagcttttt tatatcgtca attcgcctgt cccgcttttt acaggattct
    43741 cattacgctg atacgtttca aattgatgcg gataacgatt tttttcatcc atttctcctt
    43801 gactagtatt gatcagtgac caatcagacc agtcaacagg tggaaaataa gcatctccat
    43861 cgaatacatg atggatgact gtacggtata atatcgtaca aaatggcaga aattcttgat
    43921 aaacagctga ccctccagcg atgaaaaaga taccgtctgt ttctttttcc agagcaagca
    43981 cgtcttccac actatgcatg acatgcacgc cttctgcttt ataggaagaa tctctcgtca
    44041 aaacaatcgt ctgacgattc ggcaacggac ggctacccat cccttcgaat gtttttcgtc
    44101 ccatcactag tgtatttgct tctgtcattt gtttgaagaa tttcagatca tttggcaaac
    44161 gccaaggaag acggtcttct tttccaatca atccgttttc atcctgtgcc caaattgcag
    44221 ctaacatttt ctcatccttt ctgattctaa acagcgatag gagctttgat cgccggatgt
    44281 gggtcatatc cttctaattg gatatcttcc atctcaaaat caaatactga ctgcttttcc
    44341 tgattcaaaa ctaaagtcgg aaatgcgcgt atttctcggc tcaattgttc tttcatttgt
    44401 tcgatatgat tgatataaag atgagcatct cctaatgtgt gaacaaattc gccaaccgct
    44461 aaacctgttt catgtgcaat taggtgagtc agcaacgcat aacttgcaat gttgaacgga
    44521 acgcctagaa acacatcccc actgcgttga tacaattggc agcttagccg tccctcttga
    44581 acataaaatt gaaacatcgt atgacaagga ggcaaagcca tgctaggaac atcttccgga
    44641 ttccatgcag aaacgatcaa tcttctagaa tcaggagtct ttttgattgc ttcgatcact
    44701 tgtttgattt gatcgataaa gccaccgtct tttgtttccc agtgacgcca ttgatagccg
    44761 tagatgtgtc caagatcgcc gtatgtttca gcaaaggaat catcggttag gatcttctcg
    44821 caaaaaagct tgctctgctt tttatattct tcattgaatt caggatctgt caaacatcta
    44881 tggccaaaat cagtcatatc tggtccatta tagtctggac ttttgatgta gcgttcaaat
    44941 gcccattcat cccaaatatg gtttttattt tgtaatagat agcggatatt cgtatctcct
    45001 tttaaaaacc aaagcaattc gcttttgatc aatccaaaag gtactcgttt cgttgttaac
    45061 aaaggaaacc ctttttgcag atcaaaccgc atttggtatc cgaataagct taatgtgcct
    45121 gtgcctgttc tgtcttcttt acgatgccct tcttccaaca attttcttcc taagtcaaga
    45181 tacgcttgtt ccatcctttt tcctcctaat cttctaccca ttcactcaag tattcccacc
    45241 gtgccatttt ttcttcaagt tgtgcttctg tttcagatac gtcgttttgc aattcttgta
    45301 atcgagtgaa attatctcct tgatgattca tctcttcttg gagcaatgag attttttctt
    45361 caagttctgc aatctcatct tcaatcgttt cccattcttt ttgttccatg taagataatt
    45421 tcttcttttc agcaggttcc ttgctctgta tttttggttt cgctttttca gcaggctgct
    45481 gggtctcttt ttgcttcagt aaataactgg acatgtttcc gtaataaagt tcttgttttc
    45541 cgtttccttg gaatactaat aacttatctg ctaccttgtc caagaaataa cggtcatggg
    45601 aaacagtgat cacagcacct ggaaaacttc taaaataatc ttccaaaatc gtcaatgttg
    45661 ctatgtccaa atcattggtc ggttcatcca ataataaaac attaggttgc tgaatcagca
    45721 gtttcaacaa aaataaccgg cgtttttctc cgcctgaaag tttgcctatc agtgtcccat
    45781 gcataaatct tggaaataaa aatcgttcaa gtaattctgc tactccgatt tgactgccat
    45841 ctgctgtttt tgcttcttca gcagcttctt gtaagtaagc aatcatccgt ttatctggtg
    45901 ccatttcttc attttcttgt gtataatacg caagatgaac cgtttcaccg atagacattg
    45961 taccgctatc caggggaatt ctgccagcta gaatattaag caatgtcgat tttcccgcac
    46021 catttttacc agtaatacct agtctttccc gagattgaat caataaatct aaatgttcta
    46081 gcagtgtttg gtcatttata cggtaactgc catctttgat ttccagtact tttttcccta
    46141 aacgttgtgt cgctaggttc agctctaaat catcttcttg gtttacttgg tacaagttct
    46201 cctttagatc ttcgaaacgg ttgatccgtg cttgctgctt ggtgccacgt gcctgtacgc
    46261 cagccctcat ccaagctaat tcctgtttat aaagccgctt gcgcttttct tcttgttcta
    46321 cttctacacg atcacgttct gctttttcta agacgtaagc ttcataattt cctttatact
    46381 cgtataattt tccaaatgaa agttcgaaga ttcggtttgc tactctatct agaaaataac
    46441 gatcgtgggt aaccatcaat agtgcgccac ggtattgttt caaatagttt tccaaccact
    46501 cgatcgcttc ataatctaaa tggtttgttg gttcgtctag taatagtaaa tcgggttcat
    46561 caatcaacac ttgcgccaga ctaactcgtt ttttctgacc acctgataaa gtactgattt
    46621 ttttatctaa ttcactgatt cctaattttt gcaaaataat ctttgcgttg gtatctgtag
    46681 tccaagcatc ttctttattc atttgttctt ctgctttagc ataacgtttt tgcacatcag
    46741 ggtcttctcc gttttcccct agttcgatca atgcttcctc atatgctcga acagtttgga
    46801 tcaaggggct gtttccttga aagactgctt ggagaacagt taattcatcg gaaaattcag
    46861 ctgcttgaga aagataacca atacggtaat cagttggata aaacactgtt tgccgatcac
    46921 cgtcgctgct atcgataccg gcaataatat ttaagagact tgttttaccc gtcccgttcg
    46981 tcccaatcaa cccgatacgg tctttttcgt ggaccaaaaa agaaatctgg tcaaacaaat
    47041 ctttttcacc ataagttttt ttgaggtcag ttacttttaa ttctttcaac atgttccctc
    47101 cttatcttgg atattgtatc ataaaaatag tgaacttcag gaaaattttt ttggtatttg
    47161 ttctttttgt gttctcaaaa aaagaacagg accgattcga tcctgttctg atatgttttg
    47221 ttttttataa aacttgaaaa tttttacctt tttattttat tggactcgtt ttttttgact
    47281 ttgctcgaaa cgcaaatcgg aaagaaaagt tatcagatgg tttgttcatc gtataagatt
    47341 ctaacaaatt gatattcctg cgatagctgt tcgcagaaaa cgtcgtgatt ttttcagcaa
    47401 cttcgtattc atcaatgatt tttctttcaa gataataacc tcttagcatt tttttcgtaa
    47461 acagactatc ttgctggatc atccacgaag aaatcaaatt ccccgagttc atttttattc
    47521 cttcaagttt gcgttgctgg ataaaaaatt gaaccatcgt ttcatcataa atatcagtca
    47581 agttatctaa actttcaata atcaactgag tatttttttg atatgtctct ctgatttctt
    47641 ggatatcttc atcactaata aatgtctgac gatcagcata tcttctttgc caaaacattt
    47701 tcggatggag aacgattcgc attaacctac ggacaacaat gaaccaaaag ccgataaaag
    47761 acaaaatctg gcttgtgata gaatgttcga atcgagaaag aaaacgggag taaaaacgat
    47821 aaccattaga agaaagcttg cccgaacgat aactttcatc caatccatcc cgttcgatcg
    47881 acaaaatcag tgcttgtatt tcttgtactt cttgcttttc atcatcggtt aaatcttcca
    47941 agtacagatc acgtatccgt tcttgataat tttctatcac tgcttcagtg gctaaaaatt
    48001 cttttgtatt acgatcaatt tcctttattt cttttcgcaa aacttcaacg acctcttcta
    48061 aaatcatcaa agcattcaaa tccgtgcttt tcgcttcctc tgtttccgtc agcataggca
    48121 agacaatgat ccctatgacc aaagtcacta agatgacacc cgccgtcaga aacaaaagca
    48181 aagaccgctg gtaaaacatc atattattga ttgaaaatgg caaaataaaa atcgtagcca
    48241 aactgactgt tccctttaca ccgccaaatg ttaagatcaa gatctcgttc aactgttttt
    48301 tgaacttttt actgccatct ttgaatacat aaaaaagact gatagaaatg aatctgatca
    48361 caaaaagcat gacagagatt aatacgataa tcgctaataa aagaccgttt ggatataaac
    48421 cgtctcccca tactggcgag aacacttgcg tcaattcgat tcctaaaaat ataaatacta
    48481 atgcattcag tgtaaaagca atagttgtcc atgtactgtg ggacaagctc gacaattctg
    48541 catcaaacac agagattttc ctaaaaccag aagcttggag aatacctgct gccactgcag
    48601 caatgattcc agatacatca aatgcctctg ccaatacata ggctagaaaa ggaagcaaaa
    48661 gttcgatcag cagataccct gtgacatctt gtgctgatgc tttttcgatc aaatgaatta
    48721 ttttttgttt gaaccagaca agcaaaaagc cgatcaaagc tcccccaata ctagaaacta
    48781 ctagactcat ccccgcgttt actgctgaaa aagatccggt gatcagcgca ccaagagcaa
    48841 actggaaggc agtaacacca gatgcatcat tcaaaagacc ttctccttcc aaaatatgca
    48901 tcgccttttt agggatattc actcgtccag aaagagaact gactgctacc gcatctgtcg
    48961 gacctaacgc tgctccaaaa gcaaagcagg cagcaagtgg gacacttggc aacaggaatg
    49021 ataacgtcgc acctaccccg acaagggtca aaatgactcc tccaaatgcc aagaacaaaa
    49081 ttgtcccgaa atttttgaga atcgaagaaa tatctgcttt ttctccttct ctaaataaca
    49141 atggtgcaat aatcataact aagaacaatt caggttcaaa atcgattgat tgtccccact
    49201 ctgtcagacc taataccact ccaaggaaaa tttggatcag tggagctgga atcattggca
    49261 aaatgcggct agctatgttc gataaggtga tcgttactgc aaatacaata actaactcag
    49321 caaattccat cgtccatccc ctttattttt tattttgtgt aagcattttt aaaaattgtt
    49381 cttttttctt taaaattttg gtttcgacta cttcaacctg tgtttggttc ccctctaatt
    49441 cacactgtac acgttttgac tccaaacgaa gcagatcatg tttcagacgt tccaactgac
    49501 gatacatcaa tatatttctt ttacgcaact tacaaagtat ttgacggcgg tcatccatcg
    49561 aaagggcgcc atagcgatca tgcaacagtt ttttttgttg ttcaaaactc tctctcattt
    49621 tccagatctc ctatacacaa acttccatca ttatagcaaa gttctttttg gatgaaaaat
    49681 atttcattgt ttcatcgttt attgctagtt agaaatttcc ataaattttt caacgcctca
    49741 ttctattcca aatagtatca gatatcaagt aaaacttaag aaagataaaa gtttctgaca
    49801 aaaggatgtt tactttccca ttcctgcctt tcttgttctt ttatcacaac aaaaaaatgg
    49861 ggctgcgaca aaaatcttgt cacagtccct tattctgaat aaacggtgtg gaagagacag
    49921 cctatcagta gtaataagac acatctcttt cacagcctca tttttgcgta aaaatcgatt
    49981 tattcgaaaa attccccgta tacatcttct acacgttgat ctggattgat cacgatatac
    50041 aagttacctg ttttttcgct gatttttgtt gattgatatt gattgtctaa tccttctgtt
    50101 cctttatcta gatatgggaa gtacacaaga tcaggtgtgc catttcggta aaggatttcc
    50161 attcgctcga tatcttcgta tttcaatgcg cgattaaaca tgcccatttc cagtccgcct
    50221 aggttgatat catgtgtcgc aactgcgtcc ccttcatgga agatttcgat tttaaatcca
    50281 gcacacggat ggatttcaac aaattcactg ccattgattc gtccaaaact tgttgtgatt
    50341 tgtttgatcc aaagatcgcc gatatgacgg cggttgatcg tccaggtttc tccatttcta
    50401 aaataaaatt ttagcgctgt catttcttta ctcattaaaa agactccttt atgatgtaat
    50461 ttattcttgt actacctcag tttagcacaa atttatgtaa gtggtcacat cttatgtttt
    50521 ttcttctaat gacgtatctg cccactttaa gtagccaaca aagctgagca gatacagtct
    50581 agtgtttttt aaatcaattt ttctttcgat aaaaaatcca aaacctgttt tttatcattt
    50641 tttattcttt gttctacgac ggctttttca gctaattgca aagcttcact aacccactta
    50701 ccaggttttt ttccagtttc ttctagcaag attttaccat ctactgctaa ttcgcttaat
    50761 gacttgatag gtaaacgatc ataggattct cctacggcat ccatctgagg tgtttcgtca
    50821 aaatagatca tcaattcttc tacttgcagt gcatgttttt tgcctaagaa gtacaattcg
    50881 aatggttcca aagctccagt ttctcgttgt cgtagtcctt ggacaagtgc ttgaacgtct
    50941 ttaatcattt ggttagaaca cttccacgat ttcaaaaagg aacgaatctc attttctttt
    51001 agatccagtt ggctgatcaa taatgcccat gcttggctct cttctttcaa tgggacggat
    51061 ggtaattcag caaaacgtaa aagtgcttcg ccttcttctt tcaaaccggg acagcaaatg
    51121 tagcactctg tttcaataaa tgcatggatt cccgcggccc gttcatttcc caagagcatc
    51181 ttgatgaatt ccacatttat acgttctaca gatattttac ctaatagctc gtggttttct
    51241 ttgatggcgt agaaggtttc ttcctctaat ttgaacccta gttgactgac aaaacgcaac
    51301 ccgcgcatca ttcgtaaggc atcttcatgg aaccgctcat gaggattgcc tacagctcgc
    51361 aagatctgtt cttctagatc ttgcagacca tcgaacaaat cgatgatttc tccatcttct
    51421 ttcaaagcaa acgcattgat cgtaaaatct cttcttttca aatcttctgc caacgaacga
    51481 acgaattcga catgatctgg tctacggtag tcctgataag ttgattccgt ccgaaatgtg
    51541 gtgatctcat attgttcatc attttctaat accaacacag ttccatgttc gatcccaata
    51601 tctatcgttt ttggaaaaag ctgtttgatt tcttctggaa atgcgcttgt tgcgatatcc
    51661 acatcatgga ttggctggtt cagcaagata tcacgaacac ttccacctac aaaataagct
    51721 tcatatcctg cattctctaa ttttttcaga actggaattg ccttttggta ttccagaggt
    51781 aattgtttta atttcatttt tccaaccttt cctgcgtgtt tcttgtcctg agataaagac
    51841 tcagttgcat ggtgactgtt tgacaagtcc gtttcagagt cttcaaggcc aggaccactt
    51901 catcttgttt actcgtcctt acgctcaaag cgattatggt ctctttgatt gaatttttcc
    51961 atgttttttt caaaaacttc agttaagtcg atattcaatg aattagccat gatcatcgta
    52021 acgaataaaa catcaccaag ttcttctgct accgagttaa ctggttcaga agcctttttg
    52081 cttttttctc cataagtgtg gttgacttct cttgccaatt cacctacttc ttcagttaat
    52141 cgagccatct gagctaatgg agagaaatac cccaccttga attgctggat atattcatcc
    52201 acttcctgct gcatactgta taaagaacgc tttttatcca tctttttccc tccaaaacta
    52261 tcttaccaaa actttaacgc aaatcctaga taagagcaat tgagaaaatc gaatttccat
    52321 gctacattta ggaaggaatt tctaaatgga aattctgtga aaatacataa ttgaaagctg
    52381 gaattcatat ggtcaaacga aaaacagtaa aagaagttct ttttatcatt ataggaacaa
    52441 gtatttatgc atttggtctt gtttacttga acatcgctaa tcatttagca gaagggggag
    52501 tctcagggat caccttgatc ttaagagctt tatttggtat tgatccagct tatacgactt
    52561 tattaatcaa catcccattg attttactag gaggaaagat cctcggtaaa cgttccttgg
    52621 cctatactgt tctaggtaca ctttctttgt cattcttttt atggatctgg caaagggttc
    52681 cactagaaat caatttacag catgatctac tgatcgtttc tctacttgcg ggtttagttg
    52741 caggtgtagg aagcgggatc gtctaccgca tgggtggaac aacaggcggc agtgatatta
    52801 tcgctcggat tttagaacaa aattacggca tcactatggg gcgttcccta ttggcatttg
    52861 atatcatcgt cttacttgct tcattaacct atatcgactt gaaacgtatg atgtatacgt
    52921 tgattgtttc gtatgttttc agtcgtgtga ttgattcgat cttagatggc ggatattctg
    52981 caaaaggtct acttgtcgtc tccaacaaaa gcgaagagat tgcaccacta ctgatgaccg
    53041 gtctgcaaag aggtgtgact ttcctttctg gagaaggcgc attctctggt aattcaaaaa
    53101 aaatcatcta tatggtcgtt agctctagtg aattaactga agctaagagg atcgtccacg
    53161 agattgacga aaaagctttc ctttcaatca tcaatgtgca tgaagtggaa gggcaaggct
    53221 ttacttattt gaagccacag acaagattac tgaaaaaact ataagaaaaa agacaaagat
    53281 aggctatgag gaaagattcc acatccagct gacctttgtc ttttttagta ctatactatt
    53341 tttaactaat tgttatgttc acttacccgg ttacttttct tttgtgtctg caaaaggatc
    53401 tttcggttaa cttcatcaga taatttcaaa aaagcatccc tatctccatc ttctagtgct
    53461 tgatcgattt gagcataaag catttttagt tttgcctctt cttctttttc ttgaaaatat
    53521 cgttcaatta attcagtatc ttcttcactg actgaagaat cccaagaaga aaatggattg
    53581 tcttctaaga tagatagata ttctcttgtc tgccaagcat tttcgaatat acattccaca
    53641 tataaaggct ttttccaatt caaacggatt tcatgaaaaa tctggtctgt gtccgtaaat
    53701 tcttttccct gcaaaaacaa tttcatgggt tccccttcaa cagatagatc actgatctgc
    53761 agtcctcgat ccgcaaaatt cgccccttca acaaagtgga cattgcttaa aatcgcttca
    53821 tgattggcaa gataattcaa gatccaaaaa acttctcttc ggctaaaaga tacatgattg
    53881 accatccacg ttaaaaaatt cttcttttcc cgtacatcaa ttagcatttt tctcacctct
    53941 ctgttaggtc atctaataat gacagtgcct ccatatctcc tggttcaagt gttaaataat
    54001 aagtcaataa ttcttgcgct cttttcagct gcccttcttc tcttaagaaa aaggcatact
    54061 ctttcaagaa atctggttca tgtgatagtt catgataagc ctgttcatag tgtacagctg
    54121 caacggtaaa gtcttctaat tcattataag catgggctag gttccattct gcataaggat
    54181 tagcagtttc ttccatctga ttgatcactt gtatcacatc ttcatatctt tcatcatcca
    54241 agtaaagatt acttaaagta agtaatgttt catcttgttt gtctcctact tctaaagctt
    54301 tcagtaaaag ttcttctgct cgctgtctat catgcagacg gaaagcattt tccgaggcca
    54361 ggtgataaag ttcgacttgg taaggatttt ctttgattcc ttcttctaac actgtttgtg
    54421 cttcttcaat catttcttct tcttgaagag cttgtcctag atatagatat aacgattgat
    54481 aatgcggatt aacttctcga agttcttcca gatagttgat tgcctgctga ttttctttca
    54541 attgaagatt cgtaaaagct agctggaaca gtcgatcatc tgtcctttct tctttcagtg
    54601 cttcttctaa aggtacgata gctgcttcga attctccttg catacttaag gattgtccta
    54661 aacgttcctg catcgagatt cctgaaattt catttatccc gcttgccaac aatgtttcat
    54721 aaaccactgc tgcctctttg aaacgatcaa ctgaaaaata caattcagct agcgcaaact
    54781 ggatcaatgg ttcatcagga agcaacccag ctgcttcttt caattttgct tcactcactt
    54841 cagggattcc gataacttgg tacaaatcag ctatcgccaa taagctttgc ggatagtaat
    54901 cactttgctt atccactttt tccaggtatt caaaagctaa gtcgatctca ttatcttcga
    54961 ttgcaatttc tgctaacggg atgttcagtc cgtcattttc tgggtattgg ttgatcagtt
    55021 gttcaaaaat ctgttttgct tcgatcaaaa agccaatagc cagcaattct tcgcctagtt
    55081 cagctaatat atctgctggg tcttctttta atgctttttc taaaaagatt tgtgcttgtg
    55141 acaagtcttc atctgataaa gcttgcaaca ttttttcgct atttgtattc atttcaattc
    55201 cctcttatct cactgacgat ttgttgaaat accgtcattg ttctcaataa ttctttttcg
    55261 tttggatgtt ggtatccgtc tattatacct attttttcta aaacaagtat ttttttgctt
    55321 ttttctgcca aaaaaagaac tttttccaaa tactccatct ttgaaatctg ttccagccag
    55381 tggattggat agccaagcaa gtccagccac acaaaaaagt tttttagttg gaaatcaaaa
    55441 ggatatgctt ggagattcca cacgaaatga aacatcattc ctaaaaattt tttcatacta
    55501 gcagaaagta gatggccatt ttcggtcaga taaaaagctt gttcaaacag tttaccataa
    55561 tttgacaggt tttctgcctc taattgataa aaatagatca tttcttcgat catcccggca
    55621 aacggccgag tcgttaattg ctttttattt ggatagtttt tatacagatt ttgcaaaaaa
    55681 cgatgatcac aaatcattcc gcaacagata aaagtcaaaa agtcaatctg ctttccgtcc
    55741 acctgccgct cgctgattgt ttgatcataa acgatgcgtt ctggcagatt gatggtttgc
    55801 agcactacac gatttggtag ctgcaaaatc gtccgctgcg gtgttaatgc tcggcttaga
    55861 gaacggatcg atacagggat catccatagt gatgaatcaa gggttgtatg tttttgaaaa
    55921 aaacctgcca gatccatgat cccttcattt ccaaatccga tgataaacat ggattgattt
    55981 tcgggatagc gtttgacgaa atcaagcagg ttctttaatt ctgttaaatg attgcattga
    56041 gtgttggcac aaatatacca gtcattgttt gcttgatttg caaataacgg gttgatctta
    56101 tctgcaaaca aatcataata gcgctgattc gttaaaaata agattggctg atcaatggaa
    56161 agttctctta gctgactgac tagcgtttct ccgtaaaaca ctttcgtcaa cgcatcttct
    56221 acttgataat caagttccat acgcatccct cctcttctta tttttatttt accattagta
    56281 agcaaattct agaaaagata agagcaaagc tcacctcata acttgcaaat aaataaaaat
    56341 taaataaaat acatgtgttt tctatgtatg acatacggat tcggaatctc tgtctcttat
    56401 ttattccttt tctgctagga aataaaaaga aaagcacttg tagccctaga gccacaagcg
    56461 ctttttcaac tgtcttattt aacagcgtct tttaatgctt tacctggttt gaatgcaggt
    56521 actttgctag ctggaatttc gatttcttca ccagtttgtg ggttacgacc tttgcgagct
    56581 gcgcgttcgc gaacttcaaa gttaccaaaa ccgattaatt gaactttttc gccgttagct
    56641 aaagcatctt gaatagttga aaatacagca tctactgctg cagttgcatc ttttttagtt
    56701 aaatcagtag ctgaagcaac tttttcgatt aattctgctt tgtttgccat ggatagattc
    56761 acctcctcca caagagatat gatagaaata tcatttagtt aaaactttct gagtggtcca
    56821 gaagtttaaa aagaaatatt gattaacttc aatattctgt tatcacgata tcatatgaac
    56881 cgcttaatag caaggttttt accaattttc acatgctttt tttagtcata gaaacgtaac
    56941 aaacgaaact gtctttttct tttgaaaaaa aaacgtcgat atggtaaaat gcctattttc
    57001 tcctacgagg gataattcgg atggacgtcc cttcaaaagt aaatgctttt ctgatttgat
    57061 tttctaagaa acgttcataa gaaaaatgca tcaattcctc ttcattgaca aaaacgacaa
    57121 atgtaggtgg tttgacagcg acttgtgtag cataaaaaat cttcaggcgt tttcctttat
    57181 ctgttggtgt tggattgatt gctacagcat ccataatgat atcattcaac acagccgaag
    57241 agatacgaag attctggttc atacttactt gttcgatcat ttcaggcaga cgttccaacc
    57301 gttgtttagt cactgcagaa acaaaaacga ttggagcgta atcaagatac cggaattcat
    57361 cacgaatctc ttgttcgaaa tcacgcattg tattggtttc tttctttaca agatcccatt
    57421 tattcacgac gataataatt ccacgaccag cttcatgggc gtaacccgct actcgcttgt
    57481 cttgttcccg aatcccttct tcagcattca gtaccatcaa aacgatatca gaacggtcaa
    57541 tggcacgcat tgcacgcatc acgctgtatt tttcagtatt ttcgtatact tttccgcgtt
    57601 tacgcatacc agctgtatct atcattaaga atttctgacc actttcagaa acgaagtggg
    57661 tgtcgattgc gtctcgggtc gttccttcaa tatccgaaac aattacacgt tcttctccta
    57721 aaatcgcatt gatcaaagag gatttaccaa catttgggcg accaatcaaa ctaaacttaa
    57781 tcgtgtcgtc gtcctcttct tcagtctctt cagagaaata cttcactgct tcatctaaaa
    57841 tatcaccaat ccctagtcca tggcttcctg aaacaggata aggatcgcct agccctaagg
    57901 aataaaattc atagatatcg tttctcattt ctggattatc tactttattg actgctaaaa
    57961 tcactggttt attacttctg tataaaattt tcgcaaccat ctcatctgcg tctgtcacgc
    58021 cttcgcgtcc gctgactaca caaatgatta catctgcttc ttcaatcgcg atttctgctt
    58081 gatgcttgat ctgatccata aaaggttcat cgccaagatc aattccgcct gtgtcgatca
    58141 cgctgaattc tcgacctaac cattcacctt ttgcataaat acgatcacga gttactccag
    58201 gagtatcttc gacaatcgag atacgctcac cagcgatgcg gttaaaaatc gtagacttac
    58261 cgacgttcgg gcggccaacg attgcaattg ttggatttgc catattattt cctcctcaca
    58321 agtttccaat ctcacttagt ttaacgaatg cattgccaac tttcaagcat agattgtcaa
    58381 ttaaacgaag tatttttatt ccttattgaa atactaatcg cttttcaaaa gaaaa
//
LOCUS       DAIGWC010000008        55809 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.008, whole genome shotgun sequence.
ACCESSION   DAIGWC010000008 DAIGWC010000000
VERSION     DAIGWC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.008"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            2..520
                     /locus_tag="NOB74_000511"
     CDS             2..520
                     /locus_tag="NOB74_000511"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI1219723.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            648..1331
                     /locus_tag="NOB74_000512"
     CDS             648..1331
                     /locus_tag="NOB74_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HCI1219724.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1640..1713
                     /locus_tag="NOB74_000513"
     tRNA            1640..1713
                     /locus_tag="NOB74_000513"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1674..1676,aa:Arg,seq:tct)
     gene            1872..2230
                     /locus_tag="NOB74_000514"
                     /pseudo
     CDS             1872..2230
                     /locus_tag="NOB74_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
     gene            2353..3984
                     /locus_tag="NOB74_000515"
     CDS             2353..3984
                     /locus_tag="NOB74_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HCI1219725.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4046..4687)
                     /locus_tag="NOB74_000516"
     CDS             complement(4046..4687)
                     /locus_tag="NOB74_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCI1219726.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4873..4949
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            4969..5277
                     /gene="rplU"
                     /locus_tag="NOB74_000517"
     CDS             4969..5277
                     /gene="rplU"
                     /locus_tag="NOB74_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HCI1219727.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5304..5648
                     /locus_tag="NOB74_000518"
     CDS             5304..5648
                     /locus_tag="NOB74_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HCI1219728.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5661..5954
                     /gene="rpmA"
                     /locus_tag="NOB74_000519"
     CDS             5661..5954
                     /gene="rpmA"
                     /locus_tag="NOB74_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HCI1219729.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6388..9195
                     /locus_tag="NOB74_000520"
     CDS             6388..9195
                     /locus_tag="NOB74_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI1219730.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9386..9877
                     /locus_tag="NOB74_000521"
     CDS             9386..9877
                     /locus_tag="NOB74_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1219731.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            9980..10969
                     /gene="manX"
                     /locus_tag="NOB74_000522"
     CDS             9980..10969
                     /gene="manX"
                     /locus_tag="NOB74_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HCI1219732.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11002..11805
                     /locus_tag="NOB74_000523"
     CDS             11002..11805
                     /locus_tag="NOB74_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HCI1219733.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11826..12740
                     /locus_tag="NOB74_000524"
     CDS             11826..12740
                     /locus_tag="NOB74_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HCI1219734.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12823..13197
                     /locus_tag="NOB74_000525"
     CDS             12823..13197
                     /locus_tag="NOB74_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HCI1219735.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13336..13581
                     /locus_tag="NOB74_000526"
     CDS             13336..13581
                     /locus_tag="NOB74_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI1219736.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13753..14817
                     /locus_tag="NOB74_000527"
     CDS             13753..14817
                     /locus_tag="NOB74_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCI1219737.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15063..15488
                     /locus_tag="NOB74_000528"
     CDS             15063..15488
                     /locus_tag="NOB74_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI1219738.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15481..15930
                     /gene="nusB"
                     /locus_tag="NOB74_000529"
     CDS             15481..15930
                     /gene="nusB"
                     /locus_tag="NOB74_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HCI1219739.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16027..16881
                     /locus_tag="NOB74_000530"
     CDS             16027..16881
                     /locus_tag="NOB74_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HCI1219740.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            16882..18219
                     /locus_tag="NOB74_000531"
     CDS             16882..18219
                     /locus_tag="NOB74_000531"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HCI1219741.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18224..18448
                     /locus_tag="NOB74_000532"
     CDS             18224..18448
                     /locus_tag="NOB74_000532"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HCI1219742.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18450..19340
                     /locus_tag="NOB74_000533"
     CDS             18450..19340
                     /locus_tag="NOB74_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCI1219743.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19349..20167
                     /locus_tag="NOB74_000534"
     CDS             19349..20167
                     /locus_tag="NOB74_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HCI1219744.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20274..20723
                     /locus_tag="NOB74_000535"
     CDS             20274..20723
                     /locus_tag="NOB74_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCI1219745.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20741..22423
                     /gene="recN"
                     /locus_tag="NOB74_000536"
     CDS             20741..22423
                     /gene="recN"
                     /locus_tag="NOB74_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HCI1219746.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22478..22594)
                     /locus_tag="NOB74_000537"
     CDS             complement(22478..22594)
                     /locus_tag="NOB74_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HCI1219747.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22667..23623)
                     /locus_tag="NOB74_000538"
     CDS             complement(22667..23623)
                     /locus_tag="NOB74_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI1219748.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23794..24162
                     /locus_tag="NOB74_000539"
     CDS             23794..24162
                     /locus_tag="NOB74_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HCI1219749.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24332..24763
                     /gene="mraZ"
                     /locus_tag="NOB74_000540"
     CDS             24332..24763
                     /gene="mraZ"
                     /locus_tag="NOB74_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HCI1219750.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24784..25743
                     /gene="rsmH"
                     /locus_tag="NOB74_000541"
     CDS             24784..25743
                     /gene="rsmH"
                     /locus_tag="NOB74_000541"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HCI1219751.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25748..26149
                     /gene="ftsL"
                     /locus_tag="NOB74_000542"
     CDS             25748..26149
                     /gene="ftsL"
                     /locus_tag="NOB74_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HCI1219752.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26150..28342
                     /locus_tag="NOB74_000543"
     CDS             26150..28342
                     /locus_tag="NOB74_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCI1219753.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28368..29330
                     /locus_tag="NOB74_000544"
     CDS             28368..29330
                     /locus_tag="NOB74_000544"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HCI1219754.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29344..30705
                     /locus_tag="NOB74_000545"
     CDS             29344..30705
                     /locus_tag="NOB74_000545"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HCI1219755.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30731..31819
                     /gene="murG"
                     /locus_tag="NOB74_000546"
     CDS             30731..31819
                     /gene="murG"
                     /locus_tag="NOB74_000546"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HCI1219756.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31834..33054
                     /locus_tag="NOB74_000547"
     CDS             31834..33054
                     /locus_tag="NOB74_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HCI1219757.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33210..34535
                     /gene="ftsA"
                     /locus_tag="NOB74_000548"
     CDS             33210..34535
                     /gene="ftsA"
                     /locus_tag="NOB74_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HCI1219758.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34558..35799
                     /gene="ftsZ"
                     /locus_tag="NOB74_000549"
     CDS             34558..35799
                     /gene="ftsZ"
                     /locus_tag="NOB74_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCI1219759.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35816..36493
                     /locus_tag="NOB74_000550"
     CDS             35816..36493
                     /locus_tag="NOB74_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HCI1219760.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36507..37106
                     /locus_tag="NOB74_000551"
     CDS             36507..37106
                     /locus_tag="NOB74_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HCI1219761.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37121..37408
                     /locus_tag="NOB74_000552"
     CDS             37121..37408
                     /locus_tag="NOB74_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HCI1219762.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37457..38239
                     /locus_tag="NOB74_000553"
     CDS             37457..38239
                     /locus_tag="NOB74_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HCI1219763.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38260..38967
                     /locus_tag="NOB74_000554"
     CDS             38260..38967
                     /locus_tag="NOB74_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HCI1219764.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39229..42027
                     /gene="ileS"
                     /locus_tag="NOB74_000555"
     CDS             39229..42027
                     /gene="ileS"
                     /locus_tag="NOB74_000555"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HCI1219765.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42076..43602)
                     /locus_tag="NOB74_000556"
     CDS             complement(42076..43602)
                     /locus_tag="NOB74_000556"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HCI1219766.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43617..44264)
                     /locus_tag="NOB74_000557"
     CDS             complement(43617..44264)
                     /locus_tag="NOB74_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HCI1219767.1"
                     /translation="MTPNREDYLKIILELSGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44448..44777)
                     /locus_tag="NOB74_000558"
     CDS             complement(44448..44777)
                     /locus_tag="NOB74_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HCI1219768.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            44954..45682
                     /gene="sfsA"
                     /locus_tag="NOB74_000559"
     CDS             44954..45682
                     /gene="sfsA"
                     /locus_tag="NOB74_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HCI1219769.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45698..46711
                     /locus_tag="NOB74_000560"
     CDS             45698..46711
                     /locus_tag="NOB74_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1219770.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46711..47988
                     /locus_tag="NOB74_000561"
     CDS             46711..47988
                     /locus_tag="NOB74_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI1219771.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48051..50753
                     /locus_tag="NOB74_000562"
     CDS             48051..50753
                     /locus_tag="NOB74_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI1219772.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            50905..51222
                     /locus_tag="NOB74_000563"
     CDS             50905..51222
                     /locus_tag="NOB74_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1219773.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51252..51572
                     /locus_tag="NOB74_000564"
     CDS             51252..51572
                     /locus_tag="NOB74_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI1219774.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51680..53140
                     /locus_tag="NOB74_000565"
     CDS             51680..53140
                     /locus_tag="NOB74_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1219775.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53208..53429
                     /locus_tag="NOB74_000566"
     CDS             53208..53429
                     /locus_tag="NOB74_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219776.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53460..53642
                     /locus_tag="NOB74_000567"
     CDS             53460..53642
                     /locus_tag="NOB74_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HCI1219777.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53642..54055
                     /locus_tag="NOB74_000568"
     CDS             53642..54055
                     /locus_tag="NOB74_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HCI1219778.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54178..55359
                     /locus_tag="NOB74_000569"
     CDS             54178..55359
                     /locus_tag="NOB74_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1219779.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55430..55594)
                     /locus_tag="NOB74_000570"
     CDS             complement(55430..55594)
                     /locus_tag="NOB74_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219780.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
BASE COUNT        18441 a         9431 c        12041 g        15896 t
ORIGIN      
        1 gatacctgat tacaaaaaaa taacttttat aagttctata acgttgatta tatttttaat
       61 tcttattctt ctcgtcgtct tggttccccg aatttttggt ttgactcctt atattattga
      121 ggacaaagaa atgagtccat attatgcaca aggaaatctg atatatgtac gaccgaaaaa
      181 tacaaatgag attttagtcg gagatattat tacatattat gaaaattcag gaaaaaaaat
      241 ctcgacgcgt cgcgtaatag ccgttgaaaa caaccacgaa gatttttata caaaagctga
      301 tacaaagact tatattgagc ctggagtagt aaaaaagaga aatattatcg gtagtcccat
      361 ctttcagatt ccatatattg gactagtcct ttcaaaaacg gcatttgcat ggattcaggg
      421 gttattcttt acgattgctt tttgcctaac aggaatcaca gcatggaata cctttgtaga
      481 gttgaaaaag aagcggagac gaacacagaa atttttgtaa gaatgttaaa aacataaatg
      541 tattccagag atccaacgac tcttctgaac atgaaacacg agaaaacact catgcagctt
      601 gtagatttag tcagttgttc gtataatgtg tgaagaggag gagtagtatg cgcaatgaaa
      661 tgatgcatcg tcctgtagtc aaagaagaac tattggattt tatgcgtacc cagcaaaaaa
      721 aattaccggg tgagctaggc aaactggaag aagaagctca tgtagcagaa gtaccagtta
      781 ttccccatga aacagttgta tttttgaaat ttttacttgg acagcttcag cctgaacgaa
      841 tcttggagat cggagcagct atcggttttt catcaagtgt catggccacg acaatcggag
      901 aaaacgctca tgttacgaca attgatcgtt tcgatgtcat gatcgagaaa gctaaaaaaa
      961 actatgaacg tctaggactg acagataaag tgactttgct tgaaggtcaa gcagcagata
     1021 tcttgccgga gttgtctggt ccgtatgact ttatttttat ggatagtgca aaatcaaaat
     1081 atattgaatt tttacctgaa tgcttacgtt tgttaagaaa aggtggcgtt ttgatggtag
     1141 atgacatctt ccaaggagga acgatcttgc tcccagatga agagattccc cgtggcaaac
     1201 gagctatcca tcgtaaatta aatgaatttc ttcgtgttgt gatggatcat cccgatttga
     1261 catcgacaat cttgccatta ggtgatggtg tgatcttaat gacaaaggaa tcagaaacaa
     1321 tcgagttgtg atacatgatt atggcagcct gtagataatc gattgaatcg agggctcaat
     1381 tcgaacttga tgtaaaagtt tctatatttg taagtcaatt aaaggataca ggaaatctaa
     1441 ataaacagga gtagcatgaa gtcaatgtag ctcctgtttt caattgataa ccttagaaca
     1501 gctgaaggag aatgtctcgt tttaaaagat tgatttagta gttgggccaa aataattcat
     1561 tatttgctaa ttaaataact atttcgtatt gacagaagca atttaattat ctataattat
     1621 tgatgttccg ctgattcttg tcatagtagc tcagctggat agagcatccg ccttctaagc
     1681 ggacggtcgg gggttcgaat ccctcctgtg acgctaaaaa accgttagaa actgaggttt
     1741 ctaacggttt ttctttgttt tttgtgccaa tattgtttgt tttcaaaggc aaataaaata
     1801 aaaaaacatc cttatcgagt acaattataa ggagcaaaaa aataaaactc atcagaaaag
     1861 aggaagaaga tatgacgata ctatctagaa ttttagtgac tctagttgca attgaatttt
     1921 tttatatcat gtatatcgaa acggtgagaa ctgattctga cacgacaagt agggttttta
     1981 aaatgagtaa agaagagtta agcagaaaat ctgttcaaac attgtttaag aaccaaggag
     2041 tgtacaatgg actattagga gtgggactac tttatggagc ttatctttct tccgcatcta
     2101 aagaaatcac aagtatgcta ttaatatcta tttttttgtt gcattatatg gcagtttgac
     2161 tagcgatcgt tggattttac tcaaacaagg tgggctagct ctgttggcat tgctttctat
     2221 tttcttataa atatagaaaa aataagaatt tatctaacag gaaactttgt gaaaaatatt
     2281 actttatctc atgaaatatg atattctaat gaatggtatt ttagaaaatt tcatgaaaaa
     2341 ggagttagat aggtgttcaa aaattatgtt tcctcactaa aaaaagaatt ttcaggttat
     2401 gatctttcaa gatttcagaa agatcttttg gctgggatca cagtagctgc tgtagcattg
     2461 cctttagcct tggcttttgg ggtatcaagc ggagctgatg cggccgcagg tttgattacg
     2521 gctatcattg ccggtatcgt tattggcggt ttatcaggcg gtttttatca aatatcaggt
     2581 ccgacaggtg cgatggcagc tatcttgatg tctattgcgg caacaaaggg aatgcaaggt
     2641 gtattgcttg ctactttttt agcgggtcta tttttacttg cagcaggact tttccgatta
     2701 ggaacactga cttcttttat cccagcaccc gtaattacgg ggtttacttc aggtattgct
     2761 atcattattg cattaggtca gatcgataat ttatttggtg ttcactcgga aggtacaaac
     2821 gttattgaaa aactaagtag ttatcaaacg ataggatttc cgataaacac agcctctttg
     2881 atcatgggag ggctagtcat tttagggatg tttatctatc caaaaaaatg ggcgaaacga
     2941 atgcctagtt cgctgctggc tatcattttg gcaacagcag ttatgctatt gttccattta
     3001 ccagtagcaa ctgtgggtaa gattccacaa acattgatca gtagtaatcg tttgaatatg
     3061 ggagatttta gcttttctgc cttgcaacaa gtggcagttc cagctattag cattgcttta
     3121 ttaggaatga ttgaaagctt gctatgtggt gcttcggctg gccgaatggc aaataagccc
     3181 ttagatagca atcaagaatt aatggcgcaa ggaattggaa atctgttgct tcctttcttt
     3241 ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg tggccatcaa atctggtgca
     3301 caaactagat tagctggtat gatacatgca gttgtcttac tgctctccat gcttgttttt
     3361 gcgccagtga tgtcacagat tccaatgcca gcacttgcag gtgttttgat tgtgacggct
     3421 tggcgtatga atgaatggga aacgatcaag gagctattta ctaataaata ttggtcagca
     3481 gttctattgt ttatccttac gatgatttgt acagttatct ttgatttaag tattgctatc
     3541 gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca aaagcgctgc tatcacgatt
     3601 tcattagaaa cgatcgattg gcaaagaatg gggctgccag aaacggaaaa gctgaataac
     3661 tggacagtag tgtatattag tggtccactg ttttttatgt cttcagaaaa actcaaaaat
     3721 aaattggaag aactaaatca tcacgatggt gtcattttct ccatgcgagg cgtaccaagt
     3781 attgatttga cggcacgtgc agtttttgat gaatttcaag aaaaagcaga gcaaagagga
     3841 caaacgatta tctatacttc cttgcagcca gaagtagaaa aacaactttc tcacttgtgg
     3901 gaacatacat tcacgcatca acatcaaaca gttgctcatg cgttgacagc tttacatgcg
     3961 aaatatactg caattagcca ttaaaacaat gaaaaagaac agacaagact gtaaactgaa
     4021 gattttatgg tcttgtctgt tctttttaat attgctgtaa aagtgaagct agtacttgcc
     4081 agtcttgatg gataacaggt acaagggagc gattgtagaa aatagctgct ggatgaaaaa
     4141 gtggaagaat tcgatagttt ttttctgacc attcgtaggc atccttttgt tctgttaatt
     4201 gtaagacagg ccctgtatag agttgaccat gatttttggt aaccgtatat tctttgccaa
     4261 gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa ttttggctgg accttcatca
     4321 gttcgtaatc caatattggt gcatgcgcaa atacttcgga acgagtaggt gtccgatttg
     4381 gataaacagt ttctgactgt tgtgtccgtt tattgatccg atgagtcacg cgatacgggc
     4441 ggctccttac agcactggtg atatacacct cttctcgtgt taagccagtt gaagaaagtg
     4501 cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac atgcgtatca atctctgttt
     4561 tccctggggc ttctcccacg agcatcagtt taggatgaag aggtccttgc ccagcgataa
     4621 atccttctac aggacggccg ttcattctta aagaagcttc ttgtatcagt tcttttgggt
     4681 attccattta tgctcctcct ttttctttta ttataagaat aaaagaaaca caatgcgact
     4741 attttatttg gtagaactgt gaggatagaa aagcagaagt attgcttgaa tttttgtttt
     4801 actttttgat tttaaattta gttgactaac ggttgctgtt ctggtaagct agtactgttg
     4861 taattgtgga ctccacagct acaaccgctc agaacaagta ataagcacag catatgctgt
     4921 cacttcggat ggcgagtcta agtatatcag aaggaggtgc tttatagcat gtacgcaatt
     4981 attaaaactg gtggtaaaca agtaaaagtt gaagtgggac aagcaatcta tgttgaaaaa
     5041 cttgacgttg aagcaggaga aaaagttgtt tttgacgaag ttatcttagt aggcggagaa
     5101 tctacaaaag taggcgctcc aactgttgca ggtgcaactg ttgaaggtac tgttgaaaaa
     5161 cacggcaaac aaaagaaagt cgttactttc aaatacaaac ctaaaaaaca ttcacaccgt
     5221 aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg acgcgatcaa cgcttaatag
     5281 cgtttgagaa agaaggccta tatatgatca aaggaacatt taagcgaaat gacgcaggtc
     5341 agatcgtttc attcactttg accgggcatg ctgatgctgg tccttatgga agtgatatcg
     5401 tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa cgggattgcc tcattagccg
     5461 gttttgagcc gattgttgaa atgaatgaag aagaaggcgg ttatctttat accgaagtca
     5521 cttcaggaat gacacaagaa caaaacaata ttgctgagat tctattagaa aatcttttat
     5581 taggattaca atcgatagaa gctgaaaact cagaatatat ccaaattaaa acaattaatg
     5641 ataaatagga ggtgcagacc atgttgttat ctatgaatct acaattattt gcccacaaaa
     5701 aaggtggcgg ttctacatct aacggccgtg actcagaatc aaaacgtcta ggtgctaaac
     5761 gtgctgatgg acaaacagtt acaggtggat caattcttta ccgtcaacgc ggtacaaaaa
     5821 tctatccagg tgtaaacgtg ggtatcggtg gagacgacac tttatttgca aaagttgatg
     5881 gcgtagtacg tttcgaacgt aaaggccgta acaaaaaaca agtgtctgtt tatccagtag
     5941 ctcaagaagc ttaattgaat cttatgatta aagaggttgt gacaagactt ttgtcacagc
     6001 cttttttgtt tataaaaata aaagttgtag tggaggctac gaagtttact ttgtcttttt
     6061 acacttaata tttttttgcc aatttggaat caggatgttt tgataactat cgttttcaat
     6121 tgatggaagc tatattgttt gctatcagtg aaataattat atggtaaaca gtgttctttt
     6181 tcttgtttcc attataaaaa tcgtatcggg atttttcgtt cttttaaatt gaacatttct
     6241 atctatccgc gtgttatcaa caaaacaaaa tcaggtaaat agttgacgaa acagaaataa
     6301 atacatagta ttatgttttg aagcctaagt acaatagtct atagaaaagg agcgatacca
     6361 ttggcaaaac gcattgaccg aatttatatg tatgtcaaag aaaaaaccgc tcatttaaca
     6421 aaggcagaat atgatcaagg agtaacaaca caggaaattg ctgaagtgtt agggattcag
     6481 cgaacaaata gcagtaaaga tctgaatcag ctagtgcgcg aaggaaaact gataaagaca
     6541 gacggacgac cagtacgtta catatatcaa acactcgtta cgcacgtaaa gccagttaca
     6601 aaacatgtag tcagttacaa agaaacgccg gtctctgaag aaaaaaatac actccaaata
     6661 gatactaagg atatctttgc aaaaatcatt ggagctaacg gcagcatgaa aaattcagtg
     6721 gaacaggcaa aagctgcgat tttgtatccg ccaagaggat taaattgttt gattacagga
     6781 cctaccggat caggaaagac ttattttgca cacgcgatgt atcattttgc aaaagcgcat
     6841 catgtaatag atgaggaaac ggaactgatt gttttcaatt gtgctgatta tgccaataac
     6901 cctgagcttt tgatgagtca tttatttggg tacgcaaaag gtgcttttac aggcgcagat
     6961 gaagaaaaaa tggggattat cgatcaagcg gatggcggta tgctgttttt ggatgagatt
     7021 caccggttgc cgcctgaagg tcaagaaatg atcttttact ttatggatca tggaacttac
     7081 agtcgtcttg gggaaacaac gaaatcccat gaagcaaatg tacggatcgt aggtgcgacc
     7141 acagaagacc caggttcttc tctattagaa acttttgttc ggcgtatccc aatcaatatc
     7201 aaacttccgg cttttgaaaa acgtcctgca aatgagaaag tcgatttagt aaaaatcatg
     7261 attgcccacg aagcaaaccg cacgcagcga aagatttctt tgacagaaga tgtagcaaaa
     7321 gcattgatcg gcagtgtgac ctatggaaat ataggacaat tgaagtcaaa tatccagtta
     7381 gtatgtgcac gaggatttct aaatcatatg caatcacccg aaatctcgat cacaatcgat
     7441 gatttgacag aagggattcg tagcggattg attcaattag caagcaaccg cagtgcaatg
     7501 gcagagcttt ctaaaatatt ggagccaaag ataactgtag caccaaatga tacgatcatg
     7561 aaaatccaat cggactccta tgagttacct tataatctat atgatatcat cggagataaa
     7621 gcagctttac tgaagtcgga tggtttggat caagaagcaa tcaatcattt catttctaca
     7681 gatatcaaca tccatctgaa gtctttctat aaagaccatg gtttttcttt taatgcagac
     7741 agcaaattag cagaatttgt agatccgaaa atcatagaag tgaccaatca gatttatgta
     7801 atggtcaaaa gatctttacc atatgagttt cagcaaaact ttatttatgc tatgagcttg
     7861 catatcagtt cttttttgaa aaaaatcaac ttaggagaag aacggcatac gaatgataac
     7921 atccgtgaga tggcttttga ttttccagat gaatatgctg ttgcgaaaga agtgcgtagt
     7981 tatatcgaaa cgtattttca agtggagatt ccagaaagtg aagactatta cttgaccgtt
     8041 ctactcgtct cgttacgggc aaatcaagca agcggcagaa tcggtgtagt cgttgcagct
     8101 cacggaaaca gcacagcaag cagtatggtc caagttgtcc aacagttgtt agatgcagag
     8161 aacgtacgag cagtagacat gcctttggat atggatccga aaacagcatt ggaccgaatt
     8221 gaacgcaatg tacaagaagt agatgaagga agcggggtca tactcttagt agatatgggg
     8281 tcccttgcgt cgtttaattc gcaaattcaa agagacactg gaattccagt acgtactgtt
     8341 gatatggtaa caacttctct agttttggaa actgtacgaa aggtctcagt attagggaca
     8401 gatctagata tgttgcatga atcattgaaa aattttcgag gttacgcaga aatatcttct
     8461 gtagaatctg ttcaggaagc aaaacctatt cataagaaaa aagctgtttt ggctatctgc
     8521 gcatctggcg aaggtacagc acaaagaatc aaagaattga tcgaacgagc ggtaaacaag
     8581 cgtcaagaaa cagaattaga agttctagct ttgtcgattg tggaagtgaa agaagaactg
     8641 ccagttatcc aaaaagaata tcagatcata gctactactg ggattactga tttgaatatc
     8701 caagccccat ttattccttt agaacgtttt attgatcaaa atatcgaagt cattttggat
     8761 cagttgctga tggaatcaga attggaggaa actgaattca tctccctaga tgaagagtca
     8821 gctaaaaata cgtgtgttga gtttatctct gataacttca tctttattaa tggtagtaag
     8881 ttaatcgatc caatgtggca attttctaca caaatctctc agacgacggg aatcggcgat
     8941 gaagaatatg gattcaaaat caacctagtg atgcacacag caggaatgat cgaacgtatt
     9001 attcggaatg aaccattgac tgtggaagaa aacgaattga caaatacaac gaatgatcct
     9061 ctttatagcc aattggcagc ctcagttgtt ctgttggaag atcagataaa agtaaaagtg
     9121 ccgatagaag aaatgtatta tctgctacgt ctagtccata atcagttaga taaaaaagaa
     9181 tacactgtgc catgaataca caaaaacgat acacttttat agtgtatcgt ttttgtgtat
     9241 tggttaagaa tcctttaaat tcaattagtg tatcgtaaaa aagttggcac gctttttgct
     9301 tatagtagtg tgtgctagga ggtggttgtt cacacagaaa tgataggggt ttctgtgaag
     9361 tagtgaggaa gaaggagttt tgcagatgga tattcgattg gcacgtatag atgatcgttt
     9421 aatccacggg caagtcgcaa cagtttggtc gaagcaaaca ggtgttgaac gtatcattgt
     9481 gatcagcgat gtagtcgctc aagataaatt gagaaagttt ctactaaaag aagctgcacc
     9541 gccggggatc acagcaaatg taataaccgt gcagaaaatg attcaaatct atcatagtgg
     9601 attattatca cgagcaaaag tgatgctttt attcaccaat ccccaagatg ttgaagcggt
     9661 tgtccgctgc ggtgtacagt tgaagtcgtt gaatatcggc ggtatgagtt ttactgaagg
     9721 caaatcaatg attaccaatt ttgtttcagt aaatcaacaa gatattgatt cctttcgtta
     9781 cttgaacagt caagaagtgg agttagagat tcgaaaagta cctgctgaca ggaaaatcct
     9841 tttgatggaa ctactagcga aaatcaaaaa ggtgtagcaa gaatggttgt tggaaaaggt
     9901 caaataattc tgttgtaatg gttagcaatt attaatattt ttgaatttgt tacaacaaaa
     9961 gtaaatagga ggtataaata tggtagggat tatcctagca agtcatggac aatttgctga
    10021 aggaatctta caatccggtt caatgatctt tggcgaacaa gaaaacgtca aagccgtgat
    10081 tttgaaacca agtgaaggtc cagatgactt gagagccaaa ttggaagaag cggttgcttc
    10141 ttttgataat caagacgaag tgttattctt agttgattta tggggcggaa caccgttcaa
    10201 tcaatcaaac acattattcg aagagcacaa agataaatgg gcaatcgtca gcggtttgaa
    10261 tttaccaatg ttgattgaag cctacgcatc acgcttttca atggaatctg ctcatgaaat
    10321 tgcagcacac atcattgaaa cagcaaaaga cggtgtaaaa gtaaaaccgg aagaattaga
    10381 accggcagaa gcaccgaaag cagcagttga agacgcacaa cctaaaggag cacttccaga
    10441 aggaactgtg gtcggagacg gaaaaatcaa atatgtatta gcacgtgttg actcacgtct
    10501 gttacatgga caagttgcga cagcttggac aaaagcagtg caaccaaacc gtattatcgt
    10561 tgtttcagat gcagtatcaa aggatgatct gcgtaagaga ctaatcgaac aagctgctcc
    10621 tccaggtgta aaagcaaatg ttattcctat tagcaaaatg atcgaagtag caaaagaccc
    10681 tcgttttgga aataccaaag cattgctttt atttgaaaat cctgaagacg tattgacagc
    10741 tgttgaaggt ggcgtagaca tcaaagaatt aaatgttggg tcaatggcgc attcggtcgg
    10801 taaagtcgtt gtaagtaaag tattgtctat gggacaagaa gacgttgaag cgtttgagaa
    10861 gcttgaacaa aaaggtgtga aattcgatgt acgtaaagta cctaatgatt cacgcgataa
    10921 catggatgat attttgaaaa aagcaaaagc tgaattagca aaagcgtaat aaataatatt
    10981 aaaatttata ggaggcttat catgtctatt atttcaataa ttttagtcgt attagttgcc
    11041 tttctagctg gtatggaagg tattcttgat gaatttcaat ttcatcaacc actagtggca
    11101 tgtacattga tcggtttagt taccggtaac ctcgaagctg gtatcgtact tggcggtacg
    11161 cttcagatga tcgctttagg ttgggcaaat atcggtgccg ctgtagcacc agatgctgca
    11221 ttagcatcag tagcatcagc aattatttta gttttaggtg gacaaggtgt taaaggtgtt
    11281 ccttctgcga tcgcgattgc cgttcctttg gctgttgcag ggttgttctt aacaatgatc
    11341 gtacgtacaa tcgctgttcc aatcgttcat ttgatggatg cggctgctga agaaggaaac
    11401 atccgtaagg ttgaaatgtg gcacatcatt gctgtatgtt tacaaggggt tcgtatcgcg
    11461 gtcccagcag cagcgttgct atttatccca gcacaaactg tgcaatcatt ccttgaatca
    11521 atgccagcat ggttaacaga tggtatggct atcggtgggg gaatggtcgt agctgtaggt
    11581 tacgctttgg taatcaacat gatggctaca aaagaagtat ggccattctt cgttattggt
    11641 ttcgttgtag ctgcaatttc tcaattaaca ttgattgctc taggtgcttt aggtgttgca
    11701 ttagctctta tttacttgaa cctttctaaa atgggtggtt catcaaataa tggaggcgga
    11761 agcaactctg gtgacccttt aggcgacatt ttgaatgact attaatcttg aaggaggaaa
    11821 ataaaatggc agaagaaaaa atcaaattat caaaaaaaga tcgtttagct gttgcgtggc
    11881 gctctacctt cattcaaggt tcatggaact acgaacgtat gcaaaacggt ggctgggcat
    11941 tttctatgat tccagcaatc aaaaaattat acaaaacaaa agaagaacgt tctgcagcat
    12001 taaaacgtca cttggaattc tttaatacac acccatacat tgcttctcca attttagggg
    12061 ttacattggc tctggaagaa gaacgtgcga atggcgcgcc tgttgatgat gtagcgattc
    12121 aaggggttaa agtaggtatg atgggtcctt tagctggtgt tggtgaccca gtgttctggt
    12181 ttacagtacg tccaatgcta ggtgcactag gtgcttcatt agctatggga ggaaatatcc
    12241 ttggaccaat catcttcttc ttaggttgga acattattcg ttgggcattc atgtggtata
    12301 cacaagaatt tggctacaaa gctggttcta aaattactga tgacctttct ggcggattgt
    12361 tacaagacgt aacaaaaggt gcttcaattt tagggatgtt cgtattagct gcccttgtac
    12421 aaagatgggt atcaatcaaa ttcttaccag ttgtatcaac tgtaaaatta gataaaggtg
    12481 cttacatcga atgggataaa ttgccttcag gtggtgaagg aatcaagagt gcatttgaac
    12541 aagttaataa tggcttagcc ctttctcctg aaaaggtaac aacattacaa gacaacttag
    12601 accaattgat tcctggttta gctgcattag gattaacatt gttatgtatg tggttgctta
    12661 agaaaaaggt ttctccaatc gttatcatcc ttggtttatt cgtagtcggt gttgttggac
    12721 acgtcatcgg acttttataa tccataaaaa tatagctcgg gcgttgtccc gagctttttt
    12781 tatatagtat actgttcata aacaaatatc tggagggaga aaatggttca atcaatcaat
    12841 acaaaagtag acttggtaat tgatgctact tcgtttacgg gtctgacaga ttacgggcaa
    12901 atcatgatag gtaataatgg ttttgagttt taccatgcgc gagatagacg caaatatatc
    12961 caaattccat gggaagaagt ggattatgta ctagcatcag tcatgctaaa gggaaaatgg
    13021 attcctcgat atgccattca aacgaaaaaa aatggtacat acacattttc ttccaaagaa
    13081 cctaaaaaag tgcttcgtgc gatcagagaa tatgtagatg aagatagaat ggtacaatca
    13141 ttgagtttct ttgatgtagt gaaacgtggt attcgtagta tgtttaaacg caagtaaaaa
    13201 ataaagaaaa cttctaagag gaggttttct ttattttttt actttgcaga agaaaatatg
    13261 aaatagcaaa accaattatt tgtccccttt aaatcccata tgctaaaatt gattagcaaa
    13321 gaaggaggtt atattatgag ttggttatgg acattgattg ttggagccgt gatcggagca
    13381 attgcaggtg cgatcaccag taaaggaaat tcgatgggct gtgtaacgaa tatcattgct
    13441 ggactagtcg gttcaagtat tggacaagcg attttcggcg aatggggacc aaaagctgca
    13501 ggtatggcac ttattccatc tattttaggc gcagtgattt tggtagcagt tgtctcattt
    13561 ttctttggaa aacgatcata agtttttaca aaatagtaaa ctaaaaggag ttgcagcgag
    13621 actgtgactc ctttttggct ttatttattt aaaataaaaa gaagttttcc ggaaattttt
    13681 atttaactgt cgtgtacgaa gaaaagtttg ctataatgga aaaaagcgtg caaagaaaga
    13741 gggagtttca ttatgatgct acgtgtagaa aaattgcgca aaaaaatgca agaagaaaat
    13801 ttggattcat ttttggttac cagtccgtac aatcttcgtt acttaacgaa ctttacaggt
    13861 acgacaggat tagctgttat tactttggaa aaagcatttt ttattactga ttttcgttat
    13921 accgagcagg cggcagcgca ggctcaaggg tttgaaatta ttaaaaatgt cggacctatt
    13981 tttgatgagg tagcaaactt agtacgcaaa gaagaactgc actcattagc ttttgaggaa
    14041 acaacagtct catttttaga atattcggtt ttagaagaaa tcatcgatgc ggaattagta
    14101 cctgtttcac agatgatcga agaactcaga gaagtgaaag atgaagaaga aatcgctatt
    14161 atcgaaaaag catgtcatat tgcggatatg gcatatgatc acatcctgaa aatgatccaa
    14221 ccgggcatga ctgagattga agtcgcaaat caactagact tttatatgcg ttctcttggc
    14281 gcttcaggtg tttcttttga tacgatcgtt gctagcggat tgcgttcggc tatgccgcat
    14341 ggtgtagcaa gcaaaaaaat catcgaacaa ggtgacttga tcacattgga ctttggttgc
    14401 tattacgaag ggtacgtttc cgatatgaca cgtacattcg ctattggtga tcctggggaa
    14461 aaattaaaag aaatttatca aatagtctta gatgctcaat tagcagttat tgatgctgca
    14521 aaaccaggaa tgactggtgt ccaattagat gcagttgcta gagattatat ttcaaaacat
    14581 ggttacgggg aagcatttgg acattctaca ggacatggga tcggtttaga gatccacgaa
    14641 ggaccaaacg tttcttctcg tgcagaaaag caatttgtac caggaaatgt gatcactgat
    14701 gaaccaggga tctacttacc aggaatcggt ggagtacgta ttgaggatga cttgttgatc
    14761 acagaagatg gaaatcgtgt gttgactcgt tcaccaaaag aattgatcat cttatagttt
    14821 catcaataga agaagtaagc gtaaaaatca gtgttcacag actttgttat agaaaatcac
    14881 tcgatttaat gatacactat agaagaactt ttaagctgta agagataata aagttgggtg
    14941 ttttctccaa ttcatagcag tttgcagctg atcggcggca gttttcttac cacgtgatca
    15001 ctatgccgca tcatagagaa ttcggatgta tctcgtgctt aggcaaaggg aggaataaat
    15061 aaatggcaga tgaaaaaaat ttgattttaa acgcaaacca agatttagga gagatcgtga
    15121 tcgctcctga agtcatcgaa gtaattatcg ggattgcagc ttctaaagta gaaggcgtat
    15181 acggaatgcg cggaactttt gccagcaatg tcactgaatt attaggacgt gcagctcacg
    15241 gaaaaggtgt ttacttagca aacgaggaag atggcttgaa agtagatctt tactgttatc
    15301 tagaatatgg tgtttcagtt cctaaagtag caatggaaat gcaggaacgg gtcagccagc
    15361 aagtcctttt catgacggat atcgatttat ctgaagtcaa tatccatgta gtagctgttg
    15421 ttcctgaaaa attagaacaa ccaacaatcg aagaactttt tgaagacgaa gaggaagaga
    15481 atgaataaag aattatcaag acacgagatt cgggaaatgg cattgcaggc tttatttcca
    15541 ttagacttca atgcagacct aacaaaagaa gatgcgattt tcaacgcaat cgaattagac
    15601 caccgcgaca tgatcaacga agatgaatca gagtttgttc ctgtttatct tgatacgcta
    15661 gttggcggtg tctgtgcaaa aaaagatgaa ttggataaag tgattgaaaa acatttaaaa
    15721 aacaattggc acatcaatcg gatctcaaaa atggatttgg tgatcttgcg tatcgcgatt
    15781 tttgaaatga cttatgtgac agatgtacca gcggctgttg ctttaaatga agcaatcgag
    15841 ttggcaaaaa catttagtga tgaccgttca cgtaaattcg tcaacggtgt tttatccaat
    15901 gtattgaaag aattagaagc tggggcgtaa gtcctagctt ttttctatga atcatcataa
    15961 acctgttata aatcgggaaa attctatggt agaatgaaaa cacaaaaaat atctgggagt
    16021 ggttagatgg cagaattgat taacggaaaa gaattagctg aaaaaatgca ggcagagatt
    16081 gctgaaaaaa tccaaaaatt gaaagataat ggtatccatc ccggattagt cgttttattg
    16141 gtaggggaaa atccagccag ccaaatctat gtaagaaata aagaacgtgt agcaaaagaa
    16201 atcggaatcc attcattggt agagcgttat cctgagacga tttctgaaga cgaactactt
    16261 gcagaaattg aaaaatacaa tcaagatcct agttttcatg gtatattggt ccaattacca
    16321 ttgccaaagc atatagatga agaaaagatc ctgttagcta tccgccctga aaaagacgta
    16381 gacggttttc atccgatgaa tttaggcaga ctccttgcgg gtaaaccgga caagattcct
    16441 tgtactccat acggcatcat gaaaatgttt gaagcttatt ctatcgatcc ggcgggtaaa
    16501 cgagcagtag ttatcggacg aagcaatatc gtcggtaaac cgatggctca gctactcttg
    16561 atggcagatg caactgttac tgttgctcat tctaaaaccg aaaatctggc tgaactggca
    16621 caagaagcag atattttagt cgtagcaata ggacgtggac attttgtcac aaaagaattc
    16681 gtaaaaccag gtgctgtagt gatagatgta gggatgaatc gtgatgctaa cggtaagctg
    16741 atcggtgatg tgaaatttga tgaagtggag cctattgcag gctggatcac tcctgtgcca
    16801 aagggtgtag ggccaatgac tatcacgatg ctgatgtatc aaaccgtaaa atctgccgaa
    16861 gcttttggag caggtgaata gatggcacaa gaatatttaa ctgtcactac attaacgaag
    16921 tatttgaaaa gaaaatttga tgccgatcct tatttagaac gcgtatattt aacaggcgaa
    16981 atatcgaatt tccgtttacg tgccaatgcc catcaatatt tcagcttaaa agatgaccat
    17041 gcaaaaatat ctgctattat gttcaaagga gcattccaaa aattacgatt ccagccaaaa
    17101 gaaggaatga aagtccttgt cgttgggcgt atttcattat atgaagcggg aggttcttat
    17161 caaatctatg tagagcacat ggagcctgat ggaataggtg ctttatatca agaattggaa
    17221 gaacgaaaag aaaagctgat gaaggaaggc ctttttcaag ggcctaaaaa aatgctgcca
    17281 cgtttcccaa agcgaatcgc ggtccttacc agtccaagcg gagcggttat ccgcgatatc
    17341 atcacgacgg tgaaaagaag atatccaatt gtccaattgg ttttgttccc aacagttgta
    17401 caaggaaacc aagcagcgga caatgttgtc aggaatatcc agagagtaga agagatgggc
    17461 aatttcgata caatgatcat cggtcgtggg ggtggttcga ttgaggattt atggccgttt
    17521 aatgaagagc gggttgctcg ggcgatttat caagctaata cgccggtgat ttcatctgta
    17581 ggacatgaaa cagataccac gatcgctgat ttagtagcag atgttcgggc tgccactcca
    17641 acagcagctg cagaattagc tgttcctgtt ttgtcagaag agttgatgcg cattcaagaa
    17701 cggcaagcta gattgcagca ggcgtttgta cgccagatcc agcgcaaaca agaacggttc
    17761 gagcgtgctc gacgttccta tgtatttcgg cagcctgaaa gattgtatga aggtcagacc
    17821 atcaaattag accagttgaa acagcgatta tatcaagcta cacagcaaat ttatcatgcg
    17881 aaagaaaaac aaacgatcgc attaagccac caattggaac aagtggctcc gctttatcga
    17941 gttaaagcag ctcgccaaga aactgcttat ctagaaaaac gcttagaaga gaaaatccaa
    18001 caatatatga aacaacagca gcagcgtttt gctcaagctg ttcaatctct tgatttgttg
    18061 agtccattga aaatcatggg aagaggctac agctatacga cgttaaatga tcaagtagta
    18121 aaaagtgtca ccgagattca tcaaggggat ttgctgacga tccattatca agatggaatc
    18181 gttaaaggac aagtacaaga gatagacaaa ggagaataaa aatatggaaa atccaacttt
    18241 tgaagagtca ctgcaagaat tagaaaaaat tgtcatgcag ttagaacaag gagacgttcc
    18301 attagaatca gctctagatt cgtttaaacg aggaatggaa ttaagcaaac attgccaaga
    18361 tacattagct aaagcagaag agaccttgac gaaaatgatg acagaatcaa atgaagaagt
    18421 tgattttgac ggaaacgagg aaagctgaga tgagattaac tgacttttca gctattcatc
    18481 tacctgctgt agaaaaagaa atcttgtctt ttttagatga gcatacaacg gatagaggac
    18541 tctatgatgc gatgagttat tcagtgaaag caggcgggaa aagaatacgt cccttattac
    18601 ttttaacggc cgttgcttcc tttgatgagc ctattgatgt tcccgtctat caagtagcag
    18661 ctgctttaga aatggtgcat acgtattcct tgatccacga tgatttgcct gcgatggaca
    18721 atgatgatct tcgtagagga aaacctacca atcataaagt attcggcgaa gcattagcta
    18781 tattggccgg agatggtttg cttacaggag cattccagct aatcagtatg gcacacttag
    18841 gtaattctcc taagcttctg ctgcttcagc aattagctgt ttgtgcggga tcacaaggta
    18901 tggttgctgg gcaagctgca gatatcgagg gcgaatcgaa aaagctttct ttagaagaat
    18961 tagcatttat tcatgaaaga aagacagggc atttgattcg ttatgccttg ctggctggtg
    19021 gcatattagc gaagcaacct gaagaaatct tattgctact tcaacgatta gccgaacatt
    19081 taggtttagc ttttcagata agagatgatc tactcgatgt gattggtaca acgaaaacat
    19141 tagggaaaac agctggtaaa gatgaacgta tggaaaaaaa tacttacccg cgtttattag
    19201 gcctagaaaa gacacgtgag gcgttggaga ttgagctgtt atccgccaac aagatcatag
    19261 acaaattaga agaggacgtt ttttcttttg atggcgggct gatgcgccag atgatcaagc
    19321 aatttgatgt ggagaaatga gggaaagaat ggaaaaagaa cgcgtagatg tattagcggt
    19381 caaacaagga ttatttgaaa caagagaaca agccaaacgt tcagtgatgg ctggtttgat
    19441 ttacaacgaa aaaaacgagc ggtttgataa accgggagaa aaaattccag tgagtagtga
    19501 attaagagtc aaaggtaaaa aacttcctta tgtttctcga gggggattaa aattagaaaa
    19561 agcactcaaa gcatttgatc tatctgttga aggaaaaaca ttgttagata ttggtgcatc
    19621 cactggcgga tttactgatg cagctttgca aaatggcgca aaaatgagtt atgctttaga
    19681 cgttggctac aatcagctag cttggaaaat aagacaagat cctagagtcg tcgtaatgga
    19741 aagagtgaat tttcgttatg caaaacccga agactttacc ttaggaattc cagaagttgc
    19801 tgttatcgat gtttctttta tttcactaaa actgatgctg cctccattac atgctatttt
    19861 aaaagaagag ggagaagtga ttgctttaat caaaccccaa ttcgaagcag gcagagaagc
    19921 tgtagggaaa aacggaattg ttcgtgaccc tcagacccat caaaaagttt tagaagacat
    19981 tttgtcattt gcggcacaag gtggatatga tgtgctggaa ttaagttatt ctccgatcac
    20041 ggggggagaa ggaaatatcg agttcttggc tcacttgagg aaagtacccg aaagcggaac
    20101 aatcaattca gctattaata tggcagaagt ggtttcaaat gcacacgaac agtttgacca
    20161 taaataaatt gtaactgtga aaatcaagtg agaagtatgc ggattcttct ttattatacc
    20221 aaggaaataa gctatcattg attaagaaga atatgctaag gagcgaagac gtaatgagaa
    20281 aaaaagatcg gcatcgtttg attactcgat tgttgagtga gcaagatatc cgaaagcagg
    20341 aagaatttgt tgaaatcctg aaaagcaaag gaatatctgt tactcaagct acgatttcca
    20401 gagatataaa ggaactgaaa ctgatcaagg taccggcttc agatggcggc taccgttata
    20461 gcataccagc tgaaacaaac gaagatgtaa atactaaatt ggaaaaacta ttaaaagacg
    20521 ctttcgtggc agttgaccaa atggaaaaat ttgttatttt gaaaacattg ccgggaaatg
    20581 cttcggcagc agcaaatttg attgataaac gttacaagaa agaattattt tcgattatca
    20641 atgatgacga taatgttttg atgattacac gaactgaaga ccaggcagtt ttattgaaga
    20701 aagacttcct gcattacctt taagttgagg agcgaatgtg atgctacaag aaatcagtat
    20761 tactaacttt gcgattattc cggaattgcg gctttctttt cacgaaggaa tgaccgcgct
    20821 gaccggagag actggtgcgg gtaaatccat tattatcgat gctttaggtc tgttagcagg
    20881 aggaagaggt tcaagcgatt atatacgtca aggagcagaa aaatgtgtgc ttgaagggtt
    20941 gtttgaacta ccaaaacaag aaggattctc tgaactgatg gttgaattag ggatcgaaac
    21001 agatgaggac aatctgattg ttcgacggga tatgtcctta actggaaaaa atgtttgtcg
    21061 agtgaatggt catattatca cattagctaa tctgagaaga atcggcagtt atttagtaga
    21121 tatccaagga caaaacgaac atcaggaact gctccagcct gaatcacatc ttgctttatt
    21181 ggatcgtttt ggagatgtag ctttccaaca gaagaaaaag agttatcagc aagaatatat
    21241 ctcttatcgt gagctggaaa aaagggtacg aaaagtgcag caaaatgaaa aatcctatgt
    21301 tcagagaata gatatgctcc atttccagca agaagaaata gctgctgctg atttgcaagt
    21361 cggagaagaa gagaaattaa aagaagaaag agaaaaactt agcaattatc aaaaaattgc
    21421 tgatggatta gctgcaggtt acggagcact gacgaataat gaacaaaaca gtgtagatgg
    21481 tgttggcttg gccgtttcag aactgcaagg gatcgcccat ctagatgtgg agtatgaagc
    21541 aatttatgaa aatatccaaa gtgcttacta tttgctgcaa gatgcaatcg gcgatatgag
    21601 tcgtcagatt gatttattgg agttagatga gagtcgttta gaagaagtta cgcaacgttt
    21661 agaattaatc cgacagttga aacgtaaata cggcgaatcc attgagtcaa tattggctta
    21721 ctatgacgaa atcaccgaag agctagcttc ttctgatttt tcagaaggtc aattggacaa
    21781 aatgaaagag gaactagagc aaaaagagct tctacttcag caacaagccg cagatcttca
    21841 tgaagcgcgt aaaaaaatcg caaaagaatt ggaaaaatcc attctgcatg aattgaaaag
    21901 tctgtatatg gaaaacactg agtttgaggt acgtttctta aaagaagaaa atagacaatt
    21961 gaatcatgat ggatttgacc aaatcgaatt ttacattacg accaatccag gagagccact
    22021 gaagcctttg gtgaaagtcg cttctggtgg cgaactgtct cggatgttgc ttgctttgaa
    22081 aactattttt tcttctgagc aaggtgtgac aagtattatt tttgatgaag tggatacagg
    22141 tgtgagcgga agagttgcac aggccatcgc agataaaatt tctcaaatat cgaaatactc
    22201 tcaagttttg tgcatcactc atctgcctca agttgctgca gtcgccgact atcaatatta
    22261 tattgtgaaa gcagtgattg atggacgtac gcaaacttct gtttcagagt tgaaaacaaa
    22321 agaaagagaa gaagaaattg cacgtatgct ggctggaagt gagattacaa aactcacact
    22381 cgaacatgca aaagaactat tgaaactcgc aaaaaggacc tgagccacct cgcagtggtt
    22441 caggtccttt tcagcagctg atagctatat tttattttta catgacactc attacagcag
    22501 tcaatacaac agatccaatc gttaaaatca gcattgtcca aatgacaaat tttgttactt
    22561 tagcaaaagt acttgtttgt tttttttcac gcattgtttt caacctcgtc attaattagt
    22621 tgattcaagt gtacaatctt ttttccattt ccacaagagg gcttttttat aaaaacttcc
    22681 ctttttttaa ataataggta gttacgatac aaataaataa tgttaataga actagccata
    22741 taaaggcatc atccctttca gcaataggta acttaatgtt cattccatag atactgccga
    22801 cgattgtcgg tatagttaaa ataatcgtta aagaagttaa aattttcata atattattca
    22861 gattattcga tacgattgct gaaaaagtct gattcatttg ttctactagt tttaattgaa
    22921 tgcgagaagt agtcattgcc tgctctgttt ccaccaatac atcacgtaaa tgatttttca
    22981 aagcatgatt ttcttggaaa agtttatttt gcgctagttc tttcaatgca tctaaattag
    23041 cagaagtcgc ttctctgaaa taaacgaggc ttttttggat atccatgatt tgataaagtt
    23101 gtttgttttc agtggatact tgaagtttgg cttccaaagt atcgcattga gattgaagcg
    23161 tagctaaata actgttgtaa gagagtgtga cctgccaaat gaattgaaag aagatattga
    23221 gattaggcga aatatcactt tttggaaagg tctggctaaa gactttcttt aaaaacagtg
    23281 gttcatgatt cgtaattgtg ataagcttct ttttgggcgt caaaataata gagagcgggt
    23341 atgtatccac ttgaaaataa ccgctaggac ttgttttagc aaaaggatat tgtaacaata
    23401 ataacgctgg ctttgtcaac tttgattgat tgaattcttc tgtacgggaa ttttctgcat
    23461 cgtccaatat ggaagtgatg taatctgacg gaatttcaaa ttgatgtgtc agctgatgaa
    23521 tctcttcttg attaggacgt tctacacaat accagatcgt ttggtcagtt tcctttccgg
    23581 tattacgcag tttctcatta tctaatgtaa aatatttgat catgattttc ctcctgttgc
    23641 ctgtttcttt tattataacg gatagggaat tggaatacat ggaatgtgtt tgtaagatat
    23701 agaatataac tgcataaatt taaataaaat gaaacagttg tgtaaagtat atacagtata
    23761 cttgaagcaa cgataaaaaa ggagtttacg ttcatgggca cattcacacc acttatcttg
    23821 ttttggtata tttacccggt aatcgttttg tttggttgcc aatttcttgt aaaattattt
    23881 tcgttaaatc gtcgttttaa aataaaagcc cctgatttgg cgattccttt tttgtggggc
    23941 ggtatgcatg cattgtctag aaatacaggg acaatttcta tcttaccgtt tttctttatt
    24001 tctgttttgc taatgggaat ttgtattgct gttttccaag catattatta tgaagaaatt
    24061 atttatccgc gttatttcaa gatgacttgg cgtttggttt ttctgttgac aatcgtcttg
    24121 tacgctgtct tgatcattgt gaacatactt tcttacctat gaaaaaaata gaaaagctgt
    24181 aaaaagtctt ttaaaaggct ttttgcagct tgatttttaa aaaaatgttt atgaataaaa
    24241 aaagttgttc ccggatttcc cagaaaaggt ggtagaaagt gggggattgt ggtagactaa
    24301 ttttagttag tggaggaatg gggggctttc aatgttgatg ggtgaattcc aacataatat
    24361 tgatgcaaaa ggacgtttaa tcgtgccctc aaaacttcgt gaagaacttg gcgaaaagtt
    24421 tgttctgaca cgcggattgg atggctgtct tttcggctat ccgatgagcg aatgggaaaa
    24481 tctggaagct aaactgaacg aaatgccgtt ggctaaaaaa gacgcacgta cttttgtgcg
    24541 attcttctat tcggctgcca ctgaatgcga acttgataaa caaggacgaa tcaatatacc
    24601 cagcacgtta agaaattatg cagctttgac aaaaggttgc gtagtcatcg gtgtatctaa
    24661 ccgaattgaa atttgggatg agacacgatg gcaagatttt tctgcagcag cagaagagaa
    24721 ctttgacgaa attgctgaaa gtatgattga tttcggacta taagaatagg aagaggctga
    24781 ctaatgactg aaacatttca acactataca gtcatgttga aagaaacggt agatggattg
    24841 aacatcaaac cggatggcgt ttatgtagac tgtacactcg gcggtgccgg acatagtgaa
    24901 tatttattaa gccaactaag ttctaaaggg catctgtatg cgtttgacca agatcaaaaa
    24961 gcaatcgatc acgccaagct gcgtttagct tcttatgtcg aacaaggtat ggtcacattt
    25021 atcaaagcga acttcagaga attagaagaa cgcttgagtg agcatgtaga taaggtagac
    25081 ggcattttgt atgatctagg ggtttcctct cctcagctag atgaagcaga acgtggattt
    25141 agttatcatc aagatgcacc gttggatatg cgcatggatc agtcagctcc tttatccgct
    25201 tatcacgtaa ttaatgaata ttcctaccat gaattagtaa agattttctt ccgctatggc
    25261 gaggagaaat tttccaaaca aattgctcgt gaaatcgaac gagtacgaaa aacaaaacca
    25321 atccaaacaa ctggtgagct tgtcgaaatc attaaacaag tcatcccagc tcccgcaaga
    25381 agaaaaggcg ggcatcctgc aaaaagaatt tttcaagctg tgcggattgc agtaaatgac
    25441 gaactcggtg ccgaagaggc ctctttagaa caggcaatcc ggttattgaa agtcaatgga
    25501 agaatcagcg taatcacatt ccattcattg gaagacagaa ttgtcaaaag tatgtttaaa
    25561 gaatatagta cggtacaaga tctaccaccg ggacttcctg tcatacctga cgaattccaa
    25621 ccagaactga aagtcattac tcgtaaacca atccttcctt cagaggaaga gctaacagaa
    25681 aacaatcgat cacgcagtgc aaagttacgt attgcagaaa aaataagaat gaaagaggag
    25741 tagaatgatg gcagaattaa agaaaatgca agattacgaa tatgatttac ctgaattggt
    25801 ggatcagccg gaacaacaaa tgcctgattc ttcttcgaat caagaaatca ttcttccaca
    25861 atcaccggca aaacgattaa agcagatttc tgctttggaa aaaattgctg tggcaagcgt
    25921 ggcgattgct attgttgctt tatgtgtttt aacagttatg ctgcgcacaa atatcagcgg
    25981 agctgaaaaa gaaatcacgt caatacaaac agaaatcaat gataaaaagc aagaaaaaac
    26041 gagtttagaa caagaaaaaa acgaactttc tcgtactgaa cggattaaac aaatcgcaga
    26101 agaaaaagga ttgtctatta atgacgacaa tttaaggaaa gtgaagtaaa tgagtcttaa
    26161 aaataaaatt cggcggttta tggaaaagaa aaatctaaat ccgatgaaca atcgcaaaaa
    26221 agtaggtatc attttatttg ctacgagtat tggattgttc tttttatttg ccgtccgttt
    26281 ctcgtatatc gttattggag gtcatgttgc tggtacctca ttagctgaaa aaacaaaaca
    26341 gttgtaccaa ggaagtgaag tagtaaaagc aaaaagagga acgatttatg atcgtaacgg
    26401 tgtggcgctc gcagaagatg cctcctctta ttcaattaaa gcgatactct caaaaacata
    26461 tacctctggg gataaaaaac tgtatgttga agaaaagaat tttgataaaa tagcagaaat
    26521 cctgcataag aatctttcta tagacaaaaa agatgcactg aatattttag aggacggcgc
    26581 aaaaaaagag ctgtatcaag ttgaatttgg tagctatggg aaaaatatct cccaagaaac
    26641 caagcaaaac atcgaagcgg acatgaaaaa agaaggtgtc gctggtcttt attttgtcga
    26701 ccatcaggct cggatgtatc caaatggcgt cttttcttct cattttattg gatacgcagt
    26761 tccagacaaa gatgagaatg gcttagttgg taaactaggt ttggagtctg cttacaatga
    26821 tatcttgagc ggtaaagatg gtaagattat ttatcaaaaa gataattttc aaaatcctct
    26881 gccaggtaca gtggcagaag aagaaaaagc tgtcgacgga caagatatct acacgacttt
    26941 agacagcaga ctacaaagtt atttagaaac actgatggat caagtaaatg aagaatatca
    27001 gccagaagaa ttgacagcag tcctgatgaa agcaaaaacc ggagaaatct tggcaatggg
    27061 acaacgacct actttcaatc ctgaaacaat ggaaggattg actggaaaag atgctatctg
    27121 gcgtaatttc ttggtacaag atagttatga accaggatca accatgaaag ttttcactac
    27181 tgcagctgct atcgaagaag gagaattcaa cgagaatgaa accttccaat ctggaaaaat
    27241 ccaagtagaa gatgctacga tcaatgacca tgactttggt gaaaaaggtg tgctgaccat
    27301 gcgtcaagct ctttcatggt caagtaacgt cgggatggtc atactggaac agcgattagg
    27361 cggacgatgg tataactatt tacaaaaact gggatttgga caaagtactc attctggatt
    27421 agatgatgaa gtaaacggtg ctttacctac attaaatatt gtcgaccgag caatgagtgc
    27481 ttatggacaa gcggtaggtg tgacgaattt ccaaatgatg aaagctttca cttctattgc
    27541 gaataacggt acaatgattc aacctcgata tatcagcaaa gtggtggatc cccaaactgg
    27601 agaagagcga acaactcaaa cagaagttct agggcaacct ttttcaaaag aaacaacaga
    27661 aaaagtccgt gaatatatga gagatgttgt cgaaagcgaa aactacggta gtgcttatgg
    27721 tgtatatagt gtacctggat acaatgtatc ggcaaaaaac ggaacagccc aaatcgcttc
    27781 tgatacaggg ggatatcaaa caggagatac agcctacctg tattcgattg tggagatggt
    27841 tccttctgaa gatccagact atgtcttgta tctaacaatg aaacacccta agacatatga
    27901 tcgaatggca ttggctaaaa tcgcaaatcc attgatgaaa cgggcaatgg attttaaaga
    27961 aactgaagaa gattcagata cagaaacaaa aacagaaaaa gtatccgtag ccgattatcg
    28021 taatcttgaa gcggacgttg cagcagctga tgctcaaaaa agtggactgc aacctgtagt
    28081 gatcggtaat ggtaaaaaag tacaaaaaca atctactgcc aacggtgatc agttgatctc
    28141 tggagaaaaa ctgatcctat atactggtgg tgataagctg atgcctgacg taacaggatg
    28201 gtcaaaagca gatatcatga agctggggaa aatcctcggt attgaagtta gttttgatgg
    28261 agatggttat tgtgtcaaac aagaacttgc tccatatgaa aaaatcactg aagacaaact
    28321 tagttttact ttagaagaat aagaagagaa ataggagaga aaagagcatg gaatggacac
    28381 aagcattgat tcccattgtc agcagttgtg caatgacaat tgccgcaatg ccgctattta
    28441 ttggttattt tcaaatgaaa aagcaaggtc aggcgattcg tgaggaggga ccaaagtggc
    28501 acaatagcaa agccggaact cctacaatgg gcggcttagt gtttctgatc ggctctattt
    28561 tgacaggaat ttgggttgga gcttggcaaa aacagctaac tcctactctt ttcatcttgc
    28621 tttttgtatt agcgttatac ggagtaatcg gctttcttga tgattttata aaaatattca
    28681 agaaaagaaa catgggactg aactcgaagc agaaattgat tggacagatt ctagggggaa
    28741 tcatctttta tcttgtttac cgttctgaag gttatccagg tgtattgaat ttcttcggac
    28801 tagatctacc tttaggaatc atttatggta ttttcgctct cttctggctt gttggatttt
    28861 caaatgcagt aaatctgaca gatggcatcg atggattagt tgctggctta ggaagtatct
    28921 cttttgcagc ttacggtcta attgcttggc atcagcatca gtatgatgta ttaatcattt
    28981 gcttaagtgt tttaggaggt ttactgggtt tcttcgtcta caacagaaaa cctgccaaga
    29041 tttttatggg agatgtcggt tcattagcgt tgggcggact tttagcggca atttctataa
    29101 tgctaaacca agaatggaca ttgcttttga ttggtttgat ctatgttatg gaaacagcaa
    29161 gtgtgatgct tcaagttact tcctttaagc ttacaggaaa acgaattttt aaaatgtctc
    29221 caattcatca tcactttgaa atgtgcggat ggtcggagtg gaagattgat acagtttttt
    29281 ggttgatcag cattgtgact tcgttgatca cattatggat cgtttggtag gagatgacgg
    29341 gaaatgaaaa aaatatcaac atatgaaaat aagaaagtgc ttgtcttagg actcgcaaaa
    29401 agcggagtaa gtgcggccaa attattacat gaattgggcg cacttgtcac cgttaatgat
    29461 ggaaaacctt ttgacgaaaa tccggaagca caagagctgc tttctttagg gataaaagta
    29521 ataacaggta gtcatccaat cgaattgttg gatgaagaat tttcattgat ggtcaaaaat
    29581 ccagggattc cctacagtca tcctttagta gcaaaagccc aagaaatggg tattccggta
    29641 attacggaag ttgagctagc ttacgaagta gcggaatgcc caattattgg gattacagga
    29701 acgaacggaa aaacaacgac aacaacgatg acaggactac tactgaatgc aggagcagat
    29761 caaggaattg cacgtttagc gggtaatatt gggtatccag caagtggtgt agcgcaagaa
    29821 gcaaaatcag aagataaaat tgtgatggaa ttgtctagct tccaactcat gggaatcaca
    29881 gatttccgcc ctcatatagc ggtgattacc aatatctatg aagcacatat tgattatcat
    29941 ggtacaagaa aagaatatgt caaagctaaa tggaaccttc aaaaaaacat gacagaaaaa
    30001 gattatctga tccttaactg gaatcagtca gaactacaag aattagcgca aagaacaaaa
    30061 gcacgcgtac tgcctttctc gacaaaagaa gtgttggaag acggtgtgta tgctgacgat
    30121 tactcaatat actataaaaa agaaaaaata atggaaatat ctgaacttgg cgtaccaggt
    30181 aagcataatg tagaaaatgc actagctgct atttctgtag caaaattgta tggtatatca
    30241 aatgaagcta tacgagaaac gttgcatttt ttccatggcg taccacatcg tacgcaatat
    30301 gtaggagaaa tccaaggcag aaaattttat aatgattcaa aagcaaccaa tattttagcg
    30361 actaaaatgg ctctaagtgg atttgaaacg tctaaggtcg tgttattggc tggcggatta
    30421 gacagaggaa atacatttga tgaattaatt ccttcattaa aaggaatcaa agcaatggtc
    30481 gtatttggcc aaacaaaaga aaagttgatg gatgctggaa aaaaagcagg catcgagaca
    30541 atagtaacag ccgattctgt agaacaagca gttcctttag cattagaaaa cagtacagat
    30601 ggtgatgtag ttttattatc accagcgaat gccagctggg atcaataccc aaattttgaa
    30661 actagaggaa acagattcat ggaagctgtg aaccgattaa aatagaaaaa gtagaagcga
    30721 gcgataaaaa atgaaaattt tggttacagg cggaggaaca gggggacata tttatccagc
    30781 tcttgccttt gtcaattatg taaagactca agaaccgaat gctgaattca tgtatgtggg
    30841 agcaaaacga ggtctagaaa acaaaatcgt ccctgataca ggaatgcctt tccatacctt
    30901 ggagattcaa ggatttaaac gaaaaatttc catgcataac atcaagacgg tccgattgtt
    30961 tcttaagagt atccgtcaag caaaaaaaat cctcagtgat tttcaaccag atatcgttat
    31021 cggtactgga ggatatgttt ccggagcggt agtgtacgct gcagccaaaa tgggtattcc
    31081 aacagttatc catgaacaaa acagtgtacc aggtgttacc aataaatttt taagccgata
    31141 tgtggatcgg atcgctcttt catttaaaga tgcggcttcc ttttttcctg aaaacaaagc
    31201 agttcttgta ggtaatcctc gagcacaaga agtagcagat actaaaaaat cagatatttt
    31261 gaaaacattt gatttggatc cagaaaagaa aacagtcttg atttttggcg gtagtcaagg
    31321 agcacttaaa atcaatcaag cagtatcagt ttttttaagt gaatatattc cttcttctta
    31381 ccaagttttg tatgcttcag gagatagata ttatgaagag atcctaaata aaataaatcc
    31441 tgaaatacaa aatattagtg tccagcctta tatcaaaaat atggcagagg tcatggcttc
    31501 cagtgatctg ctggtggggc gtgctggtgc aacttcgatc gcagaattca cagctctggg
    31561 gttaccggca gtgttggttc ccagcccata tgttacgaat gatcatcaga ctaaaaatgc
    31621 aatgagtctt gttcacgcag gagcagcaaa aatgattgca gataatgaac taacaggtga
    31681 atcactaagt cagacagtca acgaaatcat gggtgatgaa gaattgcaaa agcaaatgtg
    31741 ccgagcttct aaagaacaag gaatccctga tgcttcaaaa cgtctttatg acttagtaaa
    31801 acaaataatc aaaaaataaa ggcggtggtc ttagtgagta agaaaaaaga accaaaaaaa
    31861 ttgtctcatc cgtcttctga tgaaaacaat ttgactcctt ggcaaaaggc taaccgaaaa
    31921 tatctggcag aacaagagat gaaaaaccaa gagccaaaaa aagaagacat aacattagat
    31981 acaccccttt cagattctga agaagaaaaa acggttcaag aggaacagca agaagaaagc
    32041 cagtccgaga aaaaaatcga attttttgaa gagatcaagc aaaagaaaaa cggtggacca
    32101 tataacggtt cttttttgaa ccggctgccc aatttaaaaa gtcaacggca caaagtacta
    32161 tttcgtcggt tagctttgat catcactgta ttgggtatac cgctgatttt tttgatctat
    32221 tatgtttctc cttatagcaa attacaagca gttgcagtat caggcaataa gacagtcaac
    32281 agccaagaaa tcatctctga tacaaaattg tcattaggag aaaatgtttg gggacagtat
    32341 tttcatcgat ctacttatat cgatcgcctt aaaaaagcac agccaagaat cgaaacagca
    32401 aatatacatt tcaaagggat gaatgaattc gatttggatg taacagaata taaagagatt
    32461 gctttgatcg caaaaaacaa tcaatactac ccagtgattg aaaatggaac agtattagat
    32521 gaaaaagtag caaatcctac aaaaaatctc cctatcttgg aagagttcaa agactctgca
    32581 aaaatcaaag aattaacaaa gcaatacaat cagttatcat cagaattaca aaaagcaatt
    32641 tctgaaatca agtacacgcc aagagcaagc aataaaaatc tgatccaatt gaatatgaat
    32701 gacggcaatc aagttattgt aaatatcaat aatcttgcga accaaatgaa atattattcg
    32761 caagtagcca aagatatgga tgaaaaaggt gtgatcgaca tggaagttgg tatcttctcg
    32821 catccttacg gtagcactca agaaacggaa gaatcgggcc aatcggaaga aacaactgaa
    32881 agtgaagaaa atgcggatca aacaaacgaa tcaagtgaag aggcagaaac gcaaaaagca
    32941 caaacacctg gatcgtctag cacaaacgga tcatctgatt caaatgattc aagtgaaaca
    33001 agtcaaatag aagataatcc aagtacaact ccgtcaagtt taaatgaaaa ttgataaaac
    33061 aactttaaaa agtaagaatg tactttctaa aaaccagtaa tttatggtag aattggaagc
    33121 agtgaatata tctattaata agtatatttt aaaacggacg ctagttgttc gcttgtatat
    33181 ggaatagtaa gtaggaggga atcccattca tggcaaaaac aggaatgtat gtaggccttg
    33241 atattggaac gacatctgtt aaagttgtcg tggctgaata tatcgacagc caaatgaata
    33301 ttattggagt aggaaacgca aaatcagaag ggattaaccg aggcattatc gttgatatcg
    33361 ataaaacggt ccaagcgata caacgagcag tacgacaagc agaagaaaaa gcaggtatcc
    33421 agatcaaagg cgtaagtgtc ggtttgccag caaacatgct tgaagtagaa aattgccagg
    33481 gaatgattgc agttaacgga gattcaaagg aaatcaccga tgaagatgtc agaaatgtgg
    33541 cttcagctgc ccttgttcgt tcaatacctc ctgaacgtca aatcgtgtca atattgccac
    33601 aagattttac tgtcgatggg ttcgagggaa tcaaagatcc tcgtggaatg atcggcgtaa
    33661 gattagaaat gtacggtctg ttgtttacag gacctaaaac gatcatccat aacatacgta
    33721 aatgcgtgga aaatgccgga ttaatcgtca acgaaatggt gattactcct ttagcgctga
    33781 ctgaatcaat tctttctgac ggagaaaaag attttggtac gatcgtcatt gatatgggtg
    33841 gcggccaaac aacaacggct gttatgcatg ataagcaatt gaagtttacc aatcttgacc
    33901 aagaaggtgg cgaatttgtc actaaagata tctctattgt attaaatacg tcatttaaca
    33961 atgcagaagc gttgaaaata aactacgggg atgcataccc agaacggaca tcaccagatg
    34021 aagaatttcc agtagatgtg attggtcagt cagaaccagt gaaagtcgat gaacgctact
    34081 tgtcagaaat tatttcagct cgaatggaac agattttcaa caaagcaaaa gatgcattgg
    34141 accaaatcga agcattagag ttgccaggtg gcgtcgtatt gacaggcgga gctgctagtc
    34201 ttcctggtgt tgtggacttg gcacaagaaa tcttcggcgt aaatgtaaaa ttgtatgttc
    34261 caaatcacat ggggctgaga aacccggtat ttacaaatgt aataagtatc gtggattatt
    34321 cagcaaactt gagtgaagtg tatcaattgg caaaaattgc tgttacgggt gaaacctcag
    34381 cagctcgtca aatggtagtt gaacaagaaa caacaaacac atatgagagc tatgaagcac
    34441 ctgaagaaac aatctacgat gagccggaac caaaagagtc cggagaaaat gtaaaaaata
    34501 aaatcaaggg tttctttaca aatatttttg attaattcat cctgggagga ataagatatg
    34561 gaattctcaa ttgataataa tatcaatgac ggcgcagtaa tcaaagtcat cggagtcggt
    34621 ggtggcggtg gaaatgctgt aaaccgaatg attgaagaaa acgttaaagg tgttgaattc
    34681 attacagcca acacagacgt gcaagcatta aaaaattcaa aagctgaaac agttatccaa
    34741 ttaggcccca aatatactcg tggtttaggt gctggttctc agccagaagt tggacaaaaa
    34801 gcggcagaag aaagtgaaca atccttacgc gaagctttag acggtgcaga tatgattttc
    34861 atcactgcag gaatgggtgg aggaaccggt acaggtgctg caccaatcgt tgcaggtatc
    34921 gcgaaagaat tgggcgcatt gactgttggt gtcgtgacac gtccattcac ttttgaagga
    34981 ccgaaacgtg gccgttttgc tgcagaaggt atcgctcgtt tgaaagaaaa tgtggataca
    35041 ttattaatta tctcaaataa ccgtttatta gaagttgtag ataaaaagac accgatgctt
    35101 gaagctttcc gtgaagcaga taatgtttta cgacaaggtg tacaaggtat ctctgatttg
    35161 atcacagcgc caggttacgt taaccttgac tttgctgacg tgaaaacagt gatggaaaac
    35221 caaggtacag cattgatggg gatcggtgtg gctagtggag aagatcgcgt agtagaagca
    35281 acgaaaaaag caatctcctc tccattgctt gaaacatcta ttgatggagc tgaacaagta
    35341 cttcttaaca tcacaggcgg tttggatatg acattgttcg aagcacaaga tgcttcagat
    35401 atcgtagcaa atgcagcaac tggcgatgta aatatcattc taggtacatc tatcaatgaa
    35461 gaaatgggcg atgaaatccg tgtgacggtc atcgcaacag gtatcgatga atcaaaaaag
    35521 gaacgcaagt ctagccgacc agctagacaa gcacaaatgc aatcacctgc tcaaaagact
    35581 gtattagata tggatcaagc taaaccaact tcttcagaag aagaaaacag ttttggcgat
    35641 tgggatatca gacgtgaaca aaatgttcgt cctagagttg atgattccaa ttttgacaat
    35701 atcgaaaaaa aagaatttga tacattcaac cgcgaagaaa caaaatctca tggcgatgat
    35761 gaattaaata cgccaccgtt tttccgtcgt aaaaaataaa ggagaggaag agcacatgat
    35821 tgctgacaac ttgcagaaaa tcaagcaaga aattcaggat tcgtgtgctc ttgttcatcg
    35881 tgatccgaaa gaagttacat tagtagctgt aacaaaatct gttgaatccg ctcaagctga
    35941 agaattggtt agagctggcg ttatgaattg tgcagaaaac cgagtagata aattattaga
    36001 aaagaaacaa gatttatttg attttcctga aataaagtgg catttaattg gtaatttaca
    36061 gcgcagaaag gtaaaattga ttgtaaatga aattgattac tttcatgcgt tggacagttt
    36121 aagattagca gaagaaatcc agaagcggtt agagaaagaa ttatcctgtt ttattgaagt
    36181 aaatgtttct ggtgaggaat caaaacatgg aatttcacca gatgagcttt taccgtttgt
    36241 ggaatcttta gctgcctgca caaaaatcaa ggttgttggg ttgatgacta tggcgcctaa
    36301 agaagcttct gatgagcaaa tccataaagt gtttggtacg ctgaaagaat tgcgtgatct
    36361 tgttcaagca aaaggttatg cccatgcacc atgtagtgaa ttaagtatgg ggatgagtca
    36421 agactttcaa attgcgattg aagaaggtgc aacatttatc cgtgtaggaa cagcgctatt
    36481 caaagacgaa taaaggagga acaaaaatgc cgcttttaaa cagaggagca attgctaatt
    36541 ttttcggatt agctgatgag gaagagtacg aataccaaga ttatcctgaa acaacaaaaa
    36601 aggctgtaca gccaactaaa aaaaatacaa cacagaatca atcaactcat tctgtatctg
    36661 ctgcgaatac tcatgaaaaa caaaaaacgg cgacttcacg tcctgtaacg catgaaagta
    36721 ttcagccggc tgaaaagaaa aaagtaattg aactacatca atcacctaca aaaactgtag
    36781 cgaaagaaag aacagcttca agaacctcta cacaacctaa agcaaatctt gctggaaaaa
    36841 tcactgtaat ggaaccaaga gcttattctg aagctatggc gattgctaaa cgaatcattg
    36901 ctggagaagc aaccttagtg aattttcatt tagtagaaga aaaacaagcg agaagaatcg
    36961 ttgattttct aacaggaaca gtttatgcac tagatggaga tatcaaacgt gttggagatg
    37021 agatttttct ttgtacaccg actgggatgg agattgacag ttcaaccgct caatcttttg
    37081 cagatgcgaa tttgtttgat ctgtaagagg aggaactacg atttatacta ttgcactatt
    37141 acttcattta cttcaacggg cagcctattt ctatagcatt atcttgatgg tatatgcatt
    37201 gctctcttgg tttccaggcg ggtatcaatc agggctagga cgattattag ctaagatctg
    37261 cgaaccgtat atcagtttgt tcgatcgtct gcctttgagg attggaccct tggatttcac
    37321 aattttaggg gcaatcctga tcttgaactt agccgtacaa ggtttagcac agatcgttat
    37381 atggataact gtccatttag tttattgatt gaagcaacaa aatctttatt ctcagaatag
    37441 ataggagggg aaaattttgg atgcaaatgt ataccagcac tttcgggcag atgaacgtac
    37501 atttatcgat tcggtaggcg attggattga acaggttcaa ggacaatatg caccctatct
    37561 gaccgaattt cttgacccaa gacaatccta tattttagaa acactgattc gacaaagcag
    37621 tgatttgcgt ttcatgtttt atggcggata tgaacaggca gaaagaaaaa gatgtttgat
    37681 tttccccgat tattacgaac ctgtagagga agattttgaa acagcattgt atgaaatcca
    37741 ttatcctagc aaatttgcca gcctaagtca tgggaaaatc cttggaactt tagtgggaac
    37801 ggggatcaaa cgctcttact ttggcgatat catctcggac ggtgatcgct ggcaagtatt
    37861 tattgcaaat gaggtggatc attttgttgc tgcacaagta acaaagattg gaaaggttgc
    37921 tgtacgcttg gaaccaatca aatacacaga aatgattatg ccgaaagata gctggacaca
    37981 agaaagagga acagttagtt ccatgcgact agacagtgtg atctctgaga tttataatat
    38041 ttccagacag cggtccaagc agctgatcga agctggtaaa gtaaaagtga actggacaga
    38101 aaatacaaga cctgattttg tacttgaact attagatatt atttcagtca gaggttatgg
    38161 cagagtccag atccaagaac ttgaggggaa gacgaaaaaa gaaaagtaca gggtactgtt
    38221 cggtgtatta cgtaaataaa ataaaaaggt ggtttactca tggctttaac tccattagat
    38281 atccaaaata agacattccc gacaaaaatg cggggatata atcaagacga agtagatgat
    38341 ttcttagatt tagttgttcg tgactatgag gaattgactc aaagaaatcg agaattagaa
    38401 aaagcagtca aacattctga agaaaaactt gagtacttca atgaattaaa agatgctttg
    38461 aaccaatcaa tcatcgtagc tcaagatacg gctgataaag taaaaacaag tgcaagcaag
    38521 gaatccgaag tgatcgttac ttctgcacaa aacaaagcag atgagttagt tgcgaacgct
    38581 gaaaaacgtg cacatcaatt aacaactgat gcagaagaaa aagcaagaaa aatcttgaca
    38641 gatgcaacag aaaaagcaag acagcttgcg acagaaactg aagatcttaa gaaaaaaaca
    38701 cgagtattcc atcaacgtat cagcttgatg cttgagtctc aattagaaca agtgaaaagt
    38761 ccggaatggg atgaaatttt acaaccattc tccagctacg tgactgacag ccatgaagtg
    38821 atcaaagaag ttttagcaaa acagcttgac aatgaaaatg atactgatgt aaactcagac
    38881 acaggagtca tagaagcacc tatgacggca tttgatacac aggctattga tatctcgatc
    38941 gtgcctggtg aaaatgaaaa cgagtagaac agaaaagcac tttgttattc ttaaagcgag
    39001 ccgatgagag tggaagttcg gtaagacact gcatggtgaa agatcctcta cttgagacct
    39061 gcttttccga aattagagta agaagcagcg gctgacctcg ttattggtca cagagagttt
    39121 gcactagata gatgcaacta aatttgggtg gtaccacggc atgttcgtcc cttgcggctg
    39181 aacatgcttt tttgtgtccg gaaaacaaat aaaggagtgt atggttgaat gaaaatgaaa
    39241 gaaaccttgc aattaggaaa aacaaaattc cctatgcgtg gtaatttgcc aaaccgagaa
    39301 ggcgagtggc aaaaagaatg ggaagaaaat cgaatctacc aaaaaagaca agagttgaac
    39361 gaaggaaaac ctagctttgt tcttcatgat ggacctccat atgccaatgg taatatccat
    39421 ttaggacatt cattgaataa aatcagtaaa gacattatca ttcgttcaaa atcaatgtct
    39481 ggctatcgtg caccatatgt tccaggatgg gatacacatg gattgccgat tgaacaagta
    39541 ttggctaata aaggcgtgaa acgtaaagaa atgtccatgg cagaatactt ggaaaaatgt
    39601 cgtgaatatg cactttccca agtagataag caacgagcag atttcaaacg cctaggagtt
    39661 gcaggagatt gggaacatcc ttatgttaca ttagatcctt cttatgaagc tgcacaagta
    39721 cgcgtatttg gtaaaatggc tgaaaaaggc tatatttaca aaggattgaa accaatttac
    39781 tggtctccgt caagtgagtc ttctttagcg gaagctgaaa ttgaatataa agatgtaaaa
    39841 tctccatcta tttttgtagc tttcaatgtc aaagacggca aagatattct tgatgaagat
    39901 acagcttttg tcatttggac gacaacacca tggacattgc cagcaaacca aggtattgct
    39961 gtaaatccaa aatttacgta tgtattggtg gaagccgatg gccgtaagtt tgtcgtagcg
    40021 aaagatttgc tagaaacagt ccaatcagaa atcggttggg aaaatgtaac agttctaaaa
    40081 gaatttgctg gacaagaaat ggaatatatg actgcaagtc atccattcta tgaacgtgaa
    40141 tcacttgtga ttttaggcga tcatgttact ttagacgctg gtactggatt agtccatact
    40201 gctccaggac atggggaaga tgactatatc gctggtagca aatataaact atctgtagtg
    40261 tcacctgtag actcaaaagg attgtttaca gaagaagcac ctggatttga aggtatcttt
    40321 tatgacaaag caaatcctat gatcactgat ctattaaaag aaaaaggagc tttgctgaag
    40381 ctagatttct ttactcatag ttatcctcac gattggcgga cgaaaaagcc tgtgatctat
    40441 cgggcaactc cacaatggtt tgcatctatc gataaattcc gtcagaatat tttggatgaa
    40501 gtagaaaaag tagagtgggt tatcccatgg ggtaaaacac gtttgtataa tatgatccgt
    40561 gaccgcggcg attgggtaat ttcccgtcag cgtgcatggg gagtaccact tccgattttc
    40621 tatgctgaaa atggagaagc aatcatcaca ccagaaacaa tcgaacatgt ggcaaaatta
    40681 tttgctgaac atggatcaat tatctggttt gaaaaagaag cgaaagaact tcttcctgaa
    40741 ggatttaccc acccaggttc tcctaatggc gaatttacaa aagaaaaaga tatcatggat
    40801 gtctggtttg attctggttc ttctcatgaa gctgttttac gtcagcgacc agaattatca
    40861 ttcccagcag atatgtattt agaaggatca gaccaatatc gtggctggtt caactcaagt
    40921 atcacgacta gtgtggctat caatggtgta gcaccataca aatcagttat ttctcaagga
    40981 tttgctttag atggtgaagg ccgtaagatg agtaaatctt taggaaacat cattgcacca
    41041 gaaaaagtga tcaaacaatt tggtgcagat atccttcgct tatgggtatc tagtgtagat
    41101 tatgaagcag atgttcgtgt ttctatggat atcttaagtc aagtggcaga agtatatcgt
    41161 aaaatcagaa atacgatgcg tttcttatta gcgaatacag aagatttcga tcctaaaaaa
    41221 gatactgttt cgtacaatga tttacgttct gtagacaaat atatgaccgt tcgattgaac
    41281 caagtaatca aagaaatccg agaagaaggg tacgacaaat ataacttcat gcatatttac
    41341 cgtacagtta tgaacttctt gacggttgat ctatcgtcat tctacctgga ttttgctaaa
    41401 gatgtagttt atattgaagc agaagatgat tatcaacgtc gttgcatgca aactgttttc
    41461 tatcaaacag ctgtagcttt gacaaaatta ttgactccta tcattccgca tacagcagaa
    41521 gaaatctggt cattcctgaa agaagaagag gagtacgttc agttaagcga gtttcctggt
    41581 tatgaagagt ttgcaaacca agaagaattg atggatacct ggactgcttt catggacttc
    41641 cgtgataatg tcttaaaagc attggaagaa gcaagaaaca gcaaattgat tggtaaatct
    41701 ttggaagcaa aactaactgt ttatccaaaa caacaagttc gtgaaatgtt aaaagctttg
    41761 gatgcagata ttgcacaatt attgatcgtt tcaccagact actttgaagt tatggcagca
    41821 gatgaacaag tgccagataa cgctatggta tttgatgatg ttgctattac agtggaaaaa
    41881 gcagacgggg aaacttgcga tcgctgtcgc caagttcgta aagatgtagg agtagatgaa
    41941 aaacttcctc atctatgcgg tcgttgtgca aaaatcgttg aagacttcta tcctgaagct
    42001 gtagctgaag gattcgaaga aaagtaaaag ggaaaagggg gtgtgacatg ttctttgtca
    42061 cacccccttt tgttatcaat cgtttaattt tccacgttca cgataccagt tatctggttg
    42121 ccagatccat tcgaatccgt ctttttcaag tagttcgaaa gctgctttag gtcccattga
    42181 tccagctttg tagttgggaa aatccggttg tgtttggtcc caagcttttc gaatgacatc
    42241 cacgatatgc caagattgag cgacttcttc ccaatgagag aagttcgttc catcaccatt
    42301 caacgcatct aatagtaatt tttcgtaagc ttctgggcta ttttcaacca tttctgcact
    42361 atttctaaat tccaatttga ttggttccgt ttcaaatcct tgccctactt ctttcccatt
    42421 caaggataaa gaaaatcctt cagttggctg aatatagatc gttagaacat taggtggaag
    42481 tgtcgtatcg tcacatggtt catcgacaga tgttttgaat acattaacag gaacttgttt
    42541 gaatacgatg ttgatccgag tccctttttc agtcaaacgt ttgcctgtac gtacatagaa
    42601 aggaacacct gaccaacgga agttatcgat agtgaatttg cctgcgacga atgtttcagt
    42661 ctctgattga gcatccactt tgtcttcttc gcgatagccc ttgaattgta caccatccaa
    42721 ttcaccttga gcatattgcc cgcgaacgaa gttttctaac acttcttctt cgttataaat
    42781 gcggatagct ttcaatgctt tgatcttttc tgtacggatt tctttttcgg aaaatgctac
    42841 tggcggttcc attgcaagta atgctacaac ctgtaaaata tgattttgca ccatgtcttt
    42901 aagtgcgcca ctatgatcgt agtagccccc gcgatcttct acaccgaggt tttcgccaaa
    42961 agtaatttgg atattgtcga tatagcgatt gttccattga gcctcaaaaa tattattggc
    43021 aaaacggata gctgagatgt tttggatcat ttcttttcct aaataatgat caatcctgaa
    43081 aatatcttgt tctgggaata cttctctgat ttgctggttc aattcaaaag cagactggta
    43141 atcagaaccg aacggttttt ctatgatcaa acgattgaag ccattttttg tcataatatt
    43201 ttgtgatttc aaatgagaaa cgatcgttcc aaaaaattga ggtgccatag ccaaataata
    43261 gacacggtta ccgtttaatt gatagtgtcc atctaatcgg tcagacaatt cttttaatgt
    43321 ctgataatgc gttgaatcat ttacatcatg ggattgatag taaaaatggc ttgcaaaggt
    43381 agttgcttct tcatctgaag gattcaatgc acggattgtt tctttgacaa cttcacggta
    43441 gtgctcatcg ctccagggac ggcgagcggt tccgattaca gcaaaatgct cgcctaaatt
    43501 tccttttctg taaaggcgga acaaagacgg gtacaattta cgctgggcta ggtcacctgt
    43561 accgccgaat atcgtaaaca atacattttt ttcattagac atgtggatac actcctttat
    43621 attttatcga caaaaatcgt gctggccgcc ttaaagctga cggggatttt ctttctatca
    43681 ttttggatag tgatcggtcc ttcataagct gcgatgtcaa cgatctcata ttcttcgttg
    43741 atattcaggt caatagtgac taagtaatcc aacaattctt tttcatcaag cactcgtgcg
    43801 atacgcactt ttgtaccgac aggataggac tccaatgttt gtcggcgttc ttcatggaca
    43861 acttcctctt ttttaggaat cgatcctcca tgaggacaat gttcaggatg attcaaatag
    43921 ttttctaaat gatctgcaag atgttccgaa gtcacatgtt ccaatacttc agcatcatca
    43981 tggacttcat tccagctata gtctaaatgt tcaactaaaa aaacttccca taagcgatgt
    44041 ttgcgaatca gactgctagc tttttgcagt ccgcttgcag tcaattgtac accttgataa
    44101 ggggaatgtt ctacaagctc ttctttcaca agtttagaaa tcatttcact gacagatgca
    44161 gctgagacat ctagactaga tacgatttgt ttattgttga ctttcgttgt atctccactt
    44221 agttctaaaa tgattttcaa ataatcttct cgatttggtg tcatattcga tcatcctttc
    44281 atggtaaaaa accatcatta gtaagtgtaa caaaaaaaac gttaattgac tatttttcta
    44341 aataaaaaac aaaggatttt tagacgtttt tacaacaaaa aacgaaagat gatagagaag
    44401 actcattctt tcgtttataa aggatatata tatacattgg gagggatcta tttttcagat
    44461 aacaacttat atgaagtgtc tgcagattcg tcataaagag tttgttcggg ataagaaaag
    44521 ataagataaa aaccatactg atcacgtacg actaaacgat attcatctat ttctaccaca
    44581 gatgtgccaa gagactgacc gttgatcaaa aacgtgtaat cagatgtaat ctgtaattgt
    44641 tgtttttgct ggctatcact aaagaaccat gtaccttgat actttgagag tccttctgac
    44701 ttttccgctt gttttttctt tttcaagtaa ataaaacttg agagaacggt aatgagtgaa
    44761 ccaagaaaat agatcatttt ttttatcacc aaatcactcc tttatgagaa aataatcgca
    44821 tagacatatt ctttcttctt tatttcattg taccgaataa aagctaaaat ttctctaaga
    44881 ctttcgactg gtttttttac tgtttttcta caaattatga taggatacat agtaggaaga
    44941 aaggtgacat aatttgaagt atcagcaagt ggaaatagct ttttttattg accgcccgaa
    45001 tcggtttata gcacattgta tgaaaaaaga cggagaaata attattgcgc atgtcaaaaa
    45061 tacaggtaga ggaaaagagg tcctgatacc aggcgctgaa gtggctattg tatttgctcc
    45121 tggacctaaa cggaaaaccg cctatgatct gattgctgta aaaaagaagg gtgactggtt
    45181 taatatcgat agtcaattgc ctaatcggct ggcaattgat ggtattttag acggcacgat
    45241 ccttttacca ggattaactg gtccatttac ggtatacaag cgtgaagtaa cttatcttca
    45301 ctccaaattt gatatttatt tagagacggt ggtcggacaa aaagcatttg ttgaagtcaa
    45361 aggtatgaca cttgaaaata aagcgattgg tgcttttcct gatgcgccca cactcagagg
    45421 attgaaacat ataggagaat taacgtatgc cgcacaagat ggttatgccg cttatgtctt
    45481 gtttattgct cagttcgaac atcttcatct ggcaacgatc catgaagaaa tgcaaccagc
    45541 actagctgat atggttcgac atgcgcagca aagcggagtt caaatcctcg cctataattg
    45601 tcaagtatcg gcagatgagg taactgtcaa gcaggccatt ccatttgatg tagatatccc
    45661 ttttgaagat cctatacaat agaaagaagg taaaataatg atcaacttag gtattatcgg
    45721 aacaaattgg attactcatc aatttgtcca agcagcttta agcacaaaaa aatatgaatt
    45781 gacagcggta tattctagac atttggaaaa agcacaggaa tttggttctc attatgaagg
    45841 ggatatcgaa ttcgcaacag atttgaagac ttttttcaat attactcata tggacaccat
    45901 ttatattgct tctccgaata gtcttcactt tagtcaagct aagcaagcaa ttttggcagg
    45961 aaaaaatgtg atagttgaaa agccagcttt ttcgacgcca aaagaaatgg atgaaatcat
    46021 ccatttggca aatgaacaca atgtgtattt ttttgaagca gcaagaaata tccatgaatc
    46081 aggttttaaa aagattgccg attacttacc attaaaagac gagataatcg gtgcaaattt
    46141 cagctatatg aaatattctt cgcgctatga ccaagtatta gatggagaag aaccgaatat
    46201 cttctcgact catttctcag gtggtgcatt gatggattta ggtgtttacc ttgtatatgc
    46261 agctgttgct tggtttggaa tgccaaaaga agtccattat ttcccaagaa agatttctac
    46321 tggtgtagat ggtcttggat gggggatctt acgttatgag aattttgatg tatcgatcca
    46381 gccaggtaaa atcggtgatt cttatttacc gtcagagatt tattttgact caggaacgct
    46441 agtgatgaat ggagtcaatg caattgaaca agcacaattt catgatcgcg cgcataaaga
    46501 aatcattgat ttggcggtaa cagctgcaga aaatccaatg gcagatgaag cagaggattt
    46561 tgccaatgtc atggctcatc cgaaagatcc agcttgggga ttgttgtatg aagagtggat
    46621 cgagctagct agaaatgtga accaagtgat ttatgattta agaaaaaatg gcggcatcaa
    46681 attcgatgca gataatgagg aagattttta atgaacgaat ttgtacaagt atttcccgaa
    46741 aattggcaga aaaaatatga ggataaaggg tttatctcac cttctcttat tcaacgagca
    46801 gtttttcagc cactaagtaa taaacaaagt atagtagcgg tttctcctac aggttcaggt
    46861 aaaacactgg cttatctttg gcctctacta ctaaacgtgg aaccaggtga agcaagtgcg
    46921 ttggtcattt ttgcttcttc tcaagaacta gctattcaag tagcagatgt tgcacgtgaa
    46981 tggggaaaag acaaagagtt gaaagtccaa tctttggtgg gcggagccaa cgtcaaacgt
    47041 cagattgagg gtttgaagga aaaaccagaa atcttgattg gtacaccagg aagaatattg
    47101 gaattgatga aagcaaaaaa aataaaagca catcaagtga aaacaatggt atttgatgaa
    47161 gcagaccagc tatttgacgc tgggaacagc caaatcattg atcaaattct tcatcaagct
    47221 ccaacagagt atcagctagc ttttttttca gcgacagcag atcgttccct tgaaagcatt
    47281 gaaaaaatca ctgggaaaac gtttgagaca attgacgtga cagcagagga cgattctcga
    47341 aaaggactga gacattactt tttacgtgta ccgatacgaa agaaagatga ctacttgaga
    47401 cgtctcacgc atatagaaga ttttcatggt ctgattttct ttaatcaact gactgaatta
    47461 ggcgtaatgg aagaaaaatt gctgtataga ggtgtaccgg taggaagtct ggcctctgat
    47521 cagaacaagc tactccgaaa agcagcgcta gaacaattca aaaagaaaat ggtcagagca
    47581 cttttgacca cagatgtggc ggctagaggt ttagatatta caggtcttcc ttatgtagtg
    47641 aatgcagaag ttccgttaag tgaagaagct tatttgcatc gttcgggaag aactggtcga
    47701 atgggtaatg aaggaatagt aattacactc gtacaagata ataatctaag agatttaaaa
    47761 cggcttttac gtccatcaaa tataacactt gaagagattt ttttatacgg aggtaagctg
    47821 caaactgagc agccaaccaa agaagatgca gctcctgcag taaataaaaa gtatgcgaaa
    47881 actttttctg gaaaggagca gaacccagaa tataacaaag aaaaaataag aaaaaaagtt
    47941 aaaaataaat caaaaaaaga gagaaataaa ggagcaaggc gcaaataagc gcctttttat
    48001 gctatgatta tgaaaacggg aacaaaattg gttgccagag gaggggttat gtgaaagaac
    48061 gtcaagaaga gatcttgcag ctattgacag aaaaccaaca aggattgaca gcaagtgatg
    48121 tagctgagcg cttaactatc gatcgaagca atgcaagccg atatttaagt gaactataca
    48181 aggcccatca tattgtaaaa accgctggcc gaccagtcgt ttactctttg ccaacggaaa
    48241 agtcaaaatc tgatgaagtg catgtcgact cttctacgca agtgactttt gaaacactcg
    48301 ttggagaaaa tgattcttta aaagtcagca tacagcaggc aaaagctgcg attctttatc
    48361 caccgcgggg gttgcatacg attatttttg gagaaactgg tacagggaag tcgatgtttg
    48421 ctgaatgtat gtatcatttt gcaatcgatt cagagatgct ttctgcagat gcgccatttg
    48481 tttctttcaa ttgtgcggat tatgctcaaa atccgcaact gctctttgga cacatctttg
    48541 ggatcaaaaa aggggcttac acaggagcag ctcaagatag tcccggtcta atagccaaag
    48601 cagacggcgg tatattgttt ttagatgaga tccaccgttt accgccggaa gggcaggaaa
    48661 tgctgtttac tttcattgat aaaggtattt accgtccgct tggagaaagt gcacaagtac
    48721 atgaagcatc tgttcagatc attggggcga cgactgaatc ttcagaaagt ttcttatcta
    48781 cgttcaatcg acggattcct atggcaatca ccttgccgaa tcttgcttca cgttcactgg
    48841 atgagcgtta tgaaatcatc tctcttttta tcaaacaaga agcgaatcgt ttgaatcaac
    48901 gtatcgatat cgaaaaagaa gcgattcttg ccttcatgct ttatgatgcg gaaggaaata
    48961 tcggtcaagt gaaacgagac ttgaaactag tctgtgcaaa atctttttta cattaccgta
    49021 ctcatcatga gaaaaagcta atcattcgaa aagaagaact ttcccttcaa gtacaaaaag
    49081 gattactgaa aatcaaggaa ataccggaac gtctcgaccg attcatggac agcaaaagtc
    49141 agtatttgac atttgaacca ggatttgctg atgttgtctg gtcacaagat ccagaacgaa
    49201 acatgcaggt ctataacgat attgaggaaa aagtcacttc tctttccgaa accggtgtgg
    49261 agaacattga tctagagacc ctcatttcaa aagatgtgga tgcttatttc cagacatatg
    49321 tcaaagaatt gactaaaagt tcgattccca aagatctttt gccagatgaa atctggcggt
    49381 taaccaatca attgtatgat gtggctgaaa aacggttaga ccgtatttat aatgaaaaag
    49441 ctcgttttgc ttttgctttg catctgcaaa gtacattgga tcgtgtgaga gaaggtcata
    49501 tgatcgtcca cccagatttg aataacgtac ggaaaaattt taagagggaa ttccaggtag
    49561 caatcgatct ttcaacgatc attgaagaag aagaacaagt tgagattcct tttgatgaaa
    49621 tcggctttat tagtatgttt ctttctatca atctaggaga aagtgagcct gttaaagaaa
    49681 acaaagtaga tgttctcata ttgatgcacg gcagacagac tgcttcaagc atgttggaga
    49741 tggcacaaga actattagga acaaaagtag ggaaagcttt taatatgcca ctggttatgg
    49801 aagttcaaac aatgtatgaa gaagtgttac aatatgtcaa aaactatcaa gagcatttga
    49861 cgaatggcct actcttgtta acagatatgg gatcattaaa caccttcagt gatttgattt
    49921 atgaagagac tggcattcgg acgaaagcta tcacgatgac aagtaccatg attgtgatag
    49981 aagcgatacg gatggcaagt gttggaagaa gcttagaaga tatttatcaa aatatccagc
    50041 tttcctttga atcgatcgta cgtgatcagt tcaaagcgga aaagtctgaa actttacagc
    50101 gtaaaaaagc cgtaatcgtg acatgcttta ctggtgaagg agtagctgcc aaattatatc
    50161 agcgtattat gccagtgatt aatcaaaata aggtagaact gatccagatg cagtttttag
    50221 aacgtgaatc attcaaaaaa cacatcgatg ccttattgga agaatatgag atcaaagcaa
    50281 ttgcgggaac agttgatgtt gattatcaaa atatcccatt tttttcagcc tatgacgttt
    50341 ttgatgatga aaaactaaat attttaaagc gtatagctga tgatgagatc ccgacagcta
    50401 aaattgtcga ttcacttgct ggatcattaa gcgatgtctt ttctattgat gaactgatcc
    50461 gttcattgca aaagacagtt cagcagatcc agaccgattt gtcgattatc gtggaacctg
    50521 gagtagatac tggaatcgtt atccatttag ccttcatgtt agacggattg atcaaacaag
    50581 aaagccatcg gcaatttgag aaactgtcta ttttctcaaa aatttatcgt ttggaaatgg
    50641 atatcgttcg ggcaaacttg atggcactag aacgaaaata tcaggtaaaa attccagaag
    50701 atgatatcgc atttcttaca caaatgtttc ttgaaaataa aataaaaaaa tgaacacact
    50761 aatcatactg tttacacact aaacatctgt gtgcgcacta taaaaaagag ctaaaaagca
    50821 tgaaaacgct atttcagctc ttttttttat tggcatgctt cttgcgttat ataaaagtgt
    50881 aaaaaaataa aaggagtgtt aaaaatggca aaaaaaacaa tcatgttagt ttgttcagca
    50941 gggatgagta cgagtttatt ggtcacaaaa atgcaaaaag cagcagaaga aaaagggatg
    51001 gaagccgata tttttgcggt ctctgcctca gatgcagata ataatttaga atctaagaat
    51061 gtcgatgtat tattattagg tcctcaagta cgtttcatga aagctcaatt tgaacaaaaa
    51121 cttgcgccta aaggtattcc attagatgtc atcaatatgc aagactatgg catgatgaac
    51181 ggagaaaaag ttcttgcaca agcagaaaat ctaatgaaat aaatcaagta tgcagttggg
    51241 ggtataacaa cgtggaagat caacaaaatc tagaagccat catggggtta atcatgtttg
    51301 gcggtaatgc aaagagcgat gcaatggaag cgattgcggc tgctaaaatc ggtgattttg
    51361 agttagcgga taggaaaatc gctgatgcag aagaatcact tatacaagcg catcatgcac
    51421 aaacagacat gttgacacaa gaagcacaag gaaatcatat gcaagtgaca ttattgactg
    51481 ttcacagtca agatcactta atgacatcta ttgcgtttac tgatttagca aaagaaatca
    51541 tcgaacttta tcgtcgcgta tacagcgaat aaatacaact tcttttttga acggaagaag
    51601 aaaaattttt gaacggattt tttattttgt tataaggaga actctcttta tataaaaaac
    51661 ttataggagg aagtaaaaaa tgaacggact atcaagttgg atggagaaat acatcctgcc
    51721 ggttgccgca aaaatcggag cgcaaaaaca tttagttgct ttgcgtgatg cttttatcgg
    51781 catactgccc gcaacaatgg cgggatcagt cgctgtaatg atcaatgcaa ttattcgtga
    51841 tttaccgcaa cagtttaaca gtacctatgc tgacagttta gcagcagaca aaggaatctt
    51901 tgccgtattg aatgtcatca tcggaatcaa tggttttgtc tggaacggta cactagcaat
    51961 cgccggattg atctttgcct tttcttgggg gtataatctt gcccgagctt atggagtaaa
    52021 tgatctagct ggggggatcg ttggtttagc taccttgatt caaggtattt cctttggtcc
    52081 agcattatca gcagcattag atgtgaatgt tccttcaaat gtcgcagatg caatcaatag
    52141 ttctgagatt ggtgcaacga ttgcagatgg cacactgtca gttggattat ggggttggct
    52201 aaaactagat catttgaatg gaaacgctta ttttacagtt atgatcatgg gagctatttc
    52261 agtcattatt ttttgtaaat tgatgcttgc caacattacg atcaaaatgc ctgattcagt
    52321 accaccagca gtatctaaag catttgcagc cattttacca gcgacgatcg ctttatacgt
    52381 cattgctatt atcaattata tcgtaggtcg tgtagctgat gggcaactga tcattgattt
    52441 ggtgcaaaaa tatattgcag aaccattcct aggattatct caagggttgg gagcagtatt
    52501 gatcgtcaca gtatttgttc aagtattctg gttctttggt attcatggat caaatgtatt
    52561 ggcaccagtg ctagagggaa tctggggaca agcacaacta atcaatattg atattttcca
    52621 aaaaggttat aacggaaaaa ctggtacacc agccgtgtta gatgcaatcg aagatggaaa
    52681 agcttatatg tgggtccgcg gatcgttcga tgcttttgca tggtttggcg gatcaggcgg
    52741 aacgatcgtc ttactgatag ctatcttgat tttctctaaa cgtgcagatt atctaacagt
    52801 agctaaatta tccattgggc ctggtatctt caatatcaac gaaccagtga tgtttggtct
    52861 gccaatcgta ttgaatgcaa tcatgtttat cccattcttg attgctccag tagtagcaac
    52921 agcaattgga tggacagcta cttatcttgg cctagtcgct ccggtatcgc agcaagtcac
    52981 atgggtagta ccgccgttct tattgtcatt cttagcaaca ggagcggatt ggcgggcacc
    53041 gatcgtaaca ttagtatgta tggtcgtgac tttcttgatt tgggcaccat ttgtcatctc
    53101 tgcaaacaaa atggaccctg ccgcaggcga acaacaataa gatgaacgtg aggagcggga
    53161 cgctttaagt ttcgttcctc ataatgaatt ttcgaggagg aactgaaatg attacaattg
    53221 ccagtgcaat gcaacaagat gaaatcaaag aattgttaga aggatacaat gaagaaggaa
    53281 tgacttttac atttaaagaa aaacaaggaa tcaagctgtt ctttgaaaca agtgcagaag
    53341 atccggaagt tgcggctaaa aaagcaaagg aactaatcaa agcacagcct tggggaacag
    53401 tcctttattt tcaatcaaca gctgtttaga aaatggttta aaaagatagg atggttgaga
    53461 tgataaaaaa cggtttattt ttatgtagta ttggttcttt gatcgtgttg tatagtttga
    53521 atccacattc gcaaaggtat gatttgtata gtatggtcac aggtcttttt ctaacaggat
    53581 taggaatcta tttcttcatg aaggggaaaa aaagagaaga agcaaaggag aaaaataact
    53641 aatggaaatc acgaaaaaat taaatattcc agcatcgttt ttttacgata aagttatgga
    53701 ctctgtcctt ttcgatgtac gtaaagcgac cggcaaatca gtaactagaa aacagctgaa
    53761 aaatttggag tacgtcaaac aattctcgca aaataaccgg gctcgcataa aaatcgaaga
    53821 agtcattgaa aaccagtctt ataagtttcg tacatcgaca acgaagaatg aattcgtcgt
    53881 tcattatcaa atcaaaccat tggacgattc gacctgtgag gttcattaca cagaaaaaat
    53941 ggagtcttat ggcatgcttc aaaagttgaa tgatatgctt ttaggaacaa tcttgatgta
    54001 ttttaaacgg agacgtttca aaaaaatgct agatatgatc gaagcaacgt attaaatcaa
    54061 tgaaacatgg tactatttag ttattgaaaa atgaagtaag ctagaaggaa tttttcatag
    54121 gaagatagat ctttcctgcg aatcctcact agcttttttg taggaagggg cagcaaaatg
    54181 acaaacaaag taagagagct aggtgtatct tcgattgagg aaatgtttga tttagccact
    54241 tatgcattta atggggcaga tacacctgaa aggcgagaac gttttcgtac acttgcggag
    54301 aattcttgga attacggatt ttttgatgag gaggatcggc taacaagtca agtcatggcg
    54361 accccttttc cagtgaattt ttacggacaa gagtacctaa tggccggcat tggctatgtt
    54421 gcttcttatc cagaagcaag gggacaaggc gggatcaatc agatcatgga aaagatcctt
    54481 gaagattgcc gtgatcgtaa agtaagctta tcttatctgg cgccattctc ctatcccttc
    54541 tatcggcgct atggctatga acaatcattt gataaaatca gttatcaact aaacagtcgt
    54601 gatgtgccgt ttatcaaaaa aaaatctgga aaaataaagc gtatggattt tgaagatgca
    54661 aaagctgcaa tcagaagaat ttatgaacag atgccggaaa accaacgagc tggtctgaag
    54721 cgcgaagact ggtggtatac gtataaattc aagcaaaaag gcaattacca gtttgctttg
    54781 cattttgatg ataatgagga agcaacggga tatatcgttt atcagcttgc aacgtcttcc
    54841 tttattattg cggagtgggg atttttggat catgatgctt tttgcagcct tgttcgcttc
    54901 gtaagttctc acaatggtgc ttttgaaaca tttgaatatt catgcggcta cggcggtaat
    54961 gatcaaaatt atctattaga aaatccattt gcttctgtaa tgatcacacc ttatatgatg
    55021 gcgaggatcg tagatatttc tttgtttttg gaaaattatc catttaaaaa gagacaagct
    55081 gcatttgccc tacaaataga agaagatcat tatgcgaaat ggaatgaagg aatcgtggaa
    55141 gtaacaatcg aaaatggaaa aaatcatctc tcaaaagtag aacaaacaaa actcccaatc
    55201 gttcgaggaa gtatccaaca tatcacgcag ctattattag ggtatcgtaa agtggaagag
    55261 ttggtattcc aagaaagaat acaggtgaca aaagaatatg aagaaacgtt aagctcaatc
    55321 ttgccacagc aacagccaat tcttaatgac tatttttgat aaaaaacggg tgatgacaat
    55381 atttttgtca ccaccctttt gtttttcatt tggcatttga aggaaaatgt taaagtaaat
    55441 cctctttttt cgtaaatttg aattttttgt tttcttttgt tttagggttt tcttttttgt
    55501 ggtcttggat tgcttctttc gtaatctttt cccgattttt tttagatgaa tctaagcgtt
    55561 ctgcgtatac tttttctttt ggcttatcat tcattggaaa ggacctccct acattatttc
    55621 attctacctc tagtttatca tctgttaagg actagtggaa acgttttgcc taacttataa
    55681 gctgattttt ttagcagata agcttgcaag taaaaaacaa acaagctaca attgatttat
    55741 tgaaattgtt cctgtagctc agtaggatag agcaatcgcc tcctaagcga taggtcgctg
    55801 gttcaattc
//
LOCUS       DAIGWC010000009        54723 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.009, whole genome shotgun sequence.
ACCESSION   DAIGWC010000009 DAIGWC010000000
VERSION     DAIGWC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.009"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            38..997
                     /locus_tag="NOB74_000571"
     CDS             38..997
                     /locus_tag="NOB74_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1219781.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            1167..1847
                     /locus_tag="NOB74_000572"
     CDS             1167..1847
                     /locus_tag="NOB74_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI1219782.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            1937..2971
                     /locus_tag="NOB74_000573"
     CDS             1937..2971
                     /locus_tag="NOB74_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI1219783.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            2985..3320
                     /locus_tag="NOB74_000574"
     CDS             2985..3320
                     /locus_tag="NOB74_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219784.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            3304..5784
                     /locus_tag="NOB74_000575"
     CDS             3304..5784
                     /locus_tag="NOB74_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219785.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            5840..7399
                     /locus_tag="NOB74_000576"
     CDS             5840..7399
                     /locus_tag="NOB74_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1219786.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            7396..8760
                     /locus_tag="NOB74_000577"
     CDS             7396..8760
                     /locus_tag="NOB74_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI1219787.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            8931..10001
                     /locus_tag="NOB74_000578"
     CDS             8931..10001
                     /locus_tag="NOB74_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1219788.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            10016..10684
                     /locus_tag="NOB74_000579"
     CDS             10016..10684
                     /locus_tag="NOB74_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1219789.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            10704..11282
                     /locus_tag="NOB74_000580"
     CDS             10704..11282
                     /locus_tag="NOB74_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1219790.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            11683..12594
                     /locus_tag="NOB74_000581"
     CDS             11683..12594
                     /locus_tag="NOB74_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI1219791.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(12972..13889)
                     /locus_tag="NOB74_000582"
     CDS             complement(12972..13889)
                     /locus_tag="NOB74_000582"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HCI1219792.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            14091..14528
                     /gene="zapA"
                     /locus_tag="NOB74_000583"
     CDS             14091..14528
                     /gene="zapA"
                     /locus_tag="NOB74_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HCI1219793.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            14586..15134
                     /locus_tag="NOB74_000584"
     CDS             14586..15134
                     /locus_tag="NOB74_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HCI1219794.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            15249..17609
                     /locus_tag="NOB74_000585"
     CDS             15249..17609
                     /locus_tag="NOB74_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HCI1219795.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            17696..18010
                     /gene="trxA"
                     /locus_tag="NOB74_000586"
     CDS             17696..18010
                     /gene="trxA"
                     /locus_tag="NOB74_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HCI1219796.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            18192..19970
                     /gene="uvrC"
                     /locus_tag="NOB74_000587"
     CDS             18192..19970
                     /gene="uvrC"
                     /locus_tag="NOB74_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HCI1219797.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            20115..21014
                     /locus_tag="NOB74_000588"
     CDS             20115..21014
                     /locus_tag="NOB74_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1219798.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            21007..22269
                     /locus_tag="NOB74_000589"
     CDS             21007..22269
                     /locus_tag="NOB74_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1219799.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            22430..24328
                     /locus_tag="NOB74_000590"
     CDS             22430..24328
                     /locus_tag="NOB74_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HCI1219800.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(24658..25376)
                     /locus_tag="NOB74_000591"
                     /pseudo
     CDS             complement(24658..25376)
                     /locus_tag="NOB74_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
     gene            25713..26045
                     /locus_tag="NOB74_000592"
     CDS             25713..26045
                     /locus_tag="NOB74_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219801.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            26032..28035
                     /locus_tag="NOB74_000593"
     CDS             26032..28035
                     /locus_tag="NOB74_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HCI1219802.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            28054..28524
                     /locus_tag="NOB74_000594"
     CDS             28054..28524
                     /locus_tag="NOB74_000594"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HCI1219803.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            28545..29129
                     /locus_tag="NOB74_000595"
     CDS             28545..29129
                     /locus_tag="NOB74_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HCI1219804.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            29144..30130
                     /locus_tag="NOB74_000596"
     CDS             29144..30130
                     /locus_tag="NOB74_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HCI1219805.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            30120..30431
                     /locus_tag="NOB74_000597"
     CDS             30120..30431
                     /locus_tag="NOB74_000597"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HCI1219806.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            30453..32234
                     /locus_tag="NOB74_000598"
     CDS             30453..32234
                     /locus_tag="NOB74_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HCI1219807.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            32227..33603
                     /locus_tag="NOB74_000599"
     CDS             32227..33603
                     /locus_tag="NOB74_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HCI1219808.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            33610..34245
                     /locus_tag="NOB74_000600"
     CDS             33610..34245
                     /locus_tag="NOB74_000600"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HCI1219809.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            34275..35630
                     /locus_tag="NOB74_000601"
     CDS             34275..35630
                     /locus_tag="NOB74_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HCI1219810.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(35822..37216)
                     /locus_tag="NOB74_000602"
     CDS             complement(35822..37216)
                     /locus_tag="NOB74_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCI1219811.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            37308..38279
                     /locus_tag="NOB74_000603"
     CDS             37308..38279
                     /locus_tag="NOB74_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HCI1219812.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            38276..39058
                     /locus_tag="NOB74_000604"
     CDS             38276..39058
                     /locus_tag="NOB74_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HCI1219813.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(39227..39598)
                     /locus_tag="NOB74_000605"
     CDS             complement(39227..39598)
                     /locus_tag="NOB74_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI1219814.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            39732..40175
                     /locus_tag="NOB74_000606"
     CDS             39732..40175
                     /locus_tag="NOB74_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HCI1219815.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(40218..41027)
                     /gene="yidA"
                     /locus_tag="NOB74_000607"
     CDS             complement(40218..41027)
                     /gene="yidA"
                     /locus_tag="NOB74_000607"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HCI1219816.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(41046..42413)
                     /locus_tag="NOB74_000608"
     CDS             complement(41046..42413)
                     /locus_tag="NOB74_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI1219817.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(42397..43227)
                     /locus_tag="NOB74_000609"
     CDS             complement(42397..43227)
                     /locus_tag="NOB74_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HCI1219818.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            43390..43827
                     /locus_tag="NOB74_000610"
     CDS             43390..43827
                     /locus_tag="NOB74_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HCI1219819.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            43903..44523
                     /locus_tag="NOB74_000611"
     CDS             43903..44523
                     /locus_tag="NOB74_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HCI1219820.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            44712..45218
                     /locus_tag="NOB74_000612"
     CDS             44712..45218
                     /locus_tag="NOB74_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HCI1219821.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            45235..46134
                     /locus_tag="NOB74_000613"
     CDS             45235..46134
                     /locus_tag="NOB74_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HCI1219822.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            46221..47105
                     /locus_tag="NOB74_000614"
     CDS             46221..47105
                     /locus_tag="NOB74_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCI1219823.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(47297..47368)
                     /locus_tag="NOB74_000615"
     tRNA            complement(47297..47368)
                     /locus_tag="NOB74_000615"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(47333..47335),aa:Arg,seq:ccg)
     gene            47428..48762
                     /gene="rpoN"
                     /locus_tag="NOB74_000616"
     CDS             47428..48762
                     /gene="rpoN"
                     /locus_tag="NOB74_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HCI1219824.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            48911..50002
                     /locus_tag="NOB74_000617"
     CDS             48911..50002
                     /locus_tag="NOB74_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HCI1219825.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            50043..51044
                     /gene="gap"
                     /locus_tag="NOB74_000618"
     CDS             50043..51044
                     /gene="gap"
                     /locus_tag="NOB74_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCI1219826.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            51154..52344
                     /locus_tag="NOB74_000619"
     CDS             51154..52344
                     /locus_tag="NOB74_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HCI1219827.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            52448..53203
                     /locus_tag="NOB74_000620"
     CDS             52448..53203
                     /locus_tag="NOB74_000620"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCI1219828.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            53319..54617
                     /gene="eno"
                     /locus_tag="NOB74_000621"
     CDS             53319..54617
                     /gene="eno"
                     /locus_tag="NOB74_000621"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HCI1219829.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        18188 a         9538 c        11541 g        15456 t
ORIGIN      
        1 atagttccga cgaaagaatt ataaggagtg agtacaaatg acctataacc atcttacacc
       61 aactgaactc gtaatgatag aagcttattt caatcaatca caacctgttt caaaagtagc
      121 caatctgtta caacgttctc gacaaactat ttataaggtc tatcgttttc ttaaatctgg
      181 tggaagcgca atgagctact ataaacaata taagaaaaac aaacgtaact gcggaagaca
      241 tccgattgtt ttacctgatg agcaacagga atacattcaa aaaaaggttg ttcaagggtg
      301 ggctcctgat gtccttattg gtcgagcaga gtttcctatt gcttgttcgg tacgcacact
      361 gtatcgaatg tttaaagata aaacctttga cactcacgat ttaccaatga agggaaaaag
      421 aaaaccaaac ggtcataaag aaaaaagagg aaaacaaggg tttcgccggt caatccgaga
      481 cagaaagaca gactataccc agtttgatca tgaatttggt cacctggaag gtgacactat
      541 cgtgggtgga aaacataaaa gcgcggtcat cacattagtt gaacggctat ctaaagtcat
      601 cattaccttg aaacccgaag gcagacaggc taaagacatt gaaaataggc tgaatcaatg
      661 gtttcgttgt gtcccaaaaa acttatttaa atccatcaca tttgattgtg gaaaagaatt
      721 ctcaaattgg aaaaagatta gtaataccaa cgatatttca atttattttg cggatccagg
      781 aacaccttct caacgaggat tgaatgaaca ttcaaatggc ttattacgta aagatggttt
      841 gtataaagct atggatttta atggtgtatc tgaaaccttt atccaatcgg tggcatcgaa
      901 acgaaatcat attcctagaa aatcattaca ctatcggaca ccaatggaag tatttttgag
      961 ttacgtcaca aaagatgatt tgtctaactt aatttgacaa acgaaactta ataaaaaagg
     1021 aagaatattc atgtaaacga ttttattgtt tttttctctt ttatacaaaa agggtcataa
     1081 tttcaagtaa gcggatgaat tcatgaggat tttttgcata ctgtctctac tatacttagg
     1141 tcactaagaa aaaggagtga tttattatga aaaagaacat gattgggaca ttattacttt
     1201 caacacttct tctaggcggc ttggcaacac cagcttttgc tgagggtcaa gcgacttcaa
     1261 aaggagatat tacctttact gaaccaacaa ataccgtgga gcctcttaac cctactgatc
     1321 cttcaaaacc agtagagcca gcagatccgg aaaatccagc aactggccag acaggtcctt
     1381 taacactgga tgtagttccc gaattgccat ttggtacaca cgagattgaa agcggaacaa
     1441 aaacgtatca agtagacgct tcaaaaaacg atacacctta tctccaagta tcagatcgtc
     1501 gaggtgtagg tgcagatggc caagcacaag ggtggaacgt gacagtttcg gtttcagatt
     1561 ttgtaaacgg ttcacaagtt ttgcaaggcg ctgaattaga ttttggaaca tccactgtta
     1621 aaagtacgtc agataacgaa tccactggac caactagtca aactgtaact gggttgagta
     1681 aagcaagtgc agcgacacca atatttacag cagcaaaaga tcaaggtctg ggaacatggc
     1741 tttctgttta tgatccagca aatatcacac tgaaagtgcc gaaagcagca gctggaacat
     1801 tcacggctga tttgacttgg aacctcgtgg ctggcccagt agcatagagt atgaaataaa
     1861 ttcaacaaac tgcggtgaaa atactatagg tgaaggattt tttaccgcag ttgttgttga
     1921 aaggatgtgg tggacaatga atcaaagtaa acgactgttt gtttcgtttt tttctatttt
     1981 aagtctattt ttcatttttc cgtcaatcag ccaagcaaag gattcagcag gagactttgg
     2041 aatcaaaccg gtatttccag agaaccaaat agataaagca atcggttatt ttgatttatt
     2101 agtggcaccg gaacaaaatc agacactaga agtaattatc agcaattctt cagatgaaga
     2161 acgaacattt gaggtctctg tcaatccggc ggtaacgagt gatggtggaa cgatcgatta
     2221 tagtcaaaaa aacccaacgt tagatgagac attgccgttt gatgtccgtg acgttttgct
     2281 cattgcgaaa aaggaaatca atgtatcagc acatgcagaa acaactgtac ctatagaagt
     2341 gaaaatccca gcaaaaagct ttaagggacg tgtattagcg ggtattcatg tttcacctaa
     2401 agaagaagct gaaacagaaa atgctacaga aggagcacaa atcaaaaatc gtattgctta
     2461 taatctcgca gtcgttttac aagaaagtca agagacgata gaaccggatc tgaaactttt
     2521 atcaggagat ttggacgagg tcaacgcaaa gccaactgtt cagcttcgtt tccaaaatcc
     2581 tcagcctagg attatcagca atttgatatt tacgagcaag atcttttatg aaaatcagct
     2641 ttatattgaa aatacgtcta atgcattttt agttgcacca aattcgaatt ttcacttgaa
     2701 tcttgattta gctggtgata aagcaaaagc cggcgattac cgcgcagaaa tcatagcaaa
     2761 atcaggcgac agtaatgaat ggcgatttac acaaaacttt acgatcaaaa aagaaaaagc
     2821 acaaaaagta aatgaaaatt ccgtttttgc agtacaagaa caatctttcc catggcttta
     2881 tgcaggattg gttgctgcag ttctagtgtt atggttgatt ttgctgtttt tgtgggtcca
     2941 caagaaaaag aaaaaaggag aaacaacatg atgaggtgat ttcgttgaaa acatcgatct
     3001 tattgggagg gattattgca agtttgctgt tcttcagctg gcaagagcca gtccaagcag
     3061 ataccaaaag ttcaggtacg attacatttt atgatctaag tccaattccg catccaagtg
     3121 gttcagtcaa tggcgcatca aaacagcaga cacagctacc gatttataaa gaatctaatc
     3181 aacatggcgt attcccggag acgaatgaac aaaagatccg ttttctttat ttgatcattg
     3241 gtatagaatt atggcttctt gcgtggttgt tgttatggag aagaaaggaa aaggaggatg
     3301 aacatgttgc tacaaaataa attttcattt tttcgctcct tcttttttac ttcgcttttt
     3361 gttttaagta tatttatctt ttcaccttcg gcagaagctg ttggagcaac gcctcctgcc
     3421 atttcttatg atccatacac gtatgaaaat atcgtacctc caaatggtgg acgtagtgca
     3481 gtcaatggcg ggaagcttgt ccaactaact ggggctaacc aattgcctaa attgactgct
     3541 acttatttga acgatggttc aaatgatcct tggaaaggtg gcacggtccg ttttcattgg
     3601 gaaagccatg tgaaactaac aaatgtactt gatttggtga atatcactgc acaaggattt
     3661 gcatttgtgg cgatcatcaa tttgccggaa catgtatcaa gcagtgatgt attaaaagca
     3721 attgactgga acaacgccta cttgtatatt gccggtgccc ccatcaaggt tactagcgga
     3781 agtttattat cagcaggaag ccataccttg cgttttggga tggggtcgtg ggatacaaat
     3841 actctattga cagatattat tgctattatt acgcgaggcg aattcaacgt ggacgatatc
     3901 ccgcttcaat ttgatgttac agctaatgtc gcgaagatga cagaaaacgg agataaatat
     3961 gatacgagtc caaacaaaat tttgaccaag ggtaaattac aaccttctat gtctaaaaag
     4021 gccgtttttt ctgttgattt ttatgattcg aataatatta tccaagatcg tatgttcaat
     4081 tcgattttag ctccagctgc aggtagattt tatcctaaat taactggcgg aaacttgaat
     4141 ccaggagcat atgcattttc tgcaagtgca gagataaata cgtggaatag ttacatctca
     4201 ccaagtgatt caacaggaaa atataataca tttgctgata ccacagaata cgtggatgga
     4261 aataaccaga accttccagg ctctaccaat agtcggacat tgacgatggg gctgactgaa
     4321 ggacgttttg atcagttgcc atttagtcgc tttgatcgcg tagtcaacta ttttacagga
     4381 aaaaacgtta cacaaggagc aatactgact catactccag caagcacaag tggattgaat
     4441 cagacagcca atatcgtgta cagtgggaaa gatgcgcaag gcggattgct ttctcctgtt
     4501 gctttaaagg tattggagca gtacaagcta gacggaacgg ttttaccaac aaacttaaca
     4561 gccgatagtc agtggggaaa gctcctttct tctgcatcgt accaagtcac ggccaattgg
     4621 tcagcaactg aactaaaaaa gggttcgatc cattacaggc tttattcgaa aggaacccaa
     4681 aaattagcga caggatggac agatcaactt ttccaaacga tccaatcaaa taacgggggt
     4741 gtaaatacag ctacttctac actacctgca ttggcttcag ggcaatatta ttttgattat
     4801 cgcttggtgg acgatgtact tactaacatg tatccgtctt ttgcgtacaa atggcagtct
     4861 gaacaagctg gaatcaccac tcttcctcaa ataacagtgg ctaattttcc atctgtgagt
     4921 gcagatagtc agctaaaaaa ccttagcaga caacctgaga caggagatcc cctgtctgct
     4981 ctatcaggag atacgattca agaaaatgtg acattcacgt taacaaaatc tggggatgcg
     5041 ataaccgaca aaaaaatcac gatctcactt cctgaaaata ctacttatat caatggttcc
     5101 ttaaaattaa atggtacaac tatcgcagat accggcattc aacaaggagt ttctgtccca
     5161 gcagatctat tgagcaaaat aggagatacc attcatctta cttacaacta tcaattaaat
     5221 actgtagata cttctttaca atccgtcagc atactgacaa aggcagctgt actttccagc
     5281 aatattacat tagcagatgg tgctaagctt cctaacccag ttgtccaaac atctgctaaa
     5341 acaattcttg tccccaaaca agaattaaca ttagttaatg taccagatga ttttacattt
     5401 ggtaacgatc tccccaaacc gttgaagaca agttattatg aatcaaaagg cgatttttct
     5461 tttgatgtgc gggatactcg gcttccaagc acgtctcctt ggcaactgac aggtacattg
     5521 acttctttat ttaagaatga tcaaggtcaa gaattaagcg gaacaaaatt atacttcaat
     5581 cattctggat caaagcaatt gattcagcaa ggtcaaaaca cgttgattta tgagagtgat
     5641 ggaacagcta aaggagaggt tctcgttgac tttcccgata ccgatggttt actcttagag
     5701 gtaaatagca gtacgaatgc tcaacctggc gcaacgtatc aaggcatggt cacatgggaa
     5761 ctgacagctg ggccaaccag ctaagtgatt agaatttgta tggatctgtg ataactgtca
     5821 cagatcctct ttttcaagga tgagaaggaa acttctgctg ttaaaatcag aaatgcttga
     5881 aggagtggac ttggaacttt tcagtttgct tgaaaaaaat gaacaacggc aaatcaaact
     5941 tttccaactt ttattagagg aaaaaggaga ggtttccgtt aataacgtac ttacccgctt
     6001 atcagttgat cgggctacct tgaaagaaga tctgttttat ttacaagcta acttggaaaa
     6061 tatcaaacaa ttggaaattg ttatccaaga agggaatatt ttattaatca gacatggaaa
     6121 tatagcagca gtcgatgttt attatcattg ttacttgcgc tattctacaa aatatcagat
     6181 acttctttat ctgttggaaa atggctcatt tgatcggcag aaacttgtca tggaacttaa
     6241 tatcagttcg gctactttgt ctcgcagagt gaaggaatta aatgattctt taaatgagtt
     6301 tcatctgaaa ataaaaagcg ggcggctgac cggtccagaa agtcaaattc gttattttta
     6361 tttccaatta ttttggtttg gacgtcccta tcttgaaaac aaaaaagaat acagtgattt
     6421 atcaggaaac acttttttag atctgctgca aaaagagttt agttttgcta ttacagaaga
     6481 aggacgattg aaatttgaaa tatggctttc cattatgaag aagcgaatgc gctgtacgaa
     6541 aaaatccaaa ccagattata gcaatcttcc tgttggattg tttcaaacga cacaattttt
     6601 attggacctc catacatttt tgacccgtta cttctttcaa tatgcctttc cttggaatca
     6661 aaatgaaacg ttggtttttt atcttttcat gatcagtaac tttacattag atacacataa
     6721 ctcgcatgtc caggagtttt tgataagcga aaaatacaaa gacgacgtag tagctcaatt
     6781 gaatcgaacg tttaaacaat cgatagaaga atatttctct ttttatgttt ttccagaaga
     6841 gatttcgcaa aagattgcgt tgacagtgat gcaaaatcac gctcattttg cctattttag
     6901 aggatggatg aatatttttg gccaagaagg attaaaacag cggttaactg aagtagaaga
     6961 taaacaattc ctggttttat gtgaaagatt ggtcagacaa acatttgcta ttgttgattt
     7021 tactgaagta gacgaggaaa atgcccgctt tgaattattt gctcgctatg catctatttt
     7081 acggacgctg atcaagcagt tagaattacg tctgcaaatt gcttatgatc ttccttatga
     7141 aaggctaatg gcggatatcg tgaaagaaat catccaggaa caattgctga atacgatcaa
     7201 atatgattta gtcgaatacg agaaagaaaa gcagtatgat atcattttga ctagccaatt
     7261 gaaagagtac ccgtcacaga agtccgctaa agtttttgta ttcactagca acgaatataa
     7321 ttatgatttc ccctatttga accaattttt aaaagaatgt tatttagaaa aattgaattt
     7381 aaggatgaat aaaacatgaa aatcgtgatc attggtgctt cccatgaagg catcacagct
     7441 gccctaaatc taagaaaact tcaaccgaaa gcagaagttt tactgatcga tgaagatcat
     7501 aaagatggac taggctatgt ttcaaatgga atcaaccttt atttaaaagg aaagatacgt
     7561 agtttagctg aagttgccca taacatgcgg actcttcaag aaagtggggc aaaactgatc
     7621 accgaatgga gagtaactga acttgatcca gacaaacatc agctcatcct cgcatccaaa
     7681 gaaggaaaaa acgagaccat aacctatgat aaattaatcg tagcgacagg ttcctctcct
     7741 gtcaccttgt ataaacaaat tgaagctgaa aatgtctaca cctataaaaa tctagtgcaa
     7801 tctaagcaag tacttgccgc tttaaaagaa gcaaaagaag tagtgatctt cggtgctggt
     7861 tacattggat tggaattagc agatgctttg agaaataaag gatacattat tcatctagtt
     7921 gattatatgc cgaatgtttt atcaagatat ttcgataagg atatgatcaa cagttttcaa
     7981 aatcagctgc aaactaagca aataaatttt tatccaaatg aattcttgat cgattggaaa
     8041 aaatcagaag agaaagtagt atccgtacaa cttctgtctc aaacaataaa ggcagatatg
     8101 gtcatttttt ctgcccaaac tcgtcctaat acgacattgt taaaagaaaa agtggctttg
     8161 tatgaggatg agactgtgat agtcaatgaa tatctgcaga caagtgatcc ggacatctat
     8221 gcgattggag atatcgtccc agtcagtttt gacaaaaata aacggcatct ctttttacct
     8281 ttagttactc gagctgtaca tatggcaaga gcagtagcgc taactttgag tggtcagcca
     8341 accgcttacg acctcagaca aaagataaca gcagcagtca ttatagacta ctttttagga
     8401 actgtagggc tgacagaaga tgaagcgcca ttcttggaac aaaataccgg ttcgtgttca
     8461 ggagaatttg atctatttcc acaatacgac gaagaaaaca aaacagtaaa tgcaaagctg
     8521 atctaccatc cggatacatt agaaataatt ggcggacagc tgataagcca agaattctta
     8581 ttatcagatt tgaacctgct tgcggatatc gtgaaacaca aaactacgat tccacagcta
     8641 gcagttgagg attttggatt tctgtctgaa tacacctctc gttttcacta cctcaatgag
     8701 ttagctttta aagtactagc taagagagca aatagcaata gagtagataa aagactgtga
     8761 gaaatatcac ggtcttttat tgtgtgggga tataataaat attaatcaat cgagaataaa
     8821 aaattcatat aatgaaatag cggaagaatt ttttgagcat aatattcgcc aaaaatttat
     8881 caagtgataa aattgttgta taaaatgatt atttcaggag gaggagttaa atgtttttag
     8941 cattaaatga aattatgcat tcaaagttac gttatgcgtt agttgcaggg gtgatgtttt
     9001 tgatcgccta cctggtattt tttttgactg ggttagctta tggcttagct caagataatc
     9061 gaacagcagt cgacaagtgg gaggcagatt cgattgtgct ttcgaaagat gcaaattcaa
     9121 atctagggat gtccatgatt actaagaaga tagcagaaga agtcgaaggt gggaaagtgg
     9181 cgtatcttgc ccaaacacct ggagtcgtga ctagtaaaga cagtacagaa gaaggaaaaa
     9241 tcaatgttag cttcttcggt atcgataaaa atcaattcat catgcccaat cttgttgaag
     9301 gaaaagcttt tgataacgat gatgaggcag taggcgatat tagtttgaaa gaagaatatg
     9361 gtctagccat aggagataca gttaagttat ctggtagtga caagacgttt aaactaactg
     9421 gctttacgga tcatgccaaa ttcaatgtct caccagttct ctatacaacc atcaatgctt
     9481 accaagaaat ccgcttcgaa aaagaagata caagtgaaaa tgcacggatt aacgcaatag
     9541 ttgtcagagg taaaatcagt aatttacctg aagatttaga acagatcaaa atttctaaat
     9601 tcatcaatga attacctgga tataatgcgc aagtattgac ttttggattt atgatcggat
     9661 ttttgatcgt tattgcggct attgtgatcg ggattttcat ttatgtactg acgatgcaaa
     9721 agattaatat ctttggtgta atgaaagcac aagggatcac aggaggattt attgcgcgtt
     9781 ctgtagtggc acaaacattc attttatcat ttgttggtat tcttcttggt ctattaggaa
     9841 cagtgggaac atcccttgtt ctacctgatg cggttccatt ccaaagcaat tggctgtttt
     9901 ttggcgtcat tagcttgttg atgttagtag tagctgtgtt aggcgcacta ttttctgttc
     9961 ggacaatcgt aaaaatcgat ccgttgaagg caattggata agaaggagga agaacatgaa
    10021 agcaatagaa tttaaagaag tagaaaaaag tttccaagat ggcgaccaag tagttaaagc
    10081 attgaaagaa acaaccatga gtatcgataa aggggaattt gttgcaatca tcggtccttc
    10141 tggttcaggt aaaagtactt ttttgacttt ggcaggcgga ttgcagacgc ctagcagtgg
    10201 ctctgtattt atcaatgatc aagaattcag taatcaaaaa gaaagcgaac gcgttaaact
    10261 acgttttaaa gaaattggct ttattttgca agcttccaat ctggttcctt ttctgacagt
    10321 aaaaaagcag ttattattag tagataagat taaacatgaa catcgtcaaa aagaagcaaa
    10381 cgaattattt gagcagcttg gcgtggataa gttgatcaac aagtatccag aagaactatc
    10441 tggtggagaa cggcaaaggg tcgcaatcgc tcgtgcattg tacaatgatc cgtccattat
    10501 tctagcagat gaaccaactg ctagtttgga ttcagaaaag gcacgagaag tagtcgatat
    10561 cttggcaaaa gaatcaaaag acaaaaataa agcaacgatc atggttactc acgatacacg
    10621 gctgattgac aaatgcgata gaatatttat gatggaagat ggtgtattga aagaaaaaga
    10681 ataaccaaaa agcaggtgga aaaatggtcc atcgatacaa caaagataca cagcaaaaaa
    10741 ttttgaaaga agcgactgac ttgtttatgt ccaagggata tctcggcact tcaacaagag
    10801 aaatcgcaca aaaagttggg atcacccagc ccaatctcta tcattatttc ggtgataaag
    10861 aaaaactata tacggcagtt ttagaaaacc acttaaaaga tgttggaaaa gctttgagag
    10921 aaatcgttca aacaagcgaa acgggatttc aagtaacctt gacaaaaatg gcgcagtttt
    10981 tgattgagac acatctggtc gatttgtttc tgatgcttca cgatcttgaa agcaatcttt
    11041 caaaggaaac aagagatcat cttttctttc tatggaagaa aaattatcgt gaaccttttg
    11101 aagaaatctt ttcagcaaac caatctgtgc taagaaatgg gatttcaaaa gaaatcgcag
    11161 caaggcattt tttcttagtg ttagcacctt acatcactcg gtcgaaaaga cctgtggaag
    11221 aaccgctaaa tgtggcgcaa ttgatcgatt tatatttgaa tggtgtatta ggagaagcgt
    11281 aaagctgtta tatagggaga aaatagttag gtgaagaagc aagatatgac gaagatcgtt
    11341 atatcttgct tctttatata ggtagttttt cataaataca aatttgttat tctctcatga
    11401 ttatcagggt atatttttat ttattatgtc ggtgttccag gaagtgtttt aatttaataa
    11461 cgaagaaatt aattgtttgt agaatgaagg aaactattta ttgggtagat gaatcaccac
    11521 gaatagtcaa aaggagattt caggatatgc caaaaatgaa aaaaatcatt ttagcagtaa
    11581 tgttattttc tacggttata tcttttacag cccctttttt gcttacttaa gctgatttta
    11641 agttttggcc cttagtctgg atctacgagg tgagagtcaa gaatgaaaaa aataattgga
    11701 gcttttgtat ttgcaatcat tatcattatt atctgttttc aaatagatgt ttttggtcaa
    11761 aaaaagatag ttggacaaac ggtcagcagt acgaacagta cggttacaaa gacaaaggaa
    11821 tcatttgatg atacagaaca agagacatta atcaaaatcg gaaaaaatga ccgtacacta
    11881 tatacagatg actcgctaac taccccactt gcaactataa acggcggaga gctggcggag
    11941 tttctttctg aaacaaaaaa tgcttatcag atcaagacaa atgatggcta tactggatat
    12001 ttagccctcg aagatggaac caaagtcaca aagaatatac aaacaaaacc ggaagagcta
    12061 tctgatgcag tgattgtatt agatcctggg catggcggaa atgatactgg ggcattaagc
    12121 aatgatgaac aaacagaaga aaaagatata acattaagta cagccataaa agtaaaaaag
    12181 gcgctagagg atgctggagc aacggtttat ttgacccata ctacagatga attagtacag
    12241 cttggagata tatgcgacta cagtgaagaa aaaaaggcag atgtctttat cagtttacac
    12301 gcagactcta cggaatatgc gaatgaagca actggaatca cgacatatta ttactatgga
    12361 caagaggaaa cattagcaca gacaattgct gactccttca ctgatctgcc tctggattca
    12421 agaggaatct ccactgggaa ctatcaagtt cttcgagaaa atcttcaacc ttctatttta
    12481 atcgagatgg gttatatgaa taatgatagt gatttaaagg aattagtaac agacagttat
    12541 cagcagcaga ttgctgcaag tttgacacaa gcattgacca cttattttca gtaataaata
    12601 agcccagcca aacaaaaata gctcctcata tttttcgttt ggccgggctt attatcgcag
    12661 atgcaagctt ttaaacaccg tttaaggaag aggtcgtgag cctgccgttc aactctgagt
    12721 cacaaggagc aatttcaaaa aacagcttct catgtttgat gactattgtg acttgtgacc
    12781 gaggagttgg catgagaaca ccgtttaaga aaaaggttgt gaaatcaacg ttttgttctg
    12841 agtattagag aaacaaacgg aaaaatagtt cctcatattt tgccgtttgt tgagctaata
    12901 ccgaggatca gatgattgaa caccgtttat tcggaacaag ggactgtgac atgacttttg
    12961 tcacagttcc attatttttt tagtagcttc aaagcttttt ctgtattggc aaaatgaagt
    13021 ttggcatatt tttcaagcat aggcatgccg cctttctcca atagttttgc cgctacttgg
    13081 tcagatttcg ttccagctcc tgacggaagg gtgattccag cttcagctga tgctttgtct
    13141 aactcttcca aaaagctggc acgactgatg atagaagcag cagcaacagc taaatgatat
    13201 tgttctcctt tagtaacgaa gtacagtttt tcttgtaatt gatttttttc taaacgcgca
    13261 tattttttaa aatttgcttc cggcgtaaac tgatcgatca aaatcgcttc tggtttttct
    13321 ggctcgattt tttttagcag caaatggatc gcttgattgt gcaaagcgac tttcatccga
    13381 acggcattgt attttggttg gatctcattg tatttttctg gagataagac aagcagttta
    13441 taggggatgg ttttttttaa gatgtcagca agctggatga tttggctatc ttttaactct
    13501 tttgaatctc taacaccaag tttacgtaat tctgcaagct gatcacgttt cacataagca
    13561 gcacatactg ttagcggacc gaaatagctg ccatttccga cctcatcact acctaaaacg
    13621 gataattgac tgatattttt tggcaaagaa gaggctgttt ttgctggctt ggcttgttta
    13681 tcctgtgcct ccccccattt atcagcttct attgctgcat tcgtaccttg aaacatcact
    13741 tttccggatg tataagcggt aatggtcgtc ccgtcttttt ttgcagcaaa gctagtataa
    13801 ggaatctgtt tatttaacaa ataagagcga tagtatgctt tcatttgact aagttggtcg
    13861 tttgttgctt tgataatgac gttgctcata aaattctcct cgtttttata cataaaacta
    13921 taccgcaact cacgactttt cgttttctaa gagattgcga gacatagcat ttttttaaag
    13981 tttatcatat aatagttaag tatgtgaaaa atatttgtgg agaacggtga aagaaccaac
    14041 ttcatggtac actaaataaa actttcatca aataggagga aatgattcgt atggcgcacg
    14101 aaaaaacacg ctacaaagcg gtgattgcca accaaacata tactattatc ggacgggaaa
    14161 ccaagcatca tatggatatc gtaacgaagc tgatcaatga acagttagca gaattgaaac
    14221 aattatcacc acaaatggat aatgaacaag cagcaatctt gatggctgtc aatgcgcttt
    14281 cggatcaatt gaagaaacaa gaaagaatat tggagctgga agaagaaaca gcagaattaa
    14341 agaaaaaaat gatcaaattt acagagcttg aaaatcgtgt gaaacgcatt gaagcaatcg
    14401 agaacgaagc tcgggaagta ttgaaagaaa atggtcaagc agatcatacc attaaaaatc
    14461 atgtggaagc acaacagatt ttaaacgaga aacgaaaagg acaaattaaa caaaaatctt
    14521 ctaattaaga tccttttatc aaaataagaa aaatttaaaa aagttagaag agaaaggaac
    14581 gtagcatgct gagtttgctg attttatttt tattgctaat tgcgtttttt tctggagcac
    14641 gtcgcgggtt tgctttgcaa atcatattcg cgattggata tgtattgtca tttattgctg
    14701 cccagcattt ttacaaacca ttagcaagtc atttggaatt atacattcca tacccagctg
    14761 tcaccccaac atcaaagtta gcattttttg atcaggtatt tgcctttcac ctagatgaag
    14821 ctttttatgc aggaactgct tttctgatta ttttgctaat tggctggctg cttacccgat
    14881 ttgtgggggt ttttgtccat ggattgacgt atgtgccgat cttgagacag gtagactgga
    14941 ttgcaggagg catcctgtca ctaatcatgg cttacgttac tatatttttg attttgcagt
    15001 tacttgcctt tgttccatta gatgtggtcc aaaatcaatt cggcgagcat agtttcgctc
    15061 gttttatcgt tgagagaacg ccatttctta ccaacaagat gtatgagctt tgggtaacga
    15121 atattttgaa ttaaggaaaa tagtgctgga aaatatttcg ttttttgtac agagtagttt
    15181 atttaagaag gctgcgtagc gtatgtccgg cacagctctt ttttcatagt gaaagataag
    15241 gtgataaaat gaataaccga atccttgaaa cattggaatt tgaaaaagtc aaacagatgg
    15301 tcagacaatt tgtagtgact gcacaaggaa aagaagaact ggcagaattg gtaccagtga
    15361 gtgagaaaca aacgatcaca aactggcttc aagaaactga ggatggattg aaagtgcaac
    15421 gtctgcgagg cgggatccct atacctaaaa ttgaaaatat ccgtccccat atgaaacgga
    15481 ttgagatcgg agcagacttg aatggagtgg agcttgcaca agtttccaga gtattgtcta
    15541 cgacaagcga attgaatcgt ttcattgatg atctttctga cagtgaaatc gaatttgcac
    15601 gtttgtatat gtgggcagat cagttagtca cgatccctgt tttgagccgc cgtttaaagg
    15661 aagcaatcga tgaagacgga cgcgtgactg atgacgcttc tcctgagtta aagagcataa
    15721 gacagaacat tcggcgaagt gaacaagctg ttcgtgaaca gttagatggg atcgtccgtg
    15781 ggaaaaatgc aaagtattta agtgatgcga tcatcaccat gcgaaatgac cgctacgtta
    15841 tcccagtcaa acaagaatac cgcggtgtat ttggcggtgt agtccacgat caaagtgctt
    15901 caggtcagac tttatttatt gaaccaaaac aagtggtgga tttgaataat cgtttgcgtc
    15961 aataccaaat cgctgaacga aatgagattc aacgtatttt aagtgaactt tctgctgaac
    16021 ttgttcccca tcgtcaagaa atcatccaca atacttatgt gattggtaaa atggatctga
    16081 tgaatgcaaa agcacgattt ggtaaagaag taaaagccat cgtgccggga atcagtgaag
    16141 acaatcatgt cgtcttgaaa caagcaagac atccactgat cgatcaggaa aaagtagttt
    16201 ctaatgacat cacaatcgga aaagactatc aagccatcgt cattacagga cctaacacag
    16261 gtgggaaaac gatcacgttg aagactttag gtctgttaca actgatgggg caagcaggat
    16321 taccgattcc tgcaggtgaa gaaagtcaaa tcggtatttt tgaggaagta tttgcggata
    16381 taggagacga acagtcgatt gagcaaagtc tatcgacctt ttcttctcat atgacgaaca
    16441 ctgtagatat tttatcaaaa gtcaatgaaa aaagtctggt attatttgac gagctcggtg
    16501 caggaacaga tccgcaagaa ggtgctgctc tagcaatcgc aatcttagat gatcttggta
    16561 aaaagtctgc ttatgtgatg gcaacaacgc attatcctga attgaaagtt tatggatata
    16621 atcgggcaaa tacgattaat gccagcatgg agtttgatgt ggatacatta agtccaacgt
    16681 atcgtttgct gattggcgtt cctggacgaa gcaatgcgtt tgaaatctct agccgattag
    16741 gtcttgatac agaagttatt gatgaagcga agcagttgat gaatgatgag agccaagatt
    16801 taaacgaaat gatcacagat ttagagaatc gccggaaaat ggcagagacc gaatatctgg
    16861 aaatgcgtca ttttgtttct gaggcacaag aacttcacga tgatttgaaa gaagcttaca
    16921 gctatttctt tgaagaacgt gaaaaagaaa tggaaaaagc aaagaaaaaa gcaaatgaag
    16981 tcgtgtcaga ggcggaagaa aaagcagaaa aaatcattgc tgatattcgt aaaatgcaac
    17041 agcagattgg gcaaggaaat gtgaaagagc atcagttgat cgatgcaaag acccaattag
    17101 caaatctaca tcaagaagaa actttgaaga aaaataaagt attgaagaag gcgaaagaac
    17161 aaaaaacgtt gaaaccggga gacgaagtgt tggttacgac ttacggccaa agagggacgc
    17221 ttttacgtaa aaacgggaat cagtggcaag tagaaatcgg tatattaaaa atgaatgtgt
    17281 ccgaagacga gctgacgcct gttgctcctc aaaaagagcc gacacaacga gttatccatg
    17341 ctgtacgatc tgaatctagt agtcacgtgc cgaatcaatt ggaccttcga ggaaaacgat
    17401 acgaagaagc gctaagtgag gtagatcaat atttggattc tgccattcta gctggttatc
    17461 ctcaagtgac tattgtccac ggaaaaggaa caggcgcact tcgcaaggga attactgatt
    17521 atcttaaaaa ccatcggagc gtcaaaagct ttgagtttgc accggcaaac caaggcggaa
    17581 atggtgcgac aattgttaaa tttaagtaaa gcttactaaa ggtaagcaga tggttcgcta
    17641 tccaagtata gaaatgctat actagtcata gattttaaaa atggaggtct ttgatatgtc
    17701 acaagtaatt acagataaga catttaatga agaaacagat aaaggacttg tattgattga
    17761 tttttgggca acttggtgtg gtccatgtcg tatgcaagca ccgattttgg atcagttgga
    17821 acaagaatat gatgaagaag aattcagaat tgctaaaatg gatgtggatg aaaatccaga
    17881 aactcctcaa caattcggta tcatgagcat tccaacatta atgttgaaaa aagatggtca
    17941 agtagtagaa aaagctgttg gtgttcattc aaaagaacaa ctacgtcaaa tgatcgatca
    18001 atatttataa aaacttacag caaaaataag ctgagggtgg gactgaatcc agttccgtcc
    18061 tcggtttttt tgcggttgag ttaaggttat tcaaattaat attttttgag tataattacg
    18121 ttgtcaggct ggattgtttt tttgacagac atgctataat aactttaatt gaatatgaag
    18181 gggagtacca gatgaacgaa cgaatcaaaa acaaattagc tttacttcct gatcagcccg
    18241 gctgttactt gatgaaagat aaaaatggaa cgatcattta tgtcggcaaa gccaaaatat
    18301 taaaaaatcg tgtccgctca tattttactg gtagccataa tacgaaaacg gaacggcttg
    18361 ttagtgaaat cgaagacttt gaatacatcg ttacagaatc gaatatcgaa gcattgctct
    18421 tagagatcaa tctgataaag aaaaatgatc ctaaatacaa cattatgtta aaggatgata
    18481 aaacctatcc tttccttaag ataacgaatg aaaaatatcc ccgtttggtg attactcgta
    18541 aggtactaaa agacaaagca ctgtattttg gaccatatcc cgatgtcggt gcggcgaatg
    18601 agacaaagaa gatcctcgat cgattatttc ctctgagaaa atgcaaacct agtcagacga
    18661 aggagccttg tctttactat catttgggac aatgcctgtg tccttattat ttcgacgtag
    18721 atccgaaagt ctatacgaaa atcgttgatg aagtgaaaaa ctttttaaac ggaggacacg
    18781 aaaaaatcga gtcagagatc catcagaaaa tggaaaaagc tgctgaaaac atggagtttg
    18841 aaaaagctgc agaataccga gaccagatcc gtgccattga gacaatcatg actcgccaaa
    18901 aaatgacaaa tactgattta ctggatcgag atgtatttgg ttatgcgatt gataaaggat
    18961 ggatgtgtgt ccaagtgttt ttcgtaagac aaggaaagct aattgaacga gatgtttcaa
    19021 tgtttccttt ctataacgaa gcagaagaag atttcttgac ttacctcggt cagttttatc
    19081 aggaaaatga gcatttcatt cctaaagaag tcttgattcc tgatacgatc gacaagccca
    19141 gtgtagaagc tttgttagct acgaaagtgc tgcaaccaaa acgaggagaa aagaaaaaat
    19201 tagttgaatt ggcgagtaag aatgcctcag ttgctttgaa tgaacggttt gatctgattg
    19261 ccagaaaaca ggaacggacg atcggagcag ttgaacgttt aggaaacgcg atgaatatcc
    19321 cgaccccaat acgtatcgag tcttttgata actctaatat catggggacg aatcctgtgg
    19381 ctgcgatggt cgtattcatt gatggaaaac cggcaagaaa agaatatcgg aaatataaaa
    19441 taaaaacagt caacggaccg gatgattatg catcaatgag agaagtcatc tatcgcagat
    19501 attcgcgagt gattcgcgaa gggttgcctt tacctgattt gatcttgatc gatggaggaa
    19561 aaggacaagt agatgtggca aaagatgtct tagaaaatca attaggaatc gatattccta
    19621 ttgctggcat ggtaaaaaac gataaacata aaacaaatga gttgctattc ggtacagatt
    19681 tggctgtagt accgcttgag cgaaattcac cagagttttt cttactccag cgaatccaag
    19741 atgaagtcca tcgattcgca atcactttcc atcggcagct acgcagtaaa aacagttttg
    19801 cttcccgatt agatgaaatt gaagggttag gaccaaaacg aaaaaaaatg ctgcttaaag
    19861 agttcaaatc gttgaaaaat atcacagcag ccacgacaga agaattacaa gaaatcggac
    19921 tgccgaaaaa tgtcgcacaa aacgtatttg ataaattaca tcaggaatga ggaaagggca
    19981 ctttacaaag aaagtaaagt gtcctatcat tttatgtaca acaaaaagag cgtttacgtt
    20041 ttgttggtaa ataataaatc gcttacgtct ggtgtctaag gatatatgtg atttcttgaa
    20101 gaaggagtga agaaatgtta gaagtcaagg atcttgttaa aacttttggg aactacacag
    20161 ctgtcgatca tgtctctttc caaatccccg atggaaaaat catggggcta attggccaaa
    20221 acggggctgg gaagacaacg acttttcgtt tgatcttgga ttttttgaca caagaccaag
    20281 gagaagtgtt atggaatggc catcatcttg gggagaaaga ttatgatgtc atcggttatc
    20341 ttccggagga acggggactt tatccgaaag taacgattca agaccaactg ctttattttg
    20401 cagaacttag agggaaatca agaaaagaga ttgaaccaaa aatcgacttt tggatggaaa
    20461 aatttcaggt aaaagggaaa aagacggata aagtaaaatc tttgtctaaa ggaaatcagc
    20521 aaaaagtcca gctgatcgcc acgttaatcc atgaacctaa attgatcatt ttggatgagc
    20581 cattcagcgg gttagatccg gtaaatgctg aattgctaaa agatggaata ttggaattga
    20641 aaaaacatgg ttcatgtgtc attttttcta gccacaatat ggataatgta gaaaaaatct
    20701 gcgatcattt gatcatgttg cgaaacggaa aaatggtttt gaatggaaaa gtacatgaga
    20761 ttcgtgaatc atttggccgt acgaagttat tcttggaatc tggtttaagc caacaggaag
    20821 tagaagaaat cgaaggcgtg aaaaaagtga tccttcatga agacaatacg ttagagatta
    20881 ccttagaaga tcctgaagct gggaaagaaa tctttactcg tgcgactcag ttcggctaca
    20941 ttcctatgtt taaccagcaa ccgccaactt tggaagagat tttcaaattg aaagcaggtg
    21001 aaatcgatgc gtaagttttg gattattacc aaagatgtct atttaaaaaa tgttaagtcg
    21061 atttctttct tgatcatgat attagtccct tttatcatgc tgggtatcat ttatgtagca
    21121 ggaaactttg ctcaacaaaa tagtgatgtc aataaaatcg gcgtattggc tgataatgag
    21181 caaatcagtc agcaaatgag ccaagtcaaa acagatgatt ttgagttcaa agcagttgat
    21241 tctgaagaaa aagcacaaaa agagctttcg gaagaaaaaa tcgatgcgta tttagtagtc
    21301 tcaactgaga atgataagat aaatgggatg ctttatagcg aaaattcatt aggacaaagt
    21361 acacaactac tgatacaaca acaactgact ggcttgcaat cgatgcttcg agcgagtcaa
    21421 ttaggcattt caccagaaga agtagctagc ttgagccaac aagcaagttt gactcgacaa
    21481 aaagtcaatt ttgattcaaa aggaaaaatg acagtcggag aagataactc gacagtccaa
    21541 tacgtcgtaa gttatgtagc aacgattgtc ttgttcatta ttattttgac gtatgcgcag
    21601 atcattgcac aagagatcgc ttctgaaaaa ggcacgcgga tcatggaagt gatcctgtcc
    21661 agtacgactg cacaaaagca tttttacgga aaattaacag gtgttttact tgttgcatta
    21721 acgcaaatgg cattatacgg tattattttt ggtataggat acagtcaatt caaagatatg
    21781 gaaatggtca aaaatatatt agacggtatc tcattggata acttgattgg accattcttg
    21841 tggtattctc ttctattcat gatctttggc attttgattt tttctgtttt agcagcttta
    21901 tgtggctctt tggtcaacaa agcagaagat acagcaaaag caattttgcc agtgacttat
    21961 ctatctctag gcggatacat gcttggattg atactaggag cttcagatcc aaacaatatc
    22021 gttattcgga tcacttcgta tattccattc ttatcttcat atattatgcc gattcgctta
    22081 gcaaatgaga cagtcggtat gggtggagca ttgatttcct tgttggtact tgtagccgta
    22141 acattcttat tgatgatctt gtctgcaaac atgtacaaat cgaatgtact cgtttatagc
    22201 gaaggcggat tatggagttc attgaaacaa tcgatttcaa ttatgaggaa tgaacgaaaa
    22261 aaagcataaa acaatcctaa aatacagaag gaagctggac atctattgtt cccagcttct
    22321 ttttgtatag acctatttta tttattttac tatattggat atatattcat tgaaaatagt
    22381 gtataacaac tttataatat tgagtatacc aatttttgga ggcgttttaa tggaccgtta
    22441 tttagattta ctttcagaaa aattcccctc aacggaggat gtcatcacgg aaatcatcaa
    22501 tctcgaagca attttgcagc ttccaaaagg aacagagtta tttttgagtg atatacatgg
    22561 cgaatttcct gcttttgatc atattctgcg tatcggttca ggaaatctta aagaaaagat
    22621 caaagacctt ttttctgaac aaatgacgga aacggatatc agccaattca ctatttttac
    22681 ggcttatcca gaatatgcat taacgactga ttggtacaaa gaacaagata aatcgcagct
    22741 gatccatcat ttgatcgatc ttttacggtt tacgacagtc aaatataccc ggtcaaaagt
    22801 tcgaaaagga ttgccgaaag aatatagcta tatcattgag gaactcttgt atatcgatga
    22861 ccgtatcaat ggaaaaaaag actatgtaaa aaaaatcatt gaacaacttg ttttgatgaa
    22921 ggaagaagaa aaatttttaa cgaaacttgc acagacgatc caaaaatctg tcatcgatca
    22981 tttgcatatc gttggagata tttttgaccg aggaactcaa gcagccaaag tgatggatcg
    23041 aatcatggat ttttcttctg tagatatcca atggggaaat catgatattt tgtggattgg
    23101 tgcgtattgc ggctctgagg catgtttact gacactttta cggattgcag cacgctataa
    23161 ttatttattt gaattagaga aagaatatgg gttgaattta cgtccattgt tttcttttgc
    23221 tcatcaaact tatcagaaga atccagtatt tgcgcctaaa aacagtaaaa atctatccga
    23281 aagagagcaa gaagaattag aaaaaatcca tcaggcactt tctatccttc aattcaaatc
    23341 agaacatcag ttattggatc gtcgacctga atttaaaatg gacgatcgta aattgctgga
    23401 aaaaatcgac tatgaagcat caacgattga tttagaaggt cagctctatg agttgaaagg
    23461 aacttgtttt caaacgatcc agccagatga tccaaaaaaa ttcttggaag aggaacaaaa
    23521 agtgattgat agtttgatgt attcattcca gcactctttg agaatgcaaa aacatatgac
    23581 gtttttgatc gaaaaagggg gaatgtatct cacgaacaat cagcatgtgc tgtttcatgg
    23641 ctgtatacct gtagacgaga agggacagct cttagcattt gaattagacc aatcttatcg
    23701 cggaaaagaa ctgctgggct tttttgaaaa acagataact gaaagcgcaa aagatctgac
    23761 tgcaaaagaa gatttagcaa ccgatttgat ttggtatgcg tggagtgggc cattttcgcc
    23821 tttattcggc aagagtaaaa tggcgacttt tgaacgttat tttctcacag agcctcatac
    23881 gcacgtcgag aaaagcaatc cttattatca cttgcgagat gaagagtggt tcagtgaaaa
    23941 aattttagca gaattcgaca caaaagaaga agggtcagca atcattaatg ggcacacgcc
    24001 agtaaaagta aaaaaagggg agtcaccgat caaagcaaat ggaaaagtat ttgtcattga
    24061 cggaggttta tccaaagctt atcaaaaaac gacaggaatt gccggttatt cactattatg
    24121 caattcttat ggtttccaaa tcgtgacaca ttatccgttt ttgcctattg aacaacaatt
    24181 tgcaaaaaaa tccgaccaaa caaatgtgaa aaaagtaatc gaacagcaac taccacgcaa
    24241 actcaatcgt gatacaacaa aaggtatgga actgcagcag cagattaccc agctcaaaag
    24301 gctgttggac tatcgaaagg acgattgaga agaattccag tgaacattgt tccatagact
    24361 ggagactgag acaaaagtcg tgtcgcagtc tctttttccg gataaacggt gttcttctgc
    24421 caactcctcg gtcacaagtc acactattca acaaacatga aaagctgttt tttgaaattg
    24481 ctccttgtga ctcagagttg aacggcaggc tcacgacctc ttggtataaa cggtgttcaa
    24541 aagccagttt ctcggtatta agccaaattt atgcaaaaat gtgaaaagcc attttcacaa
    24601 aatttttctt aatactcgaa actaaacagc tttttcacaa ccccctcaga aagtctatta
    24661 aaattcattc acaaagaaat cgaataagcg ctgttcagat ggatgtacac ggtgggtaag
    24721 ttccggatgc cattgaacac cgaggatttt atgcatatca tctttgcttt gaaccgcttc
    24781 aacgagtcca tcgttagaaa aagcgatggc ttttaataaa ggtgaaagat ctttgactgc
    24841 ctgatgatgg taagaattca caaaatatgg atcggggaga aggttgctta acaaactgtc
    24901 tgaaacaatc ttgacttcgt gagtcgtaaa ttgcggggca gtgggctgtt gttcatgttt
    24961 tactgaccac tttggatata atgaaagatc ttgataaagt gtaccttcca aaacgacatt
    25021 caatagttgg agtccccggc agactgcaaa aattggtttt ctttgtttca atgcttccaa
    25081 gatcagtgcc tgttcaaatt ggtctcgttg aatatttgtt ccgttagctt tggatgagga
    25141 tcttccatgt aaagttgtgg actgacatct tgaccacctg caagaataag tttgtcgatt
    25201 tgtccaatca gttgaggagc tgaatctgga gacatgactg gcagaataag aggcaatcct
    25261 tgagcatcta aaactgcatc cacgaatcct tgcggtgtat agctcacttg atttccttgg
    25321 aaagtatctg ttgctcgaat cagttgattt ccggcaatgc cgatgattgg tttcatttgt
    25381 attcccccta aagtagactt attgtaacaa ggatttaaaa aaaattaaac tatgtaagac
    25441 ttgcccctat acttatctgt tcttgctgtg ttactatctg taaagagaaa tttcgtgtga
    25501 aattcatgac gatagttgaa aatattgctt aatttgttat aataaaaagt aagcagaaat
    25561 aaaaaggttg ggcgtaagct tcaaggatct agttcttcaa ggggtgagaa ggacatttta
    25621 ttgaaggggc ctgcctatac taagttatct ttagaggtac atactttcaa tgaaaaaaga
    25681 aagcatgtac ctctttttta aatcgaaagg aagtgaagca agtgttagaa gctttggaac
    25741 aaatccgaaa agcagaagaa gaaaatgaaa agcgtgctca aacactgcgg cagcagctga
    25801 agatctatgc aacagaaaaa gagcaggaat tggaaacgat ccaaacaaac tatcgacaac
    25861 aactaaaaca gttggtggaa gaaaaagaac aatttgaaat acaagaatta gaaaaagaaa
    25921 aaatgaaatt gaaagcagaa gcagacaagg tgcaagcaac tttgaaagat caatatcaaa
    25981 agcatcagag tcaagcgatc ggtgcgatca ttgaaagggt gaaagaaact tatggccgtc
    26041 actaagatgg aaaaagtgac cctcatttca gataaaagaa atcaggagag gattttacaa
    26101 gcagtacaag gaatccaaaa cgttgaaatc cgggatctgt atcaaaatag aacaaacaac
    26161 cagtgggtgg agaagtattt tccagatacc acgattattg ataaagaagc aaaattaagc
    26221 gctttaggta atcggttgaa agacatccaa gaagctatcc aattcataca acaccacggc
    26281 gatagccgtc aaaagaaact ccatttgaaa cgtcaagaac tttccttaca agatttggaa
    26341 gccaattatt ccgaagaaaa tttcataaat aaattgaaag aagtccttga tttaaaagaa
    26401 aagtgggaac aactaactga agaacgtgat cgtttagaag aagaggaaga atggcttctt
    26461 cattggcaac agctggatat tgctccaagt atgtatgcaa gtaagacgac catttttgag
    26521 atggggactg tgagtgcagc aaattttgaa agtttcaagg aagaactgag taagcttgat
    26581 gacgtttata tggaagaaat agattatacg ccaaaacaag tttatctttc gtatgttgct
    26641 ttaaaaaaat cagttgctgt tatagaagaa attgctggga aatacgggtt caataaagaa
    26701 acgtatcctt atgaacaaaa tcctaaagaa aaactgcaag agaccaagca gcaattatcc
    26761 attgttcacg agcagcaaaa gaagataacg acagcgttag gtcagtgcag tggctatatc
    26821 caagaatttg aatgggtaga agaagtcaca cttgccgttg cagaacgaga aaaaataaaa
    26881 gaacggttta tccatgcgac ttatctgatc gttttgcaag gttgggtaga tgcagaagaa
    26941 aaacagaatt tgctgcatgt gttaaacgaa accgtatcag aagaagatat atacgtcagt
    27001 ttcgaaacac caaactcaga agagattcag caggaagtcc ctactaaatt gaaaaaccat
    27061 ccgcttgtcg aaccttttga attgctgact gaaatgtaca gtctgccaaa atatgaagaa
    27121 gtagatccaa caccttggat gacaccattt tatcttgtct tcttcgggat gatggtcgca
    27181 gatgttggtt atggtttgct gatgctcatt gggacaatac tagctcaaaa actacttgtt
    27241 ctaccacgcg ggatgaaacg tttcgtaaaa ttctttgaga ttctctcgat accatcgatc
    27301 atctggggat tgatctacag ttcatttttc ggacagtcat taccaaaaga actgtttggc
    27361 atccgcttgc ctttcccaat cctatctacg acggatgacg tcaatacgat tttgatttta
    27421 tccgtgattt tcggtctgat acagattttg gttggattat ttgtggcagc aaaggaaaat
    27481 atcaggagaa aagattactt gagtgctgtc agtgatggat ttgcctggca agggatccta
    27541 attgggatcg ttattgcgtt ggttggtgcc atgttgataa aaaatacagc atttgtttac
    27601 cttggcgctg ggctatcgat cattgctgcc ttatgtatct tgatcgttcc gattatccaa
    27661 acgccgtcta aagtcaaagg tgctgccaaa ggtgcgtata atctttacgg actgaccggc
    27721 tatatcggtg atttagtcag ttatacacgt ttgatggcat tgggtatttc aggcggaagt
    27781 attggagcgg cattcaatat gctagttgct ttcatgccgc cagctgctcg attcagtgta
    27841 gggatccttt tgatcatcgc tttacacgca ctgaatatgt ttttgacact gctaagtgcc
    27901 tatgtccatg gcgcacgatt gcagtatgtc gaattttttg ggaagtttta tacaggaggc
    27961 ggacgtgcct ttgatccgct gaaaacggcg gaaaaatacg tcaacatcaa tcacaagaaa
    28021 aaaaacaata aataattgga ggatttttat ataatgatgg attacttaat tagtcaaaat
    28081 ggtggaatgg tatttgcggt attagcgatg gcaacagcga cgattttttc agggatcggt
    28141 tcagctaaag gtgttggaat gacaggtgag gcagcagcag cattgacaac aagtcaaccc
    28201 gaaaaattcg ggcaggctct gattctgcaa ttgcttccag gcacgcaagg tttgtatgga
    28261 ttcgttattg cctttttgat ttttatcaac ttaggaaatg acatgtcagt tgtacaagga
    28321 ctgaactttc taggtgcttc tctgccgatt gcttttacag gcttgttttc aggtattgcc
    28381 caaggaaaag tcgcagcggc aggtattcaa attttagcga aaaaacctga acatgctaca
    28441 aaaggaatca tttttgctgc gatggttgaa acatacgcga ttttaggttt cgttatttcc
    28501 ttcctattag tgttgaatgc ctaagcataa aggaggaaaa gcagatgaac gccattgaaa
    28561 aaatcatctc tcagatgaac gaagcagcag agcaggaaag agcggcgtta gaacaagaag
    28621 agcgaatgaa gatcgatcaa aactttgaac aaaaacgtac gcaagttgaa acagaacatc
    28681 aaaaacaaaa agaaaaacaa atcgaattac tcgaaaaaaa ataccgtcag ctaaggaatc
    28741 gccagcaagt agaagtacga caagaaaatt tgaatgcgaa gcaggaattt ttaagacgat
    28801 tgtttgcaga tgcggtaact gaaatggaaa attgggatga atctgaacaa atccagttta
    28861 tcaaaaatgc attgtattca ttacctttga caggaaaagt agcattcatt gctggagaaa
    28921 aatcagcagc ctatctttct cagacgttgt tggatgaatg gaacaatgaa cttcccttta
    28981 tgatggtttt aagtgatgaa actgttgctg atcaagcggg ttttctgata aacgatcaag
    29041 gagttcagta taattttctt ttcagcagcc ttgtacaaga tatccaagga acgatgagtt
    29101 ttgagattgc caatcaatta ttcgaataag gagggatcag tgtatggaat accacgaact
    29161 aaatcccttg attcgcggaa gagagcttga acttttgtcc aatgagacat ttgaacggat
    29221 gattcaaaca aattctgtcg aagcacttgg tgaaatattg aaatccacga tttacagtcc
    29281 atatatttat gacggatatg aatatgactt cgaacagaat cttttaaagg agcagagccg
    29341 tctatttcgc tggttaaagg aatcagcacc ggagcctgaa atcgtttgga tctatacgat
    29401 gcgttatact ttccataatc tgaaggtttt gacaaaagct gagatgacaa atcaaaatct
    29461 ggaccatttg tatatcgacg atggatttta ttcattagaa accttgaagg atgccattca
    29521 tacgcaagtt tcaaatgaac ttcctgaaag cattatggac agtatacgag aagtacgtga
    29581 ttattttgaa gagtctacca ttcttcaggg aattgacgtg atttatgatc gacagttttt
    29641 gacagagcag cgacggcttg ccgataagct aggatatcaa gaattgctga cagaagtcat
    29701 tgcttttatt gacttgacca atatcacaac gatggctcga ggaatattgc agaaaagaac
    29761 atatgggttc atgacgacgg tactttccag ctcgggaagt atcgaaaaag aagtattttt
    29821 gaactttgta gataaagata tggaagatta cacgaatttt ctattagaga cagattatgc
    29881 tgattttctg cgccctgtca tccgtgaggg aaatattgat ctcgtaaagc ttgaacagtt
    29941 gaaagatgat tatctaagtt cattgtatca agaagcacaa acccaggctt tcggaccact
    30001 gccactacta gcctttttga acgcaaaaga ggtagaaagc aaaaaccttc gtttactggt
    30061 tatcggcaaa agaagccatt tcgaatcaga aacaatcaga aagcgggtga gacaagtcta
    30121 tgacgcataa gatcggtgta gttggcgaca aagattctgt tttgccattc aaattgtttg
    30181 gctttgatgt tcgttatggt acaaccaagc aaaccgttcg tcaggcaatt gaagaaatgg
    30241 caaagaatga gtatggcgtg atttatgtca cagagcaatg tgcagcattg agcccagaaa
    30301 cgatcgaacg ttacaaggaa caaatgatac ctgctatcgt attgattccc aatcatcaag
    30361 gatcattagg gatagggctg gaagaaattc aaaaaaacgt agaaaaagca gtaggtcaaa
    30421 atatcttata gtatgaaaag gagatagaaa ttttgcaaat tggaaaaatc ataaaagtct
    30481 ccggacctct tgtaatggct gagaacatgt ctgatgccag tatccaagac atgtgtctag
    30541 tgggagatct aggagttatc ggagaaatta tcgagatgcg tggcgatgtg gcgtctattc
    30601 aagtatatga agagacttct ggaattggtc caggcgaacc ggttcgctct actggtgaag
    30661 ctttatctgt tgaattagga ccagggatca tttcacaaat gtttgacgga atccaacggc
    30721 cattagatac ctttatggaa atcacacaaa gtaatttctt agggcgcgga gttcaattgc
    30781 ccgcattgga ccatgagaaa aaatggtggt tcgaaccaac agtagaagcc ggagaaacgg
    30841 tgagtgctgg agatgttatc gggatcgtag aagaaacaaa agttataaaa cataaaatca
    30901 tggtgccaaa tgggataaaa ggaacgatca aaacaatcga aaaaggttca ttcactattg
    30961 atgaaacagt atgtgtcatt gaaaccgaaa atggtgacaa aaatttgacg atgcttcaaa
    31021 aatggccagt aagacgtagt cggccaatca aagaaaaatt aaacccggat gcacccatga
    31081 tcactggaca gcgagtgatt gatacattct tcccagtgac aaaaggagga gcagcagctg
    31141 tacctggtcc ttttggtgca gggaaaacag tcgttcagca tcaaattgca aaatgggccg
    31201 atgtggacat ggttgtctat gtgggatgtg gcgagcgtgg aaatgagatg acggatgttt
    31261 taaatgaatt ccctgaattg attgacccta atacaggaga atcgttgatg gaacgtacgg
    31321 tattgattgc taatacatca aacatgccag tagcagctcg agaagcttct atctatacgg
    31381 gaatcacaat tgcggaatat ttccgtgaca tgggttatga cgttgctatc atggcagact
    31441 ccacttcacg atgggcagaa gcacttcgtg agatgagcgg acgtttggaa gaaatgcctg
    31501 gtgatgaagg ttatccagct tatcttggtt cacggcttgc ggaatactat gaacgatctg
    31561 gaagagtcat tgcattagga tcagaaggtc gcgaaggaag tataaccgca atcagtgctg
    31621 tatccccgtc tggaggggat atttcggaac cagtcacaca aaatacattg cgggtcgtaa
    31681 aagtattctg gggtcttgat tccagtttag cccaaaaaag acattttcct tcgatcgatt
    31741 ggatacaaag ctattctctt tattcaacag aagtagggaa gtatatggat catatccttc
    31801 aagctgactg ggcatccatg gtcaccgagg gcatgcgtat tttgcaggaa gaacagcagc
    31861 tgaatgaaat cgtgcgtttg gtagggattg attccctttc agataatgac cgtctgacat
    31921 tagaagtggc aaaatccatt cgtgaagatt atttgcagca aaatgctttt gatgatgtcg
    31981 atacattcac ttcaagagag aaacaattca aaatgttgaa gatgatcttg acctttggtg
    32041 aagaaggacg ccgtgcgttg tcgttaggtg cttatttaag tgagatcatg gacggtaccg
    32101 tatcgattcg tgaaaggatc ggacgaagca aatatatccc ggaaacagaa ttagaaaaac
    32161 tagatcaaat tattggtgaa atcaagcaaa cgatgcaaac gatcgtttca gaaggaggca
    32221 tgagcaatga ttaaagaata tcgtacgatc ggtgaagtcg tcggtccatt gatggcggtt
    32281 gaaaaagttg ctggtgtcaa atatgaagaa ttaatcgaag tccgtatgca aaatggcgag
    32341 attcgtcgtg gacaagtatt ggaagtccaa gaagataaag caatggtcca aatattcgaa
    32401 ggaacaagtg gtatcaattt acgtgactct tctgtacgat ttttaggcca tcctttagaa
    32461 ctaggtgtat cggaagacat gatcggtcga gtattcgatg gtttgggacg accgaaagat
    32521 aacggaccag agatcctgcc tgaaaagcat ttggatatta acggagaagt aatcaatcca
    32581 gtagctcggg attatccaga tgagtttatc caaacaggta tctctgcaat cgatcatttg
    32641 aatacattag ttcgtgggca aaaattacca gtattttctg gctctggtct tcctcataaa
    32701 gaattagctg ctcagatcgc gcgacaagca acggtactcg attcatcaga tgatttcgcc
    32761 gtagtctttg ctgctattgg aatcactttt gaagaagctg aatttttcat ggaagatttt
    32821 cgtcaaacgg gcgcaatcga ccgttctgtc atgtttatga atttagcaaa cgaccctgca
    32881 atcgaacgta tcgctactcc tcgtatggct ttgactgctg cagaatatct tgcttatgaa
    32941 aagggaatgc atgttttggt tatcatgaca gacatgacca actatgcaga ggcattgcga
    33001 gagatttctg cagcacggcg agaagttcca ggaagaagag gatatcctgg gtatctttac
    33061 acgaacttag ctactttatt cgaacgagca ggaagaatcc gcggactaaa aggatcggtt
    33121 actcaaattc cgattctaac aatgccagaa gacgataaaa ctcatccaat ccctgacttg
    33181 actggttata ttacagaagg acagatcatc ttgactagag agctttacaa gagtgggatt
    33241 cagccaccaa ttgatgtact cccgtctctt tcgcggttaa aagataaggg aactggaccc
    33301 ggaaagacaa gagaagacca tgcagctacg atgaatcagc tttttgcagc ctatgcacaa
    33361 ggaaaacagg caaaagaatt agccgtagtt ttaggtgaat ctgctttatc tgatgtagac
    33421 aagatctatg cgaagtttgc tgagcggttt gaaaaagaat atgtcaatca aggattctac
    33481 acgaaccgtt cgattactga aacacttgat ctagggtggg aactgctatc gatgttgcca
    33541 agaaccgaat taaaacgaat caaagacgac atgctggaca aatatctgcc agaagggaag
    33601 tgagttctga tggcacgatt gaatgtgaat ccgacccgca tggaattgac tcgattgaaa
    33661 aaacagttga caactgccac aagagggcat aaattattaa aagataagca agatgaactg
    33721 atgcgtcaat tcatcctgtt gattcgaaag aacaaccagc tgcgtcaaga aatggaagag
    33781 tctatgacag aagcaatgtc tgattttgta ttggcaaatg cttcgatcac ggaacctttc
    33841 atcgaagaat tatttgtttt gccggcggaa aacgttgatt tgtctatcgt agacaaaaat
    33901 atcatgagtg taaaagtacc tgtgatgaat tttgaatatg atgaacagct gacagacaca
    33961 cctttggaat acgggtattt gaattccagt gccgaactgg atcggtcaat cgatcggttt
    34021 actaccctgc ttccaaaact tttggaactg acagaaatcg aaaaaacttg tcaactgatg
    34081 gcgagtgaaa tcgaaaagac acgtcggcga gtcaatgcat tagaatatat gacgatccct
    34141 caattagaag aaacgatcta ttatattcgt atgaagctgg aagaaaacga gcgcgcagaa
    34201 gtaacaaggt tgatcaaagt aaaaaatatg ggtaccactg actaagtggt atcttttttt
    34261 aaaagaggaa aacgatgatt aaacaaagca aacaaataaa gaaacgtttg ccggctgttc
    34321 agcttctcgc attaggattt tttctcctga ttttagttgg cggcggccta cttaccctac
    34381 cattttttag taatagtggg catgggacaa attttatcga tgcgcttttc actgcaactt
    34441 ctgctgtctg tgtaacggga ttgacaacat tgaatacagc agagcattgg aacagtgctg
    34501 gtcaattttt gatcatgctt ttgattgaga tcggcggtct tggttttatg atggttccga
    34561 ttctatgctt tgcattgata aagaagaaag tcagtctcag cacacgtatt atattaaaag
    34621 aagcgctgaa tctagaagaa gtatcaggtg tgatgaagct catgctttac atcctaaaat
    34681 tggcctttgt gatccaattg attggtacgg ttgctttatc ttttgtattt gtgcctgaat
    34741 ttggctggtt gaaaggtatc tggtacagtt tgttccatgc aatctctagt ttttgtaatg
    34801 cagggtttga tttgttagga gacagtttag ccaatcacca gcaaaatgtt tatttgatca
    34861 tggtggtatc tgctttgatc atttctggtg ggttaggctt catcgtatgg cgtgatttac
    34921 tggaatatca tcagaaaaag aagatgacga ttcattcaaa aatcgcatta accgttacag
    34981 gtaccctttt attaggcgga ttcgttgtgt tctttttcac agagcgcaat ggggcaacgc
    35041 tagtggaagg gaatatgttt caacgattgg caaacacctt ttttatgagt gtgacaccta
    35101 gaacggctgg atattattca gttgattacc tccatatgag ccatgcaggt ctgattttaa
    35161 cgatgttttt gatgtacatc ggcggaacat ctgggtcgac ggccggcgga ttgaaaacaa
    35221 ctacgttagg tgtgttgctg atccagatgc gttcgatgtt gaaaggacgt acgagagcgg
    35281 aagcatttgg ccgtaccatc cgacaaggcg cagtgttgcg ggcacttact ttattttttg
    35341 ttacgttgac gttgtgtgta gtcgccatca tgattttatc ggtgactgaa acgataccta
    35401 aaacttctgg catcgaatat attgcttttg aggtcttctc tgcgtttggt acagtaggtc
    35461 ttacgatggg attgacgcca gacttgactg caatagggaa attgatcatt atagcgctta
    35521 tgtacattgg acgagttggt gtattgactg tggtcttctc tctgatgaca aaagcacaaa
    35581 gaacacaatc aaaatacaaa tatccagaag aaagtgtcat gattggataa tttcatcttc
    35641 tgacagaaac ctagtgattt agtaaaataa gaaaataaaa taatttttct tgcttcttgg
    35701 atactttaag tgcaaaatgt tcgtttattt tttgaggcac tacccgttgt tgaacctcgg
    35761 gtagtgcctc ttttttattg aaaggaatca ataagatttg attcctttat ttatcaatag
    35821 gttataattc atattttttt attttttctt ttacgatact tagtccagaa gctaaaattt
    35881 caaggttatt agaggatagg gaaattcgaa cgaatgcatc tggttgcgca cgtgtagtaa
    35941 agcgtctgga atgataaagt cggataccgt tagcaagaaa gtcattctca attatcttag
    36001 ggtcaatctc aggatcaact ggaagaattc gatagtaagg gacacgattc gttggttttt
    36061 ctactttgaa aagagaatca aaaagctgat tggctctttt tgtaagactt aatttagttt
    36121 ctaagatcct atttgcttca tttgaatgga ggatttgagt gatgacttcc acatctaatc
    36181 cagaagtttt cacatttata ttaaaaattg cttgttctat cttgctttgg acatgtactg
    36241 gaactacaag ataagcaact cgcaatccag aacaaataaa ttttgtcatt ccagctaagt
    36301 agattgtttg gttaggtaat aaattttgga aaggaggaat gatcgtatgt tgatagtaag
    36361 ttgttaaaaa tgaatggata tcatcttcaa taacccatag accttctttt tcaatcactt
    36421 cggctaattg ctctcgtctt ttgtgagaga tttgaaaccc tataggatta ttacaagaag
    36481 gcataagaaa gacaccatga atcttctttt ttctacattc ctgaatcaat atatcaggtc
    36541 gcattccttg ctcgtcaaaa tcaattggaa cgatctctaa atgatataac tgagccaatt
    36601 caatgaaatt agcgtatgta tatcggtctg ttgctattct atcacctgga gagaaaagtg
    36661 cagaaagtgt gatagccaat ccattttgaa caccggaaac aatagataga gattctaagg
    36721 acggaatgac tccttgagtt tttaaccaat ttgctgcagt agtcaattga aaatttgtgc
    36781 ctttgggatc ttggtaatta agcaaaccaa caagatttgg gttattacta gttgattgaa
    36841 taaacgggac aacgaattta ttacattctt caaaagaact aaccagacca aaatcaatga
    36901 tatgttcggt tacttcattg gtagagatgg tgatggactc aaagacattg ggagaaataa
    36961 atgtgccact tccaatattc gtatacagca aacctttctc aattccatat ttataagcct
    37021 tgccaacggt agtaaaattt aaatctaaat aatcagctag ctctctttgg gagggtaact
    37081 gagtgttttt ctgtaattta ttctttaaaa tatcttgttc taattgttga atcaacgatc
    37141 gataataagg acgcttcaat ttttgtttgt ctggtcgcca agttaacggg taattgtcat
    37201 aagaattaat aggcattttc tccactcctt aaaattgtat accatacaat tttaccattg
    37261 attgtattga ttttagaagt taatcttttg tgaggaggga attgtctatg aaaattatta
    37321 attttgagga agtagtagct tcttttagtt ttgaagaagc gattcaagta atgaaaaaat
    37381 gtttttttga ttatgaaagt ggtaaaatca gccaaaatcc tcgattggtg gaaattttac
    37441 ctgacggaaa aggcaaaaat atgtttgcga tgatgcctgc ttatttgggg gagaacagat
    37501 attttggcac aaaagtcatt accgcttttc cggataatca tcagtatcat ttaccttctc
    37561 atttaggaga gattttcttg tttgatgctc aaaacggact acccaaagca ttgataaacg
    37621 caaatgcagt cacctggatt cgaacagctg ctgtatctgc gctggcaaca gattacttag
    37681 caaatccgca tgcagaaaca cttgctttaa ttggagctgg tcaacaagca ttgtcgcatt
    37741 tgactgcgat ttctaccatt cgtcccatca ctacagtgtt tgtttacgat attttagaag
    37801 aaagacgaaa tacttttatc gctaaagcta aaaaacagta tcctaaaata acgtttataa
    37861 atgcaatatc agtagaagat gcagtacgtc cagcggaaat catttgtacg ttgacctcta
    37921 gtaaagaggc atttcttcaa aaagagtggg taagggaaga cgcacatatc aatgctgtgg
    37981 gcacatttac tcctgataca agagagataa gtacatcgtt gatggaaact tctcaaatct
    38041 atgtagatga ttactcagct gccttaacag aaagcgggga cctgcttata gccatggcag
    38101 aaggagattt agaggaatct tgtattgttg gtacattagg cgaattagtt tctgagaaaa
    38161 aaacatttta taaaggagaa tcgaggccga cgattttcga cgcagttggt ctagctattg
    38221 aagatctttg ttgtgcagaa tatatttata acaaattaga gaaaggggct ttaaaatgaa
    38281 cttagattat tacgtagttg atgcatttgc agatgaggtg ttcaaaggaa atccagcagc
    38341 ggtttatgtg ctagaagaat ggctgccaga aggtacgatg caaaaaattg ccattgaaaa
    38401 caatttatct gaaacagcat ttacagtgaa gaaaaaccaa gaatttgagc ttagatggtt
    38461 tacgccagat cgagaaatcg atctttgtgg tcacgcgaca ttagcaacag catttgtttt
    38521 atttaactat tacaaaatac ctgatgaaac gattaaattt tctactcaaa gcggtaatct
    38581 atttgtgaca agaattaaag attattatta catggatttt cctagtatta tgccgaaaaa
    38641 agtgccgata ttgtctgaat atgaagaagc gattggggct aagattaaag aagcctactt
    38701 agcacgtgat ttatttttcg tattagaaga tgaaaaaacg gtggctaaat tgcagccaga
    38761 ttttacagct atcaaaaatt ttgaattagg aataggagtc atcgtgacag cagaaagtgt
    38821 gcaaaaagac tttgtttcta gaaccttctt tccaaaatta acaatcaatg aagatccagt
    38881 atgtggatca gcacattcta atcttattcc ttattgggca gaaagaatga ataaaacaaa
    38941 attgtcagct tatcaaatgt catcaagggg cggggatcta gaatgtgaat taaaagaaga
    39001 tcgtgtgata ataggaggaa aagcagtttt gttttctaaa ggtacctcgt ttatttgatt
    39061 tctttcaaat gaattaaaaa taaattggtg gagagtggca accttatagc tacaatggtt
    39121 gttaaaaaaa gacgcaaact ttttcaattt aatgaaaagt ttgcgtctca ttttaattat
    39181 tggtgtttgt tttttattca atcaagagta aaatgcccca tactaactat cctcggatga
    39241 cttcgatttt ataaccatca gggtcaatga caaagtagta agaaggcgca gtgccaggta
    39301 atccttttaa gtcagtaatc tcaagaccag cagctttatg ttgctcgtgt aatttttcta
    39361 gatcatcagc tgctatagcg atatgaccat agccgtctcc tagatcatac gcaccatgat
    39421 catagttgta agtcaactct aattcatagt catccccagg aagtgtcaaa taaacaagtg
    39481 taaatttgtt ttctggaaaa tcacggcggc ggctttcttc aaaaccaaat gccttttgat
    39541 aaaattcgat tgatgcttca agatctttca ctcgaacaca tgtgtgagcc attttcatag
    39601 attcatctct ccttttcctt ttactcaatc ataacaaaaa gaagtaagga aatagttgat
    39661 ttgtgcttgt tcatgagaaa tttctcatgt aaaatggata gaaaataaaa ctgttaaggt
    39721 ggaaactatt catggataaa ccaatttttg gtgaaaaaaa gcaatttgct gattatcaaa
    39781 cccgttatgc agcatatatt gtcatagaaa gagatcagca gattgcagta atcgaggctc
    39841 caaatggtgc tttttttctt cctggcgggg aaattgaagg agaagagacg aaagaagaag
    39901 cgattgtccg tgagctgata gaagaaatgg gaattgtggc agaaatttct tcttatctgg
    39961 gagaagctga tgagtatttt tactcgaatt atcgtgcaac ttattattat aatccaggat
    40021 atttctttgt tgctgattct tggaagcgta taggagaacc aactgaaaag accaataaaa
    40081 tttggtgggt gagccctcaa gaagcgcttg tgaaattgaa acgtggtagc caccgatggg
    40141 cagtcgagag atggatcgaa aaaaataaaa actgaaagaa agcgagtaga tcagctttct
    40201 ctcagttttt ttatttatta cagtacatat tttttgattg cttcagctac accgtgctcg
    40261 tcgtttgatg aagtgatgac atttgctgct tctttgacaa gagaaacggc atttcccatt
    40321 gctactccta gaccagcata ttcaatcatg gataagtcgt tctcgttatc tccgatagcc
    40381 atgatttcat cttgatcaat accaaggtgc tgtgcgagat tcgcaactgc cgcaccttta
    40441 cttgcttctt tatttagtac ttcgaagtaa tagggcgcac ttttgaccgt tgtgtattta
    40501 tcacggaaag tttgcggtaa acgcgcaatt gctgcatcta aaatttctgg ttcgtcgatc
    40561 atcatcattt tgacgatgtt catgtctggt gtcatttctt caggtgttcg atattttagc
    40621 ggcatcttga ctaaacttgc ttcgtggatc gtataagcgc tgatatctcg attaggcgtg
    40681 tagatcgctt tgtcatcgat cgaatggaga tgactgccga cacggcgtgc cattacttcg
    40741 atctctagga aatcttcatg tgtcagtccg tgacgggcga tgattttacc tgatttcgtt
    40801 tgttgtacga gtgccccgtt ataagtaata acgtaatcat tatcttgaaa aaggttcaac
    40861 tcgtttaact gttcctggac acctggtaag ggacggccag tgcataaaac gatcgaaaca
    40921 ccttttgcaa cagcagcggc aatcgcttct tttacttctt ttgttacttc tcttttctca
    40981 tttaataaag taccatcgat gtcgatagcg actagtttga tagacataat ttcctccaat
    41041 atattttaat ttatttcaat caatgcgcca ttacggatat ggctggcaaa ttcttgataa
    41101 gtttcgtcaa ataaatcata atgatcacgc aaggacggat caaccatttc ttttggaaag
    41161 aaaaatcgct catctccttg ttcttgtccc gctaatgcag caacaagctg actaacctgt
    41221 gataattcta tcaaagttcc gtcatttcgc aaaatctcga tttgtgtgcg atgtctgcct
    41281 tgttctgggc gataaaaatc ataaggtaga tcgtagctag aattcacagc agtgtaataa
    41341 acaggattat atccgacctt ttctactaac aaagtgagtt cttggactaa ttttgaatcc
    41401 cggttgccag aaaaagtagc agatttcagt ggtttacgat tcaaaaaacg tttagctaaa
    41461 tcatttaaaa taggatcagc agattcagac cattgagtaa agtaagtgcc caagacccca
    41521 tcatcaagtt tgaggtattc ttctaaagta aagcttccgt caagaaatgg cagaagtaat
    41581 tgagaatgga gttcaaaact gctggcatct tcttgataca actcgtgtgc gcgatgaagc
    41641 agatgctcca aaattacttc cataccacgg gaaacaggat ggaagtacac ttgcacatac
    41701 atttgatatc ggctaacgat ataatcttcc actgcatgca tgccactcat ggaaaaagcg
    41761 atcccgcctt cataaggacg aatcacacgt aatattcggg taagatcaaa tgttccatat
    41821 tctgttccag tgaaataagc atcccgaagc aaatagtcca ttcgatctgc atcgatctga
    41881 ctagaaatca tttggacaac ttgtgggttg gggtaagttt tttggatcac actagctacc
    41941 ttttcaggaa aaccttcttc tactcggtta agaatctgat acacttctgt ttctggagaa
    42001 gtgatgatct ctacagtgat ggcttcatga ttcgtatgga agatatgttc aaatgtatga
    42061 gagtaaggac catgaccgac atcatgcaac agtgccgcac ataaagtcac cagccgttcc
    42121 tgatcatccc agcctccgtt gcctattttt tcttttgaaa aatttcgaga aaagatatcg
    42181 cagattcgtc ttgaaatctc ataaacgcct aatgaatgag taaaacggct atgttctgct
    42241 ccgtgaaaag tgaaagaaga agtgcctaat tgtttaatgc gtcgtagacg ttggacttct
    42301 ttcgaattga tcaaatctaa gattacttga tgctggacat ggatatagtt atggactgga
    42361 tcacgaaaaa ctttttccat aggcagcatt tgatatttat aaggggttgt cataatgtag
    42421 ctcctttatg ttattacgtt gttccattct ctggatttgg ttgttccatt gctccagctg
    42481 gatttctttt tttagccagt cggtagaatc ctgtaaatca cttgcagaat acagcttttc
    42541 aaaagctttt gcaaatgctt ctttgacttc ttttacaaaa aggggttggt caagcagttc
    42601 ttcaagtgtt gccattgtag caggatccac tgcaggatag ccatttgtac caaagtcttc
    42661 ttttaaagca gattgataaa atcgcttcat gacttgccca cgtttttcct gattaccgtt
    42721 gacacttaag tacatcataa cagaaatccc atttttgatc cgacgctgag cgataccggc
    42781 aaattttttg ccatggatgc ttaaatcata agttccagga caataagaat gggtgatttc
    42841 gaatgcttgt atcggtgcct ttggaaaagc gtatttagtc aataggagca tttgctcgta
    42901 agcgtcatct atggttattt tttttgtgtc actttggggg aaaatcaaag aaatattcaa
    42961 aattccttca tctgatacga tccctaatcc acctgaattt ctgatcactg gagcgtaacc
    43021 tgcatcttcc agtgtttgga tcccgtcact tagaaaagga gttcgaacat ccttcatacc
    43081 taagatgact gtgcagtcat attgccagaa atgtaaaaag atttgctggt gttctttaga
    43141 atattccgtt aatatatctg ttaatgcaaa aggggaaaag tcgttttttt gataaatgtg
    43201 ctgatctagt cgaatcgcag ggttcattca accggctcct ttgtataaat tcatattttc
    43261 tacaatatta tactctaaaa tcaaagagtt gttttggaaa aaaggttttc tgtaaaaatg
    43321 gacaagttgg ttgacaaaac aaaagaaact aggaacaatg tagctatgag aagtaaagga
    43381 gaatgaataa tggaattatc acaaggaaca ccgatttcaa tcaaattgcg tacaaaagta
    43441 aaacagcaag gggaagtgca agatttttat tttgatttga aagggcaaat ggtgacaatt
    43501 ggcgatacgc tgtacatacg ttataaagag attcaggagg agacgggcga tgagattcct
    43561 gtaacgatca aattagttcc agatggtcat gtacagctga tccgtgcagg agaaatgcgg
    43621 atgcgtttga aatttggcta taaagaacgg ttagaaacat cctatcgaac accatacggt
    43681 atgatccaga ttgctacttt tacgaaagaa ctgcatgtta gtttgaaaga ccgtcccaca
    43741 gcagggaagg ttcgaatcga ttatgatctg ttcatgggac cggaaaaaat cggcgaatat
    43801 tatttgacct tggattttac agcgtaaata taaaagaaaa gtttgatttt ttgtgtctga
    43861 ttttgtatga taaggagtag actgtgaaag gacgtgtcct gattggaaat tagtgtattt
    43921 gaaggtgcaa acaaaagcga attatcaatg atcgaagtag cacacgcgat cttagaacaa
    43981 cgtggcgatg tcatggattt ttctgattta gctaaccaga tccaaaacta tcttgggaaa
    44041 tcagacagtg aaattcgtga ttcactcgca caattttata ctgacttgaa tattgacggc
    44101 agctttatct cattagggga taatcgttgg ggcttgcgtt catggtatgc tatcgattcg
    44161 atcgatgaag aagtaaacca tggaatggac gaagaggatg aagatactcc acgtcgccgt
    44221 aaacgcaaga aagtcaacgc ctttatcaat gatgatgaag acgcgatcga ttacaatgac
    44281 gatgacccag aagatacaga tctgacagaa gaagatgacg atgatctgtt tgatgacgat
    44341 gatgatgaag atgaagaaat cgctgcttat aattctgact tgcaagaaat cggagcagat
    44401 gacccgacag atgatgaaga agacttgcca ggaaatatcg aagaagattt aagtatcata
    44461 gacgaagacg atgatgatga agattatgaa gaggaagaat tttctgactc tgaaaaagaa
    44521 taaacattat tttcttacga gaggttgtga cagagacgat cagcctatca gaataaggag
    44581 gtgtgacacg atttttgtca caccttcttt tttgtatata aaaatcccaa gtaaatacat
    44641 aaaaaataaa aaaattgaaa cttttagcgc accttgtacg tcatattaag tgaggcagaa
    44701 aggagtggag aatgattttt actggatata agaaaaaacg gcagatcgaa aaataccgtc
    44761 acctgctgaa tggactcatc gaaactgatt atcaaaaaat gttccgtatc acgatgaatt
    44821 acgtacatga taaagaagag gccttagatg tgatgcaaga tagttttcat aaagccctga
    44881 actattttga aaaagaaaaa gagatcgagc attttagtgc atggttttat cggatattga
    44941 tccgcacggc attagatagt tggcgcagac aaaaaaggac gcctgtggac ttatttgaaa
    45001 ttcaagatat cccccaacag ttacctttag aaacttccgt tgcagagctc catatgattt
    45061 tagataaaat agacagtccg gaaaaagaga ttctgatcct ctactttttt gaaggatttc
    45121 gtttgaaaga aattgcgact atcttggata tgaatgaaaa cacagttaaa acgaaaatgt
    45181 accgctcatt gaatgcttta cgtcaaatcc tagaatgaag gagagaagag tgccatgtat
    45241 tcccaaaaag aaaatttaaa aaaactaaag aaaacttata aagaacaagc aattcccaaa
    45301 gggcttaaag aggagatccg ccagcgtttt attatcgaag agcaatcatt tataaaagca
    45361 aagcggagaa agagacgtct ccaagggttc ggagtatctt tggctatcgt aatgattaca
    45421 acaagtagcc ttctttttaa tagtcaagtt cgaagctttg cagaagattt acccatctta
    45481 ggatcagtca ttgaattgat cttaggcgaa cgctttactg atcgatctga aaaaatcgat
    45541 attcaggtac cgaagatcaa tacacaaaat gagaaagaaa ataaaacaat tcatggatta
    45601 aatcaaaaat actttcgcga aggacaagca gattttgaaa aagctgaaaa agaatatgga
    45661 aattttgaaa cggatcatta ccaagttttg ggagattatc agaaaatcgt agacgataac
    45721 cggtttctcg tgattgaaag gcagatcacc caaacagcag cagatagcca tgttgaaaaa
    45781 agatacgaca caatcgacaa gaaaaacagt gtccagctct cacttccact tttattcaaa
    45841 gatgacacct atctatctgt tttgacaaaa gaagtcaaac ggcagatggc cgaacaagtc
    45901 aaggaagatc catctaagta ctattggact gagcaagata ttcaagaagg gacgatagaa
    45961 aaaccaacac ttgttacgcc tacacgaagt ttttatttga acaaagagca tcaattagtt
    46021 ttgacttttt ctcaatacga aattgctcct ggttatatgg gtacaccaga atttgtcatt
    46081 cctaagtccg tgacaaaaac gattttggca tcggaagatt atttggatca ttagacgaga
    46141 agtagttgcg actagcagtt tcaattttca agtaagtaca agtaaataat aagaagagaa
    46201 aaagagaaag aagagatata gtgaaaagaa attatttagt tatcagtatt attgctttat
    46261 ccgtgctttt gtttttcgaa attacttcgg tggcctcctt gatcaccgaa gtaaaaggac
    46321 aaacacactc ttcggagcat tcgtcacaat ctttcaaaca atcagaacaa tcaaccatta
    46381 aaagccaatc aactgaaaca gctaacgtca aagaagccat tcaagaatca gcggaaaagg
    46441 tacaaagtca gtcatcacaa tcaacacaag acagtacaaa aacgagccga gatccggctg
    46501 tcaaaagcgt cgcaatcagc tttgatgatg gaccaggagc gaccacaaca ccgcagcttc
    46561 tgcgaatctt aaaagaaaaa aacgtgcatg ccactttttt cgtcttagga gaaaatacgg
    46621 cgcagcatcc tgaaatcgtg aagcagacag ctgaagcagg gcacgagatt ggcaatcaca
    46681 catacgatca tcagaatctg gccactcttt ctgcccagtc gatgacggag gaagtgacga
    46741 aagcagacac tgagatcaaa aaagtcactg gcaaaacccc cacttttgtt cgtccgccct
    46801 atggttctgt cacgaatgta ggagcaacga tcatccagcg accgatcatc gaatggtctg
    46861 ttgattcaga agattggaag acaagaaatc ctgatttgat tttgcagaag atccaagcaa
    46921 cagtatacga tggggcaatt attttattcc atgatatcta tcctgaaacg attcgtgccg
    46981 ttcctcaagt gatcgattat ctgaaagagc aagggtatcg catcacgaca gttggggatt
    47041 tattagggca tccaacggct gtcgagaact attatggcag aaacgatcat cggccagttc
    47101 agtaagtgag acaagtatct ttaataaata acacatttta ataagtagtt gaacacataa
    47161 ctaccttact tgcaaaggct taacaatatc tatacaggta caacaaaaaa ctgtccacca
    47221 attttctttg gcggacagtt ttcacttaaa aataaagaag caactattcg taaattatgc
    47281 taaaatagca gtagaacgcg tcctgaggga atcgaacccc cgtctcaaga accggaatct
    47341 tacgtgatat ccactacact aaggacgcaa gcactgggat aattgtaact aaacagataa
    47401 aaaattacaa ggggattgga caaaaaaatg aaatttgagc aaaatttttc acaaaaacag
    47461 cagcagacac agaaactagc catgacgcaa cagttgcaac agtccatcca agttttacaa
    47521 tataacagtg aggagctgtt ggcattcgtt gagaatcaag caatggaaaa tccattggtg
    47581 gaagttgttg agccggaatg gcagccagat tacataaaag cttcttcatc ttcttatgaa
    47641 ggagaagaga caaattacct aaatcagatt cctgatacaa aagggtcttt atttgattca
    47701 ttgatcgaac aagtccattt gaattaccga gatacttttt tgaggaaaat cgttctttat
    47761 cttgtagaat acatcgattt gaacggattt ttgacgatta gtttagaaga agccggaaaa
    47821 gagattggag ctacgcctat ccaaatgctc gatgcgttga ctctgattca gcaattagaa
    47881 ccagctggag taggtgcacg tagtttgcaa gaatgtctca tgcttcaaac agaacgagat
    47941 gattatgcgc cggaattagc ttatatcgtg ttggaagaat gttttgagga actggtggag
    48001 cgaaaatgga aagaaatcgc acaacgtttt tctgttgatc tacatgctgt tcagcagata
    48061 ttcgactatt tacaaacgtt gagtccaagc cctggccgga ttttcgaccg tagcagcgaa
    48121 ttgtacatta ttcctgatgt ccgggtatta gtggacgacg ataaaaatgt acaagttatc
    48181 tcaaaccgaa aaaatcagcc aaatatacgc tttcaagaga gttacttcaa acaaatgtca
    48241 caacaagcag ataaagaaac tgaaaattat ttaaaagaac ggaaacagga attcgaatgg
    48301 ttgaagaaaa cgatcctaca acgtggggat acaattttgc gggttgctca agtcattgtt
    48361 tcccggcaaa aagctttctt tatcgacaag gaacgtccaa tcaagcctct tacgttaaag
    48421 gaagttgcaa ctgagataga tgtgcatgaa tccacggtca gtcgtgcagt caacgggaaa
    48481 tatttggaaa cagacttcgg tgtatttgaa ttaaaaaaat ttttcactac acgaattcct
    48541 acgaatagta cagaacagac agaagacctt tcagcagata cagcgaagaa aaagctgcag
    48601 gaattagtcg atcaagaaga caaaaacaag ccgttgtctg accagaaatt ggttgaattg
    48661 ctgaaaaaag atgagatagc gatctcaaga cgaacagtag caaaatatcg tgatttatta
    48721 ggaatcccga gttcatcaaa aagaaaacgt tatgataact aatcagtcaa aagactagaa
    48781 aaagtatttc actttttcta gtctttttag ttgaaaaacg agagcaaaac tgttagactt
    48841 acagtcgtga ggttgagatt tccctttatt gatgtgaaat tcgaatagtt aatttctttt
    48901 tttatcgtat atgggtcgtt ttaagtctac attggacgta aagtgtccaa ctaaggagat
    48961 cgctatgctg gatgaaataa aaatgattga atctgttgca ccagatatta tcgaagtgtt
    49021 gcaagaacgc tataaaattt tacgaaatat ctattggatg cagccgattg gacgtcgaag
    49081 tttatcggaa agtatgggga tcacagaacg agtattgcga acagaaacag atcttttgaa
    49141 aaatctgaat ttgatcgaca cctcaaaaag cggtatgacg ctgacaacta agggcgaaga
    49201 agtttatcaa agccttgaaa acttcatgga tcagctttta ggtacgcatc aaaccgaaca
    49261 acagttggca gaatattttg gtaaccaacg ctgtatcgtt gtttcaggaa acagcgaaga
    49321 gcagaccaaa gtggctgatg cattcggcga agcgctgagc gaagccctag accgactact
    49381 tccagaaggc gagaatatca tcgctgtgat gggaggaact actatggctg tggtagccga
    49441 acaattgtct aatctggaaa ataagaaacg gcataacctg tttgtccctg caagaggcgg
    49501 gattggtgaa gcgataactg tacaggcaaa ttctgtcagt gcaagaatgg ctgctaaagc
    49561 aaacggtaac caccgtgcac tttatgttcc ggaacaatta agtctggcaa cttacaattc
    49621 tttactcaat gagccatcta tccaagaagt cttaaacttg attagtgaag cgaattgtgt
    49681 tattcatagt attgggcgtg cattacacat ggcagcacgt cgtaagatga ctgaaaaaga
    49741 attagtcatg ctgaaacaag caaatgctgt tgcggaatct tttggctact ttttcaatga
    49801 aaaaggtgaa gtcgtttata aggtccctag aatcggcata gaattgcaag atttggaaaa
    49861 agtcccgatc atcatggcaa tcgcgggcgg aaaatcaaaa gctaaagcaa ttcgagctta
    49921 tatgaaaaat gcaccaaaac aaacgtggct catcactgat gaagctgctg caaatgagat
    49981 tttaaaaggg gtaacccttt aaaataaata tttttttgat tttcataagg aggaaatctt
    50041 aaatgacagt taaagtaggt attaatggtt ttggacgtat tggacgtcta gcattccgtc
    50101 gtatccaaga tgtagatgga atcgaagtag tagcaatcaa cgacttgaca gatgctaaaa
    50161 tgttggcaca cttgttaaaa tacgacacaa ctcaaggacg tttcaacgga acagttgaag
    50221 ttcatgaagg ttcattcaac gtaaacggaa aagaagttaa agtattagct aaccgcaacc
    50281 cagaagaatt accatggggc gaactaggcg tagatatcgt tctagaatgt actggtttct
    50341 tcacttctaa atcagcagct gaaaaacatt taacagctgg tgctaaacgc gttgttatct
    50401 ctgctcctgg cggaaacgat gttccaacaa tcgtttataa cacaaaccac gaaacattaa
    50461 ctggtaaaga aacagttatc tcaggtgctt catgtactac taactgttta gctcctatgg
    50521 ctaaaacatt gaacgacaaa tttggtgttg ttgaaggatt aatgacaact atccacgctt
    50581 acacaggtga ccaaatgact ctagacggac ctcatcctaa aggtgacttc cgccgtgcac
    50641 gcgctgctgc tgcaaacatc gttcctaact caacaggtgc tgctaaagct atcggtttag
    50701 taattcctga attgaacggt aaattagacg gagctgctca acgtgttcct gtaccaacag
    50761 gttcattaac agaattagta acagttcttg aaaaagaagt aactgttgac gaaatcaatg
    50821 cagcaatgaa agaagcttca aacgaatctt acggatacaa cacagacgaa atcgtttctt
    50881 cagatatcgt tggtatgact tacggttcat tatttgatgc tacacaaact aaagtaatga
    50941 cagttggcga caaacaatta gttaaaactg ttgcttggta cgacaacgaa atgtcataca
    51001 ctgcacaatt agtacgtact ttagaatact tcgctaactt ataagataga caaacgtaca
    51061 agtgtaaatt atagacatgt acatttaaaa gcggggaagc aatcgcgctt cttccgcttt
    51121 ttttgataat aagtttattc aggaggaaat aaaatggcta agaaaacagt gaaagatatc
    51181 gatttaaaag acaaaaaagt tcttgtccgt gttgacttca acgttccttt gaaagacggc
    51241 gtgatcactg acgacactcg tatcaaagca gcattgccaa caatcaacta cgttctagaa
    51301 caaggcggaa aagcaatcct tttctctcac cttggacgtg taaaaacaga agaagataaa
    51361 gaaggaaaat ctttagctcc agttgcaaaa cgtctaggcg aattattagg taaagaagta
    51421 acattcgtac ctgaaactcg cggagaacaa ttagaagaag caatccgcaa catgaatgac
    51481 ggcgacgttg tcgtattcga aaatacacga tttgaagata ttgacggtaa aaaagaaagc
    51541 aaaaatgata cagaactagg taaatactgg gcttcattag gcgatgtatt tgttaacgat
    51601 gctttcggta cagctcaccg tgcacatgct tctaacgtag gtatcgcttc aactggtatc
    51661 ccaacagttg ctggattctt gatggaaaaa gaaatcaagt tcatcggtga agcagtagaa
    51721 gaaccaaaac gaccaatgat tgcaatcctt ggtggcgcaa aagtttctga taaaatcggc
    51781 gtaatcgaaa acttgattcc taaagcagat aaaatcttga tcggtggcgg aatgacttac
    51841 acattctacg aagcaaaagg aatcaagatc ggtaactctc tagtagaagc tgataaagtg
    51901 gaactagcaa aagaattaat cgaaaaagca ggcgacaaac ttgtcttgcc aatcgacaat
    51961 gtctgtgcac cagaattttc aaatgatgtt gaaacacaag taatcgaagg agacattcct
    52021 gatggtttga tggctttaga catcggccca gcatcagtaa aattatttgc tgatacatta
    52081 caaggtgcaa aaacagttgt ttggaacgga cctatgggtg tatttgaaat gagtaacttt
    52141 gctaaaggta caatcggtgt ttgtgaagca atcgctaact tagaaggcgc aacaacaatc
    52201 atcggtggcg gagactcagc tgcagcagca gaacaattag gatttgctga caaattcaca
    52261 cacatctcaa caggtggtgg cgcaagcttg gaattgcttg aaggtaaaga attaccagga
    52321 ctagcagcaa tcaacgataa ataaacgacc aagtttgctc aattctgacg agtaatcgat
    52381 caaaaggtga agggagtttt catgactccc tagccatttt tcaataaatt aaggagtgtg
    52441 ttcctcaatg cgtaaaccta ttatcgcagg taactggaaa atgaacaaaa ctgcatcaga
    52501 agcaaaagaa tttgctgaag cagtaaaaaa caaaatccct tcaaatgaca aagttgattc
    52561 agtcatcgga tctcctgcat tattcttaca agaattaatg acatcagctg aaggtacaga
    52621 actaaaaatc tcagcacaaa actgctactg ggaaaactca ggtgcgttca ctggtgaaac
    52681 ttcaccagca gctcttgctg atctaggtgt tcattatgtg atcatcggac attcagaacg
    52741 tcgtgaatat ttccatgaaa cagacgaaga catcaataaa aaagcaaaag ctatctttgc
    52801 aaatggtatg acaccaatcc tatgctgcgg cgaatcttta gaaacctatg aagcaggcaa
    52861 aactgctgaa tggatcgaag gacaaattac agctggttta gctgatcttt cagctgaaca
    52921 agtgtcaaac atggttattg cttatgaacc aatctgggca atcggtactg gtaaatcagc
    52981 tgacgcacaa atcgctgacg aaatttgtgg agttgtacgt caaacagttg aaaaacttta
    53041 tggaaaagaa gtatcagaag cagttcgtat ccaatacggc ggttctgtaa aaccagaaaa
    53101 tattgctgaa tacatggcaa aagaaaatgt tgacggtgct ttagtcggtg gcgcaagctt
    53161 gcaagcagat tcatttttgt cattgttaga cgctgtaaaa taattgttga aaatttgcga
    53221 aaaatgcaag aaatgtttgc actaatgagc aaaattaact aaaatcgtat atgagggaaa
    53281 tcccttagga aaaaacaaac tcaaaggaga gacaaaacat gtcaattatt actgatgttt
    53341 acgctcgcga gatcttagac tcacgtggta acccaacaat cgaagtagaa gtatacacag
    53401 aaagcggagc ttttggccgc ggaatggttc cttcaggtgc ttcaactggt gaatacgaag
    53461 cagttgaatt acgtgacgga gacaaagctc gttatggcgg taaaggtgta actaaagctg
    53521 tcgacaacgt aaacaacatc attgctgaag caatcattgg ctacgatgtt cgtgaccaaa
    53581 tggctatcga caaagctatg atcgctttag acggaactcc taacaaaggt aaattaggtg
    53641 cgaacgctat tttaggtgtt tctatcgctg ttgcacgtgc agctgctgac tacctagaag
    53701 tacctttata ccactaccta ggcggattca acacaaaagt attgccaaca ccaatgatga
    53761 acatcatcaa cggcggatca catgctgata actcaatcga cttccaagaa ttcatgatca
    53821 tgcctgttgg cgctccaaca ttcaaagaag ctctacgtat gggtgctgaa gtattccacg
    53881 cattagcttc aatcttgaaa gctcgcggat tagcaacttc tgttggtgac gaaggtggat
    53941 ttgctccaaa ccttggttca aacgaagaag gttttgaagt aatcatcgaa gcaatcgaaa
    54001 aagctggcta tgtacctggt aaagacgttg ttcttgctat ggatgctgct tcttcagaat
    54061 tctacgacaa agaaaaaggt gtttacgtac tagctgactc aggcgaaggc gaaaaaacaa
    54121 ctgacgaaat gatcaaattc tacgaagaat tagtttctaa atatccaatc atctcaatcg
    54181 aagatggatt agacgaaaac gactgggacg gattcaagaa attaactgac gtattaggcg
    54241 acaaagttca attagttggt gacgacttgt tcgtaacaaa cactcaaaaa ttatctgaag
    54301 gtatcgaaaa aggaattgct aactcaatcc ttatcaaagt gaaccaaatc ggtacattaa
    54361 cagaaacttt cgaagctatc gaaatggcta aagaagctgg ctacacagca gttgtatctc
    54421 accgttctgg tgaaacagaa gattcaacaa tctctgatat cgctgttgca acaaatgctg
    54481 gccaaatcaa aactggttct ctatcacgta ctgaccgtat tgctaaatac aaccaattac
    54541 tacgtatcga agaccaactt ggtgaagttg cagaatacaa aggtttgaaa tctttctaca
    54601 acttaaaaaa caaataattc ttttctaatg aagatacatg atcgactatt gaaagatagt
    54661 cgagtatgat cacttagtta agtaatcgaa ctctctactt gctgaaatat cagcaggtag
    54721 aga
//
LOCUS       DAIGWC010000010        50866 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.010, whole genome shotgun sequence.
ACCESSION   DAIGWC010000010 DAIGWC010000000
VERSION     DAIGWC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.010"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            558..3197
                     /locus_tag="NOB74_000622"
     CDS             558..3197
                     /locus_tag="NOB74_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI1219830.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3365..4063)
                     /locus_tag="NOB74_000623"
     CDS             complement(3365..4063)
                     /locus_tag="NOB74_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCI1219831.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4281..5426
                     /gene="tgt"
                     /locus_tag="NOB74_000624"
     CDS             4281..5426
                     /gene="tgt"
                     /locus_tag="NOB74_000624"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HCI1219832.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5523..5903
                     /gene="yajC"
                     /locus_tag="NOB74_000625"
     CDS             5523..5903
                     /gene="yajC"
                     /locus_tag="NOB74_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HCI1219833.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6208..8805
                     /gene="adhE"
                     /locus_tag="NOB74_000626"
                     /gene_synonym="adhC"
     CDS             6208..8805
                     /gene="adhE"
                     /locus_tag="NOB74_000626"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HCI1219834.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9034..10140
                     /locus_tag="NOB74_000627"
     CDS             9034..10140
                     /locus_tag="NOB74_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCI1219835.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10157..11185
                     /locus_tag="NOB74_000628"
     CDS             10157..11185
                     /locus_tag="NOB74_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HCI1219836.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11191..11670
                     /locus_tag="NOB74_000629"
     CDS             11191..11670
                     /locus_tag="NOB74_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HCI1219837.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11686..12981
                     /locus_tag="NOB74_000630"
     CDS             11686..12981
                     /locus_tag="NOB74_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HCI1219838.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            12992..13816
                     /locus_tag="NOB74_000631"
     CDS             12992..13816
                     /locus_tag="NOB74_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI1219839.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            13981..14880
                     /locus_tag="NOB74_000632"
     CDS             13981..14880
                     /locus_tag="NOB74_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1219840.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(15006..15875)
                     /locus_tag="NOB74_000633"
     CDS             complement(15006..15875)
                     /locus_tag="NOB74_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HCI1219841.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16028..17488
                     /gene="rhaB"
                     /locus_tag="NOB74_000634"
     CDS             16028..17488
                     /gene="rhaB"
                     /locus_tag="NOB74_000634"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HCI1219842.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17485..18741
                     /gene="rhaA"
                     /locus_tag="NOB74_000635"
     CDS             17485..18741
                     /gene="rhaA"
                     /locus_tag="NOB74_000635"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HCI1219843.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18755..19600
                     /gene="rhaD"
                     /locus_tag="NOB74_000636"
     CDS             18755..19600
                     /gene="rhaD"
                     /locus_tag="NOB74_000636"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HCI1219844.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19602..19913
                     /gene="rhaM"
                     /locus_tag="NOB74_000637"
     CDS             19602..19913
                     /gene="rhaM"
                     /locus_tag="NOB74_000637"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HCI1219845.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            19995..21146
                     /gene="fucO"
                     /locus_tag="NOB74_000638"
     CDS             19995..21146
                     /gene="fucO"
                     /locus_tag="NOB74_000638"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HCI1219846.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21273..22031
                     /locus_tag="NOB74_000639"
     CDS             21273..22031
                     /locus_tag="NOB74_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HCI1219847.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22131..22775
                     /locus_tag="NOB74_000640"
     CDS             22131..22775
                     /locus_tag="NOB74_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HCI1219848.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22782..23789
                     /locus_tag="NOB74_000641"
     CDS             22782..23789
                     /locus_tag="NOB74_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCI1219849.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23805..24647
                     /gene="kduI"
                     /locus_tag="NOB74_000642"
     CDS             23805..24647
                     /gene="kduI"
                     /locus_tag="NOB74_000642"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HCI1219850.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24667..25470
                     /locus_tag="NOB74_000643"
     CDS             24667..25470
                     /locus_tag="NOB74_000643"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HCI1219851.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25719..26783)
                     /locus_tag="NOB74_000644"
     CDS             complement(25719..26783)
                     /locus_tag="NOB74_000644"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HCI1219852.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26780..27865)
                     /locus_tag="NOB74_000645"
     CDS             complement(26780..27865)
                     /locus_tag="NOB74_000645"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HCI1219853.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="NOB74_000646"
     CDS             complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="NOB74_000646"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HCI1219854.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="NOB74_000647"
     CDS             complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="NOB74_000647"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HCI1219855.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            30108..30767
                     /locus_tag="NOB74_000648"
     CDS             30108..30767
                     /locus_tag="NOB74_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI1219856.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            30852..31757
                     /locus_tag="NOB74_000649"
     CDS             30852..31757
                     /locus_tag="NOB74_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI1219857.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(31759..32391)
                     /locus_tag="NOB74_000650"
     CDS             complement(31759..32391)
                     /locus_tag="NOB74_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCI1219858.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    32542..32667
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            32711..33235
                     /gene="infC"
                     /locus_tag="NOB74_000651"
     CDS             32711..33235
                     /gene="infC"
                     /locus_tag="NOB74_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HCI1219859.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            33307..33507
                     /gene="rpmI"
                     /locus_tag="NOB74_000652"
     CDS             33307..33507
                     /gene="rpmI"
                     /locus_tag="NOB74_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HCI1219860.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            33560..33919
                     /gene="rplT"
                     /locus_tag="NOB74_000653"
     CDS             33560..33919
                     /gene="rplT"
                     /locus_tag="NOB74_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HCI1219861.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            34171..35508
                     /locus_tag="NOB74_000654"
     CDS             34171..35508
                     /locus_tag="NOB74_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HCI1219862.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            35556..37685
                     /locus_tag="NOB74_000655"
     CDS             35556..37685
                     /locus_tag="NOB74_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HCI1219863.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            37660..38349
                     /locus_tag="NOB74_000656"
     CDS             37660..38349
                     /locus_tag="NOB74_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219864.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(38757..39370)
                     /locus_tag="NOB74_000657"
                     /pseudo
     CDS             complement(38757..39370)
                     /locus_tag="NOB74_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(39506..39673)
                     /locus_tag="NOB74_000658"
     CDS             complement(39506..39673)
                     /locus_tag="NOB74_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219865.1"
                     /translation="MYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKESEAFAKRIGG
                     RVKPIQEVRPD"
     gene            complement(39750..40190)
                     /locus_tag="NOB74_000659"
     CDS             complement(39750..40190)
                     /locus_tag="NOB74_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HCI1219866.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(40194..41039)
                     /locus_tag="NOB74_000660"
     CDS             complement(40194..41039)
                     /locus_tag="NOB74_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HCI1219867.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            41188..42606
                     /gene="pepV"
                     /locus_tag="NOB74_000661"
     CDS             41188..42606
                     /gene="pepV"
                     /locus_tag="NOB74_000661"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HCI1219868.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(42663..43610)
                     /locus_tag="NOB74_000662"
     CDS             complement(42663..43610)
                     /locus_tag="NOB74_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI1219869.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(43833..44183)
                     /locus_tag="NOB74_000663"
     CDS             complement(43833..44183)
                     /locus_tag="NOB74_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCI1219870.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            44383..45462
                     /gene="pepA"
                     /locus_tag="NOB74_000664"
     CDS             44383..45462
                     /gene="pepA"
                     /locus_tag="NOB74_000664"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HCI1219871.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            45606..45926
                     /locus_tag="NOB74_000665"
     CDS             45606..45926
                     /locus_tag="NOB74_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCI1219872.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            45948..46412
                     /locus_tag="NOB74_000666"
     CDS             45948..46412
                     /locus_tag="NOB74_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI1219873.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            46617..47222
                     /locus_tag="NOB74_000667"
     CDS             46617..47222
                     /locus_tag="NOB74_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HCI1219874.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(47261..48550)
                     /locus_tag="NOB74_000668"
     CDS             complement(47261..48550)
                     /locus_tag="NOB74_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HCI1219875.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            48978..49457
                     /gene="rlmH"
                     /locus_tag="NOB74_000669"
     CDS             48978..49457
                     /gene="rlmH"
                     /locus_tag="NOB74_000669"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HCI1219876.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            49542..50051
                     /locus_tag="NOB74_000670"
     CDS             49542..50051
                     /locus_tag="NOB74_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HCI1219877.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            50151..50801
                     /locus_tag="NOB74_000671"
     CDS             50151..50801
                     /locus_tag="NOB74_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219878.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
BASE COUNT        16186 a         9206 c        10918 g        14556 t
ORIGIN      
        1 aaaaagccga gctctcgata agctcggctt tcttgtacct cggaaggatt caaataaaca
       61 gaaatgattg taactttcca tcatacatgc aaagcacggt gttgaatttc ttcatgttaa
      121 acaaaaattt tgttttcgtt acatcttcaa catttgaaac atctcttgtt cctattcaat
      181 tttcagacgt ttacgttatt caattgttac gtatcgcatt acttcttgtt tcggatactt
      241 cgtgatccaa acatccatac gcattcacta tttataggtt tgtactctac acgcatgtct
      301 gggtgaaacc tgtacttcta acaactttgt ttgcttacac tgttctatcg agaaattctt
      361 ctgtctattt gatggtatcc tccttcctta catctatata atagcatcct ttggtagcgt
      421 ttgcaaatat aagcacttta aattttacgc tttcttaaca aataatcgat aagcccttta
      481 tttgaagtaa ataaaaaaag gatgttatag taaaataagt accttttttt gtacgaagat
      541 tttaaaggag gaataggatg gaagaataca agcagacaat agaagaagta aagaaggtaa
      601 cagaagcaga tccagatact gggttgtctt cacaagaagt ggatgaacgg cgaaaaaagc
      661 agggattgaa taaattcgat gaggcgccga aagaatcgat gatcaaaaaa ttctttcgaa
      721 gcttgtccga ttttacaacg atcatccttc ttgtagcagc ggtgatttcc ttttataccg
      781 catttgctac agaacatggg gatttatttg aaggactgct gatcatcgct atcgttgtga
      841 tcaactcggt attggcgatt gtccaagaag gaaacgcaga aaaagcactg gaatccttgc
      901 aagatatgaa taaacaaacg gcaactgtca tacgagacgg caaagtgacc actgttgagt
      961 cagagcaact ggtagtgggt gatattcttg ttttagagtc cggtgatgct atttctgccg
     1021 atgcccgttt gatcgaagca tcacaattac gtgtagaaga atcggcgttg actggagaaa
     1081 gtgaagcagt tgaaaaagat gcagcattta ttgctgaaga agatgagtca ttaggtgacc
     1141 aacttaatat ggtatttaaa ggatgtacgg ttgctgcagg tcgtgggaaa gcgatcgtca
     1201 ctgccattgg catggctaca gaaatgggta agatcgcgga tcttttgaac gaaaatacta
     1261 tgcaaaaaac acctttacag gtccgattga atcagctagg caaacgaatc agtatgatcg
     1321 ctttagcggc tgcggcttta gtatttgtga ttggtgaact gcaaggagaa ccactccttg
     1381 agatgttcat gacttcgatt tccttggctg ttgcagctgt accggaaacc ttgactgtta
     1441 ttgttacgtt gacacttgca tacggtgtgc agaagatggc gaggaaacat gcgatcatcc
     1501 gacagttgcc agcagttgaa acgctaggaa ccgctaatgt tatctgctca gacaaaacag
     1561 gaacgctgac acaaaatgaa atgcgcgtcc gccgggtatg gagcaaagaa gatgaagtaa
     1621 cgaatatcga agattcaatg acgaacagcg cgatggaaat attgaaaatg gctgcactat
     1681 gtacagatgt gacggtcgag caagaagatg acgaccttgt tatcaaaggt aatccaacag
     1741 aagtagccat cgtaagggct gttgaagaga attatcatac aaaggcagaa ttagaagaaa
     1801 aatatccacg agtaaacgag cttccttttg attctgaacg aaaaatgatg acaacagttc
     1861 accaaatggg cgaaaaatac atctcaatca ccaaaggagc attcgatgtt cttgctccgc
     1921 gctttagttc aggcgatgta gaacaagcgg cgatcgttaa tgatcgcttt ggtaaacggg
     1981 cactgagagt gattgctgtt ggttatgcta cttatgacga agaaccgcaa gatatttctt
     2041 ctgaagcact ggaaaaagac ttacgtttga ttggtctgat cggaatgatc gatccaccac
     2101 gtccagaaag taaaggagca atcaagcgag cgaaaaaggc tggcatcaaa acagtcatga
     2161 tcactggaga tcatgtggtg actgccagtg ccatagcgaa agaattaggt atcttgaatg
     2221 atccgtcaga agcactttca ggatcagaac tgcatcaatt atcagacgaa gaattagatg
     2281 cgcgtgtcaa agctctctct gtctatgctc gggtaacgcc agaagacaag atccggatcg
     2341 tcaaatcttg gcaacgtacg ggtgcagtcg tagcgatgac tggggatggt gtgaatgatg
     2401 caccagcgtt gaaagcaagt aacgttgggt gtgccatggg gatcacagga acagatgtgg
     2461 cgcaaagtgc cgcagatatg attttgacgg atgacaactt tgcgacgatc gtagacgctg
     2521 tcagtcaagg acgttcggtt tatcagaata ttcgtaaagc tatcaacttt ttgctaagct
     2581 gtaatatttc ggagatcttt attgttttga ttgcgatgct gttaggatgg ggagcaccat
     2641 ttacagctgt gcaactactg tttgtcaatg tagttgctga tggacttcca ggatttgctt
     2701 taggaagaga gccagcggaa cacggcatca tggatcagcc acccattccg aaaaatgaag
     2761 ggatctttgc tcgaggttta ttgcaaaaaa ttgccataaa tgcaggggtc ttcaccatcg
     2821 taaccttgtt tggttattat ttaggtagtt atgtcgatac tatcagccca tgggtagacg
     2881 caagtcagca tgtcggtcaa actgttgcat tcttgatctt agcttattca tcgattctgc
     2941 atgtgttcaa tgtacgcagc agccaatcga tcttcaaagt caatttagcg accaataaag
     3001 ctttggtaga aatggcgtta ctggcattag ctattacaac ggctgttgct ttgctgccat
     3061 ttacgcaaga actattcggc ctagtacaca tcagtttgaa tcactggttc ttggtaggga
     3121 ttttatctat cgtaccaatc gcggtgaatg aactgatcaa gttccatcga ttaccggaag
     3181 cagaagaaga ggaatgatta actgtttcta agttgatttt ctttttactg gaactataca
     3241 aaaaggaggt gtgacatgaa tgttgtcaca cctccttttt gctaatgggc tgaatgtttc
     3301 ttttactgcc tctcgataaa cggtgttctc ctgccacccc ctcggtcaca agtcacactc
     3361 tcttttaaat atcttttggc aattgttcat aaaatgctgc ttttgttgca gaaatgtatg
     3421 ggctgagcca tagataacca ataccagcag ttgctaatgc taagatatgc cagccgataa
     3481 atgaaagatc taaccagaaa agttgtcctt tataaccatc catcaatttt cgacttgcag
     3541 tgatcgtatc cagtacttta ggtgtttgtc ctgtttcttg gacgatatcg tagtaaataa
     3601 aatagctttg agaataagaa tagcttttaa tgattccagg aataactaat agcaaacccc
     3661 ataatgttgt aaagatcgag atcagcacag ctaagctgat cactccgccg ataaacaaac
     3721 ctttgaatcc acgaaatgca tctttgaatg gttcgatctg atctttttgt ccacgtaaaa
     3781 tatcaagata agtccaagaa ataccgctca tgaacaaagc gctaatgatg ctggaaataa
     3841 ttccgccacc gcctcctgaa ctaccgcctc ctgaagttgt cgcttctgag acgctcgctg
     3901 atccatcata tatggtggtg gcaaacaaga taataggaat cataataaga agaatagtag
     3961 caataccaat caatgtaggg attagattta gtaaaacagc ttgtccccaa cgtcctttta
     4021 gactctcttt tgcttggcgt tttaattctg cagaagattg catgattttt ccctcctttt
     4081 ctttaataac accaatatac catgtatcaa aaaatatttc tgtcataatg tttttctttt
     4141 ttttgttatt cataaaaaaa ggataaaaaa aagaatatta aataaagtag aaggaagccg
     4201 agggaacttg caaaaagcac ttgaaacgat tatgatggtg ggagttgtca agatatttta
     4261 tatagaaagt agggaaatga atgacgcaac ctgccattcg ctatcgttta atcaagaaag
     4321 aaaaacatac tggcgcgcgt ttaggggaat tgatcacgcc acacggaact ttccccacac
     4381 caatgttcat gccagtagga acattagcta cagtaaaaac aatgtcccca gaagagttga
     4441 aagaaatggg tgctggcgtt attttaagta atacatatca tttatggcta cgccctggtg
     4501 aagacttagt agaagaagct ggcggactgc ataaatttat gaactgggat caaccgattt
     4561 taacagattc aggcggcttt caagtttttt cattaagtga tatgcggaat atcgaagaag
     4621 aaggcgtgca tttcaaaaat cacttgaacg gttcgcgtat gtttttatca ccagaaaaag
     4681 caatcaacat ccaaaataaa ttgggctctg atatcatgat gagttttgac gaatgtccac
     4741 cattcgatga aagttacgac tacgtgaaaa aatcagtaga acgtacgtct cgatgggcag
     4801 aacgaggatt gaaagctcat gctaatccag accgtcaagg attatttgga atcatccaag
     4861 gagcagggtt tgaagatctt cgtcgtcaaa gcgcgaaaga tctagtcggg atggatttcc
     4921 ctggttactc aatcggcggg ttatctgtcg gggaacctaa atcagaaatg aatcgtgtat
     4981 tagaattcac tacaccgttg atccccgaaa acaaaccacg ttacttgatg ggtgtcggtg
     5041 ctgctgattc attgatcgat ggtgttatcc gtggagtaga catgtttgac tgtgtcttgc
     5101 ctactcgaat cgctcgaaat ggcacatgta tgacttctca aggccgtcta gtagtgaaaa
     5161 atgcgaaata tgcccatgat ttccgtccaa ttgatgagaa atgtgattgt tatacatgta
     5221 aaaactatac acgtgcctat atccgccatt tgatcaaatg tgatgaaaca tttgggattc
     5281 gtttgacttc ttaccacaat ttatacttct tgttgaatct aatgaaacaa gtacgtcaag
     5341 caatcatgga tgataatttg cttgaattta gagaagcctt ttttgaagaa tacgggttca
     5401 ataaagaaaa cgcaaaaagc ttctaaagga aaatctttta aaaattaagt aaaaaactag
     5461 tgttatcagc atttttctgc taaagtgttt tttgtagata cagaattagt gaggtgaaaa
     5521 aaatgggaac attaccaatg cttgtgatgt ttatcgcgct attagcaatg tggtttttta
     5581 tgtcacgttc gcaaaagaaa caacagcaag aacgtcaaaa cttgttagat agcatgaaac
     5641 caggtgattc agtcgtaacg atcggcggat tacatggagt tgtttcagaa atcgacaatg
     5701 acaaacggac agttgtttta gactgcgaag ggatcttcct tgagtacgat cgtgcagcaa
     5761 tcaaaacggt caaaccaggg actgtcgtaa caaatgatgc aacgactact gttgaaacaa
     5821 cagaagaacc agctgagaca gttgaagtaa aaactgaaac aacagaaacg ctggaagaga
     5881 cagaagagaa ggaagaaaaa taagtatcaa agcttattta aagacgaggt agggcagaaa
     5941 gatgtcctac ctcatttttt attcaaaaaa gaaagagata agagcatggg atatattgct
     6001 caatattgaa taatcgggtg tgtcatataa ataataataa ataactttat atatttttct
     6061 atacaaacac ctgtaaataa agcaatttta tatttaaaaa taactgtgaa aaaaatcaca
     6121 aaaaagtgtt tacatagaaa aataaatatt gtatgatata catgtgaatt atttaacaaa
     6181 taaccatgac ccattaggag gataatgatg gctaaagtaa tagaaaaaga aaaaacgaag
     6241 acaattgacg tacaagcaat gattgatgat ttggcagaaa aagcaaatgc agcattgaaa
     6301 gaaatggaaa gctttgatca agaaaaagta gaccatatcg tgcatgaaat ggcaatggca
     6361 gctttggatc aacatatgcc attagcgaag atggctgtag aggaaacagg ccgcggtgtt
     6421 tacgaagata aagcaatcaa aaatatgtat gcgtccgaat atatttggca taatatcaaa
     6481 catgataaaa cagttggtgt gatcaatgaa gatgtccaaa aagggttgat tgaaattgct
     6541 gaaccagtcg gtgtggtttg cggagtaact ccaacaacga atccgacttc cacaacgatt
     6601 ttcaaatcaa tgatcgcgtt gaaaacaaga aatccaatcg tttttgcttt ccatccaagt
     6661 gcccaaaaat cttctgcaga agcagcacga gtggtacgtg atgctgctat cgctgccgga
     6721 gctcctgaaa attgtatcca atggatcgaa catccttcga tcgaagcgac ttctatgcta
     6781 atgaaccatc caggtatcgc gatcgtctta gcgacaggtg gagctggaat ggtcaagtct
     6841 gcttactcta caggaaaacc agctttaggt gtaggtccag gtaacgtacc agcttatatt
     6901 gaaaaaacag caaaaattaa acgtgcagtg aacgatttga tcgtttcgaa aacatttgat
     6961 aatggaatga tttgtgcttc tgaacaagct gtgatcgtgg ataaagaaat ctatgcagca
     7021 gtaaaagcag aattccaagc acaccaagtt tatatcgtaa aaccagatga attgcaaaaa
     7081 ttagaagatg cagtgatgaa cgaaggaaaa tatgcggtca atccatcaat cgttggacat
     7141 tctgcgatgg aaatcgcaaa attggcagga atcagtgtac caaaaggaac gaaaatgctg
     7201 attgctgaat tggaaggcgt aggcccagat tatccgctat caagagaaaa actttctcca
     7261 gttcttgcca tgatcaaagc taacaacacg gaccatgcgt ttgatttgtg tgaaggtatg
     7321 ttgaatcttg gaggattagg acatacagca gttatccatt cagaaaacga agagttgcat
     7381 gtcaaattcg gtcttcgaat gaaagcttgt cgtattttag tgaatacacc atctgcagaa
     7441 ggcggcatcg gtgatatcta taacgaaatg attccgtcat tgactttggg atgcggttct
     7501 tatggtaaga actctgtttc tcgtaacgtc tctgctgtaa acttaatcaa tgtcaaaact
     7561 gtagcgaaac ggagaaataa catgcaatgg ttcaaattac cgccaaaaat cttctttgaa
     7621 aagaactctc tattgtactt agagaaaatg gaaaacgttg aacgtgtcat gatcgtttgt
     7681 gaccctggta tggtccaatt cggttactgc gatacagttc gtgaagtatt ggcacgacgt
     7741 aaaaatgatg tgaagatcga agtcttctca gatgttgaac cgaacccatc gacaaatacc
     7801 gtatacgcag gaacgaaact gatggcagac ttcaagccag atacagtaat cgctcttgga
     7861 ggcggttctg caatggacgc agctaaggga atgtggatgt tctatgaaca cccagacaca
     7921 tctttctttg gtgcaaaaca aaaattcttg gatatccgta aacggacata taagatcgac
     7981 aaaccagaaa aaacacaatt cgtatgtatc ccgacaacat cagggactgg ttctgaagta
     8041 acgccatttg cggtcatcac tgacagtgaa acacatgtga aatatccgtt agcagattat
     8101 gcattgacgc cagatgtcgc aatcgtcgat cctcaattcg tcatgtcagt tccagcatct
     8161 gtcacagcag ataccgggat ggatgtgtta acacatgcaa tcgaatccta tgtttcagtc
     8221 atggcttcag attatacacg tggattgagc ctacaagcaa tcaagttagt ctttgactat
     8281 ttagaaaaat cagtaaaaac acctgatatg gaatcacgtg aaaaaatgca caacgcttct
     8341 acaatggctg gtatggcgtt tgctaacgca ttcctaggta tttgtcactc agtcgcacat
     8401 aaaatcggcg gggaatacgg gatccctcat ggacggacaa atgcgattct tttaccgcat
     8461 attatccgct ataatgcaaa agatccacaa aaacatgcga tgttccctaa atatgactat
     8521 ttccgtgcag atacagatta cgcagatatc gcaaaattct taggtctgaa aggcgaaaca
     8581 acagaggaat tagtcgaagc tttagcaacg gctgtttatg aattaggaaa atctgtcggc
     8641 atcaacatga gtctaaaagc tcaaggagtc acacaagaaa cactagatac aaccgtagac
     8701 cgtatggctg aattagctta cgaagaccaa tgtacgacag ctaatccgaa agaaccattg
     8761 atctctgaat tgaaacagat catcattgat gcttacaacg gataagcaaa agaaagcgta
     8821 gaaaaaagat aagaaaatag atgaaaaaga acttggaaaa cgttgtttct ccaagttctt
     8881 tttttaattt ccaagtaact gaaagttact tttgttattt aacatttagg tcaattttag
     8941 acagtttttg ttcaaaaagc gatatttata gtggacggta ttactgctat attaaggata
     9001 taaaatgaaa gcgtttaaaa aggtggcgta aagatgatta ttaaagaaga gatttttgta
     9061 cctaaagaat tagtgaaaga aaaaattgac ctgctcgttg aaaacctgac aacgatcaaa
     9121 gacgataatg gtgaattttt gttggacttt gatggactga aagtagatga caaaagctgg
     9181 acagtgtgga attggccaca aggtgtcggt ctatatggta tttataaaaa ttaccagatg
     9241 acaaaaaatc ctcgcgctta tcaagtggtc aatgaatggt ttgaggatcg tatggaagaa
     9301 ggcgctccgc ccaaaaacgt caatacaatg gcaccgctat tgactatggc ttacttgtat
     9361 gaagacacga aagattcacg ctatttgcct tatttagaac aatgggcaga atgggtcatg
     9421 aatgacatgc ctcggacaaa tgaagacggg ttacagcatg ccacatatgg accggaaaat
     9481 aagaatcagt tgtgggacga tacattgatg atgacagtgc ttcctttggc aaaaatcggg
     9541 aaactgttga atcgcccaga atatttagaa gaagctcgtt accagtttat gatccatatc
     9601 aaatacttga tggataaacg aacaggattg tggtatcacg gctggacgtt tgaaggaaat
     9661 cataactatg ccgaagcatt ttgggctcgt ggaaactgct ggttgacgat tgctattcca
     9721 gagatcattg aaatcttaga attatcgaaa gaagatgcat tgcgcaaatt attgatcgaa
     9781 acacttgaag cacaagtgcg tgcattaaaa acttatcagt ctgaaagcgg tttatggcat
     9841 acgttgttgg atgatccttc ttcttacgta gaatcttctg caactgcagg atttgcttac
     9901 ggtattttga aagcggtcca taaacgttat ttaccacaag aatataaaga agtcgcttat
     9961 cgtgctatcc aaggattgct tgaacaaatc gatgaaaaag gagaagttca aaacgtttca
    10021 atcgggacag gaatggggga cagtttagat ttttatcgga atatcggaat cacagcaatg
    10081 ccttatggac agtcgttaac ggtgctttgt ttgacagaat tgctcgtctc ttattgttaa
    10141 aagaaaggaa acccatatga aaaaaacatc actgctgttt gcagcaagtt cgcttagcct
    10201 aggtctgcta ggtctaagcg gctgcggaaa taattctagt gtggcaactg tcgcagatgc
    10261 agatgtaaat gagatagtta ccttgcgctt tgcttatgca agcaacagcc agccagtaat
    10321 tgatgcaatg aatgaatttg ggcgtttagt aaaagaaaaa acagatggtt ccgtacagat
    10381 ccagtatttc ccagatggac aactgggtgg agaacgtgaa ctgatcgaat tgacacagtc
    10441 aggagcagta gatttcacaa aagtaagtgc ctcagcgttg gaaagtttct ctaaagatta
    10501 ttcgattttt tcagttcctt atctattcaa tgatgaagaa catttcttta aggtgatgga
    10561 taatgaagaa ataatggagc caatctacca atcgaccaaa aatttaggat ttaccggatt
    10621 gacctattat gattctggtc agcgcagctt ttatatggta gacggtccga tccatacgcc
    10681 ggaagatttg gagggaaaga agatccgtgt gatgcaaagc gaaaccgcta tcaaaatggt
    10741 agagctttta ggcggttcgc ccgtacctat gggaagtgat gaagtgtaca cgtctcttca
    10801 atccaatttg atcaacggat cagaaaacaa tgaatttgtc ttgtatacag ctggacatgg
    10861 tggtgtggct aaatactatt cctatgatga gcatacacgt gtgccagata tcatcatcat
    10921 gaatgatgcc atcaaagaac agctaactga tgagcaggaa aaagccattg aagaagcagc
    10981 gaaagaatca acggtttttg aaattgaagc ttttgcaaaa gcaattgaag aagaaaaagc
    11041 tttagcacaa gaagaacatg gagtccaatt caatgatgta gataatacac cgtttcgaga
    11101 ggcagttgcc ccacttcatg atatattcaa aaacgatcct acctacaaag acctttatca
    11161 aaagatccaa gagcaaggag cgtagctgtg atgaaaatga ttttaaacaa ggtattagag
    11221 atcctgggag ctgttttgct tgttgggatg gtcgctgttg ttttatggca agtattttcc
    11281 agaacggttt taggaaatcc aaatacggtc acggaagagc ttgttcgatt cggtcttgtc
    11341 tggtttgcca tgttgtcttc cgcgtatgtt gtgggacaaa aagcacattt agccgtaacg
    11401 gttttaagtg aaaaattaac tggcaaaaaa agtaaaattt tagaagttgt tgttcaaagt
    11461 ttatttctgg tatttgctgc gatgatcatg gtgtatggcg gatggaatgc tgtcacattg
    11521 acaatggggc agatctcgcc ttctttaagt attcctatgg gatatgttta tctgtcagta
    11581 cctgtatcgg gggtactcat cattatctat agcctgatca atctaatcga tacattaagc
    11641 aacaagccag caattcaaga aaaaatataa aaatggagga ataaaatggc aatagaagcc
    11701 ggattagtgt tattttttgt atttgttgtg ttgcttgtat tagggatgcc gattgctata
    11761 agtattgcat tctcatcgat gatgacttta ttgttagtta taccgtttga tgtttctgct
    11821 tttagttcag ctcaaaaaat ggtgggaagt atcaatagtt tttcgctgat cgctattccg
    11881 tttttcgttc tctcgggcat tatcatgaat aatggaggga tagctaagaa actagtggat
    11941 tttgcgatgt tgttcgtcgg gcgcgtgccg ggggctttgg ctcatacgaa tgtgttaggg
    12001 aatgctttat ttggttccat ctctagctcg gccattgccg cttctaccgc gattggcgga
    12061 gtgttgatcc ctcagcaagt ggaagaagga tatgaccgga agtttgcgac agcggtcaat
    12121 atcgcgtcag ctccgacagg tatggtcatt cctccaagta ctgcttttat catgtattca
    12181 cttgttgctg gtggtgcttc gatctctgct ttgtttatgg gaggttatct cgtaggcgct
    12241 ttgtgggcgc taggaatcat gctagtagca ttcatcgttg ctaaaaagaa taaataccct
    12301 gttgtcgaaa aaggacagat ggctcatgct ggaaaaataa taaaagaggc gattcctagc
    12361 cttctattga ttgtcatcat tatcggtggt atcttgacgg ggatatttac agcagtagaa
    12421 gcttcagcga tagctgtcat ttactccctg ttgattgcta tgttttacta taaaacggta
    12481 aaactaaaag atatacctaa tatgttgttt caatcagtag caatgtcagg gacgatcatg
    12541 ttcttattgg ctacttcttc catgatgtct ttcgccatgg cgtttaccgg tattcctcag
    12601 gcaattagtt cgttgattat gggcgtaacg gataataaat ttattattct gttattagtc
    12661 aatcttgtgt tattactggt gggtatgttt atggatgtgg cgcctgctat cttgattttt
    12721 acaccaatat ttttaccaat cgtcacaagt gtaggggttg atcctgtaca ttacgggttg
    12781 ttttcaatca tgaatctgtg tgtaggctcc atcacgccgc cagtaggtac aggactatat
    12841 gtcggtgcaa gtgtaggagg cgtaaaagca gaggcaatgc tgaaaccgct tcttcctttt
    12901 tatggggtta tcttagtcgt cttgtttttg attacttact tcccgcaaat cgtcatgtgg
    12961 ctacccaata tgctgagtta ggagaatagt tatgttgaac attacaatta gaggacatga
    13021 tctttccgaa gtccaaacga tagaagatct tgcagaaaaa acaaaagaac aagggattca
    13081 tacactgcag ctcgccttag gtctttcgtt tcctgaaaca ccttctggcg caaatgagat
    13141 caattctggg atgggaaatt atgtcaaacg agttttagaa aagcaagaag tgaccgtagg
    13201 aattttaagt tgctatatca atatgattca tccagattta acgatacgac aagagttgct
    13261 gacaaagttc gagcagtatc ttcgctatgc ttcttccttt ggtgcgtcga tggttgcttc
    13321 ggaaactgga tgtgttttgc cggaaatcca atatacggaa gaaaatttca cagatgaagc
    13381 atttgctgaa gctgtgtccg ttatccgtcg cttggtaaaa gctggagaaa aataccaaat
    13441 gatggtgggg atagaaccag gtttgaatca tccggtgtat tctttagcaa gggtagagca
    13501 gctgatccaa gcagtagatt cggactatct aggaatcatt ttagatccga ccaatttgat
    13561 cacaagtagt gattatcaag aacaagtcca attggtagaa gaagcttttg aacgttttgg
    13621 tgaaaagata tgtgcggttc atttgaaaga ttttcgtgtc gaacaggaaa aaatcgtgcc
    13681 ggtaaatttg ggagacggtg tgatcgagta cacaaaaatc aaagaaatca tcatgaagaa
    13741 tcgtccgtac ctgtatgtgg ttcttgaaga aacaaaagat gatgggattc gttatggaag
    13801 aagtcttctt gaataatgta aagaagacgt tggttaacta atatttagaa tggagggggc
    13861 ggggctagaa gatgccacgt ctcttctttt ttataagagt atataaaagc agctcttttt
    13921 gattacaaaa aacgtggtat aataaaattg tgcataagtg aacaaaagga ggtgcggcac
    13981 atgctccaaa agaaaatcag cggtgaacaa gtcaatacga tggtttctga tcagtatgaa
    14041 atctatcatg tcaaagatgt cgtcagccaa aataaaacga tctatcatca tcatgatttc
    14101 tatgagatcc atgctacatt aaagggagaa gcgacttttt atttgaacgg acgacaattt
    14161 acgatcaaag caggaagtgt gctgctcatc cattccaatg atttgcatcg tatcgtccgc
    14221 caatcttcag atgtattcga gcgtgtctat atctttgtca ccccttcttt tctagaaagt
    14281 cgttccacgc catggtctaa tctatcggct tgttttcaac caatgggaga gaagaggagt
    14341 cgtgtattgc aaatagaaca ggaagtattg aagcaaaaat tatcatttat cgaccatcct
    14401 cctgataaaa aaatttacgg tgaagacata aaatatgaac aagctctggt agaatacttg
    14461 atttttctca atcaagttgt acaaaaagaa gagagtgcgc aagaacagaa tgctgtagtt
    14521 cctaatgagc gtgtggaaca aatgttacaa tatatctcaa aaaatttatc tcatccgctt
    14581 tctttagagg aaatggaaaa gcagtttttt gtcagcaaat accatatcac acgagaattt
    14641 aaaaagtaca ctggatttac gtttcatcag tatgtaatga agaaaaagct gatctatgcc
    14701 aagcacttgt tgcgagaata ccgcagctct agtgctgtat atagtaaaag tggtttttct
    14761 tcttatccgc attttctgaa agcattcaag agagagttcg gcataacgcc taaagaattt
    14821 ttgaaacgtg atacacagaa acagttggtt cattatgaac attttgaaga tgaacaatga
    14881 gaatgatcac taaaaaataa ccgcagtagc tgctgttgtt tacatagaag cagaaactgc
    14941 ggttatttta tttttatcta tatatttcaa aatattttga aaaaatgacg tacatattat
    15001 atgaatcagc tgaatttacg aaagtctctc ggcgatagtc ctgtttttgc tttgaacagg
    15061 cggctaaagt aagcaaaatt ctcaatccct atttcttcgg aaatcattcg aaccgtaaat
    15121 tctgtatacc gaagaaggtc tttagcgtaa gaaagttttt tgctgatcaa ataatcgatt
    15181 ggtggagaac cgataaattt ggaaaaatct ttgctcagct gatatttatt caataagaat
    15241 tgttgttcta attgatcaag tgtaatcgtt tctttgaaat gttcgtctaa gtattgcttc
    15301 agtttgtaaa cgtaggcggg aatatcctct tcttcgaaat ctagctgata cttttgcaaa
    15361 atcagttcat tcagcaactc gtggatagct acagaggact ggaaatcggt acgggcattc
    15421 gtgccttgtt gcatgtggat caattctgtg atcaaatggt ggatcttgtt ttctgatgga
    15481 tcccctgttg aatggaaggt gttatggccg tcttttgtga actcctgata aaatgattgg
    15541 acgttctgac cattcaaatg gatccaatcc atttcccatg gttcttcgct gatcgtttga
    15601 taacgctgat attcttggca gtcaataaaa aataagtctc cagcttttag ctgttgctga
    15661 ttatcattat atgtaagcga acctttgcca gacaaagtaa actttatcaa gtaagaaggt
    15721 aaatgtgctc gttcagtata gtaagggatt ggtgctttga agtaaccgat ttcttggata
    15781 taaaaaaata aattcctgct tctttgtgta ggcgtcaaga tcactctttt tgagtcttcc
    15841 gaccatgagt ggttggcttt ttcccagtaa tccatgtaaa cactcccaac ttgtcaagat
    15901 aatgcaatta tataccaaaa tagtgtgaag caaaatataa gattctgtat tatgatagca
    15961 ttgttaataa atgataacgc tttattaata aagtgctaat caacaataaa gtaaaagagg
    16021 tggagaaatg aatccaacat ttgttgccat cgatatcggt gcatcaagcg gacgactaat
    16081 gaaaagtacg agggatgcaa aaggttcttt gatcttggaa gaagtacacc ggttcaaaaa
    16141 cggctttcgg aacaaagacg gtcacgatcg ctggaagatc gattatctta tcaaagagat
    16201 tttgattgga tttgaaaaat taaagcagac agggattgat cgcctttttg cggggatcga
    16261 tacatgggca gtcgattact gtctgattga tgaacaaggg gatcggataa atgatccgat
    16321 tgcttatcgg gacaagcgta ccaatggagc agtagaacag ttttctgaaa tctattctct
    16381 agataagttg tatgagcaga cagggattca gatccagcct ttcaatacct tgttccaatt
    16441 gtttgctgaa gaaaaagaaa atttggcaaa agcacataaa ttgttactga tacctgatta
    16501 tttagggtat gtctttactg gtaacatggt gacggagaaa actaatgcat ctactatgca
    16561 gctgctgaat gcagggacaa aagaatggga aatagaactt cttgaaaaaa tcggtgtctc
    16621 gaaggaatta tttccaccat tgacagagcc gggaacgata ctaggagatc tgcaaaaaga
    16681 acaattttca aaatatgatt tgccagatgt gacctttatc acagtagcaa gtcatgatac
    16741 ggcgtcagct gtattaggaa cgccaggtca aggagaacgt tggggttata tcagcagtgg
    16801 gacatggtcg cttttaggga ttgaaacaaa gatcgccaat gtttctcgca atgctttttc
    16861 tgaaaattat acgaatgaat ggggtgccca taacacggtg cgttttttga aaaacatcat
    16921 ggggatgtgg ttgatccagg aagttgcccg aatgcaagag tacgagtaca gttatgcgga
    16981 attggcagag cttgctgcaa aagaaaaacc gctgcagcaa gtgatggaaa tcaatgaccc
    17041 tcgatttttg aatcccccaa atatgataga agagattcag caatactgtt ttgaaacaga
    17101 gcagccagtc cctgtctcat cgggagctat cgctcgttgt gtgtatgata atcttgctct
    17161 ttgttacgca caagagctga tcaaagtaga acacttaact ggaacgaaat tggaaaagct
    17221 gcacatcgta gggggcggat cgaataatcg tctactgaat caattgacag cagattatgc
    17281 cggaatcatt gtagaagcag gacctagtga agccacagca atcgggaatg ttgccatgca
    17341 aatgctcagt acaggtcagt tttcgaatat agaacaagca agaaatgtaa tcaaacagtc
    17401 gtttccatgt gaaacttttt acccagatga aaataagcaa aacacgatgg aatggtacgt
    17461 gaataaaatc aaaggagtaa tcgtatgaac acgattgaaa gaaattacga acaagcaaaa
    17521 gaaaaatatg caactatcgg tgtagataca gatgctgtac tagaaaagat acaggacatc
    17581 aaaatttcta tgcattgctg gcaaggagat gatgtcaaag gtttcttgac accggatggc
    17641 gaattgaccg gtggaatcat ggcgacaggg aattttccag gagccgcacg aacacctgaa
    17701 gagcttagac aagatctgga gaaggcttat tcgttgatac cgggcaaaca caaattgaac
    17761 cttcatgcta tctatttgga tacagaagaa tctgtcgatc taaatgaaat tgagccgaaa
    17821 cattttgaaa aatgggtaga gtgggcaaaa aaagaagaaa tcggtcttga cttcaatccg
    17881 actttctttt cgcatccaat gatgaaagac ggctttacat tggctcatcc agataaagaa
    17941 gttcgtgaat actggatcga acacgggaaa agaagccgca aaatcgcgga gtactttggg
    18001 aaagaaactg ggcaaacaag tatcaataac ttttgggtac ctgatgggat gaaagataat
    18061 ccgattgatc gttttacccc acgggaacgt ttaatggaat cactcgatga aatttttaca
    18121 gaagagttag atgaacggta tgtacaagat gcagtagaaa gcaaactatt tggtttaggc
    18181 gctgaagctt atacagtcgg ttcccatgaa ttttatatgg gttacgggtt gactcgtgac
    18241 aaacttgttt gtctagatgc tggacatttt catccaacag aagtgatttc caataaatta
    18301 tcttcattag ctttattcag caaaggaatc atgttgcatg tttcccgtcc agtgcgttgg
    18361 gattcagacc atgtggtttt gatggatgat gaattgcagg aaatcgctaa agaattagtc
    18421 cgtaacgaat tgttggaaaa aacaaatatc ggtctggatt tctttgatgc aacgatcaac
    18481 cgtatcgctg cttgggtcat cggtacgaga aatacacaaa aagcactgct gaaagctatg
    18541 ctggaaccag ttgagcgatt gaaagaaatg gagctggctt ttgactttac ttcaagaatg
    18601 gcttatacgg aagaattgaa agatttcccg tatgccgatg tatggaatta tttctgttac
    18661 aaaaatcaag ttccagttgg tttggattgg ctggaagaag tccaggaata tcaaaaagac
    18721 gtgttggaat taagaaaata ggagtgtggc tatattgaaa aaaatagata ttttacaagc
    18781 gccttatgtg aaagaaatga tcgaaacgac gtcgaatctt tatcgcttgg gatgggatga
    18841 aagaaatggc gggaatattt cttatttact aaaagaagaa gagatcacac cgttcttgga
    18901 tcctgaaaaa gtgatccgcc gcatctcgat gatttttgat gccagccgtt tagcaggatg
    18961 ctattttatt gtaactggtt caggaagata ttttaaaaat gtagcgagcg aacctgccga
    19021 gaatcttgga atcgttcgag ttgctgaaga tggcaaaaca ctggaacttt tgtgggggct
    19081 ggaaaacgaa tgccttccta caagcgagtt gccaagtcat ttcatgagtc atatcgcccg
    19141 tttagaagta gacccagata atcggatcgt tatgcattgc catgctagtc atctattagc
    19201 gatgagtttt acgcatgaat tagacgaacg ttcctttagt cgtacgctat ggcaaatgtg
    19261 tacggaatgc ttagttgttt ttccagaagg aatttccatc attccgtgga tggttccggg
    19321 aacaaatgag attggggaag caacagctga aaaaatgaaa gaaactcgat tggttttatg
    19381 gccacaacat ggaatctacg ggtcaggaaa agacatggat gaagtctttg gtttgatcga
    19441 gacagcagaa aaggcagcag aagtctatac gtacgtcaaa gcgcaaggac caatcttgca
    19501 aacaatcacg gacgaaaacc tgtggcattt agcagatgcg tttggtgtca ctccaaaagc
    19561 aggttatttg gaggaagttc atacgaaagc aggtgtctga catggtgaaa aaagcttttt
    19621 gcatgaaagt ttacccagaa aaacaagaag aatacaaaaa aagacatgat gaactttggc
    19681 cagaaatgcg tacagcactt cgtgaacacg gggtcatcga ctattcgatc tatcttgatc
    19741 cgagtacaag tttgttattt ggttacttag tgatcgaaga tgaaaagtta tgggaaaaaa
    19801 tggcaaatac atctatcaat caaaaatggt ggaagtacat ggaagatatc atggagacaa
    19861 atccagatgc ctctccagtc agttgggaat tgatgccagt ctttgaactg tagcaacaag
    19921 caactgggca accggttgct tggggttctt tcgtttttat tgtgaaaaaa aatacaaatt
    19981 aggaggaata gaaaatgagt aatcgaatga ttttaaatga aacatcgtat tttggaaaag
    20041 gagcgattga gtcgatcgtc cctgaatttc agcagcgagg attcggcaaa gcagctgtca
    20101 ttactgacaa aggattgatc gagcacggta tagcaacaaa agtaacagaa cttctagata
    20161 aagcagcaat cgcttatgct ttatacgacg ggatcgtacc taatccaacg atccaaaatg
    20221 taaaagatgg agtggctttt gttaaagagg cagaggcaga ctgtttgatc gcaatcggtg
    20281 gaggttcgcc aatcgatacg gcaaaagcca ttgggattat tttgacgaat ccagagtttt
    20341 cagacgtcat tagtttagaa ggtgttgctg atacgaaaaa tccatgttta cctatattag
    20401 ctataccaac gacttctgga acagcagcag aagtaacgat caactacgtc atcacagatg
    20461 aagtaaatca ccgaaaattt gtttgtgttg atcctcatga tatcccaatc gtcgcgttca
    20521 tcgacagcga tatgatgatg ggaatgccga aaaaattggc tgcatcaaca ggtatggatg
    20581 ctatgacgca tgctattgaa gggtttatca caaaaggcgc ttgggaaatg actgatatgc
    20641 tgcatttaaa agcaatcgaa atcatcggcc attctttgga agtttctgta gatggcgatc
    20701 aaaatgggcg agaaaaaatg gcattaggac agtatattgc gggaatgggc ttctcaaatg
    20761 tcggtttagg actggtacac gggatggctc acccgttaag tgcatggtac aacattcctc
    20821 atggcgtagc gtgtgcagca cttttgccaa ctgtcatgaa atataacaaa gaatatactg
    20881 gagaaaagta ccgtgagatc gctcttgttc tagggattaa aggagcagct gaaatgtctt
    20941 tagaagatgt aagagaagcg gcttgtggtg agatcgatcg gttgagcaaa gcggttggaa
    21001 tcccagaaac catttctgaa ttaggtgtaa aagaagcaga tattccagca attgcagaag
    21061 atgctttgcg agatgtatgc acaccaggaa atccaagaga aacgacagta gaagaaatca
    21121 ttgctttata tcaaagtttg atgtaaaaac gaagcggatc ttcaacatta aattgcctgt
    21181 aaagagaaat ggtagtttat atctggatat ctcttttaaa ttgatggtat ttccgctata
    21241 atttttctta taaagaaata ggagaatatt atatggaaaa taaaaagcct tatggaactg
    21301 tattgatcaa agcctctaaa atactagact atttagcgga aaaccaagat gtctctttgc
    21361 agacgatcgc aaagggtgtg ggaatgacct cttctacagt cttgaaaata ctagatactt
    21421 tgttgatgat cggctacgta aataaaaatt cagagaaaaa ctatcgttta ggtgcaaagc
    21481 ttattcgcta cgcgaataaa aacattgaac aaatcgattt ggtagagttg actttaccgt
    21541 ttttagaaca gctgcagcaa aagatcgatg agactatcca cttaggggta ttggacaaca
    21601 atgagatctt gtacgtgaac aaactagatc caaaacatca aacgatccgc atgtcttcaa
    21661 aaatcggaat cacccgacca ttatacaatt ctgcgatggg caaagccgta ttagcagaat
    21721 tcagtgaaga gcagtacact gattatcttg aaaagcatcc gttgatccct tacacagaat
    21781 atacgatcac caatgcatta cggttgaaaa aggaaatcca aacggtaaaa gaaacccaca
    21841 tcgcatttga cgatgaagaa atcgaacgtg atattttttg tataggagcc tcaatcgtga
    21901 aaaacgaaca aatcattggt gcatttagtg taagtatgcc gaaatatcgt ttaacagatg
    21961 agacaaaaga acaaataatc agtgccctca agcaaacaaa aagcgaaatc gagcaaagaa
    22021 ttcaaaaata atgaaaaaag cgtttgcaat ttttcttttc tgccgtataa tatgggtata
    22081 gatttccaag ttataaaata aaatttctaa ataggaaata ggtggagaag atgaaaaaaa
    22141 ttgatatttt atctcgattg aaaaacgccg gagtgattgc ggtggtacgc ggaaaaagca
    22201 aagaagaagc tttgaatgct tgccacgcaa tcatcaaagg tggtctaact ggtattgagt
    22261 tgacttttac agtccctcaa gcagatcaag taatcaaaga acttttgtca ttctacaaag
    22321 accaaccaga aatagtgatt ggcgcaggca cagtattaga cgctgtcaca gctcgcttgg
    22381 ctatcttagc tggcgcagag tatattgtta gcccttcctt tgatcaagaa acggcagaga
    22441 tgtgcaatct gtatcaaatt ccttacttac caggatgtat gactattacc gagatcaaaa
    22501 cagcgctgaa aagcggggta gatatcgtca aactatttcc tggaagcgct tatggaccaa
    22561 gtatcatttc tgccttcaag gcgccgatgc ctcaagtcaa tatcatgcca actggcggtg
    22621 tgagtctgga caatatgaaa gagtggttcg atgctggtgt cgtaacagtc ggagtaggtg
    22681 ggaacctttt agcacccgca gctacaggag attttgacaa agtaacggaa gtcgcgcaac
    22741 agtatgcagc aaaaatgaaa gaaatcaaga ggtagctgct tatgggaaaa gtagtgacac
    22801 tcggagaaat catgttgcga ttgtccacag agcagggaac ccgtatcgat tcaagtgaac
    22861 gattcgctgc ccattatggc ggaggggaag caaacgtagc aatttcttta gctaattacg
    22921 gacatgaagc gatttttgct acaaaagtac ctgataacgc attgggaaaa gcagtcaaaa
    22981 agcacttgca atgttatgga gtagatacga aacaggtatt atctggtgga tcaagactag
    23041 gtacttatta tatggaaact ggtagtggcg aacgcgccgc ctcagtgatc tatgatcgtg
    23101 ccggatcaag ttttgctgaa atggatcatt tggaatggtc gctagaggag ttattccaag
    23161 gaatagatat atttcatgtt tcaggaatca ccccagcttt gtctaaaaaa tggcaaaaaa
    23221 tgacgaaaca ggtgatagaa gctgcaaaaa aagctggctg cctgatcagc ttcgatatca
    23281 actatcgtgg aaaattatgg acacagcaag aagccagcga agtaatccat cagcttttac
    23341 ctttagtaga tatctgctca gctggaaaaa tggatgctct ttatttgtta ggtatcgaga
    23401 aagcgccaga agcagaagaa caacctctaa tttattatta tcaaaaaatg caggaaaagt
    23461 tcccgaatat tcaggtgttt tattcgacca agcgtaccgt tcattcagca agtgaaaatg
    23521 aattgaaggg gacattgtgg atgaaccatg aatatgtgga atcccaagtc catagaatca
    23581 ccccaatcgt ggatcgagta ggtggcggag atgcttttgc aggtggcgtg ctccatggga
    23641 ttttatccaa tatgtctccg caagaaatca ttgattttgc tacggcagct tctgccttga
    23701 agcatacgat ccatggggac tgcaaccaat ttagtcaaga agaagtcgca caatttttag
    23761 catgcggctc tggaaaaatc attcgataga aggagtagaa gaaaatgcaa gaaatggaaa
    23821 cacgttatac acacagtcca gaagatatcc gtcattattc aacggaacaa ttgagaaaag
    23881 aatttttagt agaaaaggta tttgaaccag ggaaaatcag tttgacttat acgcacaacg
    23941 atcgaatgat ctttggtgga gtgacaccta ctgaaaaaga attagaaatc acattagaca
    24001 aagaactagg tgttgattac ttcttagagc gtcgtgaact aggtgtgatc aatatcggtg
    24061 gaccaggatt catcgagatc gatgggcaaa aagaagaaat gaaaaaacaa gacggatact
    24121 atatcggaaa agaaacacga catgttgtat tttcttctca agatgctgaa aacccagcta
    24181 aattctatat tagttctgtt ccagctcatc ataaatatcc aaatgtaaaa atcagtatcg
    24241 accaagtaaa accaatggag actggtgaag gcctgacact gaatgaacgt aaaatctacc
    24301 aatacatcca tccaaatgta tgcgaaagct gtcaattaca aatgggttat acgattttag
    24361 aaccaggaag cgcttggaat acgatgcctt gtcatacaca tgaacgtcgt atggaagctt
    24421 atgtctactt tgattatgcc aatgaagata cacgtgtgtt ccacatgatg ggcaaaccag
    24481 atgaaacaaa acatttagtt gtagacaatg aacaagccat tatttcgcca agctggtcga
    24541 tccattcagg tgtaggtaca agcaattact cattcatctg ggcaatgtgc ggagaaaata
    24601 tcacctatac agacatggat atggtgcaaa tggatcaatt aaaataagca taagggagag
    24661 aaaatgatgg aatttagtat ggatatgttt cgtttagatg gaaaagtagc attagtcacc
    24721 ggtgctgtct atggtattgg atttgagatt gcacgctctt tagctacagc aggagcaaaa
    24781 atcgtattta ataacttgaa tcaagaatca gttgatgaag gtatagcgca ttataaagaa
    24841 gcaggcatcg atgcaaaagg ttatgtctgc gatgtgaccg atgaagaagc ggttcaagcg
    24901 atggttcaac agatcaaaga agatgtaggt tcagttgata ttctagtcaa caatgcaggg
    24961 atcatcaaac ggacaccgat gatcgaaatg gatgcggcag acttccgcca agtaatcgac
    25021 gtggatttaa atgccccatt catcgtttca aaagcagtta ttccggatat gatcgaaaaa
    25081 ggcggcggta aaatcatcaa tatctgctcc atgatgagtg aattaggacg cgaaacggtc
    25141 agtgcttatg ctgcggcaaa aggcggatta aaaatgctga cgaaaaacat cgcttctgaa
    25201 tacggtcaat acaatatcca atgtaatgga attggaccag gttatattgc tacaccgcaa
    25261 actgctccat tacgcgaaac acaagaaaac ggtgaacgtc atccattcga tcaatttatc
    25321 gttggacgta cgccagcagc acgctggggc gagccaatcg atttggctgg accatctgtc
    25381 ttcttggctt ctagcgcatc tgatttcgtt aacggccatg tcttgtatgt ggacggaggc
    25441 atacttgcct atatcggaaa acaaccttaa aagagcttta gtacactgtt tagtggagag
    25501 gttgtgaaat cagcggattg aacgaatacc gaaggacagc tgattaaaca tcatttattc
    25561 gaaaaaagag gctgggacag aagcatttaa ctccaagaaa taagaaggaa ttcacgaaaa
    25621 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ttacttccgc
    25681 cgtttgtacg tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt
    25741 tctgtgcgtc ttccatactt cactaagtcg atccctcttg cttcgcacca atccttcact
    25801 ggtccggaaa agatcagaga ttgttggtgt agggccgcgg tattcgttgc gccgaccata
    25861 gtataaagca gacgaagctc ttcttgccat tgcttcatca gtataatagt ttcttctacg
    25921 ccgtgattca tcagatgcgt cagtacggtt cctgaagtac ccacggcatt tgcgccgaga
    25981 caaagggctt taaatatgtc ataggcattg cggatacctc cggaggctag gatttccata
    26041 gaagtgtctg cttcatttgc ttcaagcaat gaagagactg tcgattgccc ccagtcagct
    26101 aaataactca gttcccgctt ggagcgacgg gcgttttcga tctgggtgaa gcttgttccg
    26161 cttcgaccgc tgatatcaac tgtatgaact cctaaagcag ctagatcatt gagcgtttct
    26221 cttgtcatgc caaaaccgac ttcttttacg atgaggggga cgtcaatggc tgtttgagtt
    26281 tcttgaataa gtactttcca attggtaaaa tcacggtctc cctcaggcat aaccaactct
    26341 tgaggtgcat tcaaatgaat ctgtaaggca tctgcgtgaa acaatcggat agcttctttg
    26401 gctctttcga cagaagtccc tgcaccgatg ttggcaatga ttttcccgtg aggatattct
    26461 tgtcgcataa tcgtataagt atcggctaaa gaagggactt tcaaggcagc gctgactgaa
    26521 ccagtggcaa tcatcaaatc tgcttctctt gcgacgattg caagatcttg gttgattttt
    26581 tttgtttttt cgcttccgcc agtcatcgca ttgatataaa atgggctgct tagtgtaaac
    26641 ccaactgcct gtgtacttag atcgacatca gaaactgcta tttgcggcaa agggttatgg
    26701 atgatccgta cgaagtcaaa ttcgtttttt tgtttatcat gaaaggcttt agctagtgaa
    26761 acatgttcgt cttttcgatt catcggtttt cctttctttg atcgctatag acatgtaacg
    26821 gcagtggagt gatttctgct ttttcccatg cactcattaa aggaagaatg ccagatttct
    26881 ggtcaacaat tacgattccg caatcgcccc cacctgcacc agaagatttt gcggctcctt
    26941 catactgttc agctaaatta cacaatttgt tcaaagcagg cgtttcgatg acgaccccag
    27001 tgattgcaga taaatcatgc agtaattgtc ggttttttcg aatcatctgt tggatcaacg
    27061 ttacattatt ttctttaaac cctttgatca tttcgttgac acattctgta ctatttttta
    27121 agaaaagctg ataagccacc attttatctt ctctcgaacg gtgaacttga tcgaccaaat
    27181 cagaagtaga ggcagggcta cccgtccaac caatcaataa acgtaaatct tcaggagcaa
    27241 tcaatggctc aatggataga cctggccaat ccagggcaag taactcactg atagaatgct
    27301 gagtttcttg ttcttggagc caaggatggt cgaaggttga gaaagcgatc cagccaccat
    27361 aacagctagc agcgatgtcg ccgcaggaac cattatcttg aactgctaaa ttggctagtg
    27421 ctgcaatctt gaaaatctcc aactgagata aattcaacgc gtaaaaaaca ttcaaggctt
    27481 tgaccgttgc aacggtcacg gcaccgctag aacccaatcc atatttccgg ccatttgaac
    27541 tgtctaactc acttgttact ttcagatcat aaaaggataa aagaatgttt ttttcttgtg
    27601 catacttttc agtcaagcga atagcagcaa ggatataatg aaaaggattt tcccgaatat
    27661 ctaaaactaa ttctccgttg cgtcttgtcc aacgtacagg catcccacta tattgtgcag
    27721 attggatact tccgactttt cgtgcagatt ctacagtgac tgtcacgaat tgatcgactg
    27781 cagcgataac tgctggatgg cctgtttcaa caactgcata ttctccggca atatagagtt
    27841 tgcctggtgc agatacttca atcataaaaa tctcccttta ttcaataatc gcaattcctg
    27901 gaccagcatg tgcagtaatt acttgttctt tgctaaataa tttggtaaat gtttcttgta
    27961 cctcagataa atggctgttt tccactaaaa ctttgacatt agggccagca tccatcgtaa
    28021 agtagcatgg aatgccttgc tttctcaatt gtcgcaccgc atccatcgct tttaagctgt
    28081 caggagacca gtaagtgaat ggaggctggg cagctaaagt cgttccatgc atttttagtc
    28141 cgtttctttc catcgtttct ccgagaagtt ggaaatcttt tgttttgatt gcttgtttca
    28201 attgatatag atccccttca acggaatcta accagccttg ataaaaactg gatgtttcga
    28261 ctgtccgacg catcccattt ctgctggaca cttctttttt ctggtcgttg atcaaaacga
    28321 aaaccattgc taaatcgtct tcgaaagaat cggaagggac tggcttagcg taagaactta
    28381 agtcgtcatg gcctttttcc cattcgacga aaccaccgaa aatacttcgg caagctgaac
    28441 cagacccgcg tcgagcaaat cttgaaagag agagatcatc taatccaagc ttaagagcag
    28501 tattgcaagc gcctgctaaa gcagctagcc cgctggcaga ggaggctaat ccagctgcgg
    28561 taggaacgaa attctgactg attactgaag cttttagtga gaggccggct tctttacgaa
    28621 aaaggtcaag aaactgactg actttttttg ttgctttttc gtcttgcaag gtgccatcta
    28681 gataaaattc atctaccata tagctatcag aaaagatgac ttctgtctct gtataaaatg
    28741 catccaatgt taacgaaagg ctgttgttca ttggaaggat gagttcttca tttttcttac
    28801 cccaatattt gattagagca atgttggtat atgcgcgtgc tttgccttta aacataggta
    28861 tgtactccta atccttgtat ccaagtttca gcagcacccg catcttcaag tgcttgactg
    28921 atttcttggg cttttgtttt tgtttgtgct aatgcaatca tacagccacc gcgtccaccg
    28981 ccagttaatt tggcacccaa tgccccggta tcttttgctg tttggatcaa tagattaaga
    29041 aaatcattgc tgattgtcag cttttccaga agtgattgtg attcatccat tgtctgtgcc
    29101 aacgtttctg gtgaattttc aatgattgct tgttttgctt gcttcgtcaa gtatcctaat
    29161 ttttggatca tttgtccagt ttcatgaggc tgggtttcaa agaggtgagc gacatctttg
    29221 acggcttctc ttgtttgtcc tttgattcct gtatcagcga caatcaaaaa agcatcgatg
    29281 ttcaaagaaa agtagtcgaa aggatgccct tttgtaaaat aaatcggctg caagctgcta
    29341 gtagcggctg catcgattcc actaggatta ccgtgggcga ttttttccga aagctggaca
    29401 ttttctaata gtatttcacg agacaaagga aatgctaagt aatcataaaa agcacgagtg
    29461 actgctgtgg cgactgcagc gcttgatccc attccacgtt cagcaggaat cgtgctttca
    29521 atggtcagtt gcaagttttt ttggatgtca tgctgttttt ttaagtgaat gaataatttt
    29581 ttgatatttt ttaatgcatg aggagcttcg gctaaatttc ctgaatagta ggaagaaacc
    29641 agttgatcgt ccattgcatc cagctcttca aggaatgcgg tgacttttgt tgcatagaaa
    29701 ggaaaggcaa tcgctggttc tccataaaca accgcgtgct cgcccatcaa tatgatcttt
    29761 ccgcttgatt ctccttggcc atagtttgcc ataatctaac tccttctcac gtaaaagtga
    29821 tttttaagca aaaaataaag cgcccaaaac gagttgcgct gcttcacgaa tttttttgtc
    29881 cactaagggt ctcaaaaaac attcctcctt tattttacta aaaccatctc agaagtaaaa
    29941 ctaagaatac gttttctaaa gaaaaaacac ttttttctta agaatttttt gacttttttt
    30001 cttctttgac tagaaaaaaa tacaattgac actactagat attgggggta tatttaaaaa
    30061 ggttggagtt aaacacaata tttagtgatg aagtgagctg gaggtaaatg agcgtgatcg
    30121 ttttagcagg tacaattggt gccggaaaat caagtttaac agaaatgatg gctgaacact
    30181 ttgatagtca ggcattttat gaatcgattg atgataatga agtcttgccc ttattttatg
    30241 caaaccctga acagtatgct tttttgctgc aaatttattt tttgaataaa cgttttgcaa
    30301 gcatcaaaca agcaatgaaa gatgacaata atgtattgga ccgttcgatt tatgaagatt
    30361 cactgctttt ccatctaaat gcagatctag gaagagcaac agaaacagaa gttcgtgtgt
    30421 atgatgaact gctggaaaac atgatggaag aacttcccta tgctgcccat aaaaaacatc
    30481 cggatttatt agttcatatt cgtgtatctt ttgatacgat gttggagcgt atcgaaaaac
    30541 gtggtcgttc gtatgaacaa ttgtcctttg atccaagtct atacgattat tacaaagaat
    30601 tgaacagacg ttacgatcaa tggtatgaag aatacaaaga aagtccaaaa atccaaatcg
    30661 atggagaccg ctataatttt gtggaagatc ctcaagcaaa agaagaagtc ttgaaaatga
    30721 tcgaagaaaa attagcagag attcgccaaa ccaaagtagc catttgattt acagttgctc
    30781 aaataaaggg taaaccttta tttgagcgac ttttttcttt atactggaaa caaatgtcag
    30841 gaggatagag tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt tggatcaatg
    30901 tacagcaaaa cgatgtgcta gctgttaaaa acttaaaaga agaatatggc attagtgacg
    30961 agatgctgac ttattctcta gataaaaatg aacgggcgcg cgtagagtac gattcttttg
    31021 atgaagcgtt actgcttgta tcaaatgttc cgcaccagca aaaagtcgat aatcattatg
    31081 aaactagtcc tatcgctttt attttaaaag aagacggttt gtttacattt accacgccga
    31141 ataccgagta cgtgattcga ctaattcgat cgcttttgga acgaatgcca gacatgagtg
    31201 tatacagttt attgtttcgt acattgtttt tgatttctga ttcctttttt cctttaatcg
    31261 aggaagtgaa tagtgaacgt cagcggctta atctgaaatt aagagaaaaa acaacgaaca
    31321 agaatctgct gcaactttca gatttagaga tcggtttggt ttacttagtt acaggaacaa
    31381 aacaaaatgt agtactttta gaacaaatca aggcattggc tatttatcgc aagttgtcag
    31441 aaaaggaaaa agaagagttg gacgatgcgc tgatcgaagc acgacaagca gttgaaatga
    31501 cgaacttagc ttcgcagatt ttagaccagc tctctggcac ttataataat ttgctgaata
    31561 acaacttgaa tgacacgatg aaatttttga cggtctggtc gctgatcttg accgttccaa
    31621 ctattgtgac aggattcttc ggaatgaatc tccagttacc ctttacccat tccgttttcg
    31681 gatggggaat cgccttgatc atcagtttgg tcttatctat ttggatgctt attgcactgt
    31741 ggcggcggat tcgttgatct agtctttgat ctgcaaacca agggcttggg cgatcacaag
    31801 tgcttgctct tggttgacga ttagtcccgc caaagaatct tgagataaag cgattgctgt
    31861 gaagaaatta gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt tcgaaccggt
    31921 caactgattg tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt cgctgtcttc
    31981 taattgacaa tgatcgaagg agacagcttt caagtttgta ctactaaagg aagccatcga
    32041 agcaatacaa tcagtgaaag tacagtctcg aagataactt tcggcaaaat tcgtacctgt
    32101 taatttacat tgatgaaaca cgacttggtg gaaactgcca ccaatccact ccagattgga
    32161 aaaatcacat ttttcaaaaa tgacattact gcattcaaaa tgacgtaaaa ctgttttttg
    32221 catcgtaagt ttttggatat gactctctct taataccata tttttggcat cgagatagct
    32281 ttggtcaccc ccgttgatca gaagaccaga gaagatctcc tcatcttcta aataaaactc
    32341 tccctttgta agaagaggaa gagaaggtgg aataggttcg atttttttca tgtgggttca
    32401 cctcgttttt ctttagtata gcaaagaagc gggaatcact gctagaaagt ctgctaatct
    32461 aatcattttc agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa gattagtttt
    32521 tgctatacta tgatggttga gaaataaaag cagaagcacc cgcttctcgc cttagttgat
    32581 aatgtcactg ggctagatag ttttcactgg ttctattagg tgaagtacgc gcgggttctg
    32641 taagagaact cgttttttta ttgccgttta ttcggtaagc ttttctttct ctcataatat
    32701 ttggaggtga atgaccatag caaaggatat gatggttaac gacggcattc gtgcacgaga
    32761 gttacgattg atcggttcag atggtgagca attaggagtt aagacaaaag cagaagcatt
    32821 gaatattgca gaacaagcaa acttggatct tgtgttagtt gcccctggtg cgaaaccacc
    32881 agttgcgcga atcatggact acggtaaata ccgtttcgaa caacaaaaga aagaccgcga
    32941 agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc ctacgatcga
    33001 cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa agggcgataa
    33061 agtgaaagct tctatccgtt tcaaaggccg tgccattacc cataaagaaa ttggtcaaaa
    33121 agtcttgaat cgcttagctg aagaaactgc ggatattgca acagtggaac aaaaagcgaa
    33181 aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta agtaatttga
    33241 atgactaact ggctgttgga cagccgatag tcggataacg aaagattttg aggaggaaat
    33301 atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa acgtactggt
    33361 aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg caaaacaaaa
    33421 aaacaacgcc gtcaattgcg taaagcaagc atggtttcta gtggcgactt caaacgtatt
    33481 cgccaacaac tagcaaaaat gaaataagaa gtacaaataa cagaatctga agatttattt
    33541 ttattaggag gaattataca tggcacgtgt taaaggtgga acagtaactc gtaaacgtcg
    33601 taaaagagtg ctaaaattag caaaaggtta ctacggttca aaacacactt tatttaaaac
    33661 agcaaaagaa caagtaatga attcatacaa ctacgcatat cgcgatcgtc gtcaaaagaa
    33721 acgcgacttc cgtaaattgt ggattgctcg tatcaacgca gcagctcgta tgaatggctt
    33781 gagctactca aaattaatgc acggtttgaa agttgctgaa atcgacatca accgtaaaat
    33841 gttagctgac ttggctgtta acgatgcagc agcatttact gcattggctg accaagcaaa
    33901 agaagctttg gctaaataag ctaaacaatt ataaagagga aagaagataa cgaaaagtta
    33961 tgttctttcc tcttttttta tttacaatcc tccatcaaat gaaacaggac aataacgtat
    34021 aagtctaaaa tagcataatt aaggtttttt aattgaaaac tgaacattta tggtcaccct
    34081 ttaatgaaag cgctaactac ataagttaga atgagtttga ctgatatatt agtttgctta
    34141 tcagaaaaac aaaatggacg gaggaataac atgagtgata ttattattgg tattttgtta
    34201 gttatctcat tctttttcat ggtctggtac tgtgtaaaag gctacaactt gatggtcggc
    34261 tttgccatca tggctactgt atggatggga ttagcgctag tcggaaacac gttttcacca
    34321 aacccggcga tggaagggca aggagtaatt gatgtgttga cgcatatcta tacgacgggg
    34381 ccagctgagt acgccaaatc gatcttggta aatgtcttct ttggtgcctt tttcgggcgt
    34441 gttctagtag atagcggaat cgcagctacc ctgattcgaa aggtagttga acttggaggg
    34501 gacaagccaa gaatcacgat gagcttacta tgtattgtaa ccgctgttat attcatgtcg
    34561 atgacaggaa tcggaccagt gatttctatt gcagttattg tgttgccaat cttgatgtca
    34621 ttaggtattt cagtaccggt tgcactgttc tcatttatgg gctcgattat ggctggaatc
    34681 tttgctaata tcgtcaattt caaacaatat caaacgattt atgctggttt caatccagcg
    34741 gctgaaagct atacttataa tgactatttc caaattggta tgattgggat gattgtaagc
    34801 ttagttgtgg tactaacggt cgctaatata tcaatgaaca aaaagaaacg ctatgcaatg
    34861 gcagcaaacg taccagctga aggtggcgac gcaccaatga tctcatggtt agccgtatta
    34921 ttaccagttt taggggtcgt tcttttagat cttccaatca tcttaggttt tattctagca
    34981 ggtatctggg cattgctgtt tactggaaaa ttgcgcggag gttataaaga aatctgtcgt
    35041 cagtttgcga aattatttac agatggcgca gtagatgttg caccaatggt tggtttcttg
    35101 atgaccttag cgatgttcaa taattcagct gcgtatgctt ctccttattt ttcagctatt
    35161 tttggagatt ggataccgca atcaccatta gtcttggcaa tcgtatttgc tatattgaca
    35221 ccactaggat ttttccgcgg tccaatgaat ctagtcggtt caggctcagc tattttagct
    35281 gtcgtattag ctgttaatcc aacgatgtcg ccagcctttt tgttcccgtt atttgcaatc
    35341 acaacgattg ctcctcagca tttagatatt acacaatctt gggttgcttg gggattaggt
    35401 tatacaaaag taacttctcg agaatatatg aagaaatcca tcccaactgg ttggatcatc
    35461 ggagcgatct tatgcctgat cacgttctta ttgtacggga acgcctagta aacaaaacgt
    35521 cgataaaaac gattagatga atggaggaaa agaaaatgaa acgttttgtg cgaatgggaa
    35581 ttgatgttgg cggtacacat acgaaagcag tcgcaatcga taatgcgacg cacgaaatca
    35641 tcggaaaatc ttcagtgaaa acaacccacg atgatgtccg tggagtagcc gcaggtgtcg
    35701 ttcagtcttt tcaaaattgt ttgcgggaaa ataatatcag tccagaagat gttgtgtttg
    35761 ttgcacattc taccacacaa gcgactaatg cactgattga aggagacgta gcaaaagtcg
    35821 gcgtaatcgg gatggcaaaa ggtggattag aaggtttttt agcaaaacga caaactagat
    35881 tgaacgatat cgatttaggg aataagaaaa aaatagagat tgtcaatgca ttcttacctg
    35941 tcaaacactt aaatgtagac cgtgtttcag aaacgatttc ttctttagaa agagaaagag
    36001 cggaggtctt ggtttcttct atggcatttg gagtagataa tggggaacca gaacgagttg
    36061 tttatgaagc agcatcggta aaatcgatcc ctacaacgat ggcttctgac atcacaaaat
    36121 tatatggatt gacaagaaga actcggacag cagcaatcaa tgcatctatt ttaccaaaaa
    36181 tgctagatac ggcaacctct acagaagatt ccgtacgaga agcaggggtc aatgtttctt
    36241 tgatgattat gcgcggagac ggcggagtaa tggaaatcaa tgaaatgaaa aaacgacctg
    36301 ttttaaccat gctttccggt ccagcagcat cagtcatggg ctctttgatg tacttgagag
    36361 cgtctaatgg tgtttatttt gaagtaggcg gaacaacaac caatatcggg gtcattaaaa
    36421 atggacgtcc agcaatcgat tattcaattg taggtggcca cccaacatat atctcttcat
    36481 tagatgttcg ggttctaggt gtggcaggcg gttcgatggt acgggctaat cagtcaggaa
    36541 tcatcgatgt cggtccacgt tctgcacata ttgccggtct agattatgca gtatttacgg
    36601 agacagaaaa aatcaaaggt cctaaggttg aatttttctc tcctaaagaa ggagaccctg
    36661 ctgattacgt caaggtagtg atggaagacg gagaagaagt gactattaca aatacatgtg
    36721 cagccaatgt ccttggatta gtgcaagaag aacatttttc ttatggaaat gtcccatctg
    36781 cacgaaaagc catccaagca ttagctgatt attgtcatac gacggttgaa gacatcgcag
    36841 aacagatcat ggaaaaatcc tatgctaaga ttgaaccggt gattttagaa ttggcagaca
    36901 agtatcactt ggagaaagat cagatttctc ttgtaggtgt agggggcggc gctgcctcat
    36961 tgattactta ctttagtaat aaaatgggtg tgaaatattc gattcctgaa aacgccgaag
    37021 tgatttcttc tattggtgta gcacttgcaa tggtccgaga tgttgtagaa cgtatcatcc
    37081 cttcgccaag taaagaagat atacgatcgt tgaaaaatga agcgatgaat aaagcgattg
    37141 aatcaggcgc tacaccagaa tcgatcgaag tccacgtaga aatcgatcca cagacttcaa
    37201 aagtaacggc tatcgctact ggttctacgg aagtgaaagc aaccgatcta accaaggaga
    37261 tcacaacaga agaagcacta gagcttgctg cagaggatat gcgattaaat aaaaatgaag
    37321 tttgcttatt ggaaaataca cctttctttt atgtatgcgg cgaacagaat cgttcaaaaa
    37381 atgctggaag tcttcggatc atcgatcaaa aaggatttat caaggtccaa cgtggacatg
    37441 cttcatgtat gaaaacaact gcagccaatt atatgacagc tgtcgaacaa ctttgggaag
    37501 atatggcagt ttatcaaact gaattgattg cccgaccaga attttatctc tgcttaggag
    37561 caagagtctc tgattttaca gcgacggatc tggaacaact acagcttttg atggatctgg
    37621 aagtatctac tatggaaccg gaggaagaag tgatcgtcgt tgccggaaat atcaaacaaa
    37681 cataagttag aagagttact aaacgaatta caacagatcc ccgaagaaat ttggggattc
    37741 taccagtttc ggcgagattt attttggaaa aagattcctt tgtccaagca gaaaattctt
    37801 atacaacaat caatcgattg tggtatcgaa acggcatgta gcatcaaaaa aaagtaccct
    37861 tttgccgatg taggagaaat ttgtgaacaa atggctgttc caatcgtttc ctgtgaatca
    37921 gagcaaataa acgaacgaat cacttttgca acttatgcag aagatgaagg gattcgattg
    37981 atgacggagc cgttagaaaa attaaaatgt tcaggactag cttcgatctc taaagaaaca
    38041 gcgcaagctt tgattattgg acatgaacta tttcaccaca tcgaagcttc tgttaaggga
    38101 atttatacgc aaagcgaaaa aattgtgctg tggcggttgc ctttttatac acatcaatca
    38161 aacattcgtg cattgagcga gatagcagcg atgagttttt caaaagagat gaatcaaagc
    38221 gatttttcgc cttatgtatt agaggcagtc ttactttggc catataatga aattcgtagc
    38281 caagggatct tagaagaaat aaaaaaaata gaaaaaagat gtacggagta tgatttagat
    38341 tacaaataaa gagactgtga caaaagtcgt gtcacagtcc tttttttccg aataaacgat
    38401 gttctcctgt caactcctcg gtcacaagtc aaaatattca acaaacatga gaagctgttt
    38461 tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc ttggaaaacg
    38521 gtgttcaaaa gcttgcatct gcggtaataa gtccagccaa gttaaaaaca taagaagcta
    38581 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctctcaataa
    38641 acggtgtgca atcagctgac cctcggtatt agctcaaaaa aaacggcaaa atatgaggaa
    38701 ctattttgcc gtttctttct ctaatactca ggtcaaaacg ctgattccaa aacctcttat
    38761 ttgatgggtc tgtcctgaat atcttcaaaa taatcggggt aattatgaat cacgtattct
    38821 tgctcctcga taatcatatg taaatgcatc gtgcaaagaa atccgacttc atcaaagtta
    38881 tgatcaatca ttgattgaag cattgtctga tgttcatcta atactcgacc ccagtctaat
    38941 tctgaaatcg tcaaacgtaa ccatctgaaa cggttcaagt gcgtactata actttctagc
    39001 caatcccaaa tttctcgttt tccagcaatt tcataacaag ttcggtgaaa atcagtatcc
    39061 aaatcaaaaa aagctttttt attttgagcg attactgcct gatcggtttt tccaactttt
    39121 cccgcgtata acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg
    39181 actgtggaat ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg
    39241 gtgtacgccc gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg
    39301 ctaactcgga ataaatgatt tgtttacgta tagattcata agcttgctgt tgcaaattat
    39361 tgataaccat ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta
    39421 caaatcgtgt gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta
    39481 gagcctcgaa aagaaaaata ttgaatcaat ctggtcgtac ctcttgtatc ggtttgacac
    39541 gaccgccgat tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat
    39601 tgtctaagtt tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt
    39661 taacgacata catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca
    39721 atacaagaaa aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac
    39781 gcttggaata actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa
    39841 tcagaaagta aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt
    39901 cccacaattt cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg
    39961 atgctcactt tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg
    40021 gggatgatga tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag
    40081 gctacccgag cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga
    40141 tctgtttcat aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc
    40201 tcgttttcca ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt
    40261 tgtgtcggca aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga
    40321 taaatagctg ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc
    40381 atcccagcta aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg
    40441 gtgtagaagt gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca
    40501 ccgatttcct gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa
    40561 ctcaaccgtt gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc
    40621 aaaagatgat tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct
    40681 tttgattggt tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat
    40741 ccgggaccaa tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc
    40801 gtccaaacta caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca
    40861 tcagttacta cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg
    40921 attgctccgc catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta
    40981 tgtgaaattt ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc
    41041 taaaaacctc cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa
    41101 aggaattgtc agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa
    41161 gacttaaata agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca
    41221 cgtaaagaag acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat
    41281 gactcaaaag taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat
    41341 atgttagctt atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg
    41401 catattgatc ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt
    41461 cctgcaggag atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc
    41521 tttgcacgcg gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag
    41581 atcattaaag aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat
    41641 gaagaaagcg gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt
    41701 ggtttctcac cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta
    41761 gctttacgct tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga
    41821 cttcgcgaaa atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat
    41881 gcagctatcg cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga
    41941 acgattgaag cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt
    42001 gcaagcccac aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat
    42061 gaattcctag gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat
    42121 ttttatggag aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg
    42181 aatgctggac tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg
    42241 aatttccgtt ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca
    42301 gtggggcaag aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta
    42361 ccaatggatg atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa
    42421 aaaggctacg aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt
    42481 gcttatggag cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg
    42541 agtcttgatg acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg
    42601 aaataattaa ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt
    42661 ttttactttc tactgtggta ttcatgataa acatgatata gattcaattc atattctttc
    42721 ttagcgttcg tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa
    42781 gtcatcaatc cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata
    42841 tattcgcgaa tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa
    42901 atcccaaaga aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact
    42961 ttgaatccgt cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa
    43021 tcgattggga tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt
    43081 tcgatttgaa aaccagaact cataatagga aaacttttga caaagatacg attgaatcct
    43141 cgatagccgg tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta
    43201 acaaggttat ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt
    43261 gataggcgat caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca
    43321 tgtacagctt ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg
    43381 atatcaaaga acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg
    43441 attgctccac cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca
    43501 taaatatctg cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct
    43561 tcctcattgt aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct
    43621 ccttaactat agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag
    43681 tttttcccgc taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc
    43741 tctatctaaa aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg
    43801 gtgcgtattc gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa
    43861 atttctaata cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca
    43921 tcttctattc gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata
    43981 ggttcctttt caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac
    44041 ttgatatttt caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt
    44101 gaagctaccc cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag
    44161 cttagttcgc tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg
    44221 tgcttatttt accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat
    44281 aagctataat aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat
    44341 aagtctgaga ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt
    44401 caacgaatca aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc
    44461 gcttatatgg aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc
    44521 ggcatttttg gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca
    44581 catatggatg aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc
    44641 gtacctctag gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc
    44701 tctactggta agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga
    44761 acaagcggac aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca
    44821 agagaagagg caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa
    44881 acgatcaaaa cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc
    44941 tgtacaatgg tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg
    45001 attgcaggcg cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat
    45061 aaattcaagc cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg
    45121 aaaaatggca cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt
    45181 ttgatcatgc ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc
    45241 ccttatcaat actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac
    45301 gaaggaatcc caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg
    45361 atgttcagta ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt
    45421 ttggataaat caacagtgaa tacgatcgta tacggaaaat aatgcgatag tgaaactata
    45481 aaatctggca aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg
    45541 ttagttcgaa agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac
    45601 aaagaatgat tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga
    45661 gtgtattttt ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc
    45721 ctgaaattga aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca
    45781 tagatgtagc cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg
    45841 gaaaagaatt aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt
    45901 tcctagaaag tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat
    45961 ataagaatat tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag
    46021 cggtagaagt ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc
    46081 aattttataa ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg
    46141 aaacagccaa ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa
    46201 atatagaagg aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa
    46261 aaaaatatga gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct
    46321 ttatgacagg aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg
    46381 tttctgacga agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa
    46441 tcaattaact aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg
    46501 aataaatggt gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca
    46561 gtgaatgcaa ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga
    46621 tttttgctta taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata
    46681 aaggaacaga aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag
    46741 gtcaagttgt tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg
    46801 gccaagtaag cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag
    46861 gattcgaaga acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa
    46921 catgcgtccc acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg
    46981 gtacagtatt gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg
    47041 ttgcaaaacc aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag
    47101 gggtagatag ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag
    47161 caaaaaaagg aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat
    47221 aaagaggttg tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat
    47281 tttgttttaa tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc
    47341 cttcatagta agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa
    47401 gttctacacc agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca
    47461 atccagcttt ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta
    47521 cagatgaagg aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga
    47581 ccattgtgat acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga
    47641 tattcactac atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag
    47701 tagattcaga agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat
    47761 taactaaagg accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga
    47821 tattgactgt ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga
    47881 ttcctgaagt gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag
    47941 gctcaccaac cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg
    48001 aattgatctt caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta
    48061 ccttcgtacc gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat
    48121 tcgtgactac ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat
    48181 aagcttccaa attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc
    48241 caaaaccgct tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa
    48301 ctttatctac cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg
    48361 tttcaccggc agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca
    48421 tcgctgcata aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca
    48481 gacctaactt acgccagagg ctattatttt tacttttttt catctttggt gtcacatttt
    48541 ttctatccat gtgttcctcc tccaattaca ttcatttatc tactgttagt atagtcttat
    48601 ttgttgactt tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaatc
    48661 attgttttca gatgaaaata tttgattttc tttttccaca gatactgtgt aaaactacgc
    48721 ggataggatt ggaaaaataa gggataaaac atatccacag cctgtgtata aagtggataa
    48781 attcttataa aacgtatgtt tgcctaatga atgtgatgaa ataaggtaaa ataacactgt
    48841 tttctgtgga taaacctgtg gatgttgtgc ataactgttg gggaaatctt tttaacaaaa
    48901 atagccaaaa taaacatata gacgaaaaaa ttgattataa taaacaaagt gagcatgaag
    48961 accaaaggag agaaaacatg aatatcaaaa ttatctcagt aggaaaatta aaagaaaaat
    49021 acctgatcca aggtatcaat gagtatgtca aacggctgaa tgcctatgca aaaatcgaat
    49081 tgatcgaagt tcctgacgaa aaagccccgg agaatttaag cgaagcgcaa atgagacaag
    49141 taaaagaaaa agaaggggaa cggatcttag cgaaaatcaa agaacaagaa tacgtctatg
    49201 ccttagcaat tgaagggaaa aatcctacaa gtgaatcttt tgctaaacaa atcgaccaat
    49261 taggtatcca aggaaaaagc caccttgttt ttgttatcgg cggctcttta ggactcagcg
    49321 aagccgtcat gaaaagaagc aatgctcaga tctcttttgg aaaaatgacg tatccacatc
    49381 aattgatgcg tctgatcctt gtcgagcaaa tctaccgtgc cttccggatc aatgcggggg
    49441 cgccttatca taagtgatgc ggtttttatc attgatccta aaaatcttag caagacaaaa
    49501 agtacgtaag aaagtaaaga ctaaatactt cggaggaaca aatgaataac aatgataggt
    49561 tattgcgatt gcgttatgcg attgatttga aagatacgga tttgattaaa gcttttgagc
    49621 taggcggtgt accactgact aaagaagaag ctcaggcggt actgaccaaa gtacaggata
    49681 agaacaaaga taatgcagaa aataatgtgt atgaaaaaac catcaacaac caagtttttg
    49741 acgcattcct aaatggcctg attctcttgg cgcgtggtcc gcaaaaagat aagccgatag
    49801 tagacacgcc gcaaaaaagc aaggaaatca aatatatcaa caatgtgttg ctaaaaaaat
    49861 taaaaatcgc cttgtctatg accactgatg atattttaga cgtttttgct gaggcagaaa
    49921 tctatccatc aaaaggcgaa atcggggcat ttttgagaaa agaaggccaa cgaaatttta
    49981 agccttgcgg agataaatat atgcgtaatt ttctcaaggg gttaggaatt tataatcgga
    50041 gaaaagtata aagaaatttc atgagaaatc aaaacaatgg ttgttttgat gagagctagt
    50101 ttttgtatga gattaaaata ttatcttaat cgaggagctg gattggtttt atgaatgatg
    50161 aatataagaa tgatgaagat aagatgcttt ttgaagagat agagaatcga tgtaggctca
    50221 attttgagct tcggggaaag atgtctttaa tacaacaaaa aaagtattta gcgaataaat
    50281 cagagtttac tctgggacat gttgaaaaat taatctcgga ttggattagt agtagaagcg
    50341 aatttacaaa aataaaacag ccgattaaat ttgacatgaa aaaacttttg ttaaataaga
    50401 gtgagatagg taatagagat caatatatta gagctaaagg gcaagaaata attgattcat
    50461 taggtgaaat gaggtcatac aattatttgt atgtaacaca tagagctgat ggaatggtca
    50521 ttactgtggg gaaatcttct tctaatgata tttttttaga tggagatctt ttttatcaac
    50581 tcaatacaaa tcacttgtct ggcactgaaa atataatttt aaggacggaa tatggcaatg
    50641 aaatatttgc aaaatatgat gagattttaa aaaattattt ggactgggct tggataattc
    50701 cggttgagtc aggagatgct aagaaactgg agagattatt gggcgatgaa ctaattaata
    50761 aaaaagtacc aattttaaat tattattccc atagacaata aaaggctatt tttcatgata
    50821 atactagtta taactgtaaa aatggaagaa aatctgggaa agaagt
//
LOCUS       DAIGWC010000011        49995 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.011, whole genome shotgun sequence.
ACCESSION   DAIGWC010000011 DAIGWC010000000
VERSION     DAIGWC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.011"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..1008)
                     /locus_tag="NOB74_000672"
     CDS             complement(<1..1008)
                     /locus_tag="NOB74_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI1219879.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="NOB74_000673"
     CDS             complement(1188..1532)
                     /locus_tag="NOB74_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCI1219880.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="NOB74_000674"
     CDS             complement(1525..1959)
                     /locus_tag="NOB74_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HCI1219881.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="NOB74_000675"
     CDS             2097..2834
                     /locus_tag="NOB74_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1219882.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="NOB74_000676"
     CDS             2827..4038
                     /locus_tag="NOB74_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1219883.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4242..5024
                     /locus_tag="NOB74_000677"
     CDS             4242..5024
                     /locus_tag="NOB74_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HCI1219884.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="NOB74_000678"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="NOB74_000678"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HCI1219885.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="NOB74_000679"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="NOB74_000679"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HCI1219886.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="tadA"
                     /locus_tag="NOB74_000680"
     CDS             7740..8669
                     /gene="tadA"
                     /locus_tag="NOB74_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HCI1219887.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="NOB74_000681"
     CDS             8626..9675
                     /locus_tag="NOB74_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HCI1219888.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="NOB74_000682"
     CDS             9672..9950
                     /locus_tag="NOB74_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCI1219889.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="NOB74_000683"
     CDS             9925..10395
                     /locus_tag="NOB74_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HCI1219890.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="NOB74_000684"
     CDS             10412..10714
                     /locus_tag="NOB74_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219891.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="NOB74_000685"
     CDS             10731..11102
                     /locus_tag="NOB74_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HCI1219892.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="NOB74_000686"
     CDS             11074..11433
                     /locus_tag="NOB74_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219893.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="NOB74_000687"
     CDS             11605..12612
                     /locus_tag="NOB74_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1219894.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="NOB74_000688"
     CDS             12637..13821
                     /locus_tag="NOB74_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HCI1219895.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="NOB74_000689"
     CDS             complement(14258..15841)
                     /locus_tag="NOB74_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI1219896.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="NOB74_000690"
     CDS             complement(16419..16562)
                     /locus_tag="NOB74_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HCI1219897.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="NOB74_000691"
     CDS             complement(16785..17264)
                     /locus_tag="NOB74_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI1219898.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="NOB74_000692"
     CDS             complement(17337..17621)
                     /locus_tag="NOB74_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219899.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="NOB74_000693"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="NOB74_000693"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="NOB74_000694"
     CDS             complement(17965..19251)
                     /locus_tag="NOB74_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HCI1219900.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="NOB74_000695"
     CDS             19389..20060
                     /locus_tag="NOB74_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HCI1219901.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="NOB74_000696"
     CDS             20026..20514
                     /locus_tag="NOB74_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HCI1219902.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="NOB74_000697"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="NOB74_000697"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HCI1219903.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="NOB74_000698"
     CDS             21475..22239
                     /locus_tag="NOB74_000698"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HCI1219904.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="NOB74_000699"
     CDS             22472..24685
                     /locus_tag="NOB74_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HCI1219905.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="NOB74_000700"
     CDS             24696..25142
                     /locus_tag="NOB74_000700"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HCI1219906.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="NOB74_000701"
     CDS             25313..26572
                     /locus_tag="NOB74_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HCI1219907.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="NOB74_000702"
     CDS             complement(26661..27608)
                     /locus_tag="NOB74_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI1219908.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="NOB74_000703"
     CDS             28002..29294
                     /locus_tag="NOB74_000703"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HCI1219909.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="NOB74_000704"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="NOB74_000704"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HCI1219910.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="NOB74_000705"
     CDS             31187..32062
                     /locus_tag="NOB74_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1219911.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="NOB74_000706"
     CDS             32328..34211
                     /locus_tag="NOB74_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCI1219912.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="NOB74_000707"
     CDS             complement(34286..34570)
                     /locus_tag="NOB74_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCI1219913.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="NOB74_000708"
     CDS             complement(34560..35294)
                     /locus_tag="NOB74_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HCI1219914.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="NOB74_000709"
     CDS             35423..36046
                     /locus_tag="NOB74_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HCI1219915.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="NOB74_000710"
     CDS             36238..37359
                     /locus_tag="NOB74_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HCI1219916.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="NOB74_000711"
     CDS             37366..40494
                     /locus_tag="NOB74_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HCI1219917.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="NOB74_000712"
     CDS             40513..43707
                     /locus_tag="NOB74_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HCI1219918.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="NOB74_000713"
     CDS             complement(43853..44560)
                     /locus_tag="NOB74_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI1219919.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            45325..45723
                     /gene="spxA"
                     /locus_tag="NOB74_000714"
     CDS             45325..45723
                     /gene="spxA"
                     /locus_tag="NOB74_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCI1219920.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            46055..46708
                     /locus_tag="NOB74_000715"
     CDS             46055..46708
                     /locus_tag="NOB74_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HCI1219921.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            46934..47932
                     /locus_tag="NOB74_000716"
     CDS             46934..47932
                     /locus_tag="NOB74_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HCI1219922.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            48108..49916
                     /gene="pepF"
                     /locus_tag="NOB74_000717"
     CDS             48108..49916
                     /gene="pepF"
                     /locus_tag="NOB74_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HCI1219923.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        16175 a         8741 c        10455 g        14624 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaacta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgatcgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggc
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagct agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 ttattttttt aatacagtct caatataact attcaaacat aaaataacgt tatttgattt
    44881 atttgtttat agtaaatttt atttagtaat cattgcttta aaatactacg cttatataac
    44941 agagaaaata agcgttataa taaagaacag tattatttaa aatgacagaa aacattacta
    45001 ttaaagaaat aaaaaacata aaaaatctta agaaatcggt ttcatttagc ttttgagata
    45061 aaataatagt acagttttat acgctgtttc atatgtttag aaaatttgaa ttagatttga
    45121 aaactctaat ttttaaatga taaaaaaagc gagaatgctg gttttactgt atattaacct
    45181 tagataactt tcattttttt aaaaaaatta tgaaaaaaag gtagctattt aaaagttgat
    45241 tatgtataat agaaacagat gggagattat tatgatcttc tgttacaaaa aagtgattct
    45301 tatcacgaaa aggagtggtg cacgttgtta acattatata cttccccaag ttgtacttcc
    45361 tgcagaaagg ctcgtgcgtg gttgcaagaa catcagattc catttgttga acgtaatatt
    45421 ttttcagaac cattgaacag ttctgaatta aaagcgattt tacaaatgac agaagacgga
    45481 acagaagaaa tcatctcgac acgttccaaa gtattccaaa aactgaacat ggatttagat
    45541 gatctgccgt tacaagaatt attggaactt gtgcaaaaca atcctggatt gcttcgccgt
    45601 ccaatcatga ttgatgataa acgtctgcaa gttggtttta atgaagatga aattcgtcgg
    45661 ttcctaccgc gcgatgtacg acaattagaa ttacgtcaag cacaattgat ggctggatta
    45721 tagaaggata atacgaaact tggaaaagac tattacaaag atagtttttc caagtttttt
    45781 tgtttttaca aaaagtattc ttgattagat gtataaaaag gtagtagaag atgatgattg
    45841 cacgaaaaat agagagggaa aattagctga aaagtcggct atatagtatt cgtctgccaa
    45901 aaatgttata gttaaataag atagcttgaa aggttgaaaa atccgctggt tttattaaat
    45961 tcgcttaaca gcgagatttt ttttctttac atttaagctg atttcgctac aatgaatcta
    46021 tattaaacat tgtggcaaag tgaggtgtag caaaatggaa atggaacata ttaatgaaaa
    46081 tacgatccgt gtactaattg gtcatgaaga tttagaggaa cggggcgttt catttttgga
    46141 tttacttggc aatcacaaag aaatcgaaaa tttcttttat agtattttgg aagaagttga
    46201 tatcgaagag gagttccgag gaagcgaagc tgtcactttc caagttttgc caaaaggaga
    46261 cggattagaa ctgtttatca gtaaaaatct tccggatgaa gaaatttctc aatcagaaga
    46321 ttctactgtt gattcagaag atgtgagtga ctttcttcgt cagcagatta ttggcagcga
    46381 tccggaggaa gaattatctg gaagcgccct agaagaacag gaaagacaag caacttttgc
    46441 ttttgaagat tttgaacaag tgatccaact tgcaacagat gtcgaactag agtctgcttg
    46501 gactgatttg tatttattcg aagagcgcta ttacctagtc gttcacttct ggatggaaaa
    46561 tctcaaccaa gcggatgtag agaatcagat tgctcgaatt ttggagtttg ctgaaaagag
    46621 cgatcgtaca ccagaaacat tgaatgaata tggacaatgt ctgatggcgc gtaatgctat
    46681 cgagcgaacg aaattttatt ttgtataaat cagcattata gtaagagact gtgacaaaaa
    46741 ttgtgtcgca gtcttttttt cgtataaatg tgttcaaaag cttgcatctg cggtaacaag
    46801 cccaaccaaa cgaaaaatat tgggaactat ttttgtttag ctgttcttat tacttgatgc
    46861 agaatagctt tttcacgccc tcttttttcg tgtaaataaa ttcttagacg taaataagtt
    46921 cagagggaga aaaatgctgc ttgcaatgaa tgaatataat aagtgctgtt ttgctaaaca
    46981 tgcagaaaaa ggaaagaaat attattgtcg tggctgtcga aaaagagtga ttttgaaaaa
    47041 gggaaagaaa aaatgtgctc attttgccca tcaaaaatca gataactgtt cggtctttag
    47101 tgaaagagaa tcaaaagagc acttacagtt aaaggaatgc ttcatggatt ggctgggaca
    47161 gtcagtagaa ccagtatttt tggaagccta tttgccgagg ttgcggcaaa ggccggatat
    47221 tttgttggcg aatctagcaa tagaaatcca atgttctaga ctgtctcacc agagatttat
    47281 tgaaagaacc caaaattatt tgaataacag ttaccaagta tggtggatac ttggtaattc
    47341 ttttcttgga caatcgcaat tctcattgat agaaaaaagt tgctgctact ataatagaaa
    47401 aagaggagtg cattgctgga aagctgatct caagaaacaa aagctttatt tgtatcatca
    47461 tattacagag actgtatcag ggcatatttc cttttgcagt agctgctgga ctttttctag
    47521 tagggacctt aaagaaatat tcactagtaa cgaaattaaa atgaaccaaa tgaaaaaaat
    47581 agaaaaagtg agtgaagatg ggaagaaatg gctgacacgc caacttattc acaagcaaaa
    47641 gaatacagta tccatacaag aacaatgcta cttgcgtcat aaacatcttt tgcatctatc
    47701 atcgtggatc tatcaaaaaa gtcggttttt cttttattta caagaacagg tttttcttta
    47761 tcgaatgttg tacgaagaag ccttggaaaa ccagaaagtt cctgatttca actcatggct
    47821 ttgccaaata aaagaacata aaagggaatg gctttttcct atgattgatg aagagatggt
    47881 ctatcagcag ttttttaacg aatgcataca cttgtcttct ttgaaaaaat agtaagtata
    47941 aaaataggct aggaatcggt tttctatgta aaacaagatt tagttatgct aaaattgatg
    48001 gaagcagaca catgaatgag tagaaaagtt agatgctgtg acatgtggat gttagactat
    48061 gatctatttt gatagataga gctaagggaa gaaaaggagt ggatttcatg gaagtaaagc
    48121 agttgccaaa acgagaagaa ttgcctgaaa atttaacttg ggacttgacc aagatctttt
    48181 caagcgacca agagtttgat gagaaatatt tggaattatc agaagagtta aaacaatctg
    48241 aaaaacacaa aggaacactt gatcaaggcg cttctcaatt tttaaatgcg attgaattcg
    48301 tattgagggt ttatcgccaa actgaagtca tttatgtata tgcgcacctt aaaaacgatc
    48361 aagacactgg aaatacagat taccaagcgc tttatgcaag agcaagcagt ctgttttcga
    48421 aagttagtga agccgtttcc tggtttgaac cagaaatatt gcaattgtca gatgaccaga
    48481 tttggcaata tttcaaagaa gaaccaaaat tggaagtcta tcgccattat atccagcaaa
    48541 tagtagataa tcgagcccat gtcttatctg ctgagcagga atctcttctt gctggagcag
    48601 gtgaaatctt tgatgcttca agtgatacat ttgctgtttt gaataatgca gatctagttt
    48661 ttccaacgat tgaaggagaa aatggtgaaa tagtccaatt atctcatggc gtgtatggtc
    48721 agttgctaga aagcacggat cgaagggtgc gcgaagcagc atttaagggg ttgtacagtg
    48781 tttacgaaca atttagaaat acatttgctt ctactttagg cacacatata aaaggacata
    48841 attttaaagc gaaagtccgt aattacagct ctgccagaga agcgtctttg agcaataatc
    48901 atattcctga aagtgtatac gatactttgg tagacgtggt aaacaagcat ttgcctttgt
    48961 tacatcgata catggaatta cggaaacgtt tattagaagt ggaaaaactg cacatgtatg
    49021 atctttatac accggtctta ggggaagctc caattacctt tacgtacgaa gaagcaaaag
    49081 aaaaagcttt agaagcactg aaaccaatgg gtgaagaata catggccatc gtagaaaaag
    49141 cattctctga acgttggatc gatgttgtcg aaaataaagg gaaacgaagc ggtgcttatt
    49201 cttcgggaag ctatgacaca aatccatata ttttattgaa ttggcatgat acgctggatc
    49261 agctatttac gcttgtccac gaaatgggac atagtgttca tagttatttc actcgttcga
    49321 accagcctta tgtgtacggc gactactcca tctttttagc agaaattgct tcgacaacga
    49381 atgaaaatat cctaacggag tatttattgg aaacagaaaa agaccctcgt gtacgggctt
    49441 atgtactcaa ccattacttg gatgggttta aaggaacagt tttccgccag acacaattcg
    49501 ctgaattcga gcatttcatg catacggaag atgaaaaagg tgtgccattg actagtgaat
    49561 acctaagtga tagttatggt aaattgaatg caaaatatta tggtccagca gtcgaagaag
    49621 acccagaaat taaattcgaa tggtcacgga taccgcattt ttattataat tactatgttt
    49681 tccaatactc gactggcttt tctgctgctt cagcactggc gaagaaaata ctaaaccagg
    49741 aaccagaggc actagagaac tacttggctt acctaaaagc aggtaacagc gattatcctg
    49801 tggaagtaat gaaaaaagca ggagttgata tgacacaggc tgcatatatt gaagatgcaa
    49861 tgtcgatgtt tgaacaacgt ctaaatgaat tagaagaatt gatcgatcgt ttataaggct
    49921 ttctattttt gattttctcg aatagaaacg aaaaaaatac gtcggctctc ttgtaaggga
    49981 gtcgacgtat ttttt
//
LOCUS       DAIGWC010000012        47222 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.012, whole genome shotgun sequence.
ACCESSION   DAIGWC010000012 DAIGWC010000000
VERSION     DAIGWC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.012"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(27..1259)
                     /locus_tag="NOB74_000718"
     CDS             complement(27..1259)
                     /locus_tag="NOB74_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HCI1219924.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1514..2083
                     /locus_tag="NOB74_000719"
     CDS             1514..2083
                     /locus_tag="NOB74_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1219925.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2261..2701)
                     /locus_tag="NOB74_000720"
     CDS             complement(2261..2701)
                     /locus_tag="NOB74_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCI1219926.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2859..3623
                     /gene="map"
                     /locus_tag="NOB74_000721"
     CDS             2859..3623
                     /gene="map"
                     /locus_tag="NOB74_000721"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HCI1219927.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3655..4578
                     /locus_tag="NOB74_000722"
     CDS             3655..4578
                     /locus_tag="NOB74_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HCI1219928.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4803..5042)
                     /locus_tag="NOB74_000723"
     CDS             complement(4803..5042)
                     /locus_tag="NOB74_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1219929.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5047..5466)
                     /locus_tag="NOB74_000724"
     CDS             complement(5047..5466)
                     /locus_tag="NOB74_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI1219930.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5693..6931)
                     /locus_tag="NOB74_000725"
     CDS             complement(5693..6931)
                     /locus_tag="NOB74_000725"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1219931.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7038..7673)
                     /locus_tag="NOB74_000726"
     CDS             complement(7038..7673)
                     /locus_tag="NOB74_000726"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1219932.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(8015..8650)
                     /locus_tag="NOB74_000727"
     CDS             complement(8015..8650)
                     /locus_tag="NOB74_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1219933.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9162..10304
                     /locus_tag="NOB74_000728"
     CDS             9162..10304
                     /locus_tag="NOB74_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCI1219934.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10297..10503
                     /locus_tag="NOB74_000729"
     CDS             10297..10503
                     /locus_tag="NOB74_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HCI1219935.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10582..11775
                     /locus_tag="NOB74_000730"
     CDS             10582..11775
                     /locus_tag="NOB74_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1219936.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11980..13119
                     /locus_tag="NOB74_000731"
     CDS             11980..13119
                     /locus_tag="NOB74_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HCI1219937.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13112..13912
                     /locus_tag="NOB74_000732"
     CDS             13112..13912
                     /locus_tag="NOB74_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI1219938.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13912..14739
                     /locus_tag="NOB74_000733"
     CDS             13912..14739
                     /locus_tag="NOB74_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI1219939.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14717..15451
                     /locus_tag="NOB74_000734"
     CDS             14717..15451
                     /locus_tag="NOB74_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI1219940.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15551..16417
                     /gene="rfbA"
                     /locus_tag="NOB74_000735"
     CDS             15551..16417
                     /gene="rfbA"
                     /locus_tag="NOB74_000735"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCI1219941.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16431..17003
                     /gene="rfbC"
                     /locus_tag="NOB74_000736"
     CDS             16431..17003
                     /gene="rfbC"
                     /locus_tag="NOB74_000736"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HCI1219942.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17025..18053
                     /gene="rfbB"
                     /locus_tag="NOB74_000737"
     CDS             17025..18053
                     /gene="rfbB"
                     /locus_tag="NOB74_000737"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCI1219943.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18151..19002
                     /gene="rfbD"
                     /locus_tag="NOB74_000738"
     CDS             18151..19002
                     /gene="rfbD"
                     /locus_tag="NOB74_000738"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HCI1219944.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19036..21069
                     /locus_tag="NOB74_000739"
     CDS             19036..21069
                     /locus_tag="NOB74_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219945.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21113..22393
                     /locus_tag="NOB74_000740"
     CDS             21113..22393
                     /locus_tag="NOB74_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HCI1219946.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22603..23409
                     /locus_tag="NOB74_000741"
     CDS             22603..23409
                     /locus_tag="NOB74_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1219947.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23421..24641
                     /locus_tag="NOB74_000742"
     CDS             23421..24641
                     /locus_tag="NOB74_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1219948.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24631..26217
                     /locus_tag="NOB74_000743"
     CDS             24631..26217
                     /locus_tag="NOB74_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI1219949.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26256..28394
                     /locus_tag="NOB74_000744"
     CDS             26256..28394
                     /locus_tag="NOB74_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI1219950.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVCPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28762..29745)
                     /locus_tag="NOB74_000745"
     CDS             complement(28762..29745)
                     /locus_tag="NOB74_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HCI1219951.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30123..31514
                     /locus_tag="NOB74_000746"
     CDS             30123..31514
                     /locus_tag="NOB74_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI1219952.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31530..32570
                     /locus_tag="NOB74_000747"
     CDS             31530..32570
                     /locus_tag="NOB74_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI1219953.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32589..33674
                     /locus_tag="NOB74_000748"
     CDS             32589..33674
                     /locus_tag="NOB74_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HCI1219954.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33707..34669
                     /locus_tag="NOB74_000749"
     CDS             33707..34669
                     /locus_tag="NOB74_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCI1219955.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            34662..36089
                     /locus_tag="NOB74_000750"
     CDS             34662..36089
                     /locus_tag="NOB74_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HCI1219956.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            36091..37161
                     /locus_tag="NOB74_000751"
     CDS             36091..37161
                     /locus_tag="NOB74_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219957.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            37148..38569
                     /locus_tag="NOB74_000752"
     CDS             37148..38569
                     /locus_tag="NOB74_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HCI1219958.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            38582..39589
                     /locus_tag="NOB74_000753"
     CDS             38582..39589
                     /locus_tag="NOB74_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI1219959.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            39601..40605
                     /gene="neuB"
                     /locus_tag="NOB74_000754"
     CDS             39601..40605
                     /gene="neuB"
                     /locus_tag="NOB74_000754"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HCI1219960.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            40602..41750
                     /gene="neuC"
                     /locus_tag="NOB74_000755"
     CDS             40602..41750
                     /gene="neuC"
                     /locus_tag="NOB74_000755"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HCI1219961.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            41723..42400
                     /locus_tag="NOB74_000756"
     CDS             41723..42400
                     /locus_tag="NOB74_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCI1219962.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            42390..43532
                     /locus_tag="NOB74_000757"
     CDS             42390..43532
                     /locus_tag="NOB74_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HCI1219963.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            43545..44522
                     /locus_tag="NOB74_000758"
     CDS             43545..44522
                     /locus_tag="NOB74_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1219964.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            44522..45430
                     /locus_tag="NOB74_000759"
     CDS             44522..45430
                     /locus_tag="NOB74_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HCI1219965.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            45431..46183
                     /locus_tag="NOB74_000760"
     CDS             45431..46183
                     /locus_tag="NOB74_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HCI1219966.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            46188..47135
                     /locus_tag="NOB74_000761"
     CDS             46188..47135
                     /locus_tag="NOB74_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HCI1219967.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYNKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT        15784 a         7468 c         9072 g        14898 t
ORIGIN      
        1 ttttttgcat gtgtgcgaaa gtatactcaa gcccaatcgc catttcggaa aatcggtact
       61 gtagagccat cttcacggat tccgtcgata tccatcttgt cagatcctac catgaaatct
      121 acgtgggttt gacttctatt caatccagct tctgctaatt cttcatcgga catttctgta
      181 ccgcctttca cactgaaggc ataagcagaa cctagtgcta agtgattcga tgcgttttca
      241 tcaaataatg tattgaaaaa gatgatgcca gattgagaaa taggtgaagg gtcaggtaca
      301 agtgcgactt ctcctaaacg acgcgcacct tcatctgtat caagcagttt tgctaagaca
      361 tcttctcctt gttcggcaga aaaatcaaca acttttccat ctttaaaagt aaatttcata
      421 cccgagatga tggtgccagc ataactcagt ggctttgtac ttgaaatgta accatctact
      481 cgatgactgt caggtgctgt gaacacttct tccgtcggca tatttgccat gaatttttct
      541 ccacgagcat tatagcttcc agcgccttcc caaagatggt ttttaggcaa tccgataatg
      601 atatctgtac cgggagcagt atagtgaagg gcagaaaatt gttctcgatt caattcttct
      661 gctttttttg ctaatttttc atcatgcttc ttccatgcta agacagggtc ttcttcatag
      721 acacgagtcg ttttgaaaat ctgatcccat aatgcctcaa cttgtttttc ttctggcagt
      781 tctgggaaga cttttgctgc ccattgttta ccagccgcag ccacgacagt ccaactgact
      841 ttatttgctt gagttgcctt gcgtaaattc attagtgctt tgccattcgc tgattgataa
      901 gacgctactc gatggctatc tacaccagca aatgcatcgg gatcggcaga aacaacgctg
      961 atcctgcttg ctcctttttc aagccattca tccgcttgat cgattttaga ttgtggtaca
     1021 ttctcaatac gatccgttgc agcatgtaaa agaaattctc tttggatctg gtcgtcagtc
     1081 cattgaacga taacctcagc ggctcctagt ttataagctt cttgtgtgat caatcgagca
     1141 aggggtgcct gttccacgct gatctgtaaa acaactgtgt gtcctttttc tgtggctacg
     1201 ccagtttctg caattaagcg tgcatatttt tttagaagtt cattaaaatc agataacata
     1261 ataaaaattc ctcctcacca ttttttctgg taactattag catgatacca tttaattatg
     1321 attcaaacaa tgaggcttta aataaaaaaa ggaggttatt tttttaaggt taagtttcat
     1381 gatatatgtt actacttgct atttcagctt gtgaagaaaa tcaaaaacta attttgcata
     1441 tcaaaaaaaa catgttacaa tgaaattaat caatggtgga agcgttataa aaaaattaag
     1501 gagattaaaa aatatggcaa gaaaaaagac gattactaga gaacagattt tggcagctgc
     1561 ttatgaagta gctgccaccg atggatttac acgatttact gcgagaaaca tcgcgaacaa
     1621 aatgaattgt tccacgcaac cgatttatct tgagtttaaa aatatggatg acttgagaca
     1681 agctcttttt gagcagatct atgatcattt acaatatgaa gtgttcactg ttgagcatac
     1741 agggaatacg attatcgatc ttgcttttaa ttatatccat tttgcaagaa gagagaagaa
     1801 gttgtatcgt tcactgtact tagaagaata tggtggagga aaagagatgc agaatttctc
     1861 ttatacttac tttgtgaata cagtgaaacg cgatccagct tatgtgaatc tttcagaaga
     1921 gcagatcgaa tctttgtata atgggacatg gatcatagct actgggatcg cagctttgat
     1981 gtcttcaagc atcatccatc caactgatga acagattgaa aagatgatcc aagacagtat
     2041 agatgctatc ttgaaattca aagaaccaat cgaaatcgat tgaatatact caaaagttcc
     2101 acaaatcagt aggtaacaag agatgtgtca aaataaggaa aagttcgttt ttcttacagc
     2161 gtatgcattt ttaactcccg aagaactctt ccatgaatgc aatgaataaa agagccatac
     2221 agattgaata aatctggatg gctcttttat tgcaagtata ttaaattttt gcgactagtt
     2281 ctttagcgaa agcttctaaa ttttcgatat cttcttcttc agcattcaga tccactttaa
     2341 cattttcggc tccttttgat gcgcctgttt ttgcaaaagc agcatcgaaa tcatccaccg
     2401 atttgcagaa ttcatcgtaa aaagtatcac cagatccgca gacaccgtaa atttttccca
     2461 atagatccaa ttcttgcaag tcttcataaa agtctacgat ctcatcaggc agatcgccat
     2521 catcgtatgt ataagtagct actacgcaaa tatctgcctc ctcgaattca tctgcatcta
     2581 cttgggtaca ttcgttgatt tcgacttcga tatccagatt ttcaaatgct tctgcaacaa
     2641 tatcggcgat ttcttcagtg tttcctgtca tgctagcata tacgattttt gctaaagcca
     2701 tgatgtgcct cctcgtttat aattatttaa caattatgaa ttataccaaa acatcattga
     2761 aaagaaaata aaacctagag acacctgggg aatgtcattt ggctaaatgt atgccgctat
     2821 gttaaaatga gagggatttg taaaaaggag acgaaaatat gattacttta aaatcagcac
     2881 gtgaaattga aatgatggca gaatctggag ctttattagc agatgtacat aaaaatctgc
     2941 gtgattttat aaaaccagga atcacaagtt gggatattga ggtatttgtc agaaactata
     3001 tcgagagtca tggcggaatt gctgcgcaaa ttggctttga agggtatgaa tatgcgactt
     3061 gtatcagtat aaatgatgaa atttgtcatg gattccctcg taaaaagcct ttgaaaaacg
     3121 gtgatttggt aaaagtcgat atgtgtatcg atttgaaagg cggcatttct gattcttgtt
     3181 gggcctatgt agttggagaa tctacacctg agatcgaccg attgatggaa gtaacgaaga
     3241 aagctttgta catcggtatt gagcaagcac aagtagggaa tcggattggt gacatcggtc
     3301 atgctatcca aacttatgta gaaggcgaaa atctagcgat cgttcgtgat tttattggtc
     3361 atggcgttgg tcctacgatt catgaagaac cagcagttcc tcattacgga gaagctggaa
     3421 aagggttgcg gttgaaagaa ggcatggtta tcacgatcga acctatggtt aataccggaa
     3481 cttggaaaat gaaaatggat cctaacggct ggactgcgta tacaagagac ggcggacttt
     3541 cttgccaata tgaacataca ttggctatta ctaaagatgg tccaagaatt ttgacatcac
     3601 aaggagaaga aggcacttat tgatctatcc agtcaatagg tacgggagag gtacatgaaa
     3661 gtttggaaca aaataaaaca aaatgaaaat ctgatgcgct ttattgagac gactcaaaag
     3721 cgcatcactg attcagaaat gagtacgacc tctgtcgtcg ttgcttatta tttactcttg
     3781 tctttatttc cattgattat tgcttttggt aatattttac cgtttctcca catcgatcaa
     3841 gagactgtac tgacctattt acgagaagtg attcctgaga ccgtttacca gtttatcggt
     3901 cctgcaatca aagacctttt gacacaaagt tcaggaggct tgttatccgt ttctgcatta
     3961 gcggctttat ggtctgcaag tcaaagtatc aatgctttgc aaattgcgat gaataaagcg
     4021 tatggcgtag aaaatagaaa aaattttttg atcgtccgtt tcttctcact aattgtcatt
     4081 gtcttgttca tgattgctat tagtggggta actatcgttc ttgggttggg acagctgatt
     4141 ttggatgcta ttcagccaat cgtacaaata cccgtgaact ttatcgatca gttccaaact
     4201 ttgaagtggc caatcacatt ggtagcttta tttgtcatca tgttcttgat ttatttaatt
     4261 gtccctaatg ctcagttgaa gttgaagacg atcattccgg gcacgatctt cgctactgtc
     4321 ggctggatgc tgttatcaca agtgtttagt atctatgcta ggtattttgc aacgaggatc
     4381 agcggttatc agatcatagg aagttttatt gtactcatgc tttggcttaa ttttgctgct
     4441 acgatcatca ttttgggcgg aatcatcaat gcagttgttc aagaatacgt gacgggtcat
     4501 caaatcaaaa aacgtcgaga tccaagccga aaatggttca ataaattgaa aactaaattt
     4561 tctcataaaa aaaagtagaa acaagagttc ttattgtaaa tttatatcag taatttattt
     4621 gaaattttat atctaatttt caattatccg cataaacact atacattcaa gcattttgaa
     4681 gtatagaaaa acactcatct taccacgaat ttaccacgat tgaatgagcc ttgatatgac
     4741 cgtaaaacta ctaagggaga tagcacgaaa ctgtgtatct cccgattttt ttatacagtt
     4801 gattacttca ctccgatttc aaatttcaat attgctttca tcatgtctgt atgaatttct
     4861 ccttttagtt cttcatcaac ctgcataatg attttaccac tttcagagtg gtaaaaagga
     4921 cgcaagcata atttagaaat ataaccgtca taaaacttca aaatctcttt aactgccatt
     4981 tcatctccgc ttgacgcttt gcaaatcaat tcaaaagagg gatagccata atctttactc
     5041 atttctttac ttcctttcgc tcaaaagcat ttttaacttc cttagtcctc tagttcttct
     5101 actgcaaata gcagaacgtg atacatggta cagttctgaa atttctctgt cgttcattcc
     5161 ttgaaaataa cgtaataaaa tcgcactacg ctgtttttct gacagtctat gtaaaactgt
     5221 accaagtgtt tcatcagata cataaattgt aaagtgcaag actttaaatg atacacaatc
     5281 ataaaaacag gtatcaatcg ttccacgttc aacttgtttc gtttcggcta tttcacaaaa
     5341 caatacttca cgtttagaat gtcttgcaag ctgtctgttt cgacttttca ctttgttctt
     5401 aatgacaatc agcattaaag aattgaactg taatctgacg atatgctcga aagaagatgt
     5461 cctcataatc tcaccccctt tctgctaatg ctgaaatata taaacggaat accgtttata
     5521 ccctttagaa atacagaaaa atggtaagaa aaaagcccac acaaaacata tatttgtgcg
     5581 agccttaaat actgcaatat tactctttct tttataacac tatcctttta gcagatttca
     5641 aattttcttt tatatattgt ttttagccta acatactatt taaccccttg tattatatct
     5701 ctaacttttg aaaaattctt tttgaatata ttgaaatcat gattgaagca atagaagcta
     5761 caaacataac aacccatgtt tcttgtataa atacatcgaa taaaataccg taaaccattt
     5821 gtccaatagg ttgaccgcac atagcaactg ctaccagcgt agccattatc tttcctacta
     5881 attgcggtgg tgtttgtgtc tgaacaagag tgtaaatttg aacaacaaac atagtagata
     5941 cacccatagc cacaaagcac atcactgtaa ctacccagta ggaaactatt gcaggcaatt
     6001 ctaaaaatag cgaaattccc ataagtaaaa cagaaacaga acaaataagt aacaaggtat
     6061 aaaggttttt tagttttaac tttgaagcaa caagagctgt taaaatacca ccacataaac
     6121 cacctaatga taatgctgat tgtgaaaaac catatagtgt atctggcatt tttaaaactt
     6181 cagaaattaa gataggcaga ccaacaatta aaacagcact taaaaccaaa ttgaaaatgc
     6241 aaaccaaaaa gattacggat ataaaaatgg gtttctcctt tttcaaaaag gtataactat
     6301 cttttaaatc gtttttagca actgcaatta cacctacttc acgaggtctt ttttggtgtg
     6361 gaatatggat aaaaatttcc ataatggctg aaaaagtaaa acatataata ctaacaatta
     6421 aaatgggatt gataccataa aattgaaaaa ctactccgct tatagctggt ccgataaagt
     6481 ttgctaaagt atttacttga tttattatag cattaccgac ggtaagttta tctgatgata
     6541 ccaatagagg aatacttgct tgtaccgctg gttgatatgc accagaaata ccataaagta
     6601 acatcaaagc aacaataaac aaaggtatga taggaatttt tcccaatgac aaataaaata
     6661 ctaaaattat gattgctgtt acaaaatcta gtatgaccat aatgtttctt ttatttgtcc
     6721 tgtcagcaat aataccacct accagcgaca aaataaccat aggtaaaaaa gagcaggctg
     6781 tagcaatacc aaacaaagct gatgaaccag tttcttttaa caaatagtac ggtaatgcaa
     6841 atcgtaggat agcgtttcca aataaagaaa ttatctgtcc tataacaaca agtataaaat
     6901 cacgattaaa aagttttttt tctgcttgca taaaatctct cctttttatt taatcaaaca
     6961 gaccgtcggt ttatataatg gtttaaataa actgctcttt tatagagcag tctatcgtat
     7021 agggataaca aatacagtta tttacaaaac tgtataaatg cagaaattgt ttcttcgtct
     7081 aataatgtgt ctatgcctat tccatttaaa agggcattga atgtattgca acgtttttcc
     7141 ataccctctt tatccgtcat ttcaactaat gggttgagcc atacattact taataccatg
     7201 ataacttctg caatttcatg tgaattttca atctccaaag acttatcctt gataccttgt
     7261 tctaaaacgg gttcaacaaa ttcaggtact acaatttcat acatttgttc tatttgcata
     7321 gcaagaaaac gaggattgtt taatagttga ggagaaactg tcaataaaac gctttggtta
     7381 gaattgaata ccgctgtctt aaatatttct cttaactttt ctaaaccgtt taaactatcg
     7441 ttatctctaa ttttagcaaa tattactgca ttttcatttc caattctttg aaaaattgct
     7501 tttaaaatat cttcctttga atcgaaatga tgataaatag cacctttaga aagttttgtt
     7561 tcattgataa tatcttgcaa tgatgtgtta tcatatcctt tttcacaaaa catttttgta
     7621 gaaacatcta aaatgagttt tactgtttct tctggatatt tatttcgtgc cataacttac
     7681 ctccaataca aaccgttggt ctgattaaag tatatcttag tattttatgc ttgtcaatat
     7741 aaagacttgc aattttataa aaatgcagaa tgcaagcctt tttcatttat tctacaatct
     7801 tccagttgct ttccttatgc ggtgtcaatt catactgtga tacctgcgtt gcctttgcct
     7861 gatttaccac aaatcagatt ttatcccttt cttcctcttg attgcccaca acagaaaaga
     7921 aaaagccctg tcaagagctt tgccaccatt ggtggtgctt tgcactcttg atcgggcttt
     7981 ttgtttgctg tatcttctcg caagaggaaa aaagttactc gtcctcatca tcaaaattgt
     8041 tattccttaa tacttctcgt aacagttcca tatcttcttt tgagttcggg tttatcattt
     8101 tcacgacttg ataaggtgtc ttatacttat gtccctctat gctttcccca aacatatcca
     8161 tactgtataa atcatcatag cggtctaata atttttgaaa cttcaaatgc tggataaatt
     8221 ctttgattgg gtaaaggtcg gacgcttcaa tgcttttccc gttgatatag tctgtaatat
     8281 attcccgtaa cttttctaac tcatattcca gccattcttc ctcgctgtca aagaagttat
     8341 catagtgtcc atgtttcagt tctgcattta gacgttcttc ggctcttaaa aactgacaga
     8401 cttccttttc agattgattg acatacttcc attctcccga caacaattca ttgggcgtaa
     8461 cgtccagcac ttccattatc ttttccagcg tttcataggc aggatagttc aaccctcttt
     8521 caatcttgga aaggctctgc atattgatac cgattttgtc cgcaagttcc tgttgtttca
     8581 ttcccctaaa ttttcttatg gtctgtatat tatttcctaa atggcttatt ttcattgcat
     8641 aaccctccat atctcgttat atcttcgcta ttataagtct atcatgctta atatgatttg
     8701 taaaggcaaa aaaagatatt gacaaataag catataagaa ttactatgtt cttgtaatcg
     8761 aataagcaca atagaatgaa atataaaaac attcaaaaag aaatacctat ctgattaaat
     8821 ccgtagatat gaatatcggt tgaaatggaa cttgttagaa aaggcaaaac agaacttgct
     8881 gacaaagtat ttctgacacg gtggcggaag cctctcaggc ttaccgccat gacaccttgt
     8941 gtcaagggga agaaatgctt tgtcggctgg cgagcctgcg agccttgtct gtgcccccgt
     9001 tatctaacag gggggcacta tttcacaaaa gacaagtcaa aaaccataca cccccaaacc
     9061 tgtgagtagt aatgagaggt tttaagaaga tagtacatat cacacttttt gaaaggtggt
     9121 ttacaggtat ttcaaggcta ttgtgggatt ggaggaatac aatgaacaat ttagaatttg
     9181 cacttgaaat gaagaacaaa cgtcttgcca gcggtctttc acaaggagaa cttgcaagtc
     9241 ttacccatgt atcaagatat agtatcaacc gctttgagaa cggaaaagct aacgccagca
     9301 aggaaacaca gaacattatc ctgcgttgtc tgaattacta tatctgcgat aagccttttt
     9361 atctgctcgt tgattatctg tctgtccgtt ttccaacgac tgacgcattg gaagttatcc
     9421 gaaaggtgct tggcatgaaa gcagattatt ttatccatta tgactatggg tattatggct
     9481 ataaggagca ttatgcttac ggggaaatca aggtcatggc ttctgatgat gaacacatgg
     9541 gcgtattttt agaattaaaa ggggcaggct cacgcaacat ggaatatgtc ttacaggcac
     9601 agaacaggga ctggtattca ttcttaaacc gctgtcttga ctgtggcggt gttatccgac
     9661 gttttgactt ggcaatcaat gatatgtgcg gtctgctgga tattcctgtg ctatctgaaa
     9721 aatacagaaa tggtggtgcg gaatgtcgct gtaaaaacta tgaaaatgta caaggtggaa
     9781 aattaagcgg aaaaaaccgt aatttagcaa gtacccttta tatcggctca aaggcaagca
     9841 caaaatattt ctgcctgtat gaaaaacaaa aggaacaggc aacgaaaaag aaacataccg
     9901 atattatcaa ccgttttgaa attcgtctgc gtgacaaaaa ggcggtacag gcagttgaag
     9961 aactgttatt gacgtataac cctcatgggc tggtgtttta tctcattacc gattttgtgg
    10021 aatttcctga ctatccattg tgggagatat tcatttccca tgacagttta ccttttgaaa
    10081 tgaaccctgt acctgtcaat atggaacgca ctctgcaatg gctggaaaga caggtcatgc
    10141 cgtcaatcgt gatgatagag gaaatcgaca ggctgacagg ttcaaactac atgaaaatga
    10201 ttgatgaatg tacccacctt tctgaaaaac aggaaatgct tgtggaacag atgtgtacgg
    10261 acatatcaga cgtaatcgaa agtgaggggg tgttttatga gtaatacaca ggatattccc
    10321 gtatgggaaa aatacaccct taccattgaa gaagcgtcaa agtatttccg cattggagaa
    10381 aacaagttaa gacgattggc agaggaaaac aaggacgctg gctggctcat tatgaatggc
    10441 aaccgcatac agattaaacg ccgacagttt gaaaaggtta ttgataaatt ggacgcaatc
    10501 taatgcaaat gagccttgta tgtgttatga tgaacacaag tcatatcaag gctctttcca
    10561 acaaggaaag gagcagacac catgaaagaa aaaagacggg ataacaaagg tcgtatcctg
    10621 catactggag agagccaacg aacagacgga aaatacttat ataaatatgt agacgcattg
    10681 ggaaacacaa aatatgtgta tgcttggaga ttgacaccca cagacccgac accaaaggga
    10741 aaacgggaaa aaccctcact tcgagaactg gaacagcaga taagacggga tattgaggac
    10801 ggtatcgaca gcacaggcaa gaaaatgacg ctttgccaac tctatgccaa acagaacgca
    10861 cagaggacaa atgtgaagaa aagcacacag aaacaacggg aacaactcat gcggttatta
    10921 aaagaggaca agttaggtgc taggagcatt gatacgataa aaccctctga cgctaaagaa
    10981 tgggcgttac gcatgaaaga caaaggcttt tcctacaata ccattaacaa ccataaacgc
    11041 tcgttaaaag cgtcattcta catagccata caagatgatt atgtgaggaa aaaccctttt
    11101 gatttcaagc taagtgaagt catagaaaat gataccaaag agaaagtcgc attgacagag
    11161 gaacaggagc aagccttatt gtcatttatt aagacggaca acgtgtatca caagcattat
    11221 gatgatgtgc tgatactgtt aaagacagga cttcgtatct cggaactgtg cggactgaca
    11281 gtagccgaca ttgatttcaa gaatgaagtt gtgattatcg accaccagtt actaaagagt
    11341 aaggaacagg gctattatat tgaaacgcct aagacgaaaa gcgggataag gcaagtgcca
    11401 ttaagcaaag aaacgataca ggcatttcaa cgggttatca acagccgacc aaagataaag
    11461 tcgatagagg tagacggaca cagcggtttt gtgtttatca atccgaaagg taatccaaaa
    11521 gttgccattg attataacgc cttatttatc cgtatggtaa agaaatacaa caagcaccac
    11581 aaggacaatc ccttgccaca tattacaccg catacgctac gccatacatt ctgcacaagg
    11641 ctggcaagca agaacatgaa cccgaaagat ttacagtata tcatggggca ttcaaacatc
    11701 agtatcacaa tgaactggta cgctcatgcg tccatagata ccgcaaaatc agaggttcag
    11761 cgtctaatcg catagaagta tttaccacga ttttaaccac gattgacagg gaaaatataa
    11821 gaagatagac ctagatatgc gaggtttacc acaaaagcaa aatgcccgta gagccgataa
    11881 aataaggctt tgcggacatt tgagaagata taaaaagata gtcaaaaaga catatataat
    11941 ttataataat tatgactctt aattaaagta ggtgcccata tgcttgtttc ttttagtatg
    12001 gttataagat tttttctgac aattttatta tcactgatat taacacctgt attcaaaatc
    12061 atttcagtac aaacaggtat ggtcgacaaa ccaaatgaaa gaagaataaa taaagttcca
    12121 atgccttcag cgggcggact gcctatcttt atttcatttg ttatatcgac tttattctta
    12181 ttccgtaaaa ttatccctca atcgtatatt gtaccgatct tgattgcttc tttagtaatc
    12241 atagtcacag gagtgctcga tgataaatat gagctgacac ctaaacaaaa aagtataggg
    12301 atcttgattg cttctcttat tatttatttt gtagcagata tacgtattga ttccttcacg
    12361 cttcctttta ttggatatat ccaactaggc tggcttagtt ttcccgtaac gattttttgg
    12421 atcttcggta tcacgaatgc ggtcaatctg attgacggtt tggatgggct ggcggcaggg
    12481 atttcattga tcggtttaat tacgatagga atcattggat attttttcct ccatgcttct
    12541 acagtgtata ttccagttgt tattttctgt cttgtagcaa gtattatcgg tttttttcct
    12601 tacaattttt atccggcaaa gatttattta ggcgatacag gagctctatt cctagggttt
    12661 atgatggccg tcctttcact acaagggctg aagaacgtga cttttgtttc atcgatttct
    12721 ttgctgatcg tcatgggagt gccggtaaca gacacgtttt ttgctatcat taggagaaaa
    12781 gcaaaccgtg tttctttttc tacagcagat aaaaaacatc ttcatcaccg actaatcagt
    12841 ttaggcttta ctcataaagg tgctgtcctg acgatttatg cgatggcttt gatgttttct
    12901 ttcacagcta tggtcatgaa ttatactgga agaatcggaa cgatcatatt gattattgcc
    12961 atgttgtttg ctgcaatttt attatttgaa ttgattggtc tgatcaatga gaaacatcag
    13021 tttattttaa aaacattgcg atttttaggg aataaagagt accgtacgca agtaaaacag
    13081 aaatatttga agaaatggaa ccgtcatata gatgaataac aaattaaacc agccgatcct
    13141 tattagtatt gtgacggcaa acagtgataa aatttttcgg acactagata attttatttc
    13201 aactgtaaaa gatgaaacag cagtaaaaat ccgaattttt gacaacaatt cacttcccga
    13261 gtacaaaaaa agactaacag agtataggaa atatccctac atcgatatct attttcatga
    13321 tgaaaattcc ggatttggtt atggacataa tcacaatctg atagctagcg attctcgcta
    13381 tggcattatt tgtaacccag atattttagt ggatgaagag acagttacag cattggtctt
    13441 gttattgaaa gaacatccgg aatgtgcgat gttagcacct aagattctta atgaagatgg
    13501 aacaactcag cacctcatcc gtgagcagct ggctgttttt gattacgttt tgcgctttgt
    13561 gcctttcaaa tgggtcaaaa aaaagtttga caaacgactg gctgtgtttg aatgccgagg
    13621 attgcctact gatgctaata gttatgtacg gatgatctca ggtagtttta tggtagctga
    13681 tattgataaa tttaaagaga taaaggggtt tgatgagcgt ttcttcatgt actttgaaga
    13741 caacgacttg tgtttgagtt ttgaaaaagc aggttacaag ttattgtaca caccctttta
    13801 tgcagttatc catttttacg ggaagggtgc gcatcgaaat gcaaaactgt ttcgcgtgtt
    13861 tttgacttct atgatgaaat ttttcaataa gtgggggtgg cgttttttct gatgaaacca
    13921 gaaatattag tagtcgttgt gctttatcag caactattca gtcaatctcc agcttatgga
    13981 ccattaagca aagcacttag cgaaaagcaa attcagctta ttatttacga taatagtcct
    14041 caaaggcagc aaaatgagct gtttgaaaaa gaaaatatcg tttatcatca tgatccgcaa
    14101 aatcctggtt tagcggtggc ttataatttt gcgttgtctc aagcagatga aggaacacgt
    14161 tgtctcgtca ctctggatca ggatacgagg ctagtcgacg attattttga actattgcgt
    14221 aaagtaacct ttacagatga atgtgttgct gcagttccga tgattttttc tgggagccga
    14281 caagtttctc ccctatattc agatcgttat atcaatcgta cagctcaagc agtagaagtt
    14341 gaaggcccaa cagctgaacg aatcatggca atcaattcag gtgttgcctg gtctgtcaaa
    14401 tttctaaaaa agattggcgg gtttaatcct gctttttctt tagatttttt ggatcattgg
    14461 ctgttttgga aagtggatca gttggaaaaa actgtggaga tccttcctgt acgaatggaa
    14521 catgatcttt cggttttaga ctatgaaaaa gtttcaagta atcgataccg ttctatttta
    14581 caagcagaaa atcgatttta tcatgaatat gatcaaaggc atttatccag tcaccgacga
    14641 caattattgt taagaacagc taaacagttc ttgaccgtca aaaaccggca tatctggcgg
    14701 atgactttgc gctcatatgt taagaattgg aaggtgtgaa ttcgtgcgtt cggtttgtat
    14761 agctaccttt aatggaggca gatatttaag agagcagtta gatagtattt tatctcagct
    14821 ttcagcagaa gatgaagtag tcatttctga tgatgggtca gtagatgata catgggatat
    14881 attaactgaa tacgcagaaa aagataagcg aatccagctt ttttcggggc ctcgtcaagg
    14941 attgatcgct aattttggtt atgcgatcca gcagacgaaa ggagatctaa tctttttggc
    15001 agaccaagat gatgtttggt tggagacaaa agtgaaaaag atcactgact attttgagca
    15061 gaatccggat cagctagtag tagtttctga tttaatcatt gtggacagcg agctgcaaga
    15121 gatccatgat tcgtattttt cgtttcgaaa ttccaaagaa ggatggctta ataatgtgat
    15181 aagaagtcac tatattggtg ctggtatggc tttccggtct tctttaaaac ccgatatttt
    15241 gccgatcccg tcagaagtgc cgatgcatga tatgtggatt ggtttgctgg gaggaaagaa
    15301 gactgggttc ctaagagaac cgttaactct gtaccgaaga catgatttaa acgcgagtga
    15361 gattgaaaca cattctaaat tacggcaaaa aatttcttgg cgtgttcatc tgattacggc
    15421 gttgatcaaa cgaaaatggt ttaaacgttg ataaaagatg tttaaatcct taatatttcc
    15481 atgacaaata taacaattga tgagataata acaaagtgaa atttgaaatc aaaaaggaga
    15541 gcagatatcc atgaagggaa tcattcttgc tgggggcagc ggaacacgtc tgtacccttt
    15601 aacaaaggca acatcgaaac aattgatgcc gatttatgac aaaccaatga tttattatcc
    15661 aatgtctact ctgatgttgg cgggaatcaa agaaattctg attatttcaa cgccacaaga
    15721 tacaccacgt ttcaaggaat tatttggaaa cggaaatgat ttaggactgc agatcgaata
    15781 tgcagtacaa gaaagtccag atggattggc acaagcgttt atcattggag aagaatttat
    15841 tggagatgat agtgtctgct tggtattagg ggacaatatt tactatggtg gcggtctgtc
    15901 taaaatgttg caacgagcag cttcaaaaga tacaggcgcg acagtatttg gctatcatgt
    15961 caatgatcca gaacgctttg gtgtagtaga atttgatgag aatatgcaag ctttgtcgat
    16021 tgaagaaaag cctgctcagc caaaatcaaa ttacgctgta actggccttt atttttatga
    16081 caatgaggta atttctatcg ctaaaggtat caaaccttca gaacgtggag aactagagat
    16141 tacggatgtc aataaagcat atttggataa aggaaaacta tccgtagaac ttatgggacg
    16201 cggatttgct tggcttgata caggaacaca tgaatcattg cttgaagcat ctacctttat
    16261 cgaaacaatt gaaaaacgtc agaacttaaa agtggcttgt ttggaagaaa ttgcttaccg
    16321 tatgggctac atcgataagg aacaattgct ggcccttgca cagccattga aaaaaaatca
    16381 atacggtcaa tatttattga atttggccgc tgaataagga gtccttacag atgaaagtaa
    16441 cagatacaaa attaacagat gtcaaaatcg tagaaatgga cgtctttggc gatcatcgcg
    16501 gtttcttcac agaaagttat tcaaaagcaa aatttgcaga acatggattg aaatatgact
    16561 ttgttcaaga caaccattca ctatcagctg aagctggtgt ccttcggggg cttcatttcc
    16621 aaaaaggaga agctgcacag acaaaattga ttcgggtagt cactggagca gttttagatg
    16681 tagtagtgga tatccgcaaa ggtagcccga cttatggtca atgggacgga tttatcttat
    16741 ctgaacataa tcatcgacag ttgcttgtac ctaaaggata tgcccatgga ttcgttactt
    16801 tgacaccaaa tgtgaacttc ctttataagt gtgataatta ctataatgca gaagcagatg
    16861 ggggcatcgc atttgatgat ccagatttag cgattgattg gccaattgat ccatcaagag
    16921 cgattatgtc ggaaaaagat caccgtcatc cgacattaaa agaatttgaa gcagaaaatc
    16981 catttgttta cggagaaatc taagaattaa ggagaaattt tcttatgaaa aacatcattg
    17041 ttaccggagg tgccggattc atcggctcta atttcgttca ttacgtggta aacaatcatc
    17101 cagaagtgca tgtcactgtt ttggataaac tgacttatgc aggaaacaaa gagaacttgg
    17161 ctggacttcc tagcgatcgc gtagaattgg tcgtaggaga tgttgcagat gcagaattag
    17221 tggaccgtct agtaaaagaa gcggacgcag ttgttcatta cgcggcagaa tcccataacg
    17281 ataattcatt aaaagatcct ttcccatttg tacaaacgaa tatcattggt acgtatacac
    17341 ttttagaagc ttgccgcaag tatgatgtac gctatcatca cgtatctact gacgaggttt
    17401 acggcgatct tccattacgt gaagacctgc caggacatgg ggaaggcgaa ggagaaaaat
    17461 tcactgcgga aacaccatat aatccttcaa gtccatattc ttctacaaaa gctggttcag
    17521 atctgttagt aaaagcatgg gtgcgttctt ttggcttacg tgcaaccatt tcaaactgtt
    17581 caaacaacta tggtccttat cagcatattg aaaaatttat tcctcgccaa gtaacgaata
    17641 tcttaagcgg tattcgtcca aaattatatg gcgaaggaaa gaatgttcgt gactggatcc
    17701 atacgaatga tcattcttca gcagtgtggc tgattttgac gaaaggcaga attggcgaaa
    17761 cctatctgat cggtgcagac ggtgaagaag ataataagac cgtgatggaa ttgatcttag
    17821 aaatgatggg tcaaccaaaa gatgcgtacg accatgtaaa cgaccgtgca ggacacgact
    17881 tgcgttatgc aatcgattcg acaaaattac gggaagagtt aggatggaag cctgagttta
    17941 cgaacttccg tgatgggttg gctgacacga tcaaatggta cgaagaacat gaagactggt
    18001 ggaaaaaaga aaaagaggcc gttgaagcag catatgccaa aaatggacaa taatacagag
    18061 aaaatgtcac tgtattaatg gaaaaacaca tgtgaggcag gcgctcgcct gtctcttttt
    18121 taaaataaaa atcaaggagc ggataatcat atgtttttat taactggagg aaatgggcaa
    18181 ctaggtacag aattgcgcca tttattagat gaaaaaaatc tgcaatatgt ttcaacagat
    18241 gcaaaagact tggatatcac agatgccgag aaaacaatgg cttacatcac agaattaaaa
    18301 cctgatgtta ttttccattg tgcagcttac acagcagtag ataaagcaga agaagaagca
    18361 aaagaattag atgagaagat caatgttgat ggtacaagaa atgtagcact tgcagcaaaa
    18421 gctgtgaatg ctcaattcgt ctatatcagt acagactatg ttttcgatgg aaaaaacaaa
    18481 aatgtagaat acgaagtaga cgaccaaacg aatccactaa atgaatatgg tcgtacgaaa
    18541 ttattaggcg aaaaagcagt agaagagatt ttagaagact attatatcat acgaacttct
    18601 tgggttttcg ggatctatgg acacaatttc gtcttcacga tgcaacgcct agcggaaacc
    18661 cgcgacaaac tgactgtagt aaatgaccag tttgggcgac caacttggac acgtactttg
    18721 gcagaattta tggtatatgt catcgaagaa aaagcaccat ttggtattta tcatttgtcg
    18781 aacgaaaata gctgttcttg gtatgaattc gcaaaagaaa tattgaaaga tacagatgta
    18841 gaagttgcac ctgttacgtc agaagaattt ccgcaaaaag caacacgtcc gcagtattca
    18901 gtcatgagcc tgaaaaagac agaagagtta ggatttgtca taccaacttg gcaagaagca
    18961 cttgcgcaaa tgctggaagc tgccaaaaaa atgaataagt aatttccttt tatcaaatag
    19021 aatttggagc atgatatgga aaaacaaaca agaagtgcac gacgaaaaga aaagccaaaa
    19081 gcgaaccagg cagattcgaa tttggtgctt gacctgtttc taaaactccg ctatcttatt
    19141 ggcgttttag tcatcgtggt catcgttact tttaatttaa acggaagttc acttggtgtt
    19201 tgggataaat atgtgtcgca aagagacgat gggaaaaaaa ctgatgtgat ttttggacag
    19261 aatcgggaag tgcggtcaga cgaatggctg gtgcagacac ctttttacct ctcacaagct
    19321 gaagaggact ttccgttggt gaacgaggat tattcattaa acggacaaaa catgatcatt
    19381 gcgtataatt ctcctgtaaa ggatattacg gttatcggaa aaccattcaa ctggggattc
    19441 tttttcctcg gaagagatcg aggactttcc ttttattggg cgatgaaatt agtcgtcatg
    19501 gtcttgcttg gattcgaagt actgatgata ttaacgaaga gaaaaaaagc tctatcgcta
    19561 atcggtgcat ttgcgctgac attttctcca gcagtccagt ggtggttcat gcaacatgtg
    19621 ggcgatttga ttttctttac tttgggactg atgactgctt tttatcatta tttctacaat
    19681 catgataaaa aatggctacg aacgttgatg atgcttttgg tggttatttt cggtattggg
    19741 tttattttag tgatttaccc agcccatcaa gtgatgctgg cgtacttgct gattttttat
    19801 tttgttggcc tgcttattta ctatagcaag aaagtttcat gggatctgtt ggatgtagtg
    19861 ttgattggag gggcagtttt atttattggc ggagtcatgg ttcatttctg gctaacgtca
    19921 aaagacgcat tgttagcttc tttgaatacc ttatatccag gaaaacgggt aagtactgga
    19981 ggaaagtgga cgattggcga atttttttct ttccttacaa attggaaaat tccttttgaa
    20041 gatatcaact attcgaataa ctctgaagtg gccctgttct atcacttttt tccaactgta
    20101 ttcctagcaa gtccatttgt gttatttggc aaaaaagata gcgaacaaaa gttactggga
    20161 cgtattttga tgattttttg tctgttttct atcttttgga ttaccgttgg gttgccaaaa
    20221 tggctagcag aaatcactct gctgtcttat gttcctccat taagagccat ccttactttt
    20281 agttttgcgg cttgtttatt atcgatctgg tttatcgctt atatttggag agaagatgtt
    20341 attcctattt ggtataaatt cattttgttg gcagtaaatg catggtctta tttctatgcg
    20401 attacgcatt cgaaaatgga taattatttt tcggattttg aaaccatcgc agttgctgtg
    20461 ttgggaacag tgattttagc ttttgcatta tttggctgga gacgcttgtt ttacctcgct
    20521 tttgccgcct tagttatcgt atctggcttt ttcgtcaatc cagtcgtaga aggtacagga
    20581 gcgatttttg aaaaaacact ggcaaaagaa atccaaaaaa tcgatcaaca agatcctggt
    20641 aaagtttggt tgtctgaaga tgaattatat aacttcaccc caacattggg agtgaaatcc
    20701 ttcaatacag tacgctttta tccagatata gctgcatgga agaaaatcga tccgaaagaa
    20761 gaatacgaga agtattataa tcggtatgct catacaagag cttttatcgc taaggaagat
    20821 acaaagttca ttttagatcg tccagatatg ttttcggtca cgttgaattt tgaagacgca
    20881 gaaaaattag ggatcgacta tgtgatcagt aaacgaccat taactgatta caaccaatta
    20941 tatgaagcgc agttcacgca gctatatgga ccggataaag acggttatat gatttttaaa
    21001 gtagaatatc cggattatcc agatgtacca caaacacaaa ctcaggaaaa tcagctagtc
    21061 gtacagtaat aggctagctg agaataatcc tgaaatgtta gtagaaagga gagtggagat
    21121 aattcaagca atcgtacaaa aatttgtcaa caaaatgagt gtcggtttct tgcttttgtt
    21181 actgacgcta gtcttttttg tttggacagc agggttaggt tttccagcaa ctttgtttat
    21241 atataacaat agttcattac ttatcgcttt tagtgtggct attttgctca ttttaaatgt
    21301 ttataaagca aaaggcgtcg attttcttta tctaggtgtt gcgcttgccc ttttcatttt
    21361 cttttcttac tttcgggaat taagaaatga gtctttattt ggagacttac tgtttccttt
    21421 gattatttta ttttgtttag taattaaatg gatcgagtgg acaaaatggg atcgcggtat
    21481 ttatctgatt gtcttttcgg tcttcctcgg aatcacgtta tatcgtgtat ttacagagat
    21541 ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg atatttggat
    21601 caatacgaat ataatcggaa gttctttgat gactcttgct ttattgatca gtggatttgc
    21661 cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg ttgcagcttt
    21721 tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg tttttgcgat
    21781 attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta ttgcttacac
    21841 ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg aaaaagtcaa
    21901 tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag gagaaaaatc
    21961 tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc aatttttagg
    22021 aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat ttgggattgc
    22081 tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt tatccaacgg
    22141 gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta tggaggatac
    22201 attgacttca tacccatggg ttccgattat ttatatcctg ttggctatgg ccgttcatcg
    22261 atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat atgacgatat
    22321 gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt ccaggatcca
    22381 acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg cagccttttt
    22441 tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga aaatcttgta
    22501 tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat ggtaaaatgg
    22561 cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa agatttgtat
    22621 ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc gatcaatgac
    22681 ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat caatccgcta
    22741 tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca aatgatcgat
    22801 gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt cttcttctca
    22861 gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt aaagaaagtc
    22921 gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta cacccactta
    22981 ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc ttcagcaatg
    23041 tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg attgacttgg
    23101 ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac gatcgtgctg
    23161 cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga ttcaggtctt
    23221 gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg tgagtcattt
    23281 ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg ggttttcacg
    23341 ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca tttttcagat
    23401 gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat atcacaaaat
    23461 cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat ccttttaaga
    23521 aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata aaaaaaggtg
    23581 agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg aaaatcatta
    23641 cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc tcagctttgc
    23701 tagaactagg atcaggattc aatcctgagt attctggcta tgaaaatatc tatttaaatg
    23761 gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat atcattgaat
    23821 ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc gggatgttcg
    23881 ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt gtggatgaag
    23941 cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt acagaaatca
    24001 agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt cgtcgttttt
    24061 gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat acgatggaag
    24121 taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg gatcggaata
    24181 aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa gcggaattgt
    24241 tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta tacgttaaag
    24301 taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt gcgctacgaa
    24361 cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc aagattcctt
    24421 ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg ttagctggtg
    24481 aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg gtatataaga
    24541 caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc gtggtcttag
    24601 accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat ggacctagat
    24661 gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa agttttagag
    24721 tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca atgtgaagtg
    24781 agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc tcaagatgga
    24841 ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca gacatttgat
    24901 tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac attgaagaaa
    24961 gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa cttggcgcat
    25021 aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta tggtctccta
    25081 gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt tgaaaaagcg
    25141 ggattattca ttaatattga agattatttg tacttagctg taggtgatac agaattaaaa
    25201 tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg accatttggt
    25261 gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag ttccattgca
    25321 gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac gaaacaagat
    25381 gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac actaagtttc
    25441 cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc tagctttatc
    25501 gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa tgctgtagtc
    25561 aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt cgttctaacg
    25621 gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg ggaattgaca
    25681 ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac aaagcagctt
    25741 tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga aaatacaaga
    25801 ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga aagtgatgaa
    25861 tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa aatccaagaa
    25921 aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa aatattaaaa
    25981 atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa gttatcagct
    26041 gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa tcaagcagaa
    26101 cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga gcaagaacgt
    26161 tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga aatgtaaata
    26221 atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa attgccgtat
    26281 ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg ggctgggcaa
    26341 ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat gtgattgctg
    26401 aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat gttaagaccc
    26461 aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc ttagacttcc
    26521 aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac ccttatgatg
    26581 acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg ataaattatg
    26641 caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg aagccaggat
    26701 cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa gagcaaagga
    26761 aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct gtctataacg
    26821 ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg tatgatcatt
    26881 gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag tgtctggaat
    26941 cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat ggacacatca
    27001 gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca ctcttagata
    27061 atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta aacgtacatc
    27121 cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc aatcgctttg
    27181 atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat tatatctctc
    27241 acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt aaaggctatg
    27301 aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct gcagatcata
    27361 tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca actgcaagta
    27421 atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca gatgccctgt
    27481 ctagaagaaa catcaaagga agcgtatgtc ctggcagaat ttctggattt tatgagattg
    27541 cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag aatggctatg
    27601 aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca aattatgaaa
    27661 tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt gcagaataca
    27721 agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc aattattctc
    27781 gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc ttgaataacg
    27841 atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca cagtttgatc
    27901 gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag catgcaggag
    27961 tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat cgaacacatt
    28021 gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact gcagcttgta
    28081 tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca ttagaagtag
    28141 cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac aatgtctatg
    28201 cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa gatactccag
    28261 aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg ccagcatata
    28321 ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc gacttttcgt
    28381 tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg cacataacgg
    28441 ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa ataagtcgag
    28501 gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa ttgcttttca
    28561 aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac cgtttattcg
    28621 tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta ttcatgctca
    28681 gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg tcaaagaatc
    28741 gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt cctctacaaa
    28801 agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa ccagattgtt
    28861 cttagcgtca atataaagaa catttccact attaccaatt gctgaatata tttcgttctc
    28921 agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt ctaaagcact
    28981 ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt ttcctttata
    29041 catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg ataaacacaa
    29101 accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg ttttaggaga
    29161 cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat tgacatggtt
    29221 tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg ttagcttact
    29281 tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt tgaattcgcc
    29341 ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat cttcacttga
    29401 acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg ttagcaagtg
    29461 cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact ctggaaaata
    29521 atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa tgccaatcag
    29581 caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt ttttataacc
    29641 attccattca tctgtataaa cttctacccc atccttatat gcgacaattt gacatatatt
    29701 tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat attacctcac
    29761 tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat tcttcacgta
    29821 atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct gaaaaatata
    29881 aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct ttaatttacc
    29941 aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg tcttgattag
    30001 aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc ttataaacta
    30061 ggtttttaaa ggtgactatg gtaagataat agagatatta ttttgtgatt aggagtgtat
    30121 atatgaataa aaatggagaa tggagtgctg cacgacggat attcattata ttaatggatg
    30181 ttattgtata caatgcagca atatatagta gtttcttact gaagtttcgt ggagagatcc
    30241 cattacgaaa tttagaaact ttccaacact cagcaattat tatttcagtg atttttattg
    30301 cgttgaacat tttgttgggt gcatatgttt tttataatcg aatgatcagt gacatcgtgt
    30361 ttgtcacagt catcggtcag gtattgatga cactagggat catggtagtg acttttgcgg
    30421 gccgctggtt tgcttttcca cgtcttgtta tcttactttc atttgttctc ggtacgcttt
    30481 tcttaagtat ctatcgtatt ctcgtatata aactttattt acgcgtaagt cgagataaaa
    30541 aggtcgtcat tattgggtta gaaaaggatg tcgcaccagc aatccaaaat tttggttcaa
    30601 agaaaaacaa caaacataaa gtcgaagcag tcattcttga taactattat gcaaacatca
    30661 aaaatatgat taaagacatc gatattgtct atcttgcttc tcatatcgaa gaaactgaaa
    30721 aaatcaaaat ctatcaatta gttactaaaa atgaaaaaaa attgtttttg aatacaacat
    30781 ttgaaaactt gacattgatc aatccaaata ttatgaattt cgaagatgaa agtattattg
    30841 aagcatctgg atttagaatc caacctgaat atgaactatt caaacgtttg tttgatatca
    30901 tcgtttcact tgttttatta gttattgctt caccatttat gttattcaca gcaattttag
    30961 tcaaagtgac atcaccggga ccaatcatct ataaacaagt gcggatcaca aaaaatcaaa
    31021 aggaattttc aatctataaa ttccgctcga tgaccgccac agccgaagca aaatctggac
    31081 cagttttagc taagagcaat gatgcacgag taacgcctgt aggtaaattt attcgagctg
    31141 tccgctttga tgaattacca caaatcttca atgtgctgaa aggcgatatg tcgatcgtag
    31201 gaccacgtcc tgaacgtcct ttcttcgtcg atcagttcaa tgcagaaaac ccttattact
    31261 acttacggca taatgttcgt gctggtatca ctgggtatgc acaagtctat ggaaaatatg
    31321 tctctgatta caacagtaaa ttacgttttg atttacttta tatcaaaaaa tattcattga
    31381 tgcttgattt aaagatcttg ctgcaaacca tcaagatcct atttgataaa atgtcctctc
    31441 aaggacttga agaagacgaa aatgtgatct cattggcaga aattgctttt ccgaatgaaa
    31501 aaatctttcg ctagttggga ggcgtaaaaa tgaacaatcc gaaattcagc ataatcgtac
    31561 cagtatacaa tgcagaagca actattggtc gaacgattga tattctaaaa gaattggatt
    31621 atgaagagta cgaagtcgtt ttagtaaatg atggatcaac agatcaaaca caggaaatca
    31681 ttcaagaact gattgaaaat gatgaacgtt ttgaattgat tactacgacc aatcaagggc
    31741 ccggattagc aagaaacgaa ggaataagac agtcaaaagg agaatatctc ttattcttcg
    31801 atgcagatga cacgccagta aaaacgatct tgtcagatta tgatcatttg ctagaaaaga
    31861 gtccaaaagc ggatcttgtt gttagttcgt ttgtttttcg tacaatggac gagggaagaa
    31921 tcgtttccga aaaagaaaac ttagttacag aatgtcacta tctaactcac gaagagttta
    31981 taaaagacat gtatcagtta atgaatgaac agttgatgta tgttgtatgg aacaaatgct
    32041 atcgtagcga tattctgaaa aataaccaaa ttctatttaa aacttataat agttgtgagg
    32101 atcgaatatt taacttacat tattatgaat actgtcatca agtgatcatg aacccaaaag
    32161 tagaatatat ttatgaattt gaaggtggga aggggatcac taatcaatac cgacctaaca
    32221 agttcgaaac atttaaagaa ttctattcat tagcaaatac tgtaacagac gatattaata
    32281 aagacggtat ggcggcgctt cttttaaaag ggacaacttc agttattttt tctatttata
    32341 gtacctctgc aagaacttca aaagagaaga aagacgaagc aaagcagata ttgagtgatc
    32401 cagtgatccg agaagccaag caaattgcta agacggattc ttcagcaaaa aaaataacaa
    32461 agttgcttta caatatgcca gctccactat ttttatctgc tgtaaaagtt ggaagcttcg
    32521 ttgaagtgaa aatgccaggg ttaatggctg ctttgaagcg agtatattag ttaatggagg
    32581 aaaatataat gaaaagaatt ttgcattttc agggacgaat gggtttaggt ggagcagagt
    32641 ctttcatgat gaatttatat cgtaaaattg atcgtacaaa ctatcaattt gattttttga
    32701 tttatgaaga ttatgcagat gttcaagact atcattcaga gattgaaaga ttaggaggcc
    32761 gtatttttgt tgtacctaat cctaagaaaa atatttttaa atatttaata gaagtgaata
    32821 agttactaaa aaaagaatct ttttctatag ttcacaatca ggtttatttt ggcgggggaa
    32881 ttaatttatg gttagccaaa aagaatggaa tcagacagag aattgctcat agccatgcaa
    32941 ctgaagatgg aaaatctcaa aatattgtaa tgaatgtatt gcgtaaattt ttaaccaaat
    33001 tgttgttaca aaatgcaaca gactaccttg ccgttagtca agaagctggt gaaagtctgt
    33061 ttcaaaacca cccctttgag atagttcata atggtattga tttagagctt tatagtaaaa
    33121 attcagaagc taaggttaat aagagaaaag aattggatat ctcaatgagt acttttgttg
    33181 tgggaaacat tggacgatta gagaaacaaa aaaatcaatc ttatttgtta gagatttttt
    33241 tagaaatact aaaaatgaat tctgattctt acttgatttt agtaggtgaa gggtcactta
    33301 gaaataaact gaaagccaaa gcagtagaat tggatataga gaaaagagta aaatttttag
    33361 gagaaagaaa cgatattccc gagttattat ctgtgatgga tgtttttgta atgccttctc
    33421 tttatgaagg tctgccaatg gttggattag aagcacaagc agcaaaatta aaattagtct
    33481 tagcagatac tatttccaaa gatacaaagt taacaaataa tgtggatttt gtatcattag
    33541 atgaaacacc acaagaatgg gcaaaaaaag taataaaaga gccgtatgct aataaaataa
    33601 cacaagaact aaagagttat gatgtttcgt acactactga acaaatggag agtatatata
    33661 gtagagatca ttaaaaatgt tcaagatatt ttaggagtga ttatttttga aaatatgtta
    33721 tttgatattg gcatacaatg atattggcaa cttaaagaga ttggtcaatc gattgaacga
    33781 aaatgcagtt tttattattc atatagataa aaaaactgat atagaaccat ttattgaagc
    33841 atttaaatca tatgataatg ttgaattttt atgtaataaa aaccgtgtta aaatttattg
    33901 gggtggtttt tccattgtac aagcagaaat caatttagta aagagagcat tacaaaatga
    33961 gaaatattta aaatatgtat tattatctgg tgctgattat ccaatcaaag ataatgagta
    34021 tatttataat tattttaaaa agaatagttc agtggagttt attcgtggaa tagatctaga
    34081 tcaaattaaa cataaagaat tttattataa acatatagat gtatatcaaa aacatgatta
    34141 tcctagaatt aataggaata acacaactgc atttaaaatt tttagagcta taattaatcg
    34201 ttgtctgagg atgattaaac ttcccccaaa aattagacac cataaatttg atttgtatca
    34261 tggttctcaa tggtgggctt tgtcgaaaga atgcctaaca gaattaatac aaatgtatga
    34321 acaaaatcaa caagactacc tgaattttaa aataggtatg tttgccccag atgaaaaatt
    34381 ttttcataca ctttttttta attcctcgtt caaaaataaa aatgttattg gaggaccaga
    34441 tttaccactt gaattgaaaa atattgaaga aactacttta caaacttcga aattagcaaa
    34501 tattcatatt attgatcctt ccatgaacaa atggtttgat gaaagggata tagatcaaat
    34561 aaaagaaagt gaaaaattat ttgtaagaaa agttaaatcg gattactctg ataaactatt
    34621 aaatagaatt gataaagaaa ttttgaaagt tggaaatata gatgaataga atagtacctg
    34681 ttttagagaa gagtttatta agtcgagatg cgtttcgagt aataaattta atcatttgtc
    34741 tgctttattt tatgcctagt acttttaatg taactaatat cccgatgaaa atagcttttg
    34801 cttggggtgg aattatagtt ttgtatgagg tttttataaa gaaaaatttt tttaaaatgc
    34861 gtttttcttg gctactgatt ggagcaatga ttagttttat cttaactata atcattaaca
    34921 gagaaaattt tttaattcca tctatttata attttggata tttgctgatt actttgatag
    34981 taatttttcc tgcagacttt tcacaaagtg aagaggaaaa aaagaaaaaa atggtgtatt
    35041 ttaataatgt tttcattatc ataatttttt tagctgcgct aatatctatc tatcaattta
    35101 tttttttgat ttcttatcat gtcccaacag gaacgccagg attacttgca agacaaggtt
    35161 ttattgaaca tcggttattt ggtgtctata caagtccaaa tgttggagct atgtttggat
    35221 atacttctat tattttaagt ttaattagtg tattaatttc aaaaataaca aaaacgattc
    35281 gtgtttttta tatgatgaat tttatcgtac aaatatttta tattacactt tcttcgtcta
    35341 gaggtgccca ggtagtaatt tgttcttttt tagtattatt tcttttgttg tttgccaatt
    35401 caaaatttag aaagagcatt agagaagtac tacctgtaaa aatcaaatgg atggtaagca
    35461 tattattagt tctattggta tatttttctt ttggtactaa ttatgctaag gattttttag
    35521 caacaattcc tgtatcgatt gatagaaaag tagaagttat agagtcaaat gaatcagata
    35581 aaactccact tccagaaaaa gaagtaatat tacagcattc tagtgataac tccgaaattt
    35641 cagctggtcg ttttacgatt tggaaagctg cgcttaaagt tataagacca actttgttat
    35701 ttggttatgg agagaccgat ttctatggga atagcgatgc aaaatttttg aaaaaagtag
    35761 atcttgatac tacagatgtg aatgaactaa aaagagcaca tggaaacatg cataatggat
    35821 ttcttcaagt acttgtatca agtggtataa ttgcttttat atgtatctat gctttctatg
    35881 tgttaaatat ctttagttta ctcaaaacat tttttagaag taaagtgaat tatgcgtttc
    35941 ttggtattgt tttaattttt atactatcta tttttataga tgaaatggtg gaggctcatg
    36001 tacttttcaa taagcgcgat gtcatttcaa ttgttttctg gtattatttg ggaagcattt
    36061 cttacttgta tttaaaaaag gagaattaat atgaagacag ctttcattgc ttggactcct
    36121 ttacatttga ttaatatatt aaatgtttat caaaattttt accgagaatc aaaaggagat
    36181 ttatttattt attctgaatt tgaaaacgct agaagatata gtgagcgtat aaaagaatta
    36241 gggctattta atgatgttgt ttttgtgaat caccggaaaa tcggttcttc ctttaaacgt
    36301 aaaattaact tgttaactaa ccataatcaa tttttctcgg atgatttatc cgtttatgat
    36361 gaaattttta tacaggggga aaattatttc acaaaaatac ttttctccaa tgtttacaaa
    36421 aaaaatccag atgtaaaact aaattatata gaagatggtt tgggtactta tttgaagaag
    36481 agtatatttt caacaagtaa aaacgttcaa agagttttta aaatattaaa taaaaatagc
    36541 atcttcaaaa aaaaaattga cgattatttt gtctattgtc cggaattgtt actttatgat
    36601 gtaaaaaata taaaaaaaat tcccaaaata gatgaaaaca gtaaattgat gaaaaacata
    36661 caatcaatct ttgggataga agaagttttt gtcggagata aatgtatctt ttttgatcaa
    36721 cctttattat ctgatggtta tggcatagat gaaacagata ttttcgctaa agtaaatagt
    36781 atattttctg gaaaaaaaga aactttaatt aagcttcatc ctagagcaag gacaaatcgt
    36841 tatggtgaaa aaaacatatt gaattccagt ttaccgtttg aagtcttgct acttgaaaat
    36901 gacttctctt caacactttt gattagtcct atatctacaa tttctttttc accatctatg
    36961 atgtttgaaa agacgatcaa ctctattatg ttggctaaat taattttaaa tgaatataca
    37021 gcattatctg aagataaaaa agaaacattg acaaatattg ttcttttctg tgaacattat
    37081 aaccgtctat cagaagaaaa aattttactc ccagaaaact gggcagaatt aagaaagttg
    37141 gtagagtatg ggattattta acacactttc caagtcaaaa ttagttaagt ccagtttctg
    37201 gtatactata gggaattttt ttattaaggg aatttcattc ataactattc ctatttttgt
    37261 aaatattact actcaagcag aatatggttt gattaataat ttcacttcat ttgtatcaat
    37321 tttttcgatt cttgttgggc taagcctaaa ttcggcaatt aataatgcaa gttttgacta
    37381 taaagatgac ataaatgaat ttatgtcatc ggtactttct ctagctacac tttcgttaat
    37441 tgtgttctta ttaataggga acatatattt tttgttttca aatgcttttt ttgatatgaa
    37501 ccaacttgta tttaatttga tgttattaca aagttttgct agttttgtaa ttagttatat
    37561 ccagtcttat tttacgatta actttaacca ttttaaatat ttgattttat cttttatatc
    37621 tacttttttg aatattgcaa tctctgtagc tttgatgcag acattatatt ttgatgataa
    37681 atatgttggc agagtagtcg gcggaacact gtcatttgtg ttgataggtt tagtaattta
    37741 tttaagaata atgataaagg gtgctcattt ttttgataaa aaacagtgga gatacgcttt
    37801 aaaaatctct ttgccgctaa tcccacattc cttagcaaat atagttttag cacaattcga
    37861 tagaattatg attaattctt atttaggtcc tgctgcgggg ggaatatatt cctacattag
    37921 taacataggt attattctaa gcgtaatatg gatgtctact aataacgcct gggttccatg
    37981 gttctatggt gagatgagta aaaataatga aaaaaaagtg aagaaagtta gtaactatta
    38041 tttagtagtc tttactttga ttacgatgat tgtaatggta gtttcgattg atttagcaaa
    38101 atttatggct ccgaaagact attattctgg gttatcttta gtggttccga taaccttagg
    38161 ctatttcttt cagtttttat atagtttacc agttaatgct gaattttatg agaaaaaaac
    38221 atcgtttatt gcgattggta cagtagcaag tgctatagtt aatatactat taaacatgat
    38281 tttcatacct aggttaggaa taattgctgc tggatacaca accgtattta cgtatttttt
    38341 actttttatt tttcattata atatcgctaa aaaaattacg aataaacaat tatttgacac
    38401 aaaaaaaata tgtatcataa taatttttgt atcaattttt tctttgatac ttcatatttt
    38461 aatcaatcaa atgttgattc gttacgtttt gacatcatta ttgataatta gtttagttat
    38521 atatttttta aagattaaga atcgaattat agatgactat aattcatagg aggagatata
    38581 agtgtttaaa ggaaaaacaa tattagtaac tggcggaact ggttccattg gaagtgaaat
    38641 tgttcgtcag cttttaaaat atgaaccaaa agctatcaga atttatagta gaggtgaaga
    38701 aaaacaattt tatatgcaac aagagctctc aaatcacact aatttgagat ttttaattgg
    38761 tgatatcaga gactctcaaa ggattgatta tgcatgtcgt gatgtggata ttatttttca
    38821 tgctgccgca atgaaacacg ttccagcaag tgaatataat cctatggaag ctgtaaaaac
    38881 aaatgtgatg ggaactcaaa atgtaataga tgcagcgatc aaaaataatg taaaacattt
    38941 tgtaggtatc agtacagata aagtagtgag tcctactaac accatgggtg cgacaaagtt
    39001 attgagtgaa aaattaataa tagctgccaa tcagtataaa ggaaaaacag aaacaatatt
    39061 ttcttgtgta aggtttggaa atgtcatggg gtcaagtgga tctgttattc ctctttttag
    39121 taaacaaata aaaaacaata aagatattac tttgacagat gttgatatga cacgatttat
    39181 gatgtcaata ccggatgctg caagattagt tctgtctgct gctatgaatt caaaatttgg
    39241 agaaacatat gtcttaaaaa tgccggcaat caatatttta actttagctc aatcattaat
    39301 aaaaatatat aatgatacac atgatgaaaa atatagaggt gaaataaaag ttgtaggtat
    39361 caggccagga gaaaaattat atgaagagct aatgactaca gacgaaattg aacgctcata
    39421 tgaaaatgat aaaatgtata tcattccacc acactatcat gctactgacg aactgtacaa
    39481 agattatgaa aaaattaaaa tcactgcata ctcttcagat gcaacagaat taatgagtgg
    39541 acaggaattt attagaatcg caaaagagaa taatgtcgtg acttggtaag gagttttatg
    39601 atgaaatcag aagtatatgt aattgcagaa attggtgtaa accataatgg aagtctagat
    39661 ttagctttag aaagtattga taaagctaaa gaatgtggag ctaacgcggt taaatttcaa
    39721 acatttaaaa cgaataagct agtttccaaa aaggctccaa tggcaaaata tcagaaggat
    39781 aatcttaaag aggacagttc tcaatttgaa atgctaaaaa aattagaatt atctcaatct
    39841 gattttatta gaataaaaga ttattgtata caaaataaaa ttgatttttt gtctactcct
    39901 tttgatgaag aaagtgcaga ctttctaaaa caaattggtg tacaaggatt taaaattggc
    39961 tcaggagatt taacaaattt accttttctt agaaaaatag atatgtatgg gttgccagtt
    40021 ttattatcta caggtatggc tgatattcat gaggtcagtg aggctgtaga ttgtttcata
    40081 gatagtccag ttactatttt acattgtact tcaaattatc cggctagttc tgaagatatt
    40141 aatttattgg cgattaacac attaaaagaa atgttcggga tacccgttgg gtactccgat
    40201 cattcattgg gatatgatgt tggtatttgt gctgttgcga tgggtgctaa ggtaattgag
    40261 aaacatttta ccttggataa ggaactacct ggtccagatc ataaagcttc tttagatcct
    40321 caggaatttg cagattttgt aaagcatatt agaaacactg aaatattttt aggtgatggt
    40381 gttaagcgag caatgccttc tgaacttagt acaaaagaag tatcaagaaa aagcctagtg
    40441 gtcactgaga atttaaatgt gggagatatt cttacagaga aatctcttac aataaaacgt
    40501 cctggaaatg gaatagctcc taagttttta tatcaatata ttggcaaaaa agttaaaaga
    40561 ccaataagtg cagatagtgt tctgcttgag gaagatgttg aatgaaaaaa atacttatag
    40621 taagtggaac acgagctgat tatggaatat ataaacctgt tgctgagaat ttactacaag
    40681 ataattggga tgtatcattt gttgtttctg gaatgcattt atcccataaa tatggattta
    40741 ctaaagaatt gatcttagct gacggattta gaattagtgg agaagttcaa agtttgtttt
    40801 tagagaacaa taagggaaac atggctcggt ctgtggcatt agagataaat ggtttcacaa
    40861 atatatttga acaaactagc cctgattttg tattattact aggggataga ggagaaatgt
    40921 tggcagctgc gatagcttgt ttgtatcttg gaatcaaaac agcacatatt cacggaggcg
    40981 aagtgtctgg tactgtagat gaatcaataa gacatgccat aacgaaaata gcatctgttc
    41041 attttgctgc tacggaaaaa agcaaagagc gtttaataaa aatgggggaa gattcttgga
    41101 gagtttttcc cgtcggagct cctagaatag atactatttt aaataataga ttacctagtt
    41161 ttagagatat aaaagaaaaa tatcatctaa aatttgaaaa gaaaaaatac gttttgcaag
    41221 tatttcatcc agttgtaacc gaactagaaa atatagaaaa acaaatttta gctttgatca
    41281 attcaatgga acaacaatct caaccaatta tttgcatttt acctaatagt gatgctggta
    41341 gcgaaattat cagaaaaatg taccagaaat atttaaaaac ggatattatt tatattacga
    41401 atttagagcc ggaggaatac ctgactatat taaaagagtg caaatttatg atcggaaatt
    41461 cttcttctgg gataattgaa gctgcatcat tcaaaatacc agtaataaat ttaggaacca
    41521 gacaaaatgg acgagaacaa tctaaaaata ttataaatgc aaatctaaat gaaaatgaaa
    41581 ttgaaactgc tttgaataaa atacaagatc ctcagtttat aaaaagcttg aaaaatgtta
    41641 agaacatcta cggtgacggc aacagttcta gaagaataac aaaaacattg aatcaaatat
    41701 tgaatgatgg ggaagatatt aagtggattc aaaaacaaat agcttattaa aatatactag
    41761 tgatccatac attattattg gggctggcgg acacgcaaaa gtcattattg aaaccttaag
    41821 attagaaaat aagttaatat atggattttt tgatgataag caaaataaaa tgcaagatct
    41881 gaaatatctt gggaaaataa acgaattgaa tagctgggcg gatagcaaaa aaaaaatcta
    41941 taaatttatt gtagctattg gtgactgtgt agtaagaaaa aagattataa aaaaattgaa
    42001 tatgccaagt gagcaatatg gaatagctgt tcatccaagt gctatagtgg caaaagaaat
    42061 ttcaattggt tatggaactg ttatttttgc gaatgctgta attaacccag atgctgtaat
    42121 tggagagcat gctataataa acacaggtag cattgttgag catgattgta gaattaataa
    42181 ctatgttcat ttatctccag gtgtatgctt agcgggtgga gtacatgtag gtgtaggaac
    42241 tcaaatagga attggttctc aatgtatcca gatgaagaaa attggatctt ggtgtatgat
    42301 aggcgcaggg agcactattg ttaaggatat tccctcacat tccttagctt atggcaatcc
    42361 agctaaaatt aagaaagaag gaattaattt tgaattctag aattttatta tcaagtcctc
    42421 atatgggagg aacagaagaa aaatatgttg ctaaggcttt taaagataat tggatagcgc
    42481 cattaggtga aaatgtggat aaatttgaag aaagtattac aaaatatact ggttctaagg
    42541 gcggagcttc tgcgttaagt tcaggtacag ctgccataca tcttgcctta agactgctta
    42601 atgttggaaa aaacgatatt gtctttgctc cttcatttac ttttatagct acagtaaatc
    42661 ctattttata tcaaggggct gtaccagtgt tcattgactc agaacctaat acatggaata
    42721 tgagccctgt tgcactagag agcgcattag aagaagctga aagaaacaac caattaccta
    42781 aggcaatcat cgtagtgaat ttatatggtc aaatggctga ttatgaacga attttagcta
    42841 ttgcaaacca atttaatgtt ccagtgatag aagatgcagc ggaatcgtta ggttctactt
    42901 ataagggaat ttcgtcaggc ttatttggga caattgggat ctattcattt aacggtaata
    42961 agatcatcac aacctcaggt ggaggagctc tagtgtctag tgataaaaaa tatgttgagc
    43021 attcaagatt tttagcaaca caagcaagag atcaagcacc gtattatcaa catagcgaaa
    43081 taggttataa ttaccgtcta agcaatattt ctgccggtat cggacgtgga caaatggaag
    43141 tattgaatga tagagtagct aaacgaagag aaattttcaa tcgatataag gaagcttttt
    43201 ctggaattga tagaattgaa atgatgccag aagtggatgg catggtgcca aatcgttggt
    43261 tgtctacttt aacgatcaat gattataatt ctattgatca agtagttaac gtaataaata
    43321 aactaaatga aaaaaacatt gaaacaagag ctttgtggaa accactacat ttgcaaccag
    43381 tatttcaagg ggtaaaaatg tattaccatg ataataatct tagtgtgtca gaaaagttat
    43441 ttaatagcgg cttatgctta ccttctggaa gtaatatgac agatagtgaa caagaatttg
    43501 ttattgatga gtttaaaaaa atattcaagt aggtgtgata ttttatgaac ataggaatta
    43561 ttggtttagg ttccatgggg aaaagaagac ttagactcat tcaagaacac tttaatgata
    43621 ttttactatg tggtgttgat actaatgagg cgagacgaaa ggaagttgaa aaggaatttg
    43681 gaataccaac ttataatagt ctaacagagg caaaaaattt gtttgaaata aattcagttt
    43741 ttgtttgtac atcccctata acccatgaat ttattataaa agaggcttta aatttagatt
    43801 gtaatatctt tacggaaatc aatttattaa atgaatatta tgatgaaata atcgaagtag
    43861 ctaaaaagaa agatagatta ctttatctat cttctacatt tttgaagaga aaagaaattc
    43921 aatatattaa gtctaaagtg acgcataata aaaaaatttc ttatcaatac catgtaggac
    43981 agtatttacc cgactggcat ccttgggaag attatcgcaa tttttttgtt tcaaacaaaa
    44041 aaactaatgg gtgtagagaa atattcgcta ttgaattacc ttggattata gatacatttg
    44101 ggaaagttaa atcgtttact gtaatgaccc agaaattatc caatcttgat attgattatt
    44161 cggacagttt cactcttatt attgagcatg aaactggtat agttggaact ttaagtgtag
    44221 atgttgtttc aagagtagct aaaagaaatt taactataat tggtgaaaag attttaatag
    44281 aatgggaagg taacccggat tctctatttt catggaatga agaaacttct agtatgacag
    44341 atattcaatt gtacgatgag gttatgcatg ataataatta ttcacatact attattgaag
    44401 atgcatattt agaggagatt aaagaatttt tcacgctttt ggaaaagaaa atggaacccc
    44461 aatatacttt tgaaaaagat aagtatatta ttaacttaat taacgacatt gaggtaaatt
    44521 aatgatgaaa gtaatttttt ttgggttagg gtcaattgga aagagacatc taaaaaatct
    44581 aataagctat ggaaaaaaga attctattaa ttttgatata acagcttata gtagcagtgg
    44641 aaaaaaagag tttgaagaaa taacgtatat tcaaaataga gacgatttgg atacacatta
    44701 tgatatagct tttattacaa atccgacttt taagcatctg gaaacactaa atgtaattgt
    44761 tgaaaaagtt gattacatat ttttagaaaa acctgctttt tctgagagta ttgatcttac
    44821 tcaatataat tatgattaca aaaatattta tgttgctgct ccactgaggt ataaaaatat
    44881 catggaagtt gttcgtaata gtattcaaag taaaaaagta tattctgtaa gagctatttg
    44941 ttctacttat cttcctgatt ggagaaaagg tactgattat agaaataatt attctgcctt
    45001 taaatctatg gggggaggag tagaattaga ctgtatacat gaattggatt atattataaa
    45061 cctatttggt ttccctaaat cagtaaaaaa acagtttggt aaatattcga atcttgaaat
    45121 taacagtaat gatttagcaa catatatatt gagatacgat gataaaatta tagaaattca
    45181 tttagattat tttggaagag ttcctacaag aaaatttcaa ttgtttactt tagatgaatg
    45241 tatcaatgtt gacttattaa ataataaaat aagttttgaa gaaaacattg ttaaagaaat
    45301 gcctgaatct gctaatgata tgtatgagaa ggagttgaaa tatttctttg aaaacgtagt
    45361 aacaggcaaa gaaaactgga atgatttata tcatgcaaac gaagtattga aaatagctga
    45421 ggagaaataa atggaaattt tatttactat ttgtggtaga gctgggtcta aggggtttaa
    45481 aaataaaaat ttgaaatatt tggcaggaaa gcccctagtc catttcgctt tagcaatgat
    45541 agatatctat caacaaaaac atcctgaaca taattgcacg acttgtttga atacggacag
    45601 taatgagtta gtagaattga cgactaagtt aaatccgtct gtgaaaattg tagaacgtaa
    45661 acctgaatta gctacagata ctgtagggaa aattgaagtg atacgtgatt cattcttaca
    45721 actagaaaga gaagataata tatttgattt aattatagat ttagatttga cttcaccttt
    45781 acgtgaagtt tctaatcttg aagaattaat agatgaacat ctaaaaaatt tagataaaga
    45841 cgtctacttt tcagttgttt ctgcaagacg taatccctat tttaatatgg taaaaagaat
    45901 tgaaaatgaa gttactatag ttaataaatc aagatacaca tctaggcaac agacacctga
    45961 agtttttgaa atgaatgcct caatgtattc ttttaaacct gaatttctaa aaaaaagtaa
    46021 ttatattttt gatgggcaat gtgggataat aaaaatgaga gattatctaa ttttagatat
    46081 tgatagtgaa gaagatttta aatggttaga atttttgttt cctaaatttt tagaagattc
    46141 ttcggagctt caagatatct ataattattt atatcggagg taaaaggatg agctgttatc
    46201 ttatcaccgg tggggctggc ttcattggtt ctaccttagc caatcattta ggagaagaac
    46261 atgtggtaat cgtcgtcgat gacttatcaa tgggaaaagt agaaaatctt gatatgacga
    46321 aaaatatcac ttttattgag ggagatgtcg ctgagaaatc cttgatggaa gagatcatga
    46381 aagctaataa atttgattat atctttcatt tagcagcagt tgctagtgtg gcagattcag
    46441 ttgcccgacc agtagaaaca catcgtgtga attttgaaag tgtattaatg attttagaat
    46501 tgatccgcaa gtatcaacct gatttaaaac ggatcgtgtt tagttcttca gcggctgttt
    46561 atggggatga accgacttta ccaaaaaaag aagagtccgt gattcgccca ttgacgcctt
    46621 atgcggttga taaattcgct gcagaacaat atgtgctaga ttattgtcat ttatatgatg
    46681 tacccggtag cgcagttcgt tttttcaatg tctatggtcc aaatcaaaat ccgaattctc
    46741 catacagtgg tgtgatttct attctcgtag atcgctataa taaacaaatc gtaggagaag
    46801 caacttcatt tacattattt ggtgatggaa gccagtctag agactttgtt tatatagatg
    46861 atgtaatcca agcattactt ttagttgcga atgaggaagc tgcactgggg aaacaattca
    46921 atgttggaac gggtaaagca accacacttt tggaattgat tcatgcaatc aatgaaattc
    46981 tcggtgtaga attgacactt gaatacaaag aagagcgttc gggtgatatc catgactctc
    47041 tagcagatat tactaagatc cagtcaattg gctatcaacc gaaatatggt attttaagtg
    47101 gaatgactaa ttatttgaaa actgaaatca attaaaacat actaagataa gattagaggg
    47161 taaattcagg ctctttgtca ataaggactg atgagttttg taaaatcaaa tctgggatag
    47221 aa
//
LOCUS       DAIGWC010000013        45291 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.013, whole genome shotgun sequence.
ACCESSION   DAIGWC010000013 DAIGWC010000000
VERSION     DAIGWC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.013"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(105..629)
                     /locus_tag="NOB74_000762"
     CDS             complement(105..629)
                     /locus_tag="NOB74_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1219968.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="NOB74_000763"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="NOB74_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HCI1219969.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="NOB74_000764"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="NOB74_000764"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HCI1219970.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="NOB74_000765"
     CDS             complement(2351..3031)
                     /locus_tag="NOB74_000765"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCI1219971.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="NOB74_000766"
     CDS             3157..4026
                     /locus_tag="NOB74_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1219972.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="NOB74_000767"
     CDS             4052..4567
                     /locus_tag="NOB74_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219973.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5207)
                     /locus_tag="NOB74_000768"
     CDS             complement(4614..5207)
                     /locus_tag="NOB74_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1219974.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="NOB74_000769"
     CDS             complement(5232..5411)
                     /locus_tag="NOB74_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219975.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="NOB74_000770"
     CDS             complement(5488..5997)
                     /locus_tag="NOB74_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219976.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="NOB74_000771"
     CDS             complement(6093..6473)
                     /locus_tag="NOB74_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI1219977.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="NOB74_000772"
     CDS             6803..7552
                     /locus_tag="NOB74_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HCI1219978.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7873..9090)
                     /locus_tag="NOB74_000773"
     CDS             complement(7873..9090)
                     /locus_tag="NOB74_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI1219979.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(9348..10625)
                     /locus_tag="NOB74_000774"
     CDS             complement(9348..10625)
                     /locus_tag="NOB74_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1219980.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(10704..11348)
                     /gene="pcp"
                     /locus_tag="NOB74_000775"
     CDS             complement(10704..11348)
                     /gene="pcp"
                     /locus_tag="NOB74_000775"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HCI1219981.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(11547..12491)
                     /locus_tag="NOB74_000776"
     CDS             complement(11547..12491)
                     /locus_tag="NOB74_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HCI1219982.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(12493..13179)
                     /locus_tag="NOB74_000777"
     CDS             complement(12493..13179)
                     /locus_tag="NOB74_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HCI1219983.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            13653..13973
                     /locus_tag="NOB74_000778"
     CDS             13653..13973
                     /locus_tag="NOB74_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HCI1219984.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            14127..15032
                     /locus_tag="NOB74_000779"
     CDS             14127..15032
                     /locus_tag="NOB74_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1219985.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            15029..15802
                     /locus_tag="NOB74_000780"
     CDS             15029..15802
                     /locus_tag="NOB74_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI1219986.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15983..17407)
                     /locus_tag="NOB74_000781"
     CDS             complement(15983..17407)
                     /locus_tag="NOB74_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1219987.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            17618..18064
                     /gene="nrdI"
                     /locus_tag="NOB74_000782"
     CDS             17618..18064
                     /gene="nrdI"
                     /locus_tag="NOB74_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCI1219988.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(18129..20111)
                     /locus_tag="NOB74_000783"
     CDS             complement(18129..20111)
                     /locus_tag="NOB74_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1219989.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(20125..21021)
                     /gene="murQ"
                     /locus_tag="NOB74_000784"
     CDS             complement(20125..21021)
                     /gene="murQ"
                     /locus_tag="NOB74_000784"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCI1219990.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(21024..22085)
                     /locus_tag="NOB74_000785"
     CDS             complement(21024..22085)
                     /locus_tag="NOB74_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI1219991.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(22296..22862)
                     /locus_tag="NOB74_000786"
     CDS             complement(22296..22862)
                     /locus_tag="NOB74_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI1219992.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(22890..24392)
                     /gene="eat(A)"
                     /locus_tag="NOB74_000787"
     CDS             complement(22890..24392)
                     /gene="eat(A)"
                     /locus_tag="NOB74_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCI1219993.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(24650..25771)
                     /locus_tag="NOB74_000788"
     CDS             complement(24650..25771)
                     /locus_tag="NOB74_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI1219994.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            25897..26838
                     /locus_tag="NOB74_000789"
     CDS             25897..26838
                     /locus_tag="NOB74_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI1219995.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(26988..27884)
                     /locus_tag="NOB74_000790"
     CDS             complement(26988..27884)
                     /locus_tag="NOB74_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCI1219996.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            28153..29493
                     /locus_tag="NOB74_000791"
     CDS             28153..29493
                     /locus_tag="NOB74_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1219997.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            29711..30154
                     /locus_tag="NOB74_000792"
     CDS             29711..30154
                     /locus_tag="NOB74_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HCI1219998.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(30658..32076)
                     /gene="nhaC"
                     /locus_tag="NOB74_000793"
     CDS             complement(30658..32076)
                     /gene="nhaC"
                     /locus_tag="NOB74_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCI1219999.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(32479..33702)
                     /locus_tag="NOB74_000794"
     CDS             complement(32479..33702)
                     /locus_tag="NOB74_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCI1220000.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(33733..34572)
                     /locus_tag="NOB74_000795"
     CDS             complement(33733..34572)
                     /locus_tag="NOB74_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI1220001.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(34589..35269)
                     /locus_tag="NOB74_000796"
     CDS             complement(34589..35269)
                     /locus_tag="NOB74_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220002.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(35271..36344)
                     /locus_tag="NOB74_000797"
     CDS             complement(35271..36344)
                     /locus_tag="NOB74_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1220003.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(36400..36638)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(36681..36914)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(36991..37662)
                     /locus_tag="NOB74_000798"
     CDS             complement(36991..37662)
                     /locus_tag="NOB74_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI1220004.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(37749..40427)
                     /gene="mgtA"
                     /locus_tag="NOB74_000799"
     CDS             complement(37749..40427)
                     /gene="mgtA"
                     /locus_tag="NOB74_000799"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCI1220005.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            41086..41523
                     /gene="ndk"
                     /locus_tag="NOB74_000800"
     CDS             41086..41523
                     /gene="ndk"
                     /locus_tag="NOB74_000800"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HCI1220006.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(41545..42411)
                     /locus_tag="NOB74_000801"
     CDS             complement(41545..42411)
                     /locus_tag="NOB74_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1220007.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(42571..44664)
                     /locus_tag="NOB74_000802"
     CDS             complement(42571..44664)
                     /locus_tag="NOB74_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI1220008.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT        13056 a         9454 c         8063 g        14718 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct atttcctacg
     7741 attagtcaag taaaaggtgc aagaaaaata gctcgtaaac gaaagcgaca aaatcaaagc
     7801 acaccaaata aagccccgtt cgtaaaaaat tttcgatctg ggcaaagaag tggtatactg
     7861 taagtggttt agttaatggt ccactgagac cgcgtacgca tagtcgtact ctgtatgtgc
     7921 cctaaccata gcgtgcatac atttcagaag cttgttcata caagcaactg tggcaacctt
     7981 atctttctta gggataggtt gcttttttaa tttgtagtaa taatcgacaa tatgattagg
     8041 agctgcgcgt tgctggcgaa tcatatttcg aatggtgaag aaaataattt tccgtgcttt
     8101 gggattacca cgcttattga tgcggtcttg gccagtatac ttacctgaat gataccgtcg
     8161 gatgtcgatt ccgacaaagg cattcaattg tttatgggtt ttaaatcgtg tgatatctcc
     8221 taattcaccg agcaataaag cggctgtgag tgcgccaatc ccagggaacg tttggtacaa
     8281 caaaaagcaa ggagagcctt cggctttttt gatcatttgt gtcgccagtg cttttttttg
     8341 ttcgagtaaa tcttggagaa gttcggcgta atagatcgtt ttttgacagt ggatactgtc
     8401 tttttcaaca gctggatagg cacactgtgc atagtggatg atttgatctg ccttttgctc
     8461 ggcacgattc gcggagattt ttttccgtgt ttcgttgatc agtttatttt ttatttttgt
     8521 ccgagtagat gccaatacaa aatctggatg gggaaaaaga cggatcaatg tcaatgcgta
     8581 aggggtcagc ctgtttgaaa agaactgttc aagctctgga aaagtcaatt gaaggcagtt
     8641 gtgtaaatcc atgcgcagac gagtgatttt cttctcaatt tcttgataaa aacgggctaa
     8701 atcgcgcatc tctaagtaaa aattgctttg tacttctttt ggctgacgtt gatttttaag
     8761 atgagtctgt gcgagccggt gggcatccga tttatctgtt ttccaactgc gtaaggtgct
     8821 ttcttccatc tgttttttcg cctctaacgg gtttaacaaa cagtaagaaa agtgatgatc
     8881 ttgaaagaac ttttcgactg gtctggaata aatccccgtt gcttcaaaaa caatcaatgg
     8941 acgctcaggc aagtgctgga tctcttcgag taatgcatga aatcctcttt gagtgtgttc
     9001 aatctcgtct tcaaataagc aggtgtcgtc tttgtatagg acactgtagc tgtgtcccat
     9061 tgaaacatct aatgcaagaa tgtaaggcat ttgttttcct cctttttaag ttttgaaaga
     9121 actttactgc ttcatttcga ttccaatttc ctatacacgg gctcatggcc ccaacatacg
     9181 taaacctgat tctaaaatga cagtaaagaa gttcggtttt tgatagggac tcgtagtcct
     9241 caaggctttg ttcgaacttt ctttcactct tcactataat ctaaaaatag aaaatagagg
     9301 agaacatcat tcgtcaatga tgttcccctc taatcttagt atgtttttta tagtaattcc
     9361 ttcagatact ttcttgcctc atcattgaaa cgcagtgatt cttctaactt ctgataatat
     9421 tccaacgctt gtttctgagc ttcagtaaaa cgataatgtt ttcctttcca tttgtcgatt
     9481 gtctcttgca catttccaga ttggatatct ttcactacta gttgccattt ttcttttgag
     9541 actgtacggt ctttcttatc agcagattgt atagcttctc gttctttacg caatactttt
     9601 aaaaaaccat ttctgactat ccgaggaatg ctgtcgaaga acccttctgt aaaaccatag
     9661 cgacaatatt gcttccaaat aaatagatag atttttggtt ggatgaatcg ttggtttttc
     9721 gcaaaatatt ccatctgagc agtgacttct ggtgttcgtt gacgttttgt ctttctcaac
     9781 acggaaataa atgtttcaaa ataagcatta ggatgtactg gcacttcttc atatacgatg
     9841 gattgccaat ctttacgtaa aaatgcgcga tagttgatca agaattcttc tacatccttt
     9901 actaattctt ctgcaaagtc gtcaaatagt tcttttttta tctgtcgctt ttttgactgc
     9961 ccattgatgt gttcacttat tttcttgatt tcattttcca atgcttgata atccgctatg
    10021 taaatcggca tttctacttg gcgaaattct gcgagccgct gagctaattt tatatccggt
    10081 aaatatggct gtttcatccg acgattttgg tacaagacaa aacagtattt ttgccatagt
    10141 ccttcaggaa aatcgatatt cttctgctta agccataata attcgtctaa ggccagatca
    10201 acttttgtca ttccctgatg gatcgaagct gccactgtcg gagagacatg caggtgatcg
    10261 gcaaagtggt tgatgcctag ttttaggatc tttccggttt ttggcgattt aacgatgtat
    10321 tgcactttta attctctacc acactcacaa tacaattttt gctggcttcg ttttgttcga
    10381 aaaaacggat tgatcttgaa gtcagaaaac acccaatctg ttgcagctaa ataatgttct
    10441 tccataaaac gagagctgat tagatatcgg cggtgcttat cgactagttc ccgctgtttt
    10501 ttcgttaatt ttgcatagat ctcccaacgt tgactgcttg tgtattgttt agaaattttg
    10561 atgggatagc ttttgctgat ttcttttgga aaccattctt caaagacgga ttgccattct
    10621 tccacggctg tttctttcct ttctaattac aaaaagctgg ctactaacat aacgttagca
    10681 accagccagt gtttcttgct aaattagtga gttgttccgg catttccgga aatatcttct
    10741 ttattttcta ctgctgcttc aactgcataa gtcaaagaag aagcaatgtc ttctaaagac
    10801 atagaaggcg tacccactgg acgatcgatc acttgatcgg gtgagaatgg cacgtggatg
    10861 aacccacctc gaattgccgg gaattgtgtt tcgatcaaat gaagcaaacg atacatgata
    10921 tcattgcaga caaatgttcc tgctgtataa gagatgtacg ctggtagacc atgatcttgt
    10981 acattttttg tcattgcttt gattggcaat gaggtaaagt aagcggctgg accgttttct
    11041 tctaaagccg tatcgaatgg ctgatttcct tcattatcag ggattcttgc ttctgctaga
    11101 ttgattgcga cacgttcgaa cgagactgct gaccgcccac ctgcttgtcc gacacagatc
    11161 acgacatctg gttggtgctg ttggatggct tctttgacta cttgactgct tttttcgaat
    11221 acggtcggta cttccacttt gatgatttca gcaccgctga tttcatctgg catttttttt
    11281 actgcttcat aggctggatt cactttgtcc ccaccaaatg gatcaaaacc tgttactagt
    11341 actttcatct gttgttcctc cgtccgattg atttaacata tggttatctt ttatcatacc
    11401 attttccttg aacagcgtaa ataaaggaaa caatagttta aataacataa cagatcaaac
    11461 ttaatatatt cttataaaaa aatagtgttc cactacaatg ttagaagagg ttgcgacaat
    11521 tattctgtca caacccctct cttctattat ttaaatagaa tcatataagc aatttggaaa
    11581 actagcataa ataacgcaat aaacaactgg tttttgatca ctccgtattt gtctttcatc
    11641 tccagcatcg ctacaggcac gatattgaag ttagcagcca tcggtgtcag cagggtccca
    11701 caaaaaccgc aagtcaatgc aaccattcct attaacgctg gattcgctcc atgactaaat
    11761 acgaatggtg caccgatccc aaccgtcatc acggtgatgg ccgcaaatgc attccccatg
    11821 attaccgtaa atatcaccat gccaagagcg taaatgatga tgccgatgtt cacatttcct
    11881 tctggaacga tcgtacctac tgcattggaa atcactgtcc caactccagc gcttgtaaat
    11941 accgcaccta gagaagctaa aagcattggc aacatgctta acggccctac tgtgcccagc
    12001 atatctgctg catcatctaa aaatgtactt ggtcgattat ctcgagaaaa gaacatcaag
    12061 attagcatgg ctgcaaaaac accgacgccc acgccgacta aagcacctaa attggtaaat
    12121 agagcaaaca agatcgcaaa gacaccgata ctcaaagctg gaataaaaat tttcattcct
    12181 agtttgtctg acattttttc catatattct tttgatggaa gccggctttc tcctttgctg
    12241 actttcttag caattgctgg tatggtcatc gcaaagatca agccaccgtt cacgattgcc
    12301 ggaagccatc ttcctcctgc aataactacc cctaagaccg tccagaaaaa ggctgaccca
    12361 taacgatgag gattggtttt atctgttaaa tttcttactc cagtgtaaat caatacgagt
    12421 cccatcacga tataaaggat ctccagtaat ttatcgccta ataaaatatc aggatttgta
    12481 aaaaagtcca tcttattgcc cctttcctgg ataatatttc ttcgctaatt tcttttcttt
    12541 aagatagaag tagacacttg ccacaactaa agccgtgata gccactggaa cttccactaa
    12601 agcaagctgt cccaatgtta cgtcatatcc tagatctttc agtgttgatt ggactagcaa
    12661 cgcccctgct cctccgatga atagtacttg gccaaagaac cagcagacat tttccatagc
    12721 tgaagccata ccttttagtt cttcttcatg cttaggatgg acttctaacc cttttgattc
    12781 gatggtcccc aatgccatcg gtaaaatgat tggacgaaca aatccagcaa ctccaccaaa
    12841 actcacgtta aaagccgcaa agatcattcg aaagatccca taaatatcta caatcatacc
    12901 agcagatact ttcttgaatc gcttgatcaa ggaagccgct gattctttca gaccatttct
    12961 ttcaagcgtt cctgttgcca acataatgat gataaaaatc gccatcccgc gattgtttac
    13021 aaaacttgta cctaaaagtt ctaacattcc ttgaatgcca agaccgccag tcaaagctgt
    13081 aacaactaaa gcaaccatta cgatcaatat cgagtctaat ttaaatgcaa acccgagaat
    13141 aacaatcaag acgcctaaaa ggctaagata attttccata tattttcctc cataaaatga
    13201 caatattttt ttaattataa agcaaaacac ataaaaaata tagttgtttt ctcacgaaat
    13261 agacactatt tttaaatatt tttcgttatt tttttatcac aaaaattatc ttacttattg
    13321 taaggtaaag ctttttttaa tttattgccc gataatatat agaaataagg tctagttact
    13381 gtttttttta aatgattaat aaataacaac ttctttctat gaaattgcaa agcattcatc
    13441 ttcttttccg ctaacgatat atccgtcagt gcttggtaca ctttactaaa aagtatgaga
    13501 ttgccgatat ctggataggt gtgctatact acagaaaaag atatacaatc tgccaccggg
    13561 taggataaag aggatgatca ttccattagg tctttgaagg gatgattttc ctctttttgt
    13621 gtattttttt atagttaagg aggaatgtaa gtatggcatg gatggaatta atcatagcag
    13681 gaattttgga agtattctgg tcaacgatga tgaaatggag tgatggtttt tctaaaatca
    13741 attattcttt ttacacagtg attggcatga ttgctagttt ttactttttg tcaaaggcaa
    13801 tcaaaagttt gccgatgagt ctctcttatc ctatctggac agggattggc gcagttggtt
    13861 cggtcataat tggtgtggtc ttgtttcatg ataagctgaa tctttccact tggttctttg
    13921 tggggatgct actcatcagt atcattggca tcaagattac tagcggccac tagacacttg
    13981 gaataagtac tgatcagaaa aaataagcct ttttatttaa tattcaattt ttttatgaaa
    14041 aaataagaaa taagtccaat gacctagcga cttctccact catcaggtgt atgcttgtac
    14101 tatctataga aaaggagtga atatttttga aaagtctttc ggtccaagaa ttatccaaga
    14161 actttggtca caaacaagcc ctcagcgatg tcagttttag cttatcccct ggcaaaatcg
    14221 ttggattagt aggtcctaat ggcgctggaa aaacaacgat catgaaagct attttaggac
    14281 tgatccatta ctcagatgga acaatctgta ttggtgaaaa tgagatttct ccctctagtc
    14341 ataaagggtt ggaacaagta ggagcattga tcgaataccc gggtatctat ccattcttaa
    14401 caggctatga tcatctgaag ttattctctg aaaccaacga tgtatctgct atcgacacta
    14461 tcgtgaatca gctcaagatg gaaaagtaca ttcacaaaaa agcgaaatcc tactcgttgg
    14521 gaatgaaaca aaaattggga attgctcttg ccttactgaa ccatccgtct atcgttattt
    14581 tagatgagcc gatgaacggt ttggatccac aagcaacaag agatgtgcga aaaatcatta
    14641 ccgacttggc tactcagggc acctctttct tgatctccag tcacttactc agcgagcttg
    14701 aaaaaatggt cgatgagctg atcctgatca atcaaggaaa gatcatcaaa caatgtacaa
    14761 tggctgaatt gaaccaaaca gcgcaagatt tcatcgttat ctctacaaca aatgatctag
    14821 ctgctcgaac gatcttgaca gaagctggat atactttgga agatcctgat aaaatcaagc
    14881 ttttaaaaga aaacgaagaa ttattaggaa ccgtgatcca gctattgtct gcacaaaata
    14941 tccatgtgac agacgtccag catctgacga atgatttgga atcttctcta ttggaaattc
    15001 tggattcagt aaagggggaa gaagaaaaat gacattgctt gtaaaacaag aattatttaa
    15061 attgatcaag aaaaagtcaa ctgctgtttt atctgttcta ttagttgttt tgctcatagg
    15121 aacagcactt ctagccaaaa aatacacgac gatcattgat ccagttgaaa tgactgctca
    15181 gctttttagt gccacatctt ggattgtctt tatcatgatt gcagctgcaa gcacgatcat
    15241 ttcgatggaa gcacaatatg gtacattgaa aaatctcctt tatcgaaagt attctcgagg
    15301 agaaatatta gtaagcaaat ggatcacatt agttatttat tctgtttatt tatacctttt
    15361 agctattatt gtcactgtgt tgatgaaact gattcttttc ccttcgattt ccttcacgga
    15421 gaaggtttct actggtcaaa cactgatcca aagcttgttc acttatactt tgggtagtta
    15481 tatcggttta tggctgattt taagtttagt gttgatgatt gcttgcttta tcaatagttc
    15541 cggcgcatcc atctcagcag gaatcgtctt ttattttgct tcgtcaatca tatctggtat
    15601 ccttattgca ctcatccaaa aatgggagtg gatcaaatgg aatccgatca gtatgttgaa
    15661 tctgcaaaac caaattggaa acgaagagat catgaagcaa ttgactcatc tttctactaa
    15721 tcaaatgcta ttcggtaatt tagcttacat cgttttgttc ttagcattag gatatctcgt
    15781 atttaagcga aaaaatgtat gatgactcat caaaaaagag gctgtgaaag agacgttcag
    15841 ccttattgcc gattggctgt ctcttaaaca ccgtttattc tgaaaaagga gctgtgacaa
    15901 catttgtgtc acagctcctt tcctagtatg tttttgaata aacgacaggc tcacaacctc
    15961 tctttatact tcttttatac ttctatacgt gaagcatccc agtggcaaat aaaaccattg
    16021 caatcactcc gaccatcgtc acacctataa gtaaaatctt atctaagtgg atatgttgta
    16081 caggctcgtt ttgctcctta cgtgctttga ggtaaaaata aatgcctggc aagaaaagaa
    16141 caagaacaag cattacttca ttaaaggcta cgactagcat agcccatact tgaaaggcac
    16201 ttgctaaaag ccctactaaa aattggaccc attctttccg ctgataagaa agtttcattt
    16261 ggtacaatcc taagaaaagc cacgtgaaga aaatagctgc tgtaccaagt gtgtaagcaa
    16321 agttataagc actgtcagtg aataataatg aaagtaaaaa gacattcgta cataacgtcg
    16381 tcaatacgat agcataagtt ggtgccccat ttttgttgag ttttccccat gctttaggca
    16441 aaagtccgtc ttcagccatg tttcccattg tttcaatcgg taagatcgtc catgagagcc
    16501 aaacaccaac taaagaaatg atcaaaccgc cgttgatcac gactgctccc catttaccaa
    16561 ccatcatttc aaacacatag cccatagcag gctgcgcctt gatcgtttgc agctgattca
    16621 tcgtcattgt cccatatgga agcatggaaa ccaagacgta aataataatc aagccgaata
    16681 tccctagaat cgttgctttc ccaacatctg attgtttttt tgctcgtgaa cctacgacag
    16741 aggctccttc aataccaaca aatacccaaa gcatcaccat gatgcaactc aatacttgac
    16801 tggaaaacgg gatcggctgt ccattcgcat tcaatataat gtcgctagaa aagttatcaa
    16861 tgaattgttg gatcgaaaac gtgctgatag ctactacaat aaataaaaat aatggcacta
    16921 atttacagaa tgtgacgata gcattgacga aactagcatt ttcgactccc cgattcacta
    16981 gccatgcata tccccataaa aagactgtac tcatcacgat cgatgccaga ttttgcccac
    17041 cttcaaatac tgggaagaaa tatcctaatg cgctcatcaa caatgttgca aaagctacgt
    17101 tgcctaacca gcatgtgagc cagtaacccc aaccgctgat aaaaccagcg aaacggccaa
    17161 aaccttcttc tgcgtaacta aagatcccgc cttttaaatc tggacgtttt ttattgatat
    17221 tattgatcga caaggagagc atcaacattg ctgttcctac gagtacccaa ctgaaaatag
    17281 ctgggccgcc agccgatccg gagatgtccg tcataatacc aaatacgcca cctccaatcg
    17341 ctgaaccaat tactaaggca gcaagtggaa ttaaaccaat tccttttttc tgttgctctg
    17401 tatccatgta agcatcctcc aaaataaaac cgcttttatc aaaaagtata acaaaccttt
    17461 tttattttta cttaattaat aaaaacttta atagaaatat aattctaccg gcttttttct
    17521 cattatacaa gcaaagcgcc tagtcccttt ccaaattaca ccaccaaaaa acttaaaaaa
    17581 gatgctatac taaaaggaaa gaattggagg atgatccatg aacattttat atatatcgat
    17641 ttcaggaaat acgcgtgcct ttgccaaaca tctagcagaa tatgctgaaa aaatgcatgc
    17701 agaagatcct gtcaatcctg aagttacttt aaaagaaatc catgaaaata gtgattttac
    17761 gaaagaaaca gaaccatttt ttactttcgt tcctacttat ttagacggcg gaaatggttt
    17821 agataacggt gatacagaaa tcttgaccga aacgatgcgt gaatatctgg aacatgaaga
    17881 caatcataaa ctttgtcttg gtgtagtcgg tagcggaaat aaaaacttca ataatcagta
    17941 ttgtctaaca gccaaacaat atgcacaaac atttggcttt cctttcttgg cagattatga
    18001 attacgggga acaccatctg atgtgacacg aatttatcag attttagcag aaaacaataa
    18061 ataataaaaa agaagaagct gaaaaataga tttcagtttc ttctttcgtt tctattgttt
    18121 ctatcatatt aagctttgac atccatcaca ggtgcttttg cttttgcttt acctgttttt
    18181 tccaagacaa agttttttac acgatccata ttggttacca agacgatcat ggatgtttct
    18241 ttgcctgctg ctttgatcgc ttctaagtca gcttctgcta caagcgtatc aggtgtcact
    18301 tgctgccctt ctgttacttt cacatcaaat ggcgtaccgc ctaagtcaac tgtgttgatt
    18361 cccatatgaa gcaagatttc taaaccattt ggcgttgtga tcccaatagc gtgtttcgtt
    18421 gggaagacag agctgactac cccagtaact ggagaataga tatgtccgtt ttctggttct
    18481 acaaagtagc cttcacccat catcttttgt gcaaaaactg gatcacttgc tttatctaaa
    18541 gaaacaactg ttccgtcagc aactgatgag aggatagtca cactttcagc tgaagtttga
    18601 ggtactactt tttcaggcac ttcatttact gtggctgttt cagtcgctaa ttcttctttt
    18661 tctaaacggt ctttaggaat accgaagaag aatgtagcaa cgaagccacc agcataagct
    18721 gccaataatc caaggatgta gcctaaccat ttaccgtcag agatcaatgg gatcaaagcg
    18781 gctcctgaag gtccaatagc gatagccccg acatttccga tcattccgat cactgccccg
    18841 ccgatacctc caccgataca agcagtaata aatgggcgtc ctagaggtaa tgttactccg
    18901 taaatcaatg gttcgccgat tcctaggatc ccgactggta aagctccttt gatcatttct
    18961 gttaattctt tatctttttt gcagcgaatc cataatgcca atgctgcacc cacttgtcct
    19021 gcaccagcca tcgcaagaat tggaagcaat agcgtacgac cagtttcatc aatcatttgc
    19081 acatggattg gagtcaaaat ttgatgcagt ccgaacataa ccatcggcaa gaataatgtg
    19141 cctagaacga agccggcaaa tgctccacca acgccaagta cccagttgat cccaccgacc
    19201 atgccatcag aaatgaaacc tgctaaaggc atgatgaaga aaatttcaat cagaccgatg
    19261 gcaatcaatg aaagagttgg tgtaacgatg atatctaccg catcaggtac tactttatgc
    19321 agttttttct caacgattga caatagccaa acagcgaaga tgacacctag gatcccacct
    19381 tgtccagctg caagagcttc accagtaaat aagtttttca gtggtgcttc cggattcatc
    19441 cctgtcagca tcacaacggc cccgataact ccaccaagag ttggtgttgc accaaaaact
    19501 tgtgcagcat tgatacctgt atagataact aggtagctaa acatcccgtt tttcaagatg
    19561 ttcatcacat cgatatattg ttgccatgtt gctgcatcaa gtgttccggc tgtgactaag
    19621 tttgctaaaa ctgcggcaat ccctgccacg atcccagtac cgacaaatgc aggaatcatt
    19681 ggcacaaaga tattagaaat gtcttttaat accgatttga ttttagatgg tttttgtttc
    19741 gatttttgtg ccgctttcat ttcttgtgcc cgttcgttta cacggtcttt tccagatgct
    19801 gatgaatttg ctgtagctgt acttacagaa gaaagttttt ctcctaattt cacgcctgcc
    19861 aaatcaacca tttgctgtgc tactttgttc actttcccag gtccgatgat gacttgaagc
    19921 tgttcatctt ctactacacc aagcactcct ggaatcgctt ttaattcaga gacatttaca
    19981 agatcatcat tgatgatctt catacgcaca cgagtcatgc agtggacaat gctttctaca
    20041 ttgcccatgc cgcctgcccc tttataaatt tgttttgcca gttcttccaa agtcagttcg
    20101 ttttttgcca tggtcttttc cccctcataa ggtccctttt acaaatccgt ttgcttcagc
    20161 taattttgct tgagcttcct ctttatcact atttgtcaaa atcatgacga tagccagctt
    20221 aacattttga tctgcttctt caaagtactt ttcagctgtt tcgtaatcag cttctgtcgc
    20281 ttgcatgatg attcgttttg agcgttcgat tagtttttca tttgttggtt tgacatcgac
    20341 catcaagtta ttgaatactt tacctatacc aatcatactg atagtagaaa tcatattcaa
    20401 gataagtttt tgtgctgttc ctgacttcaa tcgagtagag cctgtcaaaa attctggacc
    20461 tgcatcgact tcgattggga aatccgcgtg tttactgatt tcggcttgtt tattgcaaga
    20521 aatcgttcct gtgacagcac cgatcgattt tgcgtaatct aatccaccga tcacatatgg
    20581 tgtacgaccg ctagctgcga taccaataac tatatcattt tttgtcaaat tcagcttgat
    20641 tagatcttct tgccctagct cataagaatc ttcggcccct tcgacagcta cagtcattgc
    20701 ttcttctcca ccagcaatta gacctatgac catttccggt tctacaccga atgtcggtac
    20761 gcattcagca gcatctaaca cacctagtct tccacttgtt ccggctccca tataaatcag
    20821 acgtccacct tttttaaagg actcaatcgt gttagcaatc actggttcga tacttgtcag
    20881 ttctttttca accgcagcgg ccactttctg atcttctttg ttcattagtt gaacggcttg
    20941 agaaatactc atctcatcta atccaaaagt ttcttggttt ctgcgttccg ttgttaggtt
    21001 ctctaaattg attttgctca tttttatctt ccttcttttc ttataaattg atagttcata
    21061 ccagctttga tttggttgat caatggtagc tcttctttga taactttagc tactacattc
    21121 actttttcat ccgctggcaa atcatatttg gttaattgga tctcacccat atagcgcaaa
    21181 tacttttcgt tatctaaagt aatagaccct ttcatacgcg tagctgtatt tcttgctggg
    21241 ataggcggaa tctctcgaaa acgtgcatct acgcttcgta tgacatctct tgcatcgtct
    21301 tgccgattcg tatgcttccc taatatatat tcgtaaaatt cttcatctac aggttccgta
    21361 tggagcaaga ctgtctgttc tttttggaaa gaagcaaatt gctcctgaac gttttctgac
    21421 agacctgcat ctccgatgta aacaatatcc gtgttacttg ctaatagatc tagagcgcct
    21481 gcaagaggat ggatccctcg atgttcttcc aaagttggca atccttgata tagtgggcct
    21541 ctcaactctg tatctcctgg tacaaaacct tggacaagga gaccttgaat tttgagccat
    21601 tgattttttt tctgatacca ttctttgtcc agccctgttt cgggacgtgg ataataatta
    21661 tgccaagctt caatctgtga gaaatcagct tctgcttctt tcaattcatc gatatcttta
    21721 ggcgtgatcg tgctagcatt caaactgatt ttcaattgat gtgaccagtc ggcaatctgc
    21781 tgattggaaa tatgataatc cattcttaaa cctgttacac caattgcttt caaaggcgtt
    21841 agatcttcta atgaaaaacc cgctcgttcc aatgcctctc ctgaaatatc gaccatcaat
    21901 tctagtttat tctttttcgc ttcgcttcct agttcgatca atcgcttttg atatgccgaa
    21961 acatcatctt ctggtatatg catggaagtg aaaataccga caaagccatt ggatgccatt
    22021 tggcggatat actgtttctt ctcttctgac aaagaatcgt tcataaatat tgaaaagcca
    22081 aacatattat ccctcttttt ctgtatccgt cttcatttct atgactagag tatatatcta
    22141 aagaaacaaa atttcaatac ttttattaaa ataattaaat ttcatttcta aaggttgagt
    22201 ttatattatc aaaagaattg tcataaccta aaaaaggcac tgctaagcaa aagcagtgcc
    22261 ttgaaatatt ttatttaaat aacacaaaaa cataattact cataagaaac caattctgta
    22321 ttatctacca tgaatgtaaa gaacccctca ttaggcatcg gatgaaaata agcattgatc
    22381 actcttatca aggcattatg gcaaactaac agatagacat tttcttcgtc ttcgatgcat
    22441 tctttcaata aaggaacgat ccgtgcatac acatctaaga ctgactcccc atttgggaat
    22501 cgtacagcga acgctaaacg tgctttttga aagttctcat ctttgcttgg cagtccatca
    22561 taatccccaa aatccatttc taccaatcgt tcatcaacgg tcagcggcaa gctgagacga
    22621 tcagcaactg cttgtgctgt atctcttgct cgttgaagag gggaatggat gattttcgtg
    22681 attggaacag gcaaatctac taccttttct gctagtttct gtgcctgcat ctgtcctttt
    22741 tcagtcagcg gcacatctgc ccgtccgcaa actaatcctt gtgcgttcca agttgtttct
    22801 ccgtgtctcg ttacataaag catgtgattc tctccttcgt tggcaaagtt ccccttaacc
    22861 ataccttgtt gttcttgaga ttacaagggt tagattctct caagagaaat aatctcagta
    22921 gatactttat ccaggaaggt ttgatcatgt tccactagta acatggcagg tttcacgttc
    22981 aagatcagtt gttctaattg ttcttgattg aagacatcca aataattcaa tggttcatcc
    23041 catgtatata gttcagctgg ctgtgataaa gatttagcca attccacttt tttccgttgg
    23101 cccatactca tctgctcgat cttgttatga aaaacatctc tttccatccc aagctttcgg
    23161 aggttgttca aaaatgcttg gtagtctact tggtttttct ctgcaaattc cgccaacgtt
    23221 cctcgattgt cttcataatt ttggcttgca taactaatgc tcagatgttt tggctggtat
    23281 ttttctccta taaccttgcc gttgaatgcc cccagaagat aatggataat ggatgacttt
    23341 cctgcaccgt taggacctga aatcgccacc cgctgatgag gctcgattgt aaaatgaatt
    23401 ggctcgaata acagattttc ataccctaat tgaagatctt ctacgcttaa aagtcgctta
    23461 tggtgagacg cttggctatt catcgtcaaa gaatcgatat attcgatatc ttttaatagt
    23521 ttttctttct cgctgatctg ggtctccatc cgattcacga ttgctttgga tcgtttcatc
    23581 gtccgtgcag catcagcacc cactgctcct ttattcactc gtctagattc agtatcgatg
    23641 aatccgactt gtttctttgt tttatctcct tctcgggaac gagaccattc ggctttttca
    23701 gctgctgttt tctttagcct actgacttct tttttcaatt tttcattttg agccatttca
    23761 aattcatcac gaagtttttt ctgttcttca tagatagaga aattcccttg ataaagttcc
    23821 agttgacttt tttcgattgc taaaacatgg tccactactt catcgataaa tccccggtca
    23881 tggctgacca cgatgaagcc ttgttttttc tttttcaaat aagccgctac ttgttttcta
    23941 ccagagatat ccaaatgatt cgttggttca tcgattaacg ggaaatgagt gtcatccaca
    24001 aataaaagtg ccagtaggac ttttgtcttc tctccccccg atagtgtgct gaattctctc
    24061 cataagattt caggatctgt ttgcatcaat tggagctctc tttcgatttc ccatatctca
    24121 aaatccgtaa tatcatttaa cacgtaatag gttaaacgtt ctttatcttt tgtctgttgc
    24181 gggaaatagg caaattcttg ctgatggatt acttgccctt gataaggtag tttgttttgt
    24241 agaatattca gtaaagttgt ctttcctcga ccgtttcgtc cgataagtcc tagtttccat
    24301 tgtgtgtcaa aatttagatt tgcttgttca aataataatg tgccttggct gtcgtagccg
    24361 aatgtcagat tttttatttc gattttagac attttccatc acctcgtaaa aaaagaccag
    24421 tcctattttc agaactggct aaagaggatg caagggttgg atacacacaa aaagacccat
    24481 acatcgaaaa aaccaagcca atcccgaaaa tctgcacact gcttccttgt ctccacaagg
    24541 tacagtctga atgcagcttt catcaatcga cttaattttt caatgcacgg atccctcact
    24601 ttgtcctata tttgaaatta cgatagcata aagaaaatga ttttgtcaac tacttcggga
    24661 ggatggtgaa aaatctgcta agtgtctgtc ctaagatttt tgttttttct aatgtttgcc
    24721 tgtgttccat tgcttcttct aaacctattg gacccaaatg aatacttaag acaattggga
    24781 gaaaatcaga aagtccttct agctcttggt ctctacttcc gcaaatagcg attattggtt
    24841 ttcgatattt ttttgcaagc actgctacac cgtatggaac ttttccgtgg atcgtttgct
    24901 gatcgatccg cccttctcct gtaatgatga catctgcttg ttcgatcttt ttttccaatc
    24961 cagtgatttg gctgactaaa tcgaaaccag aaaccatctt cgctcccaac aaaaaaaggg
    25021 ctccaccaat accgcctgct gctccacttc ctggaatatc atctaaatcc acctcccaga
    25081 aatcttttat ttgctgagca atctttcctg cttgtttatc taagaaagct agcgtcgtat
    25141 ctattcctcc tttttgtctt ccaaattgcc aagcagctcc ttgttgacct gtatatggat
    25201 tggtaacatc tgcagcgata atcaatttta ctttagaaac aagaacgttt cttcgatcaa
    25261 aatgaagttt tttagtagat aataaaggat ttccttctgt gtacccttct aaagaagcac
    25321 ccaaggattg gagtaatcct agaccaccat cgctacaccc gcttcctcct aaagtgacaa
    25381 taatttgttc tacttcttga agcagtgcat ctttaataag ttctcctaag gcataactgg
    25441 aagcaagtcg gatagtttga tccgttggtt tatcaagtag atctaacccc aatgcttgtg
    25501 cagattcgat gactgcggtg ttttttcctt gccaagttgt caataaatag ctgatttttc
    25561 gctgacggaa taagagatcc atcccatcaa tggtacgcca tgttcccctg agcgcgtaat
    25621 agattgcttc tgcagtattt tctccgccat ctgcaatcgg cacattgatt tttcttcctt
    25681 tacgatcttc ccagccattt agaactgcct gatttagttc aaatgaagaa gcacttcctt
    25741 taaatgaatc aattgccgcc aaaatatcca tctgtatccc tcactttctt cttaagtaag
    25801 acactttttt tcattttttt caaacaaaac aatgctattt tcttccattt ttctatatac
    25861 taaaagggaa ctcattgaat aaaggagaga aaaaacatga aaatcgcaat agctggggcc
    25921 ggagcaatgg gcagccgaat cggattgatg ctacatcaaa gcggaaatga ggtcctcttg
    25981 atcgatcgtt ggcctgctca cattgaagcc attcgtacaa atgggttgat tgctgacttt
    26041 aacggtaaag aagtggtcgc aaaactgcca atctattcac cagaagaaat catcgaaagc
    26101 aacgaacacg tggacttgat cgtagcatta acaaaagcca atcaattaga tgatatgttt
    26161 tgttcgatcc aatccattat tactgacaat acttatgttt tgtgtttact aaatggatta
    26221 ggtcatgaag atgtactgga aaaatatgtg ccaaagaaaa atatcttatt tgggatcacg
    26281 atgtggacag ctggtctagc tggtcccgga aaagtcacat tgttaggtga tggagaaatc
    26341 gaactagaga acttggaacc agaaggcgaa gcatttacaa aaaaagttgt agaagtcttt
    26401 caagaagcaa atttaaatcc gatctatagc cataacgttc gttattccat ttggcgaaaa
    26461 gcttgtgtaa atggaacatt gaatggttta tgcacgattt tggattgtaa tattgctgaa
    26521 ctaggcgcgc aaaaagcggc agagagcatg gttcgaacaa tcgtatctga atttgcttct
    26581 atcgcagcaa aagaaggaat catactagat caagaagaag tgtaccaaca tattgcttct
    26641 acttatgatc ctgacaacat cgggttgcat tacccatcta tgtaccaaga cctgatcaaa
    26701 aaccatcgtt tgactgaaat cgactacatc aatggtgcca tttggcgaaa aggacaaaaa
    26761 tatgatattg ctacaccata ttgtgccttt ttgacccaat tagtccatgc aaaagaagga
    26821 atccttggcg cagaataaaa ggctctctga tgagaatcag ctgaatcagc agctggttct
    26881 ctttttttaa gcccaataaa agatcaaaaa gaaaacacaa ctctcatgat gccataagaa
    26941 ttgtgcttgt ttgtttcagt acataatctc ttcaaaatgt aggtttttta tttgttttca
    27001 acagaggaga ggtcatattc gtattgctca taaatagtgg aatcgttagt gataaatcgt
    27061 tttgcccaat tttctgcatc ataaaattcc aatagctctg ataggattgg cttaaatggt
    27121 gtatgcagaa attccggtaa ttcatctaaa tcacgttctc gaagcaaaaa aatattttca
    27181 ggacgataaa aatgataatg agcaatcgct tgattatccg tcactagttt cttttgaaaa
    27241 tacatggatt caaatgtccg caaagtcact ccttgctgac cctcccgcaa cagttccaga
    27301 atcccgcgcg attcccctgt ttttttcagg tactcttcat aagtaagata tccaggttgt
    27361 tcattccctc gatgtggaag aatgaaatag ttggtcgtaa catctctttt tataaattcc
    27421 tgcttatagc tttctgctcg ttcttttctc ccattattcg ttgcaccaaa aaatagatcc
    27481 gtctttggtt cgctagaaga aaaattcata tgtttcgaat aaaatgaact attatgtttc
    27541 agcccaagtt cttttgcttc caaaaaatca aaatgataaa tctcatcgat tgccggttca
    27601 tcttgtgcct gcttcagcat cgcctcgtgt tctgctttga agtgattcca aaaaaataac
    27661 acaatttttg cattggtaaa tgggcgcacg cgtcgagcca tctccatatc aaatccataa
    27721 tctaaaaaaa cgatcagctg ataatttgcc aactgttgtc tagctgattt aatgaattcc
    27781 gactgtagta aatcttttcc ggaccaaaca tctaaagagc ggatggaagg caaaaaataa
    27841 agtgatttat tttttgcaac tagcagtacg tcatttttgt tcatcttttc cgcctcactt
    27901 tctctgtcac tttttcctat gatagcctgt ttaaatagta aaaagccagt aaaacgtttc
    27961 ctatatttgt atgaaaattt aacatttgta tgaaaatatg atgaaataaa tcattcttct
    28021 attaaaattc gcctaaaagt tttctgaata gttgtaattg tctgaaaatt tgttatcatt
    28081 agtcattgtt aaatattgct atttattctt aatataaatt ttgattgtga atttaaaaga
    28141 aagaggtcat ttatggaaga taaaaaattg aaaaaacaac ttagctccag acatatcacc
    28201 atgttagctt taggtggagc aatcggtgca ggtctattta aaggaagtgg cgaagcgatt
    28261 gggatcgccg gcccttctgt attgattgct tttttgattg gtgggctgat tttatatatc
    28321 gtgatgaaag gtctgggaaa aatcgtttta agcggtggcg acacgcatca cggattatct
    28381 ggtttgatac gcccttatct aggtgctcat tctgctgatt ttactgattg ggtctactgg
    28441 tctatgtgga ttatcaatat catcgctgaa gctgttgcag ctgcttcctt tttgcagttg
    28501 tggttcccgc acattccagc ctgggtattt gtttttatgt tggctgtttt aactacgatc
    28561 atcaatcttt attcggtacg gttattcgca gaaacagaat attggctggc ttttgctaaa
    28621 atcagtgtca ttatcttact gatcattttt gctacttatc ttgtcggtca gcaaatgttg
    28681 ggcacaggcg ttttccctac ccttcagcaa ttgactgacc atggtgggtt tactcctcat
    28741 ggtatgaagg gaatcatcag ttctttgctt gtagttatct attcttacgg cggttctgaa
    28801 ctgattgcta tcacggtaag cgaagcagat gatcctaaac gtgcgattcc taaagcaatc
    28861 aaaggtgtca tgggaagaat catttccttt tacatcattc ctttgttttt gcttttgatt
    28921 ctttttcctt ggaatacttt agcaggcacg aatgtcagtc cttttgtgat ggtatttgaa
    28981 aaaatgaata tcccatttgc agcggatatc gtcaattttg tgattgtcct tgctttgttc
    29041 tcatctatca attcgggtgt gtatgcatct tcaagaattt tgttcttccg tttgaaggat
    29101 cgaaaaggtt cctctagaaa actagctgtt ttaaacaagc atcaagtacc gcaacgtgct
    29161 gttttatttt gtaccagtgt tctttatctt ggtgtagctc tttcttattt tgtcggtgac
    29221 aaattatttg gctatctggc aggttccctt tcgtatacag tattattgat ctggatcatt
    29281 atcagtgcgg catcctttgt actggcacta agaaaaggaa cattatggga taaaggaatc
    29341 agcttttttg cattagctgt cttaggattg attttccttg gtatcctgtt cacgaactcc
    29401 attggggtaa ctgtattgac tggcctgctt tacctgttca tttatttcag ttatcaaaaa
    29461 aagaatgatg cgttcgtatt gacgaatgaa tgaaatcgat agaaaatttt attttattta
    29521 tgtggaatag atggagctat tgaagaaagg agttgtgaca aaagtcttgt tgcaactcct
    29581 ttttccgaat aaacagtctc atgacctctt ggtaaacggt gttcaaaaac cctctgtgca
    29641 aaataattga ttgttctcca tgctcatgac atgatagaag aaaggaatga aaaaaaggag
    29701 tttgttttaa atgaaaaagt attggaagtt tttgttgatg atcggtgttt caacggtagt
    29761 tatgtttggt atgatgtact tgaatgtcta tgcgctcgat catatcttct tcagtcgtac
    29821 acgagtattc atggcgttga tgatgggtgc agtcatggca gtcatcatgc tgttgttcat
    29881 gtggaaaatg tatgaaaaca aaaagataaa tgttatgatc ttagccgcta gtcttcttgt
    29941 ttttgccggt tccttgttta tggtacgaag ccaaactact gtcaacgaca cagcttggat
    30001 gaaggccatg attcctcatc attctatcgc tatcctggca agtaaacgag ctgatttaaa
    30061 agatcctgaa gtaaaaaaat tagcggaaga aatcattcag gcacaagaag aagagatcga
    30121 caaaatgaaa aaaatgatca aagaaatgga atgaccatta tccgtccaaa taaaaaaaga
    30181 ggatgttcca gaagttatca gcttcaagaa ataagaagaa gctacttctg gaacgccgtg
    30241 aataaggggt tgtgaaaaag ctgccctgca tcaagtaata agaacagcca aacaaaaata
    30301 gcttctccta tttttcgttt ggttaggctt attaccgcag atgcaagctt ttgaacaccg
    30361 tttattaaga ggttgtaaaa tcagcgttct gacctgagta ttagagagac aaatggaaaa
    30421 atagttcctc atattttgcc attttttgag ctaataccga gggtcagctg attgaacacc
    30481 gtttatcgag aggttgtgaa aaagtcgctt agtttcgcgt attaagaaaa attttgtgaa
    30541 atggctttcc acatttttgt ataaatttgg cttaataccg agaaactggc ttttgaatac
    30601 cgtttattcg taaaagggat tgtgacaaaa gtcttgtcac aatccctttt tatgttttta
    30661 ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt tttttgagat
    30721 tccccaacct gtgaaggcac tgaccatcga aaacacagga gaaagcaaac tgaaaaatac
    30781 gaatggcaag taagtgagtg taggaatacc aaatgtactt gctacgaaac ttccggcaat
    30841 tccccaaggc actaagtagt tgattactgt tccaccatct tctagcgttc tacctaatac
    30901 agttggatca aatcctgctt tttcataagt ttctttaaat gcattaccag gcagaataac
    30961 agataggaat tgttcaccaa taaaaatatt tactccgata cttgtcatca atgttgtaaa
    31021 aatcaaattt ggtgtgttcg tcatctttct tgatactcgt tccatcacgg ttgagatcaa
    31081 gccaaattcg atcaacaatc cacctaatga caaagttaga ataatcaatg acacagtagg
    31141 catcatactt tcgattcctc cgcggctaag cagtgaatcg atttgttggt ttccagtatt
    31201 tgaaacaaac cctgattcga tgaccccagc caacttcgtt aaggaagttt gtgggttttg
    31261 aataaaaatc attcctactg ctacagcgat attcaacaaa atcgttaaaa ttgccggcac
    31321 ctttttccat gcacacagta acattaaaaa taaaggaatc agtgaccaga ttgaaatagt
    31381 aaagtttgct tctagaacat cagtcacttc acgaatagat gaaagacttg cggctttact
    31441 tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggga cagttgacca
    31501 catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg ctagatttgt
    31561 tgattcggat aatggagaca tcttatctcc aaaaacggca cctgaaacaa tagctccaac
    31621 aaccagcgct ggatttaagc ctagtgttgt cccaataccg aaaaatgcaa tcccaatcgt
    31681 tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaca caacaaatac
    31741 agaagggaca aaccactgga cactgatcaa tttgaaccca atgaccatta gagttggaat
    31801 gatccctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa taaagattgg
    31861 gatgattcct ggtttgatgc cattgatgat tccttcgtgc agccaatctg tcgggtatct
    31921 ttttatcact gcatacaaca tgaccattcc gatcgctgct aagatcgtga tattaggtga
    31981 gacctttaat ccgacaacgc caatcgcaat gcctaaaaca ataaccatta atacaagtgt
    32041 tgcttctaaa aaacttggtg ttcctttttt tcccatgata atctctcctt ttttagttgt
    32101 tcttatgttc taaaaaagtt aagatatcgg attactccgc cgcaattcat ccgcgattcc
    32161 tcctttataa aaataaaaag acctgtttta aactaaggac gaatgactcc gcggtaccac
    32221 cttaattaaa aacagatctg tttttcactt tcaaactttt attcaaatgt atggactttc
    32281 catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt ctgaacaaaa
    32341 cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag tttaccttcc ataagatcat
    32401 ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta taactttcac
    32461 acacaagatt attttttact agaaagtagc gccctcttgt ttttttcttg ctactatttc
    32521 ttgatgttct tgcttgattc tttctaatag ctttggctct ttcaacagat caagagctgt
    32581 attggcgagt agttctgctg caatcgcaat agaagcaagg cctttgtcac ttttagcagc
    32641 agctttgaat tcttctgtgt gtccggcaat atatgtctca gagattgcta ccgtaggctg
    32701 gattgttggt atgacttggc tgacatttcc tacatcagaa gaaccgagac ttgttctttg
    32761 ttccgtttct atttcttcat ctggaacacc tgcttctttt gcatgctgga agaataagtc
    32821 atcaaaagaa ggagtaacga tgacatcatc aactgcattt tggaacaatc caaactcaaa
    32881 agtcgtgccc gtacttatcg cagcacctcg tacgatattt tccacttttt catatacttt
    32941 atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt ccagcagcgt aatctggaat
    33001 gacgttggca gctactcctc cgtctgtaat gatcccatgg atattgacat cttttggcaa
    33061 ttgcaagcgt agagcgttga ttccattaaa cacttggatc aatgcttcca aagcatttac
    33121 tcctttttca ggtgctgctg ctgcatggga agcgacaccg taaaatttga tgtcgactgg
    33181 atcattcgct aaagattctg tcgttttccc ataacgaaaa gctggatgga cgcataacgc
    33241 tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg cctttagctg atccgttctc
    33301 gcccccttct tcccctgggg tgccatatac acggatttct ccaccagttt catcaatgaa
    33361 ttgcttcact atgctggcgg ctaatacgga gtaagtacca aacaaattat gcccgcatgc
    33421 atgaccaata cctggtaaag catcgaattc tgccaaaaag gcaattgtgg gaccgggttt
    33481 attggaaata taacgtgcat caaaggctgt tcggtgtcca gctacttctt tttctaccca
    33541 aaacctttct ttttctaatt gtttaatcaa cgctgctgag gaataaaact catagttact
    33601 tacttcagga tgttcgtgga tatctagagc aagtgcttga tattctggta aacgatattg
    33661 gattagatcc ttcaattggt ttgttgagat tgttgttgtc ataaaaaatt cctcctatgc
    33721 tagtcatttt tcttattttc tcccgaatgt ttcccatgca ggcacgcttg atccttttga
    33781 tgttttctcg attactttga ctgtgtcttc tgtttgataa gcgtctacta ttttttgata
    33841 cgttttattg ttttcatctt cttttcttgc aacgatgata ttcacataag gacgtgcatg
    33901 gtcatccact ggttctaaga agatggcatc agaagcagga ttaaatccag catctacagc
    33961 tacaccgcta ttgatcactg aaatgtctac atctgacaaa gcacgtgctg tttgggaagc
    34021 atctaattca gaaatgtcta gattttttct attctcggta atatcagaaa cagtgggcgc
    34081 ttgtcctttt gccttatcca ctttgatcaa tccagcagtt tgcaataaca gaagagctct
    34141 gccgccattt gtaacatcat tagggattgc tacttttgct ccgtctttga tatcagctac
    34201 atccttcaaa gtgttagaat aaattcccag cggtgcattg acagtatttc cgatcgatac
    34261 taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag aattgatgtt ggaaagaatt
    34321 caaatcaatc gatccatctg ctaaagccac atttggttga ttgtaatctg taaatttcac
    34381 gtattccaaa ttaatgttct cctttttcaa acggtctttc acgttgtccc atacatctgt
    34441 atcttctcca ataatcccta gttttacgat agtttctttt ttgtcagttg tatctgcttt
    34501 tccttggcta caccctgcca accaaataat tgctacaaat gtaatgacta caaaacgaat
    34561 aatttttttc attttttctc ctccactttc aatgtgtaat ttttttaatc agttgattac
    34621 tgataaattg acttaaaaaa actaagatta gaatcaataa tgtagccaca atcgttacat
    34681 ctgtttggaa tcgattatac cctctcgata tagcaagatt ccctaatccg cctgcaccta
    34741 ctgctccagc catggtagtc agtccgatca cgttgatgat agtcaacgcc gagacccgaa
    34801 tgataccagg caaaccttct aacaaataca cacgtaaaat gataccgatt ggactggttc
    34861 ccatcgcttc tgccgcttcg atcaccccag gatcaacttc tagcagtgcg ttctcgattt
    34921 gacgagcaaa aaacggaaca actccaaaaa tcaatggcac taaagctgct ttcgcaccaa
    34981 tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag agaaagcaag ataatgaaag
    35041 ggatggaacg aatgatattg atcagcttat caagtatttc aaatagcaga cggttagcta
    35101 gtaatccatt agggcgtgtc actactaacg tcacacctaa gatgattcca atcatcccgc
    35161 caatgaatgc tgtccaaaaa gacatatata gtgtttgctt cgtcgcttcg acaaattcat
    35221 ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa atcagtcatt ttatcttcct
    35281 ccttcgatca ctttgatacg actatctaaa tcgttttttt gtaaaatatt tatttttaca
    35341 ccagatttga tcaaataatc caatgctttt ttccgctgtt tggtttctcc agctaaagta
    35401 acgatcaaac tccctaacgg cgtttcttgt aataactcta cattgccata taaaatattc
    35461 gctgttactt gatatttgct gtacagatga gcgattagag gttcgttcgt ctgatttcca
    35521 atataactta attccactag ccatttattg gcgatctgat cggcaaaagc agaatgggca
    35581 atgatcgttt ctaatgcttg gtcaagatga gtagctgttc gaataaaatc tttggtcaat
    35641 tcttcttcag gattgctgaa gatctggatg ctgctacctt tttcaacgat tcttccatct
    35701 tccataaccg ctaccttgtt gcagatttct ttgacaactt gcatctcatg agtgatcagg
    35761 acgattgtta aacctaactg gcgattcaat ttttttaaca atgcaaggat ctgaagggtc
    35821 gttttcggat caagtgcact ggttgcttca tcacataata ataccttagg ttcattcgcc
    35881 aaagctcgtg cgattgctac tcgttgtttt tgtccccccg acagttgttt aggataagca
    35941 gatgcttttt cttccaaacc gacaagttcc agtagttcat tcactttttg acgacgttcc
    36001 tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt tgtcaaaaat agttcggctt
    36061 tccattagat tgaaatgctg aaagatcata ccgatggcct ttctttcttt tcgcaattct
    36121 ttgggagaga gctgactcag attcgtctga ttgacaatga cttctcctgc tgttggtttc
    36181 tgcagcaaat tcatcacacg aactaacgta cttttccctg cacctgagta accgacgatt
    36241 ccataaacat cgcctttttc aatcgttaaa tctacagaat ctactgcctg tatctctttt
    36301 tctttttgtt tgaaacatac agaaacatct cgcaattcaa tcattaaaat tcctccttat
    36361 ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc ttgaggacgc ttttttgcgt
    36421 gttaccacct catgttcaag ctgtgttcac acacaactcc tcttcaagta cgatcatact
    36481 ctagcaagat atcggtcgca gccgtcatcg ccttacatct atgctcggga tgaattgctc
    36541 gatggccatt ttccaatagt cgttccttgc ttcttctcag ctaccgaagc tctctgtcaa
    36601 aggttcttct atcgtactta ccatttcaat gcaaataata ttcaaaaaaa aagtcctttt
    36661 actaacataa actatgtcag taaaaggacg acgtatcgcg gtaccacctt ttttcggaag
    36721 tttccttccc tcaagcccaa catctcaaaa agagagattg gcgttcgttt taacggtcga
    36781 acagttccga atttgcctac ttatcgacaa attattctcc aaggccattt tcagcttttc
    36841 ttacttgact cttctcacca gccagagcct ctctgcaaag tttccaaact tactttcctt
    36901 ttcaacgaaa tcgatatttt gttgttggga ttaatctaca tgaggaaaac tgaaaagtca
    36961 agtacgaaat tcaaattatt ttttctatat ttatttttct gtttttttat ttaacatttc
    37021 aataacagtt cgaagatctt ttccttccgc aagaagtttc aatttttcct tttcttcgac
    37081 ggtataattt cggacaaaac tggaatcagg tatcaaaaca acgcctaatc ctgctcgtga
    37141 agcagctgtt gctcctacta aagaatcttc cactgcaaag gctgaactag cttctaatcc
    37201 tgttcgttcc aaagctgtca gataaggaat cggtgaaggc ttgttctccg acacttcgtc
    37261 tccgaatgta aacgtgtcca agtaatcagc taatttaaag tgatccaaga tatctgttgc
    37321 tcttttcgta acagtggtcg tagcaatgcc tagtttcata tgacgttctt ttaagtctgc
    37381 caatatttct tttgcatatg gttttaagtg gatggctccg cttgtcagct gttgataaaa
    37441 atattcttca cgcttcgctc ggacttcctg tactttttca gggctacctg ctgctttcac
    37501 taaaatatca aaactttgtt tccagttttt tccgccccaa gcgtcaacga tttcttttgg
    37561 gatatggata tcaaattgct gaaatcccca aagccagcca tcacgatacg ttttttctgt
    37621 gtcaactaac aaaccatcta aatcaaatat tgcacctttc atctatacat taatcctttc
    37681 caaaacaata cacatagttt agcacgactg gtccaaaaag aacagaagca aagaaccagc
    37741 cttctcgttt ataagagttc ttggaatcga cggatataga ttttcttcac agctgtcaca
    37801 agcgccagat aagcgatgac tgtagcaaat aaccataacc agtaattgcc aggaagtggc
    37861 atcaagccta attcagcacc aaaacttgta aaaggaagga cagaaccgac aataattcct
    37921 aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt ggataaatgg tactttcggt
    37981 gtacgcagtg catggagcac taaggtttgt gtccatagtg attcgacaaa ccatcctgca
    38041 tggaataatg cgatgaaaat cactcgctgt gaactatcca atgtatggaa acttccgccc
    38101 actacagcag gacaaataac aaaatacatc aacaagtaag tagtaatatc aaatatcgaa
    38161 cttgttggac caaagtaaac catgaattcc ccaatactag atgcattcca tttttttggc
    38221 tcgtccaaat attctttatc catccgatcc catggcaagg aaatgcagga aacatcatag
    38281 atcagattca aaaacaaaag ttgtaaaggc agcattggta aaaatggcag gaacgtactt
    38341 gcaatcagca cggaaaacat attgccaaaa ttagaacttg ctgtagcctt gatatatttc
    38401 atgatattcc caaaagtttc tcgtccagaa agaaggcctc tttccaaaat cgtcaaatct
    38461 ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat ccacagctgt atctacagaa
    38521 ataccgatat cagccacttt cattgcagga gcgtcattga taccatctcc taaaaatccg
    38581 acagtatgac catttttacg taaagctgtc gtcaaacgtg ctttttgctg aggattcaat
    38641 tttacgaata cttcatggtc ttcagctact tgtgctaatt catgatcact catttccgag
    38701 attttctcac cggtaaccaa ttcattgatc tctagaccta cttgacggca cactgaacgt
    38761 gtaactaatt cgttgtcccc agtcagaact tttacagcta caccatgttc tttcagagct
    38821 ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga aagcaagata accaatcaaa
    38881 accatgtctg actcatcttt gactgaaaat tctccaacga cgcttggatt ggtcttttgt
    38941 gcgacaccaa tcactcgtaa gccatcttca ttaagtgact gtacttttgc aagtacggct
    39001 tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa gatcaataaa tttagaaatg
    39061 ttcagcattt cttcaatcgc accttttgtg atcatttgtg ttttaccagc tggatcagca
    39121 accacaacac tcatacgacg acgttcaaaa tcaaaaggaa tttcatccac tttttgataa
    39181 ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa tgatagccac atctaacaaa
    39241 tttttcagcc ctgtttgata gtagctattt agatacgcat ggcgcaaaac acgatcatct
    39301 tcatttcctt cacaatccat atgatattca agaatgattt tatcttgtgt caatgtcccc
    39361 gttttatccg tacataacac atcgattgca ccaaagttct ggatggcatt caaatttttg
    39421 atcactgttc cttttttggc catcacactt gctcctttga ccaaattcgt cgtaacgatc
    39481 attggaagca tttcaggtgt tagaccaact gctacagata gtccaaaaag aaaagcttct
    39541 agccaatccc cttttgtaag cccattgatg acgataactg ctggagccat caatgacata
    39601 aatttgatca gtagcatgga tgttttatgg atgcctaatt caaagcttga ttgaattggt
    39661 ttttcagata gcgtttctgc tacatgacca aatagtgttt catttccaac agaaacaatg
    39721 attccttccg cacttccact gatgacatta cttcccataa agacaagatt ttcgtaactt
    39781 gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct tttctactgg atagctttcc
    39841 cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg acaataaacg catatccgct
    39901 ggtatcatat cccctgctga aagccgaaca agatctccac agacgatttc ttccatagga
    39961 atctctgtgt actttccatt acgttttaca gctgccgtta ctttcacaag tgatttcagt
    40021 ttttcagccg cttgattgga acgtacggac tgaatcaacg tcattgtccc gctgacgata
    40081 accatagtga agataatggc tacaccgaaa agatctttat ctccaggagc tgctaataca
    40141 tattccgtga tgaatgaaat aattcctaat gcgatcaaca ctaatgtaaa tggcgtgatg
    40201 tatgctttca atatttctac aatgaatggt gtttttttgc catatgaaat cgcattttca
    40261 ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca atccatttgc tgatgcatgg
    40321 aatagttcaa ataattcttg tttcgttttt ccagcaaaag ctgcatagat tttttgtgta
    40381 tctttctttt tttccatctc aatctctcct ttgtgtccaa aagacagctg ttctcgctgc
    40441 ttttggtctt tagctattca tcggatcgat agagaaaaaa ctgaaagggg ctgagaacag
    40501 atagataata gccctggcct ttcctctaga tccttgtttt tcgaatgact gtcatccatt
    40561 tgttctcatc tcctttacta agtaatttta attcatgact tccaatcatt tttcgaatag
    40621 ttatttttcc aattagacca cctccttttt atttttcacc gatggggatt tgcggcaaca
    40681 aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa agcatattaa aaaaagcttc
    40741 tcagatctca tcgttgagtt ttgacactgt acaacgtaaa aagcagatac ctgcttttag
    40801 ctaccttatg aaaagcctta tctcgacaat tcctgttcta cccattggcg tctctcgacg
    40861 tttttgggca gtagcctatg tttgtatagg agcctcacct aacaaatctt attcggtttt
    40921 ccttcgttaa tataacaact aaaaaagagg atgtcaaatc aattttccat gtttttcata
    40981 ctttttttaa aatacacacg ttatattcct gtctcacgcg gttttatttg tctcattttc
    41041 cacctcccgc tataatagaa atatagtagg aaacgaggtg ctgttatgga aagaacactt
    41101 gttattatca agccagacgg cgtgagacgc catttagtcg gaagcatcat ccaacgtttt
    41161 gaagcaaagg gactggccat tgctgaaatg aagtttgaaa ctatgactcc tgaattagca
    41221 aaagaacatt atcagcactt gactgagcgc agtttttttg atgaactgat cgattacatg
    41281 acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg aagtgatcga tatcgtccgt
    41341 aagatggttg gagcaacaaa agctgccgat gctgttccag gtacgatccg aggagactac
    41401 gcgctgccgg ggactgaaaa catcattcac gcttctgatt cccgtgatgc tgcggtaaaa
    41461 gagatcgccc gctttttccc gccattcgat ataaacaaac cgtctgaaaa agcggcgaag
    41521 tgatacaaat tctaaactgc tggtctagtt gctgggttca gcaatggcca gcagtttttt
    41581 ctctaaggac ctccgttgat tctttcctaa catatattcg agcactgtga agaattcttg
    41641 gtagtctttc gtcttttctt cccctaaagc agcagaaatc aatctttgat aataatctgc
    41701 catcaatgtt tcatagatca ctgtacttct ttctttatgt gctaagctcc gtttcatatc
    41761 ttcattcaca ctacgtgcct ttttcaaccg accattttct atataaaacg aagtcaggtt
    41821 cattaaaaaa gtaaagagat actgctcatg attgttcaac tgtgctaatc gtcgcattct
    41881 ttttttgatt ttcaaataat tgttctcaat gaaccgatca ctgaatatcc aaggaaaatc
    41941 agctagaata gatagttcaa attgaccata gtctggtatc tgcatcaagt attcttcaat
    42001 gattcggcat tcataacgta aaaattcaaa ttctgtctca gatacttctg ttttttcgac
    42061 catgtgaaga ttcaaaacca aataatacag atcttctgtt ttcttaaaat gcctacggtt
    42121 attgctgatc tctttataag gatcaaagct gtcttcttgt acccgatcta gcattcgtct
    42181 ttttttcttt aactttattg gttcatccag ctggtttcgc atccattcat attctgcaag
    42241 tgtcatgttc attcgctcta aaaatgatct caatgttaca aatgacattt ttttcactga
    42301 atttgtctca atcccgacta gagaagtctt aaaacagatt ccttccgcta attgggactg
    42361 tgtcaacttc ttgttgactc gaagtttctt gatcaattca ccatcataca taatagttct
    42421 cctttttaat ttaaattttt ccacattcaa taaatagata cgttaaaaag gaaaaataca
    42481 cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca accttcaagc attagaatgt
    42541 tgtctaacta ctgaaggttg gtttgattgt ttattgatta tttttttgct gttcaacgtc
    42601 tgttcttgtt actggatata agttggttgt tgttttatta ccattttttg aaaagacact
    42661 tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta cgttccgctt catttttata
    42721 gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc acataaaacc gcaagagatt
    42781 ttcctgattc agcttatctg aaagacttaa cgcagtcttg actttttcct gatctttgga
    42841 gatttcctca tcgattcctg ctgctttcgt atcgatgatt tctcctgtct gattattgta
    42901 agcttttcct cctaggacgg tgtatttggg tgtcacaaag ttcccatttc gaaaagcaac
    42961 tacttgatca tgctgagaag ataataagtc tgtaccaaaa tgaagataat ctttatcatc
    43021 gattcccaat agatgtagta atgtcggcaa aacatcgatt tctccaccgt attcatgatt
    43081 gactgtccct ttagtataac caggcatatg gatcatcaat ggcactcgtt gcatctgtgc
    43141 gttgtcaaat tcatcccatg tatctggatc tttaccaaga gcgcttgcta aatctttatt
    43201 atctgtattc gagatcccaa aatgatcccc gtaaatcaca aagattgaat tttggtaaat
    43261 accagatttt ttcaaatacg taaaaaattg ttccaatgat tgatccagat aatgtgccgt
    43321 tcgaacataa ttatctactg tgctattgcc agtattcaaa gatggaaagt cgaaattctt
    43381 gtcatccgta taataaggcg tgtggttggt tacggaaaga aatttcgtgt aaaacggctg
    43441 ttgtagatgc tcaagatatt gggcagattc tctgaataaa tctttatcta atatcccata
    43501 acctaacgtt tcgtcggatt catcaaaata agatcgatca aagaaattgt cataacctaa
    43561 gtttttatat acatgatctc tattccaaaa actagctaca ttcccatgga aaacagcgct
    43621 tgtatagcct tgcttttgtc caaggatcgc tggtgcggct tgaaagacat tgtctgaccc
    43681 aagttctgtg aataatgagc cttgaggtaa accaaatgtg ccagtttcca acatattttc
    43741 agcatcactt gtctttccct gtcctacttc atgaaagaaa ttgtcaaagc tgatcgttgc
    43801 ttgattctgg aaaatactat ttaaaaacgg tgtgacttct tgtccgtcta ccttcatatt
    43861 aatcaaaaac tgctggaaac tttctaaatg gagaacgatc acatttttcc ctttagcgat
    43921 cccaaatgtt tcgggatttg gctctgcata atgtttcttt gtataatcta aaacttcatc
    43981 aatcccatta ctgcttgcat gcgcgcgaac actgctagtc attcctgttt tgattccgtc
    44041 ataaatagta tacgcatcga ttcctagata tttgacaata tatgaacggt caaatgttcg
    44101 ctgcagcaat tgtggacggt tggcttcgct cagcgctaga tttcctgaaa aaataagccc
    44161 tgaaagacag gtaacagcga tagccatcgg tttgccgaca gggttgcttt tgataggtat
    44221 tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca gccagtagat
    44281 gacatcatgg ggcttcatca aagaaaagga gcttcctgac aatccttgcg acactttcga
    44341 aaagcctaat acagatttga ctgtaatgaa atctgtgaat tcccgataaa aaataatatt
    44401 caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa agaatagcta acgctggctt
    44461 tggcttttta atatacaaag aaaggccaaa aaacaataag gtagtcgcaa ttgggttgat
    44521 ccacaagata aagtactgga tcgtaccttc cacacctaat gaaaaatctg catagtaggc
    44581 aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa acgattgcta aacgattttg
    44641 gcacaatttt ttaagttgtg tcacgtatat cacttctctc tattcacatt ttttcttatt
    44701 ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat cttaagattt ttttattctt
    44761 tctaaagatt attccgtcca cttttcacag cataaaaccg ctgcgatgta agcgattaaa
    44821 ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc cacggtattc aaaagccagt
    44881 ttctcggtat tcgtacaaaa aaagaggctg tgacaaaatt cttgtcgcag ctccttattt
    44941 cttgatgcag gacagctttt tcacaacttc ttccttaaac ggtgttctcc tgccaactcc
    45001 tcggccacaa gtcacaatat ttataaaaca tgagaagctg ttttttgaaa ttgttccttg
    45061 tggctcagag ttaaacggca ggctcaagac ctcttgatac acggtgttca atcagctgac
    45121 cctcggtatt agattatgtc aggacgctaa ttttacaacc tcttggtaaa cggtgttcaa
    45181 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tataaggagc tattttttga
    45241 aattgctcct tgtggctcag agttaaacgg caggctcaag acctcttgat a
//
LOCUS       DAIGWC010000014        45140 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.014, whole genome shotgun sequence.
ACCESSION   DAIGWC010000014 DAIGWC010000000
VERSION     DAIGWC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.014"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            212..604
                     /locus_tag="NOB74_000803"
     CDS             212..604
                     /locus_tag="NOB74_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI1220009.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="NOB74_000804"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="NOB74_000804"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HCI1220010.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="NOB74_000805"
     CDS             3165..4775
                     /locus_tag="NOB74_000805"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HCI1220011.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="NOB74_000806"
     CDS             5067..5936
                     /locus_tag="NOB74_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HCI1220012.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="NOB74_000807"
     CDS             6101..7372
                     /locus_tag="NOB74_000807"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCI1220013.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="NOB74_000808"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="NOB74_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HCI1220014.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="NOB74_000809"
     CDS             8763..9026
                     /locus_tag="NOB74_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HCI1220015.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="NOB74_000810"
     CDS             9471..9920
                     /locus_tag="NOB74_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1220016.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="NOB74_000811"
     CDS             9977..11395
                     /locus_tag="NOB74_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1220017.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="NOB74_000812"
     CDS             11395..12255
                     /locus_tag="NOB74_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HCI1220018.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="NOB74_000813"
     CDS             12429..13202
                     /locus_tag="NOB74_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI1220019.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="NOB74_000814"
     CDS             13349..13714
                     /locus_tag="NOB74_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HCI1220020.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="NOB74_000815"
     CDS             complement(13862..15070)
                     /locus_tag="NOB74_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1220021.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="NOB74_000816"
     CDS             complement(15089..15367)
                     /locus_tag="NOB74_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220022.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="NOB74_000817"
     CDS             15521..16216
                     /locus_tag="NOB74_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI1220023.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="NOB74_000818"
     CDS             complement(16658..17455)
                     /locus_tag="NOB74_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HCI1220024.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="NOB74_000819"
     CDS             complement(17452..18636)
                     /locus_tag="NOB74_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCI1220025.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="NOB74_000820"
     CDS             complement(18661..19908)
                     /locus_tag="NOB74_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCI1220026.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="NOB74_000821"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="NOB74_000821"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HCI1220027.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="NOB74_000822"
     CDS             21888..22202
                     /locus_tag="NOB74_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HCI1220028.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="NOB74_000823"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="NOB74_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HCI1220029.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="NOB74_000824"
     CDS             22887..23531
                     /locus_tag="NOB74_000824"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HCI1220030.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="NOB74_000825"
     CDS             23546..23875
                     /locus_tag="NOB74_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HCI1220031.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="NOB74_000826"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="NOB74_000826"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HCI1220032.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="NOB74_000827"
     CDS             24863..25687
                     /locus_tag="NOB74_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HCI1220033.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="NOB74_000828"
     CDS             25680..26027
                     /locus_tag="NOB74_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HCI1220034.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="NOB74_000829"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="NOB74_000829"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HCI1220035.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="NOB74_000830"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="NOB74_000830"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HCI1220036.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="NOB74_000831"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="NOB74_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HCI1220037.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="NOB74_000832"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="NOB74_000832"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HCI1220038.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="NOB74_000833"
     CDS             31657..32451
                     /locus_tag="NOB74_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220039.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="NOB74_000834"
     CDS             32441..34483
                     /locus_tag="NOB74_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220040.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="NOB74_000835"
     CDS             34764..34913
                     /locus_tag="NOB74_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HCI1220041.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="NOB74_000836"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="NOB74_000836"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HCI1220042.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="NOB74_000837"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="NOB74_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HCI1220043.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="NOB74_000838"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="NOB74_000838"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HCI1220044.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="NOB74_000839"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="NOB74_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HCI1220045.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="NOB74_000840"
     CDS             39330..40412
                     /locus_tag="NOB74_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HCI1220046.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="NOB74_000841"
     CDS             40412..41215
                     /locus_tag="NOB74_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCI1220047.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="NOB74_000842"
     CDS             41285..42025
                     /locus_tag="NOB74_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI1220048.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="NOB74_000843"
     CDS             42036..43040
                     /locus_tag="NOB74_000843"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HCI1220049.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="NOB74_000844"
     CDS             complement(43085..44929)
                     /locus_tag="NOB74_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220050.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14545 a         7848 c         9380 g        13367 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaatttat cgttattata tgattaagaa ggattgaata
    45121 aagaaagaag ttgaaaacga
//
LOCUS       DAIGWC010000015        44484 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.015, whole genome shotgun sequence.
ACCESSION   DAIGWC010000015 DAIGWC010000000
VERSION     DAIGWC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.015"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..1152
                     /locus_tag="NOB74_000845"
     CDS             <1..1152
                     /locus_tag="NOB74_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HCI1220051.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="NOB74_000846"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="NOB74_000846"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HCI1220052.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="NOB74_000847"
     CDS             2728..3003
                     /locus_tag="NOB74_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HCI1220053.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="NOB74_000848"
     CDS             3009..3776
                     /locus_tag="NOB74_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HCI1220054.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="NOB74_000849"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="NOB74_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HCI1220055.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="NOB74_000850"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="NOB74_000850"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HCI1220056.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="NOB74_000851"
     CDS             7920..8222
                     /locus_tag="NOB74_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HCI1220057.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="NOB74_000852"
     CDS             8225..9388
                     /locus_tag="NOB74_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCI1220058.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="NOB74_000853"
     CDS             9414..12842
                     /locus_tag="NOB74_000853"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HCI1220059.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="NOB74_000854"
     CDS             12863..13987
                     /locus_tag="NOB74_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220060.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="NOB74_000855"
     CDS             13977..14414
                     /locus_tag="NOB74_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI1220061.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="NOB74_000856"
     CDS             14398..14736
                     /locus_tag="NOB74_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HCI1220062.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="NOB74_000857"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="NOB74_000857"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HCI1220063.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="NOB74_000858"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="NOB74_000858"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HCI1220064.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="NOB74_000859"
     CDS             15893..16936
                     /locus_tag="NOB74_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HCI1220065.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="NOB74_000860"
     CDS             17095..17823
                     /locus_tag="NOB74_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HCI1220066.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="NOB74_000861"
     CDS             17939..18184
                     /locus_tag="NOB74_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI1220067.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="NOB74_000862"
     CDS             18181..18399
                     /locus_tag="NOB74_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HCI1220068.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="NOB74_000863"
     CDS             18535..19074
                     /locus_tag="NOB74_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HCI1220069.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="NOB74_000864"
     CDS             19067..21340
                     /locus_tag="NOB74_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HCI1220070.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="NOB74_000865"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="NOB74_000865"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HCI1220071.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="NOB74_000866"
     CDS             complement(22513..22767)
                     /locus_tag="NOB74_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HCI1220072.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="NOB74_000867"
     CDS             complement(23167..23436)
                     /locus_tag="NOB74_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220073.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="NOB74_000868"
     CDS             complement(23906..24361)
                     /locus_tag="NOB74_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HCI1220074.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="NOB74_000869"
     CDS             complement(24499..26427)
                     /locus_tag="NOB74_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI1220075.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="NOB74_000870"
     CDS             complement(26624..27457)
                     /locus_tag="NOB74_000870"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCI1220076.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="NOB74_000871"
     CDS             complement(27649..28353)
                     /locus_tag="NOB74_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI1220077.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="NOB74_000872"
     CDS             complement(28376..29002)
                     /locus_tag="NOB74_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI1220078.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31703
                     /locus_tag="NOB74_000873"
     CDS             29328..31703
                     /locus_tag="NOB74_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HCI1220079.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31727..32218)
                     /locus_tag="NOB74_000874"
     CDS             complement(31727..32218)
                     /locus_tag="NOB74_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HCI1220080.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32405..33325
                     /locus_tag="NOB74_000875"
     CDS             32405..33325
                     /locus_tag="NOB74_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1220081.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33479..33823
                     /locus_tag="NOB74_000876"
     CDS             33479..33823
                     /locus_tag="NOB74_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HCI1220082.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34013..34513)
                     /locus_tag="NOB74_000877"
     CDS             complement(34013..34513)
                     /locus_tag="NOB74_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1220083.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35041..35124
                     /locus_tag="NOB74_000878"
     tRNA            35041..35124
                     /locus_tag="NOB74_000878"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35075..35077,aa:Leu,seq:cag)
     gene            complement(35448..36086)
                     /locus_tag="NOB74_000879"
     CDS             complement(35448..36086)
                     /locus_tag="NOB74_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI1220084.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            36421..36855
                     /locus_tag="NOB74_000880"
     CDS             36421..36855
                     /locus_tag="NOB74_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI1220085.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            36878..37198
                     /locus_tag="NOB74_000881"
     CDS             36878..37198
                     /locus_tag="NOB74_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220086.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            37339..37530
                     /locus_tag="NOB74_000882"
     CDS             37339..37530
                     /locus_tag="NOB74_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220087.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(37601..37858)
                     /locus_tag="NOB74_000883"
     CDS             complement(37601..37858)
                     /locus_tag="NOB74_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HCI1220088.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            38016..38279
                     /locus_tag="NOB74_000884"
     CDS             38016..38279
                     /locus_tag="NOB74_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220089.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            38303..38491
                     /locus_tag="NOB74_000885"
     CDS             38303..38491
                     /locus_tag="NOB74_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220090.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(38574..38759)
                     /locus_tag="NOB74_000886"
     CDS             complement(38574..38759)
                     /locus_tag="NOB74_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220091.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            38974..39345
                     /locus_tag="NOB74_000887"
     CDS             38974..39345
                     /locus_tag="NOB74_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI1220092.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(39495..39567)
                     /locus_tag="NOB74_000888"
     tRNA            complement(39495..39567)
                     /locus_tag="NOB74_000888"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39532..39534),aa:Gln,seq:ctg)
     gene            complement(39613..40041)
                     /locus_tag="NOB74_000889"
     CDS             complement(39613..40041)
                     /locus_tag="NOB74_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220093.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(40101..40859)
                     /locus_tag="NOB74_000890"
     CDS             complement(40101..40859)
                     /locus_tag="NOB74_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HCI1220094.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            41154..41351
                     /locus_tag="NOB74_000891"
     CDS             41154..41351
                     /locus_tag="NOB74_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220095.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            41457..41939
                     /locus_tag="NOB74_000892"
     CDS             41457..41939
                     /locus_tag="NOB74_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220096.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(41997..42593)
                     /locus_tag="NOB74_000893"
     CDS             complement(41997..42593)
                     /locus_tag="NOB74_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI1220097.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            42980..44433
                     /locus_tag="NOB74_000894"
                     /pseudo
     CDS             42980..44433
                     /locus_tag="NOB74_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
BASE COUNT        14686 a         7621 c         9102 g        13075 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttgtttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag
    31021 gaaaccagca agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca
    31081 gtctggcaaa attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt
    31141 tcgttttctt tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat
    31201 atcccgacag caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat
    31261 ttttaacaaa atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg
    31321 ggattttttc agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag
    31381 gtgtaggttt gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga
    31441 aggaacacct tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag
    31501 ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac
    31561 gattttctag tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag
    31621 tacgaagtgt tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag
    31681 taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag
    31741 tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat
    31801 catcacggtt cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca
    31861 gtttttcatt tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga
    31921 ccaaatcggc agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga
    31981 tatttttgat tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt
    32041 cgattttgaa atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta
    32101 ctgtagaatc cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat
    32161 tttttacttc ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag
    32221 gaaccctcct gatatacata taaatattta ccatacatct atcttatcat aggattaggg
    32281 cagattctta cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat
    32341 agataaactg ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa
    32401 aattatgact gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac
    32461 cggattgacc gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc
    32521 agggatgaat gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa
    32581 gatagacaca ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct
    32641 caaagtagga aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat
    32701 gacgatgctg cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg
    32761 cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg
    32821 gatggatatc atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat
    32881 gctgattcta aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc
    32941 cttgtatacg attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag
    33001 tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact
    33061 agcaaaacgg atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa
    33121 acaagggaac atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat
    33181 cgttcatgaa atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg
    33241 ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat
    33301 aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat
    33361 tacatctaat aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt
    33421 tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat
    33481 gagcgaagca aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct
    33541 tgctgccttg gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt
    33601 gatttatgat atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac
    33661 aactatgggc tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga
    33721 agtgccagaa gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga
    33781 taagatgagc cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag
    33841 ctatgagaag caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat
    33901 aaaaggtttc tttgtttata aaattttgtc tgctatatta taagttaatt aaataaatgt
    33961 gttctattga taaaggacat tcaaatccct ttccttttgg aatccttctt ttttacatca
    34021 gtttgatttt cgtatagtat tctttctcat cttcacgata aatcgcagcc ccattttttt
    34081 gttgtgcttt aagactgcca agattttttt tatttacaga caaaagtgcc tcatcaatgc
    34141 cgattttttt tgcctcttgt agtactaatg ctaatccttg tgtggcatat ccttttttac
    34201 gataattagg ggagatgccg taaccaatat ggccagcgcc gtttcttaat gtttcgttca
    34261 gtttatggcg caaattaaaa attcctacat actcatgttc atcactttct aaaataaaga
    34321 cggttgcggg aacgtaactc tcaggaagat cgattcctaa agacgttttt tcgcattttt
    34381 ttacataatc taaaaattca gcaaatgtat agccataagc attgttgata aatccactct
    34441 catttggtcc aaagctagtt tgtagctgat aagctttctt taaatctgct tcccatagtt
    34501 tgatcagttt catcgtattc acctctttaa gtaaccttat tcatttgttt tctactatag
    34561 cactattgtt gtaaatagcc atgcctattt ttatttattg tgtcatatcg tattaagaat
    34621 catcgaacaa tacaaatatg aattacaata aaaaaattat ttgaagttcg ttcattcgtt
    34681 acttatgatc tctagaagaa agaaaacgtg aattacttca gcgtctagaa ttccagaagg
    34741 atagtaatca acagaagaaa taatcaatat ccaaatgaaa gaagatagct gaatcgagaa
    34801 aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta ctaatcccag agtcgttcgt
    34861 ttaacattga aatcgatcat atggataaaa cagatttttt caccaaccct caatagatga
    34921 tggagttgct cggatgaatt atttgtgtag atggcataag ggagggcgta cagaaatgaa
    34981 aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat cctaaactaa aagatgtgat
    35041 gcggctatgg cggaattggc agacgcgcta gcttcaggcg ctagtgaggg tgacctcgtg
    35101 gaagttcgag tcttcttagc cgcataattt gtttttttat aaagagaagg tacacctgga
    35161 gcgatgagaa agaaaataac atattatcta aaagaatata ggaaaaattt taaacaacgg
    35221 aaccagattc aaataaatca aaaaaaattt gtgtgaaggt gggacagttt aaaacctaat
    35281 agattgattc aaatagtaga tttatagatt ctgatacaag aaatactggc aaacgatagt
    35341 taaggaataa agactaaact taaactcaaa aagaggtcat gcgaaagaat aaatcgcatg
    35401 acctcttact atattttgaa tgtgtttaaa cgttcaaata atgaatctta gtaccaaccg
    35461 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    35521 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    35581 tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    35641 gcgatccatt cttttgcaga gcttgtactt gctggagtag cagcagtttc tgttacagca
    35701 ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt ccgtttgaac cgtttcttgt
    35761 acaacaggtt gttcagcttg aacaggttca gcttggactg gtgcttcttg aacggctgct
    35821 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
    35881 tagatcaggt taatatcaga aattgaattt gattctgcaa tggcattgat caaggagtta
    35941 tcaccaacgt atttttgaga aatcgttgat agagtatcac ctgattgaac ggtataagct
    36001 tcgtccgcat gagcagtcgt tcccatgaag aatgcagcgc cggcagccaa agttgttcca
    36061 aaaagtaaag ttttaagtga tgtcatgaaa aatctccttt attcgttaaa aagttttatt
    36121 tgttgtgttc aacgaggaat actttaacac gtgaaaatat ttcataggta aaagaagcat
    36181 gacaatttat gacaaatcca cgttttttgt aacagaatga tgttcgctcg atgtgaaaaa
    36241 tgatgaggaa tttcacataa tgcagaaata atgggattag aacaggtgtt ctgatgagaa
    36301 aagaaatgta taaataactt gaaagaaatt gcttttgttc atcattttat ttacatattg
    36361 cgtatatttt ttgtattttt gcttgagatg ttacaataaa agaaaaagga ggcggttcca
    36421 atgagtaaaa gataccagaa catcatggta gcagttgacg gatcaagaca atcgatcaaa
    36481 gcgttcgctg aagcccttga cttagcaaag gacaatgaag cccacttatt tatcgtgtca
    36541 atcatcaaca aagttgagct gacccatagt gcctatgcct tttcaaaaat ctatgcagat
    36601 gaaaaacaaa gaacagaagt agccatgctg aaaaaaatca atgatgccaa agagtacggc
    36661 attgctgaga tccacgcaat agttgaaact ggagatccaa gaaatttgat tgccaatgtc
    36721 atccctggac aagaaaatat tgatttgatc gttatgggag cgacaggaaa aggtgctata
    36781 caacaagcat tagttggatc gaccgcttct tatgtcgtat cacatgcccc ttgcagtgtg
    36841 ttggtcgtga agtaatgaga taagggagga atagaaaatg gttcgtcctc aagaagtccg
    36901 tgcgccaaaa gaaaaaatag aaattttagc aattattgaa gacggcacac aaacaaagaa
    36961 gggatactcg atcgctttag taaagtggaa aggaaaaaaa ggtgttgctc tgagatggga
    37021 tggagataac caacaagata aaggattccc tgtcacagct aacggttatc atccagcgtg
    37081 gtttgttctg cctgataaat ttatggaatt atacagctat gattatgcaa gagccgcagc
    37141 atcaatcaaa gcattagata aattaacaga agagcagaat gaaatggagg aaaaataaaa
    37201 aagacgaacc aatcagcctt tagaaaactg attagttcga ggagtaaaaa tgaaaaaagg
    37261 ttatttggga tgaaactaga ataatgcgta taacttaaat aaaacttaaa gcaataaaat
    37321 ggcaagaggg tgaggcaaat ggaagcagga aaagtattac aggaagtaaa agcactatgt
    37381 gcagataaaa aatatgaaga agcgaaaagc ctgatcgaaa agaacaaaga aaatttggaa
    37441 gaaaagtacc cgatcgcaca agaatttata gaattaaaac aaggaacgat ccttcaccga
    37501 ttcaaacatt tttttggtat aacagaatag aaaaaacgat taaagatcgg cagaaatttg
    37561 ctgcatcttt aatcgttttc tttttaaaca tgcgagggat tcaattctga ttcttatata
    37621 aaaaatagat ccaaataata agaaaaatta ctgaaagcgt caattcgatg atgtgtgtta
    37681 ttaatacaga cgttgtttcc caatgcctaa aagaaaaaat ttgataagta aaatatacag
    37741 caggtaaaga ggccagtaaa actgaaaact tcttttttgt ccattttatg taatagaaaa
    37801 gaatgcttat cataataaaa aaaggaatat aaaaaacaaa ttgaccgatc gcgatcatac
    37861 tattgcctcc gataaataaa gtccatgata caaaataaca ctttgtgcga aatggcgcaa
    37921 gcagttttgt ggatttatcc ggtaaaatct gtatcgattt tgaaattaga ggagaaactt
    37981 gctataatca aagtgaaaga aggagtggga ttttcatgga tcatgtagtg ttagaaatcg
    38041 atttgcattt gatcaataat attcgggtga tttactatgt tgtaagtaac agtgtcgaac
    38101 aacgtgtact gacgaataaa ataaatggta ttttagcaaa gaaagacgtt caccgattca
    38161 ataatggtga aggaagttat tatagtatcc cagtagaaaa aattatttat acgacagtca
    38221 aagtcagaga agatctagat accaaaaaag catatgaacc tatttttaca acttattgat
    38281 tgacagcaga tggaggaaaa aaatgaatcc atatgaacaa cttattcaag atttgatcga
    38341 tggaaaaatc gaaaagattg atgtaaaaag agaagaatta atggcttttc gagaagcgtg
    38401 gctgaagttg gagaatcgta aatatgtggt gggaaaagcc tcactgaacg gcaatgtgac
    38461 ttatcattac gatccgacac gtttatttta gtatgaagta ttcagaaaag aaccaaagga
    38521 ggacgatgca gcagcattgt cctcctttga ttttacaaaa gtgaaagttt tacttatttg
    38581 aatagatttt taaatttgtt tttgacactg tcgatattta catcttttaa aagattttgg
    38641 gctttctctt tataaggtcc taattgttct ttatgttctt cgataaatcg ttttgcgcca
    38701 tcgaaattgc cgttcttaat catttccttg actttttgaa ataattcttc ttgattcatt
    38761 ttgaacacat cctttgctat caacatgatt ttttacatgg acaaaacgag aaaaactgat
    38821 ttatccacac gtcaataata tcaaataacg atcattttta ctaaaaaaac actcgattct
    38881 cgcttctaaa gtaggagaaa aatctccaac ttgggacgga tggaatttct ttaactgacc
    38941 catatactga atatataaca aggaggtaga aagatgaaag tgattaaata tttgattgga
    39001 ctggcggcga ttagtggtat tttgctattt ggactgaaat attatactga aggaagttat
    39061 ggagaaatcc ctggtatact tgatcagcta aatccattag ttgaaaaagg agaggtctat
    39121 gtaaagacac aaaaaccaga ggaagtaaat gaatatggta cagcaaggta tgtgcagaaa
    39181 gctgctgatg ccaatgggaa agaacgaacg gttgaattta atggtctttc tgtgttaaaa
    39241 gaaaatcatt atttgaaaat tagcaataaa ggagcacaca tagaaacgta tgaggaagtt
    39301 cctagagaaa aagttccgga gaaagcatta gcaattattg ggtaaatcag tttttgtatt
    39361 aagaatacgc ccgattttat tattcataat ttaattatgt aaactaaata caagtagtaa
    39421 aaataataca ataatccccc tgcaaaaaga ttgttctttt acagggggtt cattttttca
    39481 gcaagcacat caaattggga tggcagggtt cgaacctaca attgcttgat tcagagtcaa
    39541 gtgccttacc agtttggcta catcccattt attcaacaaa ataatcatag cactttccta
    39601 aaaaaacgca agttattttt cttgatcgga tagttgttgc tttactcgta aaaggcggcg
    39661 tactagtttc ttttctaatc cagcaggaag ggcaatcagt tctgctactg acaagacggt
    39721 gtccaataac tgatattctt tgacaggttc attcataata tgatagatgt ttgctaaacg
    39781 ttcaatatat tcaaagcgag tatactctgt tcgagcaatt agaaatttca ataaatcggt
    39841 ggctttctcg tactcttgat ctgcgtaata aacaagagat tgacgataca atttgatttc
    39901 cagttcattg agggtagcag gtctgcgacg ctcgttccac tcattaatag agactttacc
    39961 ttgaacattt cccttgcagt cacggacaaa aataatcgga atttcatttg gatccatttt
    40021 tttatgtgtg aatttttcca ttatctacgc tcccttcaaa ggtttggtat cttgagtata
    40081 agggattttt gtttgaatta ctagcttttc tccaaagtta gcatctgtcc acccattgca
    40141 gtgaaaatcg ccgaaaaatc gttgatcggt actgctcgat tttttacacc atagggatcg
    40201 ttgacataaa tattttcttt gtcatatcca gtgactacac aagcatgaac aagaggagtg
    40261 actcttactt ctccattatt tgtggtccaa gtcataaaat cagtttcatc tgggacttca
    40321 aaattgatag tcacagaagt ccagacagga tttcctttag atagtgcttt tttgatatca
    40381 tcgagttgag catcggtttt tggaaaagtg tgataatccg tttggacgat ttgctgagca
    40441 agggaggcaa ctgggggaac atagacgacc atagcccagt ctccgccact gatatcacca
    40501 acaaatcctt cattaggatc gccatgagtc ccatctgcat tgaaaacagg gacgtaatcc
    40561 aattgctcag ctaactggtt tttagttgtt tcataaccat aaaaagataa aagcatagaa
    40621 agcgaagtga cttcacagcc attttctaaa gaaggagaat caaactggct ctctaatgga
    40681 acatctagta aaacttctgc tttctctttt gtctttttcg ttttttgtgt tgaacttttt
    40741 tgtgcagtgt tcattgtatg ttctggagaa tggatatgta ggtaataact tgtaccgctt
    40801 aataaaagag cagctgtgcc ccctagaaac aatagttttt tgaacgtttt tttcttcatt
    40861 tgaaatctcc cttttcagct gtttatcttt cctattataa atgtattttt attggaaatg
    40921 gaagtattat attttaatat gtaggaaata attagttttt aaggaatatg ttttaatttt
    40981 ttgaaaaaaa ttcttctaaa tacaacagct gttttaattg tgaaaacgaa aacagtacgc
    41041 tataatgcct gtaaggttga tttttaactg taaataaaaa tcaatgagtt aaatctccaa
    41101 agaaatagca gtggtaatgt ggagaaaagt tccagcagtt taggaggatt ttgatgacgg
    41161 aagaaatgat taatttagga gaacaatatg catgcaaacc aattggtttt acaaaaacgg
    41221 tcattggtga agttgtatca aaaatgacaa actgcgccgt ggtcaaagtt gcccaatgtg
    41281 ctgcagagga ccaagaatta ttagatgaaa aagcaagcat ggttgttgca aaatatgata
    41341 catttgaata aagaaaacaa ttggacgtgc ggcgtgctgc aagtccaatt tctttgagaa
    41401 ggtaaatcag tattcttttc ctattttctg gagaagaaaa agcgaggcga gttgtcatgg
    41461 taacattctt tacggttcta ttgtttttat tcgttgttgt gatgttttta tttctttggc
    41521 tggttcgaaa agaaattatt tatcggactg tgcgaaatcg atgggtctac ttggtgatac
    41581 ccttcttagt gtcactagtc atttggtata cactcatcag tcatcctaca gcagatgaat
    41641 tggcaaaagg gatcttgtca gcaatgattt ttattagttt tttgttggac agtagaggaa
    41701 tcacagaaga aggacttgtt ttgaatagct ttgacaaaaa aggtgttcct ttttctgaga
    41761 tcaataaaat tgtattatat cagccaaaag gttctaaaat cgtaaaaatg aattttttcc
    41821 gaaacggatg gcgaggaccg atgctgaaat tttctgcatc attagaagaa ttagttccat
    41881 ttttgtccca acgcttaaac gatgaggcag agattgatat tatgattgat ccagaataaa
    41941 aacagaggtt gcgacaagat gtttgtcaca acctctgttt tttatttcaa ataaaattat
    42001 ccaaatacgc ggaagcgatc ggcatcgttc atgtattctt tttcctcagc cggtgtttct
    42061 ggtgaaccga atactaattg cgaacgtagt ttccagtttg aagggatatt ccattctttt
    42121 gcaactgctt cgtcaataac tgggttgtaa tgttgcaagt ttgcgcccaa tcctttatca
    42181 actaatgcta cccaagtatt agctgttgcg attccgtttg attgttctga ccaatctggg
    42241 aagttgtctg catataattc aaattgttct tgtagacctt ttaccacgtc agtatctttg
    42301 aagaataata ctgtaccata accatttttg aaaccagcta atttgttttg tgtatttggg
    42361 aaagcttctg ctggagtcaa tgggcgaagt gcttcttcag tgatttccca aagtttttca
    42421 tgtgcatctc cgaaaaggat aactgcgcgt gttgattgag cattgaaagc agttgggctt
    42481 tctttaattg cttctttgat caaagttgtt aattcttcat tagaaagtga aacattacgt
    42541 cctagatgat agattgaacg gcggtttttc aaagtgtcag taaaagttgt cataataaaa
    42601 tttctccttt gatttgcgtt ttgcattttt ttaattgatt acgaaatgaa gtatagcacc
    42661 ttacaaaaag taagtaaaca gatatgctca caaaaaataa gcgaagttca aaaaacaatt
    42721 ttaataagaa aaatcgttat gtaaggattt tcttagttat cgctttcatt gttgtgtttt
    42781 aggaattttt gcttatttga aaaaaacagc tgatatataa ttattaaatc tctatcttct
    42841 tttttttatg atattgccat taaaaattac ttgcttttat agaaaattag tttatatttc
    42901 ttaaataagt tttttagtta aatttttcgg taaagatgta taatattttc tgaaaattta
    42961 aagaattggg gtatagatta tggaaaaaca gcaagacaag ggcttcttcg ggcagccgaa
    43021 gggattgtca actttgttct tcactgagat gtgggaacga tttagttatt acggtatgcg
    43081 tgcattactt atctattata tgtacgatac agttgccaac gggggacttg gattaccacg
    43141 agcaacagca ttagctatca tgtcgatcta cggatctttg atctacatgt ctagtatcgt
    43201 cggcggatgg gtatctgacc gagtgttagg agcaaaacgc actgtattct tcggtggagt
    43261 tttcattatg cttggccaca tcgtcttggc tttaccattt ggtgtaagta cattgtttgt
    43321 ttcgatggca ttgattatta tcggaaccgc ctttttgaaa ccaaatgttt ctggcatggt
    43381 cggacatctt tattcaaaga ctgacttgcg aagagatgca ggattttcga ttttttacat
    43441 gggtgtcaac ttaggggcat tattagcagt acaatcggtc aagaatataa ctatcattta
    43501 gggttctctt tagctgctat tgggatgttc tttggattat tacaatacat catccaagga
    43561 cgcaagacat tagacggagt gggtacaaca ccgccgaatc ctttgacaac tgaagaacgt
    43621 aaaggattca tccgtaactt gatcatcgca cttgttgtta tcgctgcagt attcggcggg
    43681 gcacaactaa ctggtcatct gacaattgac ttttttgtca atacaatcag tgtattgggg
    43741 attatcttac cgttgtatta ctttatcaaa atgctgactt caaaagatgt aactgctgaa
    43801 gaaaaaccaa gagtatgggc ttatatccca ttattccttg cagcaatcat tttctggtca
    43861 ttacaagaac aaggttcatc tatcttagct ttatttgcta gtgaacgtac acaatctacg
    43921 ctatttggtg taacgatcca agcaagctgg tatcaatcat tgaatccaat tttcatcttt
    43981 attctgacac cagtattcgt aacgatgtgg acgaaacttg gtgaacgtca accatctaca
    44041 gtagtgaaat tctctcttgg acttttattt gcaggattat cgtacttgct attgatgttg
    44101 ccgggtatgc tttatggtac aagtggaaaa gtaagtccat tgtggttgtt gggaagtttc
    44161 ttcatcgtgg ttattgctga attgtgtctt tcaccagttg gtttgtctgt gacaacaaaa
    44221 ttagcaccac gagcatttga atcacaaaca atcgctattt ggttcttagc tgatgcttct
    44281 tcacaagcaa tcaatgcaca aattgcacgc ttctacacac cgggaacaga atctgcttac
    44341 ttcggtatta tcggtgcagt agcaatcgtc ggtggtatct tgctatttac tgtgaaagaa
    44401 ccaatcaaaa aactaatggg ctctattcat taatcaatga acataaaaac aggaattgct
    44461 tatttgcagc agttcctgtt tttt
//
LOCUS       DAIGWC010000016        43403 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.016, whole genome shotgun sequence.
ACCESSION   DAIGWC010000016 DAIGWC010000000
VERSION     DAIGWC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.016"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..210)
                     /locus_tag="NOB74_000895"
     CDS             complement(<1..210)
                     /locus_tag="NOB74_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI1220098.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
     gene            complement(309..623)
                     /locus_tag="NOB74_000896"
     CDS             complement(309..623)
                     /locus_tag="NOB74_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220099.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(691..1185)
                     /locus_tag="NOB74_000897"
     CDS             complement(691..1185)
                     /locus_tag="NOB74_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220100.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            complement(1178..1492)
                     /locus_tag="NOB74_000898"
     CDS             complement(1178..1492)
                     /locus_tag="NOB74_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220101.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(1708..3099)
                     /locus_tag="NOB74_000899"
     CDS             complement(1708..3099)
                     /locus_tag="NOB74_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI1220102.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="NOB74_000900"
     CDS             complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="NOB74_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HCI1220103.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(3699..3896)
                     /locus_tag="NOB74_000901"
     CDS             complement(3699..3896)
                     /locus_tag="NOB74_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220104.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            complement(3887..6565)
                     /locus_tag="NOB74_000902"
     CDS             complement(3887..6565)
                     /locus_tag="NOB74_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220105.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            complement(6552..6770)
                     /locus_tag="NOB74_000903"
     CDS             complement(6552..6770)
                     /locus_tag="NOB74_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220106.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            complement(6846..7898)
                     /locus_tag="NOB74_000904"
     CDS             complement(6846..7898)
                     /locus_tag="NOB74_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI1220107.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            complement(8051..8377)
                     /locus_tag="NOB74_000905"
     CDS             complement(8051..8377)
                     /locus_tag="NOB74_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220108.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(8389..8589)
                     /locus_tag="NOB74_000906"
     CDS             complement(8389..8589)
                     /locus_tag="NOB74_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220109.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            8712..9314
                     /locus_tag="NOB74_000907"
     CDS             8712..9314
                     /locus_tag="NOB74_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1220110.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            9369..10535
                     /locus_tag="NOB74_000908"
     CDS             9369..10535
                     /locus_tag="NOB74_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1220111.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            complement(10624..11016)
                     /gene="rpsI"
                     /locus_tag="NOB74_000909"
     CDS             complement(10624..11016)
                     /gene="rpsI"
                     /locus_tag="NOB74_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCI1220112.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(11032..11475)
                     /gene="rplM"
                     /locus_tag="NOB74_000910"
     CDS             complement(11032..11475)
                     /gene="rplM"
                     /locus_tag="NOB74_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HCI1220113.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(11994..12461)
                     /locus_tag="NOB74_000911"
     CDS             complement(11994..12461)
                     /locus_tag="NOB74_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HCI1220114.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(12581..14119)
                     /locus_tag="NOB74_000912"
     CDS             complement(12581..14119)
                     /locus_tag="NOB74_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HCI1220115.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            14199..14885
                     /locus_tag="NOB74_000913"
     CDS             14199..14885
                     /locus_tag="NOB74_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HCI1220116.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(15086..15613)
                     /gene="msrA"
                     /locus_tag="NOB74_000914"
     CDS             complement(15086..15613)
                     /gene="msrA"
                     /locus_tag="NOB74_000914"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI1220117.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(15697..16374)
                     /gene="pgmB"
                     /locus_tag="NOB74_000915"
     CDS             complement(15697..16374)
                     /gene="pgmB"
                     /locus_tag="NOB74_000915"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCI1220118.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(16371..17499)
                     /locus_tag="NOB74_000916"
                     /pseudo
     CDS             complement(16371..17499)
                     /locus_tag="NOB74_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(17499..19682)
                     /locus_tag="NOB74_000917"
     CDS             complement(17499..19682)
                     /locus_tag="NOB74_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCI1220119.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(19679..20704)
                     /locus_tag="NOB74_000918"
     CDS             complement(19679..20704)
                     /locus_tag="NOB74_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1220120.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(20749..21576)
                     /locus_tag="NOB74_000919"
     CDS             complement(20749..21576)
                     /locus_tag="NOB74_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI1220121.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(21573..22640)
                     /locus_tag="NOB74_000920"
     CDS             complement(21573..22640)
                     /locus_tag="NOB74_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HCI1220122.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(22666..23502)
                     /locus_tag="NOB74_000921"
     CDS             complement(22666..23502)
                     /locus_tag="NOB74_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1220123.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(23499..24368)
                     /locus_tag="NOB74_000922"
     CDS             complement(23499..24368)
                     /locus_tag="NOB74_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1220124.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(24438..25721)
                     /locus_tag="NOB74_000923"
     CDS             complement(24438..25721)
                     /locus_tag="NOB74_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCI1220125.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(25735..27420)
                     /locus_tag="NOB74_000924"
     CDS             complement(25735..27420)
                     /locus_tag="NOB74_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HCI1220126.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            27695..28720
                     /locus_tag="NOB74_000925"
     CDS             27695..28720
                     /locus_tag="NOB74_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1220127.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(29315..32989)
                     /gene="rpoC"
                     /locus_tag="NOB74_000926"
     CDS             complement(29315..32989)
                     /gene="rpoC"
                     /locus_tag="NOB74_000926"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HCI1220128.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(33047..36664)
                     /gene="rpoB"
                     /locus_tag="NOB74_000927"
     CDS             complement(33047..36664)
                     /gene="rpoB"
                     /locus_tag="NOB74_000927"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCI1220129.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            37392..38360
                     /locus_tag="NOB74_000928"
     CDS             37392..38360
                     /locus_tag="NOB74_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1220130.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            38378..39283
                     /locus_tag="NOB74_000929"
     CDS             38378..39283
                     /locus_tag="NOB74_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220131.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            39280..40086
                     /locus_tag="NOB74_000930"
     CDS             39280..40086
                     /locus_tag="NOB74_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1220132.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            40222..41211
                     /locus_tag="NOB74_000931"
     CDS             40222..41211
                     /locus_tag="NOB74_000931"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HCI1220133.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(41528..42052)
                     /locus_tag="NOB74_000932"
     CDS             complement(41528..42052)
                     /locus_tag="NOB74_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HCI1220134.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            42339..>43403
                     /gene="scm"
                     /locus_tag="NOB74_000933"
     CDS             42339..>43403
                     /gene="scm"
                     /locus_tag="NOB74_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HCI1220135.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        12446 a         9026 c         7629 g        14302 t
ORIGIN      
        1 taaatcagat acataagccc atgtacccgt tcgttgtaaa taaagttctt cttgtaacaa
       61 ctcccatttt ctcttagaaa tcataatgac gccatcgttc aatccatttt tagaatccct
      121 agtaatttct atttcagaat ttgaatgaac tacttcttgc aacactttac ctatattttc
      181 tttgaagttt gttggagtaa tagtatccaa aatgaatacc tctcttctct atacctctat
      241 tatgaagtgc ccataaaata aagcaagcgt tgaggaataa ttctatcaac acttgcttta
      301 ttaagctttc attttgtagt ttgactaaaa ccaataatct tatttctaaa ctctcgaaaa
      361 acttcttgtg gttgataata gtctggatct atttcaaatg tttgtgagaa taattcattg
      421 aatttttcta ctgaaataat gattttacca ttcttctctc gactgttttc tattatttct
      481 gcttctaatt caaataaatc tagtgacgaa ctaaaatcat aaatcatgtc atattgaata
      541 aaaaaatcaa gaaaaagttg ctcaaactct tccttattta tcactaatgt ttcaaacgga
      601 acaactttat tttcctcagc cattctccca gttccatttt caaaaatcac aaaactgata
      661 ttaccttaaa aactactaac aaaataaaac ttataaagta aatggcaacc caactatgta
      721 accattctct ctacgtacta cgatttggta gtcctgcctt tcaatcggta attcataata
      781 gtaatttact gtttcttctt tgccactttc aatatactct ggattatcca atatcatatc
      841 atactcataa agttcttcac catccttatt ttcaatcgac cattgttgtg gacgtatcgg
      901 attttctgta tcatttataa gtgtataggt cacttgtaat acacgatcat gttgtgcaaa
      961 ttcatttctt ttttcggtca cttcaatatt tttaaatgtt agttcaaccc catctgcctg
     1021 ataagtttca cctattttta aatcttttgt tacaattttt attggctttt cttctggaaa
     1081 atgtctggct ttaattgtta gataacttcc aaaaagaatc aatcctagta gcactaaaag
     1141 aattccttta acgagccact gaaacgggaa gtaaacttta aacatctttt ttctcctccg
     1201 ttttgtattt gttttttaga gaatacgata acttttgatc aatgtcatcc agcttttcaa
     1261 ttacttcatt acttatcatt gattctagtt ctgaaatttt ttgttcaaat ttaatgcttt
     1321 caggatcatt aaatttatta tttgatggac tagctaacac tggtaaattt gaaaccataa
     1381 cacgaaacat atttgccttt gaaccaaaaa ttcctttgtt ttggttgtaa aaattgttga
     1441 atatttcttt agtttcttct gaagccgaga ctttaaaata tggatagttc atttttttct
     1501 tccacctttc tttttttggg agggagtctg tagggagctt gctccctcag agatttaccc
     1561 gccatctgac ttgccagaaa gtagcctagc gtgagcgggg cggattgact ggcaagtaga
     1621 tgggtagctg gcgtatgtcc taaaaactgc ttctttccaa gcaactcttc ataggcaaaa
     1681 aactggaaag tccactaaca agcccattca gaattccatt tcaaaatttt gttgcctttt
     1741 ttgctgattt tcaatcattt gttgtgtgaa ttcataatcc tttttagcac gatacatttt
     1801 tacatcgtca ttcattatgc gactgatttg atagtgaatc tgtttagcag aaggtgtatg
     1861 agaacaattt tcaaaaccct ttgccggtag aaataactct ttctgatcag tctttttaat
     1921 agaaattgtt ttacttttcg cactacgtaa agtttgagga ttcacatccg tatgaagttt
     1981 aatcgtgtat tcttgatcat cttctaaaga cattgtattt acaaaatgct tgtctacctc
     2041 tcgcaagaag tcatcatatt taatgaattt ttcatcgcct tcacggtcgc taaattgctt
     2101 ttgtgcgatg gaatctaatt ccacaaacgg tacatttaac tcaccagttt tgtaatttac
     2161 tccactaatt agcgacataa cttgctctct ttccatatta aaaaaatttt ttatatgtga
     2221 ttcttctaaa ttcttttcaa gttgttcaga aacagattca aatgaatatc ttttccctaa
     2281 ctttcttgca ctaaaagtac gttcgacata ctgacttttt tcttttctag attgtttatc
     2341 tcttcctaaa gtaattaact cacctctacg ctcatagaaa tttacacctt gtttgtaaag
     2401 aacatagcca agtttgttat ttgtttttga aaattgataa acttcaatgt tatattcttt
     2461 tgccaaatga tccgaaaaat cttcaaaaga attcacttcg catttttcca acgttgcttc
     2521 gatcgcattt tgcacaaact cttgataatt aatttttcca tatttcatct tagaaggatc
     2581 gtttgaataa agattggttc tcttttctaa gttttcatag tactcattat tcactgattc
     2641 aagaccatgt tcattgagga cttgatcgtt aatttttcgc attagttcta aatctttagg
     2701 gtcaatacgc aaccttttac atgtttccat gttaatatta ttaatgacaa gatgactatg
     2761 aaaatgatct ttatcattgt gacttgcaac aatgatttgc gaatttggaa aagctttctc
     2821 tgcaaattcg acagctattt cgtgcatttt atcaatactt aactctttag aagtactctt
     2881 atcaaacgaa tgaataacat gaaacgcttg tgctatatct ttagatttat tcatcttggt
     2941 acgtactaaa ttcatttctt gcagtgcttc ctcactatca tcactacaat ttattcctga
     3001 gactgcaaca catttttctt tttttgaagg attagctgca tattgtaata gcgaggataa
     3061 atttttcttg cgtcctttcg atgttatagt agctcccaaa gttgtttcac ctcatctttt
     3121 aaacttgcaa taatctgaat tgagtgaatt aaattccgat caactttttg ggaatactct
     3181 tctttcgtac ccggtctagt ttgcttttct atccaatatt cgaaatattc tttttctact
     3241 tctgataatt taaaaaaaga gggggcactc cgattggact ccaaaaaaat gtcatctgga
     3301 taactaatca tcaacttttt tgctatgcta ttcgcaagtt catctttaaa aatgttgtaa
     3361 cggctagcat caaaactaaa atgtaggctc ttttcttttt tatcttcaga ttcttctcta
     3421 aaatatttag caatgatatt taatgccttt accgcttgat tcaaattgtt accaatttga
     3481 tttaactgtt tggttaaaac taccctatca tcttcagcta acaacggcgg ttcatatttg
     3541 agtcccttta accgctcacg gcaaacgtct gctctagaaa ttcccctttg ttttgcaatc
     3601 aatgtcagtt caagataagt ctttttatcg acacgaaaat ttaaggcctc actatgtttg
     3661 cgattttttt cgtacatttt ttgtttatca tccattgatt atcccctcac atttttttct
     3721 agagagcaac atttgaaatt gctctctatt tcatttttca tctttaattc ttcttgaatc
     3781 atcagttcaa tataattagt gaccgtgatt ttttcatttg ttgcgttctt tactgattca
     3841 cataattcgt caagttctaa gaaatcatgc gtactaatct ttagaattaa ttgcatgaca
     3901 atccccccct tttatttctt aataaattat cgaaaagtgg attaggatca ttaagtgtat
     3961 ctctgaataa ctcattgtct tcataagtga atcttcgtct tgattttgat cccttatcat
     4021 tttcacggat ttcactatca ataatcactg tttcatgatt tgaatcaaat tttttcgctg
     4081 actttctgtc ttcaacgata ttgatttttt gtgttttttc tttcatttct ccactatctt
     4141 tttgaatgtt ctcccgaaca tctactgttt tgaatccttg actacttgta gaactttgta
     4201 cattttctcg gacatctact gtttttggtt gacttgcact gctaccttgc acattctctc
     4261 ggacatccac tgatttaaac ccttgactac ttgtagaatt ttgtacattt tctcgaacat
     4321 ctactgtttt tggttgactt gtactgctac tttgcagatt ttctcgaaca tcaattgtct
     4381 tagtaccttg agcatttgaa gaactttgta aattctctct tacatcaaca ttccgtccaa
     4441 catgaccatt cagtgaacct tgaatatttt ctcggacatc tactgatcgg ccaccatgac
     4501 tacttgtaga attttgtgga ttttctttga ctaatttttc taatcctgta tttgaatttt
     4561 tagcttcttg aattctttct ttggtcaacg cttcttttcc gtcaatatta gcgcctgtcc
     4621 gcccttctac acgtttcctt aacattattt cctcgcgatt cattgcttca ggcgtgtatt
     4681 tcgcttcatg acgcttctga ttaattaatt cttcagcaga cttagcttga ccgtgcatag
     4741 catttttacg ttcttcaata tcttgttgga ctttttgctg aattgcgctt gcaggattat
     4801 tattcgattc agcattattt ttcattgctt cacgcatacg ttcagaacta gacataattc
     4861 tatcggcatt ttcaacttta gcaccatctt ttctatctga aagacgtgtt ggcacggaat
     4921 cagcatattt tccagtttca tcttctttat ttttagctaa cataggtttg ctatttttat
     4981 taatagcgga cactgtacca tcatctaaac cttctttaaa cttattcttg gtatcattag
     5041 ctatatcacg catactctta aatggttttg ttgctctttc actagccatt gtagctccat
     5101 ctgaagctaa accggataat ccacgttcat gggcatatcc caaagctctt ccagttttgc
     5161 cagctttttt tgatagagtt tcgccgaaat tcttttctgg ttttcgatct tctccttctc
     5221 cgcttccttt agcacgatta aatccatttg atccttttct aaacagcatt gcgcccattc
     5281 caaaagcaga agcaagttgc ccatagcctt ctttgagtcc aatatcaaca ccaaagtatc
     5341 tcatgactgt tccactgcct ttgattaaaa caaaaacggc acagatataa gcaattgttt
     5401 ttataaaaat atttgttgag ataccttgtc ctgagttcag aaaattgata aacatagcaa
     5461 acattgataa cccaaatcct tgaaacccaa cagttaagta acattgtaga atatctgata
     5521 gaacaacttt tgaacgctgt cctgtctcaa tatctgttgc aaaaacaaga acacctaaca
     5581 cacgtttaaa tgcaagttct agtattgctg taatgatcac aaacgcgctg aacacatagg
     5641 cgattgctaa cgctgtcaac ccaattgaaa tcccccatag atttgcttgg tatcggtaat
     5701 agcctgattt caagctatca gaaaatgttg ataagaagtt gtcagaaaac tttgtagcaa
     5761 caaattcatt attagaattt tcaactaatt cataacgaag attgtccgca attggatttt
     5821 ctttttccaa tttatcaatc actttatccg ttaacacttg tgtgagatcc gtctgttgaa
     5881 aattttttcg tgttaaatta tttcgatcct ccgttttatc aatgcttgag tactgatctg
     5941 ttttattaat atatgctaaa tctgttactc cttgttttat caatgaccaa gcgactccgt
     6001 catctgaatt tgtaatcgta gtagagtcct tataaaatgt tttagcaaat tgaataccac
     6061 tagaaatcat ggttggcatt aaaagtatta atgctataga catcactacg ttcattccaa
     6121 ccgattttaa atccactgtt ccttttccag taatcatttt gtaaccaaca aacatcaatg
     6181 aaaggatcat taatccaatg acaattgtat ttacggctga ttgataaaca ttatttagcc
     6241 ctgtactttc aatgaaattg aacaaatcca gcacatctgg aatcatattt tgaatcgaat
     6301 ctgtcacagt aaacatgcct tttaccacag cccatccgag ccaaatcccg aactgactaa
     6361 ggaaatctcc attgtacttt tttaggtaag gtctataaag agaattattc aaaaactctg
     6421 tttgactttt tgtgtcatca aaccaattga aaatactcgc atgagcaata ttacttgtaa
     6481 aaataatcat agctatcaga acaagaaaat taacaaccaa ccaatttatt tttttattgg
     6541 caatcttttt ttcaattatt ttcatcgtta cctcccttag cccattttct gaggctctca
     6601 gagagcttct gagccatttt ttgattaatt atgacatgag ttacacaatt atcattttca
     6661 gctcttaaat cgagaactat agtgttgaag caaatagtct cgattaattc gagactatct
     6721 gtattttgat ctagacacca aacttgatct attaaacgat ttttaatcaa aataacccct
     6781 cctatattca aagttctcaa atgaagtgga gatacccctc catttcattt gactcaattc
     6841 tattcttatt gcttatctat tccttcgctg atttgcaatt caattagttc taacgcttta
     6901 ttttttagag aagcaaagat ataatcgtct ttttgtttga tacgatgatc tgtttttgct
     6961 cttcgtatca agtcacgtaa agtcattgat agctgttctc taacatgatc tacaaaatac
     7021 ttgttattac aaatttcata gataattttc agttgaattt tttgttcttt ttcagcagat
     7081 ctaatcgcat atttgaattt tttgtaccag ttgtcgaatt gacgataatc actattgcta
     7141 gccagtttta agcaattcac aatactttct ccccatattt gtttaagaag attttcttca
     7201 ataaatgttt cgatcaattc ttcatctaat ttattatttt tagttgaaag tgattcaaga
     7261 agatcatcat tatgtgattc tttaatatct ttactatctt tataagactt atataattct
     7321 agttcatttt ttgaactatc agcaaaattg tttttgtctc ttgttttcat tgatgtgtcg
     7381 catagttcaa attttgaact atcaacagaa tattgatttg ttccatagtt caaattttga
     7441 actatcaagt ttttttgtct attttcttga tgggttatct tattaatttt ataaacatca
     7501 tctttgcaca gaacaggctt taacaaataa taaaaatttg ggaacatttg cattttactt
     7561 ttattgaagc cattttttct tttcacaaga agtttaactt tttgaagttc atctagtgct
     7621 gataagattg tattttttga cattcccgaa atttctacga gatttttgat ttcaaatatc
     7681 aaaaaaattt tttgattctc atcatacaag ttatttttca atgaaagtct atttctatct
     7741 tttagtaaca tataaactaa cttagaactt agtttcattt tcttatattt ttcatttacg
     7801 tttaaaaaaa taggatattg atagtataat tctgcatata tatcagaatt agaatagcct
     7861 tgcttttcaa ctaagctttc aacttctttt tcattcattg tcacacctgc ttctgatttt
     7921 atttgctata atagattcaa ataaagtttt ctcagaactt tattattgag tgttcccccg
     7981 atctgcaaac tgacgggaac actcttttta attttttcta cttcatcaaa tttaaaaaac
     8041 gaggtgtttt ttaaatttga tgactcaata tccatttttt gcattcttct tttgaaaaca
     8101 actccatttt ttctaataaa ataactggca atcccattct tttaaatttc aaaaaagttg
     8161 tatatgatac attcaaatat ttagccatct cttttccttt tagaaatggt ctttctaatc
     8221 cggtatcaat tcttgcttga tcaatagcct cttttgtcat ttcaaaaaca taatttttca
     8281 attgattcgt ttgttgttta tctaacatta ctgtaattcc tgcatccatt atttttctcc
     8341 tctcattttc tatttcttca atcagccaac tcgccaagtt gtatttattt agattttcaa
     8401 atcattaagt aaccaattta ccaacttttg ataagtagat gctctaatac tttctttgct
     8461 cccattttcg attttgacat atgttttccg atttatacct atcaattttg ctgcatcgtt
     8521 tttagtaagt ataagatcgg ctctatgtct tcttaagctt ctaatgaatt gatcattaag
     8581 agttatcatt cagcgcctcc tttcaaatta ttcactttgt ggtttttatc ttaataagca
     8641 cattttaaac cacaaaacga gtaatatcaa ttaaaatatt actcaatttg tggttttcat
     8701 gctataatag tttggaattt actatagggg gcgttacttt gaatagaata aaattttata
     8761 ttgattccag taaaaagacc attaaacaaa ttagtacaga aactggtatt aactatacaa
     8821 ctcttacgaa ctattaccgt ggtgagcgaa atcctagaaa tactgaaaca tggaatatcc
     8881 ttgctgatta tttccatgtt cctgtaagtt atttgatggg attagacgaa acaaattcca
     8941 tagaacaacc taatcttgat agaataaaaa ctgctcgttt agaaaaaaag gacaaaatag
     9001 tcaagaatat tgccagtctt gactcagatt attttactga attatctaat ctatactttt
     9061 ccatgacttc tttacttgaa gtcaaacttc aagaagatga ctccgacttt ctttttttaa
     9121 aaagtattct agaggactcc tttgaataca cgattctatt tgccaaacaa aagaagttta
     9181 ttaataaagc tttaaactta aatatcgatg aaagaaaaga gttagaatct gagttatttg
     9241 gcaacttaac ccaagtacag gttaacaatc taaaaagaga gataacagct cgattaatat
     9301 caaaacttca ataaaactaa ttattcaatc agccaactcg ccaagttatc agattggaga
     9361 gattagttat gtcaatacaa aagtacacaa caaaaagcgg tgcacgatat agtgtccgct
     9421 tgtatgttcg taaagatgaa aatggaaagc aagaatacta tgtaaaaaaa gggtttaaaa
     9481 ctgaaaaaga agccaagtta cacgaagcaa gaaaaaaggt cgagattgaa gataccggct
     9541 atcataagcc ttctaatgac ttgtttataa cagtgtatga agaatggttg ccttcttata
     9601 ggaatcgtgt acaagaaacg acatatcaac gtacaaaaga ccttttccgc ttgcatatac
     9661 taccaaaatt cgggaataag tccatttcta agattactcc tgttcactgt cagaatgcag
     9721 tcaatgaatg ggctttaaaa ttcaagaata tcaaacagct taagtcttac agctctcaaa
     9781 tatttgagta tgccattttt gcagagctat tacaccgaaa tcctatggca aatacaaatc
     9841 taccaaagcg ggaaaagaaa gaaaatgaaa attacttttc attagaagaa ctaaaagctt
     9901 tttgggatat tctcaataaa gaagagcctt taaaacatat tttaatcttc cagcttttga
     9961 ttactactgg tatacgtaaa ggagagctag ctgctcttca ttggtctgac atttattttg
    10021 aagaacagct aatgtatgtt agaaagagct atgcaactat tcgaaatgaa gagaagaatg
    10081 caagaagaaa aactgtcagg attcaaaaaa atacaaaaaa tatatcttcc gaacgaatat
    10141 taccaattga tgcacaaact attgaaatgt taaaaatctg gaaaaaagaa caagctcgag
    10201 agcttttgca gtttggcata aatacaaata caaaaaatca acttatcttt acctatgtaa
    10261 atgcagacgg tgacattaat caacctttgc atgcggacta ttcaaataat atattgaaac
    10321 gtttagagaa gaaatataaa tttaagcacg ttactattca tggattccgg cacactcacg
    10381 ctactcttct actagaaggt ggagcaagta tcaaagaaac acaagatcga ttgggtcata
    10441 aaaatgctga aactaccctt aacacttatt ctcatgttac tgaaaaagct caacgaaatg
    10501 cgttagaaaa attcattgct tacactggtt tataatattg tcattacctt tctcattacc
    10561 agaacgaaaa aaagacacct tctcgcaatg agaaagtgtc tgaaatcgtt ggtataacaa
    10621 cgattaacgt tttgaaaact gtgaagcttt acgtgctttc ttaagacctg gttttttacg
    10681 ttcgaccata cgtgcgtcac gagtaagtaa gccagcacgt ttaagagcta aacggaagtc
    10741 aggatcaact tctagcaatg cacgagcgat accatgacgg atagctcctg attgtccagc
    10801 gtatcctccg ccgtttacgt taacaaatac gtcatatgcg ccttttgttt cagtaacagc
    10861 gaaaggttga ttgattactt cacgcaagtc agcatgtgga atgtattctt caacatcttt
    10921 tttatttaca gtaattttgc cagttcctgg tactagacgt acgcgagcaa ctgcgttttt
    10981 acgacggcct gtgccgatat attgaacttg tgccaatgaa attccctcct attagattaa
    11041 gtttgtgatg tctaaaactt ctggttgttg tgctgcatgt ggatgttctg ctccaccgta
    11101 tacgttcaat tttgtaaatt gtttgcggcc taaagtgttt ttaggaagca taccttttac
    11161 agaagtttcg atcaaacgac gagaattttt agcacgcaat tcgccagcag tgattgattt
    11221 caatcctcct gggtagttgc tgtgacggta ataaattttg tcagtcgctt ttttacctgt
    11281 taatttcact ttgtctgcat tgatgacgat gacgaaatcg ccagtatcca aatgaggtgt
    11341 gaaagttggt ttatttttac cacgtagtac agatgcaaca actgttgaaa gacgtcccaa
    11401 tggaacatca gttgcgtcta ctacatacca tttacgttct acttcgcctg gtttggccat
    11461 atatgttgta cgcacgttat tttcctccaa tttaagttct gatgtttgac atacacttcg
    11521 agtttccggg gctctttgtg gggcaaacaa taccatttaa catattaccc gctaatctag
    11581 tcaatgtcaa cgtttttctg cttgattgaa aaatttatat gaaactttac ttcttttctt
    11641 tcttttatat aaaagggtcg tttcctgtca aaatgaaaaa caaaaagagg ctgtgacaaa
    11701 agtcttgtca caacccctta ttttgaataa acggtgttct cctgccaact cctcggtcac
    11761 aagtcacaat atccataaaa cataagaagc tgttttttaa aattgtttct tgtgactcgg
    11821 agctgaacgg caggcttaca acctcttggt aaacggtgtt caatcagctg accctcggta
    11881 ttagctcaaa aaacggcaaa atatgaggaa ctattttgac gtttgtttct ctaatactca
    11941 ggtcaaaacg ctgatttcac aacctctttt tcggtcaagt tcaacaacag tttttacgcg
    12001 tcgatctctg gcgctttgcc caaatgagct tggatcatcc agatacgttt ttctgtggct
    12061 gttttgaatt cgataaagat atcttgtgtt ggatcgtcgc cttcttctcc agaaacttcg
    12121 attccttttt ggtaaagatc tgctagataa cgatagcctg caacaagtgt ttccaaacgt
    12181 tctggaatag tacgatccca gcggccaatt tcatcaggga tttttgtgtt atctgcaaat
    12241 tcacgcaatg tagaataagg tgaaccgtct aatgtgatca agcgttcgga tacttcatct
    12301 aactgagcgt tcaaatcatc catgaactca tccatcattg ggtgcaatgt aaggaaacct
    12361 ggtcctctca tgtaccaatg tgtttggtga acaacaacag acatttggct tagatctgca
    12421 actaattgat ttaatacttc tttggtttgt tggaatttca tctttcttgc ctcctaacat
    12481 tttcttacac ttaaaataat agtagacttt caatgaaaag tacaacaaaa tcatttacct
    12541 gagaacgatt ttcagttcgc ttttttatcc gtaaagccaa tcatttttca gaatcagcta
    12601 attcttctcg cagttgagca aattgctgat aagtctgtgc taaatgcttt tgtgtcgaaa
    12661 caaataatgg atagattttc tgatattttt tatgatcagt ttcttgtact ccaacttgct
    12721 ctttcaattc tatcaattcc tgtgcttcac tgatactttg gatctttccg atgcttctcc
    12781 agcctaaaat cacagctcct aatgcggatg cttctgtgac agtagggaaa acaagcgggt
    12841 aacccagtac atcagccatc atctgacgaa aaatcggaga ttgagcaaac ccgcctgtag
    12901 cacggatctc tgtgagctga ttttcctggc aaactccttt taaaatccga taaaggttga
    12961 gacagatccc ttctagaatc gccttcatca tttctttttc tgtatgttgc cgctgtaaac
    13021 cgataaaact gccaaacgca tctgcgtccc aaagcggtgc tcgctcacca agtaaatagg
    13081 gatgaaaaat cagaccattg gcacccgctg gcacaaaagc gatagccgaa agcagtgcat
    13141 catatggatt ttctcctttt tctttagcag attgaacgac ttcctgtaaa aatgtatgcc
    13201 ctgcccaatc aaagatgcca gcaccattgc tagtcgctcc tcccactacc caatgtttct
    13261 gatccagaac ataacaaaac gtctccattt ctggatggaa ctgaggctga gtagtaataa
    13321 aacgaagtgc tccgctcgtt cctacggtca aagcggcgat cgtatcacca aaagcaccta
    13381 accctagatt agaaagcggc ccgtctgccc ctcccaaaac aaatgatata tcatttggca
    13441 aacctagttc tgctgctgtt tttgatggta gacctgttac ttgataggtg gaaggaaaga
    13501 cttgcggcaa ttgctctatt cgaatgttca agtagtcaag cacttcttct gcccattgga
    13561 attcatggat atcaaaatat ccagttcctg aagctgttcc gtagtcgctg atcagttcgc
    13621 caaacaatct ataaaagata tagtctttga taccgacaaa ataagcagtt tttttgaata
    13681 attcaggttg gctgttttgc agccacttga ttttgttcaa tggtgtcatt ggatgaatcg
    13741 gcgtcccagt ctgccgataa aattctttgc caagcacggt atatttcagt ttttctgctt
    13801 cgtccgctgc tcggttatct gcccaagtga tcattcgaga taacggtgtt ttctcttcat
    13861 ccaacaatat caggccatgc atcgcagagg agaaggagac aaattgaatg attgtgtctg
    13921 aaggcaactg tttaattact tcttttataa cggtgcagac accttgaaag atcaattcct
    13981 gatcttgttc tgccatccct tgtgtttctt ggatcaaagg gtagcgaaaa taagcggatg
    14041 ctgcttcttg ggcttcatct gtgaaagcaa ctgctttggt ttgtgtggtt ccgatatcta
    14101 atccgattga aacgttcatt ttttcacctc aaattttatg tatgtacaaa aatttagttt
    14161 aagcttgcgt atcttggttt tgaaaagggg gagatggcgt gttactttat tttatcattg
    14221 gttgctgtat cggatcattt ttatgtttaa ccgcccagcg gattccgtta ggtcactcta
    14281 ttatttatcc tagatctcat tgtgtcaaat gctgtcgttc gctttcttgg tatgaattga
    14341 ttccgattct ctcgatcatc gtccaacgat ttcgctgccg ctattgcagg tgtcggttgc
    14401 ccttctacta tttgttggca gaagccttat gtggtggtct ttttgcctgg ttctttactt
    14461 tttcttccgc aagaaatttt tcgacgttca tatggatgct ttcggctttg ctattttcgt
    14521 tgatggattt attttacttc atggtccatt ctcacacgct attctgttct tgggcaattt
    14581 tatggatttt ttggttgcag gccggcgtct tccaatggca aagtgtgctg ttaacgttta
    14641 tcgtaggcgg tgtgtgcctt cgctatggtc aatcctatct cggagctggc gatactctgt
    14701 tgatgctttc ttggagtggt ggcttgtctc tagaagagtt gcttcagatc ttgtttcttg
    14761 ctagtctgtt tggaatatcc gttttttctg tttactttat ctgtcataaa aaaaagttgg
    14821 aaaagctgcc tttcattcct tttttgagca gtgcgttgct gattgtcctt catcttaggt
    14881 attgaaaaaa ggttgtgaca aacgacttgt cacaacctct gatatatagt gttctcttac
    14941 caaatccttg tgacttggag ctaggcgaca ggttcacaac ctctccacta aatggtgttc
    15001 aatcagctga ccctcagtat tagctcaaaa tgctggtttt acaacctctg atatacggtg
    15061 ttccataagt agctttttcg gcttcttatt tcttgacgcc ccaatgtcga cgaaggaaac
    15121 ctgcacgtcc agaaccttct cgataaagat tgtaatggag cttgtttttc ttgtaataat
    15181 cctgatggta atcttctgca ggataaaatt cgcttcttgg ttcgattttt gtcacgattg
    15241 gcttatcgaa tcgcccgctg tcttgcaatg cttgttttga acgctctgca atatttcgtt
    15301 cttcttcatc attatagtag atcactggac gataagaatc accgcgatca gcgaactgtc
    15361 ctaatgcgtc agtcggatcg gtttgctgcc aatagatttc caccaactga tcataagaaa
    15421 taacttctgg atcatattcg atctctactg cttctgtatg ccctgttgtg cctgttgtta
    15481 cttgttcata agttggattt ggtacatgcc cgccagtata accggatgtc acagaaatga
    15541 tccctggctg ctcttcaaat ggtttgacca tacaccaaaa gcatccgcct gcgaaaactg
    15601 ctttttttgt catataaaat cccccttttt tctcatcata ccttgatttc caaaaggagg
    15661 ataacgtttt gcttgtgaca gaaaaaacgg aaactattat atacgtgata cggcttctga
    15721 taaatgccaa aacgaacgta cttgatcaaa aacggttaaa tcaggaatca catattcagc
    15781 agaaggaaga tttatgtttt cacctattcc caatacatgc atgttaccag ccaaagctgc
    15841 ttgacaacca gcttctgaat cttcaatgac caagcatgca tttggcggta cattcaattg
    15901 ctgtgctcct ttgagaaaaa cttctggatc aggttttgct tttgatactt gcgtgccgtc
    15961 aataaggaca tcaaaataac ttgtcaaatt cgttttttct aaaatgaggc gtgcattttt
    16021 gcttgctgat cccaatccga tcttgatgtt tgtttttttc aagtactcaa gaacagctat
    16081 tgcaccaggc aaaacggatg tttcatccat tttttgaatc gcttgaagat atagattgtt
    16141 tttttgctca gcaaaggctg atttctcttt ttctgagaat ttctgttcca tttttccaaa
    16201 tgacagcaat cgctctagtg actcggttct ggatattcct ttcagttgct cgttttcttt
    16261 ctcagtgaat ggaatggaca gctggttagc taaaaccagc cacgcttcgt aatgataacg
    16321 agctgtgtct acaagaacgc catctaaatc gaatagtgct gctttgattt tcatcgatta
    16381 cctccttgaa aatgaacgac ttgaagtaaa gatgcgatgt ttttagctgt gcgatgaaga
    16441 ttatcagtgg cttgctgtaa agcttcttgt aaaggcacag ctgcaggaag gatcggaaaa
    16501 acggccgaaa tgccaacatc tgctgctttt tcgcttcctt taccaacact tccgcaaata
    16561 gctatcacag gaacgccctc tggtactctt ctagcaatcc caactggcgc ttttcctttt
    16621 agactttgtc catctagacg tccttcgcct acgattacga ggtctgcttg ctgtacccgt
    16681 atcgaactcc agtaaatcca atacgtagtc gatgccagag actattttcc ctgaagcaaa
    16741 tgctaacagt cctgcaccca ttccaccacc agcactactg cccgatgcct cgattacttg
    16801 aggggcaaat ctcatataaa aatcatgcat ggcttggtca gccactgcta attcattttc
    16861 tttcaagcct ttttgtggtc cgaaaacaaa agaagcgcct tcttttccgc ataaaagatt
    16921 agtaacatca gtaatgacag tgattttggc tttaatcagc tcaataggca cgttcgtttt
    16981 atcaactgta gcaattttac ctagattttc tcccagtgct tctacttttt gattatcttg
    17041 atcgtaaaaa gcataaccta gaccttctgc catgccgatg ccgccatcgt tggtactact
    17101 tccgccaacg ccgatgatga tgtgtcgaac accttgttgc aacaattgtc gtatcagttc
    17161 tcctactcct cgcgtggata acctaagtgg ctgttgttgg tttagtggga catctttcaa
    17221 tccgacgatt tctgccattt caaaaatcgc agtttgaccg tctgaagcgt actggatttc
    17281 tttgtttttg ccaaatgcat tagtaacgac tgctgtttgc cgcttcaacc ttaaactgtc
    17341 tgctaatgat gaaaccgttc cttctcctcc atcgcctata ggtagcagat catattcagc
    17401 ctgaacaaaa acttcttgaa aacctgattg aatggcttgt gctgcctcta aggctgtcag
    17461 actttctttg aaagaatctg gcgcaatcag aatacgcatt attttcccct ccgttccaag
    17521 atcagttctt tttccagctg gtattggtct ccattgacaa aaataggtaa tgtttctttc
    17581 gtctcttttt ttattactat ttgttttttt gtcaaaacaa atagcaacct gtgatttttc
    17641 caaataaaag gaaaagaaat tttttcccat gctgaaggaa gtcttggaga aatagaaaga
    17701 gttccattcg ttactgtaat acctgaaaaa ccaaatataa ctgctagcca tagtgctcct
    17761 aatgaagcag catgaattcc gtcatctgat gaatgcggat ctggtcctaa atcaatcagg
    17821 cacgcttctt ggaataaatg atacgcccat tccatttctt ggatacggca agcctctatg
    17881 gcgtgaatcg ctttactcaa cgatgagtcg tggattgttt tgttttcata gtaatgcaaa
    17941 ttcttagaaa cgattggttg agaaaaatac tcaggtaata agtataacag catgacaaga
    18001 tctgcttgct tgctgacttg gagttcattt acttcgctac gggcataatc aagtaaaata
    18061 gactggctgc caggacgttc tttgtaagtg gtcaaatcaa taactggctt actgagatac
    18121 gtgtcatctt gcggaatcag ctgttctttg ttaggcactg gcaaatataa cttatctaaa
    18181 aaattttgac attctttcaa aaaaagcgga tcgccagctt gatatttaac agctaaggcc
    18241 acattataat gcgccagata gttcgtatat gcattattgt cgatatattc tgtgtattca
    18301 tctggaccaa tgactctgtg tatctctaaa tgatcatcga cttttacagc tctgctcagc
    18361 caaaaagctg ctgtttcatg aatgagcgtt tttccctttg tttctaaaaa cgattgatcc
    18421 tctgttgctt ggacatactc ttgaacggca taagcaaggt ctgcactgat atgatgttct
    18481 gcggcagctg aagcaacttc ttgtcttgtt ccggttttga tattcaatgc agcaaatttg
    18541 ggtgtctctt cctgaccagt gtgtgcgctt tcccatggga aaagtgcacc ttgatagtga
    18601 taatctcttg ctttttgccg tgcgccttct aatcgatcat aacggtacag cagcaaattc
    18661 tttgctactt caggaaactg atataaaaag aaaggcagga taaaaatttc cgtatcccag
    18721 aaaacatgcc ctttataacc ttcgccagtt agtcccttcg cccctacact aacacttgga
    18781 tcattgcggg gagtcataat ctgtaaatgg taagcagcga agtccatcgc taactgatcg
    18841 aaagaagaat cgccttggat cgttatccga tgctgatgcc aaaaatctgt ccaataagac
    18901 atcgactgct ctaaaatttc tgtataacta acgcttttct gggcttgggc aatacttttc
    18961 ttaaacgggt ctgtttgctg aagagaggta gagagcacga tgatcttctc cagcgtaaag
    19021 gacgtatttt ttctgatctt ttctgaaaag gaagcggtga tccggcgatt ttttgcttgg
    19081 aatacacctg ctttattgaa tttagctgca atcccaatat caattttact ttctgttgtc
    19141 tggtaggatg cactgatcaa atcgtcacca aatactcgca gttctttttc aaccaactgc
    19201 tgtgtaccaa aattggtttg ctgtccatcg atacccgttt tcacatctac ttggcagtct
    19261 tcggtcaacg gcttgatgac cactttcagg gctgcctgat ggagattatt ttgatcagca
    19321 acacgacaag taatgacttc cacttttttt ccttgagcag tttcaatgag cgcatagcgt
    19381 ttaagctctc ccatttctaa atctagtgcc cgctcgtatg caagaacttt catcgtctca
    19441 agagaaaaat gttcaccgtc gatttttatt tcccatctga tgacatctgg gagattcact
    19501 aactcggctg attctgctcc taaaggtcgg ttatatacac cagctgcaaa cattcccctt
    19561 acttgattcc gatagtcttc ctcctggctt cctctgatac caaaaaatcc atttccaatg
    19621 gtcatctgac tcgcatactt attgatatac tctaaatcaa actgtttttc ttctactttc
    19681 ataaggtaat aacttctcct gtttctgccg aacgatataa attttccacc agattctgga
    19741 tgacatatcc ttgccagcca tctgcaatca tctgagtctg gtcaccgagc gcccgattca
    19801 caaaatgagc catacttagt tcatgtgggt cattaactgg cgtggtcttt tgtaaggaaa
    19861 ccagctttcc atctacatct tcgaatagtt cgcctggata cagattagca cctgcctgat
    19921 cgccacaaaa agccacattc agtttgtctt ctctgatatt caaagcaaac gaagtattca
    19981 gttggatgat cttgccgttt tctaattcca gtgtgccaaa aattgcatct tctactgtga
    20041 atttgcttgg atcccatttc ccgaatttcc ctgaattttt tttcgtacca attttttgga
    20101 agctgtacgc ccgaacgctt tttactttag gaaatccagt aatatacatc gctgtatcaa
    20161 gcatgtgaat gccataatcg atcaaaggcc cgcctccttg aagttctttg tcgataaacg
    20221 ttccccagcc tggaacacca gaccgacgaa gcgcattcgc ttctacgtaa taaatatccc
    20281 cgagaacatc aagatgattc ttgatcattg ttgcttcgtc agaaaaacga tgctggaatc
    20341 cataagccaa aatctgcccg tttttatcgg ctgtctctgc catctttctt gcttgatcag
    20401 ctgtcatagc tggtggtttc tcgcacatca ctgaagcatt agcttcgagg gcagccaata
    20461 catgttcgaa gtgaaagcga ttggctgtac agacactcac gatatcggga gaaatctcat
    20521 tcagcatttg tgtaactgat gtatacgcat gagaaaatcc tgtacgtcgg caaaagtctt
    20581 ctgctcgctg gctgactgga tcaaccacag cggccaattc taagacatct gatctttttt
    20641 gataataagc agcatgtact ttttctgcta cttgtccagc gcctatgatt gctactttct
    20701 tcatttattt ctctctcctt tgcttattta cttattgtta ttctttctct attctttctc
    20761 taaatcattt aaatgacgcg ctgtttccag acagtttttc aagtattgca atgattcctg
    20821 ataaattttc acttcatttt ctcctcgcaa acgacattca tataccatat aaccttcata
    20881 ctcattttga agtagcgttt gaaaatggcg agtaaaatca attgcgccag atcctggttg
    20941 gtagcgatga ttatctgcta aatggatatg acccacatac tctttttgcg tagtcaatgc
    21001 ttttgaaata tcatcttctt caatattcat atgataaaaa tcagcgatga tctgcacatg
    21061 tttcaattga ttagagtcaa tgtaatgacg cgcatccgct aacaaattga tcatatggtc
    21121 ttggtatcgg ttcaaaggct ccaaataaat aaccgtacct gtttcttcgg ctactttatc
    21181 taaataacga agtgattcgc tgactgcttt atagtctcct tctttgcttc ggggtgaaac
    21241 catcggcggt aatcgataag tgaacattcc ccaagctgct gggataacga ttcctttgcc
    21301 tccaacctcg cttagtgcac gcaaaatctc agcaatttga cgtacaccat taagacgccg
    21361 ttcttcgata aagtcaccga tccacccatc gtagccgtta caagctgtca ctactgggat
    21421 ccctgtttct ttgattgcct gtttgactgt gtcgatattt tctattaaca acttaccgtc
    21481 gatttcgtat tcttcaaatc cacagtcttt gataaatcta aatttttcta aaatgtctct
    21541 tgggaaaaat gcttgatctt gcgtaccgaa tttcattgtt ctcctcctcg gacttgaacg
    21601 cccattttga tactttcttc tgggtgctgg tctacataac gcatgtaagc ttctgcgctt
    21661 tctgcaaatg gcacaactgg atcaatgatt tcttcacaat ccaagtaacc gttcatcaat
    21721 aattcccaac atgtgtcctc gattcgttta cggttccatc ttgggtaatc tgggtttggt
    21781 tcactagatg ctcgagcaaa gacgattttt gcattattga aatgtgcttc gcgaccaaga
    21841 ttaaacccag ctggaaaagg tttagcaaag gcaacataag aaatgatccc gccatagccg
    21901 atccctctta aagaagcttg taatgcggca gcactgccac tcgtttcaat aactgaatct
    21961 actccacgtt tatctgtcaa ttcctttaga cgaaaaccga catctgcttt cataggatct
    22021 agcgtgtaat cggcaccgta tttttctgct aattctctac gctgcgctat gggatcgatc
    22081 ccaacgatgg tagtagcacc tgctttttta gctaattgaa tcgcaatttg cccgatagcg
    22141 cctaaaccga agattgctac agcatcacct gctcgaacat gtgcttcccg gataccacct
    22201 aaagcgaatt gagcaggatc gtaacatact gcatttttcc attgatccaa ccgatcaagt
    22261 ttacgtagtt tataattatc aacaccgttt gtaatcagcg tttcacgaat gggtccataa
    22321 gtgcagacta actctccttt ttgatactct gtcaccaaac tgcccgtttc ttcgatcgta
    22381 ccgacaatca tatttcctaa ttgaaattcg ccaaatacca caccgcgttg gcttccttct
    22441 tctcttggca agaataggcg ccattcttct gaaaattctt catcgataaa tggacttaat
    22501 cctctaaagt cgacaatttc tgttcctggt tttggagtag cgaaaattac tcggatacgt
    22561 acttcgttct tttcgatctc acggtcttcg taatctttga atccggctat tcttggttct
    22621 aatgcaacta attttttcat cttttctttc ctctttcttt tctttttatc cttttacgcc
    22681 gccttcgact aaatcacctt taataaatcg ttcagataac gcatacataa tgatgactgg
    22741 taaagcggtc accaatgaag cggccatcat tcgtccccaa atgtagtctg gtgtactgaa
    22801 taatgtgttc aaaccgattg gtaaagtaaa tttttcggag gtcgacagga aaatcgaagc
    22861 aaataaataa tcattccacg aaaccataaa gcaataaacg aagacagaaa tgattccaga
    22921 aatagccaat ggtataatga tccgaataat gatctggatc cggctaagac catcgatcat
    22981 tgctgcttct tcaatatcag tcggaatcgt gtcaaaataa ctttttagca tgaatatcgc
    23041 agtaggaagt gtttgaacga ccatcgtgat aatcagtgct gtattggtat catacaaacc
    23101 tagaccggaa atgattttaa ataatggaac aacgatcaaa ataccggaaa acatataaac
    23161 ggtgtaaaag ctagcattga ttttcgagcg agctttgaag cgtagttttg acaaagcgta
    23221 tgccccgctg atcccaatca ctactgcagt tacggaggct atcaaggaga tcactaaact
    23281 atttttgaaa tacatgatga atggaaaaat ctcagcattg aaaatatcct gataatgttc
    23341 aaaagtccat tctttcggaa aaatagtttg tgtcgttgca attgcttctt gtgaatcctt
    23401 gaatgatgtc atcagcatga tcaaaaatgg aaacaaattg acagctaata gcaacaaaat
    23461 cgtcgcgtaa aataagattt tcctgctctt tttatttttc atttcaagtc caccttcttt
    23521 cgtgagagca agacgaccgc tgcaataatg atgaacaata gaatcgatat agctgctgct
    23581 tttccaagat cattgaacgc aaaggctgtc tgatacaaat aaacgcctaa gatattgact
    23641 ttattcgtca gtagatagac atctgtaaac atatagaaca tccagataga tcgtaaaaca
    23701 atcacagttg ctagtactgg tttgattgcc ggcagtgtca cgatcttgaa cttctgccaa
    23761 gcatttgcac cgtccatttc agctgcttca taaagcgttt tgtcgactgt ttgcaaaata
    23821 gccaaaaatg aaataaacgc atacggatag tatctccaga tagcaaacaa aacgaccata
    23881 aagaagctag caactggctg gtcgaaccac agcggtgctt cgttgaaaag ctgcaaccta
    23941 tctactaaca gatcattgac gattccataa ctattattga acatatattt ccaagcaaaa
    24001 atcaaagaaa tagatggcgt aacataactt aataaaatca gtgaacgcac cgttttccta
    24061 aatctgaact tgcggttaag caaaatagct acggctaatc ctaaagctgt actgcctgct
    24121 acaactaaga atgtgtaagc aactgttaaa cctaaagaac gataaaattc actatcactt
    24181 aaaatttcaa gataattgct taatccgata aaaacggcgt ctgagttagg attcagcggc
    24241 atatcgaaaa aactgatctg aatattggaa agcattggaa tcagcactaa aacagctaat
    24301 aaaagcatgc ttggtgctaa aagtcccatg gctaatttta agtcagaatg tttccttgga
    24361 cgattcattg aaacctcccc ctgataatct gccaatagct atctactttt ttcgaacacc
    24421 attggcagaa cttcttgtta tttcgtattt ttttgtgcgt cagctaaagc ttgatcgaca
    24481 tcttcgtttc cgacagttac ttggttcact gcttttccga tcacacctga gcttgtgata
    24541 tctcccattt tcgtgaaatt cttttccccg actagtccaa agacttgtac ttcatcaaaa
    24601 gcactagcaa tctcagatgg cagctcgcca aaagacttga tgacttcatt ttctttgtaa
    24661 ccatccagtt cgactacttg tttattcact ggttgagcac caccaggaga catcaagacc
    24721 cacttttcca tgtttttcgg ttgagataag aaagctgtga atgcttcagc agcctctttt
    24781 tgtttctcgt ctagaccaga agaaatcgtc aatccagata ctgtgccata gacagcttga
    24841 tctttttgtg ttgggatagc aaaaccgata ttttctgagt tccccgcttc ataaacagaa
    24901 ggcaaaatgt aagttgaata gattgccatt ggtgctgttc cattcatgaa agcatctttg
    24961 atttctgtca catcattaga gcctggcatc gtgtattggg ataagttttg ataaaacgac
    25021 aatgcttctc tcatcttttc cgtatcgatc gttacctcgc cttcatcatc caaaacattt
    25081 gctccatttg acaaagcaaa ttgagagaac gcttgctcac tcattgttcc ttcagcagta
    25141 ggcatagcaa ttccatattg tttattctct ttatctgtga aatgttgagc aatttttaaa
    25201 atatcatccc aattttctgg ttctgaaaaa ccagcttctg ataatttttc tttgtcatac
    25261 caaatacctt gaacccagcc gctaattggt gcagcaatat agctttttcc atcttctgaa
    25321 cgaacaaggt ttttggctcc gtcataataa ttatcttctc cagcttcctc gataacgttt
    25381 tggactgccg tctgatcaat cagttcatct ttatccatca ctttagcaaa atcctgactg
    25441 acttccatta cttctggtaa tttaccggaa cgagctaacg taacgatttt tgtattgaac
    25501 gctgattctt ctaccggcac ttgcttgatt ttgatgtctg gattttcttt ttcaaaatca
    25561 gcaaccagtt cattgatcac acttaatcgt tcctgttcga cagaagagtg catgaattga
    25621 atcgttgtct gttgtgattc gttagagctt tgactttcac cacaagcagt aagaagaaat
    25681 ccagtagcta gcagacaggt agtaacaata atttttttca tttttttcca cctcttattt
    25741 tattattttc agccacatat attcatacgg ctggaatatc aactttcgtt cttgactgca
    25801 atggataatt tgtccagaaa acaggtctag gtaatctcct tttggtaaaa gataacctgc
    25861 tgattgattg gaaaaattat ggataactaa gactttctct tccttcgctt cgcgaataaa
    25921 actgataaaa gaatctgctg agtccagtaa gtaaatcaaa ctattcggat ggaaggcttt
    25981 ttcttttttt cgaatagata gcatctgggt caattcacca tatactgctg ttcttaatgg
    26041 atctgtctgc aactctttct caatatctgc taacaaaaat ttttgccgat tgatttttcg
    26101 attctctcct gttttttcta cgcctttgta atcatttcga cttcccagca cactttgaat
    26161 ataaattgcc ggcacgcctg gtaacgttac caaaaatgaa tgagcagcta aaaagcgttt
    26221 gcttctccat tccgtcgtat ctgttggaga acttaacgca tctagatacg tagcgtttat
    26281 ctcatatgga ctggtcgttc catctgggtt tttcttgtag tttactcggg caccctcttt
    26341 cttcagctgt tccactaatt caaggatcgt tttttccggc agaatacctc gtaccggatt
    26401 caatccgata ccgtcatggg aggctaaaaa attaaaaaaa gttgtttttt tcgatgcgaa
    26461 atcgatggtt tttaaccatt ctttcaactt acttgtatta cccgaacgaa tcgcttgaag
    26521 ggtcaaaggt ggtagcgaaa actgatagac catctgtgct tcattctcgc cattcccaaa
    26581 ataactgata ttatctttgt gtggcacatt tgtctcagtg atcaataccg ttcctggagc
    26641 tgcttcatca gcgattgcac ggaataattg gatgatttta tgcgtttctg gcaggtgtat
    26701 acaagaagtt cctagttctt tccataaaaa tcccacagcg tccaagcgaa taaatgaagc
    26761 gcctttttct aagtaaaaca aaagaatatc gatcattttc aataaaactt ctggattttt
    26821 aaaattcaag tctacttgat cttcgctaaa agtcgtccat acgtgttttt ctttcccgtt
    26881 tttgtcaatg aacgttgtaa gtaacgggct ggtccttggt ctagtcacgc tgcttgtatc
    26941 tgtatccagt ggcaaatcaa taaaaaaatc tttgtacgta tcattcaagt ttaaatattc
    27001 ctgaaaccaa gtactttcgg cagacatatg attgcagaca aagtcgaaca ttaaccgtgt
    27061 ttcgcttctc atttcttcta tatcttccca tgtgcccaaa cggtcgttga ttgcctgata
    27121 atttacaacg gagaaaccat catcagatgt atatgggaaa aatggcaaga aatgtacaac
    27181 tctaaatgta tctgccaaat acttttgata aaatttctta aatgtacgca aagttggttg
    27241 ctgctcttca aaaaattgat ccccataagt aatcaagaaa atatcttctt cgtcccaatg
    27301 cagtttgcct gcctggcctt tcttctgctg ataaacactg actttttgtt caatcataga
    27361 ggcggttttc tcagacaaat ctgagtcgcg ataaatcgct tgtaaaagtt ttgtatacat
    27421 cggattcccc tttctttttt gggagcgttc ccaacgattt gatcatatta tggaaaacgc
    27481 ttactgtcaa tagcattttt ttaaataatt ttgatataca caaaaataca aataagaaag
    27541 cttatgtatc aataattaat agcttcttaa aaaaatatgg tctctcatga tcatgcaagc
    27601 tattcctaaa ttttcaaaat catagacaaa aaagaatgtc tattgtacta tggaattatt
    27661 ctaaaacgct cccaaaaagg aggtgcatat aaaattgaaa cctactattt atgacattgc
    27721 gaaaaaagct aatgtctcaa aatcaactgt ctccagagta ttaaataacc agccaaatat
    27781 ctctgataaa gcaaaagcaa gtgtacttca agcaatcaaa gaattgaatt atgaaccgag
    27841 caaaattgca agaggactgt caggaaatgg ttttgacgcg attctagcat tatctcatcg
    27901 tacttctcat acgacctatg gcaatccttt tttttcagat gttattcaat ccatttctgc
    27961 cgtttctgaa caaaataact tcgacttgat tctacaaacg gcaaaaacac cagaagaaga
    28021 gctagaaaaa tgcgcgaaaa agatccaaga aaaaatgatc cgaggaatta ttattttaag
    28081 ctctacgatg gatgaaacac ttctttttga attggatcaa tacaatattc ctattgtggt
    28141 aatcggaaaa gtcggaaacg actacacgaa catctactca gtggacacgg ataatttcca
    28201 ggatagttac gatttggtgg aaacactgat caagaatgga caccgtcata tcggctgtct
    28261 ccatgctccg acagaagttt atgtatccaa tgatcgtctc aatggttacc gtcaatgctt
    28321 atttgatcac cacctagata tccgtaatga atggattata gacggcggct ttcgcttaga
    28381 agatagcatg gcagcaatga atgatttaat gaagctacga gaaagaccaa ctgcgatttt
    28441 ttctaccgat gcattaaaat cattgagtat ttacaaagtg gcagaacaat ctggaaagca
    28501 gatacctgat gatctttcga tcgcaggatt cagtgatccc ttattgtcct ccctattttc
    28561 gccacagttg actcggatag acattccgac aaatcagtta ggaatcaaag ccacagaact
    28621 tttattccaa ctaatccacc accaataccc tgaagaaaaa agaatcattc tttcaaccga
    28681 gattactctc acagattcga tccaacaaca agaaatgtag aacagaatta taaaagaaca
    28741 gaaacactga ggataagtca gttactctgt tcttttttca atcactcatc cctcgttacc
    28801 ccctcccggt attttagcga atttttctta ttttccatct gttttagata gctgtggata
    28861 actataatgt ttgtgttaaa ctattttttc cacagggaag aaaaaactat ttttaaccac
    28921 gttgtgtata agtttttata gttcgttttt ttaaacacat ttacccttat ttcaatccat
    28981 gttatttggg gatacttatc tctaaaacat aaatagaata acagacatgt ctactggttt
    29041 tgttttattc gaggaattat tcaataatag ctagcaaaat attaaaaata accgctctat
    29101 cttcccatca atttattttg cattcaaaaa atgatctatc tttacttttg ttgattgact
    29161 tctcttggaa gatgatcgtt ccgatacctt aattggatac gaaccgatgt tgttaagatc
    29221 ctttcccact tttcttctag ttagacaaat tattttagac aaaccaaaaa agaggttgtg
    29281 acaataattt gtcacaacct cttttttaaa atatctattt tgtttgattg ttcattgcgt
    29341 cttctgcagc catttgcgct tcaatatctg aaatactgta gacattttcg cttgctacac
    29401 cgacttcttt tggttccatg tcacgataac gttgcatacc agtaccagct gggatgatct
    29461 tacctataat aacattttct ttcaaaccaa gaagaggatc tttcttaccg cggatcgcag
    29521 catccgtcaa gacacgagtt gtttcttgga atgatgcagc agataagaaa ctatttgttt
    29581 ctaatgatgc ttttgtgata cctagtaaga caggtcgaga agttgcagga acgcctcctg
    29641 agactagcgt attgtagttt tgatctttaa agtctgcgat gtctaataat gtacctggta
    29701 agatatctgt atcacctgga tccattacac gaactttacg cagcatttga cgaaccatta
    29761 cttcgatatg cttgtcgccg atttctaccc cttgcatacg gtaaacacgt tgtacttcac
    29821 gaagcaagta gttttcaaca gataatacat cgcgaacttg caacaattgt tttggatcga
    29881 ttgatccttc tgtcaatggt gcaccacggt ggatcatatc gccttctgct actttcatac
    29941 gtgctgtata aggaacagta tacgtacgtg tatctgtttt tcctttgatt gttacttctt
    30001 tggtacgtgt tgcaggatct tctgagatat cgatgacatc ccctgttact tctgtgatca
    30061 ctgcttgccc tttcggatta cgtgcttcaa agatttcttg gacacgagga agaccttgag
    30121 tgatatcgtc tccggcaacc ccacctgtat ggaatgtacg catcgtcaac tgagtaccag
    30181 gttcaccgat tgattgagcg gcgatcgtac caactgcttc tccgacttca acgtcagagc
    30241 cagttgcaag gttgcgtccg taacaatgtt tgcagacacc atgttttgta ttacatgtga
    30301 agacagaacg gattgtcact gtttcgacac ctgcatcaac gatttgtttt gcgatgtctt
    30361 cggaaatcaa ttggtttcct gcaatgatca attcatttgt ttcaggatga cgtacttctt
    30421 tacgggtgta acgtcccact aaacgatctt ctaatgattc gatgatttca tttccctcgc
    30481 ggatggcttg gatttcaaga cctcggtcag taccgcaatc ttcttcacgg atgattacat
    30541 cttgggccac gtcaaccaga cgacgagtca agtaacctga atcggcagtc ttcaaggctg
    30601 tatcggtcat ccctttacga gccccgtgag ttgagataaa catttccaag acggatagtc
    30661 cttcacggaa gttcgaaatg attggcaatt ccatgattcg accattagga gcggccatca
    30721 aaccacgcat tccggcaagc tgtgtaaagt tggaaatgtt accacgagct ccagaatcag
    30781 acatcatgaa gattggattt ttcgcttcca aaccttccat cagtttttgt tggatgctgt
    30841 cttttgcagc attccaaaca gcaatgacac gttcataacg ttcgtcatct gtgatcagac
    30901 cacgacggaa ttgttttgta atagtttcaa cttgtttatg ggcattttca atgatttctt
    30961 gtttttcatt cagtacactg atgtcagcga tccctactgt gataccggca tgtgtcgaat
    31021 gtttgtaccc taagtctttc atacggtcaa gcatcttaga agtttctttt actttgaatc
    31081 gtttgaagac ttctgcgatg atgtttccta agtttttctt cttgaacggt aatactaatt
    31141 cttgctcttt gatatgtgca ggaatatcag taccagcttc aacaaagtat ttgtccggtg
    31201 tttggacggt caagttgaag tctgttggtt cattcagata agggaattca ggaggcatga
    31261 tctcgttgaa gatgatctta ccaactgttg tgatcatcgt acgttctttt tgccattcag
    31321 taaatggttt ttcacctaat gagttagggt tcacaccgat acgtgaatgt aaatgaacat
    31381 atccgttgcg ccatgcgata acggcttcgt tttgatctct gaagaccatt ccttcgcctt
    31441 cgcgtccttc ttcttccatt gtcaagtagt agttacctag aaccatatct tgagaaggag
    31501 taacaactgg tttaccatct ttagggttca agatgttttg agcagctaac atcaacatac
    31561 gtgcttctgc ttgtgcttct tcattcaatg gaacgtggac agccatttgg tctccatcga
    31621 aatcggcatt ataagcttca catacaagtg gatgcaaacg gattgcgcgt ccttgtacta
    31681 aaactggttc gaatgcttgg ataccaagtc ggtgaagcgt aggtgcccgg ttcagcaata
    31741 ctgggtgttc cttgattacg tcttctaaaa catcccatac ttcgtcttct tgacgttcga
    31801 ttttacgttt cgcatttttg atgtttgaag ctagttcgcg ttgaacaagc tcacgcatca
    31861 cgaatggttt gaataattca atggccattt cttttggaag tccacattgg tacatcttca
    31921 agaaaggtcc aacaacgata acggaacgac ctgagtagtc gacacgttta cctagcaagt
    31981 tttgacggaa acgaccttgt ttccctttca acatatgaga aagagatttc aatgggcggt
    32041 tacctggtcc agtaactgga cgtccgcgac gaccgttatc gatcaatgca tctactgctt
    32101 cttgcagcat acgtttttca ttttgaacga tgattccagg tgcattcaag tctaacaaac
    32161 gtttcaaacg gttattacgg ttgattacac gacggtaaag atcattcaag tcacttgttg
    32221 caaaacgtcc accttctaat tgaaccattg ggcgtaaatc tggtggaata acagggataa
    32281 cgtccataac catccagctt ggttgatttc ctgaagcgcg gaatgcttct aaaatatcca
    32341 aacggcggat tgcacgtgta cgtttttgtc cttgtgcaga tttcaattct tctttcaatt
    32401 cggctgcttc tgcatctaga tcaacattat caagtaattg tttaatcgct tctgcaccca
    32461 tagcagcttg gaattcttgt ccatattgtt cacgtttttc gcgatattcg cgttctgtca
    32521 acaattgttt tttctctaaa ttcgtatttc ctggttcgat gactacatat gaagcaaaat
    32581 aaatgatttc ttccaaagcg cgtgggctca tgtctaatac aagacccata cgtgaaggaa
    32641 tccctttaaa gtaccagata tgtgaaacag gagctgctaa ttcaatatgt cccatgcgtt
    32701 cacggcgaac tttcgaacga gtaacttcca ctccgcatcg atcacaaacg attcctttat
    32761 aacggatacg tttgtatttt ccgcaggcac attcccagtc ttttgtagga ccaaaaatcc
    32821 gctcacagaa caacccttcg cgttcaggtt ttaaggtacg atagttaatc gtctcaggtt
    32881 tttttacttc accgtaagac cagcttctga ttttttcggg agaagccaaa cctatttgca
    32941 tactttcgaa tttatttaca tcgatcaaaa ggggttccct ccatttcatt taatggcaaa
    33001 ccgcaagacg gctgatcttc gaccgccttg cagctcatag accggattag tctaaattat
    33061 cttctgcggt ttcaaagttt tggatgacat cgtctttttc atcttccact tgttcagcag
    33121 ctttcttttc taattctttg gcagtttgct gttcggcaaa ttttgtcaaa gcatcaacag
    33181 tgatcaaatc gtcgtcttca tcgtccatgt cgcgaagttc gatctctgtt tcttcgatat
    33241 ccaagacacg catgtccaga cctagtgatt gcaattcttt caccaatacg cggaatgatt
    33301 ccggtacacc tggttttgga attggttcac ccttgacgat tgcttcgtat gttttcacac
    33361 gtccgactac gtcatctgat ttgtatgtca agatttcttg taaagtataa gccgcaccgt
    33421 aagcttccag tgcccatact tccatttcac caaaacgttg tccaccaaat tgagctttac
    33481 ctcccaatgg ttgttgtgta accaatgagt aaggtccgat tgaacgtgca tgcaatttgt
    33541 catcgaccat gtgagcaagt ttgatcatgt acatcacacc gacagacaca cgtccatcaa
    33601 atggttcacc tgtacgtccg tcgtacagaa cagttttcgc atcgctggcc ataccggctt
    33661 cacgaactgt ttcccatacg tcttcatcac ttgcaccatc aaatactggc gttgctacgt
    33721 ggatacctaa ctgacgtgca gccataccca agtgtaattc caatacttgc ccgatgttca
    33781 tacgtgaagg cacccctaaa ggattcagca tgatatcgat tggtgttcca tcaggtagga
    33841 atggcatatc ttcttccggc ataatacggg atacaacccc tttatttccg tgacgaccgg
    33901 ccattttatc cccttcatgg attttacgtt tttgaacgat ataaacacga actaacatgt
    33961 ttacgcctgg tgacaattca tctccagctt cacgagtaaa gattttcaca tcgtgaacga
    34021 taccgccgcc gccatgtggt acacgtaatg atgtatcgcg gacttcacga gctttttcgc
    34081 caaagatcgc atgcaataga cgttcttctg cagataattc tgttacccct tttggcgtga
    34141 ctttccctac aagcaaatcg ccatcttgga cttctgcacc aatacggatg atacccattt
    34201 cgtctaaatc ttttaatgcg tcttccccga cattagggat ttcgcgtgtg atttcttcag
    34261 gtcctaattt tgtatcgcgg gcttctgatt catattcttc aatatggata gaagtgtata
    34321 cgtcatcttt taccaaacga cggctcatga tgatcgcatc ttcatagttg tacccttccc
    34381 aagtcatgaa accaactaaa acgttttggc ctagagccat ttcgccttgt tccatagatg
    34441 gtccgtctgc cagagtatcc cctttttcga ctttctcacc caaatgaacg attggacgtt
    34501 ggttgtagct tgttccggag tttgaacgac ggaattttgt tacatcgtat ttatctaatg
    34561 caccgttgtc gcggcgtacg cggatttcag aagcatcaac gtattcaacg acaccatcat
    34621 gtttacataa caaagcagct cctgagtcat gcgctgattt gtattccata ccagtaccaa
    34681 cccatggtgc ttgaggattg atcaacggca ctgcttgacg ctgcatgttg gcacccatca
    34741 aggcacggtt ggagtcatcg ttttccaaga aaggaataca tgctgtcgca acggcaacta
    34801 cttgtttagg tgatacgtcc atgtagtcta ctttatcaat agatacttct aagttttcac
    34861 tttgagcacg agccataaca acgtcttgag caaatgttcc atcttcattc aatgggctgt
    34921 ttgcttgggc tacgatgtaa tggtcttcga tatcagctgt caagtagtcg atttggtcag
    34981 taacacgacc tgtttcacgg tctacacgac gataaggtgt ttcgataaat ccgaatttat
    35041 ttactttcgc ataactggac aaactattga tcaacccgat gtttgggcct tcaggagttt
    35101 cgatcggaca catacggcca tagtgggagt agtgaacgtc acgaacttca taaccggcgc
    35161 ggtcacgagt caatccgcca ggtcctaagg cgaaaagacg acgtttgtgt gtcaattcgc
    35221 caagagggtt tgtttgatcc atgaactgtg acaactgaga agaaccaaag aattctttga
    35281 tacttgccac aactggacgg atattgatca attgttgagg tgtcaatgtt tcagtatctt
    35341 ggatcgacat tctttcacga accacacgtt ccatacgtgc tagcccgata cggaattggt
    35401 tttgtaaaag ttcaccgact gaacggatac gacgatttcc taagtggtcg atatcatcga
    35461 cattgccgat accttccatc aagttcaaga aatagctcat tgaagcaatg atgtcggctg
    35521 gacgaaccgt ttttacagct gcttctggat agccgtttcc gatcacgttt acttcacgtt
    35581 cagggtctct tggtgaaaat actttgatga cttggacagt cattggatct gtgaccacac
    35641 cgtcttctga tggatagtaa gtcactgaat ttaggccatt atcaatgaaa ggagctagtg
    35701 tttccatgac ttggtgagtc agaactgttc ctttttcaac gatgatctcg cctgtttctg
    35761 gatcaactaa tgtttcagct aatgtcagat tcaatagacg tgttttcaaa tctaattttt
    35821 tgtttacttt gtaacgacca acgtttgcta agtcgtaacg ttttggatcg aagaaacgag
    35881 cattcagcaa gttacgtgag ctgtctgctg tttttggttc gcctggacgc aaacgttcgt
    35941 aaacgtcttt caaaccttct tctgttcttg agtcgcttgc gtttttatgc aagtcttttt
    36001 cgactgtatt gcgtaatgtt tcgctgtcgc cgaagatttc aaagatcgta tcatcggaac
    36061 caaatcctaa cgcacgaact aatacggtta aaggaatctt acgtgtacgg tcgatacgta
    36121 cataagagat gtcttttgca tcagtttcca tttctagcca agctccacgg ttagggataa
    36181 cagtagaacc gaatccttct tttccgtttt tgtcgacttt tccatggaaa tagacacctg
    36241 gtgaacggac taactgagaa acgattactc gctctgcccc gttgatgatg aatgttcctt
    36301 gttctgtcat taatgggaaa tcaccgaaga atacttcttg tgctttgatt tcgccagtct
    36361 cgcggtttgt caaacgcaat gttacatgta atggtgcaga gtagtttgca tcatgcgcac
    36421 gagcttctgc tactgtatac tttggttctt tcaattcata atctacaaat tccaaagata
    36481 gattgccatt gaagtcatcg attggcaaaa tgtcttcaaa catttctcta agtccctcat
    36541 ctaagaacca ttggtaagag tctgtttgaa tttcgatcaa atttggtaat tccaacactt
    36601 cactgattct tgcgaaactt ctacgttcgc gatgttttcc gtattttact acgtgtccag
    36661 ccaagctctt cacccctcta aaatgtcatt caaaaagact acccgatcaa ttgttacaat
    36721 aatatttcaa atattatttt taggtaacaa cagacatttt ttgcggcttt taggcaaaaa
    36781 aaaaccaaaa atagaacatt ctcttgaaac cttacttcgt gagcttctac ttttgtttcc
    36841 ttatattaaa gccgaaacgg acaatatttc gtttctgcct tttcttcatc agatagtttt
    36901 tgcaacttca tatactacac ttattttcta taaaagtcaa cacttcctgg cgtttcttct
    36961 gctttttcgc aacattttct taatgttttc aattttatgt tttcaattat ctgacaattc
    37021 ttaattgaca gaccttttta tctcggttat actttagaaa attcattttg tggaggaact
    37081 tctatgcgaa ccaacatcaa ccaaatcgca ccaacacaac tgaataactt ttactttagc
    37141 tactttagat aggtttgtat tcatcatgat ggatacaaac gttaaacgac agtttgtatc
    37201 tatgatggct aaagaacttt gtattgcagc aaaaagccac gtagacaaaa tgctaagtgg
    37261 ctgagcagtg aaaatacaaa gtaaaagtat caagcattct actttttcaa tttattttcc
    37321 gacttttcaa tccatttgga cattttgtct gaatggattt tttgtttccc aaaattaagg
    37381 aggaaaaaga aatgaaaaaa aatataatca tcggattagg cgctgccctg ctactagctt
    37441 taggaggttg cgcacaaaaa gacaattccg cagaggcatc agatggacaa aaaacaattg
    37501 gcgtattgca acttgtacaa cataactcgt tagatgctgc ctataaagga ttcaaagaag
    37561 gattagcaga agaagggtat aaagaaggcg ataatctaac aatcgattat caaaatgccc
    37621 aaaacaatca agacaacctg aaaagtatga gtgagaaact cgtcaaagaa gatcctgatt
    37681 tgctacttgg aatcgccact ccagcagcac aatctttatt aaatgaaaca accactatcc
    37741 cgatgactgt cacagcggtc acagacttgg aacaagccca tttagtcaca tccaatgaaa
    37801 aacctggcgg caatgtgact ggcacgacag atatggtgcc aatcgaaaaa caaatcggct
    37861 tactgttaaa tatcgtgcca gacgccaaaa caatcggcat catgtataac aacggtgaag
    37921 caaactctaa gatccaagct gatttggcag aaaaagaatt gaaaaaagcg ggcgtcaaag
    37981 tcaaagtact gacagcaaat tccacaaatg atgtccaaca agtgacgaaa agtctagcta
    38041 aagatgtaga tggaatctat attcctactg ataacacgtt cgcaagtgcg gcaagtgttg
    38101 tcggtgaagt cgcaaaagaa acaaaaacac ctgtcgttgc tggcgcagtt gatcaagtca
    38161 aagacggcgg tctagcaaca gtaggaatcg actacgaaag cttgggcaaa caaacaggga
    38221 tcatggcagc aaaaatctta gacggcaaga atccaagtga acttcctgtc gaaacagcga
    38281 atgatttgga actgtatgtc aataaagaca tggccaaagc attaggcatc aatccagaca
    38341 gcatcaaaga agctgaataa aacacaggag gattctcatg acaaatttgc tctctctttt
    38401 cttatcatct gcatcgcaag gggtcttatg ggccctactt gcgattggtg tatacgtcac
    38461 tttccgtatc ttggacattg ccgacttgac tgctgaagga agctttcctt taggtgcagg
    38521 gatcgcggca gtaagtatta caaatggcta tcatccattg acagcttgtc ttctaggctt
    38581 tttagggagt gcggcagcag ggcttgtttc cggactgctt cacacaaaat tgaaaattcc
    38641 cgcccttctt gcagggatca tcaccatgac tggtttatat tctgtcacat cccgtgtgat
    38701 gggtgcgccg aacatctctt tattgggtca gccaacgatc tttcattggg tcgagtcatt
    38761 cggcataaca aaagacaacg ctgtactgat cgtcggtctg ctttttgctt tgatcgttgt
    38821 atgtttactt gttttgttct tacgtacaga aacaggactt gctattcgtg caactggcga
    38881 taatctggca atgagcgaag caaacgggat caacacagat aatatgaaga tcatcggtta
    38941 tatgatttct aatggatgca ttgctctttc tggctccttg cttgcgcaaa acaacggctt
    39001 tgctgattta aattctggta ttggaacgat cgtaattgga cttgcttcta ttatcatcgc
    39061 agaagttttg ttacgtaacc agccactatt tctccgtctc ttgactgtcg ttttaggtgc
    39121 ggtcatttat cgttttattt tagcgttagt cttcgaactg aatgttgaac caagtgattc
    39181 gaaacttgct tctgctttcg tgctagtgat ctgtctttct ttcccgcaga tccagcaaaa
    39241 attccattta cctcaaaaaa agaaaggcgg tagtgtcaaa tgaatgacgt cttaacattg
    39301 gaaaatctcc atcatacctt tgaaaaagga acgatcaacg aaaatcatgt cctgaaaggc
    39361 attaatcttt ccttagatcc cggcgacttc gtgacgatca tcggtggaaa tggggctggt
    39421 aaatctactt tgctgaacag catcgccggt acattttctg tcgatcaggg tcaaatttta
    39481 ttgaatggaa aaaatatcac gaaaaaatct gttgtcgaac gttcgaaatc catcagtcgc
    39541 gtattccaag atcctaaact agggacagcc gttcgtttaa cggtagaaga aaatcttgct
    39601 cttgctatga aacgaggaaa aaaacgcggc ttcttccgtg gtgtcaaacc acaagaccga
    39661 acatttttca aagaccagct ggttcggcta aatttggggt tggaaaatcg tttatcctca
    39721 gaaatcggtt tgctgtctgg aggacaacgt caagctatta cgttattgat ggccacatta
    39781 cagcgtccag aactgatctt attagatgaa cacactgcag cgcttgaccc tgctacttcc
    39841 aaaacggtga tggaattgac agaaaagctg atcactgagc agaatctcac tgcttttatg
    39901 gtcactcatg acatggaaga cgcgatccgc tatgggagtc gactgatcat gctgcatcaa
    39961 ggaaggatcg tcgtagatat ccagcaagag gaaaaacagc agctcacagt gccccaatta
    40021 ttagcgttgt tcaaacaaaa cagcggcacg gcattaaaag acgatcaagt acttttatct
    40081 tcataatcag aaagaggatg ggacaaaaaa tgaacgccca ccctcttctt ttttctcttt
    40141 ccttctttcg tttttgcttt atgtatcaac cgttgtttct tcgaaaacta ttttgttctc
    40201 tccttcttcc tgatagaatg gatgggaaag gagcttgatg ccatgacaac gaaagacaag
    40261 gtacttcaat tattgaaaaa gacaccagat tttctttccg gagaaaagtt ggcacagcaa
    40321 ctggaagttt cccggacaag tatttggaaa gccatcaaag aattggaaaa ggcaggctat
    40381 cgttttgagc acgggcctac agggtatcgt tacctgccct ctgacgtact agatgcaaaa
    40441 gaaatccagc aagagctacg gtcgtttatt cctgatttga aagtacaaac gatgatgact
    40501 tctgaatcta cgatgaaaga tgccaaactg gcagcagctc aaggagattc tgtttcgaag
    40561 ttatttgttg ctgatacaca agaacaagct cgtggacgtt ttggacggcc ttttttcgct
    40621 gaacctggac gaggaatcta catgagtctc ttgctccatc cagacaaacg gtttgatgaa
    40681 ttgcctcaat atacgatcat cgcagccagt gcctgtgtga aagccattga atctgtaacc
    40741 ggtcgttctg cttcgatcaa atgggtcaat gatatctaca tggatggaaa aaaagtctgt
    40801 gggattttat ctgaagcagt cagtgatatg gaaagcggca ggatcagtca tatcatcatt
    40861 gggatcgggc ttaatttttc tgttcctcaa aatcattttc cagctgatct ccaagaaaaa
    40921 gccatctctg tctttcccga cggacaagct agtgtcacaa ggaatcagct aatcagcaaa
    40981 atctggcaag aattgttcac ttatctttct cacccagaaa aagcgttgga cttctataaa
    41041 gaaaaatcat tcgtattggg aaaaaccgtg tcgttcaatc aaaaaggaac gacttatgtc
    41101 ggtcttgcaa aagaaatcgg tgatcatggc gaactgatcg tccaaacaaa tgaacagaag
    41161 atgagtttgt cttctggcga aatcagtctc acatctatcc gtacgcaata attatcagat
    41221 ttcacaaaag gacacctgat ctcatacagt gtcctttttt ctgaattctc ttcaaaagac
    41281 tctccttatt ctatcagctg acagtttctc tatcctctag aaaaaggtat tctaaaaata
    41341 tctataaagc atggtacact ttctttaaat gaatcaatgc aaaaaacaag agagtcatca
    41401 gtttacacga tcaaaagaga tagcaggccg cttccttttt caatcttata gatagaccat
    41461 gggtaacgat aaaaacaaaa aagaacttgc gacttatttt gccgtaagtt cttttttagc
    41521 tagtgcctta atctcttaat cccaacaaac gtctcgcata gatcacctga ccagagtgca
    41581 tagcagcatc atcaataata gaaacgagac gcattcctcg tgtgactggt ggtgtccagt
    41641 tctcgtcaat tacttcatct agctcggaag gttccagcct tcttaagtaa gaaatagcaa
    41701 aatcagcagc tcctcgcaag tatcctagca gatcttctat ttgattagct tggatctgct
    41761 ttgcttgttc cagactatgc ttccaatctt gttcgttatc tgctatcgtc atcggaaacc
    41821 ggctttccca gtcttgacta tgccaaattg gagaagttcc tgctaaatca gcaatctgga
    41881 aatctaattc tcgagcggta tgccaagcca gccaagtcat tgatttgatc tgcggggctc
    41941 tatcttccac tggaaaacga ttggcctcct caatagagac gccttcaaac aaacgttcaa
    42001 accgatcgta tgcccgatcc acactctcgc atagcatatc taaataatcc atttattttc
    42061 ctccttttta tttatcctac ttactttttc ctaattctag gatacctact tatatgttac
    42121 tacacaccct tattttttac actttaacag tcaccatcat caatagtttg gagattgaaa
    42181 gaaaaagata gtgtcgaact atcaattgaa caagaagcaa caatatgaac gtttcattaa
    42241 tattctttaa ataaacaatg atttttcaaa cgaacagttt aagactagga gaaaaagagt
    42301 ataataggaa aatgtttgaa aggaaaggaa ggggaaaaat gaaaaaaagg gcaagtttac
    42361 tagtcctagt tgctttgttg ttcaatatct tttcgtatgg tgtggccgtt tcagcggaaa
    42421 catacattcc taaagaccct gggaatattt ataatgatct aactggtaac tatggcttgt
    42481 taggaattgc tagtcaattc cacgtatttg ctaaaaataa gacaactgtg aatgcacata
    42541 cagacggaaa tatagcaaca catgaacttg atgcaaaaaa taattttggt acagagcttc
    42601 atgaaggttt attgaaccaa gaaataaatt atatacaaaa aactgattct ttcgctaatt
    42661 cttcaggcat acctacaggt agcacaagaa tgaataaatt tgtcgttggc agtaacgtgg
    42721 atgtagcact tcaagatggt catcctacag tcaatggatc caggcttgat cacttaactc
    42781 cagatgattt ttataaagat cgtgctgggc atgaatatat tgatttcgag caggaatttg
    42841 ctaaattgaa tgtagcagca aatgatcttg caacgatcac tccagctaaa acatatactg
    42901 ctgcagattt tccagacatg aacaatcgga caatcgattt aactgattta tcagataccg
    42961 ggtttttatt ggtaaatatc gatgcagaag tgttaacgat gaatacgcca cttcaaatca
    43021 ttaatccaaa tgatcaagta gttgtattta atgtcatcaa cagttcttct gcattgaacg
    43081 tacagtcacc aatcaaatac aatgatcgtt caaatcatga aacagaagat ttttcggatg
    43141 cgaatatctc ttggaatttt ggaaatgaga tgactgattt gacaatcagt gctccttttc
    43201 aaggaacaat ccttgcgcct aatgctacta tccgcattac tcaaaaccaa gacggaacga
    43261 ttataggaac aaatgtgatt ttagatgcag ctaccaatcg ttgggatcct aacgaaatat
    43321 ttatcagcga caatggtaca gatacgacag acacaagcga cagtacagat acatctacca
    43381 caagtgatag ctcagattca tca
//
LOCUS       DAIGWC010000017        41835 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.017, whole genome shotgun sequence.
ACCESSION   DAIGWC010000017 DAIGWC010000000
VERSION     DAIGWC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41835
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.017"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            214..498
                     /locus_tag="NOB74_000934"
     CDS             214..498
                     /locus_tag="NOB74_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HCI1220136.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(815..1198)
                     /locus_tag="NOB74_000935"
     CDS             complement(815..1198)
                     /locus_tag="NOB74_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HCI1220137.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(1200..1784)
                     /locus_tag="NOB74_000936"
     CDS             complement(1200..1784)
                     /locus_tag="NOB74_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HCI1220138.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="NOB74_000937"
     CDS             complement(1831..3306)
                     /locus_tag="NOB74_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HCI1220139.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="NOB74_000938"
     CDS             3487..3798
                     /locus_tag="NOB74_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220140.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="NOB74_000939"
     CDS             complement(3913..6249)
                     /locus_tag="NOB74_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1220141.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="NOB74_000940"
     CDS             6391..7059
                     /locus_tag="NOB74_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1220142.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="NOB74_000941"
     CDS             7062..8105
                     /locus_tag="NOB74_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1220143.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="NOB74_000942"
     CDS             complement(8342..9223)
                     /locus_tag="NOB74_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1220144.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="NOB74_000943"
     CDS             9382..10110
                     /locus_tag="NOB74_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HCI1220145.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="NOB74_000944"
     CDS             10266..10583
                     /locus_tag="NOB74_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI1220146.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="NOB74_000945"
     CDS             10576..11184
                     /locus_tag="NOB74_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HCI1220147.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11239..12030
                     /locus_tag="NOB74_000946"
     CDS             11239..12030
                     /locus_tag="NOB74_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HCI1220148.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            12168..12656
                     /locus_tag="NOB74_000947"
     CDS             12168..12656
                     /locus_tag="NOB74_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HCI1220149.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="NOB74_000948"
     CDS             12707..13579
                     /locus_tag="NOB74_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCI1220150.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="NOB74_000949"
     CDS             13755..14117
                     /locus_tag="NOB74_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI1220151.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="NOB74_000950"
     CDS             14126..14878
                     /locus_tag="NOB74_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220152.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="NOB74_000951"
     CDS             14892..16694
                     /locus_tag="NOB74_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220153.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="NOB74_000952"
     CDS             16971..18011
                     /locus_tag="NOB74_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI1220154.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="NOB74_000953"
     CDS             complement(18063..20207)
                     /locus_tag="NOB74_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI1220155.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="NOB74_000954"
     CDS             complement(20564..21937)
                     /locus_tag="NOB74_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1220156.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="NOB74_000955"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="NOB74_000955"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HCI1220157.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="NOB74_000956"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="NOB74_000956"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCI1220158.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="NOB74_000957"
     CDS             complement(23385..24398)
                     /locus_tag="NOB74_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI1220159.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="NOB74_000958"
     CDS             complement(24479..25078)
                     /locus_tag="NOB74_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI1220160.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="NOB74_000959"
     CDS             25264..25965
                     /locus_tag="NOB74_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220161.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="NOB74_000960"
     CDS             25975..28686
                     /locus_tag="NOB74_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220162.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="NOB74_000961"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="NOB74_000961"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HCI1220163.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="NOB74_000962"
     CDS             complement(30825..32006)
                     /locus_tag="NOB74_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI1220164.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..33781
                     /locus_tag="NOB74_000963"
     CDS             32258..33781
                     /locus_tag="NOB74_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCI1220165.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33850..34578)
                     /locus_tag="NOB74_000964"
     CDS             complement(33850..34578)
                     /locus_tag="NOB74_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1220166.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34591..35871)
                     /locus_tag="NOB74_000965"
     CDS             complement(34591..35871)
                     /locus_tag="NOB74_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI1220167.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(36012..36614)
                     /locus_tag="NOB74_000966"
     CDS             complement(36012..36614)
                     /locus_tag="NOB74_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCI1220168.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36859..37065
                     /locus_tag="NOB74_000967"
     CDS             36859..37065
                     /locus_tag="NOB74_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220169.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37377..38096
                     /locus_tag="NOB74_000968"
     CDS             37377..38096
                     /locus_tag="NOB74_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI1220170.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(38177..38860)
                     /locus_tag="NOB74_000969"
     CDS             complement(38177..38860)
                     /locus_tag="NOB74_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HCI1220171.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            39079..41265
                     /locus_tag="NOB74_000970"
     CDS             39079..41265
                     /locus_tag="NOB74_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCI1220172.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            41611..>41835
                     /locus_tag="NOB74_000971"
     CDS             41611..>41835
                     /locus_tag="NOB74_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCI1220173.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELT"
BASE COUNT        13599 a         7390 c         8386 g        12460 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttattt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataac ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg agaattggcc
    33721 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    33781 ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt
    33841 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    33901 gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat
    33961 aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt
    34021 ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg gcgctcctag
    34081 cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc
    34141 tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa ttttgctcag
    34201 gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg
    34261 ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat
    34321 ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact
    34381 gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc
    34441 attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat
    34501 catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca
    34561 aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga
    34621 aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc
    34681 atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt
    34741 ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac gaatcatcac
    34801 ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc
    34861 ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt
    34921 atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt cctgtgccat
    34981 catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact
    35041 tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gatcataata
    35101 agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt
    35161 ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat ctttgatata
    35221 atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct tattagagat
    35281 tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga aaaaactcgt
    35341 attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa taatgatata
    35401 gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca cagtgtgaaa
    35461 ccaagtctct aacgattttt ttaaacaaaa agctaataaa gcagataaaa aagcggataa
    35521 gacaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt tcaaaacaaa
    35581 aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc caaaaggaag
    35641 cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc
    35701 tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa tcaaaataca
    35761 agaaatcaga atgactcccg caaacagata tttgtatcgg atgtgatggt caatcaataa
    35821 gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca taaagtacag
    35881 ctcccattga tttttaccaa attatagcac aattggcgta ttattttttt aatttttcag
    35941 ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag tcagataagt
    36001 tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt catcaagtag
    36061 tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa ataggtagaa
    36121 aagtaagaag ctgagaaaaa taacgtaatg agagaaaaaa ttagaaacat gctgatcgcc
    36181 ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt acctcttgat
    36241 ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat tgggaaggag
    36301 atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag tagtgtccac
    36361 agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg gatgcagata
    36421 taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga aaagactaga
    36481 acgaccgcta gttttccaag attattcaat aaaacttcta agacaaattt tacttggaca
    36541 tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa tttgttcaca
    36601 actttatctt tcatctcata cgtacctcca ccacaaattt tatgctaaaa aaaataaaaa
    36661 acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatc tcctaaaaaa
    36721 atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga aaagtacttt
    36781 ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaattactga ccttataaaa
    36841 ggtgatggag ggattcttat ggaaaatgaa caattgtttg aagtcggcga aacatatgca
    36901 tttaaatctg atttatttga atcaccaata aaaggaaaaa tagaaaaaat ctatgaaaat
    36961 agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc tcataatctg
    37021 cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca gataaaatgt
    37081 tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg aataatgtta
    37141 aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg gcaggagaat
    37201 actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta ttttcatgaa
    37261 taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat aaagtcaagg
    37321 cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca ggaaggatgc
    37381 cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa
    37441 tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat aatgaagtat
    37501 tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt ttctttttga
    37561 acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta ctagaccgct
    37621 ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag
    37681 tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta gaagaaattt
    37741 cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa actatgttag
    37801 cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct gaactctatt
    37861 cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt gatatatgtc
    37921 ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca tgtggagaac
    37981 aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca gatgcccagt
    38041 cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact aaataatata
    38101 aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct tgcttagttt
    38161 ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc cataaatgaa
    38221 atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc
    38281 caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca agaacgacac
    38341 ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa taatcatata
    38401 agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag gcacgcccgt
    38461 tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa atcgttacta
    38521 atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact gcttcataat
    38581 atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca attagatact
    38641 ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta ccaacactta
    38701 gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt tgagcagagg
    38761 caaaagcacc atattggata taagtataac tgtccatggc tcctccgata aatgtcagca
    38821 aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc accttttatg
    38881 aatatttttg tcttccttat cttagcataa acgattgaaa aaaaaggaaa aattttcaga
    38941 aaactaaaat catatcgctt cccattttca tttttagaaa ggtctgttag tataaagaaa
    39001 aaatagacaa cgaaacttta aataaccaac ttgaaataaa caaattcaaa gaagaaagat
    39061 gggaaggaaa tcaatcagtt gaatgaaaaa gaaattctcc gattacaaaa agaattgaaa
    39121 cgctgggaga acaagtataa aaagcttcaa caagtctttc ggctacaaga agaaatcatt
    39181 gctacctatg aagcggctta tggcgaagca cccggactta ttgaggaaga agtacaagta
    39241 aaagaaagtg aaggaaacag ctctttcttt aaaatgatgg agaaacgttc ctataatcgc
    39301 ttcaatcaag aacaaaaagc agctatcaca tatgatatga agaaacatct tcgaatcata
    39361 gcaggagctg ggagcggcaa aacgcaaaca atctgtgcaa aagctgttta tctgatgacg
    39421 caaaaacaag tagacgaaga acgcatacta atgatcactt ttacaaggaa cgctgcaaat
    39481 gaactaaaaa aacgagtaga taatttcagc cagagaaaaa ccgctgtcca tatcggaaca
    39541 ttccatagta tcttttttag gatatacaat gaaatttgtc gaaaatttcc tgaagtagca
    39601 atgcaaggaa tacaaggaga cttttcaaag gatactgcac aaaaagtgaa tgctgttttg
    39661 caacagctga tacgtaaata taatctttat atatttgatc aatatggaga aaaaacgatt
    39721 gcttctcggt tagactattg gcagaatatg aacctttcag tagaagaaat ggttcagtta
    39781 gttaaagaaa aatatgattc cattgataag aatgcacgac agccgatatc agaacgactg
    39841 tatggattgc tcacggaact ccaagaacaa aaaagaagcc agcaattgct agagttcaat
    39901 gatgtactcc aaaatctgaa aagcgctttg gagaatgagg agatccagca ttatatcggc
    39961 caaaaatatg attatctatt cattgatgaa tttcaagata ctaatccact tcaatgggaa
    40021 atcgtgaaac ggatgacaaa ggaaaacagg atcaagttga ttgttgttgg agatgatgat
    40081 cagagtatct atggattcag aggatcagag ccagcataca tcaagaactt tgaaaaagaa
    40141 tatcctacca aaactctttt cttattaact aattatcgtt ctcgggcagc tattgtccaa
    40201 ggagcaaata gattgatcag ctataataaa aatgatcgga taccaaaggc gatgattcca
    40261 gcacaaaaag aagcaggtgt tatggaagcc tatttgtttt ctgatactaa agcagaaagt
    40321 cagtggctaa tcaaacaaat tcagacattt attcaaaaaa atgggaaata taaggaatca
    40381 atcatattat accgatcagc ttcacaaacg cagcagcttg tccaatctct gctgaaaacg
    40441 aatattcctt ttgtactgga agcagatagt ccatatgaag gtatctttgg tatcaagtct
    40501 ttccaacatt tctatcaaaa aattgttcat tggcaaacag cactgaatct gcaaaagaaa
    40561 aatcaggcct accagcaatt gctccggcag ctgatggcag actgctacct gaaaaaaagt
    40621 gaatgcgatc aatacttttc tcctaaatat caaaatatag ccgttgcaga ttatattttg
    40681 tcgataagcc ccaatttaaa atcgaaatct gcagaaatcc gagagtttga ggaagcgttg
    40741 cgtaaaacag accagcatca agaaatctat tcgcttgttc aaagctatct tcatctgcca
    40801 cgtatagcta aggaaatcga ccagagtgat caagaatgga tacgagaaga agtaaagcag
    40861 catgctactt tcagaagact ccaagcctta tcgcaagaaa cccaagcgac agctaaagaa
    40921 ttaaaaaccc gcttgattgc ttacagacaa ggaaaacttg atgcactatg tatccagagc
    40981 attcacaaaa gtaaaggtct tagttaccga aatgtctttt tgattggttg taacgaagga
    41041 agtttgcctt ataacggagc gacagaaaag aaagtaatcg actttaatga aataaaagca
    41101 gaaccagtaa cgacgataga agaagaacga agactatttt atgttgcgat gactagagca
    41161 agaaatcgtc tgtatctatg tgtacctcaa atgaaaaatt caagaaaatt gaaagtatcg
    41221 agatttatca aagaaaccgg gagtcgtgtg aaaaaaggaa agtgatagaa gagagggtgt
    41281 gacagaagtg gtcagtttca agaaagaaga aggaatgtac gaaaattgct tctcaaattt
    41341 ttgtgaaatt tcagcttatt ttcgaagaag ctatttctgg aacacagttt attcggaaaa
    41401 gggaggtgtg acaagaattt tgtcacacct cccttattta ttttgaaaat gagaatacta
    41461 ttatcaaaat agagaatata tagaaaaatt ctcattattc aaacgtaaat aatcagttat
    41521 tttgattttt tttatatttt attagctaat aattggtatt ttaaaagaaa ttactgtaga
    41581 attggattat aattaaaaag gagtgagaaa atgataaaag tatatacttc gcctagctgt
    41641 acttcctgta gaaaagcaag agcatggttg caagcgaatc aacttgaatt tgaagagaag
    41701 aatatttttg ccgaaccgtt aacagaaagt gagatcaaaa agatcttggc agcgactgaa
    41761 ggaggagttc aagatattat ttccactcgg tcgaaaattt acgaaaagct gggcatagat
    41821 tttaacgaat taact
//
LOCUS       DAIGWC010000018        38107 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.018, whole genome shotgun sequence.
ACCESSION   DAIGWC010000018 DAIGWC010000000
VERSION     DAIGWC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.018"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(428..1372)
                     /locus_tag="NOB74_000972"
     CDS             complement(428..1372)
                     /locus_tag="NOB74_000972"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCI1220174.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1668..2612)
                     /locus_tag="NOB74_000973"
     CDS             complement(1668..2612)
                     /locus_tag="NOB74_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220175.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2833..4047
                     /locus_tag="NOB74_000974"
     CDS             2833..4047
                     /locus_tag="NOB74_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1220176.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4069..6084
                     /locus_tag="NOB74_000975"
     CDS             4069..6084
                     /locus_tag="NOB74_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HCI1220177.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6167..7540)
                     /locus_tag="NOB74_000976"
     CDS             complement(6167..7540)
                     /locus_tag="NOB74_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI1220178.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7566..7850)
                     /locus_tag="NOB74_000977"
     CDS             complement(7566..7850)
                     /locus_tag="NOB74_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1220179.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7852..9867)
                     /locus_tag="NOB74_000978"
     CDS             complement(7852..9867)
                     /locus_tag="NOB74_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI1220180.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10046..10351)
                     /locus_tag="NOB74_000979"
     CDS             complement(10046..10351)
                     /locus_tag="NOB74_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HCI1220181.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10440..11471)
                     /locus_tag="NOB74_000980"
     CDS             complement(10440..11471)
                     /locus_tag="NOB74_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1220182.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11678..12553
                     /locus_tag="NOB74_000981"
     CDS             11678..12553
                     /locus_tag="NOB74_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI1220183.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12705..13547)
                     /locus_tag="NOB74_000982"
     CDS             complement(12705..13547)
                     /locus_tag="NOB74_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1220184.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13639..15516)
                     /locus_tag="NOB74_000983"
     CDS             complement(13639..15516)
                     /locus_tag="NOB74_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI1220185.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15513..16934)
                     /locus_tag="NOB74_000984"
     CDS             complement(15513..16934)
                     /locus_tag="NOB74_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI1220186.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16937..20326)
                     /locus_tag="NOB74_000985"
     CDS             complement(16937..20326)
                     /locus_tag="NOB74_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCI1220187.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYRKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20583..21974
                     /locus_tag="NOB74_000986"
     CDS             20583..21974
                     /locus_tag="NOB74_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220188.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22047..22694)
                     /locus_tag="NOB74_000987"
     CDS             complement(22047..22694)
                     /locus_tag="NOB74_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCI1220189.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22702..23388)
                     /locus_tag="NOB74_000988"
     CDS             complement(22702..23388)
                     /locus_tag="NOB74_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220190.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23394..24467)
                     /locus_tag="NOB74_000989"
     CDS             complement(23394..24467)
                     /locus_tag="NOB74_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220191.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24689..25363
                     /locus_tag="NOB74_000990"
     CDS             24689..25363
                     /locus_tag="NOB74_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1220192.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25368..26708
                     /locus_tag="NOB74_000991"
     CDS             25368..26708
                     /locus_tag="NOB74_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1220193.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26857..27843)
                     /locus_tag="NOB74_000992"
     CDS             complement(26857..27843)
                     /locus_tag="NOB74_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HCI1220194.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            28567..29598
                     /locus_tag="NOB74_000993"
     CDS             28567..29598
                     /locus_tag="NOB74_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI1220195.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            29707..31239
                     /locus_tag="NOB74_000994"
     CDS             29707..31239
                     /locus_tag="NOB74_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HCI1220196.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            31378..32190
                     /locus_tag="NOB74_000995"
     CDS             31378..32190
                     /locus_tag="NOB74_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HCI1220197.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            32180..32665
                     /locus_tag="NOB74_000996"
     CDS             32180..32665
                     /locus_tag="NOB74_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI1220198.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            32688..33233
                     /locus_tag="NOB74_000997"
     CDS             32688..33233
                     /locus_tag="NOB74_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HCI1220199.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(33306..34949)
                     /locus_tag="NOB74_000998"
     CDS             complement(33306..34949)
                     /locus_tag="NOB74_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCI1220200.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(35078..37306)
                     /locus_tag="NOB74_000999"
     CDS             complement(35078..37306)
                     /locus_tag="NOB74_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1220201.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(37339..37818)
                     /locus_tag="NOB74_001000"
     CDS             complement(37339..37818)
                     /locus_tag="NOB74_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220202.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT        11115 a         7210 c         6922 g        12860 t
ORIGIN      
        1 tttaaaaaat gataaacctc tctcgaacgg ttttttatca aaaatcgtca tttttccatc
       61 aaaatctgct tatgcaaaat tataaaaaaa ttttgcagtt tttcttactt tttttgtcgt
      121 ttaattgaat gataaaaacc agtttcttta ttcagttaat caaatatgaa cgaattagat
      181 atgaatcatt gtatttgccg ttgcggaagg attttttaat taaccacaga taaacattga
      241 taacgattcg cttattgtaa tcaacagatt aaatttcata tgttcatatg tacggataca
      301 ttttcggacc gattaatttt aaccattcta tttatttgct tacctattag atatcaataa
      361 aaaactgctt aacagctatt tcagctgtta agcagtttta ggatttttag ttcatattca
      421 ttgtttctta taatacagtg ttcaatactt ctcttaaagc acttgttgat ttgctgaaca
      481 ttgctttttc ttcttcgttg attgataatt caacaacttc acgaacacca ttttcgtcaa
      541 cgattgatgg cacacctgta aagatatctt tttcgtcgta ttcaccagtt aaataagcag
      601 atacaggcaa tacagcttgt tcgttattca agatagcttt tacgatacgt gcagtactca
      661 taccaatacc atagtaagtt gcttttttac gatcaatgat ctcataagca gcattacgga
      721 ctttatcagc aatcacatct aattcatctt gggcaatacg atggtctttt tctacaattt
      781 caaacactgg tttaccaccg acagttgtat gtgaccatgc agcaacttct gaatcaccat
      841 gttcacctaa gatatagccg tggacgctgc gtgggtcaac ttttaatttc aatgcgattt
      901 ctttacggaa acgagttgta tccaatgttg ttccagtacc gataacacgt gatgttggca
      961 gaccagattc gttccaagcg atatatgtca aaatatctac tgggtttgaa gcaacaacga
     1021 taataccgtc gaatcctgat cccatgattt cttttacgat ttggcgcatg attgacgcat
     1081 ttgttttaac taaatctaaa cgagattgac caggtttttg gttgatacca gctgtgataa
     1141 caacgatatc agcatcttta cattcttcat agccacctga ccatacagcc acattttcat
     1201 cgccccaagc cataccatct aaaaggtcca atgcttcccc ttctgctttt tcttgattca
     1261 catcgatcaa tactaattca ttagagattc cttggttgat cattgcataa gcgatacttg
     1321 ttccaacaaa acctgtaccg acgattacta ctttacgact tgtttttttc atgaataaac
     1381 agctcctttt cataactatt tgttactttc atgaaaagta tagtcttgtt tattcatttt
     1441 atcaacatgt taattataat agttgttatt ataatttttg atggaaacga attcctgaat
     1501 acgcataaca gataaatgac aaatgtttac acctatatcc cctgataata caaccaaaag
     1561 tttagaactg aaaataaatc caaaaaaatt cgctgcaacg atataataag acagcaatcg
     1621 cacctaaaac aattttcctt catatgcttt agtgaaagat tttcttctta atgtttattt
     1681 ctccattcat tgggagtaca tgttgaatac ttcttgaata atttgaataa agaagtcgtt
     1741 tgtttatatc cgatacgatt agcgatttct tccaacgaaa aactcgtttc ttgaatcagt
     1801 tccaacgcaa agtcgaattt tttctttaga accagttctt gaaaggaagc atcaaaatac
     1861 attttcaatt tattactaag atagaccgga ttgtagccaa aatgagctgc tgtttctttt
     1921 aacgtacaag aagtaaaatg cttatcgata taatctaata ctctaagcat ctcattttct
     1981 gcgcatccat ctgctgatga aaagctttgt tgttctaata aatgagtcaa ttcgatcagt
     2041 aatagtgatg tatagagatt taacgaacgg atcttatgac tgtatgtatc aaaataaatc
     2101 aacagcatat tttcaatcaa atgcgtcaaa cgacttgttt ttccgccgcg aaaatgaatg
     2161 aattgtgtat gttccccttt ttcttttgat gcatttatca aaaaagaaga aagtagatta
     2221 tttgtgcttg ccaaatgatt caatatctct gtagataagg tttcttcttt taataagatg
     2281 ttgattaaaa tatcctcttg ccctgtgtat tcgattcttt gagtagcttc tttatcaatg
     2341 atcaccacgt cactttcttc catctctatc ctttctccat taataatttg taaacatgta
     2401 ccgctataca tataattgat ttcaacaaaa tcatgtgtat gctcgggaac ttccgcatat
     2461 cgacggtgtt tactgatatg aatatttccc tgttgaaata gatcccctcg gtggattttt
     2521 ggcggtgtct gaagatggta agctaagttt aaatcattga tattcattcc ttgttcacgc
     2581 tgcagagttt cgattgattc ttcgttacgc aaaaaaaatg tctaattcag ctagttccaa
     2641 ttgactccct cctttttgta agcggtttct ttcgcttatt agttcacgct gtactgctat
     2701 tatatgcaaa gctatttttg gtttcataaa gactttctat ggttgggaca tgaacttcct
     2761 gtgattccgc tattgagaga ataaccactt catactatat ttttgataag cgcttacaaa
     2821 aatgaaagga acatgcttat gaataaaaag atgatgaaat tttctctgct gtcagtctct
     2881 cttattttga cttctgctgg tgcagtcacg tctgcaattc ccagtatgtc agctacttat
     2941 gccacgcgtt ctttatctgc tgttgaatta ttaacgactg ctccctcttt tatggtcact
     3001 atttttgttt tgattagtag ttttattgct aggaaaatcg gacaaaaaca aactgtgatc
     3061 atcggattag tgattgcatc gatttgtggt atcctccccc tcttctcaca aagttacagt
     3121 attgtcttag cttcaagagc tggactaggt attggctttg gattgatcaa ttctttggca
     3181 gtcagcatga ttgctgcctt ttatcacgga gatgaacgag cctctatgat tggttttcaa
     3241 agtgcatttc aaggatttgg tgcagcttta atgacatttg ttgcaggaca gctagtacag
     3301 ttcggttggc aatatacctt tttagtctac gccatcagct tacctattct tgtcttgttt
     3361 gttttgtttg ttcctacacc tgaaacaact gaacttcaat cgcatggcac agccccaaca
     3421 agacaagtaa tcaaaacgaa tcctaaaatg attagttatg gtatttttct cttgctggtc
     3481 atcgtggtat ataatgctgt atcgattaaa ttagccacag tcctgacgac ttattctcta
     3541 ggaaacgaaa ctaatgcagc gaatatctta acaatcatgc aattggcaag tatggctgcc
     3601 ggagtttgtt ttggctggct tcagacaaaa gcacatcgct atatgcttac actttcttta
     3661 ctactgatgg gaatcggctt tgtattgatt gccactgtga taaacctgta tgtgattggg
     3721 tttggtgcga tcctaacagg aatttctttt tcgttattca ttccttactt attcaaccaa
     3781 gtaagtatcc aagcgcccaa gtacgcggag agtttcaata cttcaatctt attggttggc
     3841 gctaatttag gtactttcat tgcaccatat ggtttgctct ttctctcttt tgcttctctt
     3901 gggagtaaaa cacttgctgt tttcgtcaat ggcagtatct tgctgttgat tagcgcgctt
     3961 attagccttc tagtagtaca caggacgaat agaaagacag tgataagagt agatgaagaa
     4021 ataaaagaac aattgacaac aaaataaatt tgatggaggt cgtgtaaaat gacaaatgaa
     4081 aaacataaag atagatggct ttggtatcct ggagactttg agatccgcca tggactgcta
     4141 caaaatttcc aacgggaaga acgaggtttt gactggccag cgtactggta catggatgat
     4201 tgccatcgga acgtcaagtt taagagatat tactttcttg atcaaccttc catgtttaaa
     4261 gtgacgatcc aaggagttgg gtatgtagaa attaatggac aaaaacatcc atgtggaaaa
     4321 tggctgactt gtccagctgg taaagcaaaa attcgtatct ttgtaggaca tacatcaggg
     4381 ctaccagcga tgtttatcga gggagacgaa gtaaaatcag atattggctg gacagcaagt
     4441 aattttattg aagaatatcc agctggctgg agtccgcttt atgtcgatat cgcaaaagat
     4501 ccaaatcaaa tctattatca aaaagaatgc gtccatccag tcactgaaac ggagattggc
     4561 ggaggaatct tattcgattt tgggcgagca gtgaatggct gtgtagaact aatatctctg
     4621 gatgaccata tcgaatctat cactctatgt tatggagagt ccgatgtaga agctatggat
     4681 atcgattatt gctactataa gcaaatagga atgacaagaa aaatgaaagc tcgtaaacgc
     4741 gcttttcgct atttgtttat accagaggtt tctactggaa tggttcaact tcaagttttt
     4801 catgaatttt tatctctttc gaaacaagct gctttttcaa gcgattcttc tttactgaat
     4861 cagatctggt cagtatcaga agaagccttc aagttatgta gtgatttgtt ttttatcgac
     4921 ggtatcaaac gagatcgctg gatttggtct ggagatgcgt atcaatcatt catgatcaat
     4981 caatatcttt tttttgacga ggaaatcaat aaacgaacga tattagcatt aagaggacaa
     5041 aatgaaatca agcagcatat gaatactatc gttgactatt cgatcttgtg gttgattggt
     5101 atcgaaaacc actatatgat gacgaaagac tatgaatttt tacgcatcgt ctaccctaag
     5161 atgcaatcat taatgagata cttgatggag caaacgaatg aattagggtt tatttatggg
     5221 agagcaaaag attggatatt tattgattgg tctgaaatgg ataaagaagg aacgcttgct
     5281 gcagaacaag tcttattact gaaagcctat cattccatga tcacttgcgg agatatctta
     5341 gctgaaacat atggagagaa cgaaaattat catactcatc tctatcaaga aaaatatcaa
     5401 ctattgaaac aaaacctatt tgactacttt tgggatgaag aacttggcgc ttttatcgat
     5461 tgctatgaat ctgggagaag aaatgtgacg cgtcatgcga atattttcgc tgttttattc
     5521 gattttgcta acaaagacca acagcaatcg atcttaaaga atgtcttatt gaatgacact
     5581 atcacacaga ttactactcc atatttcaaa ttctatgaac aagatgcttt atgcaaactc
     5641 ggacagacga atatcgtcta ccaaacgatt cttgattatt ggggagggat gttatctcat
     5701 gatgcggtaa ctttctggga agaatacgac cctactcaaa caggaaatga aaagtacagt
     5761 atgtatggag atccttatgg aaaaagctta tgccatgcat ggggagcaag cccaatctat
     5821 cttttaggac gctattttat cggtttgtat ccaacaaagc caggttatga agaatttatg
     5881 atacaaccta atctagattc atttgaaaca ctgaattgta cgctacctat caaagatgga
     5941 aagatttcgc ttgaaaaaac aaaagataag atcgtgatta cttctgatag aacaggcgga
     6001 acagtgaaaa tgaatggtaa aagttatcct cttctagcaa aacagccact tgtcttaaca
     6061 agctattcaa aaataaatgc ataaaacaaa aaactgcttg cgacatatca gaagacttta
     6121 aatcttcttc tgatattgtc caagcaattt ttattttgaa gtttgcttaa ttctgttctt
     6181 tagaaacaat gtttgttctt tttccggcaa aaagaaagct agataatacg acaagtaaaa
     6241 agaaagcgat gattccaact gtcaaggcta tttgaccgta ttctcctagt ttcccaagta
     6301 caagtcctgg tactagataa tcagtatcgg caaatgtaga agaagcgatt ttaagatctc
     6361 ctaatactgg aaggataaat aatggcagcc aactaatcaa taagctattg aaagcagaac
     6421 ctaataccgc ccctcttcta ccgccagtcg agttgccgaa gacaccagaa gcagctccgc
     6481 agaagaaatg tcctactacc ccaggaatga taactgtagt ttgcaagcct atcatagcaa
     6541 acatggatag tgttcctaca aagaagctaa caaaaaagcc aattaataca gcattaggtg
     6601 catatggaaa aacgatagga acatctaatg ctggtttaga atcgggtacg agttttttag
     6661 caatcccttg gaatgctgga acgatttctg ccaacaccat tcgaacccct tgaaggacga
     6721 taacaaaccc agctgtgaat gttccagctt ggatcagtgc aaagattaca gcgttgtctc
     6781 cattgcttag ttctctttca acaaatccag gaccagctaa caaagcaagt gcgacatata
     6841 cgatcgacat caagagcatg atcgatacag tagaatctcg caaaaagctg aaacttttag
     6901 gaatctttat gtcctctgta gaacggtctt tgtttccaaa aaactttccg atccatccac
     6961 tagaagcata accgatattt ccggtatgcc ctaacgcaac ttgattgttt ccagtgatgt
     7021 tcttcataaa cggttgacaa agagcaggcg taatagttaa tagtgttcct tcgaagaccc
     7081 cgcctaataa gatcatccac aaatttgcag taaaccccgc gcttactaaa atgactgctg
     7141 ttagacaaga aacataaagc attgcttgac ctgtaagaaa aatgaattta tatcttgtga
     7201 atctagcaag taaaatattc acgatcatcc ctactagcat gatcaaagca gtaggtgtac
     7261 cgtattgttg caaagcaatc gccactactg cttcattgct aggaactact ccttgagtat
     7321 gcagagctgt ttggaacatc gaagcaaaag gggttagtga attactgatt aaaccagcac
     7381 cgccgatcag tactaggaat ccgacaaatg ttttgatagt tccttggatc acttctgaaa
     7441 atttcttctt ctgaagaacg agaccaagca gtgcaatcaa agaaacgagg atggagggct
     7501 gactgacgat tgacacaaac aaattcaaca atttatccat tgatagttcc tcccttgaat
     7561 catttttatt cttttgacaa gatcttcgtt actttttctt ttacttcttc gctgtcaatg
     7621 atcgattgca aaggtacgag cttttcatca ggtatagaag ttagcgtatc tttcaaagaa
     7681 tgctcaatga agaaataatc agccatatcg ctagatacac ttccaacatc cgtatgactt
     7741 acttcaaact cgtccacatc tgctccaaga tctgcaagtg cttgtttgat gttcatctct
     7801 accataaaac ttgttcctaa tccactttga catactgcaa aaattttcat atcattcgtc
     7861 tccttttctt atgatcgcta atatttcttc ttttgttgat gcgtgtaata aatcttgaag
     7921 attttgttta ttagaaagta gctttgttaa atttgccaaa gcccgaagat gtgcctcatt
     7981 atcgatagca gctaaacaga tgaacaaact aatgggatgg gctggattat caagcagatc
     8041 cacaggttgt tgaagtttca gcaaagacat ccctacttcg tttacgccat cttctggacg
     8101 agcatgaggt aatgcgatgt gatcgccaat atggataaac gcaccatact gctccacgcg
     8161 ctcgatcata gctttgatat aactttcttc tattttattt tctgataata gcggctgtgc
     8221 ggcaaatgtg attgcttctt gccagttttt tggttgatcc gataattgga tcatttcttc
     8281 tgttaataat tcagatagca taggacgttg atcctccttc ttttctaaaa gtttgttcat
     8341 tttacgattt aatacttgat agagcttttc ttcgtctacg ccttctttta attcgatata
     8401 aggcagtagc gccgacaaca attcttgggc agaaggcatt gaaaatcctg gtatcagcca
     8461 atctctttgt acttgattga tcagctgatt tttttccaag tcagtcatga ttggatgcag
     8521 aacatagaga gactttttct tatcagtaag tgtgagaggt acagtagaaa aaataatatc
     8581 gtaagaagtt tcgtcaacct cgtgtaagcg gtcagctgaa ttagtctctg taaaaaagat
     8641 catcgggaat aattgctgaa gttcactttt taagatcaat gaagagctaa tgccacttgg
     8701 acagacgatc acggctctta tttttctatt tctttcttct gcgtccgctt ttctgatctc
     8761 tccgccaaat agtatagtga aaaaaccaat ctcttcttca gggatgctct tccctattcg
     8821 tctttctaac ggaagtaatg cttttcttgt catttcgtag atggaagcat attgatgctt
     8881 aatttgatcg atcatcacat taggtaaata aaaagaatag gaaatacgaa aataggcagg
     8941 gaccaagtga taaaagacat tcatcaataa ttcacgaaac gaagcaaatt ctacggccat
     9001 caggaattcc atgcgatgga tgacttctga agaacattcc agcaaaaaat caagtgcagg
     9061 ctcctggaca tctccttcaa cgatcgatgc taagcaaaga gagaaaaata taatctccga
     9121 attttgatgt tcggaatagc caaggccagt caatacttgt cgactaatgt cagtgactgc
     9181 aagagaagcc aacagttcag catcttttac cagttccatg gatgtttttc caattcgaat
     9241 ggttgtcaaa ctcaaataat aagctaattc atccattcga tttggtgcga atcgaagatc
     9301 tgatagtgaa atcgttttat ctagcaaatc tctaactttg gcgtaataat caatggaaag
     9361 ggttgcggtt aaatacgtga gcccaaatct tccagcaagt gactgcatca aacgagcagt
     9421 gcgatttttt gcttctcttc ttaatattgc ttctgaccct agcagcctaa aaccagtttt
     9481 cctagtatac gacagctgac aatcttccac ttctaattca tttcttatct ttttgatatc
     9541 tgacaggact gtccctttag aaacctgaag aaaatcttga aaatgaaaaa cagaaacaga
     9601 cgttgcagtc gaataaacca tcaaataaag aagatctctt cgctcttgtt cggtatacac
     9661 agcttcaaat cgagtaatat ccaaaaattt ttctgcccag tcgattgctc ggaatttctt
     9721 tatacggata cgggtatcat ccacatattc ggcaaaagga gttaattgtt tgatcgcctc
     9781 gcttgtattt acttcgatga tctctgctgc tttttctaga ctgatttctc ttggtgtttt
     9841 caggagataa ctaattttgt agttcacagc gctgttcacc tcctacttat attctagtat
     9901 ggtagcgctt ttaaatcgag gggtgtttgg tacaacttac agttggattt tttttacgac
     9961 tgtaccgaac gatttctatc gaatggatac agaaaaaaag caggtgacca aatgtctcct
    10021 gcttttatga attgatttcg tccgatcaat gatgatcatg tttatttttt gaggtcagtt
    10081 cttcaaattt ttctttgaca tcttcaaccg ctttttcgat atctttttca aagtgattgg
    10141 gctcattagg ctttgtttcc tcttctacag aatttgaacc agataaagct gtttctttat
    10201 tttctgtttc accagagttt gtgccagcta atgattcttc tttgtcttct gtttcaccag
    10261 aattagttcc tgctaaagcc acttcttctt ctgttttagg ggccattgaa cctcttaatc
    10321 gtttgtgttt ttcaccgtca taatttgtca tgttggttcc tcctagtagt tctatacttt
    10381 ttcatcgtac aataagacag tttatgcgtc aaaaaacaaa cccgattctt acaaatatgt
    10441 catatttttc cttctgattc ttgaatgctt ttgattcctt cttccaaaat tttcatttgt
    10501 aagattgttt cttcatcttt gatgactttt tctgcgccat taactaatgt ctcgtaaatc
    10561 ccttcgtaga cacggctgta atcaccaacc tcggaaatta ctttttcttc atgataactc
    10621 ccttgttcat ctatataggt caatacacca taatgttcgg gcaaatcgat accaaagtct
    10681 tcatgatcag gcatgtaaaa cattttcaga tgttcttctt gtcgatcttt tgtttgtttc
    10741 acgaacatcc ctttttttcc gtaaacgacg aaacttggac gttctttgat gcggaaataa
    10801 ctggatttta tcgaaatttt catatttcca tagaaaaaat ccagatcgaa gtaatcattc
    10861 attcgtcctt tccctaaaag ttgacgtaca tcatagctga tatcatctgg ttcgccgaaa
    10921 taagaaagaa cttgatctac tgtatgacaa gcatgtccat ataaatagct gttcgcagta
    10981 gaaaattcat gcgtattttc tggtacttcc ggtctgaaat aatcataatg catttctact
    11041 tctaaaatat cccctaattt tccgctttcg attacttttt ggactgtcaa gaagtcagaa
    11101 tcgaaccgtc tgttttggta acattggata aatagacctt tttcttttgc taatgcaaat
    11161 aactcttctg cttcctttga cgtttctgca aaaggtttct ctactagtac attcttacca
    11221 tgttcgagtg ccatttttcc atattcataa tgaaattgac taggtgtagt gatgacaact
    11281 aattggatct caggatcatc ccaaagatca gacagctgat cagtatattc gatgtcttcg
    11341 aatgttttcc acactggttc agatggggaa aaaatttttt tgatattgat tttgttcgta
    11401 agttttcttg aaaaaggcaa atgatagcga tttgtactct ttccattgcc aagataagcg
    11461 attgtaagca tgagtggtgc ctccttttat tgatgttttc agtatatcct agaaaagcgc
    11521 agaaagtatt tataatagct attctggtaa aaaagttcag aaaaacactt gttatcattc
    11581 ggtttggtga aattaatgtt caaagtaagg ataaaaatca aaaagatagt agcggaacca
    11641 agtgtttatc agtaagatag aatttggagg tcagatcatg cttattgaag aaaaactaac
    11701 aaaacaagag ttgtttacca cgacagagaa acggattgtc gattacatcc gtaggaatat
    11761 cgaagctgca gtctacatga cgattgaaga attagcaaaa gctacgtata cttcccattc
    11821 agctatcatt cgtttatgca aaaaaatggg attcagcgga tttaaagaat tccgtttcga
    11881 gctggggcgg gaagttcatc aattgattgc tcagttcaat caaacgattg atcctaattt
    11941 tcctttttca agtgaagata gcactcagca aattgcaaag aaaatggcgg atttatcgat
    12001 ccagtcaata aaaaaagcac aattgcagat tgaacatgaa gatttagatc aaatcggtaa
    12061 agtattgaac aaggcacagc gaatctttct ttttgcaaaa ggtgattctc aaatcacggc
    12121 aaggaaattc cagaataaaa tggtcaagtt gaataagttt ttgatcatgg ctgaagaata
    12181 cagtgattct tcttggaatg cagccaattt gactagcgag gattgcgcca tttttattag
    12241 ctacagcggt cgcatccatc attatgaacg aataatgacc tatttgaagc atgtagaggc
    12301 ccctaccttg ctgattaccg gaaatcagca ttcagaaatg gccaaacagg ctgatatgtg
    12361 tcttgttata tcgcaggagg aatatgattt tgctaaagta gcgactttct cctctcaaat
    12421 tgccttcgat tacgtattaa atacgttatt ctcagtgata tattctcaaa attttgaaga
    12481 gaatatccgc aacttgaaaa acaaacaaga attgatgcaa aaaggccttc ttaaagaata
    12541 tcggaaaact taagaaaaga tcctcattta gtaataagaa agatagtgtt tgataggctc
    12601 tctttgatat catcataaaa acaggctgaa gttttctttt tcaaacctca gcctgtttgt
    12661 ttacggaacg attcgaatag atatattata gaaatgagga atagctaact tctgtttctt
    12721 attttgaacg attgacgaaa aagatatata agaaggagga aaatcagtat acatgcagct
    12781 aacaatccat acaggaaaaa tcgtttgttc tcggatactt tctgtacttc tttttgaact
    12841 tcttttgcat gataaggaac ccggtgccct ctgacaagta agcgatgact gttgaccata
    12901 taaggtgtac aagttaggag tgtcacgaaa tcctgccctt tttcgattct cagatctttt
    12961 gtatcagtcg gttctaccgt cttgatctga tcgacttgat aagcgagtgt ccgtccattg
    13021 atttcgatat agaaagaatc acctaaagtc agtttcggta agtctgtgaa caactttgct
    13081 tgaggcagtc ctcgatggct ggaaataacg gcatgtgtat tttctccccc cgtaggataa
    13141 gacgttcctt ccaataatga ggcacctttt tctagcagca cagtattcgt ttcatcaaaa
    13201 attggcaaat ggacattgat ctcagggatc gtcaaaatac cgatcgtatg tttctcaaaa
    13261 taggttctat cctttttcgc aggttctttt ttcttagtaa agggatctgc acctggattt
    13321 ccaccttctt ttgctaattg ctggtttttc tttgtcatgt tttcttggat tttagccatg
    13381 acttcttcat tttctttgac cgcttgttgc tgataatgag agatgatctg ctgatccaga
    13441 taattattca gcgcgtcgct aacaaatgga taagctagta tccctattcc tgagagaagc
    13501 aagaaaagca tcagcagatc tagaagtttc cttttctttg gtttcatttg tgttctcctt
    13561 gtgatgactg tttgataata aaagaaaaag gagcatttgc gtaatccgct gctccttttt
    13621 ccaattcttg caaaaagact aaatctgact gtgcttgcgt ctagcaaagt acagtccagc
    13681 aatcagtaga aggactactc ctgcaccgat atacacatag attcccttac cgcctgttga
    13741 aggaagtgta cctttgtgtt tatttggtat tttttcagga gaaatcaact gtcctgctgt
    13801 tacataagat tgttcatcga tagtaaatgc tacacggttt gttaatggaa catatttttc
    13861 tggcgctttc gtttcttcca gatagtacgt gccatatttt agacctgtca catcgattaa
    13921 accgttactt gtggttgtaa aaaccgttgc tgattctttc gccgataccc agctgacggc
    13981 ttttgtggat gggtcgatcg ataaatattt cgctgtgtca ctatcttgat cacgaacgac
    14041 gaattctgct ccagcaagtg tttggtctga tgtaacgtca ccatctactt taacaaatcg
    14101 tttgccccca gtaacgacat cgactgacgg tggtgtttga tcatttgtat gcccgttatc
    14161 gacatttgct tggttagaaa atcctttggt tggatctgct ttttcgttca aatgcatata
    14221 gtaaacgaat ttcaatgtac cgccaggagt taatgaagga atataattcg gatcaactga
    14281 aaccgtgaat ccgtctgttt gctcagtgac agaataattt actgggtcga tttctttatt
    14341 tccatcatat aaggcataag catacgttcc tgaagaatca ttatcaaatg ttaaagcagc
    14401 gtcatgagta tcgataagtt tgaatgttgt gtacttgttt tgcgttcctt ctttatcagc
    14461 gatacctaat gggatattga cagaaatctc atattgaatt ttttcaccga ttgcgacatc
    14521 ttttccattc aattgaggtg ttgttttatc aactttagac gtatcatttt tgatggtctt
    14581 ttctactggt gtttggctat ttgccaggat ctcaaaaggc gtgattgttt gcttttcaat
    14641 catttccgca ttatcaggag cttttacttc ttctaaatta tattttccaa cttctaaatg
    14701 attaacgatc aactggcctt tttcaataga tgcctcggca aagtcattgt tgccgatgtc
    14761 ataagaatga ccagtaatga aatgtttggc tttggtttga tcagttgtcc aagtgtacaa
    14821 tccatctgtg acactttgga tgtatttttt gacgcttggt gttccttctt ctttagaaat
    14881 aataaattct gctccattta gtgcttcgtt ttcggcagta ccgatttttg taactttcaa
    14941 cgttccatca ttaccgactg tatttttagg gtagagatgg atagtatcta gttcttctgt
    15001 cccgtattta taagagccat ctgcttgttt gatcatctca tatacaggga aagctaaaac
    15061 catgtttgcg gcagctgaca ctccgtcttt tggttcttct ttgatcgtgt agactgcatc
    15121 tttcccattt tgttttttag gtaaagataa agtgacattt ccatcagcat ctgtcgttcc
    15181 tgaagcaact ggtgtaccag gagtcaaaga ctggactgct tgttttgctg catccacgga
    15241 cgctccttta tctcgttgcg cataaaattc ttgagtgacg ttataaactg aaaatgaaat
    15301 atcggctaat ccttggtatt gatcgaattc gctcatttct ttcccgctgt tttggattaa
    15361 aggatcgggt aaatcagtca ttttcttttt atgaaggatg acttgagctg ctgtctcctc
    15421 tgcaaacact ttttttgcgc cgaagctgtt tgtgagtaat ggtaaaataa ggaaaaggac
    15481 tcctaacata acgtttattt ttttatgatt tttcattttt tcactcctgt tctttttttg
    15541 ataaacaacc agattgcaaa gcttgcgaat accataccaa caacgcctaa aagtgtattt
    15601 ttcgtttcgt ttgtttttgg aagaaatgga cggctatttt cttttttatt gactactttc
    15661 aatatactgt ccgcctcttt atcctcagaa agaaaagttg aaatggtaaa cggaatttct
    15721 gtttcactta aaatataacc agaaggtgct tcgatctctt ttaatcgata acttcctgtt
    15781 ttcaacccgg aaattgaaaa agcgccattt ttatcggaaa tcaggtgaag cgcatctgat
    15841 tcgttctttg tccacttgta tccgttggct gtttgctgga ggtaatttcc tgctttgttt
    15901 ttaataagga atactgcgcc agctaatcgt ttatctggtt tatttgtctc gattttgaca
    15961 aattgcttac tccctgtata tacagagact ttctttgtac tgacaccaaa accaaaatcc
    16021 agtgttccgt tgttgttgat ttccttgttc gcctgtgctg tactgcttag ctgcatctga
    16081 taagaaatgg tcagtttttt tccagcatat ttttccaacg aagggatcga aaataaaaca
    16141 tcaaatccgt gaggtttctt gtgtatgaca aagccttctg tcagcttttc tccattcgat
    16201 gaaatcgtta aactattagg taaaaacgtt aatgcttcat ccgcactatc tgacaattcg
    16261 aacttttgat agtcaaggat atttacagga attgtcgtat gcaaggaata agtgattttt
    16321 tcaccaatcg taaaatcatt tctaggctct tctaatacct tctcaaaagg tggatcaggg
    16381 tagtcgtttt cttcattttt aggatacaaa tggatagttg aaagtttttg attgttttgt
    16441 ccatgtacag gaagaacaac taccatattc tctgcctttt ctttgacgac ttctggtact
    16501 ttggattcaa tgaaaagata cgctttatct cttttttctt gatctttagc ggccagagaa
    16561 aaagaagcga taccatcttc gttgttaaga gttgtagttg ttgcttctgc ggtaaacata
    16621 ccggaagacg caccgttttt tgcgatctct gcttgtgctt cttctaccgt tttgcccttt
    16681 tcccgtagat ggtaaaaaga atctgtgaca tcataaactt ggaatgtgac accatttaat
    16741 cctcgatacg tttgtaataa agctttttct tgtccgtcat ttggatgatt tttcggcagt
    16801 tgcccgtttg ggaaaagcaa tttgtgtaaa gtaatctgaa ccatttctgt ttctgtttct
    16861 gttgctacct gagtaaaagc tggtttaaat agtaacaaga agagacacat actaagccaa
    16921 ccaagttttt tcatatttag ctgccccctc tttctttttt caaaaaaaga taccaaatag
    16981 aaaacgcaca accaatcatc cctactagat agattcctaa acggccaatt cctcccgttt
    17041 caggtaatgg tacttttgcc tgattcgtga tgtctaaaga aatctggttg tttttggctc
    17101 ctggtgacag aacagattca tgatcttgtc catccacttg aattgaccca tcttcgtgta
    17161 taactatagt aactggctct tttagacctt ggtatccttc tggtgtaaaa gtttcggtca
    17221 gcgtataagt tccaggtttt aaattttcga atagaaaggt atctgtttct tgtccatctt
    17281 ttggcgattc taagtccatt tctggtccct gcagtctgaa ttttgctcct tttaatgtct
    17341 gtccgttgtc ttcttttttg tgtaccgtta gatcaaacgc ttttagtcga ttttgatgag
    17401 tgagcgtcca tacattattt gtcatctcgg tattttttcc cgtgtaaatg atttttctat
    17461 atttatcgat ttggaattca taatttcccg gcgaagtatc atatccggca ggaccagctg
    17521 tttcaacgac tcgatattta ccaggtgtga gtgaatcaaa actggcaaga cctttttcat
    17581 tcgttgtttg gctgtcaatt ggctgataag taccatttgc ttcttttttc tgtagggaaa
    17641 atgctgctcc tttaagattt atctctttgt ccgtcccttg catcgcatac ttacgtactg
    17701 ctacaggaac ttcaacaaaa ggattttcaa tagtcaactg gatcgtatca tcggaagtag
    17761 tgactgtttt tccatcaatg gttaccgtac catcagaagc gatcttgatt tcccaagtag
    17821 tctttttgct taatccatgc ccttctggag cttttgtttc tgtcagcgta taggtcattt
    17881 ctttttgcaa tttgacattt tctggaagag aataggttcc gtcgccatga tctgttagta
    17941 aagtatcaat agaatctcct gttaatttga aaacagcgcc aataagatcc ttttcacctg
    18001 tagaggaatt tttcgttatt ttcaagttta acggtgtgaa ttgtttagta tttttccatg
    18061 tcattgcatc tatttgttga gaatcgtatc ctggtacagg taattctttg attgtttggt
    18121 aactgaatgc ttgaccttga ttattgtatt gaggtagtga taatatctct tgataacttt
    18181 ctccgctatt tgcagataat ttgtcaatgt ctgcacgttc ccacgtattt gttgtatctt
    18241 tagctggttt aatgattcga atatatccgt ttttccaagc tgcagcattt gtcgtatgtt
    18301 cccgttgaat ctcaaaagta acttgatctg gacgatcagc tagattgttg tcaaattctt
    18361 cccataactt tttgatgtga agactgactc cgggagcttt agcagatggt ataccgaatt
    18421 cagctaattc attggtatca atgtttggct ggaaagttgt cctgccgttc atttgatacc
    18481 agaaatttgg atggaagtcc tcattttctg tttggattct cacttggtaa tggatttgga
    18541 tttcttggtc ttttcctaaa tagatctgat tgctcttgat ggtatttcct tctatggaaa
    18601 tagatggagt gaccgttgta ggacttgtcc ccacactctt gactgaaagt gtaccaggct
    18661 gataaatgaa tggttctgcg attggatcat ttatttgtcc attgcttaca gttgctgaga
    18721 tctgtacagc ttttttggct aggtattcag agatatctgt tgcatgatca gctgattcat
    18781 agtaaagatc gcctttttca tctgatgaaa ccatttgtcg catacgagac tctacttctg
    18841 cttttgagag accagctgcc ggatcgcttt gaagttggat gccaagacca tgtatttcga
    18901 ttcctcgttc tttgagtgcc atcgcttctc cgatggttgc gataaacgta ctgtcgattc
    18961 ttctggatag attgttttgg tcaggtgcat catagattct tgagattaga gaagtatttc
    19021 ccggccgatc ttgcgtatta gaaaactgag ttccgtaata attgctgctt gattgtgcgt
    19081 gtacccgctg tactttatag gaaaatgttg gtacaccatc cgtcagcaaa acgatcactt
    19141 ttttatgtcc atttggaacg gatagcatgc ttcctgcatc tcttagtgct ttttgtgtaa
    19201 aagtaccacc atttgtccgt gaaggtgtaa tggattttac ttgatttttc actgaatcaa
    19261 atgaacccat ctgtactgca ccgttactgt agctatatcc ttcgcttgag tagccgacat
    19321 atcccatatt gattttgtct gtgataccgc tatctgctaa agtatcgaca aaacgatcga
    19381 caccaatctt tacttcaccg atccgattat tgtcgttcat acttcctgac cagtctacga
    19441 ccaatacgag atcaagaggc gtgatatctt tttgtacatt tccacgagca ttcaaataaa
    19501 catcaaacaa tccgggtgta cttgtttcct ttgcatactt tcgtatcgca tagtctgctt
    19561 gattaccggt tcctccatat tcgatatacg aatgggtccg atcattagga tctccattcc
    19621 aagaatttat accatcccat tgatttgttc cgtttttatt gccttgatga tcaagaacat
    19681 ttgtatttcc tgtaggttgc caactggctt taggataagt gccctgatca tctgttgtat
    19741 attctgtagg aatcgtttga ttagatggca cactcacagc tggcaaggat aatgtaggca
    19801 atgtaaatgg gctgacagaa ttttcgtttt cttttgatga ttcttcttct atttcgtctg
    19861 gctttggtac tgacacatct gtatctttct tattttctgt ctcatcaata atgtcatatt
    19921 ctttattatc gacgatcagc ttgtttgcct ggctgtggta aagtgctgga tcgattggaa
    19981 aactcagatc gatagtttgt ttagtgtttg atgagatttc caacgtaatt ttcccgctat
    20041 ttacctgata agcatagcca tctccttctt ttctttccac atcacttaag taattttcga
    20101 ctagaccaat ttctttttct atcttttcag cactggtgtt attcgcattt agcttgatgt
    20161 tcagtgcttt ttttccagac tgatccgaaa tgacttcagc tgaaattgtt tctaaaactg
    20221 ttggatcatc tgtagtgtct gctattgcag ataatggcac aaagtttgat aaactcaata
    20281 ttatcagcat gaaaataact ttcagtttct tccctgtggt cgtcattttt cccctccttt
    20341 ttcttttttt ctgttttgac gtgaatagtg aaaattatta aaataaacag gcgttacata
    20401 attttattta ttttaatatg ataattatta tacgaagggc gctaaaggga atcacaccaa
    20461 ttttcatacc aattggtttc atttatgaag ttgattcctt cgattaatga gcgtttcatt
    20521 gaaagaaaag ggttgaggga gaaaaacata tgatcaggtt gttggaatta aactatagaa
    20581 agatggaaaa aatcattcga attctgtcca tttctgacaa gtggatgact aaaaaagaac
    20641 ttgccaaacg aattggtagt tcagaatcta catttgtaag gtatatcgaa gagatcaaaa
    20701 tccgctgggg aacggatgta acgattcaat cttcacaaaa attggggtat cgtcttgaac
    20761 atttgaatgt accagcttat ttaaatgttc tgatggaaat gtcgcaaagt tctacaaaca
    20821 gtcgtttatt aaatgagatt attgtcaatc cgggtaaaac gattgagtat tattgtgaaa
    20881 aaatttccat cagccggtct tcttttacac gtaagttgaa acaatgcaat caaattttag
    20941 aaagctattt attaaaagtg atcgttgacc aaggttttca gttaactagc cttaaaagtg
    21001 agctccagtt gcgtatcttt gttacctttt tctttttaag ttactacgga agacgcacgt
    21061 tgccatttcc aatcgaaaaa aagaagatca aagaaattat ggtcaagaat aattgtcaga
    21121 tgaatttgtt tcaggaagaa agcccatatg agcaatcttt ctttattatg tattttgttg
    21181 tgcatctcat gagagaatcc caaggaactc catttgaatg gaaagctgga gactcttatg
    21241 tacagttgat aaatatcgat aaaaaagact tcttaatctt gaaaaatctc ttaggaaaat
    21301 tgaagtacag cagctatata aaagtagtga actattttgt caatacgatt ttttcagaat
    21361 tttcggagaa agaaaaaaat gaaatcagtg agcagatacg aaaaaatatg tcctactgtt
    21421 cgttttcatc cgctgattgc aaagaaaaaa acgaagaata tgttgttcaa ttattaacgc
    21481 aaatttattt tttctcccgt attttcccat acgatacgac tcatttgacg atccgtgcaa
    21541 cttactttgc acagcagatg caacaccgcc agatacgtct atatgctgga tttcgtgcag
    21601 aacttcaatt ttattccact ctactgaatc agaatctgat ttattattta tctagctata
    21661 tcttttggat gcttatcggt aatcctgaaa ttcaccatta tacttctgat aaaaaaatac
    21721 tgattatcag cgacttaagt cttcgacata gtcaatatat tgaagaatat atcagtgata
    21781 ttcttgctgt gcataaaatt cactctgaga caactgctat tactgaagat cagctgtcga
    21841 aatacaatct tctcgagtat gatctgatcg ttacgaatca acccattttg aatgcccatg
    21901 ttcctcatat attgattgat gatagtgtgt cattcgcaaa tgaagaagaa ctcatccgct
    21961 tattcgagtt atgaataatc aaaaaacagc tatgtataaa ccaccctgat aaaaatttca
    22021 ggacaaatac acatagctgt ttctttttat tgtattcctt cagcaatcca acgagattta
    22081 tagcgaaagt cttttaacaa ctcttctttt gtccaattat ttgcaatgag atccgtcaaa
    22141 gtgttcatta cgagggtcat ggaaaagtat aggaaactaa ctgcttcttc cgacgattga
    22201 atggagaaat gattgattct taataattcc agccattttt cgttcattgg agaatcagcc
    22261 gatagttctc tacgtttggt tgtctgctga tcatttcgct gggttaacaa gtataacctt
    22321 tgccaataga tactttcgtg atctaagtcg cagcaccact ctaaatattt ttcgatcccc
    22381 aaaaagaaat gttgtttgtt ttcgctaatg aattttaaga tatcttgatg gactatgtga
    22441 gaactgcttt tgatcgtata caaataagca tcttccaaat cttgaaaata tttataaaaa
    22501 gcaccgcgcg acatccccat cttgtcaacg atttctgaga ctttgacttg gctgatgtgc
    22561 tgtgagcaaa atatctccag taataggtca tcgattctct gtttctttgc gttcgataaa
    22621 ttgaaaaaag tttcttttgg catccacatc tctcctttat ctctgattat acgtggatag
    22681 cccttcattg tcatgaagga ttcattcctt ctttttctct tcttctgtca agtacccatc
    22741 ttccattcga taaacgcgat cactccattg aatcatacgg acatcatgag taaccataat
    22801 agtcgctttt tgtttctcat gagcttcttt aactagtaat ttgacgactt catatgcatg
    22861 atctgtatcc aaactagctg ttggttcgtc tgctaagatc aagcttggct cattatataa
    22921 agcgcgagca attgccactc tctgtctttc tccaccagaa aggtctttag gataactatt
    22981 tttaagtgac tggatatcta aagattgcag caaggaatcg atttttgttg aatcttcttt
    23041 ttttgaagta acttggtcaa ctagttcaaa ttgttccttt accgttaaaa aaggaatcaa
    23101 attagagctt tggagaataa atcctatttc tttaaagcgt aaatctgctc gttttttttc
    23161 tggaagctca gttagtgagt gaccgttgat cactatttct ccggaagtcg gtgtttgcaa
    23221 tcctcctgaa atggtaagga aagtactttt acctgaacca gaaggaccaa tgatgctgac
    23281 gaattctcct tcctttacat aaaaatcaat tgctttcaaa gctgagacct ttgtatgacc
    23341 agaaccaaat gttttggtaa cttttttcat cgttaatatt tttttcattt ttattaacct
    23401 cctattgctg taattgggtc tactttggtt atcgtacgta tcgaaaacaa tccgcctagc
    23461 attgcgacaa tgatcaaaat cccactatat agcaaccatt gtgaccaaaa aacagcaaaa
    23521 ggcatcgcgc ttggtaaaat cagactagtc aaataagcaa acaaaagagc aagcagaacg
    23581 cctaccaccc caacaataaa ggactgtgct actaaagatt tagcgatgaa gaaatttttg
    23641 atcccttgtg ctttcattac tccaaaaata gcagtcttct gaagtgtcat cacgtacatg
    23701 aaaataccga ccacggcagc aaccactaag aacaaaaagt atatcatcgc atttaaggtc
    23761 atattttggg cagaatagcc aggaatactt tcaatgaatg tcccaatagt taataactgt
    23821 agacccttcg atgctttttc tttcgaaatt ttagctgaat cctttattac gatcccattg
    23881 atcggctgtt cttcttcaga agcaaacggc tgttgtccat acttcaaagc agtccacgta
    23941 tctagggacg catagatgac gggagaaact gtgtaataag tttcaggaaa gataccgaca
    24001 atcgtcaaag gatcgtcgta actgccaatt ttgatcgtat ctccaatttt atagcctgaa
    24061 tcagccagat tttgagagat gatgatttca ttctttgttt taaattcatg ccctttcgtg
    24121 agttttggta ataaaaatgc ttctttcgtt gtgccgaaaa ctgtaacatt ttctttgttt
    24181 tttcctttga ttgctccgct gtacaatccg attggtgctt tctctcctcc ttcaatgtat
    24241 ttcagatctc ctcttgttaa ttgtgaagct gcaaatactt gatttgcatc ctccgacaaa
    24301 acaatctctt gtgcgtccca atcatcgatt gcttttttaa actcttctga aagtccattc
    24361 gctagtcctg acaacatgaa tacgacatac gcaatcaaga acataatacc gacgatcaag
    24421 ccatatcgta atttagaata gcgaatttct ttgatagcta gaaacatttg tttttcctcc
    24481 ctatgataga ttgatagtga caaaatgtca cttgttgaat agtgtaactc taaagtgaca
    24541 atttgtcact tgtgttgttt ttttcttatc aataaattgt ctaagacatc tttcgataaa
    24601 accttaacat gagtcataaa aaatttattt aagccttatt tatgctttcc atgataaact
    24661 aaagtgacca aatcaatgag gtgggaaaat gattaaacta ttagtagtag aagacgataa
    24721 agtattatcc aataatataa aagaaatact cgctgcaatc ggcgagataa cacaagttta
    24781 tgatggtagt gaaggactgt tcgagttgga aagtggagtt tatgatcttg caatcttgga
    24841 tttgatgatg ccggaaatga atggatatga agtgttagca aaaatacgga aagaaaaaat
    24901 acagactcca gtattgattt tgactgcaaa agatagtttg gaagataaga ttgaaggatt
    24961 tgaacgaggt gcagatgatt atctaacaaa acctttctat cgagaagaac tgatcatgcg
    25021 cgtgaaagca ttattgaaac gctcgctagg tctctttgat gaaaatgttc tgaagtataa
    25081 ggatatcagt tgtgatttaa aaagcaatga agtcttgtat aaagaacaag ttttgcccat
    25141 acaaggaaaa gagtttgaat tgctcgttta ttttttacaa aataagggaa tcattttgac
    25201 aaaagagcag atatttgacc ggatctgggg atttgattct gatacgacga ttacagttat
    25261 tgaagtttat atgagcaact tacgaaaaca tctgcgaagt actggattgg ataaagaaat
    25321 caaaacctta cgtaatgtcg gttatatact gcaaagggtg tgatgcaatg aatggagata
    25381 ttacacgaaa gcaacgtagt cgcttttttg cgacaaatgt agcagcattt gcttttatct
    25441 tttttctttt gggattcatt actttacaga tattaaacca atctgcatac agagaaacag
    25501 atctgtcatt agagaaaata aattttgatt ctcgaacagt acaattagag atacaaagat
    25561 atcagcaagg cgatcccttt ttaaacccga ctcaaacgga acaaaacaga acaaacatgg
    25621 aacagccatt aatggaacca tcaaatgacc gttttaacac tcaagtgatc ttgtggtcta
    25681 aaaatggtga gatattgaat aaagcagcta ttggtgggcg tttcaaccaa atcaaagaat
    25741 taaaaatgga tacgaaaaat ctgaatacca tccaaaatat tgaattaaat gaagacagtg
    25801 gctcatctgc cctctctttc cgttcgatta cgaaaaaagc ggagacgaat caagatggcg
    25861 ttgcctacat ccaaatttta gaaaatacaa atcaaatcaa gaattcatta gcgacttttc
    25921 gcacgattat gattttgtgt atgattgttt tttggattct ctctattggt atcagttatt
    25981 acttgtctag tctaagcatg cgccctatta ttctttcttg gagaagacaa aaagaatttg
    26041 ttgagaatgc ttctcatgaa ttgcgcacac cgttaacgat tattcaaaat agtttggaac
    26101 atctttttac caagcctaat catactatta ttgaagaatc cgaaagcatc gctcaagcat
    26161 tgtcagagac gaggcgcctc actggattga cttcggattt gctgacaatc gctcggaatg
    26221 attctgatca gcagctgctt tcaaagcaaa tgatcaatac acaagaatat atcgaacaac
    26281 ttgttaaacc atttcaagag atggccatca tagatggaaa agagtttatt ctccataacg
    26341 atgcaacatt agaagtacca attgatgaaa aaaaaatcca tcaagttttg gttattttgc
    26401 tggataatgc attaaaatat acgaatccag aagataagat cattttggat tcatctgtta
    26461 accataaaga atggctgatt cacgtaaaga atactggccc ttctatcagt gaagaagatc
    26521 aagcaaggat ttttgatcga ttttatcggg aagatcaatc tcgggcgaaa gagactggcg
    26581 gatacgggct tggcttggca attgcaaaac aggtaatcga acagcatcat ggacagattt
    26641 ctgtatccaa ttatcttcca caaggagtcg attttaaagt ccaattgccg ttgaagccta
    26701 aaaaataatg cttatcccta aaaaagggct gtgacaaaaa tcttgtcaca gccctttttt
    26761 gttgcgaata aacggtgttc cagaagtagc ttcttcggaa ataagccgaa atttctttaa
    26821 gctgaccact tctgtcacaa cctctttagc ttacgcttac gattttttat tgcggtcttc
    26881 aatgtgtaca tcaccgcttg tgtcaatatc caattcttct cggctaacat cttctgtcac
    26941 tttttcaaca tcttcatgtt cttctttatg aatcccaact tcttcacgaa taactgtatg
    27001 tttgcttaca tctacttgct cttctttgat tgggatagta atcgtgtcat cttccaattt
    27061 ttcgtctgtt ccctgtgaag attgatctgt tactggtttg cgttcgatga cgatttcttc
    27121 acgtttgacc ggtacttcta ccgtttcagt atcgttgacc acatgtttgt ggatgtcgac
    27181 ttctccagtt gtcacatcat gtgtatttac atctaatttt tcttctttta gttgaattgt
    27241 atcatcatct agatttggtt tgcgatcgat gtcttcagtc ttgcttgtac ccattgtatc
    27301 agtctcgcca ggtacgtcca tcggatcagt tcctggtgtc atattcaatg gatccgttgt
    27361 attttgaaag cctgtcgtgc cacctacgtc cattggatct gttccagtgc cagtttctaa
    27421 tccagtcccc attgtgcttg ctgggctaac agtatcttgt gtatccattg tatcttctgt
    27481 tgtttctggc tgacgatagc cttttactgt gatgacaaat tttccatcag aaatatctcc
    27541 tctatattga tataaaggat cattttctgg tgtagccgtc tcagaatcat aggtatcaaa
    27601 agaaaaagta tcttttattt tttcccataa agaacggtct tcttcaccat ccatccgatt
    27661 ttcatctgtt tcaacatcta taccagacaa tccgtcaaat cctagtctag atgctgcttc
    27721 atcagtagta taaataacga tatcatctcg ttcataccct tcgttacgca accgttcaat
    27781 tactgataat gcttcttccc tcgtactata gcttccgatg accgttaaat ttttctcttc
    27841 catgtaaatt cctcctagca aatagattta tgattggtat attgttactt ataaatttat
    27901 tctataggag acgattgttt tctacaaata tttagattgg aatttgatta aaacaattta
    27961 attgaaattt gaaaacattt atgttaatga aagtcatatt ctaataaaat gtcatttgtt
    28021 tctatatgaa tttttatgaa aaatttcata taatttccac tcgttgtgat ggtttaattt
    28081 atccaatcca tcaataagca aacaacttat ataaaaaagg attaattctc aatataattg
    28141 ctcctaccat agaataaatc ttcatgtaaa gtaatgaagt accaactatt tctaatactt
    28201 ctttaagaat tatcccaaca atatcgttag acaaaccatt attgaataaa tggagagcca
    28261 atcgattctg aaaaaatgtt ttctaatttt tcggaaataa aagaaagagc ctcctgccat
    28321 tagaacgaac caaatccatt tcattgctca tgaagtaacc acatagctaa aaagaggata
    28381 aatcaattaa aagatcaaaa gaatgactgc actaataaaa taactaaaaa tgtatcttct
    28441 tacttcatat cttttagcta gtacttagtt aaaaatttgc ttcctaagat caagacaaac
    28501 tgtctatctt catttgatga aatgcggtaa aatatagaaa atgaacacta ttggagggaa
    28561 tttgtaatgg acagcaaaac tagaaaacaa ctgcaagaaa agttaaagca acgtacacac
    28621 ttgctccctt ccgtctttca acagttttta gaagaaaatc gttcttccct ttcattaggc
    28681 agtcgctatg aatacgcaaa agattttcat ctgtttactg attatttgag aaaagtattt
    28741 tctgaagaag tggatgatca gctgattatc catttagaaa aacaagatta tcagaatttc
    28801 ttagctaaaa tctatcgaca tactcgttcg ttccaaacta cagcgaacca agaaacggag
    28861 caattgtttg aaaatagcta ttacgggatt tcaaggaagc aatattcatt aaatcatttt
    28921 ttacgatttt tgtatcaaaa aggactgatt gaagaagaga tttctctttt gggtacaagt
    28981 ttaccggaaa caaccaaagc agctccgcga tatatcgatg cagaactttt caaagatttt
    29041 gagcatttgt ttatcccgat tgaaggcttt caaacaagca gagaagctag ctttgaagaa
    29101 aagaatagac cgaggaacct tgcaattact gccattcttc tgtattgcgg attaaagatc
    29161 catgaagtag tagaacttaa acgtaaagat gtatctttga ccaagcagat tcttaatctg
    29221 aatagaaaag aaaacagact gaataaagta ccaataccaa aagaagcgat gccatttctg
    29281 gagaactatt ttaagttaac agcacaaaat acggacgaaa attcttttgt ttttcgttcc
    29341 tcacatgatc agcaaatttc tcctcggact attcgccaaa ttttgagcaa aattacagta
    29401 tataaaaacg tatcgccaga actatgcaga aaaacatatc gttattatgc agaactatat
    29461 ttagatgatg ctgacgcggt aaattattta tgtggtaatc gatacctctc atcccattct
    29521 tttcaagata tctgggaaaa gatggttgat ttttcttatc acgaattagc ggcattcgtt
    29581 cgggtttctt ccatataaaa caaatgtatg atcttttttt cacaataaac tatgttatta
    29641 tataaaggat tatgttacga ttatcttgaa tttgtatatt acttaacaaa agataatgga
    29701 gtgtgaatga tggagaccat aacgtattcc cctttgaact tatttacgaa ttttcaagaa
    29761 gctgcagcta acttttccga gaccccgatt atctttgatg agccactttc agctttccca
    29821 gaattaggac ttgaaacaac ttacaaaaaa tgctgcgaaa gtgtgttgaa acgggcttat
    29881 caattggctc atcttggagt gaaatccgga gacaaagtta ttatttataa gagttccgct
    29941 tttgacacat accttctagc tgtttctgtg tcttaccttg gtgcagtgcc tgtcatgact
    30001 tcttatcatc taccaacaac aacaatggaa gtatttatcg atcgtttaga agaccctttc
    30061 attttatttg atgatgagac aaaaaagcga gtgagagaaa tttcaaatgg aacaaaatca
    30121 aaacagattc ctattcttta tttaatggaa caacctgctt tgtctgtttc tcaatcattt
    30181 ttagacaaaa atgaaatttc ttatatgacc catacttctg gtacaactgg tatccctaaa
    30241 cttatttgtc attctgctca ttctatggga tggcggacga aatggcaaaa aacagttttc
    30301 acaaaaattt cggaaaagaa attaatcgct tttcacatct ctccagtgca ttccagattc
    30361 aatattggta tctcttcttt gatgtccatg ggatttccta tgatgccttt agcaaacgca
    30421 caaagttcaa aagttgttca tatgttggaa gctcaccggc caattgcact agagacccat
    30481 ccgaataact ttgttcagtg gcgttttact gctaaggagc atccagaagc tttttcgggt
    30541 atccgatact atcactccac ttttgatgct ataaacaacc agacaatgaa gacatttttg
    30601 cgaacgtcga tggcacagga tgcggtattt cttcaagtat atggccaaag tgaatgcgga
    30661 ccaatgattc ttaaggctca tacactagag agtttgaaaa caagtgatgc aagagatatg
    30721 ggcgttggac tggaagacat gacaagcgct cggattacag attcagttgg gaatgtccta
    30781 cctgaaaaca cagatggtca tatacaatta ctgtctaaag gacgggcttt gacttattac
    30841 aaggaagatg cacggttcca ggaaaatgtt tatggcgatt ggtgggatag cggagattac
    30901 ggttttatgg ataagcatgg ccacctattt ttgaaagatc ggcaagtgga tttgatcgaa
    30961 acgatcaata gtacattagc tattgaagac tttttattag attcgttaga ttttttggca
    31021 gaagtagtga ttgtaaggga taaaaatcat tctccacaac cgattattgc tttagctcct
    31081 gataaagaaa tggattggaa tcgatggtgg gagcaagtcc atgaacttcc tcgcttgaac
    31141 gtccctatca tccgtgattt tgatgcaatc ccgcgaacag ctacaatgaa agtgcaacgg
    31201 cttcaaatcg agaaagaatt aaaatcacaa aagtcctaac tatttaagga aagaaagatc
    31261 cattttggtc tttcttttct ttttgttttt ttaaattgga tgagataaaa atatgccaat
    31321 tggctgtttt tcttttttga aaatttcgtt atactcttat tcatggagga aaatgttatg
    31381 aaaagaatct tgacaattgg cggttctgat ccatttgctg gtggaggaat ccaaacagat
    31441 ttaaaaactt ttgagaattt tggtctattc ggactaagcg ccttgacttc tataggggca
    31501 ctagatatta atgagcgatt tatgctggaa tctatatctt tggaattgct taaacgacag
    31561 ttagtttcga ttgataaaat gacttcatta gatggtatca aaattgggtt attgaattca
    31621 agtgaagcaa tcatggttgt tcgagacttc ataaaaacaa aacaaaatat cccaatcatt
    31681 ttagaccctg ttttggcatt caaagaaact gaagctgtga tcaatcaatt gtatatttcg
    31741 cagctcatcg aagaactttt tccacttgtt acgatgatta cgcctaattt ggcagaagct
    31801 gctttacttt ctggtcaagc tcttccctct tcgttaacag aaatgatcca tctcgctaaa
    31861 gaactcactg cttcaggaac aaaaaacatt gtgatcaaag gcggcacaag gatggctgga
    31921 gatgaagctg tggatcttct ctattcaatt gatcattatg aggtattttc tcataaaaaa
    31981 atcgacacta caacagtaaa cggggccggt tgtgcctttt cttctgcaat aacagcgaat
    32041 cttgtgttag gggcagattt taccaaagca gtagcagaaa gtaaaaaatt tgttgcccat
    32101 tgtatttcta atggcgtgct gatgaacgat cataccggaa gtgtctggtc tggcggtatt
    32161 caaaaaggag gaatgagaaa tgaaaactaa gcaattaacg atctatgcta tgctgattgc
    32221 gttgacagtt gccctttcat taacaatttt gatccctgta ccggctacga atggatttgt
    32281 gacattatgc gaggccggga tctataccgc tgcttttctt tatggtccaa cgggtggatt
    32341 agttgttggt gcttccagtg gtctattgat cgatttgatt tcaggatatc cgcagtgggc
    32401 agttttttca ttagtgatcc acgggttaca aggatatgtt gctggttctt tcagcaaatc
    32461 ttctactcgt atgtggggat tagggctttt attaggaagc ttagttatga tcatcggcta
    32521 tggtatcgcc ggttggattt tatatgattg gccggctgga gtggcttcta taccaggaaa
    32581 catcttccaa aatctgattg gaatgggact tgcctttcct ataactgcaa gtcttcaacg
    32641 tattcaagca cggaagcaat attaattgaa aaagaaggtt ttagaaaatg aagttgtcag
    32701 aaaaagaatt aaaagaccaa ttgactgaaa tagttaatga catattggct gaggcacact
    32761 tgaaaaaagg tgatcttttt gttttaggat gcagcacaag cgaagtcgtt ggaggacata
    32821 ttggaaaaaa ttccagtgcg gaagttggtc aatggatcat ccgtacgtta aaagagttgt
    32881 tggatcctaa agaaattgcg ctagctgtcc aaggttgtga acatttgaac cgagcattag
    32941 tagtagaacg aacagtggca gaagcaaaaa atttcgaaat tgtctctgtt gttcctgcac
    33001 tacatgctgg aggtgcttgt tctgttgctg cttttgacca gttcaatgat cctgtcgaag
    33061 tggaacacgt agttggacaa gccggtatcg atatcggtga cacatcaatc ggtatgcata
    33121 tcaagcatgt ccaagtacct gtcagacctc gtttgaaaac ccttggacaa gctcacgtga
    33181 cagcccttcg ctctcgtcct aaatatatcg gtggtcctag agcgaattat tgaaatgagt
    33241 aattgacaga gcaatctgaa aaacttcctc gcaaagtcca actaatgaac tttaacgagg
    33301 aagttttact tgtttgtttt atataaccga gcttcataag gtgctagtat gcctttagct
    33361 tcaaattctc cgctagagga atttgacaag agtaatgtcc aggactgatc tgcttctttt
    33421 ggaagttcat agtcagcaag tgattctgtt aagtttacca taataagata ttgttcatct
    33481 tctaaatatc tttcatagac ataaagttgt ggatgttcat gaagatattc tttataagaa
    33541 ccgtatatca gacctttatt ggtttgtcta atgcggatca tgttcttata gaattgcagg
    33601 accgactctg gttcatattc ttgttgttct acattgatcg ttttggtatt tggattagtg
    33661 atcagccaag gttcatgtgt agaaaaacca gcatattgtt ccgaagtcca ttgcatgggt
    33721 gtcctgctgt tgtctctcgt tgtttcacga atgatatcca atgcttcttc tcttgtctta
    33781 ccttccgcaa gcagcctttt ataaagtctt ttcgaatcta ctgcatcaac ttgatcgatc
    33841 gattcaaagg gcatattcgt cattccgatt tcctgtcctt gataaataaa tggcgtacct
    33901 tgcaaaaaga aatacatcat agcgattgct tttgcagaca tagcccaaaa atcgggacga
    33961 gtatctccaa acactgaaac ggcacgagga acatcatggt tttccatata taaagcgttc
    34021 catccgatac catccaatga agtttgccaa gcgcttaatg catgtttcaa tttaaggaca
    34081 tctaattgcc cttctttttc ttgctgccag atatggatat gatcaaattc gaatatcata
    34141 tcgaaataac cgtctttccc tacccattgt ggtccttctt ctgcagtgac accacttgct
    34201 tctccgacag tcatgatatc gtactcttca aaaacatgtt tcaaatcggt caaatgttct
    34261 tcgattcctg agacattttg aaagggtgag aaagggttct ctgtggcttt tactgaatat
    34321 tcatcttttt ttacatgaga aatcgcatct aaacgaaatc catctatccc tttatccaac
    34381 caccatcgga tcatattgaa tagttcttct ttcaatttct cgctttccca atttaagtct
    34441 ggttgttctt ttgcaaaaac atgcagataa tactgtccag tttcatgaga atactcccaa
    34501 gcagaaccgc cgaaaatcga tgtccaatta ttcggttctt tgccatctac cccgtcgacc
    34561 caaatgtaat aatcgcgata cgggctttct ttagattttt tcgattcttc aaaccattga
    34621 tgctgatccg aactatggtt gatgacaaga tccataatca ctttgatccc taattcatgt
    34681 gcttctttta gcaataaatc aaaatcttcc atcgttccga atctctcttc tatatcttga
    34741 tagtcactta cgtcataacc attatcgaca aatggagatt gatagatcgg attgatccag
    34801 ataaagccga taccaagatc tttcaaataa ttaagttttt cacggatccc attgatgtct
    34861 ccttgaccat cgccattgct atctttgaaa ctagcaggat agatttgata gcctactgct
    34921 tctttccacc atttttgttc ttgtatcata tcgtttcact cctttaacgg tccctcttga
    34981 ttataaccga ttctatttta gaagtatcct tgttaccggt aactagaaac gaaaagctca
    35041 acgaatctgc taagtgcgtt cgttgagctt tattttatca tagatagcgg gcaatcagtt
    35101 gaatcatttg cttgggaaat tcattcaagt cagtaatatc tacaaaacga ctttcaccgt
    35161 agatcgactt gatttcttct ttgtcttggc caatagctgc ggagacaaat aggattcctt
    35221 gacgttcata ttctttcaaa acagactgga tatcttcttt tgcttttttg cctgtataat
    35281 ccggcaacgc ttttggctga ccgtcactaa tattaagcaa cagtttggtt gttgcggatt
    35341 gtctgtttaa tttttctgct gctaaacgaa gtgcagcacc atcacgattg ttttgccttg
    35401 gtttcatagt gactaatttt tcatttaacc attgaaatcc gtcttcaaat tctttataag
    35461 aaaacaaaga agtcttttct cttgacgaac ggtctgctgt atctccgtaa atcaacaatg
    35521 ggatatcgac tttcttagaa aattcggcaa tggcaatcgc tgcttttttt gccgcttcga
    35581 tccgatcatc ccgtatcatt gacccagatt catcgatccg tacagctacc gctaaagaag
    35641 gttgctcatg tggcgggttc tttttgtcaa aatttctcaa atcaccatat gctactttgc
    35701 ttgcattgaa ccgctgacct tcgtattttc ctttttggta cgtctctgtt tgttcattat
    35761 ccagtaactc taaaatttgc cggctaagtg attctactat tggcattact tgcatgtgta
    35821 gctcacgtgc ttccggcgtt tttccttgga aagctggtcg gtgaacgatg agaccttctt
    35881 tttcatgaat cgtttccttc atgatttgtc gcgcttcttt attcagttgc ttcttgattt
    35941 ccttatcatg tgcttccatg tcagaagcag acatttcttg agaatcatct cctgtttgtt
    36001 gttctttttg attttttcct tcgatatcgc tactgcgttc tttttgcatt tgaggaggaa
    36061 tctcgttttt ttctattgtt tcttcttgtt tctcttctcc ctcatttggt tcttcagcag
    36121 acaacgattt cttttcatct aagcgcagaa tttcttcagc attttcagtg atgtttcgtt
    36181 catttgcttc ttcggcgcta atggttcttt cttttgtatg ctcagattga ggatgacccc
    36241 atttttcttt tctcaatatg tcctgaagtt ccagtagcaa tccactgtca gacaaagctt
    36301 gttcaagaat tgccaattca tctgaatcag tggataattt atacaaaact tttggataaa
    36361 tcgactggag taaatcttgt ccttgcttat aggtatttgc ccaataaaaa taagaacgca
    36421 ttcctgctac acctttgatg gcgttagctt ttgcagtttc atccaacaaa cggataatct
    36481 ctgccatctt taagagaagt tcttgttttt ggatcatagt tttcgccatc gcacgttctg
    36541 ccatgacttc taaggcagga agatccattt tttccgcatg ttgcatccga tctcttaaag
    36601 attcatttaa tgggcgattt ccttggtaat ttcgatttgt agtgatcaca atgacgcaat
    36661 ctggatggcg acgaatgatt cctgtcggta aattcaacat cccatttggt tcgagcgctg
    36721 agttaagtgc cacaagaaca gaggcatctc ggatgacagt cggctcttga atctctaata
    36781 aatagccttt ttcaatcgct cgaacgattt cagaagggta atagctgtaa tggattgcat
    36841 ctggataatc agcttcgatc ctttgaacta gctctgctaa tttttcttta gcagaaaaag
    36901 gatcaatgcc gtaatggttc tggatcagtg tcagtacagc ttcaagtgta tctgtttggt
    36961 aaatagcttc tagtaattct tggtcttgtt ccttattaga atctactaca ggtaataagg
    37021 ctccgaaaac atctgatttg tccatatctg caaaacaggt cacttttgta tagggaagtt
    37081 gcagatcagc agatagtgct ttggctaatt gtgtcttccc cgacccggca tctccttcca
    37141 aaagtacgtt actgattttc atttcaggat cttgccaatt ccctttgatt tcggaggcga
    37201 tccgccattc ttctgcactt gtccgatggc ttttcggttt cttccagatc atttgctttt
    37261 ctagccgtga aaaggttcgg ttttctgtta gtgagaaatt ctccatgctt ctcttcccct
    37321 tttgatcatc tctgtctatt aatatcctag ctcatctaaa agacgtttta aaatacggaa
    37381 tcgttcccca atcagttctc cgtctttttg tagtgtatcg taatacaaaa tgatgtcttc
    37441 atcgatcttt ggatttttgg tatctacttc taccgtcatt cggttccctt gtaatccaat
    37501 gatgtctacg actggatttt ctggatcata aaatttttca taacgataag catcttggaa
    37561 gtataaactt ccttgcgcag ctaagatcgc taaatctaaa atacgtgtga ttggtaattc
    37621 ttccgactgt cgtgaccatt tttctccagt atgtcgccat accttgcctg agatatcgac
    37681 ttttccacga tcattccact gagcaaggcc cagtgaaagc ccttttgcat ccatatttaa
    37741 tgcatttctt ccatcaactt tatcatagtc ttctacaacg attactggtt tatgttttaa
    37801 atttgttggt atttccatta ttttaactcc tcatcctttt atttttagta aataagtaaa
    37861 ttagtagttt actcatttac taaactatat gcgacattat agaggattga agtgaggatt
    37921 gcaaagaaaa agagcttcat tgatagaaat aaaaacacca tctcgttctt ttacacgctc
    37981 attagtaaca tgtagaaagt ccaagatgat gttggaatat tttggctcta tactttttga
    38041 tgttggtgaa cttcaccaac atcttttttg tattcttaat tgtcaaatta agttagacag
    38101 atcatca
//
LOCUS       DAIGWC010000019        36569 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.019, whole genome shotgun sequence.
ACCESSION   DAIGWC010000019 DAIGWC010000000
VERSION     DAIGWC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.019"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="NOB74_001001"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="NOB74_001001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HCI1220203.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="NOB74_001002"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="NOB74_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HCI1220204.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="NOB74_001003"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="NOB74_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HCI1220205.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="NOB74_001004"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="NOB74_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HCI1220206.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="NOB74_001005"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="NOB74_001005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HCI1220207.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="NOB74_001006"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="NOB74_001006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HCI1220208.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="NOB74_001007"
     CDS             complement(8053..8523)
                     /locus_tag="NOB74_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HCI1220209.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="NOB74_001008"
     CDS             complement(8569..8994)
                     /locus_tag="NOB74_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HCI1220210.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="NOB74_001009"
     CDS             complement(9061..9330)
                     /locus_tag="NOB74_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HCI1220211.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="NOB74_001010"
     CDS             complement(9341..10936)
                     /locus_tag="NOB74_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI1220212.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="NOB74_001011"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="NOB74_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HCI1220213.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="NOB74_001012"
     CDS             complement(14489..15049)
                     /locus_tag="NOB74_001012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCI1220214.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="NOB74_001013"
     CDS             15402..16376
                     /locus_tag="NOB74_001013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCI1220215.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="NOB74_001014"
     CDS             16546..17946
                     /locus_tag="NOB74_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HCI1220216.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="NOB74_001015"
     CDS             complement(18024..18746)
                     /locus_tag="NOB74_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1220217.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="NOB74_001016"
     CDS             complement(18825..19331)
                     /locus_tag="NOB74_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCI1220218.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="NOB74_001017"
     CDS             19454..21253
                     /locus_tag="NOB74_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HCI1220219.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="NOB74_001018"
     CDS             complement(21321..22895)
                     /locus_tag="NOB74_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI1220220.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="NOB74_001019"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="NOB74_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HCI1220221.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="NOB74_001020"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="NOB74_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HCI1220222.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="NOB74_001021"
     CDS             complement(24672..25310)
                     /locus_tag="NOB74_001021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HCI1220223.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="NOB74_001022"
     CDS             complement(25311..25961)
                     /locus_tag="NOB74_001022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCI1220224.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="NOB74_001023"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="NOB74_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HCI1220225.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="NOB74_001024"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="NOB74_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HCI1220226.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="NOB74_001025"
     CDS             complement(29104..29844)
                     /locus_tag="NOB74_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HCI1220227.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="NOB74_001026"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="NOB74_001026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HCI1220228.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="NOB74_001027"
     CDS             complement(31215..32153)
                     /locus_tag="NOB74_001027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HCI1220229.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="NOB74_001028"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="NOB74_001028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCI1220230.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="NOB74_001029"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="NOB74_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HCI1220231.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="NOB74_001030"
     CDS             complement(35313..35618)
                     /locus_tag="NOB74_001030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI1220232.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="NOB74_001031"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="NOB74_001031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HCI1220233.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7990 c         6705 g        11988 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgc gttctgaatt ctctacaatc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatcg cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gcaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ccagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttcgtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc taattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gatatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatac
//
LOCUS       DAIGWC010000020        35542 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.020, whole genome shotgun sequence.
ACCESSION   DAIGWC010000020 DAIGWC010000000
VERSION     DAIGWC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.020"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..613)
                     /locus_tag="NOB74_001032"
     CDS             complement(<1..613)
                     /locus_tag="NOB74_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HCI1220234.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFL"
     gene            886..3357
                     /locus_tag="NOB74_001033"
     CDS             886..3357
                     /locus_tag="NOB74_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI1220235.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3460..5196)
                     /locus_tag="NOB74_001034"
     CDS             complement(3460..5196)
                     /locus_tag="NOB74_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HCI1220236.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5193..5897)
                     /locus_tag="NOB74_001035"
     CDS             complement(5193..5897)
                     /locus_tag="NOB74_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1220237.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            6028..6531
                     /locus_tag="NOB74_001036"
     CDS             6028..6531
                     /locus_tag="NOB74_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HCI1220238.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6491..6829
                     /locus_tag="NOB74_001037"
     CDS             6491..6829
                     /locus_tag="NOB74_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HCI1220239.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6850..8268
                     /gene="ffh"
                     /locus_tag="NOB74_001038"
     CDS             6850..8268
                     /gene="ffh"
                     /locus_tag="NOB74_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HCI1220240.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8380..8958
                     /locus_tag="NOB74_001039"
     CDS             8380..8958
                     /locus_tag="NOB74_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HCI1220241.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8962..9483
                     /locus_tag="NOB74_001040"
     CDS             8962..9483
                     /locus_tag="NOB74_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI1220242.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9562..10116)
                     /locus_tag="NOB74_001041"
     CDS             complement(9562..10116)
                     /locus_tag="NOB74_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCI1220243.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10369..10644
                     /gene="rpsP"
                     /locus_tag="NOB74_001042"
     CDS             10369..10644
                     /gene="rpsP"
                     /locus_tag="NOB74_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HCI1220244.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10656..10907
                     /locus_tag="NOB74_001043"
     CDS             10656..10907
                     /locus_tag="NOB74_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HCI1220245.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            11032..11823
                     /locus_tag="NOB74_001044"
     CDS             11032..11823
                     /locus_tag="NOB74_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220246.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11993..12514
                     /gene="rimM"
                     /locus_tag="NOB74_001045"
     CDS             11993..12514
                     /gene="rimM"
                     /locus_tag="NOB74_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HCI1220247.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12504..13265
                     /gene="trmD"
                     /locus_tag="NOB74_001046"
     CDS             12504..13265
                     /gene="trmD"
                     /locus_tag="NOB74_001046"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HCI1220248.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13401..13748
                     /gene="rplS"
                     /locus_tag="NOB74_001047"
     CDS             13401..13748
                     /gene="rplS"
                     /locus_tag="NOB74_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HCI1220249.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            14121..14783
                     /locus_tag="NOB74_001048"
     CDS             14121..14783
                     /locus_tag="NOB74_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220250.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14862..18089
                     /gene="fss3"
                     /locus_tag="NOB74_001049"
     CDS             14862..18089
                     /gene="fss3"
                     /locus_tag="NOB74_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HCI1220251.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            18203..18517
                     /locus_tag="NOB74_001050"
     CDS             18203..18517
                     /locus_tag="NOB74_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI1220252.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            18530..18904
                     /locus_tag="NOB74_001051"
     CDS             18530..18904
                     /locus_tag="NOB74_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI1220253.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18914..19258
                     /locus_tag="NOB74_001052"
     CDS             18914..19258
                     /locus_tag="NOB74_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HCI1220254.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            19329..20474
                     /locus_tag="NOB74_001053"
     CDS             19329..20474
                     /locus_tag="NOB74_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCI1220255.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQCATCF"
     gene            21189..23048
                     /gene="ltrA"
                     /locus_tag="NOB74_001054"
     CDS             21189..23048
                     /gene="ltrA"
                     /locus_tag="NOB74_001054"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI1220256.1"
                     /translation="MNKVKTNKTLRHSEYYGMTQIFDELYVKSDKKEVFTELMTIIMS
                     DENIRLAYRNIKNNKGSYTASTDKKSIRDIKTLSEDTFLTEVKVLFRCYKPRAVRRVE
                     IPKPNGKTRPLGIPSIWDRLIQQCILQVLEPICEAKFHNYSYGFRPNRSTHHAIATCN
                     RLANRGKLHFVVDVDIKGFFDNVNHSKLLRQMWTIGIRDKWLLGIIRSMLNAPIVLPT
                     GKVEHPKKGVPQGGVLSPLLSNIILNELDWWVASQWQNTTIETEKIMDRRDKGKGIDK
                     TNQYRALRRTNLKEIYIVRYADDFKIFCRKRSHADKIFHATKMWLKERLSLEISEEKS
                     KIVNLKKGKSEYLGFELKLIKKGKKYVVESHMSKKSMTRVKIQLKKQLRKVARPKNHC
                     EQAKEIGLYNSMVIGIHQYYGIATCVNLDCSKIAYTLKPFINHKLPTKKHGKILNTFI
                     KSKYGKSKEMRWLNNVPIVPLNYVQFRLAVPLSEGTCKYTESGRSKIHSKLKLDLALL
                     LHMMRNSNYERSIEFVDNRISKYSAQKGKCAITGKFLEYEEIHCHHIVPVKQQGTDKY
                     SNLIIIHKNVHALVHAIEEKIIHKYLNVLNLTNEQIEKLNELRVKAGNSVLTV"
     gene            23142..23393
                     /locus_tag="NOB74_001055"
     CDS             23142..23393
                     /locus_tag="NOB74_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HCI1220257.1"
                     /translation="MTSKDYLSLFNFRVALGRMSELGYSMMFGEVDKKFFMKRIKGRG
                     YVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG"
     gene            23453..24595
                     /locus_tag="NOB74_001056"
     CDS             23453..24595
                     /locus_tag="NOB74_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HCI1220258.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            24620..24874
                     /locus_tag="NOB74_001057"
     CDS             24620..24874
                     /locus_tag="NOB74_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220259.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            25130..26314
                     /locus_tag="NOB74_001058"
     CDS             25130..26314
                     /locus_tag="NOB74_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCI1220260.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            26311..26424
                     /locus_tag="NOB74_001059"
     CDS             26311..26424
                     /locus_tag="NOB74_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HCI1220261.1"
                     /translation="MKRGILMEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
     gene            27194..29104
                     /gene="ltrA"
                     /locus_tag="NOB74_001060"
     CDS             27194..29104
                     /gene="ltrA"
                     /locus_tag="NOB74_001060"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI1220262.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            29208..29432
                     /locus_tag="NOB74_001061"
     CDS             29208..29432
                     /locus_tag="NOB74_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220263.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            29445..29945
                     /locus_tag="NOB74_001062"
     CDS             29445..29945
                     /locus_tag="NOB74_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCI1220264.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            30042..31889
                     /locus_tag="NOB74_001063"
     CDS             30042..31889
                     /locus_tag="NOB74_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HCI1220265.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            31892..32788
                     /locus_tag="NOB74_001064"
     CDS             31892..32788
                     /locus_tag="NOB74_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1220266.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            32838..33227
                     /locus_tag="NOB74_001065"
     CDS             32838..33227
                     /locus_tag="NOB74_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI1220267.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            33214..>35542
                     /locus_tag="NOB74_001066"
     CDS             33214..>35542
                     /locus_tag="NOB74_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI1220268.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT        12121 a         6031 c         7529 g         9861 t
ORIGIN      
        1 gcaggaagta ttgagttagt ttgtaaagtc tgcgatcttc aaggatcgta aatagctgat
       61 gggttgtccc atcaacacaa ataaaactca tggaaccaga aacagacttc attgatttga
      121 actcatccat acacaacacc gtcggaagga agttcatacg tgactggtaa tgcttcgttg
      181 cttcacgcaa gatccgtgtc accgtcccat ccgagacgaa gtacttctta gcgattagtt
      241 tacgtgattg attttcgtac agttccatga gaattgcctg cttcagttcc tttgttagtt
      301 gatgatgttc atcaactaag tccgttttcg cagaaaaggt ccttccacaa tcatggcaga
      361 gaaaacgggt acgttttaat tctaaaatag ttaacttttc tttgactttc aatatctgag
      421 tgcgtgtcgt ataggaaccg ttgcggataa tacgaaccga tcgacagtgt tcacaatagg
      481 aaggagagtc atccaatttt cctttaataa actgcgcttg aacgccttta tattcttttt
      541 caatcagcca ttcttcatca aaaaataaat gtttatctgt taatccgagt aattttctag
      601 tatgattatc cattgagaga ctcctttggt aggatgacgt tttggtcgac taaattttac
      661 caaaagtgag tctctttttg agttgaaacg aagaaaaagt gttagtagaa aatcgccttc
      721 gattttccac caacacaaaa tattatagaa cccttttttt ttgctatatg acaggaatga
      781 aaggtgtttg caagcttaat gtgaggaaca ctttccatat ctgttctata ctggatagga
      841 gaagtttgga aatatccaga aaacgaaatc aatcgaggta gccacatgaa gaataaatgg
      901 ataaatcgaa gtaaaaaaaa gaaagtaaca caaagatcat cagataaagt catccgtctt
      961 tttccatcgt ataaagaagg attaacggca gatcaagtca aggaacgaat agaaaaaggt
     1021 gcagcaaata attcagtcga tcccacattc aaaacaaatc agcaaatcgt attggaaaac
     1081 atatttacgt atttcaattt gatctttctt atcttagcca ttttgctttg tttagtagaa
     1141 tcctataaga acttgacttt tttaccagtt atcatagcca atacaggaat cgccattttt
     1201 caggaaattc gatccaaaaa gatcttggac gaactaaatg ttttaaatac agcaaaagtc
     1261 aatgtcatac gagacgggat agaacaaaca atagatatag aagaccttgt aatagatgac
     1321 attgttattt tagagactgg atatcaaatt ccagcagatg cagaggtcgt ggaagggaaa
     1381 ctgcaagtta atgaggcttt attgacaggc gaagcagatg aaataaccaa agaaataggt
     1441 gatccattaa tgtccggcag tttcattgtt tccggaaaag cttacgcccg attagacaaa
     1501 gttggagcag attcgtatat ttcccagctg acagtcaaag ccaagacaat gggagaagga
     1561 gaacagtcgg agatgattgc ttctcttaat caattgatca aatggattgg gatcatcatt
     1621 attcctatcg gtatcctgct tttttctcaa agttactttt ttaatggaaa cacgatcaaa
     1681 gaaagtgtcg ttgcaatgga agcagcattg atcggtatga tacctgaagg actgtacttg
     1741 ctgacgacga ttgcattagc attaagtgcg actaaactag caaagcaaag agttctttta
     1801 cacaatatga aaagcattga gacattggca agggtaaatg tcctttgtgt agataaaaca
     1861 ggaacgatca cagaaaataa aatgtctgtt caaaaaatga tcgtctctaa aaaacaagaa
     1921 ataatcagtc agtcagatca attggaagca tgcattgctg actatgcaaa agcgatggca
     1981 ggagacaatg caacaatgga agctgttaaa gcatatttta caaaaaccac tgatcaatcc
     2041 tatcaccatg ttattccttt ttcttctgtc caaaaattca gcagtgtagc gttggcagac
     2101 aaggtgtatg ttttaggagc gcccgaaatg gttttgcgcg atcaattgcc ggaatatgcg
     2161 gaagagtttg tttctttcgc tgaaaaaggc tatcgcgtgt tggtctttgg tgtgtacgat
     2221 gggattcttg aagaaccagt attgacagaa gcagtcacac cattaggcta tattctgatt
     2281 gctaatccta tcagaaaaga agcaagagcc acatttgatt acttcaaaaa acagcaagta
     2341 gccatcaaag tgatttctgg agataatccg ctcaccgtat ccaatgtagc tgtccaagca
     2401 gggatttcac atgctgatca gtacgttgat gcatctaaat tatcagaaga agaatatgaa
     2461 gcagctgtcg aaaaatatac agtttttgga cgcgtcaagc cagaacaaaa gaaaatcttc
     2521 gttcaattga taaagcgtaa caatacagta gctatgacag gtgatggcgt gaatgatatt
     2581 ctagccatga aagaagcaga ctgcagtata gcgatggctt ccggaaatga agccgccatg
     2641 caggcctcac aagtggtctt acttgattct gacttttcac gcatgccaga agttgttgca
     2701 gaaggacggc gcgttgtgaa caatattgag cgatcagcca gcttgttttt agtgaagaat
     2761 attttctcct ttttgctctc actgttttca gtgatctttg ctctgaccta tcctttagaa
     2821 ccatcacaaa tcacattgat tagtttgttt actatcggac ttccatcttt cttgcttgct
     2881 ctagaagaaa acaaaaagcg aatcagaggg aaattcatca tgaatgtgat ggaaaaagct
     2941 gtgccaggtg gactaacaga tatgatcgta gtcggtgcgt tggtgatctg cggggtgact
     3001 ttgaatctaa ataaaacaga tgtttctaca gcatctacca tgcttttgat tgcagtaggg
     3061 ttcctcgttc tctataaaat ctgttcaccg ctgaataaat tcagaagtca gatcattctt
     3121 ttctgtgcta gcggtaactt tttttcggtc atctttttgc ataagctgtt ttcaatcacc
     3181 ggtatctcag ctgtatcact tttgctgttg agcattctat ttttctcggc agattcgatt
     3241 tttaggcatt tgaccacatt ggtagaatat ttgtttgaac gtaaaaatga aaaagagcaa
     3301 aagccgttta gtcgcgtagc taaaaaattt ctatcgatat ttaaacgaga aaattgacga
     3361 aaagtatctc aaaaaagagt aaaaaagaac aaccactcgt gtatctttcg aagcaggatg
     3421 agtcatccaa ctttaaaacg cacgagcagt tgctcttttt tacattttcg gaatggtaac
     3481 ggtgaaagtc gaacctgttc caagatgact gtctacagta atcgtaccat taaggagttg
     3541 cacgtagtct tttacaatcg ctaaccctaa tccggtcccg cctgaatgtc ggcttcgcgc
     3601 cttgtctacg cggtaaaaac gctcaaagat ccgttcctga tcctcaatgt cgatacctat
     3661 accaaagtct tggacagaaa acgatagatc atctgttgcc tgatagcgga taataatctc
     3721 gctgtcgctt tttgaatatt ggacagcatt ttcaatcaga tttttgataa ttggataaag
     3781 gatatctgtt ttagtagtaa atggttcgtt ctttccaatc aatcgaatcg tcaaccgttt
     3841 cttttcgatg attggctgat aattttgaac gatttgctgg aaataaggtt ctgtataaat
     3901 tgtctggatc tcgtaagaat tctcgccatc ttttgacagc tggatgattt cccgaatcag
     3961 tttatctaac cggatcgcat ctttttgcat gatctcaaga aaagaagtca gagtttgcgg
     4021 gtcatctttt gcaccatcca gtaaagtctc ggtaaaacca atcagtgaag tcacaggagt
     4081 ttttaattcg tgagagacgt tgccaacgaa atccttttgt agcttttcta aacgtcgcac
     4141 tttcgttaag tcatacgcca cccctagaat ctgtccggta ccttctgaat tagtaaagta
     4201 gcgcaaactc aagtctaatg tctgccgacc ttctgtaagg gtgatctcct gatggatcag
     4261 cggatgctca ggagtcactt gatgaatcag ctgaatgagt tttggctctt gaatgacttc
     4321 tgtgtaccgc tgttcaggtt gatagcttac cacgtttaaa tgtagctgca tctttggatt
     4381 aagcagtagt aaacgagaat cagcatcatc aatcaggaat acgccaatca tcagttcgtt
     4441 cagtaacgta tataattgct cttctgtggt agtacacgcc cgatacatct tactcatttg
     4501 ttcgctcaac gcattaatcg tctgatacaa ttcttcccat tgatcgggtg tttgcatgat
     4561 tacttccgcc tgattaggat tttgcaccat tttttttagt acgggcagca cggttttcaa
     4621 tggctggttt ttttgataga tcagataata gatcattcct gcaagaacaa ggaagaaaga
     4681 cagaaagaag aaaaagaccc aacggcgaaa actctcagtt ctcggtaaaa aaacgcttgt
     4741 cggttctgcg atacgtaaaa tggcttctaa ctggccactt tttttgactg gtaatgcgac
     4801 atataaaaga tcctcattca aagtagtact tttgcgcaaa gcgctaccta ggttcccacc
     4861 attcaatacg gctttgattt cgggacggga gtttcgctgt tcattcaatg tttcattgtt
     4921 tgtgtcaaat aagatctttc cagtagcatc cattaaagta atccgttcgt tcgactgatg
     4981 gacgaattct tccaaagcag ttttgttttg cgctgcttgg aggttttcga catctaattg
     5041 ccggatcagc agttgtgctt tttttgtcag gtagctttct tgctgttcca cgatctgctg
     5101 ttgaaaataa tgggaaatca attgccagcc accaaaaaac aaactaacta aaagaataag
     5161 aaagaagaga cgttcataaa tttttttcca tttcatcgtt tgggttcctg aaacttatag
     5221 ccaaatcctc taatagtcac caagtacttt gggtgttttg gatctcgctc gattttttct
     5281 cgcaaatgac taacgtgtac atctacgatt cggctttgtc ctgcgaagtc aaaattccaa
     5341 atgcggtcta gcaatgtgtc tcggtcgatc acacggtctt ttcgtttcat gaaataaaca
     5401 agtaattcaa attctttcgg tgttagttca atcagatggt cgtctacggt cacttgataa
     5461 ttggtcaaat cagcagtgat ttgtccaatc gatagatatt caggctcagc ttcatctttt
     5521 gattgcttac gaggttcaat tcgtctgaat attgctttca tacgggctaa tacttcgcga
     5581 ggactaaatg gtttggtcaa atagtcgtca gcacctattt ctaggccaat gatccgatcc
     5641 acttggtcat ctttagccgt cagcatcaaa atcggtgttt catttttttc ttgacgcagc
     5701 cgctgagtga tctccatgcc atccatcgtt ggaagcatca catctaaaat gatgaaatca
     5761 aatgattgtt ctaatgctaa ttctaatcct tcgcctccat ctgtggcact ggttaccttg
     5821 tagccttctt tttccaaatt gaacgtcaag agcgttacaa tagaaggttc atcatcaaca
     5881 actagtattt ttttcattca aatctccttt aaataggttt cattctgttt atattttagc
     5941 atagaatcag tacaaagggc tattttacaa aagaaataaa tggtataata ggaaggcact
     6001 ttgctgaata gaaaggaaga gcagtcaatg attggaatca gtgcatgttt aggcggtctg
     6061 gcctgtcgct atgatggaca gaaaaaagaa gtaccagaat tgatggaact agttgaaact
     6121 ggagaagctg tcatggtctg tccagaagtg atcggcggat taccaattcc tagagatccc
     6181 gctgaaatca ttggtggaaa tggattcgat gtgtggaaag atcaagcaaa agtatggacg
     6241 acaagcggcg aagatgtaac ggaagcgtac aaaaatggcg cgatcaaagc ctatcaaaaa
     6301 ttgcaggaaa aacacattga tctagtcatc atgaaggaaa aaagcccttc atgcggaacc
     6361 cattcgattt atgacggaag tttttccgga ataaaaaaaa atggtgccgg agtggctact
     6421 gcttatttta ttcagcaaaa aatgactgtg ctctctgatg aagaatggct gaaaactaga
     6481 ggtgagcaga atggaaatcg aaaagaccaa tcgaatgaac gcgctctttg aattttattc
     6541 gaccttattg acagaaaaac aaatgaacta catggaatta tattatgcag atgatttttc
     6601 attaggtgag atcgcggaag aatacgaagt aagccgacaa gcagtatatg acaatatcaa
     6661 gcggacaagc aagatcttgg aggattatga aaaaaaactc catctttttt ctaattatat
     6721 tgttcgagaa caggtattgg aaaatatgac tgcatatatt acagataagt acccggaaga
     6781 taaaaaacta cttgaatatg tacagcaaat tcaagcaatc gaagaataaa taaaaggaat
     6841 gaagaaaata tggcatttga aagcttaact gaacgtctcc agcaggcgat gggaaaaata
     6901 agaaaaaaag gaaaagtatc agaagctgac gtaaaagaaa tgatgcggga aatccgcctt
     6961 gccttactag aagccgatgt taacttgcaa gtagtcaaag attttactaa gcgcgtacgc
     7021 gaacgtgcgg taggggcaga agtgctggaa agtttatcac ctgcacaaca aatcgtaaaa
     7081 atcgttgatg aagaattgac gatcacactt ggttctgaaa cagcagagtt aaataaatca
     7141 ccaaaaatac caactgttat catgatggct ggtcttcaag gggcaggtaa aacgaccttt
     7201 actggtaaat tagccaatta tttaaagaaa aatgaaaatg ctcgtccgct cctaatcgca
     7261 ggggacgtat atcgaccagc tgcgatcgac caattgaaag tattaggtca acagctagac
     7321 gttcctgtat ttgatatggg aactgaagtc agcccggtag agatcgtccg tcaagggatg
     7381 gagttagcaa aagaaaagaa aaacgactat gtattgatcg atacggcagg acgtctgcat
     7441 atcgatgaaa cattgatgga tgagttgaaa caaatcaaag aattgacgca accaaatgag
     7501 attttgcttg ttgtcgatgc catgactggt caagatgccg tcaacgtagc tgatagcttc
     7561 aaccagcaat taggtattac aggggtcgtc atcactaaac ttgatgggga tactcgaggc
     7621 ggggcagcac tatcgatccg ctcagtgaca ggcgcaccaa tcaaattcat cggttctggt
     7681 gaaaaattga ctgacttaga agtattccac ccagatcgta tggctagccg tatccttggt
     7741 atgggggata tgctgacatt gattgaaaaa gcgcagcaag actacgacga gaaaaaagcg
     7801 gaagaacttg cacagaaaat gcgggaaaat tcattcgatt tcaatgactt tattgaacag
     7861 cttgatcaag tgatgggtat gggcccactg gaagatctaa tcaaaatgat cccaggaatg
     7921 aatcaagtcc ctggaatcga aaacgtcaag gtagatccaa aagatgttga acgcaaaaaa
     7981 gcgatggttt attctatgac gccagcagaa agagcaaatc ctgatctgtt gaacccaagc
     8041 cgtcgtcgcc gaattgctgc cggttctgga aacagtgttg ttgaagtgaa tcgaatgatc
     8101 aaacaattca aggaatcaag aaaaatgatg cagcaaatgt ccaaagggga tatgaacatc
     8161 ccaggtatgg accaaatgtt tggttcaggc gtcaaaggaa aactaggcaa aatggcgatg
     8221 aatcgaatga tcaagaaaaa taagaagaaa aagaaaaaac ggaaataaga tgaaaaaaac
     8281 agcttcggta cagactgaaa atgtctactg ccggagcttt tctatcagca atttttattc
     8341 tttactaata caattactct aaacgaagag gtggcacaga tgagatgtcc gtggagtgaa
     8401 caaacagaaa gtatgcggca atatcatgat actgtctggg gtgttcctga atatgatgac
     8461 caaaagctgt tccgaaaatt gatgcttgat attaatcaag ccggattgag ctggcagacg
     8521 attttaaata aaagtgaagc attcgatgaa gcatatgatc gattcgatat caaaaaagtc
     8581 gcaaattatg gagaaacaaa aatcagtgaa ctaatggaaa acaaaggaat tattcgtaac
     8641 cgaagaaaaa tcgaagcagc cgtccaaaac gccaaagcag tcttgaaaat tcaagaagaa
     8701 atcggcagtt tttcagagta tctttggtcg ttttctaatg gaaaaatcgt tgattcttct
     8761 tatcattcac aagaagaagt cccaacaaca agtcctcttt cagatgaatt agcaaaagat
     8821 ctaaagaaaa gaggatttaa atttatcgga agcacaacaa tctatgcttt tttagaagct
     8881 gtcgggatca tcaatgatca ccttgacagt tgtttccgca aagaagaggt cgtacgtatc
     8941 ggcagaaagg gcgaataaag catgcgaaaa atcatatttt atggtgctat aagtttagat
     9001 ggctatttgg caacgaaaac ggatgatctt caatggcttt ttgacactcc aacaggtaag
     9061 caaactactt atgaagcttt ttatgaaaca atcgatacga ccatcatggg cagaaaaact
     9121 tatcaggaag caaaaaaata tttggagacc gaagcaattt atccagagaa aaagaatttc
     9181 gttttttcca cccacgcaca attacaattg ccagatgctg aggtcgtaaa cgaagatcct
     9241 gttgcttttc taaaaaatct acaaatgaca gaaggaaaag atatctgggt tgtgggtggc
     9301 ggtcgattga tcaaaccgct attggaacat caaatgattg atgaatggta tatccagatt
     9361 acccctgtat tattagggga cgggattcct ttattccaaa aaggaacata tgaagcgcgt
     9421 tttgaaatgc tagacacgac acgattcggt gaatttatcg aattgcatta tgtacgaaag
     9481 tagaagtaaa taaaataaaa aaggcaacta tatgcagaaa tgtcctgtac atagttgcct
     9541 tttttattac cgttatgctt tttactctgt taatttgtta gaaaaatcta gatacgcatc
     9601 taaaatcgtt tggaagaaac ttaatgttcc ttcaacgata ttaccatttt catcaattag
     9661 attcgcaacg tttccgatat atgcttccgg ttgctgcaag gttggcacat tcaaaaagac
     9721 aagtgattgg cgtagatggt ggtttgcgcc aaagccgccg atcccacctg gtgatgcagt
     9781 aacgactaaa cctggtttat gatcccaaac actgtgtcca taaggtcttg agcctacatc
     9841 taaagcattt ttcaatactg ctggcacaga acggttgtat tcaggagtaa cgaaaacgac
     9901 accgtctagt cccctcactt cctcacgaaa acgagtccat tcagcaggag cctgttctgg
     9961 agtttcgaga tcctcattgt aaaatggcag atcatcgatt tttacaaata cactttcgta
    10021 cccttcagga agcaatttcg caaaagcttc tgctactttt ttgttgtaag aatcttttct
    10081 taaactacca ataaaaaatc caattttttt tgtcatacga tttttcctcc ttcaaactat
    10141 ctataataat cttacaaaag ataagtaact ggagcaaata aaaacactta ctgacaaaag
    10201 ctacatagaa gatagattac ttatttttaa caaaaaagaa gtctaaaatc ttctattttc
    10261 taaaaaaaat cgaatttaat caagctgtaa agaaaaaaag ctttacaggg taaaaaaaaa
    10321 ctgttacact acatcttgtg aataaaacaa tggaggtgga aataaataat ggcagttaaa
    10381 atccgtttaa aacgtatggg ttctaaaaag agtccgtttt accgtatcgt cgtagctgat
    10441 tcacgttctc ctcgtgatgg acgtttcatc gaaactgtag gtacttacaa tcctttgaaa
    10501 gaccctgcag aagtagtttt aaaagaagac ttagttcttg actggttatc aaaaggtgca
    10561 caaccttctg acactgtacg taacatcctt tcaaaagaag gcgttatgca aaaacaccac
    10621 gaagctaaat tctcaaagaa ataaggtgac cggatatgaa agatttaagc gacttagtct
    10681 taacaatcgt tcgtccgcta gtcacttatc ctgatcaagt caagttagac gtcgtagagt
    10741 cgaaagactt ttacgagtac aatctaacag tggctcctga agatattggc cgtatcattg
    10801 gaaaacaagg gcgtgttgct aaagcaatcc gcacaatcgt ttacggtgtt cggatcaatg
    10861 caccgaaaaa agtgcgtttg aatatcatcg atgataagga aaagtaaata aacgtgctgt
    10921 actcgaattt tcgagtgcag cttttttgtt ttttttatta attgaagaaa tgattatttg
    10981 gcaaaacaag caagaaagcg tatccttata ggaggaggga gtgaacagcc aatgagaaag
    11041 aaaatgttat ttattccatt tgctctattg ttaagcgctt gtagttcggt tactcaagaa
    11101 tcagacaata cacatctatc aagcagtata tctgaaactg ttaccagtcc agaaaaaagt
    11161 agtaccaaaa cggcttccac cactgaacaa acaatggcta cctcaaataa tgagaaaaag
    11221 actgctttag accagttgaa agaacaacag ccaaatgttc ccatgcctct agatgtacca
    11281 gtctcttcag gctatctcaa tatcgcagcg acacatacaa agcaaggtta ttctatttta
    11341 tattacagaa cagatcgtcc cctcgggttg aatgctgacg aattgaatca agaaacgcct
    11401 attgcaacct atctatatca atatgggttt gcttctagtc aagaaacaat ccaagttttg
    11461 cagccatttg agatcgacac aaatggtcag caagtggact taggttctcg aatcacaggg
    11521 tatcagcaag gtgcagcagg ttcaagtttt cttgaatggc aagaaggaaa ctggcgtatt
    11581 cgaatccgtg ggaataatat agaaggccaa gatcccttac tattagctaa agaaatcgta
    11641 gcttatttgg aagaaaacag tctaccagca cctgaacaat ttggtaaaat tactgttgat
    11701 atgggtgata cgacgaatcg agccgtagaa gtaagctggc aagaaccgaa aaatgcctat
    11761 acgatcactc atcaagatcc tatgtctgcg ttgaagatgg cagtttctat gaagaggttg
    11821 tgaaatcagc gcgctgatct gagcccatca tttaactcca agtcacagga agtaatcaaa
    11881 aatagcacgc cgcatttttg cataattttg gcttaatacc ttaaaagaaa actagaattg
    11941 cctcttcaca catgctaaaa taaaacagac aaaaaagaaa tggggatata agttgactga
    12001 atacttgaat gtaggaaaaa tcgtaaacac acaaggtatc aaaggcgaag tccgtgttat
    12061 ctcaacaacg gatttcccag aagaacgtta caaaaaagga acggtgctaa cactattcca
    12121 agacggaaaa gcacctgtgg aattaacagt caaaagtcat cgcaaacata aaaattttga
    12181 cttattgagt tttgaaggac atccttctat caatgatgtg gaaaaatatc gggatggcat
    12241 attaaaagtg tcaaaagaca actctgtaga tctagctgaa aatgaattct attaccatga
    12301 gatcatcggt ctgcatgtat tagaagatgg aactgagtta ggtaaagtaa aagaaatctt
    12361 gtcaccaggt gccaatgatg tttgggtcgt tcaacgtccg aaaaaagctg atatattgct
    12421 tccatatatc gcttctgtcg tcaaagaagt cgatttagaa gctggagtgg tccgtgtaga
    12481 aattccagaa ggactgattg acgatgaaga ttgatgtatt gactttattt ccaagaatgt
    12541 ttgaaggtcc tatgggggaa tccatcatcg gtaaggctgt agataaagga ttattagata
    12601 tcaatatctc taacttccgc gattattcag ataacaaaca tcagacagta gatgattatc
    12661 catacggcgg tggagcaggt atgctgctca aagtccagcc catctatgat aacatccaag
    12721 ccattgaaaa agctgcaccg gatgtcaaaa aaagagtaat tcttcttgac ccagctggta
    12781 aacgattcga tcagaaaatg gcagaagaat tttcacaaga agaacactta gtattcattt
    12841 gtggtcatta tgagggatat gatgaacgta tccgcacatt agtgacagat gaagtttcct
    12901 taggagatta tgtccttact gggggagaat taggtgcgat ggtcatgatc gatgcaacag
    12961 ttcggctttt gccagatgtg ttagggaatc agacttcagc tcaaacggat tcttattcaa
    13021 ccggtttatt ggaacatccc caatatactc gcccggcaga atataaaggg atgaaagtac
    13081 cagaagtatt gacaaatgga aatcataaat tgattgaaga atggcaatta aaagaatcac
    13141 taagaaggac ctatcaacgt cggcctgatc ttttggaaac acttgaatgg acacctcaaa
    13201 tgacgaaatt tttagaagaa atcaagaaag aagaacaaga aaaaacagca gatgaagcca
    13261 agtgactttt tctaaaatct tctttacagt aggttgataa tatgttagta ttttatggtg
    13321 agtgcaaaag cacttaacta ttacgatatt ccgctgtgag aaaagctcat aagaatattt
    13381 ggaataagga gaagaaaacc atgaatccat taatcgaaga attaacaaaa gaacaattac
    13441 gttctgacat cccagcgttc cgccctggtg acactgtgcg tgttcacgca aaagttgttg
    13501 aaggtactcg tgaacgtatc cagttatttg aaggtgttgt tatcaaacgc cgcggtgctg
    13561 gaatcagcga aacttataca gtacgtaaag tttctaacgg agtgggcgtt gaacgtacat
    13621 tcccattgca tacaccacgt gttgcaaaaa tcgaagtagt tcgctacggt aaagtacgtc
    13681 gtgcaaaatt gtactaccta cgtgcattac acggaaaagc tgctcgtatc aaagaaatca
    13741 gaagataaac acggaaaact tccttggaaa tctgaaattt gtgaaaagtc cttgtatatc
    13801 aagggctttt tcttttttct ctatcacagt tttaagccat ttttggctgt tttggaccat
    13861 ttttcaatca tattccctta aaaattgtcc tagattgtcc gacattgact atcagtgtcg
    13921 tcaaaatagg gcaaaattta gtagtcagct tgacgacaaa tataatacga aaaataccaa
    13981 aacatttacc gaatttagca acttttgaac ccaagtttct caaagggtca gctattagca
    14041 aaaaagacaa aacatgtact tttctactaa aaagttgatg tgataggctt ctatctaaat
    14101 aactattagg agtttttatc gtgaagcaaa atgatggacg tatcatttgg aaaaatcaaa
    14161 gtgagttaaa actgatttta acaattaatg aattcatcga aaaacacgga attacatcta
    14221 gccgtcaata ccagaaaaag ctatcagaaa atccaaattc tgcaccaagt atgtggttca
    14281 ttaacaaaaa atatggatca tgggagaatt tattgattag tataggacga gaaaatactg
    14341 ggtatggaaa atgggctaga atgtcagaac aagaattatt ggaaatagta gaagccttta
    14401 ttaagtgcga gaagataacc tctcaacgaa tgtacgaaca aaaatcagta gggaagaata
    14461 ttccttcact tagtaccatt aaaaagatgt taggagatat acgtccactt tttaaagaaa
    14521 aaaatgatgg atctcgattt actgatttcg aactgctgtt agaactaaaa aatgaaataa
    14581 tccgattaaa actacaggat gatttatcaa tgacaaagtt tcgaaaacta gttcaatccc
    14641 caaaactacc atcagttgat acaattatga aaagaacgaa caaaaattgg gaggaattga
    14701 tggcagagat tggatttgat tatcgaagaa tcaaaattta taagcagaga aacaacctat
    14761 ccaagacaaa gaaaactaaa tagtatcact ctaaatcaga cgttcaaaat taaaatttgg
    14821 acgtcttttt tattacccaa aaacgaaagg agatttattt tatgaaaaag ccaagattta
    14881 agaattggcg tttgctcgca acactgagtc tattatgcca aacaattggt ggatcgcttg
    14941 gcccaacgat tgcctttgct gatgaaatta ctcatccaca aacggtaact gtggaattgg
    15001 atttggctca ccagtatgct gtcgaaggta catttagcga tggtcgtccc atgtcagaag
    15061 ttaccgttcc gcactatgca gtttacaatg gtgtgaagca agatattttc tgtattgagc
    15121 caggggtgcc gatttacaat gagttcactc ctggttatga gaaaaatcca ttgcctgata
    15181 tgtcggagaa agcgaaatta gtttccgttt tatggaagga agctggtacg gatgtggata
    15241 cacatattgt ggcccagaag atgatttggc aagaagttaa tggctacacg cttcactcaa
    15301 ttaaacgttc tgatggtagt gcagtaaata tcgcagccat tgagtcaaaa atcaatcaag
    15361 ccattgcgga ttatcaaaag aaaccaagct tccataactc cacagtgaaa accgtgttag
    15421 gtcaatcgac tactgtgaca gatacgaacg gcttgaattt atcggagttt gatgaagttg
    15481 tcgagaatat cgcaaatatt gattatcgtg tgaacggcaa tcaactagtg attactccaa
    15541 atgccaattc aaaagagagt ggtgaattaa ccctaaagaa gtcagctaat acaggaacac
    15601 cggtagctta taaaatggct ggtcaacaaa ctttgatggc gggggcaatt gataagccca
    15661 atacctacac aatcaaaatt gatgtggaaa ctgagggttc tttgaagatt aaaaaagtcg
    15721 ataaagaaac aggaaatgtt gtaccgggaa ccgttttcca tttagacttt ggaaaaacat
    15781 tacctgcaaa agacgtgacc accgataaag aaggcattgc gacattggat gagattcctc
    15841 atggcgcgaa agtaaccatt actgaaaaat cagtgccagc tccttatacg attgacacta
    15901 caccaatcac cgcaaccatt aaatctggtg agactatttc tgtgacttca aaaaatactc
    15961 gcgaaaaagg tcaaatcatt ttgaataaaa tgggggtgga aacaggaact gatctttgga
    16021 acgacaaata ctcattagcc ggaaatacgt ttgccattcg caaagacagt ccaaccggtg
    16081 aaattgtcca agaaatgacc acggatgaaa aaggtcatgc ggaaacacca aaagagattg
    16141 ccaatgcgtt ggaattggga acctattatg tgaccgaaac caaagctagt aatggctttg
    16201 tgaatacctt taaaccagta aaagtcgaat tgaactatgt caatcaaacc gtggctcttg
    16261 ttaccagtaa cgtaaaaggg caaaaccaag aaatcactgg tgaaaccact ttgacaaaag
    16321 aagacaaaga taccggtaat gaaactcaag gtaaagctga gtttaaagga gctgaatata
    16381 ctctctttac tgcaaaagat ggtcaagcgg tcaaatggag tgaggctttt aaaccagagt
    16441 tagtgaaggg aacgaaagct tctgatgaaa cggtgacttt gactttagat gaaaagaatc
    16501 aagttgctgt taaacactta gcgattaatg agtattactg gcaagaaacc aaagcacctg
    16561 aaggatatac cttggatgaa acaaagtacc ctgtttccat caaaaaggtg gatgataacg
    16621 aaaaaaatgc cgtgattacc cgagatgtta cggcaaaaga acaagtcatt cgctttggct
    16681 ttgatttctt taaatttgct ggatcagctg ctgggactgc cgaaactggc ttcaatgatc
    16741 tgacctttaa agtatcgcca ttggaaggaa ccagtgagat tacaggtgcc gaagatgaag
    16801 caattacagc ttataacgag caactaggtt ttgatggcta tggcaagttt gaaaatcttc
    16861 cttatgggga ttatttactt gaagaagtag aggctccaga aggatttcaa aaaattacgc
    16921 cattagaaat ccgttctact tttaaagaaa ataaagcgga ttacactaag agtgaataca
    16981 tttttacgat taccgaaaaa ggacaaaaac aaccaattaa aacggtgacc gttccttacg
    17041 agaaactgac gaataaagca ttttctgtta gcttgaatcg tttgatgctc tatgatttac
    17101 ctgaagaaga agatagctta acttctcttg ggacttggaa agacggaggc aaagaattga
    17161 cagaccttga ttctaccgag ctagttgata aattgagcta taacttgcat gaaatcaaag
    17221 aagactggta tgtggtagcg caagccattg atgtggaagc gacaaaagct gcccaagaaa
    17281 aagatgaaaa agccaaacca gtggtaattg ccgaaacaac cgcaacgttg gcgaataaag
    17341 agaaaacagg aacttggaaa attttgcata aattaaccgc agaacaagtt ttggataaaa
    17401 ccatcgtctt attcaactat gtgtatgaaa acaagaaacc ctatgaagca ggtgatgatc
    17461 cagtagcgaa agatgctagc ttgaacaatc aagcccaaac tgtcaattgt acggtggaac
    17521 gccatgtttc catccaaaca aaagcccacc tagaagatgg ttcgcaaacc tttactcatg
    17581 gggatgtggt ggatatgttc gatgatgtgt cgattaccca tgatgtactg gatggctcaa
    17641 aagaagcttt tgaaacaatt ctgtatgcat tacttccgga taatacgacc aaagaaattt
    17701 ggaaatctgg caaaattgat tatgaagtga atgacaaaga attcactaaa accgtacttg
    17761 cggaaaaagt ggacacaagt aaatatccag aaggtacaag ttttaccttc aaagaaatta
    17821 actatggcaa agacggaaac atcaatggga aacacaatga ggatctaaaa gaaaaaactc
    17881 aaactttaac acctaaaaaa gttccgacaa caccaagtgc accagaacaa ccggaaatac
    17941 caactgttcc aagtgactct caagaatcta gtcctacagt aaagacattc ccacaaacag
    18001 gggagaaaaa ttctaatgtt ctgctgttta ttgggtttac cttgatcttt gcgactgctg
    18061 ggtattattt ctggaatcgc cgaaactaag gtgatgtgat gaaacaacta aataggaaaa
    18121 accaacgtgc gcgaccgcct cctaaaaaaa gtggtcgcgc tatttttgta tccaaaacta
    18181 aaaatgaaaa gaggaaaaga agatggaatt gaaatttgtt gtgccagata tggccgaaac
    18241 ctttggaaag ataaggtatg ccggcgaagg cgaagtttta actgaaggat atgggcggaa
    18301 tactacagta attggtcgta gttatcattt gtattccagt aagcaacgag ccgatgatat
    18361 tgaagtggtg gtagctgcgg aagccggcga aaaggatttt gatcaagatc aaccactaaa
    18421 agccgtgaat ccccatttgg ttgccaaagg ctatgagatt gagaatcgtg ggtttaccga
    18481 ctacgtgttg tatgtcgatg atttagtgaa agcataggag gaaaagaaga tgagattaac
    18541 agaaggtatt gttgtagatt caggactaac gtttgggaaa ttacgatttt ccgcattacg
    18601 ccgagaagta cggaagcaaa atgaggatgg aacggttagt aacgaggtaa aagaacggac
    18661 ttataatttg aaatcctctg cgcaaggtcg aatgatccaa gttagtatcc cagcaaatgt
    18721 acccttacgc gagtttgcct atgacgcaga ggtagagttg gtcaatccaa tcatggatac
    18781 ggtcgccaat tatgttttcc gagaaggaac tactgtcaat tggttcatta aggccgatga
    18841 tttagtcttg aaacgacaac cagatcaggg aaattctaca aaccaaaatg aaggaaagaa
    18901 ataggtgaag cgtatggaaa ttaatgttga acatatttta gattgtctcg atcaatatgg
    18961 aaaaggtgag ctaacggagg aacaactcac taaagcatta acctatgatg aaaaaatgtt
    19021 tctgattatg catcaagggt tactggaagt aggtaacgat gccgaagaag attttgatgt
    19081 actgaattgg ttaggggaag aagagtcctt ctttatggtt atcgaagtaa atgaaagtct
    19141 atgtcgagaa gccgaaaccg tattggaaga aattggtgtg gaaatgccgg atgccattga
    19201 agttttttta aagcaactag tggaaacgaa acaactccct atagcagtaa atgactagca
    19261 taactgcttg aaattggatc aatgaaatcc tatgaagctt ttttcgattg gaggtggaaa
    19321 ccataaaaat gtacaaaggg catcgtatac gggcaggaga tcagcacttg gtttatcact
    19381 ttgttcttgg ctggctactc gctctgttca tcggttggat gagcgtcttt tattttcaag
    19441 agcttagaca atttgatatt tctaagctat cactttctac tatagaaatc gttcgttcta
    19501 taaaagattt aatctatttg ctaggaagtc tcgttctttc aggaagcacg atgttgcttt
    19561 atatacactt ttttcaggat cattggcgca gtttgtggca tcgacaaaag ctagcccgga
    19621 tgattctaga aaatcattgg tacgaagtaa aacaaactca gagtgaagga tttttcaaag
    19681 acctcaatag tagtcgaacc aaagagacaa tcagttactt ccccaaaatc tattaccgta
    19741 tgaaggatgg tttactttct attcgcgttc aaatttcact gggaaaatat caagatcagc
    19801 ttttaaagct ggaaaagaag ttagaaagtg gtctatattg tgaactagta gaaaaggaac
    19861 tcaaagactc ctatgtggag tacactttac tgtatgatat aattgccaat cgaattggga
    19921 tagacgaagt agtggcagaa agtggggctt tgcgattgat gaaaaatcaa gtatgggctt
    19981 atgattcttt acctcatatg ttaatcgctg gcggcacagg tggtgggaag acttactttt
    20041 tactcactat catcgaggct ttattaaaat ctgatgccga gctttttgtt cttgatccca
    20101 aaaatgcgga cttagccgat ttaggtacgg taatgcctca tgtctattcc caaaaggagg
    20161 aaatttctgc ttgtgtggaa gatttctatg agcgcatgat gactcgtagc aaggcaatga
    20221 aagaaatgcc caactacaaa acaggagaga attatgcgtt tcttggactt ccaccaaact
    20281 ttttaatctt tgatgaatac gtggtttata tggaaatgtt aacgacgaag gaaagtgcgg
    20341 tgattttgaa taagctcaaa caaatcgtga tgttaggtcg tcaatctggt ttctttctga
    20401 ttctagcttg tcaaagaccg gatgcgaaat atttaggaga cgggattcgc gatcaatgtg
    20461 cgacatgttt ctaactgaaa aggttaggca cttaaaagaa gaaaacataa gtttcctttt
    20521 aaggagaact gatattttga gcagtggaat gatggggtaa cgccctgaaa cgctccctta
    20581 atactccgac tggctgttta acatatagct gttagatggt cagaagctcg gtgaagtcgg
    20641 ctgaaagtta ccgtaaatat gataaattca tatacgaaag ttgttcagag gtgaatgatg
    20701 taacctatag gtcggaggtc tataaaatac tcacggtgag aatgtaagta atactactga
    20761 cgaacttgcg aatgaaagaa tctatacacg gactgtatag aaatgtacag gattctaccg
    20821 tatcaacgga acagaatgta tgttgtggtt tagtaagatt attggttatg aacaaccatg
    20881 caatgttaca ggcattggaa atatacaggt tcaaagcaag cacctaaaag tatatataaa
    20941 gataaaaata tcgaaacatg ggaagctggc aatgtggagg aaactatatt ccattgaaac
    21001 atttgtgacg aagaataata agcacattta tgccagtgaa agtggtggca cagtaccaat
    21061 gaggatatag aaatatatcg gaggaatagc cactagtcaa aagaaatcgt taattaaatg
    21121 atgtatttca tagaatcgag taagacaaaa taaacactac aacctaagta aacaaaggta
    21181 gtggtgctat gaataaagta aaaacaaata aaacacttcg tcatagtgaa tactatggca
    21241 tgacacaaat atttgatgaa ctgtatgtaa aaagtgataa aaaagaagtt tttacagagc
    21301 tcatgacaat tattatgagt gatgaaaata ttcgactagc atacagaaat atcaagaata
    21361 acaagggcag ttatacagcg agtaccgata agaaaagtat tcgagacatt aaaacactgt
    21421 cagaagatac ctttctaact gaggttaaag ttctttttcg ctgttacaaa ccacgagcag
    21481 ttagacgtgt agaaattccc aaaccaaatg gaaaaacacg ccctctgggc attccatcaa
    21541 tctgggatag gttaatacaa cagtgtattt tacaagtctt agaaccgata tgcgaagcta
    21601 aatttcacaa ttatagttat ggatttcgac caaaccgttc cacacatcat gcgattgcta
    21661 cctgcaatcg actggcaaat agggggaagc tacactttgt agtagatgtt gatattaaag
    21721 gattctttga taatgtcaat cactctaaac ttttgcgtca aatgtggacg attggaatcc
    21781 gtgataaatg gctattaggt attattcgat ccatgctaaa tgctcctata gtcctaccaa
    21841 ccggtaaagt cgaacaccct aaaaaaggtg tacctcaagg tggtgtccta tcccctttac
    21901 tatctaatat catattgaat gaattagatt ggtgggttgc ttcacaatgg caaaatacca
    21961 cgattgagac agaaaagatt atggataggc gagataaagg caaaggcatt gataagacta
    22021 atcagtatcg ggcattaaga cgaacaaact taaaagaaat atacattgtt cggtatgctg
    22081 acgacttcaa aatcttttgt agaaaacgaa gtcatgcaga taaaatattt cacgcaacga
    22141 aaatgtggct taaagaacgg ttatcacttg aaattagcga agaaaaatcc aaaattgtca
    22201 atctcaaaaa aggtaaatca gaatatctag gatttgaatt aaagctaatc aagaaaggta
    22261 aaaaatacgt agtcgaaagt catatgagca aaaaatcaat gacaagagtt aaaatccaat
    22321 taaagaaaca attacgtaaa gttgccagac cgaagaatca ttgcgaacaa gcaaaagaaa
    22381 ttggattata taattctatg gtgattggaa tccatcaata ttatggaatt gcaacctgtg
    22441 taaatctcga ttgcagtaaa atagcctata cactaaaacc gttcatcaat cacaaactgc
    22501 cgacaaagaa acatggaaag atattaaata catttatcaa atcgaagtat ggaaaaagta
    22561 aagaaatgcg atggttgaat aatgtgccaa ttgtaccgct caactatgtt cagtttagac
    22621 ttgctgtccc cctatcagag ggaacttgca agtacactga aagtggacga agcaagatac
    22681 acagtaaatt aaaattagac ctagcccttt tacttcacat gatgagaaat agtaattatg
    22741 aaagaagtat tgaatttgtg gataacagaa tatctaaata ttctgctcaa aagggaaaat
    22801 gtgctatcac gggtaaattt ctcgaatacg aagaaatcca ttgccaccat atcgtaccag
    22861 taaaacaaca gggtacagac aaatacagca acctcattat tattcacaaa aatgttcacg
    22921 cattagtcca tgctatcgaa gaaaaaatca tacacaaata cctgaatgta ttaaatctaa
    22981 ccaatgaaca aatagaaaaa ctaaatgaat tacgtgtcaa agctggtaat agtgttttaa
    23041 cagtttaact tgaaaaatat atcatactta acattctttt gatggaacgc cgtatgaagt
    23101 gaaagtttca tgtacggtgt gaagcggggg aaaatctgga gatgacatca aaggattacc
    23161 tatcgctatt taatttccgg gtggctttgg gtcgtatgag tgaactggga tattccatga
    23221 tgtttggcga ggttgataaa aaattcttta tgaagcgtat caaaggtcga ggctatgtag
    23281 atacgggagg gagtgtgatt agtgagtttt atacgccact tgtaccaaaa ggatatgatt
    23341 tcttaaggga aattagcgac attggtggat taaacgttaa tacggaagga taaaataata
    23401 gtatgtagcc taggagtgtc aagaatcctg ggcttttttt acgaggtgat ttatgacatt
    23461 tttagattta ttcgctggga ttggtggctt ttgcttaggt atggaacaag cgggtcacca
    23521 gtgtatcggc ttttgtgaaa ttgatgattt tgctcgccag agttataagg caatccatga
    23581 tacaagtaag gaggtggaaa tgcatgacat cacaagtgta tcagacgagt ttattcaatc
    23641 tctcggacca gtggatatcc tttgcggtgg atttccgtgc caagcttttt caattgcggg
    23701 aaagcggcaa ggattttccg atactcgagg tactttattc tttgaaatcg ctcggttcgc
    23761 cgctattctc caacctaagt ttttattcct tgagaacgtc cggggattac tcaatcacga
    23821 aggaggggct acgttcgaga cgatcctccg aacgctggat ggattggggt atgatgtgga
    23881 atggcaagtg cttaactcaa aggcctacgt tccccaaaac cgtgagcgga tcttccttat
    23941 cggacattct cgagacgcat gtaccgaaca agtatttcct atcattggat cgtctccaac
    24001 atctgatcaa aacatcagaa acttattaaa tatcaaccct tccaatcgag gaatgggggg
    24061 acaagtctat gggtcagatg acgtagcgcc taccttgacc ggtgatgaag gaatcaaaat
    24121 cgcattgccg gtagatgatg gaatttctgt agcgggtatg ttactgggaa attttgaaca
    24181 aggcaatcgg gtttatgaga taactggaac agcgcctact ttgtcaacga aacaaggcgg
    24241 aacgaagatc atgcttcgga aaaacgaaac agaatatcaa gaggtgaagc cagggaacag
    24301 tgtgaacctg gcttttccta attccacaag tcgtcgaggc cgtctgggaa aacaaagtgt
    24361 gcatacctta ttaacaggag accaacaagc agtcgtcacg gatcagtatc aaattcgaaa
    24421 gttaacacct agggagtgct ggcggcttca gggctttccg gactgggctt ttgatcgagc
    24481 ttctcaagtc aattcagata gtcagttgta taagcaggct ggaaattctg taacagttcc
    24541 ggtcattttt gatattgcta gaagattaaa ggaggtaaaa acagatgatt tatgatgagt
    24601 tgattgggga atctactggg tgattggcaa gattcagtca gatccggaat tggaagaaga
    24661 actgtaccgg ctcaattttg atattcgcaa aaacggggtg aaagtccctg atgatccgta
    24721 tgtaattgat gaggaaacgg atgctcgaat ggagctgaat caagtcatca gtgaattgga
    24781 acgaattgcg gactttgcta aagaacctga tatccgccaa tacttgtttg agataaaagc
    24841 agagttggaa attgagggta ttaccgcgga gtaacggcca aataaaccac tgataggcac
    24901 tgaccgcggg ggatttgcga agcagaaatc ctccgtggtg ctgtgcctgt ttatggacgg
    24961 cgttagccgg ccatgatgtc tcaccccccg tatctaacag gggggtacaa aaacacaaaa
    25021 aataagcaag caacgataag gaatggctgt cctatcaagg ataataagca atttgtgtag
    25081 atgttaactg atttgaaaaa gttaacacct taaatttgga ggtgagaact tggcacaaag
    25141 gaatttagat tatcggctat taaaagaccg gcgtaatgaa tatggcgttt cacaaaataa
    25201 attagctacg acttgtggac ttagtcgccc gtacttaaat cagatagaaa atggtggcgt
    25261 aaccgcatcg acaaaaacca tgaggaaaat ttttgaccaa ctggaaagtt tcaatcccga
    25321 gttaccttta acgttactgt ttgactatgt aaggattcgc tttcccacaa cggatgcgag
    25381 gaaaatcatt caagagattc tccatttgaa atttgattat atgctccacg aagattacgc
    25441 cttttactcc tatcaagaac aatatgttat gggagatatt gtggtgatgt tgtcacatga
    25501 agaagataaa ggcgtccttt tagaattaaa gggtcgtggt tgtcggcagt ttgaaacttt
    25561 tttactcgcc caaaagcgta gctggtatga ctttttcgaa gattgtctaa aagccggtgg
    25621 cgtgatgaaa cgcttagacc tggcaatcaa tgatcgagtt ggcctgttag atattcctga
    25681 tttaacgaaa aaatgtcaga aggaagaatg tatctccttg tttcgtacct tcaaaagcta
    25741 tcgttccggg gaactgttga aacctgatga taaagatggt atgggcaata ctttgtatat
    25801 tggcagtctt aagagtgagg tctatttctg tttgtacgaa aaagactatg agcaatatat
    25861 caagttaggg attcctttag accagaccga aacgaaaaat cgttttgaaa tccgactgaa
    25921 aaatgatcga gcttatcatg caattcaaga tttgttaaaa ggtcgcagta ttgaaagtac
    25981 cacgttttcc attatcaatc ggtatttgcg atttgcggat aaagtagatg gaaaacggcg
    26041 aaccaattgg cccttgaatg aacaatgggg tcgttttatt ggacggaatc ggaaagagat
    26101 tcaattaact tctgaaccga aaccgtatac cattgaacga acattaaatt ggctaggtag
    26161 acaagtcgcc cctacgtgga aaatggctaa ggagttggat cgattgaatc aaacaacgta
    26221 tatccaggat atggtacaga atgcgcgact ctcggaccgg cataaaaaga ttttggagca
    26281 acaaagtatg gcaatcgaaa acttgattgt atgaaaagag gaattttgat ggaaattgta
    26341 aaagatatgt tattggtact tggtggcagt atgcttggtg ttaccgtgat gtgcttgatg
    26401 aatgcaagtg cagcagcgga ttgagcaatg gaaaagaaag gaaagtgaca aaatgaattt
    26461 cggacaaaat ttatgtgcga ctcgttcctt agtgaaaagc taaggcacta ataaaagaac
    26521 gaaaaagttt ggttattagg agaactgata atctgacagg tggaatgatg aagtaacgct
    26581 ctgaaacgcc tgccctgagc ctccgacaag cattgtatga ggaaactcag aatgtttgaa
    26641 gctcggtaaa gacggctgaa agataccgta atagttgatg aacatatatc ttctatcgaa
    26701 aactatccag aggtgggtag cgtatccaac aggtcggggg tctataaaat atctatggtt
    26761 agaatgttct ataaggaact gacgaaacag cgaatgtacg ggtctaaatt tgaactttgt
    26821 agaaatgcaa aggtacgaga aatcgtagct ggtgtggcaa agtaagaata taggttatga
    26881 aatgccatat aacgttacag gcggtatcaa gccagcaggc ttatagctag tgacctaagg
    26941 atatatatgt atagataaga ttatcggaac gaggaaaggt attgggttct catcaagaga
    27001 ataaactgac gaagaacaat aagcagttga actaatgctg aaaagcagag ggcgaaccta
    27061 agaaattctt gtaatgagaa tggaggaatg ccctcaagtc gtgtatatat tagaaaagta
    27121 ttatgttgtt tcaataagga ttacgagtaa gataaaaaag ctcactcaat ttcaagtaaa
    27181 ggagtgaagc cttatgccta aaaataaaaa tgaaacattg tgtgtagaag atttaagaca
    27241 cgctgaatat tacgaaatgc aaaacacctt tgatgattta tatgccaaaa gtaagaatgg
    27301 agatattttc actcatctta tggatattat cctatcgaga gaaaatatat tactggcata
    27361 tcgaaatatc aaagcaaatg caggcagtaa aacagcagga acagacggta caataattaa
    27421 agatattggc aaattgccag cagaaacagt tgtcaaaaaa gtaagataca ttgttgcagg
    27481 cagtccacat gggtatcgac ctaagccagt gaggcgaaaa gaaataccaa aaccaaatgg
    27541 taaaaccaga cctctaggta ttccttgtat gtgggacagg cttatacaac aatgtataaa
    27601 acaagtatta gaaccaatct gcgaagctaa atttagtgaa aacagctatg gttttagacc
    27661 taataggtca gttgaaaatg caataaaagc aacctataac cgcctacaaa tcagccagct
    27721 acattatgtg attgaatttg atattaaggg tttctttgac aacgtgaacc attccaagct
    27781 gataaaacag atatgggcta tgggaatacg ggacaagcac ttgatattca ttttaaaaag
    27841 gatattaaaa gctccaatca aaatgactaa cggtacaata acatatccag agaaaggaac
    27901 tccgcaaggg ggaataatat ccccactact agcaaacatt gttcttaatg agttagacca
    27961 ttgggtagaa agccaatggc aggaaaatcc tgttacaaaa aactatgtgg ttcatatcaa
    28021 taaaagcggt agcccatgta aaagcaacgc ttacaaagaa atgaagaaaa caaagttaaa
    28081 ggaaatgtat atggttcgtt atgcagatga ttttagagtt ttctgccgct acaaggaaag
    28141 tgctgaaaaa gccaaaatag caatcactca atggattgaa caacgattaa aattggaagt
    28201 atcacaagaa aaaacaagaa ttgtaaatgt tagaaaaaga tactccgact ttcttggttt
    28261 caagattaaa atgataccga gaagaaagaa gttagttgtt aaatcacata taagtgataa
    28321 acaattcaaa aaccaaaaag acaagctggt atcacaggca aagaaaattg cttctccctc
    28381 aaaagggaaa acggaattag aagaaacaag actttataat tcaatggtat taggtatgca
    28441 aaattattat cagattgcaa cgaatgtaaa tctggattgt atgaaactga atagagctgt
    28501 aatggctatc ttcactaaca gattaggtac aaacaaaagg ggcagattga gaaaaacagg
    28561 cagacaactt acgacaaagg aggcaacaag atatggtaaa tctaaaatgc ttcggtatgt
    28621 tgctggcgag ggcgaaccta ttttccctgt tggatatatc caacacagaa aaccaatggc
    28681 aaaggtgtat ttagcgaatt gctacactct agagggaaga aaatttatcc acaccaatct
    28741 aagtgttgat aaattactga tgtaccagtt aatgaaatta tctttggaaa atcgcacaat
    28801 agaatacgca gacaatcgaa tttcgctatt ttctgctcaa catggaaaat gtgctataac
    28861 tctggaagaa tttcaacaag ctaatgaaat acattgtcat catattgtac caactggagc
    28921 tggtggaaat gacgattata aaaatcttat tttggtaaaa gaggcggtac accgtctaat
    28981 acacgctaaa acagaagaaa caatacaaaa atatatagct ctattgaagc taaataaagt
    29041 ccagctcata agactaaata aatatagagt attagctggc aatcaagaat taaacttgat
    29101 ataggtctac tacataaata cttttcaata taaacacgat ggaacgcgga gtgcggtgaa
    29161 agtcgcacgc tccgtgtgaa tggggggaaa agtttgagat atttataata tcaggaactt
    29221 acctatccat atatcaatgg tttttaacca atgctcaatc tttagtctta ctagcgattg
    29281 tggtcattgg tttgttttta ggatttaaac gcgagttttc caaactgatt ggcttcttgg
    29341 tgattgcttt gattgcggta ggtctggtct ttaatgcttc tggtgtgaag gatgtcttac
    29401 tcaatttgtt taaccgaatt gtcggtgcct gagggggaat cacaatggaa cagatacgtg
    29461 tttatattgc gaaccttgga aaatacaatg aaggtgagtt ggtgggggca tggtttaccc
    29521 cacccgtcga ttttgatgaa gtgaaagaac ggattggatt aaatgacgaa tatgaagagt
    29581 acgcaattca tgattatgaa ctgccttttg agattgatga gtatacacca attgaggaaa
    29641 ttaatcggtt gtgtggttta gcggaagagc ttaaaggaac gccaattggt gaggtcgctt
    29701 cagagattca acatgccttc ttcaattctt tcgaggaaat ggtagagcat gtggatgata
    29761 tcatctatta tcccgattgt aatgacatga gtgatgtagc gtattacttg attgtagaag
    29821 ctggtgattt aggcgaagta ccagaacact tgaagacgta tattgatttt gatgcgtgtg
    29881 gtcgagactt ggagattggc gggaattatt tggttacgag tcgaggggtt tttgaactaa
    29941 tgtaaatcat ttgttagaat tgaccagaaa tttctatcgt acttttactt ttctatttga
    30001 tatactgaaa tagaaaatat ttgttgatag gggtgttact aatggttggc aataagtggt
    30061 acaaatgtga tcttcatatt cattcaactg cgagtcagtg ctttcaggat aaaaaggtta
    30121 ctgctaagga atgggtagaa gaatgtttaa acaaaggact cgattgtgtt gcattaactg
    30181 atcacaatac aggggaaaat attgatgaat ataagaaagt ggctatcgaa aatggcttag
    30241 atttttttcc tggagtggaa ttaacgtgtg gagaaaatgg aactcattta ctagtcctat
    30301 ttgataaaag tgcatgtaca aatgatatct ctgatttctt aaccaagatg ggtataaaaa
    30361 gagaggattg ggccagcgct gcagcttgct caatgaaatc agttttagaa gttattgatt
    30421 ttgctgagca cgagggcttg ctcgttattc ctgcacatat agatgagttt aatggaattt
    30481 cttcagcaaa atttggaaat ctaggaaaga tatttgaatc agaaaatata tatgcagtac
    30541 agacggttca aaaagaattt tttgaaaatc gctcacaaat gattccctca tctaagcgtg
    30601 acactatcta tgatagtgtg aatgccagat atgatggtag agttggaaaa gatactttgg
    30661 aatcttggta taaatcagtt gttgaggcag aaaaaaataa tatgacattt cttagctttt
    30721 ctgataaccc acactcgaaa ggaaattcaa aacatggact ttggggaata ggcacaagat
    30781 attcctatat aaaaatgaag gacgaacctg acttgggatc acttcgcgat gctttaatgc
    30841 taggcgaaac tcgagttcat tctgattttt ctaatttctc cattaatgaa aatgaagttt
    30901 tattggaaaa attaagcttt tctgggacca ctcttagcac aaaagaagtt gtagtcgaat
    30961 tcagcgataa tttaacttca attattggag gaagaggaac aggcaaatct tgtattacaa
    31021 gattcttggt ctatgtcctt ggaaaggaag cagaacttga tcaattttct gaaatacaaa
    31081 gtgattatca gaactttgca caaattgaac ataatggctc tggaatattt ttgaaggata
    31141 caattgtgaa actgaatatt ttctataagg ggacaaaata tcaaataata agaacacagg
    31201 atagacattc tatttatgaa tttacacaag agaatggtct ggttgaaaaa gaaacagaac
    31261 ggttgagaat gatttccgat aaggtgagta tatactctca aaaacaaatt tatgaaattt
    31321 caaaaaatca aactagtata ctagaattac tagatggata taactctgat ttgatttcag
    31381 agtataaaaa tgagattgaa acatgtgtaa acgaaataag aaaattaaat tgggatattg
    31441 tttctgtgaa aaaagaaata caagataagg cgaaggtaga gcttgaaatt gaagatttaa
    31501 aaaaacaagt agaaaagcta tctcataaga gttataaaga tgtttatgat gagtattcaa
    31561 aagagacaga tatttatagg gaactgaaac gtgatgtgga ggcacttaag gaaattccca
    31621 aaaatctaac tgatagtgtt gacaaaattg actttggcaa tggtataaaa gttacagacg
    31681 aaattgatga acaccgcgga gaattgatta agaatttagt gaccaatcgg gctaagattc
    31741 aaacaataat taatgaaatg tcagatgaaa ttgatagtta tagagcagag ctgaataaat
    31801 cagattggaa agttaactat aatgaggttt caaagaggta tcaaagaggt atcaaaaact
    31861 tagtgaagag ttatctcaag atgaattaaa aatgttacaa aaccttgatt ctttatatca
    31921 atctttatca aaaactgaag agcgattgga agaaattatt caacaagaaa taaagcttaa
    31981 agattaccaa gttgaggttg actcagcaat gtcaagaatg aataaatcat atcaaaatct
    32041 ctattctgag agaagtagtt cctcgcgcga aattttttct gatattacag gaatagaggc
    32101 tactattcaa ccaaataggg atttcaataa ttatgttaaa gagctcagag cttgtattaa
    32161 taaggaggac acttttgaca gtgagtttgg atctcttatt gataagctga caaaaaattc
    32221 cattactaat caagatatat ataatgacat acttgatata agagttagtg gggaaagtag
    32281 tattttttca gataaaaaat taatcaattc tataagaaaa ttgaatgatg cacaagttct
    32341 tgaattacaa acccttaagc caaatgattt agtagttatc cgacttgaac taaatggaaa
    32401 aaaagttagt ttatcgaatg ctagtgctgg tcaaaagaca tctgcaattc tttctatgat
    32461 tttggcgtat ggaaattcac cactcatatt ggatcagcct gaagatgatt tggatagtca
    32521 attaattaat aacttaatcg taagaagtat cattacaaaa aaggaaaaca gacaaatttt
    32581 aattgtaact cataatgcaa atatcccagt taatggtgat tcagaatggt tgattagcat
    32641 gggagattca aaagaaatat cggctgatca gtgcgggtcg gtagatgaac ccaatatcaa
    32701 gccaagaata tgtactgtga tggaaggtgg cgaggatgct tttacaaata gagcgaaacg
    32761 ctatggtttt aaacaaattg tagaataaca ctagagggtg agacatatta ttatgtccgc
    32821 cctttttagg aggaaaaatg aaaaaaataa aaagctatac cagtatctgg gcagttgaaa
    32881 aagtcattta cgcaatcaat gattttcagt tgccttttcc tgtgactttt aaccaaatgg
    32941 cttggttcgt tttatcttta ctgtttgtca tcgtatttgc ccatgtgcct ccactatcta
    33001 tgatagagga ggtcttttta aaatacttag gcataccggt ggctgtcact tggtttatgt
    33061 cgcaaaagac gtttgatggc aagaaaccac tgggattttt acgatccttt atcagctatc
    33121 acttgcgatt taaggtgact tttgcaggaa agaaagtcaa agaacagaag aaacgatggg
    33181 atgaacccag tactcttgta aggagtgtga actatgtatc cgattaagta tattgaaaat
    33241 aatctcgtct ttaaccaaga aggcgagtgt tttgcctact atgaattagt gccttacaat
    33301 tactcctttt tgtcacccga acagaaattt caagtgcatg ataactttcg ccaactaatt
    33361 gcgcaaaatc gtgaaggcaa gatccatgcg ttacaaattg ccacagaaag tagtattcgc
    33421 gccacacaag aacgatcaaa aaaagaaatt accggtagac tcaaagaagt agcgaaacaa
    33481 cgaattgata tacagacaga tgcattagta tccatgattg gcgatagtca gattgattat
    33541 cgctttttta ttggctttaa actaattgcg acagatgaag aagtcaatct aaagagtctc
    33601 aagaaatctt tcttttctgg gcttcaagaa tttgtctatg gagtgaatca tcatttgatg
    33661 ggcgattttg tttccttatc caatgaagaa attcgctgct attctaagct tgaaaaatta
    33721 atggaaagca aattggctcg aagatttaaa gtcaggcgag tcacaccgag tgacctgacg
    33781 tatttgattg aacatattta tggcgaaaaa gggataccgt ttgaagaata cgaatttcag
    33841 ctaccaaaga aaaagctaaa atcagaaaca ctggtgaaac gttatgactt attacgtcca
    33901 aatcgttgtt taattgaaga aaaaccaagg tgcttacgga tggaacatga gaatcatgag
    33961 tcgtacgtag cgtatttaac aattaataca attgtggggg agatggaatt tccttcctca
    34021 gaacttttct attaccagca acaacaattt acattcccaa tcgacacaag tatgaatgta
    34081 gagattgtga cgaataaaaa ggctttagct accgttcgta ataagaaaaa agaactgaaa
    34141 gatttagaca atcatgctta ccaatctgac aatgaaacga attccaatgt cttagatgct
    34201 ttggattccg tggatgaatt ggaaaccacc ttggatcagt caaaagaatc tatgtacaaa
    34261 ctgagttatg tggttcgagt gagtgccgaa tcagtggatg aactaaagcg acgctgtgat
    34321 gaagtgctcg atttttatga tgataccaat gtaaaactag tccggccctt tggcgatatg
    34381 atggggctac atgaagaatt cttaccctca agtaaacgat atatgaacga ctatattcag
    34441 tatgttacgt ctgatttttt ggcggggctt ggttttgggg ctactcagat gctaggagaa
    34501 ttagaaggga tttactttgg ctacaatgtg gatacaggtc gtaatgttta cctgaaaccg
    34561 gcattggctt cacaaggagt caagggttca gtaaccaatg cgctggccgc cgctttcctg
    34621 ggttctcttg gtggaggtaa atcctttagt aacaatctct tagtctacta tgctgttttg
    34681 ttcggtggtc aagctgtgat tgtcgatcca aaaggggagc gaggagggtg gaaagaaacc
    34741 ttgccagaaa ttgcggatga aatcagtatc ctcaacttga cgagtaagtc agaaaatcaa
    34801 ggtctgcttg atccttatgt gattatgaag aaaaagaaag actcggaaag tttagcaatt
    34861 gatattctga cttttttaac aggaatttca agtcgagacg gggagaagtt tcctgtgtta
    34921 cgtaaagcca ttcgaacggt gactcaaagt gatcaacggg ggttattaca agttattaac
    34981 gaattgcgaa aagacgggtc accaatcgcg gaaaatatcg ccgatcatat cgagtccttt
    35041 accgattatg attttgctca tttgcttttc tcagacggct cgattaccca atcgattagt
    35101 ttagataaac agctaaatat cattcaagtg gcggatttgg ttttaccgga tgcagaaacg
    35161 acttttgaag aatataccac catggaattg cttagtgttt cgatgctaat cgtcatttcc
    35221 acttttgcct tggactttat ccatagtaac cgagaaatct tcaaaattgt cgatttggat
    35281 gaggcttgga gttttcttca agtggctcaa ggaaaaacgt tatcgaataa gcttgttcgt
    35341 gctggtcggg ccatgaatgc tggggtctat ttcgtcactc aaaatagcga cgatttatta
    35401 gatgaacgtt taaaaaataa tatcgggttg aagtttgctt ttcgcagtac cgatattcat
    35461 gaaatcaaga aaaccttgga attctttggt ttggatcagg aggatcaaag caatcaaaaa
    35521 cgcctgcgag atttggaaaa cg
//
LOCUS       DAIGWC010000021        34959 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.021, whole genome shotgun sequence.
ACCESSION   DAIGWC010000021 DAIGWC010000000
VERSION     DAIGWC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.021"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            153..1859
                     /gene="efbA"
                     /locus_tag="NOB74_001067"
     CDS             153..1859
                     /gene="efbA"
                     /locus_tag="NOB74_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HCI1220269.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2017..2919)
                     /locus_tag="NOB74_001068"
     CDS             complement(2017..2919)
                     /locus_tag="NOB74_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1220270.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2916..3608)
                     /locus_tag="NOB74_001069"
     CDS             complement(2916..3608)
                     /locus_tag="NOB74_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HCI1220271.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3651..4292)
                     /locus_tag="NOB74_001070"
     CDS             complement(3651..4292)
                     /locus_tag="NOB74_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI1220272.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4330..4644)
                     /locus_tag="NOB74_001071"
     CDS             complement(4330..4644)
                     /locus_tag="NOB74_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220273.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4632..5984)
                     /locus_tag="NOB74_001072"
                     /pseudo
     CDS             complement(4632..5984)
                     /locus_tag="NOB74_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5981..6913)
                     /locus_tag="NOB74_001073"
     CDS             complement(5981..6913)
                     /locus_tag="NOB74_001073"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HCI1220274.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6910..7686)
                     /locus_tag="NOB74_001074"
     CDS             complement(6910..7686)
                     /locus_tag="NOB74_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HCI1220275.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7740..10925)
                     /gene="carB"
                     /locus_tag="NOB74_001075"
     CDS             complement(7740..10925)
                     /gene="carB"
                     /locus_tag="NOB74_001075"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HCI1220276.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10930..12006)
                     /gene="carA"
                     /locus_tag="NOB74_001076"
     CDS             complement(10930..12006)
                     /gene="carA"
                     /locus_tag="NOB74_001076"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HCI1220277.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12011..13291)
                     /locus_tag="NOB74_001077"
     CDS             complement(12011..13291)
                     /locus_tag="NOB74_001077"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HCI1220278.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13310..14236)
                     /locus_tag="NOB74_001078"
     CDS             complement(13310..14236)
                     /locus_tag="NOB74_001078"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HCI1220279.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14249..15532)
                     /locus_tag="NOB74_001079"
     CDS             complement(14249..15532)
                     /locus_tag="NOB74_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HCI1220280.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="NOB74_001080"
     CDS             complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="NOB74_001080"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HCI1220281.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16320..17231)
                     /locus_tag="NOB74_001081"
     CDS             complement(16320..17231)
                     /locus_tag="NOB74_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI1220282.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17228..17692)
                     /locus_tag="NOB74_001082"
     CDS             complement(17228..17692)
                     /locus_tag="NOB74_001082"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HCI1220283.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17697..18395)
                     /locus_tag="NOB74_001083"
     CDS             complement(17697..18395)
                     /locus_tag="NOB74_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI1220284.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18382..18768)
                     /locus_tag="NOB74_001084"
     CDS             complement(18382..18768)
                     /locus_tag="NOB74_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220285.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18915..20585)
                     /locus_tag="NOB74_001085"
     CDS             complement(18915..20585)
                     /locus_tag="NOB74_001085"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HCI1220286.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20768..21001
                     /locus_tag="NOB74_001086"
     CDS             20768..21001
                     /locus_tag="NOB74_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HCI1220287.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21100..21531)
                     /locus_tag="NOB74_001087"
     CDS             complement(21100..21531)
                     /locus_tag="NOB74_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HCI1220288.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21610..22023
                     /locus_tag="NOB74_001088"
     CDS             21610..22023
                     /locus_tag="NOB74_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HCI1220289.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22061..23209)
                     /locus_tag="NOB74_001089"
     CDS             complement(22061..23209)
                     /locus_tag="NOB74_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI1220290.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23331..23927)
                     /locus_tag="NOB74_001090"
     CDS             complement(23331..23927)
                     /locus_tag="NOB74_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI1220291.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="NOB74_001091"
     CDS             complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="NOB74_001091"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HCI1220292.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27157..27588
                     /locus_tag="NOB74_001092"
     CDS             27157..27588
                     /locus_tag="NOB74_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1220293.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27633..28982)
                     /locus_tag="NOB74_001093"
     CDS             complement(27633..28982)
                     /locus_tag="NOB74_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI1220294.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29052..30215)
                     /locus_tag="NOB74_001094"
     CDS             complement(29052..30215)
                     /locus_tag="NOB74_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCI1220295.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30344..30667
                     /locus_tag="NOB74_001095"
     CDS             30344..30667
                     /locus_tag="NOB74_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220296.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30850..32199)
                     /locus_tag="NOB74_001096"
     CDS             complement(30850..32199)
                     /locus_tag="NOB74_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1220297.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32268..33221)
                     /locus_tag="NOB74_001097"
     CDS             complement(32268..33221)
                     /locus_tag="NOB74_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HCI1220298.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33323..34513)
                     /locus_tag="NOB74_001098"
     CDS             complement(33323..34513)
                     /locus_tag="NOB74_001098"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HCI1220299.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9952 a         7639 c         6120 g        11248 t
ORIGIN      
        1 taaaaatttg gatttcaacg atagaaacac tgttttttat gtaattagtc caagattttt
       61 ctagactttt gctttactat tcggccaaat tggtttttct tctttttttc gttataatga
      121 atatacttat gaaaagaaat gaggaatgaa ccatgtcctt tgatggtgta tttacccacg
      181 cgatggtcaa cgaattgcgt gaaacgttac tatctggacg gatctcgaaa atccatcagc
      241 cttatgaaaa tgaaatcgtg ctggtgattc gttcacgcgg caaaaaccat cgattattat
      301 tatctgcgca cccaagttat gctcgtgtac agattaccca aatcgattat cagaatcctg
      361 ataatccgcc taacttcgtg atgatgcttc gaaaatattt ggatggcgct attttagaag
      421 acatcgaaca aatcgaaaat gatcgagtga tccatttcca ctttgctaaa cgaaacgagt
      481 tgggtgatct acaaaatatc atattgatcg ttgaattaat gggacgtcat agtacgatcg
      541 tcttagttaa tcgagaaact ggaaaaatac tggatgcgat caaacacatt ggaagctctc
      601 aaaacactta tcgttctttg cttcctggtg tagaatatgt tgctccgcca aaacaagagg
      661 tcttgaaccc atttagctcc gagaaagaaa aaatctttca gcggctttcc caaactgaac
      721 tagatccaaa agcaatccaa cgtcagtttc agggaatcgg tttcgatatc gctcaagagc
      781 tgaccaaaag attactggaa cgtcctaatg aaaagatggt tgtatgggac gaatttttct
      841 cagccatcag ccatcagcct attcctactt tttacgaaac ggaaaataaa gattttttca
      901 caccgattgc ttatcaggta ttgtccgaac aggcatctgc tgtaacagct tatccaacac
      961 tcagtcaatt attagatagc tattatcacg aaaaagcaga gaaagatcgg gcaaaacaac
     1021 aaggcggaga actgattcga aaaatcgaaa atgaactaaa acgaaataaa aataaattga
     1081 aaaaacgtga acaaacactc aaagaatccg aaaacgctga gaattaccgt agaaatggcg
     1141 aactacttac tacttttctg acacaagtac cacgcggcgc aaaagaagtt gttttaccta
     1201 attattatga agaagatcgg ccaatcaaaa tagcactaga tccggcattg acaccaaatc
     1261 aaaatgcaca gaaatatttc catcgatacc aaaagctgaa gaacgctgtt aagctgattg
     1321 gcgaacaaat ccaagaagcc aaagatgaaa tccaatatct tgaatctgtc ttatctcaac
     1381 tggaaattgc cggcccaatg gatatcgaag caattaaaga agaattgact tcagaaggat
     1441 acctgaaaaa gaagaactta aaaaaacaaa aacgtaagaa accatctcag cctgatcaat
     1501 acttttcttc tgacggaacg ctcattcttg ttggtaaaaa caatcttcaa aatgaccagc
     1561 tgacaatgaa gacagctaaa aaaaccgact attggcttca tgcaaaaaat atacccggtt
     1621 cgcacgtcat cattaaaagt gacaagccct cagatgaaac aattacagaa gctgccgagt
     1681 tagctgccta tttttcaaaa taccgatact ctgcccaagt gccggttgat cttgtacagg
     1741 taaagcatat ccgaaaacca aatggcgcca agcctggtta tgttatttat gaaaaccaaa
     1801 agacgattat cgtgacacca gaagaagaaa aaattacagc tatgaaacaa aacaggtaat
     1861 caatgagtgt ttctagaatc atatttgcgt actttcccac aacagcaatt agttataaat
     1921 tgtttgctac aaaaagagga gttgtgacaa aattctgtca caacccctct tttttgatca
     1981 acggtgttca ataaacagcg ttctcatctg cttttcttag ctctgctggt ccagtaaccg
     2041 agtaagctct ttgataaatc tttgagcgat ttcactgagc ggacgtttcg ccgaataaat
     2101 gatataaaat tcatttagtt cgccttctgc caaagggatt aaccgcaagt gctcgcgaat
     2161 ccctccaatc acaataccag atcctgaagc gtaagcatca gtttcaagaa cgatattcat
     2221 caaagtacct cgatcactcg tataaatcac tgtttcttga tcagggatct cgataaggtc
     2281 ttcataaaaa tacgggaaat tatttccatc ctgtgtaaaa cgaacttgag gataagataa
     2341 caattcttct ttggtgatct ctgcgtgttc agctaatgga tgtccttgcc ttaaaaaaat
     2401 atgcgttttg aattttccaa tgctgcggcc acttagctct ccttgttgta aatatcttct
     2461 gataccagct tgattatgct cattcatata aataatgccg atctcactgt gctgctcttt
     2521 gacttcttcg atcactctcg ctgttgtcgt ctccatgatc cgaaattgtt tgatctcgtc
     2581 tttgaattcc tcgagtagct gtgcggtcaa aggacctaag aaatcataat gctgggcagc
     2641 gatcgaaaaa ttgtctctct tttcactcgt tagatagtga gtttctaatg tatcaagctg
     2701 gaccaatatt ttctcggcac gatttaagaa gtcttgccct tcttctgtta aatatgcccc
     2761 tcgattcgtt cgagtaaaca gcgtgatccc taactcggtt tctaattctt tgataccagc
     2821 tgaaagactt ggctgggaga caaacatttt ctttgccgct tctctgaaac taccattgtt
     2881 tgctacagcg accacgtatt tcatctgctg aatattcatt gctcaaactc ctcgaaataa
     2941 taaatttctc ttccattcaa gggctggatt ggtcggttgt tcggtcgagc atactgacca
     3001 tcgaagggga gaagaaactc ttggttcagt tttcctacat gatccattac aaaccattgg
     3061 attggcccgc tggtaggcgg agttgtcaat gagccaatat aatggaaatg gcttttttgc
     3121 tccggaaaga acacatccgg atttacccaa tgctcatgtt tttctaagtt ccaactttcc
     3181 ccattttctt gattatacag ccaaccttcc tgtaccatta gctggtacat gacacccaca
     3241 actagattct cttttttgct gttcatatga acaaaatgaa attcaatatc ttcctgtttt
     3301 ccgttgatga tatgttcaga aggcaagtgg aaatgaatat ctgtcaaata atagcgttct
     3361 ttcttgaact ctacataact gagttggtca aaaggtacta aatgaatcgt gtttttgaat
     3421 tccttgtcag taaaccgttg cttttgataa tgaaaggaaa gcgtgtctcc ttctattttg
     3481 gtttcttccc ccttggtcaa atgaataggc gactgcaatg gaaattccgc acctctcgca
     3541 aaccaatcac ataaactcgc ccaattttcc ggacctttgt ctccagaata gccccattcg
     3601 acatccatat tctttttcaa ctatacttcc ccctgcatct catatcattt ttatttttct
     3661 tctttcttta caatcgttga gacggtttct aaaaacgcct cttttccata aaattcctgg
     3721 ttcaatagtt ccggaaatat ctctttaaag aaatactgaa cagaaggccg atgttcaaag
     3781 cttttaatcg tagtcactgc ctcaatgaac atctccttat aaactttttc cgggttattt
     3841 ttgatgattt catcaaaaga ttcataaaga aggtcaacct tatctgaaat ggctaatagt
     3901 tctccttcta cggtttcatc ttttccttcg aacaaccgac ggcgataaac ttcttggaac
     3961 tcagctggaa tctcttggtt gatgaattcg tccgtcatct tttcttcaac tgtttgcagc
     4021 atccctctta actctttgct tgcgtatttc accggcgttt tgatatcacc aataaaacgc
     4081 tctgtgtagt catgattcaa tgatttttca tagagcagtt tccaatcgat cggttgtcca
     4141 ttcgcttctt caatgtctcc tagaacttgc gcaatagatg ctacacgata cgaatgtgct
     4201 gcaactgtat gctctgtata tttaaaaaat ccaggtgccc ttgtgatcgt ctctaaattg
     4261 ttcaatccta aaataaattc attcaacccc ataaaagtta cctccctttg agatttcttt
     4321 ttccgaatat catatcatta aataactgat attcgcaaca tttccgctct ttaccatttt
     4381 tgaaacagct cccttaccaa aaaatagaga aaatctatat ataatagaaa aaagagaaga
     4441 gattattctc ttctttctgc taaccagtct tagaaaaatg aattttaaaa aaatcaaaaa
     4501 ctgatcacga tagaagtttc ttttcatacc tgatgaaaag atgcttctcg caatcagttt
     4561 ttggattttt gctattccaa ttgatgattc tggagacaca aatcggattt ctctatcttc
     4621 atcaagcgcg cttaaatctg ccaattttca ggatcttttt tccattcttt tagcagagtt
     4681 aattcttgct catcgatata acgatcttct aaagctgctt caatcaatac agaataattg
     4741 gtcaacgtca taagagggat ttcggctttt tcgaaatttg cttttccttt tggcaactca
     4801 tacgtaaaga tagccgcaac accaaggata tccgcacctt ctctttttgc tgcttcagct
     4861 gcttccaaga cacttccgcc tgtagaaatc aaatcctcga tcacaaccat cttctgacct
     4921 tcaaatatac gtccttcgat ttggttacct ttcccatgat ctttcgcctt acttcgaata
     4981 tagaccattg gcaaatccag tatttccgct acccatgcgg catgagggat tcctgctgtt
     5041 gcagttccag caatcacttg tacttcaggg taagcttctt tgattttgct tgctaatcct
     5101 tttgcgatct cttttcggac ttttggatag ctcatcgtga ttcggttatc acagtaaatt
     5161 gggcttttga ttccacttgc ccatgtaaaa ggattacttg gatttaaaaa tactgcttca
     5221 atttctaata agtcttttgc gatactttgt tcaacattca ttttaggtta gctccattct
     5281 gtttgaatcg tttgatatgc tttataagga ttagttgact gagtgattgg tcgacctata
     5341 acgataaaag ttgagccgat cttttttgcc tgagaaggtg tgactactct tgtctgatct
     5401 cctgcgactg ttccttctgg tcttataccc ggagttaagc aaacaaattc gtctcctgcc
     5461 atttctttga tcgcttctac ttcccaagca gaagaaacca caccatctaa tcctgctttt
     5521 ttggcacagc tagcataatg gatcacactt ttttctaaag aaacttcgat tagttgatcg
     5581 gcatgcattt cttcttcact tgtagaagta agctgagtga tagctagaag tagcggacgt
     5641 tttccacctt ctggagtccc ctcttctaat cctcgcattg ccgcctccat catacgaata
     5701 ccgccagcgg catgaacaca ggtgagatca acaccaagct ttgccaatcc ccgcattgct
     5761 ttttcgaccg tattcggaat atcgtgaagt ttcagatcta aaaatacatt atgaccagcc
     5821 tcttttagat aacgtacgat ttcaggtcct tcttggtaga acaattccat tccgattttc
     5881 acaaacaatt tttcttcttt cgggaaaaat cgaagaaagt cttctacctc ttgcctagtt
     5941 gaaaaatcta atgcaataat tggtcgttgg tctagttgat tcatcgttca cgttcctctc
     6001 tcacttcttt gattaatctt tccagcgatt cgatgcctag ttcgctcatt cgcacaggga
     6061 gctctttaat tagtttagga cagatatacg gatcggtgaa attcgcggtc cctatagcta
     6121 cagcacttgc tccagccata aacatctcaa gaacatcatc cactgtctgc acgccgccca
     6181 tcccaatgat tggaaggctg gatatacttg ctacttggtg aatcaaacga atagcgacag
     6241 gcttgattgc tggtccggag agtccacctg tttgattggc taaaatcggt tttcttgtct
     6301 taaggtcaat ccgcatacca agaagagtat tgatcatcgt aaacccatct gcccctccag
     6361 cttcgattgc ctgagcgatt ggaacgatgt ctgttacatt tggggacaat ttgacataga
     6421 caggaacaga agaaactttc tttactgctt gtgttaattg aaaagcaaca tcagaatctg
     6481 ttccaaaagc aattccgcca tgtttgacat ttgggcaaga aatgttcagc tcgattgctt
     6541 tcacatttgg tgcttcgcca attttgctac aaacttctac atagtcttct tcacaagcac
     6601 cagcaacatt tgcgatgatg ggtaactcat tgtactcctc taattctgga agaagtttat
     6661 gcataacaac gtctagacca ggattttgca aaccaattgc attcaacatg ccagatggtg
     6721 tttccgccac tcttggcgtg ggattgccaa agcgggcatt tggagtcgtt gccttgacca
     6781 tgatcgatcc aagctgattc aaatcatagt attttccgta ttctttgcca aaaccgaaac
     6841 agccgcttgc cggcatgata ggatttttta attctaggcc aggaagtttg accgctaaag
     6901 gattctcatt catataatta cctctcctat tttaaaaatc ggtccttcgt cacaaacttt
     6961 cacacttttt gttcctgttt catcttccgg cgtatgacaa acgcaagcat agcaagcccc
     7021 tatcccacat gccatgcggg attctaatga taactggaca ttttgatgcg aagaaaacag
     7081 ctgttccact gtcttcaata acccgtttga accacatgca aaaacagctg taggttccgt
     7141 cttcgttcct aacaataaat taccgacatt tccgtgcata ccgtatgttc catcgtcagt
     7201 agcgattctt gtttctccta gacgattaaa ttctttttca taataaacga cttcatgtgt
     7261 ggcaaaacct aaaaaatgcg ttggcttaat tcctttttcg actaactgtt ttgataactc
     7321 atatagagga gggacaccga ttcctccacc gattataaat acttcgtctc ctgtatgaag
     7381 attggacaaa tcaaaaccat tgcctaaagg acccatgaca tctaaatggt ctccggcaga
     7441 aagagtagag aagactctag tcccctcacc ttccacccga taaatgatac ggcaagtatt
     7501 tgtttcgtgg tcgatatgat tcaagctaat cggtcggcgt aatagcaagt ctgcacgcgg
     7561 cacgagaata tgcaagaact gtcctggttg ctgcatttct tttactagat cacctttcaa
     7621 tgtcatttca aaaatctttg gtgccagctg tttttgctga acgatttcca tcatttcttg
     7681 tttcatctgt cccctcctgc aacggttttt cgtctttttg tcttaacatg tgctcgccgt
     7741 taaatagggt tagttgaaaa agcacgggat tccatcactc gaacgatcgc atctgctgtg
     7801 tctaaagaag taaacaatgg aataccatgt tcaactgctt ctcttcggat gatgaaaccg
     7861 tctttagaag catttccccg atctttatca atcgtattga caaccacttg tgttttacca
     7921 tctcttatta agtcgactac atttttttct gctgcttcct cagaaatttt cgctactgtt
     7981 tcaacgacca gaccattttt ttcgaaataa gcagctgtat gtttcgttcc tatcagacta
     8041 tagccaattt ctgtaaaacg tttagctaat tctagtgctt cttcttttgt ttcgtccgca
     8101 atcgtaaata atacggctcc atattcaggc aagtgtaatc cagaagcttc gaatgccttg
     8161 tacaaagctt tgtctaattg tctgtcagat cccattactt ctccagtcga tttcatttca
     8221 ggccctaagt aagtatcaac tttctgcaat ttcgtaaaag aaaagacagg tgctttaaca
     8281 tgaacttctt ttgtttctgg ataaagtccg ttttcataac caagtgtctt tagtttctct
     8341 cccaaaatag ctttcgtcgc aatttgtgcc attggaattc ctgtcacctt acttaagaat
     8401 ggaacagtcc gacttgctcg aggattgact tcgatcacat aaacctcatt ttcatggatg
     8461 acaaactgga tattcatcat cccgacacaa ttcaaaccta atgctaagcg gatcgtgtaa
     8521 tcttcgatcg ttttcttgat cgattcagat aatgtttgag gtggatacac agccattgaa
     8581 tcccctgaat ggacaccagc acgctcaata tgctccatga tccctgggat gagtactgtt
     8641 tcaccgtcac aaatcgcatc cacttcgcat tcaccaccaa gcaagtaacg gtccactagt
     8701 actggatgtt ctggagatgc tttcacagca tgttccatgt aatcttctaa atctcgctgg
     8761 ttttcaacga tttccatcgc acgtccgcct aatacatagc ttggacgaac aagaactgga
     8821 taaccaattc tcgaagcgat aaccacggct tcttctttac ttgtagcagt atcccctaaa
     8881 ggttgaggaa tatccaactc tttcagcgct tgctcgaata aatcacgatt ttccgcacga
     8941 tccaagtctt cgatcgttgt ccctaagatt tttacaccag cagcagtcaa aggttcggct
     9001 aagttgattg ctgtctgacc accaaattga acgattactc ctatcggctg ttctagctcg
     9061 atcacattca tcacatcttc gaaggtcaat ggctcaaaat ataatttatc cgaaatagaa
     9121 aagtcagtcg aaactgtttc aggattgctg ttcatgatga ttgcttcgta tcctgcctgc
     9181 tggattgctt tgacagaatg cacagtcgca tagtcaaatt caaccccttg tccgatacgg
     9241 ataggaccag atcccagtac tagaattgag ggcttttctg atcgtgaact ttcattttca
     9301 tattcatagg aactataaaa ataaggtgtt tttgattcga attccgctgc acaagtgtca
     9361 accatcttat atacaggaat caaatcattt tcttttctca tctggcgaac ggcttcttcg
     9421 tttatttccc acagctccgc cacttttttg tctgtaaaac cgttttgttt cgctgttttc
     9481 aatatcttgt catccaacgg ctgctgtttc aactgctgtt cgatttctac gatatgcaac
     9541 agtttatcta aaaagaataa atcgattttt gtcaaatccg ctaattcttc tatggtgtac
     9601 cctcttctaa tagcttcagc tacataaaac aggcgatcat cttgtgctcg aaccactttt
     9661 tggattaggt catcgtccgt gatgtctgcc aactcaggaa gttcgatatg gtgtgtaccg
     9721 atttctaaag aacgcacagc tttcaataaa gactcttcga tattccgacc gatagccatc
     9781 acttcaccag ttgctttcat ctgcgtgcct aaaagccgtt ctccgttttc aaacttatca
     9841 aacggccagc gaggaatttt agctacaaca taatctaatg caggttcaaa ttctgcaaaa
     9901 gtcgttcctg taacaggatt tttcatttcg tctaatgtta atccaagcgc tattttagca
     9961 gctagcttag cgatcggata gccagtcgcc ttacttgcta acgcagatga acgagaaaca
    10021 cgcggattga cttcaatcac ataataatta aaactatgtg gatcaagagc gagttggaca
    10081 ttacagcctc cctcgatctt aagtgctcga ataatcgaaa gagaagcatc acgaagcatt
    10141 tgatattcat ggtcagacaa tgtttgacta ggggcaaata cgatagaatc acctgtatgg
    10201 atacccaccg ggtcaaaatt ttccatattg cagacaacga ttgcattatc agccgaatct
    10261 ctcatcactt catattcaat ttctttaaaa cctgcaatac ttcgttcaat caaacattgg
    10321 gtagcggggg aaagacttaa tccattttct gatacgatac gtaattcttc ttcattttca
    10381 cacatacctc caccagttcc gcctaaagta aaggctggac gaacgatgac aggatagccg
    10441 attttatttg caaaatctac agcttcttct actgtattga cgatttcaga ctcggggatt
    10501 ggctgattca attctttcat caactgtttg aatagatcac gatcttctgc ttgatcgatc
    10561 gcagaaagct ttgttcctag aagttctatg ttcaattctt ctaaaatacc tgatgctgcc
    10621 agctccattg ccatattgag gcctgtctgt ccgcctaaag ttggaaggag agcatctgga
    10681 cgctcttttc gaagaatcct tgatacaaat tcaagtgtga tcggttcgat atatacttga
    10741 tctgccactt ctttatccgt catgatcgtc gcaggattag aatttactaa aaccacttca
    10801 tatccttctt cttttaaggc aaggcaggct tgtgttcctg cgtagtcaaa ttctgcggct
    10861 tgaccaatga tgatcggacc agatccaatc accataattt tcttgatatc tgtacgtttc
    10921 ggcatctgtt tactgctcct ttcctgcgtc catcatttcc ataaattcat caaataaatg
    10981 tagtgcatca tgcggaccag gggcagcatc tggatgaaac tgcacactga aagcgggata
    11041 atctctgtgt ttgactcctt ctactgttcc gtcatttact tctacatgag ttacgatgag
    11101 tttttctgga tcaatcgtgg cttcatcgac tgcatagcca tgattttgag aagtaaaatc
    11161 aattcttccg gtcgctactt ctcgtaccgg gtgatttaat cctcgatgtc cgaatttcat
    11221 tttataggta tctgcaccgt tggctaaagc aaataactgg tgaccgagac aaataccaaa
    11281 aatcggtact tttccttgga tttttttgat catttcgatt gcttctggca catcttttgg
    11341 atcaccaggt ccattcgtca gcatgactcc gtctggtgat agcgctaaaa tcgtctcggc
    11401 atctgtgtta tagggaagta ctgtgaggtt acagtttctt ttactcaatt ctcgtaaaat
    11461 actatgtttc aagccgaagt caatgacaat gactttccga cctgttcctg gacttggata
    11521 aggtttgtta gttgagactt gctgcacttg attggttgct agaacggttg ctttcagctg
    11581 atcaaatgca tgttcgaagg aatctccagc atcaactata ctagctttca tcgttccgac
    11641 ttcacggatt ttgcgagtaa gggcgcgcgt atcgatacct gatattccag gaattccttt
    11701 ttgtttcaaa aatgaatcta gcgtcatttg gtttcgccag tttgaagcta cacgtgcatg
    11761 ttcttttact actactcctt tgcatgttgg agaaatcgat tcataatcat ctctatttac
    11821 cccataatta cccaccatag gataggtaaa tgtaatgatt tgaccgttaa aactttgatc
    11881 agtgatagtt tcttgataac cagtcatact tgttgtaaaa acgatttctc cgaagacact
    11941 agcatctgca ccaaaagcct ttccttcgaa aactgttcca tcttctaata taagcaaacg
    12001 ttccatactt ttattctccc ttctgccaca caagttttcc gttgacaaaa gtcatttgtg
    12061 tttcgccttt tactttccag ccgataaaag gtgtattctc cccttttgat aaaaagtctt
    12121 ctttatcgat cgtgcaagtt tgtgtaatat caaaaactgc tacatcagcg ggggcaccaa
    12181 ccgttagcgt tcctgcattc aaaccaaaaa tctcagccgg tttaactgcc aaccaattga
    12241 tcacttgttc caacgtgaat cgaccagttt ctacaaaatg agtatagatc agttgaaacg
    12301 ctgtttcgct tcctacgata ccaaatggtg atttcatgaa actttggctt ttttcttcta
    12361 atccatgggg ggcatggtct gtagcgatgc aatcgatcgt accgtcaagc aagccttcga
    12421 tcaaagcttc tctgtcctcc cgtcctctta gcggcgggtt cattttccaa aagccgaaat
    12481 cttcgggaat atcttcgtcg atcaaaataa gatgatgggg tgaaacttct gctgttacgt
    12541 ggattcctgc tttttttgcg tctctgatta cacggacact ttctttagta gaaacatggc
    12601 aaacatggta atgaacacca gttgcttcag ctagcaacag atctctagca atttgagaag
    12661 actcggttac gcttaagatc ccgggaagac caagttcttc tgccttcttg ccagcgtgca
    12721 taacgccgcc aaataataaa gattcatctt ctgtatgggc tactagggct ttattgtttt
    12781 ttgcagcttc tttcatagcc agatacatcg tcccagctgt ttggacacct acaccgtcat
    12841 ttgtgaaagc aaaagcacct tcttcaatca gtgcttcttg atcaactaat ttctcacttc
    12901 gcagattttc tgtgattggc gcatactgca ataccttcac aactgcatct tttctaatga
    12961 tgtcatatac ttgtctcagc ttttctgccg tatcaggtac aggatttaaa ttcggcatcg
    13021 cgcatacagt agtgaaaccg ccacgagcag ctgagcgagt cccagcttcg atcgtctcct
    13081 tgtatgtaaa tcctggctct ctcaaatgaa catggacgtc cactaaacca ggtgtgatca
    13141 attgtccctt tgcatcaaac acttcatcaa attcggcttc tgagaatcct gtaccgattg
    13201 ctttgattcg cccatcttct atccaaattt ctgctggtgt cgtcatattt tttcgtgtat
    13261 tgatctgacc gtttttaatg agtgttttca ttttttcatc ctcctataat tacgcttttc
    13321 catttagcac tgcttctaag attgccattc tgacgaatac tccattgctc atttgctgaa
    13381 cgatccgcga ctgtaatcct tccactaatg aatcagctaa ttctacatca cggttaactg
    13441 gtgctgggtg cataatgatt gcatgttttt gcaacttctt cgcacgctca actgttaacc
    13501 catgttcctg atggtagcct tcttttgaga aactttcttt tccatcatgg cgttcgtgtt
    13561 gcacccgaag catcatcatg acatcaactt gatctagtag ttcatccaat ggcatataat
    13621 gtccgtacac ttcgaattca tcgtcgtacc attctctagg acctgagaag aatacttgtg
    13681 cgcctagacg ttttaacatc tgcatattgg atttagctac gcgagagtga gtgatatcac
    13741 ctacgatggc aactttcaga ccttcaaaat gaccaaattc ttcataaatg gtcatcaaat
    13801 caagcaagca ttgggttgga tgctgtccgc ttccgtctcc tccattgata atcgaacact
    13861 ggattgtttt actttgtatc agttcgtcat aatagttctc atcaccatga cggataaccg
    13921 ctacgtctac gcctaatgct gacatcgtca gtactgtatc gtatagtgtt tccccttttt
    13981 ggacagagct tgtgcttgct tcaaattcaa tcacttctag ccctagtttt ttctccgcta
    14041 catcgaagct tttatgtgtg cgagtactat tttcgaaaaa gaggtttgta gcaaagtact
    14101 ggcgcttttg cggagtccaa ttagcacctt gcttgaattc ctgccctctg cggatcaagc
    14161 ccataacttc ttgatcagta agtgcctcaa cggtcaataa atgctttaag ctgatacgtt
    14221 ctgatttgat gatcataatg tttcctcctt agttttcttc gcttcgtgaa gtttctggta
    14281 agataagatt taaaatgatg ccaagtacag ttgctaatgc cattgccgac aatgtaaatg
    14341 tgcctacttc aaagacgagt ccgccaattc ctactactaa gataactgaa gcaatcaaca
    14401 gatttttctt tttatcaaaa tcgattttgt tctcgattaa aatcttcatt ccacttgcgg
    14461 caattactcc aaataagata aaactgattc ctgagatgac tggtccaggg atacttaaaa
    14521 tcaaagcgct taattttcct acgaatccta aaatgactgc aaatactgca gctccaccga
    14581 tcacaaacac gctatggaca cgtgtgatag ccagaacacc aatgttttca ccgtaacttg
    14641 ttacaggagg acctccgaca aaggctgcca cgatttgtgc taatccatca cctgtcaacg
    14701 tcttatgaag acccggttct tcaaagaaat tacgtttagt tagtttattc aataccataa
    14761 gatggccgat atgctctgtc atcgtcacaa aagcgatggg tgccattgtt gtgattgctc
    14821 caagatatag ctttggttca tattgtacaa agggaatctc aaagttagga acagcaaacc
    14881 aggcagcgtc tacgattggc ttagtatcca cgattccaaa cagcaaggct acgatgtatc
    14941 cgctaataat acctagtaaa atcggaatca atccgagaaa acctcttagc cacatgttga
    15001 agaaaattgt taatcctaat gtgatcagcg ctacagcaat atacttgaaa tcatacgtgc
    15061 cctgattata catagcattt gttgctgcat ttgccgcaag tcccaacccg ataaccatga
    15121 tgactggacc gacgacgatt ggaggcaaga ttttatccag ccatgctgaa ccgatctttt
    15181 tgatgatcag cgcaacaatc aaatagacta atccagttgt gactgctcct tgtgcaatcg
    15241 ctggataacc atctgttttc atcaaaagct gcatcgctgc aatgaaagcg aagctgcttc
    15301 ctaagtacgc aggtatcttt cctttagtag taaataagta caccaatgta cctagtcctg
    15361 aactgactag cgcaatacct ggatcgatac ctactaagat ggggactaac acggttgctc
    15421 cgaacatcgt gaacaagtgt tgtaaactta atcctaccca atgtcctggg gttgggcgat
    15481 cgtggatatc taacaccacg tcatcattat gaaatccttt tttctccgac atgtttctct
    15541 ctcctctaat cttcctcttt caaaatcatg atgcgatctt gtccatcaag ctcttgcatc
    15601 tctactaaaa tctcttccgc ccgagatgtt ggaatgttct tcccaacata atctgcacgg
    15661 attggcaatt ctcgatgccc acgatcgacc aggactgcta atgaaatttt tcttggtctg
    15721 ccaaaatcca ttactgcgtc cattgctgct cgaatcgttc gtcctgtata caaaacatca
    15781 tcaatcaaaa taacttcttt tccttctaag gaaactggga tgtcagaaga atgaagttcc
    15841 ggttcttctg gattttcttt tttgtcatct cggtataaag tgatatccag ttctcctaca
    15901 ggaatatcga tatcttctag ctgcttcagg cgttcggcaa ttcttgatgc aatgtagatt
    15961 cctcgtgttt tgatacctac caatacgata tcttggatac tatggtttct ctcgataatc
    16021 tcataagtaa ttcgagtcaa tgctcgcttc atggttacct gatctactac ttcttttgct
    16081 tgcattttca ttccccctac ttttttgcat aaaaaaactc ctgccctaag aggacaggag
    16141 gaatgtttag actgagcgta tactgataca ctgatagcta tactatgtca atgagcaatc
    16201 tacttatggc gcaccatacg tatccttgct cccacccttc ttagcctcac gggactaaac
    16261 ttaaaggaat tctattaagt tttatgcttt cgttgttaat tactataccg ttatctaaat
    16321 taaaatgcaa tgttttttct taatttttct aaagtttttt caaaaacttc tggaagaggt
    16381 gcttcaaaga tcatcttttc gtttgtagtc gggtgcgtaa aacctaacat ttgcgcatgg
    16441 agaaactgac cattgccttt caaagttttc ttcggtccgt atactggatc tccagctaac
    16501 ggataaccga tatacttcat atgcacacgg atctggtgtg ttcttccggt ttctagtttt
    16561 aattcaacca gagtaaatcc ttcgaaacgt tccaatacag taaaatgtgt gacagccgac
    16621 ttcccatctt ctcttatcgc ctgcattttc cggttttcct tcgaacggcc gattggcgca
    16681 ttgatggttc ctttttcgtg aggaatctct ccatggacta aagcaacata tttgcgcaaa
    16741 gaggtcttat cttttaattg ctgagctaat gattcgtgtg cctggtcatt tttggcaacc
    16801 attagcagtc cggaagtatc tttgtcgatt cggtgaacaa tacctggacg aataacgccg
    16861 ttgatcgtag aaagatcctt gatatggtac atcagcgcat tgaccattgt gccatgcgta
    16921 tgacctgctg aaggatgaac gaccattcct tgaggtttgt ttatcaccgc tacatcttca
    16981 tcttcgtaaa cgatcgtcaa cgggatattt tctgggacca catctaatgt ttctggttcg
    17041 gggatcaaga cagtaatctc gtctccttgt tttactttgt aatttgcttt gactggctgt
    17101 ccattgacag aaaccgctcc atttttcagc cacagctgaa tttgcgaacg actgtaatcg
    17161 gtgaataaat tagtcaatac tttatcgatc ctaccagatt catggtgaat cgtcgtttta
    17221 agttctgtca tttttttctt tgatcctttt catctaaaat aatataaatt aacatacaaa
    17281 tcactccaca tacaagtgtc acatctgcta cgttaaaaat cggaaagctc ataaaatctg
    17341 tctggaacat atctactaca tagccaagac gaatacggtc gataaaattg ccaatcgcac
    17401 cagctagaat caaactcaat ccaatcatga accagcgatt acctttttca cgatttttaa
    17461 tcatcaatgt gagaatcaca acgactgcaa tgagtgtcac tatagtaaag aaccacatct
    17521 tcccttctag catactccat gcggctccag tgtttcgaat atgattcagt gacaaaatac
    17581 ctggtataag atttttcgtc tctccaagcg ctagattatc agtgatccac catttgacca
    17641 actgatccac tcctactagc aaagcgctga atatccaata aataattaac aaaaaatcaa
    17701 tccttttcta tttgtttata aatatcacga ggtcgtacga tcccgagcag attaccatcg
    17761 ggattcccat ctttagtgat aagtacggct tccaaagtcc cttgctcacg aaacatcgct
    17821 tcaacctcgt aaatatgtgt tttagctgga acaaaatgat aatttgtgta ctttccgttt
    17881 tggatgatca aatccaacgc tcgtttattt gttaaatcaa ccggaccttt ttggctttct
    17941 tttgctagcc aaaacccgat attacgtaaa gtaatcaatg ctacaaattt tcctttattg
    18001 tataacggaa attgtgaata ccttttttct gctactatct ttaacagttc aagtaacgga
    18061 agatcttgtt caaaacctgt tacacgtttt gcaaatcgag gcagcacggt ttcaggctga
    18121 atcagttctt gttcgatcag ctggattcgc ttgactgtcc aatcatttgg ctctgcaatg
    18181 acaaaatcga ctgcgatccg atcatggacg atcgcattcc ttaactgagc aagctgtaaa
    18241 agatcatctt cgtattttct gatcattaat tgttttcttt gagctaggcg tctgacaagt
    18301 tcggtaaatc ccatatttcg tgcatttccc atctcgtctc tcatccattt ttcgattcga
    18361 ttgaaactga ttaaaaaaag atcagagttt gccataattt tcctccttga tcaaatatgc
    18421 ccggtttttt atatagaaaa agaacgcaat caacacaata actgcaaaaa aactgaaaaa
    18481 taaattttgt aggaaaacgg cccccaaccc agttgctaga aataaaaacg gatagatttg
    18541 aagaatcaag taattcattg tgatcacata agcaggcttt gcttctttca ctgtataaac
    18601 ggggcttttt agccaataaa aggtgacctg catcgtaaag ggcacttcca gatcaagcgt
    18661 tatcttttgt tcatgactga gaacactgcg tttttcattg ttgattctta gctgaatcga
    18721 gctacccata ccgtaaaaac cggtttttct tataaatgtc gttttcatca taccctccta
    18781 ttatgcttta gtatagctca aaatacaata aagaaaaaga atgatcctag tgtaaacaaa
    18841 attaattccc tatcgtctaa aaaaagaagc tgtagtcaaa atacagctcc ttcgatggta
    18901 gattataatc aagcttaaaa caatcccaac acttctccgt catttgtcac gtccatattc
    18961 aatgcagcag gttttttagg caaaccaggc atcgtcataa catctccagt caaggctact
    19021 aaaaatcctg cccctaattt tgggatgatt tcgcggatcg tgatggtgaa atcttccggt
    19081 gcacctagca gtgaaggatc atcagaaaat gaatactgtg tttttgccat acaaatcggc
    19141 agtttgtccc atccattctt cgtaaactct tctatttgtt tttgcgcttt tttgctgaaa
    19201 acaacaccat ttcctccgta aattttcttg acgattgttt ctgtcttttc ttgtatcgtt
    19261 tcttctaggc ggtataatgg cttgtaatta gcttcttttc tatcaatcaa tcgtactaca
    19321 gcttttgcta aatcaacgcc gccttctgct ccatctgccc atacactcgc tctcttggca
    19381 agaatcccct gattttcaca caagtgctcc aacagtgtga gttcattgtc tgtatctgtt
    19441 acgaattcat tgattgcgac gatcacaggt agctgatatt gttccatatt acgtatatgg
    19501 cgctttaaat ttgcaaaacc tactttcaaa gcatcaagat tctcattttt aagttcatct
    19561 tttttcattc cgccatgcat tttcaatgca cggacagtgg cgacaatcac cacagcatcc
    19621 ggcgcttttt tcaagttagg tactttgata tctaaaaatt tctctccgcc aagatctgca
    19681 ccaaatcctg cctctgtgac aacgtaatct gctaatctca atgctgtctt ggtagctaaa
    19741 atactattgc agccatgagc gatattggca aacggtcccc cgtggacaaa agctggtgtt
    19801 ccgtaaattg tttgtacaag attcggcttg attgcatctt tcagcagtaa tgccagagcg
    19861 ccttctgctt tcaagtctcc agcagtcaca ggctgacggt caaatgtata gccgacaacg
    19921 atccttgcaa gacgagcctt taaatcttca aggtctgccg caagacacaa gatagccatg
    19981 atttcgctgg caactgtgat atcaaaccca tcttctcttg gaacaccttg gattggccca
    20041 cccaagccaa caattacttt acgcagttca cgatcattga gatcgactac ccgtttccaa
    20101 atcactcggc gggcatcgat gttcaattca tttccttgat gaatatgatt atctaaaaga
    20161 gcagataatg cattattagc tgttgtgata gcatgcatgt caccagtaaa atgcaagttg
    20221 atatcttcca taggcaatac ctgtgcatat cctccgcctg cagcaccacc tttgattccc
    20281 atcacaggac caagtgaggg ttctcgcaat gcaataacag attttttatt gattttattg
    20341 agcgcgtctc ctaaccctac agtgatcgtt gactttcctt cgccagctgg tgttggattg
    20401 atggaagtaa ctaagatcaa atgcccctca gcgttatcct ttgatcgatt gattccagaa
    20461 aaattgattt tcgccttata tttcccatac agttccaaat cgtcttcctt aagatctaat
    20521 ttactagcca cttcaacaat cggttctagc tctgtttctt gtgaaatttg cagatcattc
    20581 ttcatttgat tacccctttt cacgaacttt attcaacaaa atatcttctt tgttaagata
    20641 tgccaattat accttttttt attcagaaaa aaaacataaa attacaggtt tttaatttat
    20701 ttgacgtact tataaatact ctttataatg aaggctatga tcagacttta gaaaggtcgt
    20761 gagtgctttg accacaggaa ttgtaaaatg gtttgacaac aaaaaaggat acggctttat
    20821 cagttatgat gacacagaag aaatttttgt acattttact gcgattgaag aagagggatt
    20881 caaaactttg gaagaaaatc aagtggtcga atttgagatc atcgaaggga atcgaggaac
    20941 acaagctgcc catgtcaaga aaggcaacgt tcagactacc gatactagta tgcatgaata
    21001 gataaacaaa tagagtgaga cgctaaacgg gatgaaccgt acgtctcact cttttctttt
    21061 cctgtaaaaa ttcgtttttt taggttctga tttttaaaat tagctttttc tttttttcgt
    21121 ataaggataa ggaattgatt ctgatttggg tccgtttttt tcaaaatgat caaaaaggac
    21181 tacttgatct ttttttcgca tcatgaaaac agatggggct ttctcatctt gcaacatcat
    21241 ttgcacccca gtattagttg gcgtcaaaga tcgaatctgt ccgacagata tttctcggtc
    21301 tttccaaaaa gcagcataac gtataatcac agagtttgat tttaaaataa aagaacgccg
    21361 caaacctaga aatagaaaaa caagaaaaat acctaaaaca aaattgcttt tccaataagg
    21421 acctgtgttt tctaaagaaa gaatcagact aaaaaacaga atgatcaagg tcaatgacca
    21481 atagatgatc gtatgtgcca gttcaggctg ccatcgaata ttttttttca ttctctaacc
    21541 tctcaccgat tcagtaatga tataatctta ccataacatt agtttgaaca aaaaggagaa
    21601 tctcttttta tgttaaaagt atacattgat gcctctacaa aaggcaaccc tggtcctagt
    21661 ggaggtggaa tcttgattgt ctatcaaggt aaacaagaac agctatctat cccgctttct
    21721 atagggacaa accatcaagc agagttcgaa gtctttttaa aaactttaga atttctaaag
    21781 aaaaacgact tacagaatga aacgattttc tgtttttcag acagcaaaac actagtttct
    21841 acggtcgaca aaaacgcaac gaagaacgag ctcttccttc cctaccttca aagaatccaa
    21901 gaacttctat ccgaattttc tttattgatc ctgcaatggt tgcccgaaaa caaaaataaa
    21961 ggagcagata atcttgcacg tcaggctctc cataaacaat taaaagaaaa aaagactctt
    22021 taaattaaaa actttaagga gtctttttat agtttctcat ttaatataaa agataattgt
    22081 gatcaaacgt aatttccaat tggtaatctc cgattttttc ttctatttga ctacgtaaga
    22141 ttctttctag ttctgtatca acaaactgga atttctcagg gaccactaca tcaaattgca
    22201 gcgtttttcc ttgatgaatt actctaaaat catgaatatt aagccctgta cctgtttcaa
    22261 gaagaatttg ctttaactgc cgcaagatat tatagtattt ttcgttatca acaggcattg
    22321 gatccaagtg acagacaagt tccacatcca aagacttttt aaagtctttt tctatcagat
    22381 caataatctt atgagccaca ttcaaattca ttgattcatc tacttcgatg tggactgatg
    22441 caaagcgttt attgggtcca tagttatgca ccaataaatc atgatagcca agtatatcat
    22501 cgcaagcatt taaatgctct tccatttctt caatctctgc tggcgttggg cgacttccta
    22561 atagttcgta tacaaaattt cgaagcatcg tcaatccact ataaaggata tataatgcta
    22621 aagcaaaacc tatatatcca tcaatacgcc atccagttac ccattcgatt gctgctgaaa
    22681 gcaatacagc cagtgtagta aagacatcat tataactatc tgttgctgta gctctcaatg
    22741 tttcagaatc aatggattgc gcaataacct gatacatttt gccttgtgca aatttcaaaa
    22801 agatggaaat gattaggaca aaaaagacga tgggtgttaa agagacattt tctggatgga
    22861 tgattttttc agcagaagac tctaaaaatt gaaatcctac ataagtaatg atgatcgaaa
    22921 caaataaccc actgatatat tcgaagcgtt cgtgtccata aggatgttcc tgatctgctg
    22981 gctttgcagc aattttaaat ccgatcaaag tcaatatgga tgaagcagta tctgatagac
    23041 tgttcactgc atcagccata atggagacac ttcctgaaaa aagcccgatc attagcttag
    23101 agacaaacaa gatcagattc gtaaccaatc ctaagatacc cgctagtact cctttttttg
    23161 tccgctgttg cggtatttgt ttcttttttt cttcttgttt cttagccaag ttttttaccc
    23221 cttctagttt gcttgttgct caggtaaaaa gatggagagg acgattgttt tcctctcctc
    23281 tcttcctttt tctatctatc gtgcgtccta ttactattaa aagatggtca ttattctggt
    23341 ttcaacggtg ttgctgcaaa taacgctttt gctagtaatg gtgttatgat tcccgcacct
    23401 attgcttctg gtatcccatt gattgctgca acccctgcta aggttttaaa taaaagagca
    23461 gagtctacac cataggcatc tgccgttgca cctgtataaa ataatcccat gaatcctaac
    23521 actaagactg tattgaccaa tgaacccagt acccctgcaa aggctgagct gatcgttatt
    23581 gatttatttt tttgataaat ccagtggaaa accaagcctg ctactaagcc aacaagtact
    23641 ctgggaacta ccgagataat cggattcgtg aacactaatg tatcaaatgg cgttgttggc
    23701 atggcatagg cacgaacaat tgtagcgatt ccccaaaaca agccaatcac catgccatct
    23761 tttgggccta atactactgc agcaataatt actgtgatat ggataattgt taaactaatg
    23821 aatcctaatg gaataaaccc cagccaagga accatcgctt gtacgatgat gattgctaac
    23881 aagatcgcac gtaagactag tcgaaaggtc ttatttctac tattcatttt ttcacccctt
    23941 tttatttata ctaatcgtaa aaatttctgt cactttcgtc aactaaagac catccgaatc
    24001 cgaccatttg attagatgcg ccatccaatt gaaaaaagta tgagggcaag acttgtttgt
    24061 cttcgccccc ataatcatgt ttcgttcaat gtttgaactt ttgtttttct gtcaaacgta
    24121 aacgccctat tgttgcgcaa cccattcttt cgcagcttta agtgcatctg gaataccagc
    24181 aggatttttc ccgccagctt gtgccatgtc tggacgtcca ccaccgccac cgcctacttt
    24241 cggtgcgatt gctttaatca agtcgccagc ttttagtcca gcttcatttg attctttcgt
    24301 cattgccgct agcagactga cttttccttc ttgttcgttt gctaaaacaa gaatatctga
    24361 aatatttttt tgtttccatt ggtcagctaa ttgacgcagc tgattcatat ctttcacttt
    24421 tacttgtgct gcaatgattg tttttccatt gatcgtttct ggatctttga atacatcacc
    24481 agcttgttga ttcgctaact tgctagctaa ttgttcattt tccttttgta gctctcttac
    24541 ttgctgttgc aattgttccg cttttgaaac aacttctttc aattgaggtg atttaacaat
    24601 tgttgctact tgttttagtt gtttttcttc ttcttcaagt agttcgtacg cttctttact
    24661 tgttacagcc tcgattcgtc gcacgcctgc accaattcct gattcagaaa cgattttgaa
    24721 gattccgatg ttttctgtat ttgctacatg tgtgcctccg cacagttcga ttgaccagcc
    24781 gccaatattt actactcgaa cgtcatgtcc gtatttttca ccaaacaaag ccattgcacc
    24841 catgtttttg gctgtatcga tatctgtttc aattgtttca actgggatag cttcccagat
    24901 tttttcgttg acgattcttt ccatttcagc taattcatct gaagtgattt gaccaaagtg
    24961 ggtaaagtcg aatcgtaaat gtccaggagc gactaaagaa ccagcttgat ttgcatgctc
    25021 gccaagtact tctttcaatg ccttgtgcag tagatgggtt gctgtatggt ttttgatgat
    25081 ccgattgcgc atcgattgat cgatcaatag atgataggtt tgtccttcac tcattggtgc
    25141 ttttacttct acggtgtgca taaattgacc attaggcgct ttttgaacat ctgtaacaac
    25201 tgctacgatt tcgcctactt cattcatgat ccatccttga tccgctactt gcccacccat
    25261 ttctgcatag aaaggtgttt gatcaaagat catttgagct tcaccttctg cgacttcatt
    25321 caaaagagac tcacctttaa cgatgaccaa taattgacta tctgattctt gttctgtgta
    25381 tccaatgaat ttactttcta ctttgatatc tgtcaataaa gcagattgta cccccattga
    25441 tttttcagta ctgcgggcag agcgagcacg ttcgcgttgt gcatccattt ctttttcaaa
    25501 accagcatga tcaactttca gtccttcatc ttctgccacc tcttccgtta attctaccgg
    25561 gaagccatat gtgtcgtata gtttgaagat gtcttttcct gctagagtcg tcccgttttc
    25621 gttttttact tcttggatca cttgatttaa gatttccaaa ccttcattga ttgtttcatt
    25681 gaaacgttct tcttctgtac ggataacttt ttcaataaat tctttttgtt gaagtacttc
    25741 aggataataa cttaccatga tttccccaac aacagggact aaacgatata agaatgcttg
    25801 ttcaatacct aattttttcc catgcatgac agcacgacga agcaaacggc gtaagacata
    25861 ccctctccct tcattcgatg gcaatgcacc gtcgccaata gcaaatgaaa gggcgcgaat
    25921 atgatctgcg attactttgt aagaaatatc tgttactggg ttttcaccat attttacttg
    25981 tttgcttagc ttttctacgg cgtggataat aggcataaac aagtctgtct caaagttcgt
    26041 tgacgcatct tgaacgattg agaccatgcg ttccaatccc atccccgtat caatgttttt
    26101 atgaggaagt ggttcaaatg tgttatcagg cttatggttg aattctgaaa atactaagtt
    26161 ccagatttct aaataacgtt cattttctcc tcctggatag ttttcaggat cgtcttctgc
    26221 taaatcgtta taagcttctc cacggtcata gaaaatttcc gtatccggac cacatgggcc
    26281 tgcaccgata tcccagaagt tgtcttctac atcaataatg tgatctagtg gcaggccaac
    26341 ttcttcatgc cagatgcgtt ttgcttctgt atcttttgga taaactgtta cataaagttt
    26401 ttctggatcg aatgccatcc attttggatc agtcaaaaat tcccatgccc agtggatggc
    26461 ttcatttttg aaatagtcac caatcgaaaa attacccagc atctcaaaca tcgtatggtg
    26521 ccgtgctgtt ttaccgacat tttcgatatc atttgttcga atagattttt gggcatttgt
    26581 gattcttgga ttttctggca caactgaacc atcaaaatat tttttcaatg ttgcaacacc
    26641 agagttgatc cacaataagg ttggatcgtt cacggggatc aaagacgcac taggttcaat
    26701 cgtatgtcct ttagattgga agaaatcaag aaacatttgt cgaacttgtg cactacttaa
    26761 ttgtttcatg tcattacctg ctttctataa attaaataca aaaaaacacc atcacagcca
    26821 aggacgaaaa ctcgcggtac caccttgatt gcaatgatgt gtaatcatta cctcttaaac
    26881 tcgataacgc tgagctgcgt cggtatttct accaaaatag aaaaagggag caatttgatt
    26941 agtgactatt cttttttcag ccaagaaaga attttctgtg agtcttaaaa aacaaatcat
    27001 atccttttcg tacttaatta gtatacgcat tctattgatc actgtcaata tctcaatttt
    27061 tattttcatt tccttttggt catactccac gatttttggt acgataagaa taaaggaatc
    27121 aatacatctc tgctattcat gacaaggagg aatatgatga aaaaaatagt tggagcggat
    27181 gaatggatac gcgcagctag ctgctttttg agatatcaag tttttgtatt agaacaaggg
    27241 attcctgcag aactagaatt cgacggaaaa gatatcccgc aacaaaccta ttatctattt
    27301 cttgatcaaa aaagaccagt agctactttg cgttatgaaa agaaaacacc tacttgcttc
    27361 aagccggaac gattttgcgt agcaaaagaa taccgaggaa aagggttagg cggtcagttg
    27421 cttgaagctg ctgaaaaacg ggcggtttca gaaggttgtc agactagtta tgtagtagct
    27481 gaaatgacgg ctgtagattt ttatgaaaaa caagggtatc atacttgcac agaacctttt
    27541 attgaagatg aagtactttg tatcggaatg aaaaaaagtc tagcttaaaa acaagagatt
    27601 gtgacacgcc ttttgtcaca acctcttgtt ttttatttat gtgaattttt cttattttta
    27661 cgagcagtac ggctttgctg tctgcgttcg attttgcgtt cttttttatt tttttctgca
    27721 attgcccaat cgattttttt cttataacca ggcttgatct ttttcttttt cttcttcaca
    27781 agaccaatca gcgtgggatc taatacatct tttgattttt ctcgtttggc acgtctatta
    27841 cgatcgtatg ttttgacgat ttccccgttt ttgatttctt ttggttcaaa tgagacgccc
    27901 aatttttcta tcgcatcaat ggcttgctca tcatttggcg aatataacgt aatggccgtt
    27961 ccttttaagc cattacgtcc agtacgtccg acacgatgga taaagaagtc tagatcttct
    28021 ggaatttctg cattaataac atgagagaca ccttcgatat cgatccctct agcagctaaa
    28081 tcagtcgcta caacatattg atactccaga ttctgtactt gtcgcatcac tcgttttctc
    28141 tctcttgggg tgatgtctcc atgaatcttt gctactttca agccttggtt tttcaagtaa
    28201 tcggcaattt catccacatg ctgttttgta ttggcaaata cgattgctaa ataaggatga
    28261 ccaattgtca gcagttgata aatcatttga ttctcatctt taccttttgt tgaaatcagc
    28321 caattttcaa tgtcttcaga aataactgct tttggtttga tttcttcaat gattggattt
    28381 tccatgtatt ttcgtaagaa tggacgaagt ttttctggaa tagtggcaga aaaaactaaa
    28441 aactgcagct tttctggtaa tcgacttgca atttggtcta cttcatttaa aaaacccata
    28501 tccaatgtca tatccgcttc atcgacaaca aatgcaaatg cggtgtgaat cttcagcgct
    28561 tgttcattca tcatgtctaa tattctacca ggcgtgccta ctacaacctg tggctgttgg
    28621 tgatgcagac gatttaattg acgctgtttg tctgtaccgc cgacaaaatt cgagacacgg
    28681 atctccggtg tagaaaattt agcgatttgt gtagctgctt catagatctg tgcagctagt
    28741 tccctacttg gagctgtaat aacaacttgt acttcctctt tttctgcatt gattttttca
    28801 aacaaaggca acaaaaacgt atgtgttttt cctgtaccag tttgagattg cccaatgata
    28861 ttttttcctt ttgcaattaa aggaatcaaa cgttcctgga cctctgtggg ctgtttgaag
    28921 ccctttgcgg ttaacgcttc attgataaac ggtttgaagc ggaatatatc aaaattattc
    28981 attcgtgcac ctcttctctt taaattatca cgactttggc attataacac agacaaagcg
    29041 tttttgctca gctaatttcg agaatcatca tcctttgttt ggccaatcgt gctaacagta
    29101 tatgtgtgac tagctttttc ataaaacaga atccgttttt ttctcaaaaa tgatagcaag
    29161 atatttaaaa taaaaatacc ttgtagtaac aagacaccga gagaaatgaa tactgcactc
    29221 atctgcaaca ccgtattcgt tgtcgaattc atgatttgct gaagcaactg ccccaaccag
    29281 cttaaaccat aaaaaagaaa gtacagatac ccgtagcgga tcatcaatgc ttttaaagaa
    29341 attcgttcgc ggtcttcttc caccaaacgg atacgcacaa tttttttgcc aagtgtccat
    29401 ccattggtta taaacggtac aatcataaag tataccccta cttctaataa aagccaccag
    29461 atatgagaag taactgcccc tgaatcgaac gcaattttaa agaaaatcgc cgctaccaaa
    29521 ttaataagag ataaaaatgt ccagtcgatc aaataagcga ccaagcgtcg agtcaatgag
    29581 acagtctttc ctttttcata agaaagttca tccattcgtc ttcttgtagg aagcataaat
    29641 gtaaataacg gcgtaacgac aaaaccaatg attccaccca atgtatttgt cactaaatca
    29701 ttcacatcaa ataagcggta tggtcttggg tagataaaat aaagtccact tagctgcgtc
    29761 aattcaaaaa atagagaaag gcagaaacta gcaatcatcg ttttcataaa agaaagccgg
    29821 aaataatatc ttaaataaat gccaaacggt atgagtaata aaacattaaa agctggttcc
    29881 aaaaatacac tctgcttcat tgccggcagg taggtactag gttcagacaa gaccaatacc
    29941 gtgttgtctc tgaaatgttg ccatgaagca aataaatgca gctccatctt tggccctgtc
    30001 atttgggcaa ccgtctcctt tgccggaagt ggtaagatca ccaaaaaata cgcacacaat
    30061 aaataaaaaa cgaaagaata caaaataact gcccttgtta ctagaaatgt tccatacttt
    30121 cgatattcat aaataaaaaa aacagatgag atcgctaagg ctaaaaatgg aaaaacaatc
    30181 agcgcaaaac gaatcggttc gatataactt gccatatgac tcctccttga ttctttgtat
    30241 ctctcttatc ttagcagtcc tttgctgttt caagcaagta acgaggctat tatttctcat
    30301 ttctttcaaa gtaaagtaag ataaacacaa agggggtgtc gagatgctga atatgtactt
    30361 tgtttttggc gtacctattt ttttactgtt cctttatgct acgatcgctt atgtaagaaa
    30421 aagaactaca attcattatt taggatttat tctcctgatt atttcgggtt tcatgctagt
    30481 cttcaatctt cagacttggc agcaagcact tcttgaaatg gataaaatga ctccacatgc
    30541 tttgtctaaa gtgcttggct accctgtcta tctgatttgg cttcccattt tcatttctgg
    30601 ttgcttggtt ttattaaata tttatcgcgg cgtacgccga atagttcagt tacgcaaatc
    30661 aaagtaaaag acagaaatcg gttgagcccg atttctgtct tttactttgc tatttcatcg
    30721 tagacaaaac gacatttacg tgatcaaaat taacgagtac ttttgacatt tcttccacgt
    30781 actcctcatt taaataaaat attttgtttg gcagagaagt gcagttctaa taaaattcga
    30841 atgttttagc tatctacgtt ttaaatagag ataaatcggg ataccagcaa gtgtcaatac
    30901 tatccccatc gaagctaaaa aggtctgagt gataagcgtg cttgatacga taaaagtccc
    30961 tccaatgatt gctactagtg gaataaacgg atacattgga actttgtatg gtcgaaacaa
    31021 atcaggttct tttttacgaa gaagaatgac accaacaaag accatcgtat aaaaaatcca
    31081 aatgacaaag atcagcatat ccgttagtgt atcaaaacca ccgatcatca tcatgccaat
    31141 agcgatgact agctctaaga tacctgcggc tacaggaact ttagttttat catgaagttt
    31201 agcaaagagc ttgctaaaag gcaggttgtt ttcttttgcc ataacataag ggagacgcat
    31261 tccagtaagg gtatagccat tgatggttcc ataaacagaa atcaagatac caactgtgac
    31321 cagtcttcca ccgaagccgc caaaaatcat ttttgcaacg tcacttgccg cattgctgtt
    31381 tcctgcgact ccgtcgatag atgcggttct taagaacacc gcatttacta ataaataaac
    31441 gatcatgatt ccgatgattc ctaaagaaat tgcttttggc aaatctttcg ccggcttttt
    31501 caattctccc gaaatatttc ctacgtgtat ccaaccgtcg tatgcgaaca tcgttgctag
    31561 caagcccgct cccaaggctg agaaaaatga aagattttct cctgcttgga tcggaaacag
    31621 ttggaagtct actccttctt gtcggaacaa accgaaaatg acgatcacaa acaaaggaat
    31681 aagcttgcag acaagcgtaa tcgactgaaa agcccctcca gctttagaac ctaaaaaatt
    31741 gatcaacagg atcgatacag cagctgtaac agctacggga acaatcattg actgggaaag
    31801 accaaataga ttgacgaact gtgtaccgaa aatgatcgac aaggctgcta catttgctgg
    31861 aaaataaatc acgacttgcg cccagcccaa taaaaaagct gctgtatttc cgtaaatccg
    31921 ttcgatatat ttaatcatcc ctcctgtttc tggaatagca gctgccagtt cagctcctgt
    31981 tagtcctgca cagacagaaa tcataccacc gagaaaccaa gaaaacatat gcaaactggc
    32041 ggatcctgta acttctgcta cgcttgcggc tttaaaaaat acccctgcac cgatcactgt
    32101 gcccataaca gtcgataaag cagtaaaaaa tcccatcgta cgttttaatt cattttctat
    32161 ttttacttct tttactggcg tggcttgata ttcttccatc ccttgtcccc tttcatacca
    32221 tagccaatcc caaaagtata aaaaactttt tggatgtggt tcttgtttta taccgtctct
    32281 accaattttt ctttcagttt ttccaacata tcctttgtca tcacatctaa gtcgtatttc
    32341 ggcgaaaagc cccattcctc ttgcgcacaa gaaacatcta gtgaatttgg ccaagattct
    32401 gctattgact gacgtacagg atccacatca taatccattt caaaatctgg tatgattttt
    32461 tgaatagatg ctttgatctc ttccgggtca aaagacatcg ccgatatatt gaaggcattt
    32521 cgatgaacca atcgatcagg atctgcattc atgagtttta taatggcatc gatcgcatct
    32581 ggcatataca tcatatccat tgatgtacct tgatcaatga aactagtgta ctttccttct
    32641 ttgattgctg aataataaat atcgactgcg tagtctgtcg taccgcctcc tggcaaggtt
    32701 gcataagaaa tcaatccagg gaaacggaca ccacgagtat ctacgccata tttcacataa
    32761 taataatcac atagtagttc tccagctacc ttcgttaccc catacatggt tgtaggacgc
    32821 tgaagagtat cttgtggggt atgatctttt ggagtatttg gaccaaacgc gccgattgaa
    32881 cttggcgtaa aaaatttcag ctggaattct ctagcgactt ccaatgcatt gaccagccca
    32941 gtcacgttca aattccaggc taattgtggt tttgcttctg caacagctga caaaagagca
    33001 gccaaatgaa tcaatgtgtc cacttgatat tgttctgcta tgctgcgcat tttttcgtaa
    33061 tccattacat ctaggatctc aaagatatcg tttttctcaa tgacttcagg catgcgtata
    33121 tctgtcgcaa tgacattttc actgcctagt tcttgacgta gccgtgtgat caactctgaa
    33181 ccaatttgtc ctaaacatcc tgtcaccaat acttttttca tgatgatcct ccctgatctt
    33241 ttttactact atcttcagat gattaacaat atatgcgtga acatgttctc taattttaaa
    33301 tagacgaaaa aactaaattt agttaaataa tttccatttc ttttcctatt ttttgataaa
    33361 ctgctactgc ttcatcaagc atttccctcg tatgttccgc agtcggcata tttctgatcc
    33421 tgcctgtccc aagaggcaca gttggataaa cgattggttt agcataaatc ccatgttcga
    33481 tcagcttctt agagaaagtc tgagtcactt tttcgtctcc caaaatgact ggagtaatag
    33541 gtgtttcaga cataccgatg ttatagccta cttttttcaa ttcttcttta aaataattag
    33601 cattttccca aactttttcg acaagttccg gatgttcttg catcaaagta atcgaagcca
    33661 atgcagctgc agctgcacct ggagttagcg aagtagaaaa taggaatggc cgacttctag
    33721 ctttcaacca gtcgattagt gttttcgatc cagctacata acccccaaca acacctatag
    33781 ctttcgataa cgtgcccatt tgcatatcga ttttgtcgct taatccaaaa tgcttgacgg
    33841 ttcctgcacc ttttccagtt acgcctgagc cgtgcgcatc atcgacgtag gtgatcagtc
    33901 catatttttc aacaatcgga ataatttccg gcaatcgtgc aatgtctcca tccatggaga
    33961 aaacaccatc tgtgatatac atgatttttt tatatttctt actttctatc gcttcctttg
    34021 cttttttctc aaggtctttc atatcttgat gtttaattcg gatgattttt gctccggata
    34081 agcggcaacc gtcaataata gatgcatggt ttaattcatc cgataagata gcatcttctt
    34141 ttgtcattac tgcagagata gcgcccatat tgcagttgaa tccagattga aaggcgattg
    34201 ctgcttctgt ccctttgaat tctgcgattt tttcttctaa ttgctgatgg attttcagcg
    34261 aaccattgat cgttcggact gctcctgctc ctacaccata agtttcggtt gcttcaatac
    34321 atgctttttt caattcttcg cgattggcaa atccaagata attgttggat gctagattga
    34381 tcatcttttt tccgtctacg atgatacaag caccattttc actttctagt atgtcgatcg
    34441 tattgtataa ccccttttct ttcagttgat ccaattcttt ctctaaatac attgttagtt
    34501 ctttggaaga cattgtctcc acctccatat tcatctgtct tgcagaacat accaaacata
    34561 tatcgtgtca ttcatctaca aagcaagtat gctatatttt tgataacgct tacactgatt
    34621 atgagaatta tttaaccaca ttttttattt acagtatctt tttactttca aatgacttat
    34681 atagtatgaa caattacctt ttagataatg atctatttta ctctacctgg gcagataaat
    34741 acaacacaac cattgataga agccctttcg ttaaaatcaa ttgtattctg aatatttaat
    34801 ttatttattg catagaccaa taaaaataca taaaatttcc atcttcgttt atcagcaatt
    34861 tttaatttta ctctctgaat atttcttaaa agttttactt gttgaattcg aaaaaaggac
    34921 tgtgacaaaa gtcttgtcac agtcctattc ttccgaata
//
LOCUS       DAIGWC010000022        34899 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.022, whole genome shotgun sequence.
ACCESSION   DAIGWC010000022 DAIGWC010000000
VERSION     DAIGWC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34899
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.022"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(56..1285)
                     /gene="rpsA"
                     /locus_tag="NOB74_001099"
     CDS             complement(56..1285)
                     /gene="rpsA"
                     /locus_tag="NOB74_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HCI1220300.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(1420..2100)
                     /locus_tag="NOB74_001100"
     CDS             complement(1420..2100)
                     /locus_tag="NOB74_001100"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HCI1220301.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(2149..2784)
                     /locus_tag="NOB74_001101"
     CDS             complement(2149..2784)
                     /locus_tag="NOB74_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI1220302.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(2850..4253)
                     /locus_tag="NOB74_001102"
     CDS             complement(2850..4253)
                     /locus_tag="NOB74_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HCI1220303.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(4240..5271)
                     /locus_tag="NOB74_001103"
     CDS             complement(4240..5271)
                     /locus_tag="NOB74_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220304.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            5302..5523
                     /locus_tag="NOB74_001104"
     CDS             5302..5523
                     /locus_tag="NOB74_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HCI1220305.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(5688..6425)
                     /locus_tag="NOB74_001105"
     CDS             complement(5688..6425)
                     /locus_tag="NOB74_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HCI1220306.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(6578..7918)
                     /locus_tag="NOB74_001106"
     CDS             complement(6578..7918)
                     /locus_tag="NOB74_001106"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HCI1220307.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(8155..9678)
                     /locus_tag="NOB74_001107"
     CDS             complement(8155..9678)
                     /locus_tag="NOB74_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HCI1220308.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(10056..10667)
                     /locus_tag="NOB74_001108"
     CDS             complement(10056..10667)
                     /locus_tag="NOB74_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI1220309.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(10790..10915)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(10997..11713)
                     /locus_tag="NOB74_001109"
     CDS             complement(10997..11713)
                     /locus_tag="NOB74_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCI1220310.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(11719..12288)
                     /gene="scpB"
                     /locus_tag="NOB74_001110"
     CDS             complement(11719..12288)
                     /gene="scpB"
                     /locus_tag="NOB74_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HCI1220311.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(12272..13069)
                     /locus_tag="NOB74_001111"
     CDS             complement(12272..13069)
                     /locus_tag="NOB74_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HCI1220312.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(13039..13410)
                     /locus_tag="NOB74_001112"
     CDS             complement(13039..13410)
                     /locus_tag="NOB74_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCI1220313.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(13429..14316)
                     /gene="xerD"
                     /locus_tag="NOB74_001113"
     CDS             complement(13429..14316)
                     /gene="xerD"
                     /locus_tag="NOB74_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HCI1220314.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(14412..14885)
                     /locus_tag="NOB74_001114"
     CDS             complement(14412..14885)
                     /locus_tag="NOB74_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI1220315.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(14990..15853)
                     /locus_tag="NOB74_001115"
     CDS             complement(14990..15853)
                     /locus_tag="NOB74_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCI1220316.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(16049..18148)
                     /locus_tag="NOB74_001116"
     CDS             complement(16049..18148)
                     /locus_tag="NOB74_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCI1220317.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(18368..19477)
                     /gene="rpoD"
                     /locus_tag="NOB74_001117"
     CDS             complement(18368..19477)
                     /gene="rpoD"
                     /locus_tag="NOB74_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HCI1220318.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(19501..21342)
                     /locus_tag="NOB74_001118"
     CDS             complement(19501..21342)
                     /locus_tag="NOB74_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HCI1220319.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(21524..23839)
                     /locus_tag="NOB74_001119"
     CDS             complement(21524..23839)
                     /locus_tag="NOB74_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI1220320.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(24024..24884)
                     /locus_tag="NOB74_001120"
     CDS             complement(24024..24884)
                     /locus_tag="NOB74_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HCI1220321.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(24943..25464)
                     /locus_tag="NOB74_001121"
     CDS             complement(24943..25464)
                     /locus_tag="NOB74_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HCI1220322.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            25742..26503
                     /locus_tag="NOB74_001122"
     CDS             25742..26503
                     /locus_tag="NOB74_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1220323.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            26529..29120
                     /gene="mprF"
                     /locus_tag="NOB74_001123"
     CDS             26529..29120
                     /gene="mprF"
                     /locus_tag="NOB74_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCI1220324.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(29308..30495)
                     /gene="tuf"
                     /locus_tag="NOB74_001124"
     CDS             complement(29308..30495)
                     /gene="tuf"
                     /locus_tag="NOB74_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCI1220325.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            30863..31219
                     /locus_tag="NOB74_001125"
     CDS             30863..31219
                     /locus_tag="NOB74_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI1220326.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(31460..32464)
                     /locus_tag="NOB74_001126"
     CDS             complement(31460..32464)
                     /locus_tag="NOB74_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HCI1220327.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            32630..33481
                     /locus_tag="NOB74_001127"
     CDS             32630..33481
                     /locus_tag="NOB74_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI1220328.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            33498..33743
                     /locus_tag="NOB74_001128"
     CDS             33498..33743
                     /locus_tag="NOB74_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220329.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            33930..34634
                     /locus_tag="NOB74_001129"
     CDS             33930..34634
                     /locus_tag="NOB74_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220330.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         9844 a         7317 c         6027 g        11711 t
ORIGIN      
        1 agaaaaactg agacaaaagc agctgctttc atctcagtca cagatacaaa atcaattatt
       61 tttcagaatc atcggttgct ttttcttcta cttcttcttt caacgcatca cctaaaatgt
      121 ctcccatagt aaatccagta ttttcttctg gtaattcata agactcaaca ttttttggtt
      181 cttcttctga agctggtttt tcttctaaag ctttgatact caatgcaata cgatgttctt
      241 ctggatggat ctctaatact ttcactttca cttcgtcacc ttcatgaagc acttcatgtg
      301 gtgtcgcaat atgtttatgt gaaatttgag agatatggac tagcccttct actccaggga
      361 acacttcaac aaaggcaccg aagcttgtca aacgtttaac tgttccgtct aatactgtgc
      421 caactggagc ttttgtatcg atttctgacc aaggtccagg ctgtgtgtct ttgattgaca
      481 aggaaacacg ttcttgttca ggattgatag acaacacttt gacatttaca tcatcattga
      541 cagccaatac atcacttggt tttgctacat gactatgtga aatctctgag acatggacta
      601 gaccgtcaat tccgcctagg tcgacaaatg cgccaaaatc agtaagacgt gcaacacgtc
      661 cactgagaac atctccctca tggatagttg aaagaatttc ttttttcttt tcttctcttt
      721 cgttttccac taccgcttta tgcgataaga tcaaacgatt ttctgatggt tcgatttcga
      781 tgattttaaa gctcaatgtt ttgcctttat agtctgaaaa gtctgcaaca aaatgatctt
      841 ccaccattga tgcagggaca aaaccacgta caccgacgtc aacgactaaa ccgcctttga
      901 caacatttgt aacaggtgct tcgatgacct tgccctcttg gaaatctctt tcgatatctt
      961 cccaaacttt tttagcatct aaacggcgtt ttgaaagtag atagctgccg ttttctttat
     1021 ctttgccgat cgtactgata acgactaaat ctaatacatc accgactttt actacttcgc
     1081 tgatatcttc taccggcaaa gttgataatt cttttgccgg aacgactcct tcaactccag
     1141 ccccttcgat tccgacaatc acttgtttgt cttcaatgac taaaacttcg cccttaacaa
     1201 catcgccaac ttttacttct tgtacgcttt tcattgcgtc ttccattgac tggttgttct
     1261 cttgattttg atcaaattct gtcataacac ttgtcctcct aaccaacatt ctgccgtaag
     1321 tacggtactg tttttagttt aattgattat tcaaaaaaaa taaagcgatt tcgttcgttt
     1381 tccttgaaaa aacaattgtt tttcattttt tttcttaatt taaaaaagaa gataaccttt
     1441 tttcaaaaca acagctttta ttgctgcaac gacttctgga atcgatttgc cagtcgtatc
     1501 gatacgaaca gcatcctctg cttgcttcag cggagagacg tcccttgttg aatcataatg
     1561 gtctctttcc tgtatctctt tcgtcagtgt ttcaagatca gtcggaattc ctttttcttg
     1621 gttctctttg aaacgtcttt ctgcacgctc acttacgctt gctactaaaa agattttcac
     1681 ttctgcattc ggtaatacag ctgtcccgat gtctcttccg tccatgacaa cgccaccgcg
     1741 ttcccctatt tttcgttgga cagcaactaa ttcttctctg acttttccat gtgcagagac
     1801 ttcagaaaca gcttttgtga catctggttg acggatttct aaagtcacat cttttgatgc
     1861 tatgaataca tgctgtccat cttcttgttg cgaaaaagag ataggatact ttttgatcag
     1921 cgaaactagc ccttcttcat ctgaaaaaga tacattgttc gtaatagcta aataagttac
     1981 tgcgcgatac atggcaccgg tatctgtata aatataattc aattcttttg ctaatatctt
     2041 ggcaacggta cttttcccag atgaagcagg cccgtcgatt gcaatactga tttgtgtcat
     2101 gatataactc ctttttctca gaaaaaaagc cgcaaagcgc ggctattatt atttaattct
     2161 taattcttga ccagggtaaa gcataaagtt gtttggatct aagccattca attcaaacaa
     2221 ttgatcagtg gtgatccctg cacgctcagc cacttgtttt ggaccttcgc ctgcttgaac
     2281 agtcgttgtt gaaccggctg cagctgatga agaaggtgtt gtttctgctg cattgctgct
     2341 tgaatcccct gcttgataag ttgcctcact tgaggaagtc ggtgttgtct ctgctgcaat
     2401 actgctttct gacgttacac ctgtatcttg agacacagta gattcttccg cgattgtact
     2461 agattctact gttgaagtct cagttgactc ctcttttgtt gtacttgtag aactttctac
     2521 tactgatgtc gaagtttcag aagaagttgc tgctgttgca ttgttgcttg atccatttct
     2581 gatccagaaa taagcacctg ctggaatagc gatacataag accagtaaaa tcaaaaatag
     2641 cgaaagaaat aatgtatttc ctttcttttg ttgtctctga gaacttcttg atgaaacttc
     2701 atcatctgta tcgtagattg gttgttccca tggttcttgt gtttcgttat tttctgtaga
     2761 ttgatgtcta tcttttctgc tcactgtttt acctcctaaa ctctatcgtg tgtattatac
     2821 cataggaaaa agtgtcttgt cctaaaaaat caatgttcca tgtttttttt aaataaattt
     2881 agtaaaatcg ttccccaatg aagttgttca gtcttagaaa aaagcttcct ctttggcaga
     2941 agttctgctt ttgctccatc aatatcacaa caattctgcg gcttttcgga gagtttttcg
     3001 ccaaaataag ctaagatgaa ttttctgcgg cagttttctt cattaatata gcgaagcatc
     3061 tgctgcaggc ggaattcttt ttctttttcc tgacgtttga gccgttccac ccaattttct
     3121 ggtttttcag actgctggat cagctccatc catttttttt gcagctcatc aaagggagct
     3181 tgctctgtgg catattccaa ataaagctca aaactttgtc gctgttctct agaaagttga
     3241 ttaaagaaat aatggatacg ttcatcccca ctttgataaa aaagaattgc tgcactttct
     3301 tcctgatctc tgcctgctcg accgatttct tgtacatagt tttctagact gtctggcaaa
     3361 tcataatgga ccacataacg gatatcagat ttatcgatcc ccataccaaa tgcattcgta
     3421 gcaatgagaa actgcagctg attttttaca aactgctgtt gaagttgtct tctttgagct
     3481 gcatcaagac caccgtgata gtatccaact gtaaaacgtt ccctgaataa atgatacaat
     3541 cgttcgactt ctttttttgt tgcacaataa atgattgccg ctccttgtgc tctttccatg
     3601 aagtgttcaa gttcttgttc tttttgctgc gttttccgaa caaaaagcga gatattttgc
     3661 cgattgactg attgtctgat ctcttttggt ggtcgatcaa atagtacatg acgtatatct
     3721 cttgctacta aatctgttgc tgtcgccgtt agtgccagtg tgaccgggtt tcctaaaagc
     3781 tttcggattt ttcctaactg ttgatattct ggacggaaat caactcccca ttgagacacg
     3841 caatgagcct catctactac atataacgca atattttgtt ttttcagatg ctctaaaaga
     3901 gaaggattag tcaacatttc gggactcaaa aacaaaaatt tatattgcga tagatgacgg
     3961 aggacgtatc ttctttcaga ttgcgaaagt aaactattga aagcagctac tcgtttctcc
     4021 cctcgttttt gtaattgcgt cacttgatct tccattagag aaagcagcgg tgacacgatg
     4081 atgaccagac cttccattaa ataccccgtc aattgatagc aaaggctttt tcccgttcct
     4141 gtaggcaaaa tagcgagagt atcttctcca tcaagcaacg cctgaataat ttcttcttgg
     4201 ccgggacgaa atgaatcaaa tccaaaatat ttttttaatt catttattaa cattctgtat
     4261 cgcttccttt ctcaatagat agatttgata caaacgaaat tctccataat ctaattgtcc
     4321 atctacattc cattcgctaa agcgccactc tcgcacggaa tccttatttg gttccaaacg
     4381 ttcgattgtt tctgcagaga gaatccactc gtatggaaaa tcatcaaaaa acaaggccca
     4441 ctcaataaga tgatctgtta ctgttcctct ttttaaatga cggattgcca tgatctggtc
     4501 aattgtctga ccattcataa acatctgctt ggtgatcatc atgctttgat tgaaattttg
     4561 ctgtaataat gaatcgatca aagcgtgcca aagcgaatct ggccgttttt cgatttgtgc
     4621 taacaaaagg tggatacatc tgctttgttg cagataaacc gctgactcat cattgttttt
     4681 tgccagctga taaggaagca gccctgttcg ctcatttcca gataattggt tagctaaaaa
     4741 atctgctgct tcttctggta tctccgaaaa cagctgcacc aaactctcat acgcagtatc
     4801 aatcaaaatt tcacgtggca attggctttc actaagccat ttttttagtt ggaaagtata
     4861 aaaaggactt gtctctgctg gaagatagtc ttgaataccc gttgccagat tagaaattac
     4921 ttgaacagca aatttaatga gccgccaact agtttcccct gttctgccat agcggtcaaa
     4981 acgcaaacca gtatgttcta tttgatgttc ggacaacata tcagcccctg caggcgttag
     5041 ctttgcttca ttttcattta tttcgatcca accttgctgc gcaatttttt gcaaaatttg
     5101 ataaaactta tcctgcttca attctggaaa actgttatgg ataaacaaaa gttcgtgggt
     5161 aaatccataa ataagtactg aagtcgttcg ttttcccaca aggagttggt aaagagaact
     5221 aatccgcagc ttgtgtcctg atgaaaatag cgataaaata aaaacaatca tattattctc
     5281 cttaagttag gatggttaga aatgtcacta ctatgtaaac ttgtacctga acgctgtatt
     5341 gcatgcggtc tttgtcaaat cgaagcgcca gatattttcg attatgatga agaaggaatc
     5401 gttttatttg cccaagaacc agaggctcat caacagttcg tgatgccgga agaagaaaca
     5461 tatgtaaaaa aagcgtatca aaaatgtcca gttcgagcga ttttattaga aaataaaata
     5521 taaatataaa cgaaacttta aaaacgtaca ctaagttctc taaacttgaa aataagccgg
     5581 gatctgtttc tcttgttccg tgaaatcccg acttattttg aaagattcat ttgctatcta
     5641 tagttaattg actagttttt tcacggaccc tataggaccc atttatatta tttcaacttt
     5701 ttcagccagt tttccaatgt attgacgatc acagtttgct ggtctgcgtt agaaatttct
     5761 gcctctccat ctcctttttg ctcaccatag ctgccaaaac ctccatgatt tccgccattg
     5821 attgatacat actctgttct ttccggtaaa tactgcttag cttcttgata agcttcctga
     5881 ttcaatactt tatcttttgt cgccgtgatc gataaaacag gaacagctga ttctgtcaat
     5941 gttccttttt tgtcgggata acttgccatg aagaataccc cttttaaatg tttgtctgaa
     6001 tgattcttat tgacataacg acttgccatt acgccaccta atgaatggcc accgatcaca
     6061 taatcggaat ttggaaaatc ttctttgacc ttatccgctt tgtttccgcc catcactgct
     6121 agatcaagtg gcattttgac aatagcgact gaaaagccgt tttttgctaa atcttgcgcc
     6181 caaatactat aactttctgg ctctacgaga gcaccaggat aaaaaataag taatggagac
     6241 tttccatgat tctttttctc tccttcaaaa aataagtaat cttctttgtt ttttccttct
     6301 tttaccaaca cttgcgcttc tgacgatggt tcgtacgtat tttgctgtat atagtaataa
     6361 ccggctccac cgagtaatcc taaaatgatg actaagccaa ttagtattcg tctaaatatt
     6421 ttcactttct cccacctttt ctatctgagt gacccctttt tcttaatcaa gtatgattat
     6481 accttaaaaa aataagagag aaatgcaaac tttccagcat caaataaaaa aagacggaat
     6541 atccatttga atatccgccc tttttgtatg tttattttta tttagcacat aaacgataca
     6601 cagcttctgc ataaatttcc attgctttat acatactact taattcccat cgttcattcg
     6661 cctggtgcat aaagtcagga gtatcaggga acatcgcacc gaatgccaca cactggttca
     6721 tcgtacgagc aaaagtagcg ccgcctgata caaacggttc agtcatgtct ccagtaatat
     6781 cgcgatatgt ccccaataga tttttcacta actcactgtc tagtggcacg tataatgaat
     6841 caaggaagtc aaattcttca taagtcaacc catatttttc tgctgtttta gttaatttag
     6901 ctactaaatc atctttcttg aatgtaacag ggattctcat atctacaccg atttttgttt
     6961 gttctggtgt gatttccaaa cttgcaaagt tcatcgttag ctcgccggat tgttcatctt
     7021 ctgttttgcc cacgacagct tcaccagttg cattttcttg aactaatttt cctaagaaat
     7081 tgattgggcc aaaatcaaat acttctgaaa gagcaattgc cagacgagaa atagcattca
     7141 ctccttgtgc tgcatctttc gcgtggatac ttttaccaag aacgacgatg ccttcacctt
     7201 gttcttcgaa atcgaattcg tgttttttca atgcttcttt tacttcagaa agcttttctc
     7261 cagagtaagg agctgcatca ggaacaacat tcaacgctcc tccagctttt acagaaaact
     7321 cgttcgttcc tggtcctgtc aagtaagctt gcaataagcc tttttctgca taaattaaag
     7381 gaaattcagc atctggcgca aatccttgcg taattccttc ttctttttcg ttatattttt
     7441 ctaaacaacg ccataaattt tcttcatctg taccaaagat aaaacgaata cgtgtcttga
     7501 attccacgcc agcatcaatc aaagctttga cggcatacat tgccgcaata gaaggacctt
     7561 tgtcatcttg ggatccgcga ccaactaacc agccgtcttt tatagttgga tcgaatggtt
     7621 ttgtttccca attattttcg tcccctgctg gaacaacgtc catatgacac aagataccga
     7681 ataattcatc tccagagcca atctctgaat aaccgtaata gccttctgga tctttaaatg
     7741 ttctaaatcc tagcttttca ctgatttcca atactttatc caaagcttca atcacttttt
     7801 taccgaaggg atgtccttgt cctgaatctg cttcatctag tacggaagga attcggatca
     7861 attcgctcaa tgattctaat gcttgttcat gatgttgttc tgtcacaaat tttttcatga
     7921 tattatcctc ctaatatgtt aaaaagggtc atgtcaaatt cctccgacac aacctcttct
     7981 tctcaaataa tgacgtttta agcctgctcc atcagcaagc agaatgttct taacaaatga
     8041 tgaaagaaaa aacactcact gaatggagct attgacttat ccacgtgctt atcgatagcc
     8101 gtttatcggt ttcttcattc ttatgataga ccttgtacct gtatttgtct aggtttagaa
     8161 cattgctgct acacctagga tcacacagat ggctacaaat aatatcgcaa ttaatttacc
     8221 ggtaaatttc caccacactg aaacatcgaa acgagcaatt gctacagcac ccattacgat
     8281 agcagatgtt ggtgtaatta agtttactaa accagatgca gattgataag cagtgattac
     8341 taaatcctta ccgacgccgg caaattcacc cataggtccc atgattccca ttgttgcagc
     8401 agctaagccg gaagttgaag gaatcaagaa tgacataggg atatagaaaa taaatgtaat
     8461 aatgatgaat acacttgaag ataatgaact taatccttgt tcgccccaat gtaagatggt
     8521 gtctgtgatt aatccattgt tcataaccac ttggatacca cgagcaacag ctactacgat
     8581 tgctacaccg atcaaatcag aagcaccagc taaaaattca gagacaaatt cagactcttt
     8641 catgccataa gtgattgcta ctacgatgga cattactaag aataacatag taatttctgg
     8701 gaagtaccag tcacctaatg gaagcatgct tttacctaga accgtaccta gtaccggaag
     8761 gtttgttaac cagtttgtca atgattcaaa aatcgtgaaa ttcgcattca aggttgtcca
     8821 aggaatcaaa ctgatgatca tgataccaaa agtaataaag aacaatacat taacatgttt
     8881 ttgttttttc gtgattactt cttgacgacc gattgcttca atatcgaaat gcttcatatc
     8941 ttctttacgt tggttgtata ctaatgattt tgttggatct ttttcgatct ttgatgcata
     9001 acgatacaca tatacaatag aaatagctaa caaaataacg aacatcaaga atcgaagacc
     9061 aataccttca cccatcgaaa tcccaacagc ttgtgaagct acgcctgttg caaaaggatt
     9121 taccgttgaa gctagacagc ctacttgaga ccctactaat acgattgcta cagctactac
     9181 tgtatcaaag cctacagcca tcatgactgg gatcagtaaa gcatagaatg gaatcgtttc
     9241 ttctgccatt ccgtaagtag agccgcctaa tgcaaataac agcatcaata ctggaataag
     9301 cattttttct tttcctttga atttcttcac aactgaagca atcccggcat ctagtgcccc
     9361 tgttttgttg ataataccta aaaatccacc aacaaccaaa atgaagaaag agattgggat
     9421 tgcagcaggt gtttctttag ttagctcccc cgctggtaca cctagcatcc cattgattgg
     9481 cgccatgaaa atatcccaca gcccttgagg attttgttgt actcgttcat atgatccagc
     9541 gacgatgttg cctgcatcgt ctacactata gtgcccagct ggtataaacc aagtaagtac
     9601 agcgattact gcaataataa taaataagac cgtatacgct gaaggcattt gaaatttttt
     9661 cttttttgtt tgttccatct tcttcttcct ttcttttccg ttagagacaa caattttggc
     9721 tctaatgtta ttttatcaaa aagagtatca gaacaaaaat aataacacgc attttgtaaa
     9781 acttttgttc aaaaagttcg tttttcccta ttccctcctc ttttttcagg tttttaaagc
     9841 tttcttcttt ttcattgtag cgtttccttt tttttataaa caaacatttt cgtcttttaa
     9901 aaggagaaga atttcacatt tgcaaagaat tgattgattt ttatgcataa atcaaaaaaa
     9961 tactcaaaac aaacaaataa aacgtttaca ttattgcatg tcttgtattt ttttccaaaa
    10021 aaaaagacca agaaatttct tgatcttttt gatatttatt tgactgctgt atgacgttgt
    10081 tcgaactgat gttgttttcg acttaaccat ggaagaagtt gcgcatgcag cactaaaaag
    10141 acagcactca cgatgaatcc tttgatcaag ttgaaaggaa cgatcccaat cagtacatag
    10201 tttgctaaag acatgcccag catctgtgtt gcgttcagcc ctaaaaacat taagtaaaga
    10261 ggcgtaataa cgaaataatt tgcgatactc ataaaaatag ttagagcgat ggttcctgta
    10321 atgacaccta aaaatttgtt tcttccttta tgctgtttct ttacactaaa gaaataataa
    10381 atcgggaatg taaagatcgt tgttgataag aaactagcag tgtctcctac caaattatcc
    10441 ggagaaaaac ctgtagtcag cagatgtaat actgaacgca agaacgctgt tgcaactccg
    10501 gccgctggac cgaataagaa catgctgatc aataccgaga tatcactaaa atcgatcttc
    10561 aaaaaactaa aagccggcat gatcggaaaa gcaaaatact gtaaaactaa tgcgatcgca
    10621 gcaaacatcg ctactgcaac cattttctgt acacgggtgt tcttcatttg aaatcctcct
    10681 gttaggactc ctcttcagcg aactttttga cgtttctctc caaatgaaaa aactctattt
    10741 tccagggaaa atagagttag agttatttga tcaagcgtcg tcaaataagc tctatcttct
    10801 ttatccagac tatactgtcg gtatcggaat ttcaccgatt cagctatttt tttgcaaaat
    10861 aggtcgtgga ctataaccac cggtcgggaa tttcaccctg cccctgaaga cgaaccttat
    10921 ataatttttg tttacatatt cattatacat atctattcaa aaaacgcaac atctaacact
    10981 tataaaaagt aagtgttcat tttgagtggt tcagcaaact gctgacttct tttttgttca
    11041 gttcacggta atccccagga cgtaggcctt gtaaagtcag atctccgtat ttttcacgtt
    11101 ttagtttttg cacaggaaga ccaactgctt gaagcatatt tttcacttga tgattacgtc
    11161 cttcgtggat cgtcaattcc acgatactgt ggtttgtctt aggatccact gataaaattt
    11221 ggaatttagc tggagatgtt tttcgtcctt cgatctttat tccttttgtc aaaggtgcaa
    11281 gcatcgattt tgtagcgatc ccttttacct ttgcaacgta aactttatcc acttcatgtt
    11341 ttggatgtgt caggcgctga gcaaaatctc catcatttgt cagtagcaag atccccgaag
    11401 tatcgtaatc cagtcgacct acaggataga tacgttcttt taccatcggc aaaagatccg
    11461 taacaacttt tcttcctttg tcatctgcaa cagcagaaat aactccttta ggtttgtaca
    11521 ataaatagta accgtattct tcttgataaa ttgggacttc atccacttcc acagtgtcat
    11581 gtttcccaac ttttatccct aattccctta caacttgtcc gtttactttt acacgtcctg
    11641 caaggatgaa ttcttctgct tttcgacgag aagtgatgcc agcgtgggca attactttct
    11701 gcaatctctc cattacaatt attctccttt attcattcca tcaaagaata gatctggtga
    11761 cacgtcttct tcaagtgaaa tttccatttc ttgtgtatca ggcagttctt ctaatgattt
    11821 caaaccaaaa taatctaaga agtagccagt tgttccatat aatatcggcc gacctggtcc
    11881 ttctactcta cctttttctt caatcagttt atgggcagct agacgctgta ccgctcctga
    11941 aacctgaact cctcgaatct gctcgatttc agctcttgtg attggctgtt tataagcgat
    12001 gattgctaag gtttcgacgg cggcttgaga taatgtgttt gatgtccctt gcgcatatcg
    12061 cttaagtaag ggagccagct cttttttagt cgttaataca taatggcttt ccgtttcaaa
    12121 aatatgcaaa gctgagtgcg agttttgagt gtaagattct tttaattctt tcactaaact
    12181 tgtgacttct gcttcgctga gatttaacag tccgcttaat tcttcattac tgatcccttc
    12241 ctcgccaaca ataaaaagaa gggcttcaag ttcacttaat ttcgtcatgt tcggtatctc
    12301 ctactgctgg ataaagcata attgattcat agttttcttt ttgttgcgca atgatctgcc
    12361 cttttttcat caattctagc aaagccataa aagtagtgac aacttcactt ttagaaggtg
    12421 actcaaaaaa agaatcgaaa gtacagccat gcgcatttct ttttatacgc tcttcgataa
    12481 ataccattcg ttcttcgatc gttgtgtcat cgggcgtgat cgttttttcc actttttgag
    12541 aaaatttctt acgttctaag attttctgca tggcacggat caaatcgatt tttttgactt
    12601 gtcctcgctt caacggcttt tcagcatccg ctaacccatc gatgttcata ggttcttttg
    12661 tgtaataaag acttcgttcc tctgcttttt ctgtcagtct ttcagctgca tatttatatt
    12721 tacggtattc taaaagctga gtgaccaatt cttctcgagg atcttcttcc cataattctt
    12781 catcgtctgt gacgaattct tggacaggaa gcaatgtctt gcttttgatt gccatcaatg
    12841 tagcagccat cactaagtat tctcctgcaa cagctagctc gagtgttttc attgtatgga
    12901 tataattcat atattgctcc gtgatcgtag cgatcggtat atcatatata tcgatttcca
    12961 tttgctgaat cagatgaagc agcagatcga gaggaccctc gaatacatct aatttaatat
    13021 tgatctccgt caactcattc actctttctt ctttttcttt gctagccatt ttccaatgta
    13081 aggctctgtg atttcagttg cacggatgga gacatccggg tacttttcct gtaattcatc
    13141 taacatttga aagcccatat tctcaccgcg ataagacgga ttcaaagaaa tgtcatggat
    13201 gatcagctga tcgttcgttg cccagtaaat accaataatc ccttgaatgt tggttgaacc
    13261 ttctggcgta aagaaaaaaa gttcataatc gtcttcagat tcgtacgtat caatctcctt
    13321 caacaaagaa gttttacctg tcagtttctt atggaaactc aatagtccca tagcaatttt
    13381 acggttttct ttccggtaat gtgttaacat cttctcacct tcctatgact aagcccttgg
    13441 aaaatgctgc ttataaacat ccgtcattct tttcttcgtg atatgtgtat aaatctgagt
    13501 cgtagagata tccgcgtgac ctaacaattc ctgtactgtc cgcaaatcag ctccattttc
    13561 tagcagatgt gtggcaaagc tatgccgcag cgtatgtggt gttacttctt tgtaaatccc
    13621 agcctctcgt actaactgct tcagattttt ccagattcct tgccgagaaa gacctttccc
    13681 atgattattg acaaatacat gcatttcaga tgcgtccttt acaagtaatg gacgtgcttc
    13741 gtctaagtag cgttccagcc attggatcgc ataatcacct aaaggaatga tccgctcttt
    13801 atctcctttt ccaactgtct gtaccagtcc aagagaaaga tgaagatctc ccaatttcaa
    13861 tccaatcaat tcactgacgc gcatcccagt agcatacatg acttccaaga ttgcacgatc
    13921 tcttatccct aacgtttttg tcgtatcagg tgcttcaatc agcttttcta cttctgtcag
    13981 agtcaatgta cttggtaatt tctgtgcttt cttcggcgta tcgatatgtt gcatcggatc
    14041 atgatcagtg atacgctctt gccgtaaaaa ctgatggaat cttctgagac ttgagatcat
    14101 ccgagtaaca gttgctgtcg cttttttttc ttcatgcaac ttctccagaa aacggatgac
    14161 taaaaagcga tcgacatcct gccatgaagc aattttctgc tcctgtagaa aatgcaagta
    14221 ctgttccaaa tcacgttcat agctttgtcg tgtattggcg gacaatcccc gttcaatatt
    14281 caagtagtgg agataatcgt tgatttgctc tttcataata atccccctca tgcctctcta
    14341 tcatatcaga taccgcttca ttctgatagt ctttttccat aatctgagca aagaaaaagc
    14401 cgtctagaca ctcagacgga ctggtttctt ttttcttttt catagcattc ctgacagatt
    14461 ccatggaacg ttagccgatg atcttttact aaaaaatgat aacgttcttc tactacttgc
    14521 tccacttcaa gtaaaagatc ctcttctact tcctcgatcg tgccgcagtt caagcatagt
    14581 aaatgatgat ggaaatgttt ggcgccttct tttctcaaat cataacgggc taatccatca
    14641 ttaaaactta ctttatcgac aattttcaat tctgtcaaga tttcaagggt tcgataaaca
    14701 gtagcaagtc caatttccgg actctttttt ttcactaaaa agaagatttc ttctgcagat
    14761 aaatgctctt tctcattttc caaaagcaca agcagagtag cttctctttg cggtgtcagc
    14821 ttaaaccccg cttcatgtag ctgctgtttt gtttttttca tcgccgaaat agcattcatg
    14881 accatttact caaccccaac aatttataat aattacaaat aaaaaaagat ataacactat
    14941 gttaattaaa attattataa gctagttaag aaaaacatgc aagggattct caattagatt
    15001 ttttgactag ttttgtcaca ccgttttctt gtgtaatcaa tccttgtttc aaaagattac
    15061 ctaatgcgcg cttaaatgct cctttgctga taccaaaagc tttcatgatt tcttctggat
    15121 ccgatttatc tgtaaagttg atttgctgat ctgcagaacg ttctaaaatg gttaaaatca
    15181 tttgtgcatc atctgatata gcttcatatg ctcttggctt caatgaaaga ttcagtacac
    15241 cgtctggtcg gacaccaatc actcgacctt ttatctgctc gcctagacga ggttcattat
    15301 atcgttcaga aggatggata aacccaagat agaaatcttc cgttaaaacg tacgtacctg
    15361 ttaatttcaa gcggtatgct gttcctatca catctttgtt tttcatttct tctgttccat
    15421 atttgcttaa agatttgaat attttttcat ctgctaaact gccccaaata cggtcttttg
    15481 catcaactct aagggaaatc atcaagcgat cccctttttt aggccatagc tctgtcattg
    15541 tcggcaattc atcaagagat acgacaaagt ctttatctgg aagaccgata tcgacaaacg
    15601 cacctaaatc ttttcgtgta gcagtaacga ttccaaaagc gtaatgaccg atacggcttt
    15661 taggaatttg tgtagtgatc cgattttcat gtttttgatt ttggtaaccg aatccttcaa
    15721 ctgcttcacc gattttgtgt tcaccttctg atttgcttaa gccaaaggtt tgtccgtttt
    15781 tttggacaaa gtagtttttt tcattttcat caataataat acctgtaaat atagttgcta
    15841 ataaatcgtt catttttttc tccctctata gtgaaaggtt ttcttaatac atttctttgc
    15901 tatcataaca taatgttatc tacttgaata gctgagcctt ggtttggaaa ggtgaaaaaa
    15961 ggagtatgac aacagttgtg tcatactccc ctttttcgaa taaacggtgt taaacggcag
    16021 gctcacagcc tctttcattt gcctaaaatt aattgctccc atttcctccg aaccatccag
    16081 ttttacagtt gatggttacg atgtaaaatg gcaaagcact ttctccaatg cctttcatca
    16141 atgcagattt tgttgaagtg gcatatagat tataatagcc ttccccattt tcgattctgg
    16201 ctttttctaa tctgtaacct ccttcaacga tatatccacg ttggatacat gtagcaatca
    16261 ctttgctttg gacacctggt gcccacgtcc atgctggatt agatgcatcg gcaatatcac
    16321 ttgctctggc agatttgatt ggctgattcg ctgagtttga agaggaaggg gtcgaggatg
    16381 ccgcttcttg ctgtgctgct tgtgcgaccg cagcttgttg agcggcttga gctgcagctg
    16441 ctgcttgagc ggcttgtttt gcttgttctt cagctgcttt tttcgcttct tctgcttttt
    16501 tcttttcctc ttcttctttt ttctctttat cagtgagcat cttatctact tgtttcaatt
    16561 gttcattcaa ctgagcagat agatctgtat ttttcacttt ttctactgct tcttttgccg
    16621 tcttgtattg gtcgcgtgtt gctgaatcca ctacttttcc gtctttaaag actatagctg
    16681 ttttttcttt agctgtttgc aattcagcat attgattttt agcttctgtt tgtgcttgtt
    16741 gaatcaattt tccaaaatct gtgttatccg tttcgattgc ttggatctct ttatctgctt
    16801 tcaacttgat gtcatctgct agatgatcat cgacgatggc aggtgctatg aaccactcat
    16861 tcactttttg gatatctcgg atcttagatt ggatatcttg gtaagttgtt tctaactctg
    16921 aatatccttt ttcattctta agactggata aatcattttt tagttttgat aaatcttgat
    16981 gaatcatatc tgcacgaata aattgatggt gatcatctgt ataaaaggca gcaagtttct
    17041 catgaagttc ttccatttgt tgctgtcttt ttgcttctgc tgctacttcg gcttctactt
    17101 tttgatgatg gtcataataa gcccagcttc ctccaccgag tagaagtact gctgctaaaa
    17161 cgagataagg tacttttttt gattttttct tttgcgcttt atctggatct gttttttcta
    17221 agtttgattc ttgatgtgtt ttttcagtat ctggcacgat tgttattgat ttcgcttctg
    17281 cttcaaacag cttaggctgg ttctcttctt tttctatttt tgcttcaaga tcagtaccct
    17341 ctttgcttac agattgattt tcagcatcgg attcactatt tatttcatcg ggctctgttg
    17401 actttttgtc tgtgttttcg agtatttctt ttttctctgc ttccggcagt ttattcgttt
    17461 tttccttttc taattgtttt tcagtaaata cttcagtttt ttctgtgata tccgttttta
    17521 cgtcttttat ttttactgtt tctttacctg tggcgttttc tctatcagag tctttttcag
    17581 tttcttgttc cttttctggc tctactttgt tttcctgtgc aattttttca ctgatcattt
    17641 tgagcagctc tttcgcgtgc tcttcttttg tatcttcacg atgtgctttg atataagcgg
    17701 atagtatcga attttcttcc tcattatcga cgatttcttt cagttcagct actcttcttt
    17761 tttgttttga ttcaagcgtt tcttcttgat tctttcctga ttcttccgaa gtctcatgaa
    17821 cagttgcttt cttctgttca tttttctcta tattagttac ttgatcgtga gcaggtggtt
    17881 cttcgtcttc tggttctgct ttttcgaata attccattac agattctaga ggtaaatctt
    17941 tcaattccga ccattcgatt ggatcgttta attctgtatc aggaaagact gcatcttcag
    18001 ttgatttatc ctgcatagct gcatctgtat ttgtttcttc aattgattct tttatttgct
    18061 gatcttctgc agttatttga tgaccgcagt ctggacagat agtattctgc tccatttttt
    18121 tcgatccgca atttggacat tttttcatca cttagcgatc ggctccttta ctaggtttac
    18181 gctaccattt aatctatcat attctatacg tcacgccaat agcttatttt taggatttac
    18241 ttaaaaataa tgaatgaatt tccttcctat agaaaaaaaa gcttgagact gcgtagtctc
    18301 aagctttttt tcttttaaaa taaaccaaac agttttactg atttctcttc tggtcaatag
    18361 tccacgctta ttctaagaaa tcttttaatt gttttgaacg agaaggatgg cgcaattttc
    18421 ttaatgcttt agcctcgatc tgacgaatac gttcccgagt aacaccaaat actttcccta
    18481 cttcttccaa tgttctcgtc cggccatcat ctaaaccaaa acgtaagcga aggacattct
    18541 cttcccgatc agtcaatgta tctagtacat cttccaattg ttcttttagt aactcataag
    18601 ctgcgtgttc tgctggactt gttgcttcct ggtcttctat gaaatcacct aagtgagagt
    18661 catcttcttc accgattggc gtttcaaggg aaacaggttc ttgcgcgatt ttcaagattt
    18721 ctcggacttt ttctgttgga agatccattt ccgcaccgat ttcttctggc gtaggttctc
    18781 ttccaaggtc ttgcagcaat tgacgttgga tacgtatcaa tttattaatt gtttcaacca
    18841 tatgaactgg aatacggatc gtacgtgctt ggtcagcgat tgctcgagtg atggcttgac
    18901 gaatccacca tgtagcatag gttgaaaact taaatccttt gcggtagtca aatttttcaa
    18961 ctgccttcat cagtcccatg tttccttctt ggatcaagtc aaggaactgc atgcctcgtc
    19021 ctacataacg tttagcgata cttactacta aacgaaggtt tgcttctgcc agacgctgtt
    19081 tcgcttcttg gtcgccttct tcgattttca atgctaacgc tacttcttct tccgcagtta
    19141 aaagggagac acggccaatt tctttcagat acatacgaac cgggtcattg atttttacac
    19201 cggttggcgc agaaagatct tctgtttttg cttgttcagc ttttttctca gcactcttca
    19261 agctgtgaat tgatggatca ccattttcat ccaccacact gatacctgcg tcttcaatct
    19321 tttggatcaa tttgtccatt tcatctgcat tcaaagtgaa tggtgtagca agctgattgg
    19381 ataaatcatc atatacaact tgtcgtttgg gtttgttttc tttgatgaaa gctgctactg
    19441 ctgcttcata cgttttttta tctgttccat ttgccataaa agaaggcccc ccttgagtag
    19501 ctatttggct tgttttaact gtttcgttaa attgatgatt tcaatcgtca attcaagctc
    19561 aagctgtttg tttccagttc gtctggcttc ttgctgcatt tgttttttta atgttatttc
    19621 atcagctaag ccagatttgc tgatcacatc tagcaagtct tggatttctc gtggcgaact
    19681 ttcttctgcc accggtaaat attcgatttc caccaccaac cgccttaaat tttcatcttg
    19741 caaaaagtct aaaaactctg caaggttgaa ttcataatgt tgtgagacat atgcatcgaa
    19801 taaaaaataa acttctgcat atgcatcatg aataaactga aattctcgtt cttttaaaat
    19861 attacggaca gaaacttctt taaatgcacg atataataga atctgctctg ccttttctac
    19921 ttgcgtcaaa ggtctctttt tccgtgcagt ttcttgtctc gtaacctgag tgtgttgact
    19981 ttcctgaggt tcttgacgat tttgctgatt tgtccttcga agatcgcgca gttgtttttg
    20041 tatcgtctct ctgccgatct gaaactctgt tgacagttga gatagataca tatcttgttc
    20101 gattggtgaa acaactcggc taagttcaac tagtaattct tcgaggtatt cgatcttgtc
    20161 tttttcatta tctaaatttt tcccttgttt taaataacgt gatttaaaag taaagactgt
    20221 ttcgcgccca tgagccacta attcttggaa agatgcttct ccatacttac ggagatattc
    20281 atcaggatca agcttttctg gaacgactac gacagaaagt gctaatcgac tgttttgccg
    20341 aagcaattca atccctcgat tggttgcttc aaaacctgcg ttgtctccgt catagcaaaa
    20401 gaccaattct ttcgtcagct tttccatttg ttggatctgt tgagctgtta gacttgtccc
    20461 catagaagct aatccagttt tgataccagc ctgccatgca gcaatcacat ccataaaccc
    20521 ttcgaacaac aaaatttctc cgtttttccg gatatcgctt cttgctttat caagattaaa
    20581 taaaacttgt cttttattga acagttctgt ttctggacta ttcaagtatt tgggctgatc
    20641 tttttcctgc cctttttcag gtgcaagcca gcgtcctgaa aaaccgatcg tctggccttg
    20701 agaattacga agtggaaaca tcactctttg ataaaaacga tcagacatac ggccatcatc
    20761 atgcgtgaca aacaatccag agcgttctaa caattcattt gaaattgatt cattcttgaa
    20821 tacttgctga agaaaagaac gctcattagg tgcaaaacct atgttgaatt cttcaattaa
    20881 ttctaaagac aacccacgac tttgcaaata ttctaaagct ggctgtccag cttttgtatg
    20941 caatagcatg tgatgataga tttccgctgc tttttcatga gcagcaatca gtttccccgt
    21001 agcagattca ggattttgga cagctatagt acgctgacgc cattgatctt ctaacggtat
    21061 ctgttcgaag tctgccactt ttaccactgc ttctggaaaa cttagacctt ctagttcttg
    21121 aagaaaagta aacacgtttc cgcctttacc acaaccaaag caatgaaaaa tctgcttgtc
    21181 ttctgcaaca gaaaaagacg gtgtacgttc ttcatgaaaa ggacacagcc ccaagtaatt
    21241 tttaccagac tttttcaact ggacatattg tccaatcacc tcaacgatat tcgtttgact
    21301 gcgtactgtt tcgataacct cttgaggaat ccgttgagcc attttttcac cccctgctct
    21361 attgatatct tttgggttta acagaagata tttcaggaga ataaccggta aaaaatcgca
    21421 ctaactgaaa tcagtgcgat tttaaaggac acaattatac atgtttgatt gtatcatatt
    21481 tcattgcttt ttcaagtata acacatttct atctcattaa gcatcaattt gctactcttt
    21541 tcagtaactg attttgaata tcagccttcc agtacaatac tcgaagaaca atatttacga
    21601 gcatgaatac aaagaagtat cctacgctct ctcccaaccc taagtttact tccaaaattc
    21661 catggaacag cattgcagct acatatatcc ctacgatcgt cgttactgct aggaagatgc
    21721 gcaatgggtt gaagggataa caagctttta caactgccat gcaactgatc ccaatcagca
    21781 agtaatacat caaagtagta gtttcagcat ttccccatgc gaatgttttt ccaagtagat
    21841 acaccgcaat gatattcact actacaagca aggcatttgg taaagcatta ataagtgctg
    21901 taggcaaata acggtaagtg atttttcttt tatcttgttc aaaagataaa aagaaggaag
    21961 gatacccttc aatcgctaaa tcaatcagcg tgatttggat agggataaac ggaaatccaa
    22021 ttgctgtaac ggcacatata atcgataaaa taaatgaata aatcgttttg ataaaaaaga
    22081 tgcctgagac tttcgtcaca ttgttgacca ctcggcgtcc ttcaaacagg acttctggca
    22141 atgtagtaaa atcagagtcc aacaatacca gattcgcaat ctgacgtgtt gctccatcac
    22201 cttctgccat agcaatgctg caatctgctt ctcttaacgc caaaacatca ttcacaccgt
    22261 cgcctgtcat tgcaaccgtt ctgccgcttt ctttcaattc atttaccagc aatttctttt
    22321 gctgcggact cactcgtcca aaaaccgtat agcgatgagc agcttctcgc acttccattt
    22381 cttcagtaat ttgagaaaga tcgacatacg catcataatt cggtaatcct gcacgtctag
    22441 cgatattgga gacagtaaaa ggattgtctc cagaaatcac tttcagatcc acaccttcct
    22501 catgaagata agctagtgtt tcttgagcgt tttttcggat tggatcatcg atttcaaaca
    22561 gagcaaccgg ctcaacaaat gctggttttt cttcgttcaa ttgctgattt ggagcgatcc
    22621 ccaacataag tacgcgatag ccattcgctt gggctgtttt tagactgtcc ggaagccgat
    22681 cttcttccac caaacgttca ggcgctccta cgtacacgac tcccagttct ggaaattcca
    22741 tcgcgcccca tttgcgatca gaagaaaatg cgactttgtt tgtcacatca taccgattag
    22801 aaagctcaaa ataatctctc atagcccgca tagtgatgtt gttatcactg ctttctgcca
    22861 gatacgtccc cataatttct gggatggctt tctcgtacag cggatgtagt gcttctaccc
    22921 gctggatact cattttccct tcagtaatgg tccctgtttt atccaagcat aatgtatcga
    22981 catgggccag cgtttcaatt gaatacatgt cttgaacaag gattcgtttt tttgccagtt
    23041 tggttacccc tgtcgttaat gcaatactta ttagcaatac caaacccttt ggaagcatgc
    23101 ctaacaaagc tgctgcagat gcaataacag aaattttgat agaagcatcg cggatgaaca
    23161 gtgcttccaa aaatagtatg atccccaaag gaataatcac gaaactagtg aatttggata
    23221 ctttgcgaat cgaatctaca agttcagaac gaatagcttt gtgagtcttt gcctcgctag
    23281 tcaagcggac agcataatta tctgcaccta ctcggataac ttcagccatg acagaaccgc
    23341 ttgtcaaaaa gcttccagaa agcaattcag ctccagtttc tttgacaatc aaatcagatt
    23401 cgcctgtcaa aagagcttca tttgcttctg cccgtccaga tataacctgt aaatcggctg
    23461 gtatctgttc tcctgctccg atttttacca aatctcctaa taccagctct ttagtagaaa
    23521 tcgattgttc tttaccgtcc cggatcacta gtacttctga ttgggaaaca atcgataatt
    23581 tccgtacaag atttcttgca tgtatttctt gataaattcc aataacgata ttgacgacaa
    23641 taattgctaa atacgccatg ttggaatacg cacctacaaa taacagacaa atcccaatac
    23701 caaagttcag aaaattgaat aacgtcaata tattatcgct gaatatttgt tttgtacttt
    23761 ttgatgcatc ttcctggtag tcattttgct ggccagaagc cattttctga actacctctt
    23821 gctgtgtaag tccattcatt ttctttttct ccattttccg ccaactttca aaaataatca
    23881 cgtgtttaag tctagcgtgt tccaagatta aaaacaactt gtttttataa aatttataga
    23941 aaaacacacg aatgatttta caaaaaagat gccaaccttt ttgtttgaat cacccgtgtg
    24001 ctgtttttat tatcaatcta tctttactta tattgttcct ccaaacggct catccaccaa
    24061 cctagtgctg taccggctat aaaaagaaca ggacaagcta gtaccccagc aactcccaat
    24121 cccgcgtaat cggtaggaat gatcataatc gttgaagcaa aaactacacc taaaatgaaa
    24181 tggaatagct tgctatatgc ctttgagaaa atgtaatcca tgatttttga caatccaaga
    24241 acacaaagaa tcccaccaat tccgatcggc acaatcactt caagtcgtac ttctttaaat
    24301 ccgtcagcca tcgctttata caatcccata tacaccaaaa aattagaagg gctcaatcct
    24361 gggacgatca tacccaaacc aatcaatccg ccggcaatca gccatgttcc aaaattctga
    24421 tcgacttgcc cgtcaaataa ttgagcgccg tataataaaa acaaataagc cagaacaaaa
    24481 gtaacaacca tgatgatcac atcagaagta tctcttcctt ttttccctgc ttctttccat
    24541 aacgcaggaa cagttccagc gatacatccg acaaaaaacc ataatatcgt tgtttcatac
    24601 gcacctaata aaaaactgac taaaaaagaa agtagaaaga tgcctgtcac tccgcctaga
    24661 ccaacaggca gaaaaaacaa aacattttct ttgaaatttt ttgtaaggtg ggctaaaaaa
    24721 gaaatcagcc gctcatacat gccaaagaca gctgctaatg caccaccgct gactcctggc
    24781 aagataaatc ctgaaccgat aaacattccc ttcacaaacc gtaacatcca gtctttggtt
    24841 gtgtacccca cttcttgatt ttccattttt tgcctttttt ccactatttg cgtactcctt
    24901 ctttcattta attttattca tgattgaaca tttcctgcta ttttacttaa agactttttc
    24961 ataggtctct attatttttt cattcatttt gacaatatca ggataaaaca tgttacctcc
    25021 attatgatag agatagccgc cattgtaaag caaggactgg atccgccaat atcggtattg
    25081 tttcccttcc tcatttccta aaagtgggct cagcacatct ttagaatacg cttctgctaa
    25141 ttctactgtg ttttctccgc catgattttt tacataggca atataatctt tcccaaaatt
    25201 atatgcttgg acagctgtcc ataaatcgca tccttgtttc tttgcttcta ctatcatttc
    25261 cgccaaatat ttgacacctt gatcaatact gtcagctgga ttatcaatga tctcagcttc
    25321 tccatgcaga ctttccgagc tctgcatgag atctgtccct tttccttttg attcggtcaa
    25381 tattatcgcc ttgatcaaat tctcgtagtt ttccatatga taattttttg cagctgttgt
    25441 tatttctatt tgatagcttt ccactcgttt taccgaacga taagttcttc ctcataaaaa
    25501 caacaccgca ccaataaccg tcagaatgat catgtaaaaa agaatacgga taatagataa
    25561 tcgttttcgc ttcatttcat cacctagtta ttttgacatc tttttttatc ttactatttc
    25621 tttatcttct tggctatttc ttccttgatt tctgtgtacg ccttaagaaa aaatgaattt
    25681 tcctgtattt tttgacatct tacgaaaatg atcgttgttt ttcagtaaaa acaattgccc
    25741 aatgactgat ataatcgtta tactttacac agtaggtgat tatgtgaaaa aagaaaagaa
    25801 atatgcaaaa atgccagatg ggagcgaaat ttactatgaa aagagcggtc aaggcttccc
    25861 tctcttttta ctgcatggca atgacggcag cggccgcttt ttttcagaac aggtccctgt
    25921 actcgaacgc tactataccg tgtatctagt agatagccga ggacatggtc gttcgacaaa
    25981 cgaagcatct atgttgaatt ttcagttaat ggccgaggat ctgaatacga tcatgttgct
    26041 ggaaaaaatc gatcaggcag attttcttgg atttagtgat ggagcaaatc tagcactggt
    26101 atttgccagc agcttcccta aaaaagttca tcgattgatt ttaaattctg gaaacacgct
    26161 tgttaaaggc gttcgttttt ctgccagagt catcagtaat attcattatg catgggtatg
    26221 gttactctct ttatttcgcc caagtcttcg caaaaatctt ttagttatca aacttttgct
    26281 gcatgacatc gggcttacag aaaatgattt aaaaaaaatc aactccccca ctttgatcat
    26341 cgtgggaaaa aaagatgtaa tcaagctaaa acattctttg tatatagcta aaactatacc
    26401 aaaagcttcc tttgtgcttg tgaaagaaca aggacatgaa ttagctagaa aagatcctga
    26461 acgcttcaat cgagaagttc ttcaatttct ttctgaaaca taactattag gaatagaagg
    26521 tgatttattt gttaaaaaat accatacaat ggctgaaaaa ccacctagga ctgttcaaaa
    26581 caatcttttt gatttctgtc attgtcatta ttgtcggtga attgatgtcc atcggtaaaa
    26641 ctctatctat ccagcaatta ggagaaacgt ttgccactat acctgtatgg aaaagcggac
    26701 taatgctatt gattggtctt atctctgtgt tacctatggt tggttatgat attattttga
    26761 atcggatgct tgaacaaaag cagaatcctc gttacctgtt tgagacaagc tggctgatca
    26821 atacgatcaa caatattgcc ggtttcggcg ggtttgttag tgtggggctt cgctctgaac
    26881 tatatggaca aaagaaagag agcagaaacg tgatccaagc attatcgaaa gttttcttgt
    26941 ttttgatggc tggactttct atttacagtc tgctttcttt tttacttgta gtcttcacgc
    27001 cagttgctcc ttttttgaag caatattgga tatggttgat cggcggcggt ctatattttc
    27061 ctgtcgtctt tttatttact actttcaaaa agaaaggatt ccttggtggt acctcactta
    27121 aaactcaagg acagctattg ctagtttcat tgttggaatg gaccggtgtc ctgtttagtt
    27181 tcctttctgt tggttattta atggaaatcc ggattgatct gtggcaaaca attccattat
    27241 tcattgctgc ttcagtgata ggaatcgtgt ctatgattcc aggagaaatt gggagtttcg
    27301 atgtaatgat gattatcggg ttgtccgcta ttggtgtgcc aagagaaata gtcgttgtgt
    27361 ggatcttgct ctatcgcctg ttctactaca tcattccgtt tttgattgga atcgtctttt
    27421 tcttcaaaaa tatcggttcc acttttgatc agcgttattc tggtatccct aaacaattag
    27481 caacagaaat tgcgcataaa atcgtggttg tcttattata cttttctgga atcatgctag
    27541 tactttctgc cactatcccg caagctttta cagagtttcg ctggcttcat agtttgaacc
    27601 cattgaaatt tcattttatt atccaatttc ctagtatact attgggattt cttttaatca
    27661 ttatgggcag agggatcgca gcacgtgtga aacgagcata tttgcctaca atcttcttga
    27721 ttgttctagc tttactttat gttttattaa gtgattttag tttcacaccg gtggttttct
    27781 tgtctattct gcttctgatc attcttgctt ctaaaaacga attatttcgg gaacaattga
    27841 tctattcatg ggagtggcgt acgatcgatg gaatcattat tggtgcactg tccttgcttt
    27901 acatcgttat tggggtatac aatctgccgg atttccctca tcggcgtcac cattttattt
    27961 cctttttctt atttccttct gaaaagattt ggttttcggg attgttggcc atcatcgctg
    28021 ttagtttcat gatcgttcta tttgttcatt tccttcaagg agaaaagaaa cagattggcg
    28081 aagcctttaa tgaagaaaag gccctgaaga tccttacaac ttatggagga aactccgata
    28141 gtcaattgat cttcttaaaa gataagcgga tgtttgccta tgaaaaagac ggtgaaccaa
    28201 ctgttcttct ccaattcgct tgcttcaata ataaatgtat tgtaatgggt gatccttctg
    28261 gtaagaaaga agattttcca gaagcaatcg aagcttttat cgaagaaaca gatcgactat
    28321 gctatttacc agttttctac gaaacaagcg aagagattgt tatgattttg catgaattcg
    28381 gctacgattt cattaagatg ggggaagaag cttatgtaga cctgaatagt tttacaactt
    28441 cagggaaaaa aatgaagggc actcgtgctg tcttgaatcg gatcgaacga gaaggattta
    28501 catttgatgt cttacaacca ccattttcta ctgagcaaat gagtactttc aaaaatatct
    28561 ctgataattg gttgggttca cgaaaggaaa aagggttttc tttaggcttt ttctctgaag
    28621 attatctaca aagagcgcct attgcagttg tcaaaaatac ccaagaagaa attgtcgctt
    28681 ttgcaacgat catgcctact tacacgaaca ataaagtagg aacgattgat ctgatgcgat
    28741 atgattctaa aaaagcacct tctggcagta tggatttctt gttcttgcat ttgtttgcct
    28801 atatgaaaga agaacatatc caatggttca atttagggat ggcccctctt tcaaatgtcg
    28861 gaacttccag aaagagtttt ttacaggaaa ggattgcata cttggtttac gagtttggtt
    28921 ctcattttta ttctttccat ggattaagag aatataaaag caagtacgct acaaactggg
    28981 tctcacgtta tactctatat tctagagata gttggattgc atatgttatg attgctttgc
    29041 tgattattga taatgcgcca gttgagcaga cacaaggtag aataagtggt ttgaaaaaat
    29101 ggatacgaag aaagtattaa aaactgcata ccgatagatg aacactctca tgatgaataa
    29161 aagagactga agtaaaacga aagttcatgc ttctacaatc tcttcttata caattgaaga
    29221 acaaagagcg gtccaaacag aaatcctgtt tggaccgctc ttttatttta aacatttttc
    29281 attaccaaaa tattcgagtc gcgtttctta tgcttcgatc tctgtaacga tacctgaacc
    29341 tactgtccgt ccgccttcac gaattgagaa tgtcgttccg ttttcaacag cgattggatg
    29401 gatcaagtca acatcaatcg tcacgttgtc accaggcatg accatttctg tatcttctgg
    29461 caatgtgatt gttcctgtaa catcagttgt gcggaagtag aactgtggac gatagttgtt
    29521 gaagaatgga gtatgacgtc caccttcttc ttttgtcaac acgtacactt ctgctttgaa
    29581 ttttgtatgt ggagtaatgg aacctggttt agcaagtact tgtccacgtt cgatatcgtc
    29641 acgttggatc ccccgtaaca acacgcctac gttatcccca gcttccccgt aatctaacgt
    29701 tttacggaac atttctacac ctgttacaac tgctttttgt gtttcaggtt tgatccctac
    29761 gatctctacc tcatcaccga cacgaacagc accacgatca atacgacctg aggcaacagt
    29821 tcctcgacct gtaattgaga agacgtcttc cactggcaat agtaatggtt tatctgtatc
    29881 acgttctggt gttgggatat attcatctac tgtatccatc aattccataa tagcagcttc
    29941 agcatctgga tcgccttgca atgcttttaa tgcggaacct ttgatcacag gagtgtcatc
    30001 gcctgggaaa ccatattcgc tcaataactc gcgaacttcc atttctacca aatcgatcaa
    30061 ttcttcatca tcgactaaat caactttgtt caagaaaaca atcaggtatt ttacaccaac
    30121 ttggcgtgac aataaaatgt gttcacgtgt ttgaggcatc ggaccgtcag ttgcagaaac
    30181 aactaagatt gcaccatcca tttgtgctgc ccctgtaatc atgtttttca catagtccgc
    30241 gtgtcctggt gcatcaatat gcgcgtagtg gcgtttttct gtttcatatt ctacgtgtgc
    30301 ggtattgatc gtaatcccac gttcacgttc ttctggagct gcatcaatac tagcatagtc
    30361 ttgaggattt gctaggcctt ttttgcctaa tactgtagtg atcgcagcag ttaaagtagt
    30421 tttcccatgg tcaacgtgtc caatcgtacc aatgttaacg tgtggtttac ttctgtcata
    30481 atgttctttt gccataattt acaaacctcc taaataatat agatcactga aaaatttcag
    30541 ctctcacctt tttattatag tctttttttg actaaatcaa aaagaatacg tccgacttac
    30601 tttttgtaag attcgaacta agcttattat acgtcaatat tggtcaaagt caactaagag
    30661 cactcgtctg tcttatacgc gaaaaaagta ccttttataa ataaaaaaat gtgttttttg
    30721 agaaaaactt caagatagtc cttaactttc ttttgaagca ataagaacaa aatgaggaaa
    30781 agtttaaaat tcagctgttg ccaacaactt tcaatagacg aaatcttcta tttcgttaat
    30841 aataaggaaa gaggtgaagt acatgaaaaa attaattggc gtacttgtcg ttttaggcat
    30901 atttctcggc ggaagttttg cagcttatca ttatttttac ggcggcgaag cttattatac
    30961 aaaaatcacg acgaatggcg aaatgtcagc tacccaagca gataacggag agaaattcac
    31021 gacttatacc tacaagcaag cggcttataa taaagatggt gaaaaaaaac aggtgacgct
    31081 tcgcgaagaa agagaacatc cattaaagat gaatgcgtat cttaaactca aagtcaatcc
    31141 tcgtaaaggt gtattaagct gggaagaaat aaaggcttct gaagtgccta aaaatgcggc
    31201 agaaaaaatc gataattagt aaatggtctt aaaattttat tagataaaaa gaggctggga
    31261 cagaagcgtt taactccaag aaataagaag gagttgcttc tgcttccgcc gtttatacgt
    31321 gtttagagcg tgagacaaaa gtgttcttta cttttgtctc acgctctttt tttgttatat
    31381 tcgtcttttc cgatccttct cttgacacaa ttcatttaac tgatcactgg tacttgaaca
    31441 cctaatattc tagtcatttt tataaacgat tcaatacttc atccacattt ttgatcatca
    31501 cggatatcgt accatccgga ttattcacaa attcaatcaa atctgggttg cgatatacat
    31561 ctactggtac gatcagttcg atcccgtttg atagcttgaa tttttgtttt ccaaattttt
    31621 tctcagaaat ttcttgtact tcttttacag gaggtgcttc tgggacaaat ccttgctctt
    31681 gtacttcttc tttaaaagcc atttttgccg tgatgttttc cttgaagact ttttccgcaa
    31741 tcatctcatg atccaaccga cctttttctt ctatcgtatc atagacagct tctttcaaat
    31801 cagccatgat atcaaattct tctgtctcaa atttttttcc aagatgcttg gctacttttt
    31861 ggatcacttt tacattttct tctaaagaag gtgcaggaac actttcgatc actcttccag
    31921 aaaaataaag ctcttttttg ccagaaaact catatttttt ttcaattaat tcgtaggtcc
    31981 aatcagtcaa attcacagcg aatgcttcat ctgctttttg tgttttcgcc cctagaattg
    32041 ctcgattcaa aatcaagcgg ttgtcgatcc ctgcttcgtc tgcttcaaca aagtgagtgt
    32101 aagcctcacg ataattgact ttcaataaag ataagtacat cactgtatct aattcataca
    32161 agacaacaaa tacatctgca ctaggtgctt cttcactttc ttggtagata tcgaaccacc
    32221 gctgaacgat tgcttcactt gcttccacaa aattttcttg agcgatttta agtgattcaa
    32281 cgatcatgct ttcttctgct agttgtccag tttttgtttg agcagaagag attttttgga
    32341 tcttcttttg aagaaaatca cgaatatatt cttttgtcag atccagctct ttttgtgaaa
    32401 agactggaga accagtttct ctgtcaataa tatgcagaat tgcttttttt aaatagatat
    32461 ccattttctc attcccttct gtcttagttt acggaaaaaa aatcaaaaat accagaatca
    32521 aaatcatttt cttttaaaca aaaatttcaa gagtagaaac aaaatggatt ctttttttcg
    32581 aaaaatgcgc tacacttata gttgaacgaa taaaaaagga gctgaaagta tgaattcatt
    32641 aacaagcact tatcgtctat caaatggtta cgaaatcccg gtagtaggat tcggcacatg
    32701 gcaaacacct gatggggatg tcgctgtttc ctctgttaaa gaagcgctgg ctgcaggtta
    32761 tcgccatatc gatactgccc aaggatacaa gaatgaagaa agcgtcggcc aagcgattaa
    32821 ggaaagtgga attcctagag aagagatatt cttgacaaca aaattatgga atgcaaacca
    32881 cagctatgaa cttgtgatgt cttcttttga agaatcattg aagaagctcc aaacagatta
    32941 tttagatctg tttttgatcc actggccaaa ccctgttgct tttcgtgata attgggaaca
    33001 agcaaatgca gatacatggc gagcatttga agaactgtat gaagcaggta aaatcaaagc
    33061 aatcggtgtg agcaatttct taccccacca tctagataca ctagcaaaaa cagcaaaaat
    33121 tatgccgatg gtcaatcaag ttttccttgc accaggcgaa ttacagacaa ctgtagttga
    33181 gtatgcaaaa aaacatgata tgatcctcga agcatatagt ccattaggca ctggtaaaat
    33241 cttcgatgtg cctgaaatga aacaaatcgc tgaagcacat gacaagacga ttgcacaagt
    33301 tgctttgcgt tggtcgctgc aacacgaatt ccttcctctt cctaagtcag tgacaccaag
    33361 cagaatcaaa gaaaatactg aattatttga ttttgaatta acagaagaag aaatgaaaca
    33421 aatcgatcag ttagatggtg tagtcggcaa agcaaaagac ccagatacta cccaatttta
    33481 agtcgaaagg tgattttatg gatccaatcg aacgcttgaa ttctctctcg gaagaagtta
    33541 cccagacttt tcattccgat tttgtctttt tgatcgatgc agagaaaatc caacattttc
    33601 ctgcaagaaa ctggacacat gatcaaatca tcgaagaact gaaaaaacgg ttcgatcatt
    33661 cgctaatggt caaaccctgg cacgaacatg aagtcattta ttcacctgaa ctacctgttt
    33721 ttgccttgat accgaaaaaa tagaaagaat ggaacggatt atgtatatat acataatccg
    33781 ttccattttt tatttttctt tcaaaaaacg ggaaaatacg caaatttttc tgttgtaatt
    33841 tgcgtatacg caagtttttt tgcattactc cttttcattt ggctgttttt ttcttataat
    33901 cgaaagggta tgagcgaagg agagaacata tgaagaaaaa acagaaacaa aaattattaa
    33961 atcaattccg tccttcattg gatggtgtaa gaggacaatt attccgttct ctagaagaag
    34021 agagcttgcg acgttatggt ttgccgttac aagtcatgct tgatcccaaa aaccgtcaaa
    34081 tcttaacgat cggattagct gggaaaacaa atgaagatac acggatcaac gtgccaatcg
    34141 atgacaactt caatactgta ttaaagagaa ttcgttcagg agaaaacggg attttcgaac
    34201 gattccgtga caatcttctt attgaaatcg tgtcttactg gaatgatcaa cgattgaaaa
    34261 acgatgaacc aactgcgcaa gctgttgcga caccagttac agaagaaaca gtcagtgtgc
    34321 cagaagaaaa aacggaaaaa ccaaaagcgg acacaactga aaatacacgc tcaactgata
    34381 cgaatgccgc tttaagtttt gctgattttt caaaagccgt tgctgagtat cctaaatttt
    34441 acacagaaca aaatgaacat gaagtagtta ttaatgaaaa aaatgctgat gaacctcgta
    34501 aattagcaac tatttctatg actactgaaa atgagttcgt tatcgaaaaa gcactcgaac
    34561 ggaaatacaa agtcaaattg actttgattc ctttgatcga acaatttgca gcgacagcga
    34621 ttactgatcg ataaaaattc tatttgtcat aaaaggctgg gatttaaaat cccagccttt
    34681 ttagtcatat aataatttct acagcaagta aaaagaaatt ccttctaaca tcaggctcaa
    34741 atatcagctt gacctgtcca acaaatcacc tatgatccta caatgttagg cgacttctct
    34801 tctacctgaa gatatcttgg agttgcctga tttcttaaga tgcctaacct taactataaa
    34861 aaattctaat aataaacata ttttctgata gagaaaaaa
//
LOCUS       DAIGWC010000023        34662 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.023, whole genome shotgun sequence.
ACCESSION   DAIGWC010000023 DAIGWC010000000
VERSION     DAIGWC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.023"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(313..2205)
                     /locus_tag="NOB74_001130"
     CDS             complement(313..2205)
                     /locus_tag="NOB74_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220331.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2202..3929)
                     /locus_tag="NOB74_001131"
     CDS             complement(2202..3929)
                     /locus_tag="NOB74_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220332.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3945..4595)
                     /locus_tag="NOB74_001132"
     CDS             complement(3945..4595)
                     /locus_tag="NOB74_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCI1220333.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4799..5095
                     /locus_tag="NOB74_001133"
     CDS             4799..5095
                     /locus_tag="NOB74_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI1220334.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5287..5907
                     /locus_tag="NOB74_001134"
     CDS             5287..5907
                     /locus_tag="NOB74_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HCI1220335.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5999..7165)
                     /locus_tag="NOB74_001135"
     CDS             complement(5999..7165)
                     /locus_tag="NOB74_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI1220336.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7177..7530)
                     /locus_tag="NOB74_001136"
     CDS             complement(7177..7530)
                     /locus_tag="NOB74_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCI1220337.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7658..8680
                     /locus_tag="NOB74_001137"
     CDS             7658..8680
                     /locus_tag="NOB74_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HCI1220338.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8699..8860
                     /locus_tag="NOB74_001138"
     CDS             8699..8860
                     /locus_tag="NOB74_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220339.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9119..9553)
                     /locus_tag="NOB74_001139"
     CDS             complement(9119..9553)
                     /locus_tag="NOB74_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220340.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9663..11522)
                     /locus_tag="NOB74_001140"
     CDS             complement(9663..11522)
                     /locus_tag="NOB74_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI1220341.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11640..12800)
                     /locus_tag="NOB74_001141"
     CDS             complement(11640..12800)
                     /locus_tag="NOB74_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HCI1220342.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13107..14531)
                     /gene="araA"
                     /locus_tag="NOB74_001142"
     CDS             complement(13107..14531)
                     /gene="araA"
                     /locus_tag="NOB74_001142"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HCI1220343.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14547..15245)
                     /locus_tag="NOB74_001143"
     CDS             complement(14547..15245)
                     /locus_tag="NOB74_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCI1220344.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15202..16863)
                     /locus_tag="NOB74_001144"
     CDS             complement(15202..16863)
                     /locus_tag="NOB74_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HCI1220345.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17081..18481
                     /locus_tag="NOB74_001145"
     CDS             17081..18481
                     /locus_tag="NOB74_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HCI1220346.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18733..19812)
                     /locus_tag="NOB74_001146"
     CDS             complement(18733..19812)
                     /locus_tag="NOB74_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1220347.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19898..20857)
                     /locus_tag="NOB74_001147"
     CDS             complement(19898..20857)
                     /locus_tag="NOB74_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCI1220348.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20869..22380)
                     /locus_tag="NOB74_001148"
     CDS             complement(20869..22380)
                     /locus_tag="NOB74_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCI1220349.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22402..22966)
                     /locus_tag="NOB74_001149"
                     /pseudo
     CDS             complement(22402..22966)
                     /locus_tag="NOB74_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            complement(22972..23835)
                     /locus_tag="NOB74_001150"
     CDS             complement(22972..23835)
                     /locus_tag="NOB74_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1220350.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23849..24745)
                     /locus_tag="NOB74_001151"
     CDS             complement(23849..24745)
                     /locus_tag="NOB74_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1220351.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24920..26209)
                     /locus_tag="NOB74_001152"
     CDS             complement(24920..26209)
                     /locus_tag="NOB74_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1220352.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26181..27698)
                     /locus_tag="NOB74_001153"
     CDS             complement(26181..27698)
                     /locus_tag="NOB74_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCI1220353.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27896..28786
                     /locus_tag="NOB74_001154"
     CDS             27896..28786
                     /locus_tag="NOB74_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HCI1220354.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28859..29683)
                     /gene="nadE"
                     /locus_tag="NOB74_001155"
     CDS             complement(28859..29683)
                     /gene="nadE"
                     /locus_tag="NOB74_001155"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HCI1220355.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29695..31167)
                     /locus_tag="NOB74_001156"
     CDS             complement(29695..31167)
                     /locus_tag="NOB74_001156"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HCI1220356.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31804..32166)
                     /locus_tag="NOB74_001157"
     CDS             complement(31804..32166)
                     /locus_tag="NOB74_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCI1220357.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32389..33141
                     /locus_tag="NOB74_001158"
     CDS             32389..33141
                     /locus_tag="NOB74_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI1220358.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33281..34204)
                     /locus_tag="NOB74_001159"
     CDS             complement(33281..34204)
                     /locus_tag="NOB74_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1220359.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34219..34491)
                     /locus_tag="NOB74_001160"
     CDS             complement(34219..34491)
                     /locus_tag="NOB74_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220360.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10231 a         7214 c         5978 g        11239 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      301 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      361 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      421 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      481 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      541 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      601 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      661 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      721 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      781 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      841 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
      901 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
      961 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1021 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1081 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1141 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1201 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1261 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1321 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1381 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1441 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1501 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1561 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1621 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1681 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1741 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1801 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1861 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     1921 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     1981 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2041 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2101 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2161 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2221 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2281 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2341 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2401 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2461 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2521 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2581 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2641 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2701 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2761 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2821 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     2881 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     2941 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3001 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3061 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3121 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3181 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3241 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3301 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3361 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3421 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3481 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3541 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3601 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3661 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3721 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3781 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3841 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     3901 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     3961 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4021 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4081 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4141 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4201 tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag
     4261 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4321 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4381 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4441 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4501 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4561 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4621 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4681 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4741 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4801 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4861 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     4921 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     4981 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5041 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5101 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5161 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5221 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5281 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5341 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5401 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5461 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5521 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5581 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5641 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5701 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5761 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5821 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     5881 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     5941 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6001 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6061 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6121 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6181 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6241 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6301 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6361 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6421 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6481 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6541 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6601 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6661 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6721 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6781 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6841 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     6901 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     6961 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7021 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7081 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7141 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7201 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7261 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc
     7321 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7381 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7441 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7501 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7561 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7621 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7681 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7741 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7801 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7861 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     7921 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     7981 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8041 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8101 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8161 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8221 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8281 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8341 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8401 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8461 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8521 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8581 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8641 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8701 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8761 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8821 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     8881 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     8941 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9001 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9061 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9121 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9181 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9241 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9301 tatgaatgcc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9361 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9421 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9481 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9541 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9601 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9661 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9721 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9781 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9841 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
     9901 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
     9961 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10021 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10081 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10141 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10201 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10261 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10321 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10381 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10441 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10501 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10561 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10621 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10681 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10741 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10801 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10861 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    10921 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    10981 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11041 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11101 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11161 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11221 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11281 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11341 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11401 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11461 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11521 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11581 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11641 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11701 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11761 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11821 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    11881 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    11941 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12001 gtcgatcccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
    12061 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
    12121 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
    12181 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
    12241 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
    12301 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
    12361 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
    12421 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
    12481 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
    12541 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
    12601 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
    12661 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
    12721 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
    12781 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
    12841 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
    12901 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
    12961 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
    13021 agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa tctcttctta tttcttaaaa
    13081 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
    13141 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
    13201 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
    13261 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
    13321 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
    13381 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
    13441 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
    13501 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
    13561 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
    13621 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
    13681 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
    13741 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
    13801 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
    13861 tcgtctgata cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
    13921 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
    13981 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
    14041 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
    14101 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
    14161 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
    14221 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
    14281 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
    14341 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
    14401 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
    14461 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
    14521 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
    14581 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
    14641 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
    14701 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
    14761 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
    14821 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
    14881 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
    14941 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    15001 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    15061 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    15121 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    15181 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    15241 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    15301 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    15361 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    15421 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    15481 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    15541 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    15601 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    15661 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    15721 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    15781 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    15841 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    15901 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    15961 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    16021 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    16081 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    16141 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    16201 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    16261 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    16321 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    16381 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    16441 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    16501 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    16561 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    16621 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    16681 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    16741 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    16801 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    16861 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    16921 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    16981 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    17041 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    17101 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    17161 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    17221 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    17281 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    17341 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    17401 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    17461 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    17521 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    17581 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    17641 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    17701 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    17761 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    17821 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    17881 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    17941 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    18001 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    18061 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    18121 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    18181 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    18241 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    18301 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    18361 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    18421 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    18481 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    18541 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    18601 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    18661 gatgacaaaa gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta
    18721 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    18781 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    18841 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    18901 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    18961 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    19021 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    19081 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    19141 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    19201 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    19261 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    19321 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    19381 aggctcaacg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    19441 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    19501 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    19561 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    19621 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    19681 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    19741 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    19801 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    19861 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    19921 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    19981 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    20041 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    20101 ttttttcaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    20161 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    20221 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    20281 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    20341 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    20401 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    20461 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    20521 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    20581 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    20641 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    20701 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    20761 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    20821 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    20881 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    20941 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    21001 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    21061 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    21121 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    21181 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    21241 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    21301 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    21361 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    21421 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    21481 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    21541 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    21601 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    21661 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    21721 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    21781 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    21841 cttagccccc acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc
    21901 aaaaggcttt ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa
    21961 attacaatat tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt
    22021 gaatatcggt ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga
    22081 atttggttct atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc
    22141 tacagtatcc acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc
    22201 taattctaat tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt
    22261 ttcatggccc ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga
    22321 gccaaacagc cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac
    22381 ttcttcgtcc aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag
    22441 tttccatacg ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac
    22501 aaatcctaat aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca
    22561 tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat
    22621 ccaggataaa agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac
    22681 gattgtctgt tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact
    22741 aaggaacaag ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt
    22801 tcctgatccc tcacctttcc attgcgccat tacataaaaa aacagcacat gtagcaggca
    22861 cgatagtaat aacaggcaaa cacacgatta cccagagaat acctaataag atgtaatcag
    22921 aaaccacaat caactgtcca taaagtttag tctcaactat tttcatcttc ctcactcttt
    22981 cattccagac atagctgttc cttgaacaaa atatttctgt gcaaaaatat aaaccactag
    23041 taatggcagc attgaaataa ccgttccagc cattacaggt ccataaaaag aaatgttctg
    23101 ccctgtaaat aaagctaacc ctgctggtaa agttctcatt tttgaactac ttgtcaatat
    23161 caatggataa agcaagtcat tccaactatt catcagcgtg aaaatcccta atgataaaag
    23221 agtaggtttg ctcaatggca acatgatttt caaaaaaata ttaaactcac ttaatccatc
    23281 aatgcgtgct gcctcttcca aagaatctgg taaagtaata aaaaaggaac gcatcatgaa
    23341 gataccaaat gcagttgtca tacgaggaat gatcaaacct gcataagtat caagcatgcc
    23401 aagcaaattg acttcaataa atagaggaat catgaagact tggaatggga tcatcattgt
    23461 cagcaaaacg aaatagaaca aaactgattt tcctttgaaa cgcatacgag caaatgcata
    23521 ccccgcaaga gaatcaaaga atacagaagt gatcactgtc cctccagcaa aaatcactgt
    23581 atttttgatg taatctaata aagggatcgt tgtccaaacc ttaatatagt tatctagggt
    23641 atagctatct gcaaatattc taggcggaaa tgagataatg tctttttcgt gtttaaaaga
    23701 agaaataatc agccacaaaa aaggaaacgc aataaccaac aatataacta gcatactaat
    23761 cgttcgaatg atttttttac cactaactgc ttttcgacta ttcacagtaa ctgtaatcga
    23821 gctttctggt gccatacagg tttccctcct atttcatttg tttttctttc cgtgacatgt
    23881 acacattagt ggagatagct atagttgcaa caatgataaa caaaaccgaa gacagtgctg
    23941 atgcatagcc caattcataa ggtgctgtaa atcctcgact gtaaatatat tgaacagctg
    24001 tttctgtctt aaattgtggg ccaccagcgg ttgcaacata tacttggtca aacacttgca
    24061 tcgaaccaat cagattcgtt aaaatacaaa aacctaagga gggaacgatc tgaggtagcg
    24121 taatgttaaa aaactgctgt cgatttgttg caccatccat ttgagcagat tcatacaaag
    24181 agggagagat tccctgaata gcagtcaaga gaatcgtcat agtaacacca aaattcttcc
    24241 aaacagtcat gatggctacc gtcggcatag caagggttgg atcgcgaaaa aattgaggga
    24301 tcggcaagcc gacttgtgaa aacaagtaag gaatcgcccc tacattcgga tcaagcaaca
    24361 tagaaaaaat aatcgcaatt gacgtcaatg aacaaataac tggaatgtaa aatgtcgaac
    24421 gacaaaaacg attgaatctg gtatttttag ataatgctac tgctgctaat aaaccaacga
    24481 taatttgtgt tggcgtttcg agtacggtga aatataaaga atgaatcaac gaattaactg
    24541 ctcgttcatc actaaatata cgtgtgaaat tttcaaaact tacaaaattt cttgatgtaa
    24601 agaaaatatt caaatctgta aaactaatag caaatgttcc taaaagcggt atgacagtaa
    24661 ataataataa aactaaaaaa gatggagtta aaaacaaata cgcagcacga tcaggacgat
    24721 tccaatattt ggtgaatccg ttcatatagt ccacctcatc tttcattttg ataaaatata
    24781 caatcttggt ttaaacgaat ctgaataaga tatccgaaca atcgctgtga tttttgcaat
    24841 aacacctatc tgcaaatact aggtcgatca ttcagatatc tgtatcttgc caacagtcta
    24901 tcctgtataa agttctgtac tatttttgca gtaattgatt gatggcatca tctgcatcgt
    24961 tcatgagtgt ctcaggatct tctcctgcta ataatttttc aatcagtgga ttgatgatat
    25021 cgttattgat cgcagagatt tgggtaaaac ctggtaaata tggctctgca tagtccattt
    25081 gtttcgataa ttcagataca ataggatcat tttttacttc ttcatctttt gctactgaat
    25141 ccaagtaggc aggaaaacca ttttcgatac tccatttttt accaatttca gttgtattcc
    25201 aatatttcaa aaactcatag acagcttctt ttttattatt atctgtactt gccggaatgg
    25261 catatcctac gccatctaaa atagctgttt ttttgtctga atcactccct tgtggtaagg
    25321 tagtcacatt ataatcaatc tcgtttgctt tcaatccgtt atttaaccat ggcccattga
    25381 tttcaatggc tagttgacca gcattcatta aattgtccat ttcggcgcca gaaatcgatt
    25441 ctggaccagt cttgtctaca tggatcattt tttggatcgc ttttaacgtt ttaaggttct
    25501 caggagacgc aaattcagac ttagtataat catcgttcac taatttaccg ccatttgcta
    25561 acatccagtt atataacggt gcagttccat ccttattgaa gacaaaacct gatacatttt
    25621 tactactatc agttaatttt ggtgccattt ctgtcaattc ttcccaagta gtaggtggtt
    25681 gttcagtatc taatccagct tgtttaaaca aatcattatt ccaatacata tacatgcctt
    25741 gtacctgcat ggggacaaaa tactgtttac cttctacttc acctaattca atagccgttt
    25801 ctttaaaatc agatttatct actccatcat attcccagaa atcgtctaat ggttgtaccg
    25861 ctccgttttc tacatactgt gcaaaatctg gataatttaa tgcaataaag tcaggtgctt
    25921 ttttagaaga aatcgctgta ggaagttttt cattcaaatt ggcccaagtc atgatatcca
    25981 tttcaatttt gatgttttta tcatttgttt tattaaattc attaacgatt tcttgcaata
    26041 tttcaccatc agatgcagta aacccattcc aaaaagtcaa agtcacttct ttatcagaat
    26101 cagattctgc tgaacttccg ccaccgcaag ctcctaaaat acctgttgca gctaccaaca
    26161 aagagccaat taaccatttt ttacctttca ttttttgttc ctccttcatc tgataaacga
    26221 catctgacca cattccaaga tagcggtttc aataaacaat tgattttccc atcttcagct
    26281 tttacatttg ttgaatgact tggttttact tgttcacttt taggaagatt agttgctttt
    26341 gtatcaaatc cactcatttc agaaaaatca atcactccct ctaatgataa ttcagacaag
    26401 tgaacagtta gattcatttc ttcttctcca cggttaactg caaatatgac aagttctttg
    26461 tcatttatta cggctatact ttctaaatac ggcacttctt caaaatcttc cgtcgcatag
    26521 tttgctgaac gaatttgtgg gcttaacacc tctccttgtc catacacagc agcttgcata
    26581 aatggataat agatcgtctg tctccaagct tctccgtttg tttctgtcct gattggtgca
    26641 ataacattta ccaattgagc aagacaagca atctttactc tatctgcatg tttcaataaa
    26701 gtgattaata gacagcctaa tagtaatgca tcttcaaaat tatagttatc ttctagtaaa
    26761 ggaggagcaa tctgccaagg cgctgcttgc tcatcttgtt ccgctgaatg ataccaaata
    26821 ttccattcat caaaggacag gttgatctgc ttcttactat gtttcttcgc cttgactgta
    26881 tcgcacatcg ctgtcacttc agaaatgaac cgatccatgt ctaaggaacg tgcaagataa
    26941 tgagaaagat catttttttg gttgccataa tattgatgca gagacaaata atctatttga
    27001 tcgtacgctt gatcaagaac tgttaactcc caatcaccaa atgtaggcat ttgccgattc
    27061 gaacttccgc ataaaaccac ctcaattgaa tcatctacga gtttcatcgc cttagccgtt
    27121 tcctctgcta accgtccata ttcttccgct gttttatgtc caatctgcca aggaccgtcc
    27181 atttcattcc ctaaacacca tgtcttaatt ccaaaagggc tctcttgacc attcgaacgc
    27241 cttaaatcac tccaataagt tcctttagga aaattacaat attcgactaa attacgagct
    27301 gcatctactc cacgagtacc cagattgaca gccatattga tttcggcccc cacatgctga
    27361 caccagttat aaaattcatg aatcccaact tcattcgttt caattgtccg ccaagctaaa
    27421 tccaaccttc taggtctatt tgctatgggc ccaatactgt cttcccaacg aaatcctgac
    27481 acaaaatttc caccaggata tctaatcatg ggaatgttca attcttttac caagtgaatg
    27541 acgtcttggc gaaatccact tttattagct gatggatgat ctggctgata aatcccttca
    27601 tatactgctc gtcccatatg ttcaataaat gaactgtaca accgcggatc aactttgcct
    27661 acacgcttga cactactaat caacattgtg gcttccataa ctgacctcct ttaatttata
    27721 catgaataat acacctcgtt gaaagcgttg tcaataatat aaatgttaaa cttacttatt
    27781 ttttatcgat tttaattaac caaaatatta ataatgatta aaacaaataa tttaatataa
    27841 cttttattaa caaatatgtt aatatataag aaaaaccttt taagaggtga tatatatgca
    27901 actacaaata aacgaagaat ccttaccggt atatgaagca ttagctagta aaacaaggat
    27961 caagatcatc cagctacttt ccaaaaaaaa gatgaatgtc aaagatttgg caaaagaact
    28021 tggagtgagc agtgctatca cgacgatgca cgtgaaaaag ctagaggaag caaacatcat
    28081 caaaacagaa aaagtaggac aacaaaaaat ttcgagcctt cgtgtcgata aaatcgatat
    28141 cagttttcca gaaaaaatat tcaatgcttt tgatacgaaa gaaacatcga tacctattgg
    28201 tcactataca aattatgcaa ttgaaccaac atgcggttta gctacgatcc atgattttat
    28261 cgggaaagtg gatgaaccac gctattttat ggatcctcga aggatggatg cccgcattct
    28321 ctggtttacc agcggatttg tcgagtatca ggcacctaat tttttaaata cagaggatac
    28381 attggagatg ttggaagttt ctgtggaaat ttcttctgaa tttccttttt caaatgacaa
    28441 ttggccttca gatatcactt tcagcctaaa tggtgtggag ctaggaacat ggacgagccc
    28501 tggagatttt gctgatatcc gcggtaaata tacgcctgat tggtatccag ataatcttaa
    28561 tcaatacggc ttgctgaaga cgatccgaat taccaaacac ttgacgaata tgaatggaga
    28621 acccttgtca aacatcacga tcaacgacat ccctaaagag caagacactt ggcatttgcg
    28681 aatcgaagtg aaagacgatg ccaaacatgt ggggggctgt actttatttg gtaaaggatt
    28741 cggtaattac gatcaggata tcaaattaaa agtttactac agctgatatt tttcttttct
    28801 attttataaa acaaaaacag ccaatcccta tgaagggacg gctgtttttg ctttattgtt
    28861 atttccagaa atcatccaaa acggaaattg gcaaatgtcg tttatgttgt gtcttgttcc
    28921 accatgcttc gattttttct tgtgcttgag cgggaacttc ttttccttct agataatcat
    28981 caatttcatt atatgtgaca cctagtgcga cttcatctgc aatcattggt ttcccatctt
    29041 caagatctgc agtcggaatt tttgtgtata atttttccgg tgcattcaat gcttgaagca
    29101 attgtttccc ttgtcgtttg tccaaacgga ataatggcaa aatgtcggct ccaccatcac
    29161 caaatttcgt gaagaatcca gtaatgtttt ctgcagcatg atctgtccct aatacggctc
    29221 ctgctctttc tccagctacg gcatattgcg taatcatacg ttgacgtgct ttgatatttc
    29281 ctttgttaaa atcgctgatt cccacacctg cttcgcttaa tacttgtact tgtgcatcaa
    29341 cagctggttt gatatttact cgcagactaa catcgggctg gataaagtca agagcagctt
    29401 ttgcatcttc ttcatctgct tgttcaccat aaggaagacg aacagcgata aattgatagt
    29461 tttcatcttt tgtttcttca cgcatttctt ccatcgttag ttgcgccaaa cggcctgcta
    29521 aagtagaatc ttggccgccg ctgataccta gtacaaaagt tttaagaaac ggatattttt
    29581 tcaaatatgc tttcataaag tcaatacttt tacgtatttc ttcttttgga tcaattgttg
    29641 gtttgacacc taattcattg ataatttctg tctgcaggct catttattct cctcctatgc
    29701 ttctgtatga agttctgcta cgcttttttt cattcgttcc atgatagcca ttttatggtt
    29761 ccagcattca gtagacagat cgactgggta tttttgcgga ttcaagtctc gtttatactc
    29821 ttcccatagt gaatctagat tttcttttgt atattctttg atttcgttta gtgcaggtaa
    29881 ttcgtaaact ctttttcctt cgataaagat atcttgtaaa actgggcgag ctgtaaagtc
    29941 tcgaacagtt ttattgataa acgtatgcac tggatggaac atgaagatag cttcttcttc
    30001 tcgagggtct tcatcccata atgtcacgta gtctccttca gatttcccat caaaatttcg
    30061 agtgatgcgc cacacttgtt ttttccctgg agtagttact ttttctgcat tgcttgataa
    30121 cttgatcgta tccatcattt ttccttcatc atcttcgatc gatactagct tgaatactgc
    30181 accaagggct ggctgatcat aggctgtgat caattttgtc ccaacacccc atacatcaat
    30241 tttagctttt tgcatcttta aattcaaaat cgttgcttca tccaagtcat tcgaagcata
    30301 gatttttgct tccgtaaatc cggctgcatc taattgttcc cgaacacgct tagatatata
    30361 ggccatatct ccactgtcga tgcgtacgcc ttggaagttg attttgtcac ctaattcttt
    30421 cgccacgcga atcgcacttg gcacacctga tttcaacgta tcataagtgt cgactaagaa
    30481 cacgcagtct ttatgggttt tagcgtaggc cataaatgct tcataatcat ttccataaga
    30541 ttggactaac gaatgagcat gggtcccgct agctggtatc ccaaatatct tcccagcacg
    30601 tacattgctt gttgcatctg ctccgccgat atatgccgct ctagttcccc agactgctgc
    30661 atccagttct tgtgcccgtc tagttccaaa ttccaatagt ggatcttctc cgatgacaga
    30721 tttgatacga gctgcttttg tcgcgatcaa cgtttggaaa ttgaccatat tcaacagtgc
    30781 tgtttctact aattggcagt gcgctaaagg cccttccact tggattaatg gttcatttgc
    30841 aaaaactagt tctccttcac gagcagaacg aactgttgct ttaaattcaa aattttgtaa
    30901 atactccaaa aaaccttcag gatagacttc taatccacgc aagtaagcaa tatcggaatc
    30961 attgaacgtc agattctcta aataattgac taaccgttcc aatcctgcaa aaaccgcgta
    31021 tccgtggtta aaaggcattt ctcgaaagta acattcaaaa acagcatgta aatcagctcg
    31081 acctaattcc cagtatgtct gcatcatatt gatttgatat agatccgtat gcagcgtcaa
    31141 actgtcgtct gggtaagtat tattcatctt gtattactcc tcttggcaag ttttcatttc
    31201 ctacccatta taacaaaaaa aattaatagg aaaagaaatc ttccattttt tctgaaaaag
    31261 cacatgtttt acggatattt cttgctaaaa atgaactcca tctgctaaaa ctatcctttc
    31321 ttattggtat ttaacctaaa cgagaaagaa tacttatttt attcaatgta tccgagacac
    31381 gaagaaatta gcgttttcta tttttcttac ttgataaaat aagtagattt tcctactaca
    31441 atcgtagccg ttaagatacc gatgattgaa caaatataac caaatgtctc tacaacataa
    31501 tcaatggcaa aagtttttga agcaataata cgtctttcct tttttgcttc ttatccccaa
    31561 agaaacggat ataacttatt atgtattgaa tttttttgga aaggcgaatt atgacaagat
    31621 ataccttgcg ttgaaaaaac tcgcggaaaa aatatcacac gtttttaaaa agatacaaag
    31681 taagaaagca gctgtcaata gaatggaaac aaaaatggcg agacatcaat cagtctcgcc
    31741 ttgtttttta ttgtatacat tagatatgga gcaggttacc ataaagatga ttattagtcg
    31801 ttattaaata gaatccttcg tatttttttg ttctatcact acaatatctt tatttggacg
    31861 tttgaattgt attccggcac gttctagctc ctgtttcact cctacatgga ctttgacatc
    31921 ttctcgtgtc atttttaaaa cgtgatgaat cgcatagtcg atttcttgcc ttgtgatttt
    31981 tttcttcgta ttgatcatca cgacttgctt tttatcatat gtgtctacca atagcagttg
    32041 tgttcgatct aacgaaaata atttgtaata attaatagcc gtattcccaa aaaagaattc
    32101 cactacttta ggataaaatg tcttaatatt taaattacta ttcacaggtg tttcgattag
    32161 cttcatctca ttcctctttt ctatatagtc gatttagatc caatcttaag ttatgttacc
    32221 atctttccta gcattaagga atcggttaca attgaacctt taaagacaaa aggatttacc
    32281 ttttatcact taatagtata acataatttc gtgagaaaaa aatacaattt tttcttgacc
    32341 atctcgttac gtaaaggatt atgcttacat ttgtcaggag gaaaaataat ggagtacaca
    32401 ataaagaaaa tgtcagagat atcaggagtc agtccgagaa ccttgcgctt ttatgatgag
    32461 attggactgc taaaaccagc taggatcaat tcttcaggtt atcggattta tggcaaaaaa
    32521 gaagtcgatc gtctgcaaca catcttattt tatcgaacaa tggcattcaa gttggatgat
    32581 atccaagagg tcttagacaa tccatctttt gaccaccaga aagctttaat caagcatcag
    32641 caaatgttgc tggaaaaacg ggcacaaatc gataccctct tgacaactgt ccaacagaca
    32701 cttgatatgt acgaaggagg aagaaaaatg agtgacaaag aaaaatttga agggtttaaa
    32761 caacaaaagt tgaaagaaaa tgaagaatcc tatggacaag agattcgaca aaaatacgga
    32821 aaaaaaaagg ttacagcatc caatgaaaaa tggatgaata tggataaaga aacgtatgaa
    32881 gaaatgcaaa ctgttgaaaa gcagatgtta tttgatctca ctctttactt aaaagaacca
    32941 gaagatgaaa gcttagcaga ccgtatcttc caagctcata agaagtggtt ctcttacagc
    33001 tggcctgaat atcagccaaa agcgcataaa ggactaggaa tgatgtacga agccgatgaa
    33061 cggttcactg catattatga cgagcgaagt ggtcatggtg cagcaaaagc tttaaatgaa
    33121 attatccaaa aaaaggcgta atcttttaca tgatccaaca aaaaagtaca cgtaaaatga
    33181 cctaataaca aaacagcaga cacccaagtt agatttttat gctaactttt ggtgtctgct
    33241 ccattctttc acaagttttt tcatcctact ttaaatatat tcatcgttga ataaacgtat
    33301 aaggtatttt cactttatcc tttttttctg taagaaacaa ttgaaatgcc atttctccgc
    33361 aagcttccag atggtggtcg atggttggga aaccaagaag ctcgctgatc agcaaattat
    33421 cccgtccaat caccactggt gtcttatctt gcagatagct ttgcaagatg cctgctgcaa
    33481 ccatatccga atttgtaaag acaccatcaa ctccaagctc tttaaaaaag aagcctgctt
    33541 gttttccttt ctctgcatct atacaatccc aaaaaacaag tgattcatca aaagatggaa
    33601 aaagttgatg acatagctgc aaagtgattt ttgagttata acttagcctg ccacttcgcc
    33661 ccaacgtgat gcccaattgc tttatacctt gctgcttcaa ataagtaaga ccttctgtaa
    33721 ttgattgttc tcgatcaata aagacacagc ttgcctgttt tcccttgatt tcttcacaaa
    33781 aaactagagg tccatatttt tgatatgcca ataaatcatc tagtgtattg gcacgagacg
    33841 taatgatcaa tccatcgaaa gctttagctg caaattcttc aagatacctt cgctcttttt
    33901 ctttatgata gcccgtcggt aaaagtgtca ctttgtaatc ataatcaaac gctgcttcaa
    33961 tgatcccact gatcaactga tcaaaatacg gatgattggt ataaggcaga atcactccaa
    34021 tgcttttcgt ttttccataa cttaactgtc tggcatttgc attagggata taatcgactt
    34081 ctttcatgac cgcaagtatt tctttccttt tttcctcatc tacatatgga tgtccattga
    34141 ttacacgtga aatagtagaa actgaataac ctgtgagctt tgcgatatct cgaatgtttg
    34201 ccactgctgc ttcgccacct atacaaaaag attttcttgt aaatagtcta ccacagctgg
    34261 accgcattca aaaaactgat acatttttcc ttcatgcgaa aaactgatcc gctgcccgcc
    34321 ccaatatata tcttttgtca aattttcgat ttcattcatt ggtatttctt ttactatatt
    34381 cctattcaac ccttgaaaac tgtacaacgt taatacggat cccttgaact cgacaaacgc
    34441 ataaaaataa ttgttcgttg tgccatctgt tatctctaca taagtattca ttgcaagccc
    34501 tccttttgat actttgagta tagtgtatga aacgcgtctc atagcaagga gtttgttttg
    34561 ccaaagaaaa gttttattcc tctttcatta ttaccaaagt ctcttatttt aaattgaata
    34621 cattataatg atactgtaaa tatatcttta ttattagtga at
//
LOCUS       DAIGWC010000024        34654 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.024, whole genome shotgun sequence.
ACCESSION   DAIGWC010000024 DAIGWC010000000
VERSION     DAIGWC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.024"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(60..1613)
                     /locus_tag="NOB74_001161"
     CDS             complement(60..1613)
                     /locus_tag="NOB74_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1220361.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            1761..3050
                     /locus_tag="NOB74_001162"
     CDS             1761..3050
                     /locus_tag="NOB74_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI1220362.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEVAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(3176..4255)
                     /locus_tag="NOB74_001163"
     CDS             complement(3176..4255)
                     /locus_tag="NOB74_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI1220363.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(4364..4804)
                     /locus_tag="NOB74_001164"
     CDS             complement(4364..4804)
                     /locus_tag="NOB74_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1220364.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(4861..5271)
                     /locus_tag="NOB74_001165"
     CDS             complement(4861..5271)
                     /locus_tag="NOB74_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI1220365.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(5452..5886)
                     /locus_tag="NOB74_001166"
     CDS             complement(5452..5886)
                     /locus_tag="NOB74_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI1220366.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(5986..6834)
                     /locus_tag="NOB74_001167"
     CDS             complement(5986..6834)
                     /locus_tag="NOB74_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1220367.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            7223..8989
                     /locus_tag="NOB74_001168"
     CDS             7223..8989
                     /locus_tag="NOB74_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HCI1220368.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            9091..10350
                     /locus_tag="NOB74_001169"
     CDS             9091..10350
                     /locus_tag="NOB74_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI1220369.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            10497..11798
                     /locus_tag="NOB74_001170"
     CDS             10497..11798
                     /locus_tag="NOB74_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1220370.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            11801..12652
                     /locus_tag="NOB74_001171"
     CDS             11801..12652
                     /locus_tag="NOB74_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1220371.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            12665..13480
                     /locus_tag="NOB74_001172"
     CDS             12665..13480
                     /locus_tag="NOB74_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HCI1220372.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            13631..14797
                     /locus_tag="NOB74_001173"
     CDS             13631..14797
                     /locus_tag="NOB74_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1220373.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            15027..15674
                     /locus_tag="NOB74_001174"
     CDS             15027..15674
                     /locus_tag="NOB74_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCI1220374.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            15758..16702
                     /locus_tag="NOB74_001175"
     CDS             15758..16702
                     /locus_tag="NOB74_001175"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HCI1220375.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            16837..18288
                     /locus_tag="NOB74_001176"
     CDS             16837..18288
                     /locus_tag="NOB74_001176"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HCI1220376.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            18309..19145
                     /locus_tag="NOB74_001177"
     CDS             18309..19145
                     /locus_tag="NOB74_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCI1220377.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            19145..19804
                     /locus_tag="NOB74_001178"
     CDS             19145..19804
                     /locus_tag="NOB74_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI1220378.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            19930..20619
                     /locus_tag="NOB74_001179"
     CDS             19930..20619
                     /locus_tag="NOB74_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220379.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            20625..21581
                     /locus_tag="NOB74_001180"
     CDS             20625..21581
                     /locus_tag="NOB74_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HCI1220380.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            21625..22137
                     /locus_tag="NOB74_001181"
     CDS             21625..22137
                     /locus_tag="NOB74_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1220381.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(22393..22941)
                     /locus_tag="NOB74_001182"
     CDS             complement(22393..22941)
                     /locus_tag="NOB74_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1220382.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(23030..24211)
                     /locus_tag="NOB74_001183"
     CDS             complement(23030..24211)
                     /locus_tag="NOB74_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HCI1220383.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(24447..25955)
                     /locus_tag="NOB74_001184"
     CDS             complement(24447..25955)
                     /locus_tag="NOB74_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HCI1220384.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            26114..26305
                     /locus_tag="NOB74_001185"
     CDS             26114..26305
                     /locus_tag="NOB74_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220385.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            26508..27425
                     /locus_tag="NOB74_001186"
     CDS             26508..27425
                     /locus_tag="NOB74_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HCI1220386.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            27418..28491
                     /locus_tag="NOB74_001187"
     CDS             27418..28491
                     /locus_tag="NOB74_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220387.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            28639..29157
                     /locus_tag="NOB74_001188"
     CDS             28639..29157
                     /locus_tag="NOB74_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220388.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            29138..29530
                     /locus_tag="NOB74_001189"
     CDS             29138..29530
                     /locus_tag="NOB74_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HCI1220389.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            29606..30541
                     /locus_tag="NOB74_001190"
     CDS             29606..30541
                     /locus_tag="NOB74_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HCI1220390.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            30674..31453
                     /locus_tag="NOB74_001191"
     CDS             30674..31453
                     /locus_tag="NOB74_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI1220391.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            31446..31763
                     /locus_tag="NOB74_001192"
     CDS             31446..31763
                     /locus_tag="NOB74_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI1220392.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            32007..33617
                     /locus_tag="NOB74_001193"
     CDS             32007..33617
                     /locus_tag="NOB74_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI1220393.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            33774..34622
                     /locus_tag="NOB74_001194"
     CDS             33774..34622
                     /locus_tag="NOB74_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI1220394.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        11456 a         6166 c         6707 g        10325 t
ORIGIN      
        1 cttgatacat aaatccggag gttgttaata agcattcgga tttatgtatc ttatttggtc
       61 taggaagtaa cttgattttc ttttttcgat tgatccatga gtgcttcttc ttttaattca
      121 aagatatatt ctgagatcct cataatcact tttttccagt cttctggtgt gatgattcct
      181 tttaaaatat agattttttt gatatgagaa ggcaattgtt tcaaagggca gtcgctgata
      241 acgatgttgc agttctccat aaaatcattt tgtattttga tcgattcatt tgaaaaaatt
      301 tgttctatct taacgatcag atctttactg atataaaaat cacgcgtata gttcacacca
      361 atcacaattc gcggctgttt tttgtagcga tcatacaaat gtactaggtc ttcaaccatc
      421 cattgcacat tttccttttc taaaataact ggtaacaagt gttgattttg ttctctgaaa
      481 tccatataaa attgttcaat ggcggtttgg acttctttca acacgctatg ttcttgataa
      541 agcatgaaag taggaagggg cgtatttggt tgattgaagt taagaaatcc attataaagt
      601 ttatttcgtg cgaatgccaa tgagtaaaga atcttttctt tttcaggtat aaacaaatca
      661 aatacagtac aaaaggactc caccatttct cttgaataaa gaacatgagg aacgtttgct
      721 ttttttaaaa gtttgtattg ctccaagctt gtttcttccg attcgatttt cgtgatagaa
      781 agtcgagcta aaatattcac taagatgcgt tgttcgcgac aaattggcag attaggtcgc
      841 aaaatatcta cagagggatc aataaaaaag tcaatatatt catactctgt gaattctttt
      901 tgtacgtctt tcacagaagt tgcaggaaaa ttctctttac atatttttaa tagaaaatat
      961 aatttatcta tcataccgct atttagtcgg tcaagtactt cttttttaaa aaaagtattc
     1021 atcataaaag ccactacttg cggatcttca tcataaaatt ctgtagcagt acttgaaaag
     1081 atgttccaat aaatatctaa tgctgcatat tgaatttgta cctcttttcc agaaaaagac
     1141 tttctgccat tattagaaaa ggagatagac aaaccgtaca atgctaaaaa tgcattaatc
     1201 tttttcattt tcgtatacaa ataagaggca ctatagtttg tttgctgact taaactgata
     1261 atcgaatttg tctgacagct gaacaaagaa gtcaagatct gataactgac tgattcgttg
     1321 cagtatcttc caaatagacg ataatagcag taagccggat caattccttc aaaattcaac
     1381 tttaaaaaag gtttttgctt atcaatatgc agttctgtta gattgagacg ctcaaagtct
     1441 tgttctaatt ctttgatgta tagtaaaaaa tttgattcag acatatggaa atgatctgct
     1501 aaatattgtg tagtaataaa gaaacgatgt tcagatagga aaagaaaaat atctaatttt
     1561 gtattgcttt ttttcttcaa gagaaacgtt ttaatcgctt cttgagtttg catgaaagag
     1621 gctccttttt acttaaattg ttaaaacttg aaaatattac tgtttttttc ataaatttag
     1681 acaaaaaaac agtaaacata taggtagaat ctctactatc ttatttcttg catacaaaaa
     1741 aatcaaggag tgagagagtt atgagatatt caaccatctt aatatcaaca tttgcagcct
     1801 taagcttatc gcttactata aatcagacag tccacacaga ggagatagaa acagccaaat
     1861 ggacagaaac caagtgggcc aacgtcaatc gaattacctt tcaggatgaa ttttcatcct
     1921 tcaattcagg agtcgcaaaa ttaagaaaag gacaaacagc gaccatcaaa gcaaaaattg
     1981 actattcagg agacttagca cctatactac aatcagctgt tacatttgag aatgttgatc
     2041 ccgctttgtc gattggctat gacgagaaca ctttgactat ccaacacaag caagcgatat
     2101 ttaccttcac cgttacatta aatcaggact tgttaaaacc agcgcttttt actgtcaagg
     2161 tatcagatgg actaccgaac gatcatcatc atttaacgcc gtatagtcag cggcagacaa
     2221 ttgagcaaga ttcagctatc gactcaggag gagatcttgt tgaagaacca acagataaac
     2281 cagaaaatga aaataagcca gaagtaccgc ctacagaaaa tccagacgga gaacagaaac
     2341 cggaaataga acctggagaa gaacccgata cagaaactca accagagcca gacaatgaat
     2401 caaaacctga aataacccct ggagaaaaac cagatgtaga cccagaagaa aaaccggatg
     2461 tgactccaga accagatacg gattctggaa accaaacagt accggaaaca aatccagaca
     2521 cagataatga aactgaaaat ccagaaaaac cagaggtagc cccagaagaa aaaccagatg
     2581 taactccaga accagatacg gattctggaa accaaacagt accggaaaca aatccagaca
     2641 cagataatga aactgaaaat ccagaaaaac tagaggtaga tccagaagaa aaaccagatg
     2701 tgactccaga accagatacg gacgcaagag accaaggaat accagaaaaa ataaacaaaa
     2761 aaacaattca agaggatgga aaaaaagaga gtaaaaaatc aaatctagca attctaaaaa
     2821 taaatgaaga gcagctgaat aaaaaatcac gaatatttga tagcgcccaa tcagctgaaa
     2881 ccttaaaaag tagcaaggat acaacctttg ctagtcctga aacgaaaaat aaacagctac
     2941 caaaatccgg agagtcacaa aacaaagtta tactgtggag cggaatcatt ctattaagta
     3001 tagcaacaat gctttctgca aaaagattta aacaaaacag atctctctaa catttgaata
     3061 atgtctgtga acgcattttt caaataaaaa gaaatatcca gaaaacgacc ccaaaatacc
     3121 agattgaaat ctgatatttg gggtcgttca tactttatct ttcttcatat ttattttaag
     3181 ggatatctgt ttcttttgga agatggttcg ggatcttttt cactttcaat acatctaaaa
     3241 agaaggtaaa gatcggaatg ccgacaatca agccccaaac gccaaagaac cgttcgctaa
     3301 caagtaagac cacaaatgta taaaaaatcg gcagttctgt tttgctggac atcaacttcg
     3361 gattcagcac ataagactca attagatgga caatcaaaat cgtaatcagg atataaacaa
     3421 catctcggat gcctccttgg gaataagcta tgaaagatag aggaatacaa gaaatgataa
     3481 cacctgctac tgggatcaga cttaaaatga aaatcatgat cgctaaactc agcagctgat
     3541 gaaagccaaa tacagccaag gcgattgtag tgagcaacgt gtttaaaaga gcgataacaa
     3601 attgagcttc taataccaaa ccaaatgtat tgacaaactt atcggcaaaa tagtaaatat
     3661 cttgaaagaa ccaagaaaat tcacttttta aaaacaatct tgagaataca attgtttttt
     3721 tcttttcaat cataaaaaag aaacttaaga tgaatgacat agcaaacgcc actgccattt
     3781 ttcctatatc ctgtaaatag ccaagcgcaa tcgaagcgcc attttgaagc tgttcaaaaa
     3841 aatcgtttcg ctcaatataa gtatggatat attgtaaaac aggatctgca tcttttggct
     3901 gatgctcgta aaaatcaata acggactgga tcatatcaaa tgtttgatga ataagcatcg
     3961 ggatatactt tgtgaatgcc agatagataa ggtaaacgat cagtgtataa atcatgatag
     4021 ctaaaacacc tgtagggatt cggacaaatc gctgaatgat ttgaacaaga tgaatcatca
     4081 aataagtaaa gataaatgtg agcaaaatgg ttgtaatcat acttctaact aagaaaagaa
     4141 caaaaacgac aaataataaa acagtgagac ggcgtatttt ttcattcgcc aaaaaacgct
     4201 gataaacggt caaatcgaca acctccaaat aacaaaaaat aaacacgtta ttcattatat
     4261 gatggaatat gaaaataaga aagagaaaga gcaaaaagaa aaaccgctaa atgacgttat
     4321 cttatgagtt ggttttcctc ataaaatcgt tcatctagca gtttcagccc tttttctggt
     4381 cttgatgaaa attatctagc atttttcggg tcagatgttg cagtgtatcc aattcttcct
     4441 gttcaagtgg aagataagac ttgatctttt gtggaatacc ttctgcttgt ttttgcaacg
     4501 cagcaccttg aggagtcagc gtaacattta cgattctttc atcacccgtt tcacgctgac
     4561 gattaatata atttttttct gctaactttt ttagtaaggg agtcagcgta ccagaatcca
     4621 gacacaaatc atttcctagc tctttcactg aagtcttttt cttttcccat aaaactaaca
     4681 tcacaagata ctgggtatag gtaagattca gcggcttgag gagggaagtg tagtgtctaa
     4741 tgatttcctt agaggcggca tataaaggaa aacatacttg attaactaaa tatagatctt
     4801 ccatttttcc acctccgctg ttttactata gtgtatcata gcggatttac acaaaaaagt
     4861 ctattcacta actgctttca gagtaacttc tatatttcca gctgtagctt ttgaatacgg
     4921 acacacttta tgcgctgcct ctaataattc ttgcgtttct tccagagaaa gaccttcgat
     4981 agatccttca atctctacac ctaagacaaa gctcgtttca ctttctgaat aaagggaaac
     5041 ttgtgcactg acagtagaag ccccagagat atttttttgc tgtttgatca attctaatgc
     5101 actgttaaaa catgcactga aaccagctgc aaacaattgt tcagggttgg ttgcattttc
     5161 gacgcgttta ccaggagctg caatattcaa ttcgaatgta cgatcgggat tatgaacttc
     5221 tccagagcgt ccgcctgtgt tgatcatttt cgtagaatac atttttttca taaaattacc
     5281 acctttaatt atattttata caattgaatt ttacacaata taattgtgga aagcaaagaa
     5341 atggattggc ataagataaa taagagaaag cacatgaaac agacgcgctt tctcgaatag
     5401 caaacatata caaaaaaata tcagagacaa aaactaatct catcataaac attacatata
     5461 tttctcaaaa agttgttttc tttcttcaaa acttacttca cgatggacct gatgaagcat
     5521 ccataaataa ccaaaaggat ctctgaacat tgagttagtc acaccaaagt ccatcatttc
     5581 tgtcatttct tgaatctcta cacagccatt tcgtaatgct ttattatgtg tgtcctcgat
     5641 atcagagacg atgatattga accagatcgt atttggatgt tcagcagtag gagcagtcaa
     5701 accaagagac gtgttttcat ccagcatatg gaatctcgtg ccatacaagg taaaaatgac
     5761 ttcattattg cctctagggt aatctgttgc ctcaatcagt tgtatttcat caaagattgt
     5821 ttgatacagt tctagtgctt tcaaactatc atttaataca aaatctattt ccgttccttt
     5881 atgcataaag atctcctctc cttttcagtc gaacagttac tagattcttt tattatacca
     5941 gttaaagaaa acgcattcaa aaaaatagcg gatttactta ccaactcatt cgattggatg
     6001 ataagtaaat ccgcgtccca ttacttctgc tacgctgctg acaatgacaa aggcacttgg
     6061 atcgatttct tctatcaatg gtttcattcg ggaaaattca tgatcagtca caacgatcaa
     6121 taaaacctct tttgactttc gattataccc gccttttgcc tctagcaggg taaggccacg
     6181 tccaatctca gcacttaagc gaaggcggat gtcttccaaa taatgttcac tcatgaccat
     6241 aacagatttc tttcgattga tacctgtttc gatataagtc atgacaattg aagtgattgc
     6301 aatagataaa atagcataaa gaaactcttc tattccaaaa acaaacagat taagagaaac
     6361 aacgaatgcg tctgtaaaaa ataagccaat cgaagtattc aagtggaaat attttttaaa
     6421 aatgagggga gggatcgtcg taccgccgct agaagagttg tttttatata aaatcgcaac
     6481 tcctaaagca aaaatcgcac ttccaaaaat gacagacaac aaccgatctg aagtaatcat
     6541 tgtttctgga actattgcaa tgattaaagg aaaaaacaag cttccgaaaa gtactttaaa
     6601 aaagggtttt ttacctaaaa atagaagagc tagtaccaac ataacgatat tcaacactaa
     6661 aataactata gctcggtcaa atcctaaaac agcttccagt aatattccta gaccgctgac
     6721 acctccagca gcaatatgat gaggccctaa aaacatattg atagcgactc ctaatatgaa
     6781 gagggcaaaa ataatcttaa tgtatgtcca tataaattgt ctcgtttctt tcatttatcc
     6841 acttccttaa ttcattaata atactcttat cttattataa cttacttttc accttaagtt
     6901 aactttaatt aataaaaaaa ttaggctagt ctaaattatt atgtttcatt cttctagaat
     6961 atacttctac gttaaaaact gttaaaaaac ttttacttta gaaaattgga gaaattgatc
     7021 gcttaagata aattcaggac actaaatagt acaggaagta gattaaaact tttaaaagtt
     7081 ttaagtctat ctatttggca agtttaaaaa ataaaaattc ggtatcaaaa aactgttacc
     7141 gataacattt ttgaaagcgt tgtcttttgt ttctctatca cttatagtga tgacgtcata
     7201 ttaaaacaca aggaggaaat caatggatac agctgcaatt tatcatcgac cggaaagtga
     7261 atatgcattt ctatatacga atacaagatt tcgtattcgg cttcgtacta ggaaaaatga
     7321 tatcaaaaaa gtatatgtgc tttgtggaga tccatatacc ataacaactg aaaaatggta
     7381 tcaaaaacaa cgaccaatga aaaaatgtct aagtaccaat gttcatgatt attgggaaat
     7441 tgaagtgacg agcgaaacaa ggcgcttaca gtatgcgttc catgttgttg gggaagataa
     7501 cacggactgt ttttacggtg atcaaggaat ttttccttat cgagaaaatg tgattactga
     7561 accaaatttt tattttcgaa taccttattt tcatcaaatc gatcgattca ctattccaga
     7621 atgggtaaaa gaaacagtat ggtatcaaat ttttcccgaa agatttgcaa acggggacaa
     7681 agcaaatgac cccgaacaca ctttaccttg gggaagtaaa gatccagacc gagaagactt
     7741 cttcggggga gatttgcaag gtgtgaggga tcatttggat tacttgacgg accttggcgt
     7801 caatggcatc tatttttgtc ccatatttaa agccacatcc aatcataaat acgatacgat
     7861 tgattattat gaggtggatc ccgcttttgg cgataaaaaa cttttaaaaa acttgattga
     7921 tgaagcacat aaaagaggga tacgtatcat gttcgatgct gtattcaatc atatgggtgt
     7981 ccattcacca cagtggcaag acgttctcaa aaacggagaa aaatcgatct ataaagactg
     8041 gttccacatc cgttttttcc cagtagattc ttatcagatg actgacttac cagaaactgc
     8101 tgaaaatatc ccatatgata cttttgcttt tactccattc atgccgaaac taaatacagc
     8161 aaatccagaa gtgcaaaaat atttgctgga tatcgcaact tattggataa aagaattcga
     8221 tattgatgga tggcgtcttg atgttgctaa tgaagtcgat catcattttt ggaaaaaatt
     8281 cagagaagca gttacagaaa tcaaaccaga catctatatc cttggagaga tttggcattc
     8341 ctctcaagct tggctgcaag gggatgaatt ccatgcagtg atgaattatg cattcacaga
     8401 ttcgattaaa gattattttg caaaaaagaa aatcacagct tcacaaatgg tcagtggaat
     8461 gaatcatcag caaatgcttt acagagatca ggtgaacgaa ggaacattca acttattaga
     8521 ttctcatgat actgccagga tcttgaccct ttgccaaggt aacaaagaat tgatgaagtc
     8581 tgtgatggcc tttatgtttc ttcaaaaagg gtctccttgt atctattacg ggacagaaat
     8641 agggatgact ggtgaagatg acccggattg ccgcaaatgt atgatatggg agaaggagga
     8701 acaagatcta gagctattcg gttttataaa agaacttgtt tctctaagga aacagttgtc
     8761 taagattatt tctgaaggtt ctactcagtg gctaatagta tatgatcgtg aagataagct
     8821 ctatttcaca cgggaactag agggacagat catctatgtt tactttaatc agtcaaaaga
     8881 accttgggta gtagaacagg aaaatgaggt gattcttagt caaaattgtc agttgttaga
     8941 agacgggaaa gcagagatac gacaatacgg atttttgatc atgtgttgaa aactgttacc
     9001 ggtaacaaca agaaagcgtt tgcaaatgaa gatttgtgcc cattataata agggtgtaac
     9061 agcacgttga atacacagga ggaaatgaag atgaaaaaaa gaagtgtgaa acagttgggt
     9121 ttagggttaa tctctttagg aatcttaggc ggattagcgg cttgtggcaa tggtaactct
     9181 tcagcagaag gggaagccga tgaaggaaaa acgttaacag tttccgttga ttctggatat
     9241 aaagattata taaacgaaat aaaaaacact ttcgaaaaag aaaacgatgt gaaaatcaag
     9301 ctagtagaaa aggacatgtt cgatcagttg gaatcattag cgttagatgg gcctgctgga
     9361 aagggacctg acgttatgat ggcagcatat gaccggatcg gtgcgttagg acagcaagga
     9421 catctggcgg aagtaaaact gggaaatgaa gcagcttacg atgaaacaga caaagcccaa
     9481 gtgacttatg atggaaaaat ctacggagaa cctgcagtaa tcgagaccct tgttttgtac
     9541 tataacaaag atttagtcga tacagcacca tcaacgttta aagatttgga gaatctatcc
     9601 aaagacagtc gttttgcttt tgagtcagaa gcaggaaaaa atacaggatt tttagctaaa
     9661 tggactgact tttattattc ctatggttta attgcaggtt acggtggcta tgtatttggt
     9721 gatgatggca caaatccttc agatatcggt ttgaataatg caggtgctgt agaaggaatc
     9781 tcttatgcaa cagattggtt caaaaatgtt tggccaaagg gaatgcaaga cataaaaagt
     9841 gcaggagact tcgccagcca gcaattcatg tccaataaaa ctgcagcaat cattgacggt
     9901 ccatggcaag cgcaaacata caaagaaaac aatatcaatt atggtgtagc caaaattcct
     9961 actctaaata atggacagcc ttatcaaccg tttggcggag gaaaaggatg ggtagtcagc
    10021 aattatgcta aaaacaaaga cctctctcaa aaatggcttg attatgtaac gaatcaggaa
    10081 aatcaagaaa aattctttga aatggtaaat gaaatccctg caaaccaaca agctagggaa
    10141 acagcaaagg ctaaaaacga tgaattaaca acagctgtga ttgaacaata tgaaacagct
    10201 caagcgatgc caaacatccc agaaatgggc gaagtttgga caggtgcaga aaacttgatg
    10261 ttcgatgcag catcaggttc aaaaacacca aaagaatccg cagatgaagc agtaaaaaca
    10321 atcagtgaag ccatagaaca aaaatactga ttaaaatgat aaccgtccat ttttataaaa
    10381 aatggaacag gtgcttcaga taaaagtggc aagagcgaga tggaaaatta tcttgctctt
    10441 gttgccatta tcttaaaagc agtttgcggt ttagcaagtt tagagggggc attcagatgc
    10501 agcaagataa aacaagcaat atcaacgaaa aaaaaatcac gctttgttca cttattccag
    10561 ggatggggca gtttgtaaat ggccaagctt ttaaaggtat cgtttttttc gccatattcg
    10621 tcctattcat tggtcagatg cttctgggcg gatttcatgc attggtagga ttggttactt
    10681 tgggaagtat accaatggaa gatcattcat tatttatttt gattgaaggc actttgcaat
    10741 tcatcattac aatcattttc ttgatttttt acggtttgaa tcttttagac gcttatcgag
    10801 tagcgaagat gcgtcaagag ggcaaaaaaa tcaatcggac gatgaaggaa gtcatacata
    10861 atataggtga tgaaggtttt ccttatctat tgacacttcc cgcttatctt ctcatgattt
    10921 ttacgatcat tttcccagtc ctagttacat tgttcactgc atttactaat tatgacttca
    10981 atcatattcc accagccagt ttaattgatt gggtaggggc taaaaacttt tttagtatct
    11041 tctttttaag ctcatatcgt aatacttttt ttgcagtctt ttcgtggacc gtgatttgga
    11101 ctttatgtgc aacaactttg caaatcaccc ttggtattct cacagcggtt gttgctcacc
    11161 agaaatttat taaattcaaa cgtattttcg gtatcatttt cttattacca tgggcggtcc
    11221 cagcttttat tactatcatg agtttttcga atatattcaa cgatagcgta ggtgccatca
    11281 atactcaagt gattcctttc ataaaccagc ttccttttgt agatatcagt gcaatctctt
    11341 ggaaaacgga cccgaactgg acgaaagtag caattatctt agtgcagggc tggttaggat
    11401 ttccctatat ctatgtgatg gttacaggaa tcttacaatc gatttcagaa gacttatatg
    11461 aagcagcaaa aatcgacgga gcaaatgcat ggcagcgctt ttcaaacatc acgcttcctg
    11521 ctgtcttcct agtggcagcg ccaacattta ttacacagta tacggggaat ttcaataatt
    11581 tctccatgat ctatctgttt aacaatggtg gtcccggaag cgtaggcgga ggagctggtt
    11641 ctactgatat tcttatttcc tggatctata aacttacgac tggaacttct ccgcagtatt
    11701 ctatggcttc agcaatcacg ttgattatct ccgtcatcgt tatctgtgtg tcattgctgg
    11761 tatttaaaaa gacaaatgcg ttcaatatgg gggattaaca atgaaaaaat ttcattcgag
    11821 tgctcgattc caaaaacgac tttctcactt ttttacttac ttttttcttt taatactgtc
    11881 agtcattatc atctatccgc ttttgatcac agcaagtact gccttcaagt caggaaatat
    11941 tgcagctttt agtttagatc tttcaagtga ctggacttta ggaaacttta ctcggctatt
    12001 cagtgaaaca ctttacggga cttggtataa aaatacattg atcatttctg tcctaacaat
    12061 gatcgtacaa gtgactgtag taactttggc gggctatact tatagtcgct atcgttttat
    12121 cggccgcaaa tcaagtttga tgttcttttt agtgattcag atggtaccga ctatggcagc
    12181 attgactgcc ttttatgtca tggctttctt attagaagcg ctcgataagt actggttctt
    12241 gacaatgatc tatataggcg gtggaattcc aatgaatact tggctgatga aaggatactt
    12301 tgacactgta ccaatagatt tagatgaatc tgctaaactt gatggggcag ggcatttcag
    12361 gatttttttc cagattgtat taccgcttgt caaaccgatg ctcgccgttc aagcattatg
    12421 ggcttttatg ggaccttttg gggatttcat gttagctaag ttcctgcttc gaacacctga
    12481 aaatcagact gttgctgtcg gcttacaaac atttatttct gatgtgacaa accaaagagt
    12541 ctctcttttt gctgctgggg caattttgat tgcactaccg atttgtctat tattcttctt
    12601 tttacaaaag aactttgtta ccggcctgac atctggcgga acaaaaggat aggagcagag
    12661 tatcatgcaa acatttccgt taaactattt ttccgcatta cgtacgccaa ctcaagtgtt
    12721 tgcgggacgc aaactattat catggcctaa atttttcttg atatttgtat ttttagtttc
    12781 cttgatggtc atgcctgtga ctctttttta tgccaatcag atccaagcga ttccattaga
    12841 acaatttcta tccgttcatt cgctgatcga tgaacaagga acccaaaaat tttctgaact
    12901 tgaattatct gaaactgggt tacaagcatc gcaacaaacg atagctgtga cccctgaaat
    12961 tttggtaggt gtgtctttat ctgagaaaca acaatccgat catggaactt ttattgattt
    13021 tgagaaggaa caatgggtga tccaacaaaa ggataaatct ggtatacgcc gctatacgat
    13081 gaattatagc ccatctttcc aaccagattc tgtacgtacg cccgaagatt tccaacgatt
    13141 tttagaaaga gaattttatg ccagtaatcg tccaacaatc attttatctt atagtttaag
    13201 tcttggtctt gtcctatttg tcatgacgag tctcatttta ttcggggctt cctttttctt
    13261 gtggatgaca agaaaaagcc aactttcatc cattcataca ttcaaagaga gtgcaaattt
    13321 gatgctgaat gttatgggaa taggttccat ggcagcagca gttgtagggt ttatccactt
    13381 tgactttatc ttgatgctaa gtgtccaaac aacgataact gtcttgctgc ttttatgggt
    13441 ttttgtcaaa acaagattca aagataagcg tgtcgaatga caagtttaag cgatttatgc
    13501 gacaatgaat gtgaaaaaaa tgaaaaataa agtagttttt gaaaaatttc tgaaaaaatt
    13561 aaacttctta gttgattctt ttctttttta gtattaacgt aatagggtag tttttttaag
    13621 gaggaaaatc atgttagaga aaactttata caatcaatta ttttcacgtt ctttctcgct
    13681 ccctgtcgaa gtaaattatt gggacggtac aacgaaacaa tacggagata cggacactcc
    13741 tccccaaatc aaaatcaata tccatgaaga aatcccaatg aaagagatta caagtaacgc
    13801 ttctttggca ctaggagaag cctatatgga tcatcgaatc gagatcgagg gaagtatcca
    13861 agcattgatc aacgatgctt atcagcaagc aaacagcttt ttacgaggaa aagattatct
    13921 aaaatggctg ccaaagaaag aaaaacatac gaaacaaaaa aacaaagaag atatccatgc
    13981 gcattatgac ttaggtaacg acttttataa actttggcta gatccaactt tgacttattc
    14041 ttgtgcttat ttcaatacac ctgaagatac gttggaacaa gcacaaatca ataaagtcca
    14101 tcatatctta gacaaactct ttatcaaaga aggcgaaacg ttgcttgata tcggttgtgg
    14161 ctggggaaca ttgatgttca ctgctaccaa agagtataat gtcaaggcaa ctgggatcac
    14221 actaagtgaa gaacaatacg atttgattac caaaagaata aaagaagaac atttagaaga
    14281 taaatgccgt gtattattaa tggattaccg cgaactaaaa ggcgaaacgt ttgatcatat
    14341 cacaagtgta ggtatgttcg aacatgtagg ttctgaaaat cttgaaggtt atttcaaagt
    14401 ggtaaaagat ttattgaaac caaaaggaac agctttgatc catggaatca gccgacaaca
    14461 aggcggtgcg acaaatgctt ggatcaataa atatattttc cctggcggtt atgtccctgg
    14521 tgttactgaa ttagttgata atattacaaa aaacgatttg caactgattg atttggaaag
    14581 cttacgtcgt gactaccaat tgacattaga acattggaca aagaattttc atcaagtcca
    14641 agatcaagtc acgaaagaaa tgggtgattc cttctatcga atgtgggatc tatatttaca
    14701 agcttgtgca gcttcatttg aatcaagtaa tatcgatgtg attcaatatt tgcttgttca
    14761 acctggaaac aatgacatcc caatgcatcg tgcataattg aggcaaaagt actgtttaaa
    14821 gactatttaa aaagaagcta agttttatga tgctccagaa gtgaactttt ttgtctaact
    14881 tctaggattg tctctaaagc ttagtttctt tttctttata ttttcataat aaaagtttgg
    14941 ttctttaatt tttaaacatg acagaaaatt ttttcttcgt tatacttgta atagaatact
    15001 attttataac aaaggggatc gaatcaatga aaaaaactgt tatttatact agtttatttg
    15061 cagctttgtt tttagctgct tgtcaatcaa ataccaatca aggcacatct gggaatacgt
    15121 cttccagtag cgaacagcgc tcttcacagg tatcggactc ctcaacaaaa gcaagcacat
    15181 cttcgtctag ccagacaaaa agttctagtg aagcaagtac tcagtcagat atcaaagtgt
    15241 ctgcagctcg tgcgatcgaa ttgttccaag ataaataccc agatactgca attactagtt
    15301 tggaattaga tagtgattgg ggatcttact tctacaagat agaaggtgtc gatgatcaaa
    15361 aagaatacga agcaagaatt gatgctcaaa atgaaaaaat ggagacagag aatccagaaa
    15421 ctctagatcg agatgaacaa aatggtcaaa agaaaaaaga agatggtctg gatgttgata
    15481 aattgatcac gattgaggaa gcagcaaaaa tcgccgtcga caaagtagga agcggtacgg
    15541 caacagattg ggatttggat aaagatttag gtactactta ttgggaagtc aaagtaaaag
    15601 acggcaatca aagtacatca gtcaagatca atagccaaac aggcgaagta ctgtcaactg
    15661 aacaagatga ttaagaattt cttcggaaaa caagagttga tttttctttt agtcatgata
    15721 cactagacaa aataacttgt ttgaaggagc gatttacttg agtttagaaa cgacctttgc
    15781 caatcatatc tttgccaatc ctttgatgaa tgcatctggt gtccactgca tgactaccca
    15841 ggaattagat gaactggctc attcagaagc aggagcattt atcactaaga gctgtacgat
    15901 caatgaacga aaaggaaatc ccgaaccacg ctattttgat gttcctttag ggagtatcaa
    15961 ttctatggga cttccaaact taggtttttc ttattatcta gagtatgctc ttgcgtatga
    16021 aaaagtgcag gaaaaccaaa atcaaccgtt atttttttcc attgccggga tgagtgtcca
    16081 ggaaaacttg gaaatgcttg agaaaataga aaaaagtggg tttaatggga tcactgaatt
    16141 aaatttatct tgtcccaatg tgcctggaaa accacaacta gcttacgatt ttgaggccac
    16201 ttatgaaaca ctgaaagaag tattcagcat cttttctaag ccgctaggaa tcaaattgcc
    16261 tccttatttt gattttgctc attttgatca gatggctgat atcttgaatc agtttccatt
    16321 gacctatgtc aatgctatca acagtgtggg caatggtttg tatatcgata cagaacaaga
    16381 agcagtagtc atcaaaccaa aagaagggtt cggcggcatt ggcggagagt atatcaagcc
    16441 gactgctttg gcgaatgttc gcgcttttta tacacgtttg aaaccagaaa tccaaatcat
    16501 tggtacaggt gggattcgga caggacaaga tgcatttgaa catctgctat gtggcgcaag
    16561 catgttacag attggtacag agcttcataa agaagggccg gaaatttttt ctagaatcat
    16621 aaaagaatta acgcagatta tgtcagaaaa aggatatacg tcaattgacg aatttaaagg
    16681 caaattacgc accatttcat agcaaagaga cgaaggtcat gattgatctt cgtctttttt
    16741 tataaaaaac actcgtctgt tcattcctgt gcaagcgtac tcattgtatg ttagacgaac
    16801 ttgtgggaaa ataacagagg caaaaaggag gataatatga atgatgcaac agaattagca
    16861 aaagagctta aagaaaaaga atttagtttt caagaactag ttacggatat acagaaaaaa
    16921 ataaagaagc aaaatcatga attgaatgcg tttgtcgcgc ttgaaccatt cgagagtaat
    16981 tcccacgagc tattgattcc ccagtcagaa aaagggccat tggctggtat cccatttcct
    17041 ttaaaaatgc tcggtcaaga aaaaaaggga tggctagcta cttcaggatc tcgtttattt
    17101 gaaacacacc gagcttctca tacatctaat tatgtgcggc aagcagaagc gataggtcta
    17161 gttccttttg gacaaaccaa tgcgccagag tttggtttca aaaatattac agacccagtc
    17221 atctatggcc cagcaagaaa cccttggaac cttgaatgta caccgggcgg atcaagtgga
    17281 ggagctgctg ctgcagtttc atcaggaatc gttcctttag ctggtgctag tgatggcggt
    17341 ggttctatta gaatacccgc ttcgttttgc ggattgattg ggctgaaacc ttcgcgaggg
    17401 acgatgccag ttggtccata tgcttggaga ggatggcaag gagctgctat tgatttcggc
    17461 ttgacagttt ctatgagaga cacggaggct ttattttatg ggatgagaag tatccattcc
    17521 ggtgcgccat atcaagtatc gccagttgag tggcaaacac atccaagaaa aaaacggttg
    17581 aagatagctt tttgtgttga ttcaccgatc cactcacaga ttagtgaaga ggcagtactt
    17641 gctgtaaaaa aagctgtaga tttccttgga aaagaagggc atgatttgac agagattcct
    17701 tacccactag atggtcgtaa actgatcacg tcttattatc agatgaatgg cgcagaaaca
    17761 gcagcaatga tccgctcgat tgaaacaggc atccagcgag ctgtcagaaa agaagaactt
    17821 gaacccattt cttggacttt gttccaatat ggtcagaagc tctctgccgc tacttacatc
    17881 gattctctgc atgtatggga tgaagcagca attgtcatgg aaaacctaca tcaagaatac
    17941 gatctattcc tttcaccaac gactgcattt accgccccta aaatcagcga agatttgcaa
    18001 agtgatgcga taagagcaca gatggaacac atcagtgatt gttctgaagt agaaggttta
    18061 gacgttgttt cttccatgtt tgaggagagc ttgaagatca caccttatac acagttggct
    18121 aatctgactg gacaaccagc aatcagcttg cctactcatt tgacaaaaga aaacatgcct
    18181 ctaggaatcc aatttatggc tgccagagga agagaagatt tgctatttca aatcggctat
    18241 ctatttgaag caaatcatca gttccattta ccaaatccat ggaaatagca gaaacaagga
    18301 gaagaagaat gaagaaaaaa agattgtttg ctctaataac tagtgccttt tttattttaa
    18361 gcgcttgcgg tacagctgcc gctaatcagg aagataacag ctggagtaat gtagaaaaaa
    18421 agaaagaatt agtagtagcg acttctggca cactgtttcc cgcatcttat tataatgatc
    18481 aaaatgaatt agttggttat gatgtagatt tggcaaaaga ggtggctaaa cggttaaatg
    18541 tcaaaatctc ctttaaagaa tacaacgtgg atggacaaat cacttctgtt tcaaaaagag
    18601 aatcagattt tgctgcgaac gattttggta tcacaaaaga aagagaaaaa aaattctccc
    18661 tttcagagac tttcaaatat tcatttgaca gtatgatcgt acgaaaaaaa gatgattcag
    18721 gaatccactc acttgaagat cttaaaggga aaaaagcagc tggcgaaccc aatactagct
    18781 atatgcgttt agcggaaaaa cacggagcta aattagtcac atatgacaat gccacgaatg
    18841 atcagtattt aagcgatgta gcaaatggtc gaacagatgt tattctaaat gattattatc
    18901 tgcagaaaat ggccgtatct gctttaccag atatccctgt aaaaatactg gagaacgttt
    18961 atttcaatga aaacgaaagt ggttttttat tgaaagaagg aaatgatgct ctgaaaaaga
    19021 aaatcgatgg cgtattaaaa gagatgaaag aagatgggac gacaaagaaa atatctgaaa
    19081 aatattttca aactgatgtt tcagtcaaac cgaaagaaac gatggctgag tcggtgagtg
    19141 agtgatgtac tttcctctaa ttgatttttc cctcatgtgg acttcacttc ctttcgtact
    19201 gcaaggcttg gtatacacat tagggattgg cttcgtgtcg tttcttttag gaaatttggt
    19261 agggttgctt ttgacagttt taggtctttt ggattggctg cctctgaatg tatttattcg
    19321 tttttattta tcgttcttta gaggcattcc cgcactagtc ctgctgtttc tgttatattt
    19381 cgggttacct tatcaattaa gtgccttaac ggcttcagtc atctgcttta cgattaccag
    19441 cagtgcattt attggtgaaa tctatcgagg atcactagca ggcgtttctt caggtcagtg
    19501 ggacgctggt ttagcttctg gtttttcttt ctttggggta ttgaaatata tcgttttgcc
    19561 gcaagctttt cgaatctcag taccggcact cagtaacgta gctatggatc tagtgaaagg
    19621 tacttcgtta gcagcaacaa tcacagtgcc agaaatattt caaaaagcaa agatcatagg
    19681 cggtcggaca ttcgattatt tttctctcta tattttagtt gcactgattt attgggtcat
    19741 ttgtatcggg atcgaaaaag tgcaacagta tttagaaaaa cgttctatcc atcagtcaat
    19801 ctgaaaaata gaaatggtgc tagcgtggct ggcaccattt ctattttttg tttcttgtat
    19861 attctgccta gtattttaaa accatttcat gtaaaatgta aatcgaaaat atgttcggag
    19921 gtagaaaaca tgaagacccc gctaaccatc gaaatagaat cctcgttata ccaatattgc
    19981 atcgagcaag gcggcttggt tgtagaagaa gtcacgatgc ctgatgacca aggaattgta
    20041 gatacgctta gctgcttgac aaaatttgat ggaagccgag aatggcgatg ctatgagctg
    20101 aaagtgacaa aagcagattt tcgctctaca gccaaactgt catttgttgg acattataat
    20161 tattttgttt taccaagtaa actatatgaa gaagtaaaaa ctgaaatccc tacaggaata
    20221 ggtgttttag tgtatcgtcc gtacacggtt gaagaggaga tgcctgcctc tggtacattt
    20281 ctgattgcga aaaaagcagc aaagaaagag cttgctgtac cggaagaagc tttgacaaac
    20341 cgcttcatgg cttctttatt cagggaagta agaaaagcaa agcaaatgga gcgaggcgta
    20401 aaatattttc caaaagatca attgtacaaa gaattgaaaa gacgttcaga aaatcaagat
    20461 ccattttcta acgaacgata ttatgaacgg tttttagagg aaatagctag tcaggcaatc
    20521 aatgagttgc aagaagaagt tatcgcgctt cagcatgatt atgaatattt gaggcaacaa
    20581 cagcagatcc gtcggttgcc tacagagcca ttggagtgaa aaatatgtac tatccttatt
    20641 taagaggaaa acaatttgac ctattagcat taaaagaagc actgtcgcga ggattgctct
    20701 ccaataaaat ccaaccagtg atcgaaccag tacgtgattc cgctacgctt aaaaatgtga
    20761 tcgaattatt tcaaaaaaag caccatccaa tcgctgtgat ccaaaatccc caagtaggac
    20821 aattcaaatt attcgatcag catgtgcaca gttggacagt caaagaaaat agctctgtcg
    20881 tccctgcaca gatcttaacg ccagaaaatc tcagtgaagt actggattca cctccagcgt
    20941 ttcttgtttt cgatggacag cactacccaa aagatacaga ggtgtggaaa cagttggcag
    21001 gagttgattc gaaatttttg ataccagata ctagtcgctt tcgcatctgg ctgcccgaaa
    21061 acaaaattgt gatccgtgac tcttttcaaa cgagaaagca tgttgaaagt tatgcagata
    21121 aaacagatga cttttttagt gatgactatc tttttttcca cgcagacgga tatattggat
    21181 tttctgattt cacgatcgaa ggtagccgtt atttcgataa agggttccct agccgagcgc
    21241 ttgctatcca tctaacgtat attgatgctt acggcaatat acgcgtgaaa cattttgtct
    21301 ctgacagtaa cgactctgct aaagaccaag cattgaagtt tcttgaagca ggagataaaa
    21361 tgaaaaaatg gatcatgcgt caccatcatc aactcttgat tacttcagga atgattgaat
    21421 tattggctct ttaccagcaa caaaaattcc ctggactggg agtgttgaaa aagtggtcac
    21481 ttatgcatca tttggaactt attagtcacc tgctagatca tccaaaagat tggcttaaat
    21541 attattcaaa agttcaggaa ctatatgaag tgatccaatg attagataat gtaaatgaaa
    21601 aaggaataga aaagaggaaa ctggatgtat attcggcaaa caaggaaaga agaagtagaa
    21661 gaagtggtag aaatcattaa tgccgcagcg gatttcattg cttcgcaagg ctctcctcaa
    21721 tggcaaaacg ggcagaaacc aacaaaagaa acgattttga acgatattga aagaaaagaa
    21781 agctatgtat taatagtgga agatcaaatt gctggaacag ctgcattagt ctcaggcgtg
    21841 gatcccgttt acacaaaaat agatggtagt tggaaagaat caactggtcc ttatttatcg
    21901 attcatcgtg tcgctttagc agaaagtact cgaggaaaaa aactagcaaa accgttctta
    21961 gaacatttgt tgacgattgc agccagcaaa aatatccaag atatccgtat cgatacttat
    22021 ccagctaatg aaccgatgga aaagaccatc tattctgctg gattcactta tcaagggatg
    22081 attgaatttc cttttgaaca cggcgaaaga aaagcatatc aaataatcat caattgacta
    22141 taaaatcatc tgagcaaaga taaagacatt aacactactg aaaaaaacaa tcatatgata
    22201 gccaagaggt tgtaacagaa gtggccagct tcaaaaaaca agaaagaatt tccgaaaatg
    22261 cttctcaaat ttttgtggaa ttttagcgta ttttacgaaa tagctgcttt ctgaaactcc
    22321 cttcatcgag aggtcgtgac atagcttttg tcacgatctc tcggcttatc ctacgagtat
    22381 tattcgatac atttatatca ataatccttt ttttatttta tctgcagctt cttggaacgc
    22441 tccatcgttt gacacgacta aaagtgaggg gatagctttc aaacgtttca actgtgctaa
    22501 atcttctaca taaaccgcca gtctggctga aatctgttca gatgaatctc cacgtttttt
    22561 caggcgcgat tgcaatgttt ctttagagat cgtaataaag ataggacgga ctaccgtccc
    22621 gaaatactca tataaatgcc aaaaaccatt tgctgtcaaa acggcgtaac aatttcctac
    22681 tgtcagtttc tttttaattt ctgctttact ggaaccatat ttatgttgag catattggtc
    22741 ccactctgca aactcatttc ccttgatcat ctgattgaat gtattgtcag aaacaaaata
    22801 ataatcctct tgatcttttt ccccaggtct tggtgatcga ttcgtgtaag taatgatctt
    22861 ttgttccggc tgaaaaatag cttctgcgag tgaagttttt ccagaaccag aaggaccgat
    22921 aaatacatag caataattca ttgtcatttc tcctttgatg attgaacaag tgaaaaagct
    22981 ttggaaaata tttccaaagc ttttaaaagt aactttgctt ttttgtattt tataccagca
    23041 agccagtcac aatagcactt aaaaagctga ctaaagtcgc tgttagcaaa attttcaatc
    23101 cgtgttttgc gacaagattt cctttttctt catttaatcc cttcatcgca ccagaaatga
    23161 tcccgataga agagaagttg gcaaatgaaa cgaggaagac agatataatt gctgttgtac
    23221 gctcagtaaa atggaaatta ccatttgcta attctgtcat agcaacaaat tcatttgtaa
    23281 ccagtttagt cgccatgata ctaccggcat ccactgcttc tttccatggg attccgctga
    23341 tgaaggcaag aggggcaaag atgtaaccta ggatctcttg gaaagtgatg ccgaatatcc
    23401 cgtggaagat agcattgatc atggcaatca aagcaacaaa accgataagc atagcagcaa
    23461 ccgtgatcgc cacatggaaa ccatcaagaa tgtattctcc caacatttgg aaaaatgtct
    23521 gttctttgtt ttcttcaatg atcagctcat cttctttttc ttctaataca tagggattta
    23581 caattgaagc cagaatataa ccgccaaata agttcaaaac aagggcagtg atcacatatt
    23641 tagaatcgat cagtgccata taagatccga cgatcgacat agaaactgta gacatagccg
    23701 atacactcat ggtgaacaaa cgtttctcag ataggaaggg taattccttt tttatggaaa
    23761 taaaaacttc cgattgtcct aaaatagcag aagctactcc attataagat tccaatttgc
    23821 ccatcccgtt gattttactt aatcctagac caacagcttt cataaataat ggaagaatct
    23881 tgatatagcg tagaataccg ataatagcag aaataaatac aattggcatc aatacggaaa
    23941 gaaagaaagg tgcacttcct ttatttgcta caccggcaaa aacaaagtca acaccttgcc
    24001 cagcaaaagc aagaagatga tcaaacattt ttgccaatac agaaacaacc gctgtaccaa
    24061 aagttgtacg taataatacg aaaccaagaa caagctgtaa aacgaacatc acaattagtg
    24121 gtttcaattt gattgctttt ttgttactgc tgatcaaaaa agcaagccct aatgtgacaa
    24181 ataaaccaat aatacctaat aaataactca aataatcact cctattccaa attccgtttt
    24241 attttacctg ttttgcaaat aaaatactaa tctttagtga aattttcatt acttttttag
    24301 agtgaaacgc attcattttc cattagaaaa taaagcgaac aaaataaaag gtttaaaaag
    24361 tgtaacgtct tagtaaagtc tataaaaaaa cgaaactatc gattaagcta atagtttcgt
    24421 tttcaacatt tataagtaaa ctttttctat tggtaatata gattttcgga agggtagaca
    24481 ggtgcgcagg taatatcgat tcctagtttt ttcaatgttt gttcatcatt tttattgacc
    24541 atcacagtag agtgggcttg tgctccctca agttcagcta gtttatcata agcaacttga
    24601 gcgattggat tcgttactgc actgattgat aaagcgatca agacttcatt gatgcttagt
    24661 gcatccaaag aggaatgaag tgtctttgat ttcaatcctt gtattgtttc aagaactaat
    24721 ggtgacaata aaggaatgtc atctgcgata tgggctaaat gttttactgc atttaagata
    24781 actgccgctg acgcatccat caatgaactt gtacgcccgg taatgatgac ttcatctggt
    24841 aattcgattg caatcacagc agaaggatct tttgtaggac tttgcgcttg aatcttatct
    24901 gcatagtcat gggcagggac taccacgttt cggtcttcag gacgtaaacc gacttcttcc
    24961 ataatcagtt tgattcgatt aactgcttct tcgtcgatca atcctttttt gaagtcgcat
    25021 tctgtttgga aataacgacg gatgatttct tgtttagagg cttcttggac aacggtatca
    25081 tccacgatcc caaatcctac acgattcaca cccatgtcag taggagattg ataaacagat
    25141 tctttaccag taattttttc aataatacgt ttgattacag gaaatgtctc aacatcccga
    25201 ttatagttca cagctacttt attgtaggca tcaaagtgga aggaatcgat catattgaca
    25261 tcttttagat cgactgtggc tgcttcataa gcaatgttca gcggatgttt caacggaaca
    25321 ttccatactg ggaaagtttc gaacttggag taaccagctg catgtccttt ttggctttca
    25381 tgatacagtt ggttcaagca agtagcgagc tttccacttc ctgggccagg agctgtcact
    25441 acaacgattg gtttagttgt ttcaatatac tcattttttc caaaaccatc ttctgagacg
    25501 attttttcta cgttgactgg atagtcttcg atttctgagt gtttatagac cttgatgttt
    25561 cgtctttcta gtttattgat aaagactttc gtggcaggct gtccactata gcgagtgata
    25621 acgacactgt tgattaataa gccataacca cgtaattcat cgattaaccg caagatatcc
    25681 atatcataag taatcccata atcaccacgg atcttattac gttcaatatc tccagcatag
    25741 acgcaaatca gtatttcagc ttgatctttc aatttttgca gcaatttgat tttcgcatct
    25801 tcttcaaatc ctggaagtac acgtttcgca tgcttgtcgt caactaactt cccaccaaat
    25861 tctaaatata atttgtcata gtggttcact cgttccaaaa tatacgctga ctgctcttca
    25921 atatattttt ctgaatcaaa accaattttt ttcactaggt tccctcctta agtactaaag
    25981 cattttttca tttttttgag gattcgtcaa ctggaagagc gaaattcctc aaaaaaacaa
    26041 agaaaatggt ttaaaccaac ttgtctagat agttattcat tggtatgata gtttttgata
    26101 aggaaggtgc tacatgaaaa aaagacagaa aaagaaaaac gcatataaac actatatccg
    26161 ttcgattttt accggttatg aaagaatgct tgaagatccc gaattggaac aattgacgtt
    26221 tacttatcta aacgaagaaa cgcagctaac tcgtgatgag catcagcgca ttcatttcac
    26281 aacaagagat ctgcctagta aataaaaaat aagataaagg tcatcggatt cgattctgtc
    26341 ctatcagatg gaaagactag ttgatcgaaa aaaaggctgt accaaatttt ggtgcagcct
    26401 gttttatgga gcattgcccg ctctttttta taacaatttt ttacagaaaa tggtactatt
    26461 gaagtattaa taagtgaaaa acagatgagt aagaggaggc aagtagtatg aaagagccag
    26521 atacaaatgc aaattatgag ccagacgaac tagaggagac gaacgcggat caggatacag
    26581 gacaagaatc gtcttctttt tacgatatca aagaaaaagc aagcatgaat ctttcccaat
    26641 tattagaaga cttacaggct tttgaaaaag ctgtccgcga agaagatatc cctgagatct
    26701 accgtttata caatggccga ttgaatgaag aattaaaaag aagctcaaat gaaaatcacg
    26761 agatcgatca attgctgatg cgtaagatcc atgatcgttt tttacaggaa tttcctttta
    26821 tggaacaagt agaaaacatc tcgccaacga tgagctatta caaaatcggc acttattacc
    26881 atgatcggcc cacggtcggt attgatgcaa gtctgccaga aatttttgtt ttgcctaaga
    26941 tcgatgaaga gtgggagaaa tattcccaac cggagtcaac ggactatgac aaaaaaatca
    27001 atgagctaga cgcaaaggtg atcactgctc agacagaaat tgaacgttta gatgaacaaa
    27061 taaaagaaat caatcgacaa atgactgatt tgaacgacaa taaaggattc ttgaatcgta
    27121 aaaaaatcga ggaagaaatt caagaattag agaagaagaa gcaagtacta tctaatgaaa
    27181 aattaggctg gcttccttat attgagacgc ctgaaacaat ccagcagcaa aaagaagcat
    27241 tgaagcaaga agcaagagca gaccagcttc gtgcagccat cgtagaaaaa gaacaaaggc
    27301 aaatcagacg ctatttcggt agcaaagagg gattcggtca agcaatccat gaattcttga
    27361 tgaattatct tggcaatgag aatcctaata atcaatctaa tgaaggaggt tccgagtatg
    27421 aatgaacacg atgaagcaga atggacaaaa aatgaagaac aaacagaaga tcatgaagaa
    27481 acgaacactt cattggaaga acaaacaagt aatcctctgg atgacacaga agaaatccct
    27541 atgctagagg aaacaaaaat acatgaaaaa gaaaaagtaa ctccgacgaa tacgaatact
    27601 gcagaaaaca cccatgctta cgaaataact gaaaatcccg ggtatttaga aggaaaagag
    27661 caagatcatc aagatatcgt cagtttgatt gaaacagcgg aagcagaatt agcggattta
    27721 cgtatgagaa aagatttgat cgaatcagat tttccacaat tattagaatc atatgatcgt
    27781 tttatattga atgaagaacc aatctccacg atcggaaaga caagcctgat cgaatacttc
    27841 acgtatgaat tactgaaacc gttgaatgat attggtctgg aacggtcaaa ttcagcttat
    27901 gacacatgga aaacaagaca tttttcgatc aattatacgt tgaatggaca aaacgaatta
    27961 gtcttttcct ttgtattacc gaccatcgat caacgatacc aagtggaatc gatgagtctc
    28021 ctaaacgtat caccagagac aatggaaatc aatgtccaag atgaccgggt gctttctttg
    28081 atccgacact ggtcagtgga tcgagtattc tctgcagggc agatcacgat attcaatcac
    28141 aaattgaatc aattattagc ccatgcaaga acacttggtt ttaccgttaa tcagacatta
    28201 ctagacaata cgaagccact tcgtttgaat cttcagagcg aatttgaatt gacgaatgaa
    28261 gtattggatg atatttttat cgtggcaatg aaaaatccat cctacgatat ggaaaagatc
    28321 aacgaaacta cttatcaagt acgattagat aaaggacagt ctttaacgat aacaacaaac
    28381 gaaaaagatc aaacagtctt gtcgatctca tctggagact acccacgatc tgtcattgat
    28441 ttctttatca attacgaatt cttggtccca ttaatggtga gaaagtcctg attggataag
    28501 ttggattacc agatgtcatt cagataattc tgttccaaag gacttgcggc agttatccag
    28561 aataattgtc acaagtcttt tctgtatgta ctaaatggac gtgaataact tgctgatgaa
    28621 ggagggattt cattaggaat gtccacaaat aaaatagcac agcttagctt attgtctgct
    28681 gcttgtgtag caggtaggat cgcttttcaa tttattccga atttccagcc aatgactgct
    28741 atttttttat ttatagtact ttacttaagc ttaaaagatg cgttaattgt catgagtctt
    28801 tctattgcga tcagcagttt ttattttggt gttggaccat gggtcatcgg ccaatggatc
    28861 agctatactg ttgttctgag tttgttttca atcgtctgct tgagaaaaac agtgcaaagg
    28921 aatctatggt taaagggagt ctgttttttt ctggcgggca tggtttacgg aataggtatg
    28981 accgtttttg atacgctgtt atatcgtttg cctcaacctt ggatctatta ccttcaaggg
    29041 gtgtcgtttg atttgatgca cagtataggc aatgttgtgt tctttcttgt ttttctgcca
    29101 gtcgtcaaac gtttttacaa tcattcagga ggaaaaaatg aaaaaaataa tttatagttt
    29161 gcttgcaatg agtgtcagta tactcatttt gacaagttgc agtacaacct atacacaatc
    29221 ggcttccaac caaaaggagg aagtaaaaac atcgcaaaaa gcaacaatca cgttacaaga
    29281 aaatggtcaa aacttttcgg aaaaagaagt ggtcttcaaa aaaggcgatg atttactgag
    29341 tattttgaaa cgaaattttg aagtcaaaga agataacggc ttcatcactt cgcttgaagg
    29401 gcactcacag gatgagaaaa atcaactcta ttggatgttt actgtggacg ggaaaagtgc
    29461 tactactggt gccaaagaga tcaaattgaa tgatggacaa tcggtcattt tcaatttgtc
    29521 taaactataa gtttcataaa aaactgttaa agggcgaata ttgccataat tcagtgagtt
    29581 cagttgatga aagaaggaaa ataacatgga aaattttaaa aaaagcggaa tgttttccgt
    29641 aattgctgct ctaggggcta atattctagt tgctatcagc aaatttgtcg gctatgcaat
    29701 cagtggcagt gccgccatgc taaacgaaag catccacagt atcgttgatt gcagcaatca
    29761 gattttgctg ttattcggtg ataaacaagc caataaagga cagagcgagt tgcatcaatt
    29821 tggtgaagga cgagcaaaat actttttcag tacaatcgtc gcaatgatgc ttttcttcgg
    29881 cggtggggca cttggggtga tggaagcttt tgaaaagttg acgcatccat cccatgaagt
    29941 gggtaatccg atcattgtta tagcaatact gttatttggt ttggtaatcg aaggaagttc
    30001 gttacgcgtg gcaatgaaag aaatcaaaga attgaatact gaaaaacttt ccacgatgcg
    30061 ctttttgcgc gaaagtcgac acagtgaaat actgattatt tttacggaag acttgtgtgc
    30121 tgtaatcggt ttggtcttgg ctttagcagg aacaatattg acttatgcaa ccgggattgc
    30181 tgcatttgat gcgatcagcg gattgctgat cggtttcttg ctgatgggag ccgccatttt
    30241 cctagcaaaa gaattttata gtctgatcat cggtgaaagc gtgacagcaa gcgatttatc
    30301 aaaaatcaag ttagcttttg aacgtcctga gatcagtcgg ctgatcgata taaaaacagt
    30361 tcatttaagt ccaacggaga ttttagttgc agcaaaagca gatatcgttg gtaacaaaga
    30421 gaatgaagct tactcggtca tcaatgatat tgaaaaaaat atgcgtcagt ctcttcctga
    30481 caagaagatg tatatataca ttgaaacaga taaatatgac ccaaattatt ctcgtaaata
    30541 aaacgtttat tcatgaattg aagcaaaaat gagaaaaata taatcttgtt tttaaataaa
    30601 acggctacaa tttagcgaat ttatgttaca atgagtccgc tgtttatttg ttgtaattaa
    30661 aggagatatt ttaatgaaca aaaagaaaag tgcgccatgg cttcaagctt tgcatgcagt
    30721 gatgccactt tgtataagct atataccagt aggattagct tgcggagtat tgttgcaaaa
    30781 agttggattt gatcctctct tatcaggact gttatcgatt ctggtctttt ccggtggcgc
    30841 gcagttttta gttgcatcta tgcttacgac gcaagcatca tttgcaacga cattattgat
    30901 ggttttcttt ttagaattac gctatacatt attaggagca agtcttgccg gttttatgaa
    30961 aaaagaaaag cggacgtttt tggctgtctt ttctcaatca ctgaatgatg aaaactatgc
    31021 ggtgaactac ttaaagtttt caactgaccc ttcctggaat aaaagaaagg ctttatatgt
    31081 caattggttc tcaatgactg catgggccgg tagcaatatg atcggtaatt ttttcggctc
    31141 ggtgattcga gtagatgctg accttgtcca ttttgctttg acggccatgt tcattttcat
    31201 gtttatcatg cagatgaaaa gcgcactact gatctttaca ggtttattct caggcgtatt
    31261 aggggtcgta ttcatggtat tattccaaaa tactttcgga ttgattgcag caacagtcat
    31321 tgcttcattt gccggattta tgctggagaa ggcattcaaa aaagaaaaag ctaagaaact
    31381 aagagaccgc ggtaaagatg tcaatgagcc gctcttcaac ttcccggaac aggaggccaa
    31441 tcaccatgac taaactatat ttgctacttt tagttgcttg tctgttcatc gtggcatata
    31501 tcccgcgctt gttcccgatg ctttatttta ctcatcgaaa agtgccatcc tggttcagtg
    31561 actggatgaa atatgtaccg gtggcattat ttgcggcgtt agcttttaaa gatgttttca
    31621 ttactcatga acatctggat attgcttgga atatcaaaat agctgcaatg attctagtag
    31681 caggcgtggc ttacaaaaca cgttcgatgg cgttgtcagt tttgacagga cttgcgtctg
    31741 tctttttgct gtctatgctt taaactgttt tattttatta aaaacagaga ttgcgacata
    31801 agttgttcaa actgatctat ccgaactgca tttgcaacag tcaattctgg atgcaagttt
    31861 attcgtaggg ataaaaaaga ttagtgttgg cttatgatgc aagctctttt ttattttagg
    31921 aattagagag ggatttgtcc ttctatgatt ttttgctata atagggaaga tgtttatttt
    31981 atgaaagaat agttgaggga atttaaatga ataaaaaatt gatgcaagga acattttggc
    32041 taacctttgc taatcttcta tgtaaagttt taggggtagt ctatttgatt ccctggctaa
    32101 gtatgatggg gaacaatcaa gatggtatgc ttgctacgac attgtataat gttggctatc
    32161 ttccttatgg attgttcctg atgcttggta cagtcggatt tccaaatgcg attgcaaaaa
    32221 aagtagctgt agccacaaaa gaaggagata acgctgcttg tcggctgatt tttagaagta
    32281 cgatcaatat catgtttgtc atcggtatcg cctctgctgc actgatgtat ttatttgctc
    32341 ctttactagc cggaatcagt ccgattgcta acgttaataa tgggatacta gctatcagaa
    32401 gtttatgccc atctttgatt gctatcccaa ttcttagtgc aatgagagga tatttccaag
    32461 gaaaaaatga tctgcggcct tatggaactt ctttgattat cgaacaggct gtgcgagtga
    32521 tcgttatctt ggctggtact tattacttgc gcgtattgac tgacggaacc atattagaag
    32581 ctgtattgat cagtacagtc gcttctttct tcggtgggtt agctgcgatt atccatatgt
    32641 atatcgtcgg acgcagaaaa gacttcttcg aacttaaaga ttttttgatt tccagccgtt
    32701 atttcgaaag agaaaaccga tctgcctctg tctctatcat tcgggaaaca ctaccgttta
    32761 tttttgtcgg ctcagtcatt actatcgttc aaatgatcga ccaagtaacg atgaaaccac
    32821 tgcttcactt tttccgtcca gagatcgcag atcagcaact ggaattctta ttcagccgtg
    32881 cttctgtcaa tccaaataaa ttgacattga tcctgatctc catggtagga acagtagcta
    32941 taagcagctt gccaatatta agcacgatga agaaaaaaga tcggatacaa atcgaaaaaa
    33001 cagtaggaga tagtttttcg attgcgttat tgattcttct tccttcattg actggaatgt
    33061 ctttattagc tggaccacta tacacattgt tttttggcta tgatcctgaa agtgtcggat
    33121 atttccaaat ggctttgcta gcttctttgt ttttctcttt attcacgatc ctatctacga
    33181 tgcttcaatc tttgaatcac catcgttttg cgatccgatt aactgtagaa gcaattatcc
    33241 tgaaagtcat cttccaagta atcggattag gattagttgg cggatacggg atgagcttat
    33301 caaatggctt agcattcggt attgtctttg ttcgcggcta tcactttatg tgcaaagaat
    33361 accgaatagc acctttagca aagatcagca attttttctt aaaaactttc cgctccaccc
    33421 tgattatgct tgcagtatgt tttgccgttt tctttttgct gaatcagcga ttgtcaatgg
    33481 aatcaaaaag ctatgcaatg atttattgtg tggctgtagg aagtattggc ggcttagtat
    33541 ttttattttc tcaattcgga aaaaatgggt ttcgaatgtt gaaaaatgtt aaacatcata
    33601 gcagaagcaa agaataggtt aactaatcgt tttttgctgt cacttgaaaa acggcaactc
    33661 gtatgattac gcttgtcgtt tttctatttt ccaattttag tttcatatct aatcttactt
    33721 atgatatagt tataaggtct ggaaaaattc tttgaaacga ggaaattaaa cacatgaaac
    33781 ttgcagtagt tacagatagt tcggcatatc tgccggaacg tatcaagaac catcccgact
    33841 tattcgttat tccaatccct ttgattatgg atgggaaaat ttataacgaa ggaatcgata
    33901 tcgaagcgga tgaatattat ggacttttaa aaaacagtaa agattttcct actacttcac
    33961 aacctgtcgt aggggaagtt ttgggtttat atgaggaatt gaaagagaaa gggtatgaca
    34021 cgattttaag tatccatctt tcttcaggga tttctggctt tgtcaacaca ttatttgcga
    34081 tgaaagatga catcagcgga gtaacggtca ttccttatga ctctaagatc actagtatgc
    34141 cgatgggaca catggtagaa gctgccttag acttaaatga tgaaggtcag tcccttgatg
    34201 aaatacttgc acatatcgat cgaatccgag ataataccta tgcttatctg attgtagatg
    34261 atttgaacaa tttagtacga ggaggacgtt tgacaaatgg tgcagcgctg attggcagct
    34321 tattaaaaat caaaccgatc ctgacatttt ctgaagggaa aattgtttta ttcgaaaaaa
    34381 tccgttcaag taaaaaagca tttgctcgag ctgaagaaat tattggtaga agaaataacg
    34441 aaatacaacc gccagtcaaa ctttacgtga tacatgcaaa taatttagaa gtagcgattg
    34501 cggagaaaga gaaattgcag aaaaaatatc caaatgcaga aatcgaaatt ggtcatttcg
    34561 gaccagtcat tggtacacat ttaggtgaaa aagccatcgg cattgccatt tcagcgcaat
    34621 aattcctttt attcaaaaaa cataccaaaa atat
//
LOCUS       DAIGWC010000025        34410 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.025, whole genome shotgun sequence.
ACCESSION   DAIGWC010000025 DAIGWC010000000
VERSION     DAIGWC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.025"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(22..195)
                     /locus_tag="NOB74_001195"
     CDS             complement(22..195)
                     /locus_tag="NOB74_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1220395.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            643..3005
                     /locus_tag="NOB74_001196"
                     /pseudo
     CDS             643..3005
                     /locus_tag="NOB74_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            3373..4296
                     /gene="truB"
                     /locus_tag="NOB74_001197"
     CDS             3373..4296
                     /gene="truB"
                     /locus_tag="NOB74_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HCI1220396.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4300..5241
                     /gene="ribF"
                     /locus_tag="NOB74_001198"
     CDS             4300..5241
                     /gene="ribF"
                     /locus_tag="NOB74_001198"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HCI1220397.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            5593..6378
                     /locus_tag="NOB74_001199"
     CDS             5593..6378
                     /locus_tag="NOB74_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1220398.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            6391..7242
                     /locus_tag="NOB74_001200"
     CDS             6391..7242
                     /locus_tag="NOB74_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HCI1220399.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(7366..7818)
                     /locus_tag="NOB74_001201"
     CDS             complement(7366..7818)
                     /locus_tag="NOB74_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220400.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(8283..8651)
                     /locus_tag="NOB74_001202"
     CDS             complement(8283..8651)
                     /locus_tag="NOB74_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HCI1220401.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            8801..9283
                     /locus_tag="NOB74_001203"
     CDS             8801..9283
                     /locus_tag="NOB74_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HCI1220402.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            9320..10330
                     /locus_tag="NOB74_001204"
     CDS             9320..10330
                     /locus_tag="NOB74_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HCI1220403.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(10445..11158)
                     /locus_tag="NOB74_001205"
     CDS             complement(10445..11158)
                     /locus_tag="NOB74_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220404.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(11348..11938)
                     /locus_tag="NOB74_001206"
     CDS             complement(11348..11938)
                     /locus_tag="NOB74_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HCI1220405.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            12422..12649
                     /locus_tag="NOB74_001207"
     CDS             12422..12649
                     /locus_tag="NOB74_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HCI1220406.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            12665..13831
                     /locus_tag="NOB74_001208"
     CDS             12665..13831
                     /locus_tag="NOB74_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HCI1220407.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            14065..15108
                     /gene="hrcA"
                     /locus_tag="NOB74_001209"
     CDS             14065..15108
                     /gene="hrcA"
                     /locus_tag="NOB74_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HCI1220408.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            15202..15765
                     /gene="grpE"
                     /locus_tag="NOB74_001210"
     CDS             15202..15765
                     /gene="grpE"
                     /locus_tag="NOB74_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HCI1220409.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            15816..17645
                     /gene="dnaK"
                     /locus_tag="NOB74_001211"
     CDS             15816..17645
                     /gene="dnaK"
                     /locus_tag="NOB74_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HCI1220410.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            17796..18962
                     /gene="dnaJ"
                     /locus_tag="NOB74_001212"
     CDS             17796..18962
                     /gene="dnaJ"
                     /locus_tag="NOB74_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HCI1220411.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(19044..19709)
                     /locus_tag="NOB74_001213"
     CDS             complement(19044..19709)
                     /locus_tag="NOB74_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220412.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            19685..19858
                     /locus_tag="NOB74_001214"
     CDS             19685..19858
                     /locus_tag="NOB74_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220413.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(19903..20640)
                     /locus_tag="NOB74_001215"
     CDS             complement(19903..20640)
                     /locus_tag="NOB74_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI1220414.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(20642..22144)
                     /locus_tag="NOB74_001216"
     CDS             complement(20642..22144)
                     /locus_tag="NOB74_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HCI1220415.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            22403..24397
                     /gene="uvrB"
                     /locus_tag="NOB74_001217"
     CDS             22403..24397
                     /gene="uvrB"
                     /locus_tag="NOB74_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HCI1220416.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            24407..27223
                     /gene="uvrA"
                     /locus_tag="NOB74_001218"
     CDS             24407..27223
                     /gene="uvrA"
                     /locus_tag="NOB74_001218"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCI1220417.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            27486..28751
                     /locus_tag="NOB74_001219"
     CDS             27486..28751
                     /locus_tag="NOB74_001219"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HCI1220418.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            28755..29486
                     /locus_tag="NOB74_001220"
     CDS             28755..29486
                     /locus_tag="NOB74_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HCI1220419.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            29621..30505
                     /gene="rapZ"
                     /locus_tag="NOB74_001221"
     CDS             29621..30505
                     /gene="rapZ"
                     /locus_tag="NOB74_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HCI1220420.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            30502..31500
                     /locus_tag="NOB74_001222"
     CDS             30502..31500
                     /locus_tag="NOB74_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HCI1220421.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            31534..32469
                     /gene="whiA"
                     /locus_tag="NOB74_001223"
     CDS             31534..32469
                     /gene="whiA"
                     /locus_tag="NOB74_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HCI1220422.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            33012..33662
                     /locus_tag="NOB74_001224"
     CDS             33012..33662
                     /locus_tag="NOB74_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220423.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            33849..>34410
                     /locus_tag="NOB74_001225"
     CDS             33849..>34410
                     /locus_tag="NOB74_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HCI1220424.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT        11413 a         5818 c         7299 g         9880 t
ORIGIN      
        1 aaaaattcga ctttcttttt tctagtagta tataaatttt tgcatataga taaagatcaa
       61 gataccgata acggaagcta gattgtaatc tattttagtg acagtcaggt atagccaagt
      121 aactagaaga tcagtggaac ctgcaccata aaagtttgag tttgtcggtc cgttgacagt
      181 taaaagaaaa atcacgttga agttattgat atttccgatt acgccgcttc gatttggtca
      241 cgatccaaat tttggataat ccctgtagaa attagcatag tagctgggat accaattcac
      301 atattgacaa agataacaga gacttttaca taaaacggat caatcaggaa aggaattgct
      361 cgatccagcc ccagttttcc agcaatgtgt taactggccc agcgtcattc agcaaattat
      421 gcatgatgag gagcgaaatg aactgcggaa cagccattgt gataacgaca agttttttgg
      481 atcaatgtaa aaaacgtcag cgaaaggaaa aatttcgtgg ttttttatac ctgttcattt
      541 ggctagatat aaaatccaaa caaatgaaca gaagtgctta ttaggtttca attgggagta
      601 tctgcgctag aataagagta ataatgaaaa ggagtgttat gtatggatta ttctagtaaa
      661 gaatactttg ataaaatgac ggcttggtgg cgtgctgcta attatctttc tgttgggcaa
      721 ctttatctta aagataaccc cttactgaga cgtacactga aacccgaaga tgtcaaaaaa
      781 catccaatcg gtcattgggg aacgattcct ggccaaaatt ttatttatgt ccatttgaac
      841 cgagtcatca ataaatatga tttgaacatg ttttatattg aagggccagg acacggcgga
      901 caagtcatgg tatcgaatgc ttatttagat ggaagttaca cagagatcta tccagaagta
      961 acggaagatg agacaggaat gcaaaaatta ttcaaacgat tttcatttcc tggaggcatt
     1021 gcttctcatg cagcaccaga aacaccaggt tctatccatg aaggcggaga gcttggatac
     1081 tctctttcac atgcagtcgg agctgtatta gacaatcctg aagtaatctc tgctgtcgtg
     1141 attggtgatg gtgaagcaga aaccggtcct ttagctggaa gctggttctc aaatgtcttt
     1201 atcaatccag tgatagatgg agctgtttta ccgatccttc atttaaatgg tgcaaaaata
     1261 gccaacccaa cgatcttggc acgtaaatca gatggagaat tagcaaatta ctttaacgga
     1321 cttggctggg aacctttctt tattgaagga aatgattcag aaaaattaaa tcctgttatg
     1381 gctgaaaaaa tggatcaagc aatcgagaaa attaaatcca tccaaaaaga agctcgcctg
     1441 aagacagcaa cagatgtcgt gatgccaaaa tggccagtat tgatcgtacg cacaccaaaa
     1501 ggatggaccg gtccaaaaga atgggacggg gaaccaattg aaggaacctt ccgagcacac
     1561 caagtaccga ttcctgtaga tcaagaacat atggatcatg cagatgcttt actccgttgg
     1621 ctgaaatcct atgaaccaga aaaattattt gatgcacaag gacgtatttt agaagaaatc
     1681 agagaaatcg cgcctactgg tgaccaaaga atggcaaaaa atcctatcac caatggtgga
     1741 atcgatccaa gaccgcttat tatgccagat tggaaaaaat atactttgca atttgaaaaa
     1801 ccaggctccg ttaaagcaga agatatgacc gaacttggta aattcgttcg cgagatcatt
     1861 gagaaaaatc cagaaaattt ccgtatattt ggaccagatg aaacaaaatc aaaccgattg
     1921 aatcaagttt tcaaaacgac aaatcgccaa tggatggaaa aaatcgaacc agaaaatgat
     1981 gaatggcttt cgccatctgg tcgcgtcatc gacagtcaat tatcggaaca ccaagatgaa
     2041 gggttcttag aagggtacgt tctgactgga cggcatggtt ttttgcaagt tacgaatcat
     2101 tcttgcgagt ggttgactct atgttgactc agcacttcaa atggatgcgg aaatcacatg
     2161 acctttcttg gcgaaatgat tatccttcgc taaatctcat tgcaagctca acagtcttcc
     2221 agcaagatca caatggatat agccaccaag atccaggaat attgacacat ttggcagaaa
     2281 agaaggcgga gttcatccgt gaatatctgc ctgcggatgc aaatacattg ctcgcagtca
     2341 tggataaagc attccgctcg tcagaaaaaa tcaatttgat catctcttcc aaacatccgc
     2401 gtgctcaatt ttactcagca gaagaagcag ccgtcttagt gaatgaaggc ttgaaaatca
     2461 ttgattgggc ttcgacagca aaagaggagg aacctgaatt ggtcattgct gctgcaggaa
     2521 cggaatctaa cttagaagca ttagcagctg taactttgct gctggaagaa ttcccaaaac
     2581 taaaaattcg gttcatcaat gtcgtagatt tattgaaatt acgtcatcca agtcaagatc
     2641 cgcgtgggtt gagcgatgaa gaatttgatc aatattttac aaaagacaaa ccgatcttat
     2701 ttgctttcca cggttatgaa acattggtcc gcacgatttt ctttgatcgt cataaccatc
     2761 atttaatgat tcatggctac aaagaaaatg gagatatcac gacaccattt gacatgcgtg
     2821 tagtaaatga acttgatcgt tatcatttgg caaaagacgc agctttaaaa atcaaaggaa
     2881 gtcaagcaga agattttgcg aaaaaaatgg atcagaaatt acaagaacat caaaactata
     2941 ttcgtgaaaa tggtattgat ctgccagaag tattggattg gaaatggaaa aatcttgacc
     3001 aataaaatga taaaatcgat cccgcaaaat agaatttttt acattgatta agaaactgaa
     3061 aaaataaata aaaaaaacgg aaaaaagact ggaagaatgg ccagtctttt ttttcgtttt
     3121 tgggaagtga aaaccaaact atttacctgt aagccaccca taaatccaat caaatggtgc
     3181 aaagaaaaaa tcttccattc tattccctcc tttaaaaaag cataacatga tttctattta
     3241 cgtgagcatg aattttgtta cgtttttatt gccgaaaaat aaaaaccgtt cattatgatg
     3301 tcaaattcgt cagtaattga tgcaatgtgt tataataatt cagttaaatc aaaaatgaaa
     3361 tggagaaaag acatggacgg gttattacct ttatggaaag aacgcggaat gacaagtcat
     3421 gattgcgtat tcaaattaag aaaaatctta catacgaaaa aaatcggaca tgggggtacg
     3481 cttgacccag acgtagacgg tgtgttgccc atttgtattg gaaaagccac aaaagttatc
     3541 gaatatttga cagattctgg gaaaatctat gtaggcgaga taactctagg tttcagtaca
     3601 acgacggaag atcgatccgg agaacgggta gaaacaaaac cagtagatat gtctttatct
     3661 gaaaaaaaaa tagatgaagt gatggcttca tttattggtg agatcaccca gataccacca
     3721 atgtactcag cggtaaaagt caacggtaag cggttatatg aatatgcccg caataatgaa
     3781 acagtggagc gtcctgttag aaaggctcag atttaccgtt ttatccggac aagtgaattg
     3841 acaagagacg aagtgacagg aaccatttct tggcgcttcg aagtagaatg cgggaaagga
     3901 acctatgtcc gcacattagc tgtagataca ggcaagaaac ttggttaccc tgcgcacatg
     3961 tctgatctga cccgaacagc aagtgccggt atgtcccaga aggatgctct gacattagaa
     4021 gaagtagctc aagctgtgaa aaatgggaca atcgatgatt gtttgctgcc aatagaaaaa
     4081 ggagtggaac ggttcaaacg agtagatatt actgatgaag tatggcagaa agtaaaaaac
     4141 ggtatgagac ttgattatac tgtatttgcg ctcccagaaa tgccgtcaga agaaattgct
     4201 ttgttttata aaggaaaagt tgtcagtatt tatcagccaa acccgaaaga aaaaaacaaa
     4261 ttaaaaccta gtaaagtatt gagaaatgag gaataacgaa tgaatatcat caagatcaga
     4321 catccttacc aatcagaaca aattccagaa gacgatgtcg ttttagtgct gggatttttc
     4381 gacggcgtgc atatcggaca ccagaaagtc ataaagacag gtatggaaat tgcacaaaaa
     4441 gaaggattga aattagcatt gatgactttc aatcagcatc catctattgt ctttaaaaag
     4501 atcgatccta gcagcgtgaa atatttgact agccttaagc aaaaagaaga aaaaatggcc
     4561 gctttgggta tagattattt atatgaagtt gattttactt cttcttttgc tcatttagca
     4621 ccgcaggaat ttgttgatca atacatcgta gggttacatg caaaatatgc tgtttccggt
     4681 tttgattata cgtatggacc aaaagacatt gcagatgtcg ctcattttcc tgaatatgcc
     4741 aaaggaagat tcaaaatcgt cacagtttct aaagaagaag aacaaggtga aaaaatcagc
     4801 tctacccgta ttcgtggatt actagacagc ggacaagtaa aagaagcagc aaaactatta
     4861 ggttgcacat atgaggtaga aggggtagtt gtccatggcg atgcacgagg cagactacta
     4921 ggattcccta cagcaaatgt caaagtaaag agcacggttc atttgcctaa agaaggtgtt
     4981 tatgtgtcgg aaataaaaat tggggaaaca tggtatccag ccatgggttc aattggacat
     5041 aatgatacat tcggtgaagg acgggagctg actgtagagt tgtatatttt ggactttaat
     5101 caagatatct atggtgaaca tgtcgcggta cgctggaatc aatttttaag agatcaagtg
     5161 aaattttcta gtgtagagga attgattgaa caactcaagg aggatgaaca agcaacagct
     5221 gaatattttt ctcagcaata aaacattatg cataaaatct cttgtttatg tataactagc
     5281 aattacaata aaatgggtga taaataagcc caggaaaggg gctgtgacaa aagtcttgtc
     5341 acagcctttt tttccaaata aatggttttt cagaagtagc ttcttcggaa ataagccgaa
     5401 atttcttgaa gctgaccact tctgtcacaa cctctttctt tatagaaata aaaggacact
     5461 agcaattcat gaaaacgatt gctagagcgt atcatttgct ttagactata tatcttggtg
     5521 tacactcact ttaaggcgga aataaaagtt atccgtaata acaggtttag gtatgaaaaa
     5581 ggagtgggta ctatgtacaa ggaattagaa aacaaagtcg cagtagtaac tggtggctca
     5641 aaggggattg gaacagcgat tgctcaacga ttcgggaaag aaaaaatgaa tgtagttgtc
     5701 aactataact cggataaaga aggagcagaa aaagcagtca aagcaatcga agaggcaggc
     5761 ggaaaagcag tctctgtaca agcagatgtc agttctgaag aaggaataca gcgtttactt
     5821 gatacggctt tagaaaattt tgggacactg gacgtttggg ttaataatgc tgggatggaa
     5881 aatcagcatc caacccatga acttagcctt gaagattggg aaagagtgtt aaaagtcaat
     5941 ttgactggcg tttttatcgg aacgaaagcg gctttaaatt actttacaga gaataataaa
     6001 aaaggaaata tcatcaatat gtcttctgtt catgaacaga tcccatggcc aacgtttgct
     6061 cattacgctg cttcaaaagg cggggtaaaa ttatttaccg aaacggtagc aatggagtat
     6121 gcaccgaagg gaatcagaat caatagtata ggccctggtg ctatccgtac acctattaat
     6181 gcggcaaaat ttgatgatcc tgaacaaaaa gaactcttgg aaagtatgat cccactagga
     6241 cgcgtaggtg aaccaaaaga aatagcggcg acagctgcat ggttggcttc agacgaatcc
     6301 agttatgtta caggtattac actatttgca gatggtggga tgactttata tccttctttc
     6361 caaggtggaa aaggataagg gtgaataaaa atgggtttat tgattgcatt gatcccggca
     6421 gttggctggg ggatccagcc actgattttg aaaaagattg gtggcagacc aacaaatgag
     6481 atattaggaa ctggtattgg agcggtgctt gtcggcttac tcgttcaatt attcgcttct
     6541 ccagctggta tttcagtgac tacatttttg attagtttac tttctggtgc attttgggtt
     6601 attggacaaa caggacagta tacatctttc aacttgattg gtgtttctaa aacgatgcca
     6661 atttcgactg cattacagtt agtcggaacc tcgttgattg gtgtcttcgc ttttggagaa
     6721 tggtctggaa gtatggggaa aatcattgga gcagcagcaa tcattcttct tgtatttggt
     6781 tctgctttaa cggcaatcag tgatgatcct ggaaaaaaag gcggtatcac aaaaggaatt
     6841 agtctattag catcaacaag tattggttat tgggtataca gtgcattgcc taaactagtt
     6901 gatgcaagcg gactttccat tttctttccg caaatgatcg gtgtcttttt aggggcagtg
     6961 atttatgtga ttttccgtaa accaaccgca ttttctgaag acaagagttg gaaagcaacg
     7021 atcgttggag ccatctttag tgtgtcagca ttggcttata ttttttcagc aaatgaaaat
     7081 ggggttgcta ctgcatatat cattacacag ctaaacgtag ttatctctac attaggcggt
     7141 atgtacatcc tgcatgaaaa taagacacca aaagaaaaaa aattaacgat tatcggatta
     7201 ttgctgatcg tagtaggaag catggtcacg gtctttattt gaggataaag atggtaaaat
     7261 ttcatttatt aaaaaaatat ttgtttgaac caaacagtaa gtacttataa aaaaatagcg
     7321 ctagaatttc caacatctct ggaatttcta gcgcttttta attgtttaag atacaaggga
     7381 aatatctgtc tggatcaata atttttcatt gatccattga ctaaagttta cgacataatt
     7441 gaagttacca ccgattagta tctccgcatg attgtcttta taaagatcgt attgtaaaag
     7501 acggtctttt ttatttgcgt aaacatcgtt atggtactgg actaattgtt ctcggaattg
     7561 attgattgct gtaaaatcac gatattgaag gttgaaacgc atcgtgattg gtgcatttag
     7621 catgaatcgc tgcatttctt ttgctgcttc ctctgcttga tctccgtata ggaactcaaa
     7681 aagattacgt tcagaaaatt tccattgccc gccaaccttt gttcctttta gttttccttc
     7741 atgaagataa tttctgatag aacgtgtagt aacacctaat tgttcggcta attcatttac
     7801 tgagtaaaaa tctttcaatg ttcaccctcc tatgtgaatg gttctactga cttagttgat
     7861 atttgcttaa tcacgaaatg tagaaagaac gattttaatt aaggtcattg taaaaatcaa
     7921 gtcagaaaat tctaactttt atttctctaa agaaattcgt tctctcctaa agtgatatta
     7981 tatttaaata tacctgaaaa taatgggcag tattatgaaa gatcactgat attttctcgt
     8041 attttttcct tattcaaaag ttttgcagga aaattgctga aaaaataatt ttactaagta
     8101 gaaaattcaa agccattcaa tcagtgattt ttttcagcac aagaaagact ccttataaaa
     8161 atagcagata ctttgtcaat taagtgttta accagggatg ataaaaagga taggattgaa
     8221 caaaacctgt ataaggtgat gaatagtttc ctcgccagta aaaggtttat tcgtataaag
     8281 ctttatcgcc aaaatttatc atgacctttt ttatcttcaa tattaaatga aatcaattgt
     8341 tcaatcaatt cccagttgat tacacttttc caaggaactt tgatgacgtt atccgtatat
     8401 acgtagcctg cttcttggat atttttttca agggcacgaa tcgctgcttt ttccggtgcg
     8461 atagaaaaat gatttttagc aaaactaaat gcaataataa aggtaccatg gtcagtaaac
     8521 ataggttggt tccattttac agttgtgtct agctggggat acgtttctgt tatcttagca
     8581 aaaaggtctt tgatcttttg ttgatgttct ttttctttga tttgattgat gatcggctga
     8641 aatttttcca ttctaaaacg cctccattaa gtggtttgat ttattttacc agaaaaacaa
     8701 tagttatgta taaaaaacga acaaaacaca agtaatgttg taaccgctat atttatatga
     8761 taagatgtct caaataataa aatagaaaag agacataaaa atgattgact tggcaaagaa
     8821 attcttacac gaaaatatat attttgagtt gtatcatcat cgagccattt atacaaatga
     8881 agatgctttg gtaataaaga aagaacaagg atttacaggt acagagacca aaagcttatt
     8941 cttaaaagat aaaaaagata ataactacgt atatctgact tttactacga aacaaacgga
     9001 tttcaaagca ttagggaaga tcgtcggtaa aaggctttct attgtttcat cagaacgcat
     9061 ggaagaacaa acgggacaaa agcagggcgc tgtttctccg tttggttatg aaaaacagat
     9121 tccgattatt attgatgaag agctcttatc aaatgaaaaa cttgtttttg caccaggtag
     9181 accagatcaa acgatggtca tccaaacggt tgacttaaac aaaatcatcc agctacttga
     9241 gatgccgata tttttgatgc cggcaaacga aaaaaacaat taaccaagta aaatagtgca
     9301 tacttggagg tgaagcaaca tgataagtta tccattatta gaaagaaatg caacgattgg
     9361 ggttactgca ccatcctcag gcgtatcaga ggaacaccat tcgttactcg aatcagcttt
     9421 aaagagaatg gaagaaaaat ctttccaagt agttactgga aagacgcttt ggacgcaaga
     9481 taaggaaaaa tcaggtccag caagaaaacg agcagatgaa ttcaatcaaa tgatgcaaga
     9541 tgaaaatatc caaatgatct ttccgacttg gggaggagaa ttattgattg agattctcga
     9601 ttttgtcgat tttgatgctc tacaaccaaa atggatagta ggttattcag atattagtac
     9661 gttgctactt gctgtcacat taaaaacagg gatagccact gcacatggaa ctaaccttat
     9721 tgatttaaga ggagagtact tggatgaaac gacagcaatg tgggaaagtg tactgaaaac
     9781 aagagaagga gaatcgattc tacagcaatc ttctgaaaag tatcaaaaag tgtggcccca
     9841 tgagcattca tcatcttctg ttttccatct cactgaacca acaaattggc aatcagtcag
     9901 cggagatgca gtaaggatga agggacgatt attaggtggt tgtattgata cgatcaggca
     9961 tttaatcggt actccttatg gagatgtcca atcttttaaa agaaagtata atgatggaaa
    10021 gccgatcttg tggtttctag aaaactgtga gctatcgtca gttgatttaa gaagatcact
    10081 tgttcagatg aaactggcag gctggtttga tggcagctcg gggatcatgt tcggtagaag
    10141 tgcggcagag gatttgttag attataaaat gaaggatgta tacgaagatc tgtcaaagga
    10201 attaaaacta ccgatcttgt atgatattga ttgtggtcat gtaccgccac aactgacatt
    10261 gattaatggt gcctatgcag aagtagcggt agaagataga aaagcgactg ttttgcaaac
    10321 gtttatttaa aaaatttttt cctgccttgg agtctatcaa agaccaataa atctaaatag
    10381 aaaagaaagt gaaagaagct gacaaaatgc tgtcagcttc tttttgtata acatattaga
    10441 aagtctaatt atctataact gtcacatcga ttaactgttt cacgtcattg ggatttcctg
    10501 taggaatagc tactacagat gcattatcaa tgatttcttg agttgtttct ctaatgaacg
    10561 ctggataaga tgtttgatct gcaggcattt gccaatgtga aggaactgga taactagtga
    10621 ttgtcccgtc atggttactt gaatacacta aaactccctg gtaactgtat ttcccagtga
    10681 gcataaccac atctttcgga tagactgcac tccctgcatc ataaggggcg ataggtgttc
    10741 ctgcaggata atgaataaca tgtaattcga aatcacccga tgtatctcta aaagtattac
    10801 ctctaatagc tagccaaaca cgtgcgtact caatttgtag atcagaatat cctgctaacg
    10861 gatctattga ctgagaagac tgtgaggagg ttgtgtctat tgttgaagaa gaaatatttg
    10921 tctcaactgt actactagat gtagaagaag tattgggctc tgagacttta ctgcttgttg
    10981 aagatgtatt cgtttcagta gaagctgatt tctgagtact tgatttttca gctgaactgg
    11041 tttgtctgat tgaacttttg tctgtggtcg cagatggatc actattttct ttactaggag
    11101 acgtacatcc tacaaggaat aaagagacca acaataaaat aaaacctaac tttttcatat
    11161 aaaatacctc attatttttt taataccagt atagcataat cctgaatttt tgaatccgta
    11221 aaaccttgtc tatgaatata aatagagtgt atcttctttg ataaatgtca gaaaaagtgt
    11281 gacaaataat catcagtaaa attacttgtc acactattga taaggagtat ttaattgaag
    11341 agaatgatta ggagaaagga tctccgtact ttttatagta atcatagaat ccaagtttgt
    11401 atagacgaat cgttttttct cttatttctt ctgtttcaaa atggactgct tgaagaatca
    11461 agtctgtgaa ttctatagga gctgttccat tcgcagtaat caaattacga tctttcacag
    11521 cttgttgttc tataaaatct tctttattct gataattttc cgattctaac caaggaaatt
    11581 gcgcatttcc ggtgtgtttg taaccttgca ataatccgct ctgagctaaa taatcaactg
    11641 ccccacaaat agcagctact ggtacgtctg tttttaacaa tttatcgatt atttgatata
    11701 aatgatgatt ttttatgtcc catgaattgc caccgatcat aataaaaagg tcaacttttt
    11761 caggtatttg ttcgattaag taatcgattt ttgtttttaa tcctccaatg gaagtgacct
    11821 ctgattggat agaagcagtt ttgttttgcc atttctcatt ttggtttagt gtgctagtaa
    11881 tataagcacc ttcccaatcg gcatattcct ctaatagaaa cgtaatcgca gttttcattt
    11941 tcaagctctc ctttactatc tataacaagg acaacagttt taacctacag acattcatta
    12001 aaattgggta gcgacagcga aaacaacaat tcttaagttt tagacagagt atacagatag
    12061 tcaacttaat taaatacgaa ctaaataaaa atgacaggta atcatttttg tttaccagca
    12121 ttataacatt ttgcatacat ggatgacaaa agaaccaatt cccacttgct tgagtacaat
    12181 attaaaagaa actggaaggc aaaaagtaat tatagaaacg aaaaataaat catatcgggc
    12241 actcagacat gaaaacaacc ctagagatat ataactaggt aaccagttta atgaaagaaa
    12301 aaatcatcca agaagtcgat tcttggattt tttagtggat ttgttcgcca aatacgttta
    12361 gtatgcgtat atgagaggtt gtaagcaaag cgttgtggtc tgagcactta aggaggaatc
    12421 tgtgaaaata gcttttcata tttttgcaga ttttgactta atgccgaagg tcagctttgc
    12481 gattaccgtt tatcgagagg ctgtaaaagc accgtgtagc tccgatgaca ataagcaagc
    12541 atttttagag ctaggtttcc ttgattctaa atatgcggct tatttcaatg agttggtgct
    12601 tgaacgcgat tttaagaagg tcgaaaacag gcacgacttt tcgacgtaag gagaaagaat
    12661 ttcaatgata gaaacaataa atcccgcaga aaacaaggtt tctgcgtaca ttcatatccc
    12721 attttgcgag catatctgct attactgtga ttttaataaa gtttttttag aagggcagcc
    12781 agtagatgag tatgtggaaa tgctgctgaa tgaaatgaaa ataatgctag aaagtcatcc
    12841 gacagcgaat ttagaaacac tttacgtagg gggcgggaca ccaacttctt tatctgctaa
    12901 acaacttgat cgactgttat caggtgctag agagatcctg ccttttcaaa atggtaatga
    12961 gtttactgta gaagcgaatc caggtgattt gacccgtgaa aaacttcaag taatgaaaaa
    13021 ctatggcgtc aatcgtttat ccatgggagt gcagacattt gataatcgct tattgaaaaa
    13081 aattggacgt aaacacaccg cagaagatgt gtatcaaact atgcaatttt tagaagcaga
    13141 aaattttacc aatgtaagca tcgatttgat ttatgcatta ccgggacaaa cactagaagg
    13201 atatctggat actttggaaa aagctttggc tttggatctg cctcactatt ctttgtactc
    13261 attgatcctc gaaaacaaaa caatgttcat gaactgggta cgacaaggaa gactcgaact
    13321 gcctgatcag gaaacggaaa ccagaatgtt tgaagagacg attgaagcaa tggaaaagca
    13381 tggacgtcac caatatgaaa taagtaactt tgggctctcc ggacatgaat ctcaacataa
    13441 cctcatgtac tggaacaatg cccactattt tgggtttgga gctggtgcta gcggttatct
    13501 tggagatatt cgttaccgca acaaaggacc aatccaacac tatttacgcc cattacgagc
    13561 aaatgaacgc ccggtattgg aagaagaaaa attgacacga aaaaatcaaa tagaagaaga
    13621 aatgttctta ggactaagaa aaaaaacagg gattactaaa aaacatttct atgatcgcta
    13681 tcaaaaaaca attgaatcgg tgtacggtga tgtgctaagg gaattagagc aagaagggtt
    13741 acttgttaat gaagaagacc gtgtttattt gacaccaaga gggacctttt tggggaacaa
    13801 tgtgtttgag cgctttttgt ttgaaaaata gtttaaagaa tatttgtttt ttatctgaat
    13861 ttaaataaaa aaagttcaaa aatacaataa aggactattg aaacgttgat ataactggat
    13921 ttacatcaat tatttagaat tagcactctt gtgtttagag tgctaaaaaa tggagtcttt
    13981 ctcttgacag gagaagggct tcttgctata tttataagtg gattagcact tagaatatat
    14041 gagtgctaat gagaggtgag gaagatgtta acaaagcgac aaaacgacat tttacgtctg
    14101 atcatccaac actatacgag tagtggcgtg cccgttggtt ccaaaacatt gatgtctgag
    14161 ggagtcaagg ccagctcagc aacgattcgc aatgatatga aagcattaga agatgaagga
    14221 ttgctgttga agactcactc ttcttctggg cggattccat ctgctttagg ctatcgttat
    14281 tacgtggatc atttgttaaa acctgctcgc gtagcagaag atgatttgct gctgattcgt
    14341 cagtctctag gcagagaatt tcatgaaatc aatgagatta ttaagcaatc tgctgagata
    14401 ttatctgagc tgacaagcta tacgactttt tcattgggac ctgaaataaa agaccgccga
    14461 ctgactggct ttcgtatcgt acccttgaat aatcgacaga ttattgctat cgtcgtaaca
    14521 gatatgggga atgtagaaag ccaagtgttc actcttcccg aatatatggg aagtcaggaa
    14581 ctagaaaaaa tggtacagat tgtaaacgac cgtctagtcg gagatcctct gatgacggtg
    14641 taccataaac ttcgtacgga gattccgatg attcttcata aatatttcca aacgacagaa
    14701 gggatgtctc agttatttga caccgttctt ggtcatgttt ttgaagataa ggtttatgtc
    14761 agtggacaaa tgaatctctt ggattatgag ccccgtcaag atcttgatca gttcaaatcg
    14821 atgttttctt ttatgaaaga ctcagacgga cttacacaaa tgatcactcc gatggatagc
    14881 aatattcata tcaagattgg tgctgaatta ggcaatgatt tattgcagaa tatgagtatg
    14941 attcaagcaa gttacgagat agatggtcat ggaagaggta caatagcctt gttagggcct
    15001 actagtatgc cttattctcg gatgttcggt ctagtcgatg tttatcgaag agaactagca
    15061 gctaaacttg ctgattacta ccgttcgctt gacttgtcaa actcgtaatg tgaataacga
    15121 agctatttgc agctgatcgt tctctctttc ttagtaagag caatcaaaca gctgactgaa
    15181 taatgaaagg aagactgtat cgtgaaagaa aatcaagaag aactagataa agaaatgaca
    15241 gatgctcagc cagaaccgga aatcgatgtc gaagctgcag aagattcggg tatttcagaa
    15301 gctgaagcgg aagaattcga aacagcgaaa ttaaaagctg agttagaaga aatggaagat
    15361 aaatacttgc gggctcgtgc tgaaatcgca aatatggcaa atcgaggaaa aaatgagcgt
    15421 gagcaattac aaaaataccg ttcacaagat ttagccaaaa aattacttcc atcaattgac
    15481 aacctggaac gtgcattagc cacagaagtg tcagatgatc aaggggcagg tttgaaaaaa
    15541 ggcgtggaaa tggtcttgga aagtttgcgt aacgcactgg aagaagaagg aattgaaaaa
    15601 atccctgcta aaggagaagc ctttgatcct aatcttcatc aagcagtaca aactgttcca
    15661 gcgactgaag atacaccagc cgatacgatt gtagaagtac tacaagaagg ctacaaatta
    15721 catgatcgcg tgttaagacc aaccatggtc attgttgcac aataattgtg cggatataaa
    15781 acttacactt tcaattaaag aaggagacgt taattatgag taaaattatc ggtattgact
    15841 taggtacgac taactctgca gtagcagtat tggaaggaaa cgaagcaaaa atcatcgcta
    15901 acccagaagg aaaccgtaca acaccttctg ttgtatcatt caaaaatgga gaaatccaag
    15961 taggggaagt tgcaaaacgt caagctgtga caaacccaaa tacgatttca tcaatcaaac
    16021 gccatatcgg tgaagcaggt tacaaagtag atgtagaagg taaatcatat acaccacaag
    16081 aaatctcagc aatgatcctt caatatatca aaggattcgc agaagactat ttaggtgaaa
    16141 aagtcgaaaa agcagttatc actgtgccag cttactttaa tgatgcacaa cgtcaagcaa
    16201 caaaagatgc tggtaagatc gctggtctag aagtagaacg tatcgtcaat gaaccaactg
    16261 cagctgctct tgcctatggt ttagataaaa cagatcgcga cgaaaaaatc ttagtattcg
    16321 accttggtgg cggtactttt gacgtatcta tccttgaact aggagacggt gtctttgatg
    16381 tattgtcaac agctggcgac aaccatctag gtggggacga ctttgataac aaaatcatcg
    16441 actacatggt agcagaattc aaaaaagaaa acagcattga cttgtctcaa gacaaaatgg
    16501 ctttacaacg cttgaaagac gctgctgaaa aagcgaaaaa agatttatct ggcgtatcaa
    16561 gcacacaaat cagcttgcca tttatcacag caggagaatc tggaccattg catttggaaa
    16621 tgacattgac acgtgcaaaa tttgatgaat taacagctga cttagtagaa cgtacaaaag
    16681 taccagtacg tcaagcgcta aaagatgcag gtttatcaca atcagaaatc gacgaagtta
    16741 ttttagtcgg tggatctact cgtatccctg cagttgtaga agcagtacgt aaagaaacag
    16801 gaaaagaacc aaacaaatca gttaaccctg atgaagtagt tgctatgggt gctgctatcc
    16861 aaggtggcgt gatcactggt gatgtgaaag atgttgtttt acttgacgtt acaccattgt
    16921 cattaggtat cgaaacaatg ggtggagtgt tcactaaatt gattgaccgc aatacaacga
    16981 ttccaacaag taaatcacaa gtattctcaa ctgcggcaga taatcaacca gcagtagaca
    17041 tccatgtatt acaaggtgaa cgcccaatgg ctgctgacaa caaaactcta ggaagattcc
    17101 aattgacaga tattccagca gctcctcgtg gtattccaca aatcgaagta acattcgata
    17161 ttgataaaaa cgggattgta aatgtatctg cgaaagatct aggtacacaa aaagaacaaa
    17221 aaatcacgat caaatcttct tcaggtctaa cagacgaaga aatcgaacgt atggtaaaag
    17281 atgcagaagc aaatgcagaa gcagataaag ctcgtaaaga ggaagttgac ctacgtaatg
    17341 atgtagatgc attgctattc tctgtggaca aaacattgaa agaattagaa ggcaaagtgg
    17401 acgaagaaga agtgaaaaaa gcagaaacag ctcgcgatga attgaaagcc gctgttgaag
    17461 caaacaacat cgaagaaatg aaaactaaac gcgatgcatt gaacgaaatc gttcaaaact
    17521 tgactgttaa actatacgaa caagcggcac aacaacaagc tcaagaaaac ccagaagcag
    17581 ctcaaggcgg agcagatgat gtcgttgatg ctgattttga agaagtcgat ggcgacgata
    17641 aataatcagt tcactgaatt tcgagagaag gccaaagttg ctactttggc tttttctttt
    17701 gaaaaatagt ttgaagtatc ggtttttgtt tcaaacaaaa tatgatatga taacaagcga
    17761 cgtgaaaatg atgagaacca ataggaggaa agcctatggc aacaaaacgt gattattatg
    17821 aagtcttagg gctctcaaaa ggagcatcag aagatgaaat aaagaaagct tatcgtaagc
    17881 tttcgaaaaa ataccatcct gacatcaata aagaacctga tgcggaagaa aaattcaaag
    17941 aagtatcaga agcatatgag attttaagtg acccgcaaaa acgcgctgca tatgaccaat
    18001 acgggcatgc aggcacagat ccaaattacg gtgctggtgg agctggtggc ggatttggtg
    18061 gattcggcgg cttctctggt ggcggcttcg gtggttttga agatatcttc gactctttct
    18121 ttggaggagg cggtcggtca gtcgatccaa atgcgcctcg tcaaggtgct gatttgcaat
    18181 atacggtcga cttgtctttt gaagaagcga tttttggtgt agaaaaagaa atcaagtata
    18241 atcgggaaga aatctgtcat acttgtggtg ggaacggtgc aaaaccaggc acacaaccaa
    18301 ctacttgtca taaatgtcat ggtgcaggta cgattaatgt agaacgccaa acaccacttg
    18361 gacgagtgat gagccgtcaa acttgtgatg tttgtcatgg gacagggaaa gaaatcaaag
    18421 aaccttgtcc aacctgtcat ggctcaggac atgagaagaa agcacattca gttaaagtga
    18481 atgtaccagc tggtgtagaa gaaggacaac aaatgcgttt agctggtcaa ggagaagctg
    18541 gagaaaacgg cggaccattt ggtgatttgt atgtggtctt ccgtgtagaa gaaagtgata
    18601 tctttgatcg tgaaggttct gaaatttact atgaattgcc tttaagtttt gtacaagcag
    18661 ctttggggga tgaagtccaa gtaccaactg tccatggaga tgtgaaattg aagatccctg
    18721 ctggaacaca gacaggtacg aacttccgtt tacgtggaaa aggcgctccg aagttacgtg
    18781 gtggtgcaac aggcgaccaa catgtcaaag taaaactgat cacaccgaaa aatctaaatg
    18841 aacaacaaag agaagcatta cgtgcattcg ctgaagctgg cggcatcaaa gttgaagaac
    18901 agcaagaaga cggtttcttc gataagttta aagatgcttt tggcgggaaa aagcggaagt
    18961 agtttttcta gtaaaaacgc taagtcatta ataattaaaa accagacgaa caatcatatg
    19021 ttcgcctggt ttttttgtag ttgtcatgtt tgtaccaaca aaaaagccag ctttagaata
    19081 tgataatcgt catagtttct aggggtataa ccagtgagag aatggaactt gttcaatcga
    19141 tattgcaagg tgtttttatg aataaataat tcttctgagc aatttttgat gcttccgtta
    19201 tttttactga agcatgccaa agtcttcttg aacaaatgta cttcttcttc tgtcaggctt
    19261 ttcaaaatac gttttacata taatgttcgt tgatctgacg ggattgctgg taaaacgatc
    19321 ccgaggtcta aatcttcaaa aaagcggatc tcgttcacag attgatggaa agctatccat
    19381 tcgcaaactt gtttggcatg aaggaaagat tgcggtgtct cttgctctgt ataacaaagc
    19441 gacccaattc caaagtttag ctgtaactga tacattttat taaactttgt ctggatttta
    19501 tcaagcaatg atagcaatga ggctctggaa atccgattga ctaggataat gatttgttgt
    19561 ctatgtacag tgagcaaagc ctgtccgtaa taagagaaga ccctttcgag caactccaat
    19621 aaaggattga tccgttcttg acacaattgc tgattgtcag aaagttgtcc cacaactaca
    19681 taatatggag aagaaaaatc aagctcaatt aagtgagggt ggtatcgact atgtacttga
    19741 tatcatcaat gaaccgatgg tactttctta tgcgatggaa caggtagagc gattgcttgt
    19801 ttgtgcagga aaacaagcga tgcggctgat acgattaggt gagaaaataa gaagataaaa
    19861 atacacggtc ccttcatggc gaccgtgcat ttttggtttt tattaaatat ttaatacttt
    19921 attcaagaaa tcttttgtcc gttcattttg cggattttca aagatttgtt gaggcgttcc
    19981 atcttctaaa aagtttccgt cgtcaatgaa catgacgcga ttggccactt ctttagcgaa
    20041 ccccatttcg tgcgtaacga taaccatcgt cataccttgt tctgctaact ttttcatgac
    20101 gttcaagaca tcaccgacca tttcaggatc gagtgcagaa gtaggctcat caaaaagcat
    20161 gatgtcaggg ttcatcgcta gagcacgagc aatagccaca cgctgttttt gtccaccaga
    20221 aagcatttca ggatacatat cttttttatc ttctagacca actgtctgca gtaatttgat
    20281 tgcttttttc tctgcttctt ctctagattc tttcttcagg tccatcggtg ctaaaatgat
    20341 gttttccaaa atagaaagat gagggaatag gttaaagtgt tggaatacca ttccgatatg
    20401 ttgtctcacc aagttgatat ctgtgctttt atccatcaag tgggcgccgt caataataat
    20461 ttcaccgtca gaaggttctt ctaaacgatt caagcaacgc aagaatgtac tttttcctga
    20521 acctgaaggg ccaatgatac agacgacatc tccttcgttg atggatacat tgatgtcgtt
    20581 taatactgtg ttatcgccgt attttttgac taaatgctca actaagattt tttctgccat
    20641 cttacttcac cttcttttct aaaacttttg ctaattttgt caatgctgtg atcaaaatca
    20701 agtacatgat cgcaatgatc aagtaaacat acgtactttg tgttgtacgt gcaacaatga
    20761 tcttaccagt ttgcagcaat tcgactacac cgattgcgga aatgatcgtt gtgtctttta
    20821 atgagataac gaactgattg acgaatgatg ggatcatgat gcgtatcgct tgcggcaaaa
    20881 tgattttttg cattgtccga ttataagaaa gacctaaact tctggaagct tccatttgtc
    20941 cgacaggaac ggcgttgatc ccgcctcgaa caatctctgc gatataagca cttgcgttaa
    21001 gagtcaaggt gataacacca gcaaggaagt caggaatcgt aaatccaacg ataccaggca
    21061 acccaaagaa aataaagaac gcaagaacca tcattggaat tcctcggatg atatcgacat
    21121 aaatactagc aattgtgcga agagcgcgta ttggtgctac actgaataat ccaaaaatca
    21181 caccgattac tatagccaaa gcaaaggaga tcaaagttag gagaattgtt ctccaaagtc
    21241 ctttcaacaa tgcttgatag ttgttttgga taagtccaag aaatgttgat tcatcagcag
    21301 tggaagactc actggaagtt tctgaaccat ccgctacata ttctttaata atcttatcgt
    21361 attcgcctgt tctttttaat tctttcaatc cttcattgaa catattaaga agctcaggat
    21421 tttgtccttt tttaacggca aatgcatatt ttccgccaga ttcttttttg atcggtgttt
    21481 ccaattcttg tccttgtttg atcgcataac cgattaccgg ataatcatcc atcattgcat
    21541 cgattgcgcc aacttttaac ccgtcgtaca attgatcagc agcatcaaaa tatttgatag
    21601 aatagccata ttcagattca tggtcgctta aaaattcagc actttcggta ccaacttttg
    21661 ctccgactgt ttttcctttc aaatcttcat aagacttgat cgaagtatct ccttttttga
    21721 cagctaattg gatcccgcta tcaaagtaag aatcagaaaa atcatagctt ttctttcgtt
    21781 catctgttac agtcattccg gcaatcattc cgtctgcttg tcctgattcc aaagcttgca
    21841 aagcagcaga gaaaccacgg tagtccattc ggatgttaaa tccttgcagt ttggcgatgt
    21901 tttccatcaa ttttacatcg atgccttcgt actcgccctt tgcgttttga aattcaaatg
    21961 gagcaaaagc agagtcactg gcaattacgt atacgtcttt tttgggctct attttttgca
    22021 ttgtctcgct tgtgcttgac tctgccgttg tagtgttgtc agcttgtgca acatgaccaa
    22081 acgcaagtgt cacaagtcct gtcattaaga aaacaaatga gtgaaataaa tgctttcttt
    22141 tcataatcaa cctcctaaat ttccaatatt ttattattat aggcgaaaag tgctgaatca
    22201 gacaagactg taagctcgaa aaaatgaaaa aaatgcgagt ttctaacatt ttatgttata
    22261 aaacataaca tgtataataa gataaaaaag tggcgaaagt atgttcggtg tggtataatt
    22321 ttttagtaag gaatgccttt gctttccttt tctttttatt ggtcgtaaaa tgaaaaggaa
    22381 tgaatgaaaa ggaggacgaa gaatgattga gagagatacc tcccgacact ttgagcttgt
    22441 ctcgaaatac caaccggctg gtgatcagcc tgaagcgatt aaccaattag tggatggcgt
    22501 agtcggcggg aaaaaagcac aaatcttatt aggtgcgact ggaacaggga aaacatatac
    22561 gatttccaat cttattgaga aagtgaataa accaacactg attattgccc ataacaaaac
    22621 attggctggt cagctgtacg gggaattcaa ggaatttttc cctaacaatg ctgttgaata
    22681 ttttgtttct tattatgatt attatcagcc tgaagcttat gtgccttcaa gcgatacgta
    22741 tatcgaaaaa gattcaagtg taaatgatga gatcgacaaa ttacgacatt cggctactag
    22801 ttcattatta gaaagaaatg atgtgatcgt cattgcatcc gtttcatgta tttttggatt
    22861 aggctcgcct tttgagtacc aaaaacaagt agtttcgatt cgacagggag cagaactaga
    22921 tcgcaatcag ttgattcgtg acttagtcag tatccaattc gaaagaaatg atatagattt
    22981 tcagcgcggt cgttttcgag tgcgcggtga tgtcgtggag atttttccgg cttcaagaga
    23041 tgaacgtgcc ttacgtgtgg agttttttgg agatgaggtc gaacgtatcc gagaagtcaa
    23101 tgcactgaca ggtgaagttt taggagaaac ggaacacgta gcaatcttcc cggcgactca
    23161 ctttgtgacg aatgatgaac atatggagca tgccgtagcg aatatcaaag cggaattaga
    23221 acagcgttta actgtcttgc gaaatgaaaa caaacttctg gaagctcaac gtttagaaca
    23281 gcgaaccaat tacgatattg aaatgatgtt agaaatgggc tacacgtcgg gaattgaaaa
    23341 ttattctcgg catatggacg gacgtaaaga aggtgaaccg ccttatacgc tattggattt
    23401 ctttcctgaa gattttttga tcgtggcgga cgaatcgcac gtaaccatgc ctcaaatcag
    23461 aggaatgtat aatggtgacc gagcgagaaa acagatgcta gtagattacg gtttccgttt
    23521 gccatctgct ttagacaatc ggccacttcg gttagaagag tttgaaaaac atgtcaatca
    23581 gatcatttat gtctctgcga cgccaggacc atatgaacat gaacaaacag ataccgttat
    23641 ccaacaaatc atccgtccga cagggctgct tgacccagtg atcgaagttc gtccaatcat
    23701 gggacaaatc gatgatctag taggcgaaat aaatgaacga gtcgaaaaag accagcgggt
    23761 gtttgtaacg acattgacga aaaaaatggc agaagacctc acagattatt tcaaagaatt
    23821 agggatcaaa gtcaaatatt tgcatagtga tatcaaaacg ctggaacgaa cagaaatcat
    23881 tcgagatctt cgattaggtg aatttgatgt gttagttgga atcaatttgc ttcgtgaagg
    23941 attagacgta cctgaagttt cccttgttgc tatcttggat gcggataaag aaggcttttt
    24001 acgtagtgaa cgttccttag tccaaacgat tggacgagct gctcggaatg aagaaggtaa
    24061 agtaatcatg tacgcagaca aagtaacaga ttctatgcgt ctagcgatgg atgaaacgtc
    24121 aagacgtcgt acgattcagc agaagtacaa tgaagaacat gggatcgttc caaaaacgat
    24181 cattaaagaa atccgagatt tgatttctat tacgaaagaa tcggaagatg atacaaaaga
    24241 agcggtacaa gtctcgtacg aagaaatgac gaaggaagaa aaagacacgt tattgatgaa
    24301 attagaaaaa gaaatgaaag atgcggcaaa agctttggat tttgaaacag ccgcgaatgt
    24361 gcgagatatg attttagaat taaaagcttc aaagtaggag gacaacatgg ctaacgataa
    24421 aattacgatt catggtgcac gtgcccataa cttgaaaaat atagatgtaa cgattccacg
    24481 agataaattc gtggtcgtta caggtttgtc cggttctgga aaaagttccc tagcatttga
    24541 tacgctgtac gctgaagggc agcggagata cgtagagagc ctttctgctt atgctcgtca
    24601 gtttttagga caaatggata agccggacgt agatagcatc gacggattga gtccggcgat
    24661 ttctattgat cagaaaacaa caagtaaaaa tcctcggtcg acagtaggta ctgtgacgga
    24721 aatcaatgac tatttacgct tgttgtttgc acgtgtagga catccgattt gtcccaacga
    24781 tcatatcgag attaccagtc aatcagtaga tcaaatggca gatcaagtaa tggctttgcc
    24841 tgagcgcaca aagatccaag tgttggcacc gatcgtggta aagaaaaaag gacaacataa
    24901 aaaaatattc gaacgaatcc aaaaagaggg atacgtccgc gttcgagtcg atggtgagat
    24961 ctatgattta agtgaagtgc ctgagctgga gaaaaacaaa aaacatgata tcgcgatcgt
    25021 catcgaccgg atcattgtga aagaagggat tcgttctcgc ctatttgatt ctttagaggc
    25081 ggccctgcga ttagcagacg gctatgctct ggttgacgtg atcggtgaag aagaaatgtt
    25141 gtttagcgaa cactatgcct gtccttattg cggatttact gttggcgaac tagaaccaag
    25201 actgttctca ttcaatgcgc cttttggagc ttgtccagac tgtgatggtt taggtgtcaa
    25261 attagaagtc gatcaagatt tagtgattcc agatagaacg aagacactta gtcaaggtgc
    25321 tatcgttcca tggaatccaa tcagctctca gtattatcct caaatgttag cgcaggcttg
    25381 tgaaagtttc ggtatcgatt tagatacacc attcgaagaa ttaccggaag agcatcagga
    25441 gatcatcttg aatgggacag atgatctttt ccatttccat tatgaaaatg attttggtgg
    25501 cgttcgcgat gtagaaacga ctttcgaagg ggtattgaag aatatcgagc gtcgttatca
    25561 tgatacgaac agtgatttca cgcgtgagca aatgcgtctt tatatgacag aattaacttg
    25621 tcagacatgt aaaggttatc gattgaatcc ccaagctcta tctgttcaaa tcaatggaac
    25681 gaatatcggg caaacaaatg agttgtctat tcaaaaagca gtagatttct tctcaaactt
    25741 aacgttatct gaacaagaga aagtaattgc caaaccgatt ttaaaagaag taaatgacag
    25801 actttcattc ttggaaaatg tgggactaga ctatctaact ttgagtcgcg cttccggaac
    25861 attatctggg ggagaagcgc agcgaatcag attggctaca caaattggat cgaatctttc
    25921 tggagttttg tatattttag atgaaccatc gatcggattg catcaacgcg acaacgatcg
    25981 actgattggc tcattaaaga aaatgcgtga tcttggcaac accctcgttg tagtcgaaca
    26041 tgatgaagat acgatgtggg cagcagatta tttgattgac gtcggacctg gggccggaga
    26101 acaaggcgga caaatcgtgg ctgcaggcac tcctgaagaa gtagctaatg atgaaaattc
    26161 tttgacaggg aaatatcttt cagggaaaaa atcaatccct gtaccaaaag aacgccgtaa
    26221 aggtaatggg aaagcaatca agatcactgg tgcttcagaa aacaatctga aaaatattag
    26281 tgttgaattt ccattaggag aatttgtagc agtcacaggt gtgtctggtt ctggaaagag
    26341 tacattggtc aatagtatct taaagaaatc gttagcgcaa aaattaaata agaattctgc
    26401 taagccaggt aaattcaaga caatttccgg ctacgaaagt atcgaaaaga tcatcgatat
    26461 cgatcaaagc ccaatcggcc ggacgccgag aagtaatcca gcgacttata caagtgtatt
    26521 tgatgatatc cgtgggttat ttgctcaaac gaacgaggca aaaatgcggg gttataagaa
    26581 agggcgtttt agtttcaacg taaaaggcgg tcgttgtgaa gcttgtcgcg gggatggaat
    26641 tattaagatc gaaatgcact ttttgcctga tgtctatgtt ccttgtgaag tatgtcatgg
    26701 taaacgatat aattctgaaa cattagaagt gcattacaaa ggaaaaagca ttgctgatat
    26761 tttggaaatg acagtagagg atgctgtaga attcttcaag cacattccaa agattcatcg
    26821 caaactgcaa acgattgttg atgttggctt aggttatgtg acgatggggc aaccagcaac
    26881 gacattgtcc ggtggtgagg cacaacggat gaaacttgcc agtgaattgc acaaaatctc
    26941 taatggaaag aatttctata tactagatga accaacgaca ggacttcata gcgatgacat
    27001 cgcccgcttg ttgcatgtat tacaaagatt agtagatgct ggtaacacag ttttagtgat
    27061 tgaacacaat ctagatgtaa tcaaaacagc agattatatc attgatttag gaccagaagg
    27121 tggagaaggt ggaggaacga tccttgcgac tggaacacca gaagaaatca ttaacgtaaa
    27181 agaaagttat acaggtcact atttgaaaaa aataatggta taaagaggat agatagctga
    27241 gatagttaaa aaaacataaa aaaatgaatt tttgcttgtt ttattaatat cagtgttcta
    27301 gaatcattac atggtagttc tttctacact gattggtata gataaaaact tcctataagt
    27361 tcaatccgtt caaaaaagaa ttgagcaatc ggaggacttt cctttgattg cttttttctt
    27421 tatggtatga tattccttgt gtagttggaa aagaaaaaca agagattatg agtaagtgag
    27481 agataatgat gaacagtatt gaaaatgaag aatttatccc tatattatta ggaagcgaca
    27541 tgaacgttta tggtatggca cgttctttta atgaagcata cggcaaaatc tgccaagcat
    27601 atgcttcgga tcagttagcc cctacccgct acagtaaaat tgtcaatgta gaagttattc
    27661 caggatttga taaagaccct gtatttatcg agacgatgct tcgtttggca aaagaaagat
    27721 attctgataa gagtaaaaaa tatcttttga ttgcttgtgg tgatggatat gcagaattga
    27781 tctcccaaca taaacaagag ctgtcagaat attttatctg tccatatatt gattattctt
    27841 tatttgaaag gctgatcaat aaagtaagct tttatgaagt ttgtgaagaa tatgatcttc
    27901 cgtatcctaa aacattgatc gtcagagaag aaatgttagt aaatggacat ttggaacagg
    27961 aattgccttt tgaattccca gttgctttga aacctgcaaa cagtgtggag tatctttctg
    28021 tccaatttga aggaagaaaa aaagctttta ttttagagac tagagaagag ttcgatttaa
    28081 ttttaggccg gatatacgaa gccggttata aaagtgaaat gattgtacaa gattttatcc
    28141 cgggtgatga tagtaatatg cgtgtgctaa atgcgtatgt agatgaagat catcaagttc
    28201 ggatgatgtg ccttggtcat ccactattag aagatcctac accagcatcg attggtaatt
    28261 acgttgtgat catgccagat tataacgaaa aaatctatca aaccattaag gcatttttgg
    28321 aaaaaatcga atatacaggc tttgccaatt tcgatatgaa gtatgatcct agagatggag
    28381 aatataaatt atttgaaatc aatttgagac aaggtcgtag cagtttcttt gtgacattga
    28441 acggcttgaa tctggctcgt tttgtcacag aagatcgagt gttcaacaaa ccctttgttg
    28501 aaacgaccta tggaacgaat caatcagata aagcaagatt atggatgggt gtgcccaaaa
    28561 aaatcttttt agaatatgct cgggaaaatg aagacaaaaa actagctgag caaatgatca
    28621 aagaaaatcg ttacggtact actgtatttt atgaaaaaga ccgatcaatc aagcgctggt
    28681 tgttgatgaa atatatgttc cataactata ttccaagatt caaaaagtat tttcatgtga
    28741 aagaaggcta gttcatggag aattttttca gtattttagg cggaatgggc acgatggcga
    28801 cagaaagttt tgttcgcttg atcaaccacc gaacgaaagc tacaaaagat caagaatatt
    28861 tgaattatgt cttattcaat catgcaacag ttcctgatcg tacagcttat attttagatc
    28921 gatcagaaga aaatccaatg ccgtttctgc tggatgatat tgagaaacaa aatttattgc
    28981 gaccaaactt cattgtgttg acttgtaaca ccgcacacta cttttttgaa gagttacaag
    29041 cggcaacgga tattcctatc ttgcatatgc caagagaagc agcaaatgaa cttgtccgtc
    29101 agcatacgac agggagagta gcgattctag gaacagaagg aagtatgaaa gctggaatct
    29161 atgaacgcga agtcaaaaat cttggtttcg aaacagtgat tcctgatact gcgcttcaag
    29221 aaaaaatcaa ttacctgatc tatcatgaga tcaaggaatc ggattatttg aatcaagagc
    29281 tctattacga aatcttagag gaagcggtag agcgcctaaa ctgtgaaaaa gtcatcctag
    29341 gttgcacaga attatctttg atgcatgaat ttgctgaaga taatcattac ccagtgatcg
    29401 atgctcaatc tattttagcg gatcgaacga tcgaacgtgc attagctgaa agaagcgagg
    29461 cattggatac agcatcggaa aagtaaaaaa attggatttg gggcaaatat cctaaaagat
    29521 atttggtcca aatctttttg taaaagaaaa agaaaactgg taatgatacg cccgggatga
    29581 tataatttta ttatgcacaa tgtgagaggg gttcgtaaat atgacagata atttgcaatt
    29641 agtcatcata acaggtatga gtggtgcagg gaaaacagta gctatccaaa gttttgaaga
    29701 tatgggctat ttttgtatcg ataatatgcc gcctcgattg attccaaaat tctgggaatt
    29761 gatcaaagaa tcaggtaaag tcacaaaaat ggctttagga gtggatttgc gttctcgttc
    29821 cttctttgaa gaaatccaaa acatgctgat cgaaatcgaa aatacgaact tcatcgacac
    29881 ttctatctta tttttagatg cttcagacga agaactagtg gctcgctaca aagaaacaag
    29941 acgagcacat ccaatggcga tggacggttt gatcactgaa gggatacgta aagaacgggc
    30001 gatactagac gacttgaaag cccaagcttc cgtgatcatt gatacgacaa cattgacacc
    30061 acgacaatta cgtgaaaaaa tcaatgagtc attcaaatca aagggagacc aaggatttcg
    30121 gatcgaattt gtatcatttg gttttaaata cgggttgccg atcgattcgg atattgtgat
    30181 ggatgtgcgt tttttgccca accctcatta tatcccggaa ctaagaccat tgaccggaaa
    30241 agatcagcca gtctatgatt atgtgatgtc ctttgatgaa acgcaatcat tctaccataa
    30301 atttttggat cttctggaaa ctgtattgcc tggatacatt aaagaaggaa aaagcagctt
    30361 gacagttgca atcggctgta caggcggtca acaccgttct gtggcattga ctgaacgttt
    30421 ggcaaatgct ttagggaaaa actataaagt caatgtgaca catcgggaca aggataaaag
    30481 gaaagagacg gtgaaccggt cgtgaaaatg aaaacctacc ggataagaaa accaaagatc
    30541 gtagtggtcg gcggtggcac tggtctgcca gttatcctga aaagtttacg aaatcaagga
    30601 gcagatatca cagcagtagt gactgttgca gatgatggtg gaagcagcgg tgcaatcaga
    30661 gaatcgatcg ctatggctcc tcctggtgac ttgagaaatg tcttagtggc gttatcggat
    30721 atgccacaat tctatgaaga tattttccaa taccgtttca aaaaggaaga tcagttttta
    30781 gccaatcata cgatcggtaa tctgatcatt gccgcagttt ccgagatgcg gggaagcact
    30841 tatgaggcga ttcaattatt agcaaaaatg atgcatgtag atggacatgt ttatccttct
    30901 tcagaaactc ctttgacctt gcatgctgtt tttaaagacg gaacgactgc agtaggagaa
    30961 tctaaaatcg cgatcaaccg taaaaccatt gaccgtgtgt atgtctgcaa cacaaatgat
    31021 aaaagtgaag ccaaagcggc tcgaaaagtc gtttcagcaa ttatggacgc cgacatggtc
    31081 gttttgggac ccggaagttt attcaccagt atccttccaa atttagtgat accagaaatc
    31141 ggcgaagcaa tgctcaagac aactgctgaa accgtctata tctgtaatat catgacccaa
    31201 aaaggggaaa cggaacattt cacagatgcc gatcatatac gtgttttaca caagcatttg
    31261 aatcagcctt ttatcgatac agtattggtc aatacggaaa aagtgcctga agattatatg
    31321 gacccagaga tctatgatga gtatctagta caagtcgcac acgacttcaa cggattgaga
    31381 aatgaaggat gtcgagtgat ttccaccgac tttttagaat tgaaagatgg tggtgtcttc
    31441 cacgatggag acaaagtagt agaagaattg ttccgtttag ttttcggttc aaaatattaa
    31501 gcaatttatt gttggagaaa ggaggagaat aggatgtcat ttgctgcaga tgtgaagaaa
    31561 gaactaactg gtttggaagt tcatcgagaa catgcgaaag cggaattagc tgctttgctg
    31621 cgaatgaacg gctctttagg tattgtgaac cagcagttta ttttgaacgt ccaaacagaa
    31681 aatgctgcaa ttgccagacg tatctattct cttttgaaag atcattatca ggtacgaagt
    31741 gagctactcg ttcgtaaaaa aatgaaatta aaaaagaaca atgtctatat cgtccggttg
    31801 aagcaaggca caaaagatgt gttgatggat cttgatatca tggatggtat gatgttcaat
    31861 ggacacgttt cggacgagat tatgggaaat tcgcaaaaaa tgcgttctta cttacgtggt
    31921 gcttttatgg cctcaggttc agtcaataat ccggaaacga gtcgttatca tttggaaata
    31981 ttttctattt atgaacagca taaccaagac atttgcgata tgttaaatta ttacggtcta
    32041 catgctcgaa cgcttgaacg gcgcaatggc tatatttcgt atttaaaagg agcagaaaaa
    32101 attgctgatt tcttaacatt gattggtgca accaactcaa tgctccgatt tgaagatgtt
    32161 cgaatcgtac gggatatgag aaattcggtc aatcgtctag tcaattgtga gacagcaaat
    32221 ctgaacaaga cgattgatgc ggcttctaaa caaatcgaaa acatcgaatt gatcgaagca
    32281 aaggtcggtc tacatgccct tcctgaaaaa cttcaggaaa tcgcagaact tcggcttcaa
    32341 catccagagg tcagcttgaa agaattaggg gaaatgattc cctcaggtgc aatatcaaaa
    32401 tcgggaatta atcaccgaat tcgcaaaata aatgaatttg cggaaaaact gcgtgaagaa
    32461 gcagtttaat ccaaagaaaa aactgataca tgaagcagga gatgcgaatg tatcagtttt
    32521 ttttaaaagc tatacttgct tttcttccgt caaactataa ttccaacttt actggagtaa
    32581 cataatgttg aaaggcttct attgtttttt aatacaatcg tataaaaagc ggggagacaa
    32641 ctgaatgaag attttagttt tatacataaa cttttgctta atatagaagt cctgatatag
    32701 ataggatcaa gtatttatct ataactggag attaattaaa aactggaagg aactgctcga
    32761 tcaaccttga gaactgtttt tcttacttct ggtcaagatt ctcgtggttg gtggataagg
    32821 atggttgata agttcattgg attagctagt cgaaaacaac caggtgtaat taatgtagaa
    32881 gttttaacaa ggggatggag tgatttattc agtgataatc ataagttcat aaatagtaat
    32941 tgggatgtat ggttggtata cgttatacct gaacttgaac tatcaagatt tggtttagaa
    33001 tttgagaatc gatgtttata aagggagggc aaaaaatgtg cttttttaca acttttacta
    33061 tcattatgat tgcagtactt tttatttttc tagatatagc aaagcgaaat acagcatttt
    33121 tattatatcg ggttttactt cgagcaggtc tcataacatt tatatcgatc gttggatttt
    33181 ttctattcac agttattgta tttatttgga gaactacagc accaccattg ccagagatta
    33241 catatggaga atttccgttt agtcttgaat atgaaataga tgaggaaaga attttgattg
    33301 aagatacggt gattgcagaa tttataggaa gttttagagg gaatgtgaca actcaaccta
    33361 gacgaagttg gagtataaaa cttttaaata atagtggaga gttgaaagca tttcattatg
    33421 aattcttaat aatagaaagt gaagatgtaa caatcacttt aagtagtggc tctgctggat
    33481 attttatgaa tgatggtgga agcaagccac agctcacagt ccgtgatcgt attgcaggtt
    33541 ttatgcattt ttctcactat gacttagaag aagctcgtaa aatacttgca gaatatggga
    33601 tcacattaat caattgggaa tatgcgccac cgataagaaa ttttttcaat gattattatt
    33661 agtcttataa aaaacagaat gtaaaattta tgtgcgcgag tatttagttt tccatttttt
    33721 gtttgataga tatatagcat tgttgaagca tgggatagtg gtgccaattt tatcaatgag
    33781 gttggtcagg cagttaacat aattggtgat gctataaatc catttaattg gaattggagg
    33841 aattaggtgt ggaaacagtg agattatgga tattcatgaa aaattttcgt tcggctttga
    33901 gatatgttat tctggaatca aaatcaggtt attatctgat tgacacagat cactatactt
    33961 tttggggagg ctaccttttt ccgattttta attggataat cccccataag gttatgaaaa
    34021 ttaacttgcc tgcagaagaa ataaatagat taatactcaa caaagattta caaaggaaaa
    34081 gagagaaaga acattctaat gttgcttgga taggtccagc atttgcagta gtgacttctt
    34141 caattgtcgg tcctatgcta gagagtattt atagtgattt ttctattgga atacgttatt
    34201 tatttgttac tttaagtata gctgttcttt tgtgcataaa gggttatgtt agcaagaaga
    34261 ataaagatat tttaacacta atcggtgtaa acaatttatc tagtactaaa attatactgt
    34321 ttcctgaatc tataaaagaa ggatcaaggt tgttgataat ttttataatg cttatactgt
    34381 tttctgtttt atttggggtg atgtttatag
//
LOCUS       DAIGWC010000026        33263 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.026, whole genome shotgun sequence.
ACCESSION   DAIGWC010000026 DAIGWC010000000
VERSION     DAIGWC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.026"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(41..229)
                     /locus_tag="NOB74_001226"
     CDS             complement(41..229)
                     /locus_tag="NOB74_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HCI1220425.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="NOB74_001227"
     CDS             499..861
                     /locus_tag="NOB74_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI1220426.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="NOB74_001228"
     CDS             913..2595
                     /locus_tag="NOB74_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HCI1220427.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="NOB74_001229"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="NOB74_001229"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HCI1220428.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="NOB74_001230"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="NOB74_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HCI1220429.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="NOB74_001231"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="NOB74_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCI1220430.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="NOB74_001232"
     CDS             6430..7434
                     /locus_tag="NOB74_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220431.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="NOB74_001233"
     CDS             7435..8379
                     /locus_tag="NOB74_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220432.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /locus_tag="NOB74_001234"
     CDS             8379..9341
                     /locus_tag="NOB74_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220433.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="NOB74_001235"
     CDS             9368..10282
                     /locus_tag="NOB74_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220434.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="NOB74_001236"
     CDS             10308..12089
                     /locus_tag="NOB74_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1220435.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /locus_tag="NOB74_001237"
     CDS             12437..13123
                     /locus_tag="NOB74_001237"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HCI1220436.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="NOB74_001238"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="NOB74_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HCI1220437.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="NOB74_001239"
     CDS             16733..17542
                     /locus_tag="NOB74_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1220438.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="NOB74_001240"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="NOB74_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HCI1220439.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="NOB74_001241"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="NOB74_001241"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HCI1220440.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="NOB74_001242"
     CDS             complement(21094..21546)
                     /locus_tag="NOB74_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HCI1220441.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="NOB74_001243"
     CDS             21696..22646
                     /locus_tag="NOB74_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCI1220442.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="NOB74_001244"
     CDS             22639..23598
                     /locus_tag="NOB74_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCI1220443.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="NOB74_001245"
     CDS             23595..24350
                     /locus_tag="NOB74_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1220444.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="NOB74_001246"
     CDS             24373..25326
                     /locus_tag="NOB74_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1220445.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="NOB74_001247"
     CDS             complement(25970..26266)
                     /locus_tag="NOB74_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HCI1220446.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="NOB74_001248"
     CDS             26621..26977
                     /locus_tag="NOB74_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI1220447.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="NOB74_001249"
     CDS             26987..27886
                     /locus_tag="NOB74_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HCI1220448.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28403..29134
                     /locus_tag="NOB74_001250"
     CDS             28403..29134
                     /locus_tag="NOB74_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI1220449.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="NOB74_001251"
     CDS             29279..31306
                     /locus_tag="NOB74_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HCI1220450.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="NOB74_001252"
     CDS             31414..32511
                     /locus_tag="NOB74_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI1220451.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32818..>33263
                     /locus_tag="NOB74_001253"
     CDS             32818..>33263
                     /locus_tag="NOB74_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220452.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11138 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagcatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttttat tattgtagga tggttgggct ctttttataa caatataaaa
    32581 tataccattt tattaataaa aatgcatact agtaaatgat ataattctaa taacaggttt
    32641 gatcgcgaga aaggccaaat aaaacgctct ccaaaatgtt aaaaaaaaga caggacgatg
    32701 tatattatac aaacaagaat cgctgacaac agtgactcgg atccaggaaa tcagttttat
    32761 ccccagctag ttggtgaatg catggaaagt aatatacgta gaaagagctg atgactaatg
    32821 aattatgagt tttttttaag caaagaagat cacagaagtt attcattact taaatattta
    32881 gaagcaagct caaatttatc agagtcaata tcgaatgttc aagaagagtt gtcgctatcg
    32941 acatttctct tgaaaaaaac gatcgataag ctgaaacatg atttacaaaa gttcgatcta
    33001 gagaaaaatt tgcgagtaac cgtcagtgaa ttggatatat gtctggaaat taatggaaaa
    33061 tgttctagca aagctctgtt atctcgttat ataacggatt ctttatctat gaaaatggta
    33121 ttggctttct ttcaggaaaa atatatctca gtagaaaatt ttgctaaaca gcatcacgtg
    33181 agttattctg tggcttataa agtattacaa agactaaaaa gaaatctaaa aaaatatcaa
    33241 attttttttg aaaagagaaa gtt
//
LOCUS       DAIGWC010000027        32685 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.027, whole genome shotgun sequence.
ACCESSION   DAIGWC010000027 DAIGWC010000000
VERSION     DAIGWC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.027"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(41..1180)
                     /locus_tag="NOB74_001254"
     CDS             complement(41..1180)
                     /locus_tag="NOB74_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1220453.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(1294..1878)
                     /locus_tag="NOB74_001255"
     CDS             complement(1294..1878)
                     /locus_tag="NOB74_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HCI1220454.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(2005..2436)
                     /locus_tag="NOB74_001256"
     CDS             complement(2005..2436)
                     /locus_tag="NOB74_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCI1220455.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFTASHFEYSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(2454..2774)
                     /locus_tag="NOB74_001257"
     CDS             complement(2454..2774)
                     /locus_tag="NOB74_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1220456.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            3068..3208
                     /locus_tag="NOB74_001258"
     CDS             3068..3208
                     /locus_tag="NOB74_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220457.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            complement(3205..3384)
                     /locus_tag="NOB74_001259"
     CDS             complement(3205..3384)
                     /locus_tag="NOB74_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220458.1"
                     /translation="MNKKTDEIAADLVVAWLNHESQVSTKGESISPKEIAQAYLDIHY
                     AVIYGQLPEDRKNDD"
     gene            3465..4211
                     /locus_tag="NOB74_001260"
     CDS             3465..4211
                     /locus_tag="NOB74_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HCI1220459.1"
                     /translation="MNTPQIFSFEQHEVRTFLENDIPYFVANDVAKTLGYKNPSKATN
                     DHCKKSIETWGNDSLGRRQKFKVIPESDVYRLIIKSNLPSAEKFEAWVMEEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            4226..4429
                     /locus_tag="NOB74_001261"
     CDS             4226..4429
                     /locus_tag="NOB74_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220460.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            4445..4783
                     /locus_tag="NOB74_001262"
     CDS             4445..4783
                     /locus_tag="NOB74_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HCI1220461.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            4770..4949
                     /locus_tag="NOB74_001263"
     CDS             4770..4949
                     /locus_tag="NOB74_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220462.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(4992..5462)
                     /locus_tag="NOB74_001264"
     CDS             complement(4992..5462)
                     /locus_tag="NOB74_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220463.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            5549..6247
                     /locus_tag="NOB74_001265"
     CDS             5549..6247
                     /locus_tag="NOB74_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HCI1220464.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            6425..6766
                     /locus_tag="NOB74_001266"
     CDS             6425..6766
                     /locus_tag="NOB74_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220465.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            6759..7430
                     /locus_tag="NOB74_001267"
     CDS             6759..7430
                     /locus_tag="NOB74_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HCI1220466.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            7436..8122
                     /locus_tag="NOB74_001268"
     CDS             7436..8122
                     /locus_tag="NOB74_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220467.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            8125..8955
                     /locus_tag="NOB74_001269"
     CDS             8125..8955
                     /locus_tag="NOB74_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HCI1220468.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            8972..9823
                     /locus_tag="NOB74_001270"
     CDS             8972..9823
                     /locus_tag="NOB74_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI1220469.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNTELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            9820..10179
                     /locus_tag="NOB74_001271"
     CDS             9820..10179
                     /locus_tag="NOB74_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HCI1220470.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANDWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            10194..10355
                     /locus_tag="NOB74_001272"
     CDS             10194..10355
                     /locus_tag="NOB74_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCI1220471.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            10352..10657
                     /locus_tag="NOB74_001273"
     CDS             10352..10657
                     /locus_tag="NOB74_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220472.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKTR
                     RRMPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            10657..10974
                     /locus_tag="NOB74_001274"
     CDS             10657..10974
                     /locus_tag="NOB74_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HCI1220473.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     GSK"
     gene            10971..11357
                     /locus_tag="NOB74_001275"
     CDS             10971..11357
                     /locus_tag="NOB74_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220474.1"
                     /translation="MIPRFRSWYTPFKGKTIGQEMKYGQAGRLITHAEMAPDKYVLMQ
                     STGLKDKNGVEIFEGDVVLVNVSNGFDHLVNEKTVVQESEFHSGLVCKSLISGMEYRI
                     FSHQKMGYEYEVTGNIHENSELLEVE"
     gene            11354..11689
                     /locus_tag="NOB74_001276"
     CDS             11354..11689
                     /locus_tag="NOB74_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220475.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDIHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEQ"
     gene            11835..12404
                     /locus_tag="NOB74_001277"
     CDS             11835..12404
                     /locus_tag="NOB74_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HCI1220476.1"
                     /translation="MNKQEAIKKLESIKVIGNDALAACYNESINAGITLMKKIDEPKK
                     LVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLYSVIIAGEYLVKEISCSNEVKLVSTAYLPQYLAH
                     HYQLTEKQIKAIDERYWPFAVPVEEVAEG"
     gene            12401..12574
                     /locus_tag="NOB74_001278"
     CDS             12401..12574
                     /locus_tag="NOB74_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220477.1"
                     /translation="MSRQIMLHIPDGTKAMTITIVAAQKDGGLALKTKSIDTKQILEG
                     RDVEIEIDEEEAE"
     gene            12571..12876
                     /locus_tag="NOB74_001279"
     CDS             12571..12876
                     /locus_tag="NOB74_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220478.1"
                     /translation="MNVQVYLKRDLARFPRSWDTNSHPSEAEEEGYLMSANMIEITRD
                     DADEFDKKRSWYSVPNPMYTAVIEDYHISDRFILIDLERPKKRIKQYRRCGFSTKKW"
     gene            12900..13097
                     /locus_tag="NOB74_001280"
     CDS             12900..13097
                     /locus_tag="NOB74_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HCI1220479.1"
                     /translation="MNNRHRRVAKLRNQELNVAKVKFEREYGVSAEETYKVASQCVAD
                     ASDAIRKFGISILDIKWEDTE"
     gene            13094..13300
                     /locus_tag="NOB74_001281"
     CDS             13094..13300
                     /locus_tag="NOB74_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220480.1"
                     /translation="MKIYVVKFGNQFYRSDERSIGANTLSIVDILQSARWFDNLEEAN
                     QVSRRLGGLTQVYELVTVDHEGVE"
     gene            13300..13596
                     /locus_tag="NOB74_001282"
     CDS             13300..13596
                     /locus_tag="NOB74_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220481.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFRGYVEKVLSNSAIIRIENTMECDKWLAKSKENLAVARLVDMEVIESK"
     gene            13672..14085
                     /locus_tag="NOB74_001283"
     CDS             13672..14085
                     /locus_tag="NOB74_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HCI1220482.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            14769..14936
                     /locus_tag="NOB74_001284"
     CDS             14769..14936
                     /locus_tag="NOB74_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220483.1"
                     /translation="MYRPQYLEQKYEVITVQNGNGEIVRKYRRPIKSDTYKRKESNEV
                     IPLYGKRIAKH"
     gene            14962..15306
                     /locus_tag="NOB74_001285"
     CDS             14962..15306
                     /locus_tag="NOB74_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCI1220484.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            15311..15592
                     /locus_tag="NOB74_001286"
     CDS             15311..15592
                     /locus_tag="NOB74_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220485.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVDIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNIFGYSIEEINYYIDFAEAFIPMVR"
     gene            15695..16009
                     /locus_tag="NOB74_001287"
     CDS             15695..16009
                     /locus_tag="NOB74_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HCI1220486.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            15987..17681
                     /locus_tag="NOB74_001288"
     CDS             15987..17681
                     /locus_tag="NOB74_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCI1220487.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYNIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            17701..18879
                     /locus_tag="NOB74_001289"
     CDS             17701..18879
                     /locus_tag="NOB74_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI1220488.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            18842..19528
                     /locus_tag="NOB74_001290"
     CDS             18842..19528
                     /locus_tag="NOB74_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HCI1220489.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            19528..20688
                     /locus_tag="NOB74_001291"
     CDS             19528..20688
                     /locus_tag="NOB74_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCI1220490.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKEAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YRFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            20698..21573
                     /locus_tag="NOB74_001292"
     CDS             20698..21573
                     /locus_tag="NOB74_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220491.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNTGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            21570..21881
                     /locus_tag="NOB74_001293"
     CDS             21570..21881
                     /locus_tag="NOB74_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220492.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            21871..22224
                     /locus_tag="NOB74_001294"
     CDS             21871..22224
                     /locus_tag="NOB74_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HCI1220493.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            22214..22615
                     /locus_tag="NOB74_001295"
     CDS             22214..22615
                     /locus_tag="NOB74_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220494.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            22608..23012
                     /locus_tag="NOB74_001296"
     CDS             22608..23012
                     /locus_tag="NOB74_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220495.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            23024..23629
                     /locus_tag="NOB74_001297"
     CDS             23024..23629
                     /locus_tag="NOB74_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI1220496.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            23649..24011
                     /locus_tag="NOB74_001298"
     CDS             23649..24011
                     /locus_tag="NOB74_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220497.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            24213..27644
                     /locus_tag="NOB74_001299"
     CDS             24213..27644
                     /locus_tag="NOB74_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCI1220498.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFSDLWKKFTDWLGDTWESIKESASSVWDGVKET
                     WSGFVDWVQEIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            27695..28432
                     /locus_tag="NOB74_001300"
     CDS             27695..28432
                     /locus_tag="NOB74_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI1220499.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            28442..30733
                     /locus_tag="NOB74_001301"
     CDS             28442..30733
                     /locus_tag="NOB74_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI1220500.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYDTAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYINDGDGNSLGIDGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDVDHFIIETSKPNVLVRWNLVAHRL
                     GYEDVRLKEDTAYDSTVLDQKRF"
     gene            30757..>32685
                     /locus_tag="NOB74_001302"
     CDS             30757..>32685
                     /locus_tag="NOB74_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220501.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDDQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFLAEIKGRMDSLNKQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLHVMYSNSIDFGGYDYSGNPNLMSKLKSSDFN
                     VGYHGSLTNVNGMLHFMSDGTGDIDMFTRINTPQLASGKTYTLSAKVRFDEGTTGAIN
                     KLRLVYRTSPGENILLEANNTTITIDDVGKEITIKGTANVNYQITNLDRFYISVSFSN
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWVGKTSLGKNIANKGTTFPIKSSAY
                     EIYKGNTEEELIIGQTYTITLKGTKPASQTFVAYNYWNVNFGDLKPVEGLTDVWSLTF
                     TPTKLEPGLPKDLRIFQSPKETAGACRIDWLKIEKGDTRTPNIEQYKYRGIGMRDSNN
                     PKDYVWDLEPSYVENNLATDIKVAEITGKANNYTDGKVSEINSQLTASINEVDTTAKD
                     AQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALN
                     GKSSGGNDSTILTIPEGYR"
BASE COUNT        11587 a         4968 c         6724 g         9406 t
ORIGIN      
        1 acaggggttt gttttgtatt tgtgccaaaa atgtgccaaa ctagttatca tttttatata
       61 aactatcgaa cacagtattg attttttctt tatcctgatc ttcaagctct cgaacaatat
      121 gaagataagt agacattgta gtttctaaac tgctatgtcc taaacgtttc gatacgctaa
      181 gtatatttac tccttgataa agtaaaatag atgcatgtgt atgccttagt ccatgcaaag
      241 taaattgctt ttcaatccct aattctttta attttttgcg caaatatttg ctgacggcgt
      301 ttgatgaaac taatccattt tttaagttga aaaaaacaaa attatgaggg tttttgattt
      361 caaaattctc gaataattct ttttgattga ttttaaactt ttttaagaga tcaatcgtat
      421 gtttatcaat ggaaattttc ctatttgaag tttcgttttt tgtttttccc cattcattta
      481 atttataatt ccatgtttta ttaatagtga tgatttgatc ttcgaaatcg atatcttccc
      541 atgttaatcc tagaagttca gcaaatcgca ttccagtggc accagcaact aacacgagca
      601 taggagaaga gtactgcgca gaaaggtttt cttctacgag tttcattaaa gatttaaatt
      661 gatcataatc taaatattta tcttcttttg gcttcaatga atcttttcct ttgattactg
      721 cttttctagt tggatcaaac ggaattaatc cttcttctac ggcatctttc aacgacgctc
      781 taatatggtt attaaactta ataacggtag attttacatg gtctttagca tacttattta
      841 aaaagcgttg atatcccact ctatctaaat cagaaatcaa taccgctggc atatatttct
      901 ttatgttcat taacgtatct tcgtattttc tataagtgat aggagatact gttccttctt
      961 tataaagttg catccaatcc tcaaagtaat ctgataataa tagatttttg cgatcccctt
     1021 taaggccttt gttcaagtta tattctaatt cgttggcggc atcttttgct tcgccttttg
     1081 tcttaaatcc tgattttctt atcttcgtgt attttccgtc atcttttttg tatgaaattt
     1141 cgtattgcca actatttcca cgtttgacta atcttgccat aattgaatct actctctttc
     1201 tctgatacaa taggcactat aaagaagcct actgtatagg tttgtttttc ttagaacacg
     1261 cttgctttgg acggtgggcg tgttttttat ttattataca gttgctttaa aaatagctgc
     1321 tttttcaaat gatactaaag gagagaagtg gatttctatt tctccctttt ggtttaacgt
     1381 gaaatgagca gttacatcca tttgttttcc tggagcaaca gatcccattg tattttcgtt
     1441 ggcatatgtc tctgattttt tgtcatctgg tccatatact tccacatctg tacctacagg
     1501 gatatctgaa tcgccatcat tttttacggt ataagtaatt tttactactt gtgcaggttg
     1561 gttttcttca aattgatttc tttcatcagt tagttctaca ctatttagtg tatattcagc
     1621 atcaccaact tttacagtgt caccaatctt atagaaggta tcgctttttt cttctttaga
     1681 agatgaagca gaggttgaag atttagttac tttttcgcca ccattatcac ttgctttatt
     1741 actatctgat ccaccattta aagcagaacc aataattata attaaaatta ctgctaatac
     1801 ccaaaaccat acttttttgt aaaaaggttt actaacttta tacatttttc cgtcttgacc
     1861 cataactttt tttgccattt aaatattcct cacttcttgt tataatatat ttgcgatctc
     1921 agaaatgagg tatgagtccg tgtgccagca cgggcttttt taatgttttg ctgaaatcgg
     1981 tttttttaat aattcttgat gtattcatac atattgcctt gcgtaagaat attttttctt
     2041 aaaatagcat tggcagacag cataacaagt gtatctgagc ttattctgaa tagaataata
     2101 ctccataaat ttttcgagat taaactgaga ttcatcagtc agttcgttct caatatagat
     2161 atttaataaa attagaatag ctattttatc tgcttctgtt tcaaattttg agtgaaaagt
     2221 tgtagaagta tcgtacaaaa ctgaatattc aaaatgagaa gcggtgaaat gcgcaagttc
     2281 atgagataaa tgaaaggctt ctgcagtttc gccatataga ttttcattca aaaaaatgat
     2341 tctaggcttc ggataataga agccaggctc tttcatttcc atgtaaacta ctttcaaatt
     2401 gtattcgctc aacatttctt tcaatttcaa atacatacaa cccatcactc caactattca
     2461 ttttcctcta aagctttagc aattgcaatc gctttacgca ttgtctcctt agatatttct
     2521 tttccatcaa aagaaaaaac agtatcgttt tctgataaat ccacatgttt aggggtttct
     2581 ttttcttcgc gccccagaag atagtctaca gagacatcga aatagtcagc aatttcttgc
     2641 aaacgttctg tagaggggtt tgagttctta agtctatata agacgttttt accatagcct
     2701 aggtcttctt caactttatt taatgatttt ccctgttttt tcgctaactc ttttattctc
     2761 tcaaacgtta tcatatcaat attcctttcg ttcaagaaaa aatatttaac tttatttgtt
     2821 aaaattcgtt gactatttta acaaaaggtg ttaatatcat tcttgtaaac aagtttaaca
     2881 actaaaaaga caacaaaaaa cactatcgat taataaatgc caaccgccaa gaaagctttt
     2941 aaaatcaatg tttatatgtc ttatttaact atgttctgat tttaacactg tatgttaatt
     3001 tagtcaacgc agttttttta aaagttgtta aatttgttta cgaatataaa agaaaggaga
     3061 gaagaatatg gaaaaaacag tctcggcaaa aatcgaagat ttgaaattag acatactgaa
     3121 acaagcaaaa gtggcgatgg aacacgcggt agataaagaa gactctgcca tggttgcagc
     3181 catagcagag attttagctc acgtttagtc atcgttttta cggtcttctg gaagctgacc
     3241 atagataaca gcataatgaa tatctaaata agcttgagca atttcttttg gcgaaattga
     3301 ttcgccttta gtagatactt gtgattcgtg atttagccat gcaacaacta aatccgcagc
     3361 gatttcatca gtttttttat tcatacttat tcaccacctt atgcattatt tcagtagacc
     3421 acttactgat aagaaaatta tatcaaagaa aggaatgaac aaaaatgaac acaccacaaa
     3481 tttttagttt tgaacaacat gaagtaagaa cgtttctaga aaatgacatt ccgtatttcg
     3541 tagcaaacga tgttgccaaa actttgggat acaaaaatcc cagtaaagcc accaatgatc
     3601 attgtaaaaa atcaattgaa acatggggta acgattcgtt aggtcgtcgt caaaaattca
     3661 aagttattcc agaatcagat gtttaccgct tgattattaa atcgaactta ccaagcgctg
     3721 aaaaatttga ggcctgggta atggaagaag tccttccaac aatcagaaaa acaggtagct
     3781 attcaaacgt acctcaaagt tttgcacaag cattgcgttt agcagcagat ttagaagaaa
     3841 agaaccaatt actcgaacaa caaattgccg agtacgaacc aaagattagc tacttagata
     3901 cgattctttc atcgacagat acggtagcta cttctcaaat tgcagctgat tacggaatgt
     3961 cggcaattgc tctaaacaaa ttgctaaacg agttaggtgt tcaacataaa gttagcggac
     4021 aatggatact ttaccgaaaa catatgaacc aaggatacac aaaatcgcac acaagtgaga
     4081 ttccgaaagc cgatggcggc actaaagttg taatgaatac caaatggaca cagaaagggc
     4141 gagtgtttat ttacaactta ttaatcgcag agggctatta ccctcaaatg gatttagagg
     4201 aaattggtta gaaaggagtt ttagtatgac tgacattgca gaaatcactc aacgagatag
     4261 agaaaaaatc aaagaatatg tcgaaagttc gaagttctta acttacacca tgcttgctga
     4321 aagatttgga attagcaaaa gctacttatc tttaatttta aacggtaaaa agacttctgc
     4381 agaagcaaat agaatcatag attcgattat tactatgtac gaattgtaaa gggaggaaca
     4441 gctaatgcaa tatctagaag cgaaaatccc agttccagaa ggctatgtaa ttatctccca
     4501 agtggattat gaggagttaa aaaaagctga tgatactggt agatggatga cgttgccaga
     4561 agtgctagaa cggattaaca gaaaatatga ttggtttact tctagagttt taaagaaccc
     4621 aagatataga aatattatcg atatcgagaa aaacaaaaat ggatttgtct attatccagt
     4681 tgaaggaaga gacacatatc tatttttaag aagtaaaaca cttgaatttt tagaaacaaa
     4741 tttttcggaa atcttaagga ggcaagcgga tgggaaaatt taatagagcg ctagtgttca
     4801 gcgcaccgct aatcatctac gctttaggac tttggggaag caggcaagcg ttgataggaa
     4861 cgattgttta catggtttgg atttttatgg ggcttgatga agctgaagct gagtacagag
     4921 cgaaaaagcc aaccgagggg gctgactaaa aatgaataga aaagagaaac tagaatgtat
     4981 attactatta ctcagtttaa ttctttcact aatttctcta ttgggaagtt tgtatttttg
     5041 atatcaacaa ttttgtggat ttgggttcta tttagagtaa atatcatttt tgtttggtga
     5101 ttaaggagtt tattaaaatt aattttccct acttcaaatg caaggtaaca agatatagca
     5161 cttttaggag gaatatttag cggtacagct tcagagtata ttctattatc atcgactgat
     5221 cctcctttag caattaattt cttaaatgga gtagctgacc atctgcggtt taagttagcg
     5281 gatgaaagtt ctaaattaac taacatagct ggttctgttg aatagttaga aatgattact
     5341 tttgtataaa tcatatctgc agcgaagtaa gaagcattaa gttcaacttc tagttgaggg
     5401 cgcattcctt ttatttttat ccctgttaaa aacgtactca atataaaact tattattgac
     5461 atccattgaa aaattgttaa gtgaaaaaaa ttcaaaataa acaccaccag tttttaacta
     5521 aattatacca aaaaggagag aagaaataat gcaagaatta gtaattttga aaaataaaga
     5581 agctgtgact acgagcttac aagtggcaga aagcttcgag aaaaaacatc aacatgtttt
     5641 aagagatatt gatgcactaa aaaaagatgt gtccaatttt ggacagatgt ttgtagaagg
     5701 taatgaacca gattcatatg gcagaaatcg acgagttttc ttcattagta gagatggatt
     5761 tttcttgctg gctatggggt ttacaggaaa gaaagctatc tacttcaaac aaaaatacat
     5821 tgaagcattc aacgaaatgg aagatgttat tcgcaagaat actgttcctc aaacaattga
     5881 agatatgatg atctatcaat tagaagaaat gaaagatgtt aaaaaagatg tttccatgct
     5941 taaagatact atgcgaatta gcggacaaca agagtttgaa attaagcaaa aaggaaatat
     6001 gaaagttatg ggagttctag ggggaaaaga aagccgagct tatgaagaaa tcagcaaaaa
     6061 agtattctca aaattttggt ctgaatttaa acgtaccttt tcaatcccaa gatatggcga
     6121 gttacctcgt aagagattcg atgatgctgt ttcatttatt gaaatgtggt tgccagaaac
     6181 tgcgatccgt atggaaattg atcaactgaa cagacaacag agactttttg gtgatgacaa
     6241 tgaatagagc tgaagcgcta agaataggga cggcaattgc taattgctgg tggaaatact
     6301 ataaaccaat catcctaagc caacaacata ttgacaagca aaaagcatgg caacaaataa
     6361 aaaagtgact ccgccggcaa gcaaagagtc acaaagaaaa cacatcataa ggagatttta
     6421 gcatatggaa aaagaacttt ccactctaga tcaatatttg attgatcctg attggggcaa
     6481 gccgaaaatt gaggaaacaa gtggtcgaaa aatcagacga aatcttttga cgaatgaaga
     6541 actagcttgg gatcaagatg atttaggcaa ccatgtaact atttgggatc atgtttatct
     6601 tatccatcta tcgaagcatt cgaataaacc tgaatatatt tacgtcatcg aagatggctt
     6661 gattgatgcg ctagaagagt acgacagaga taacttgatt gatatctctt attacggacc
     6721 aggtaagaaa tacattgctg aaatggaggc agaatttgat gagtgaaatc aaagggacaa
     6781 cgaactttga aaaacttttt agtcgtaagt taaataaaat tctcaagaaa aaaggaaatt
     6841 ttgattattt atcttgggct cacgcgtggg agattatgaa aaagaatgat ccacaggcaa
     6901 cggtaactat taatgagtac aaacactaca gggttgtttc tggaactcat caagactttc
     6961 ttgttgagga atataaacct tttcttatgg atgaaactgg gacttatgta tctgtctcag
     7021 taacggttaa aggacacacg gaaaccgaat tatttcctgt tttagattat cgaaaccaac
     7081 cagttgttaa accaaatgca atgcaaatca ataactcatt gaagcgatgc tttgtgaaag
     7141 cattggctct acacggactg ggattatatg tatttcaagg ggaagatatt ccaacaccac
     7201 ctagaatcga tacaaagaaa ttaaacatgc tagagacgat tctagaagct ttcaatgagc
     7261 agatgggtaa agatatgacc aaaaccttaa tcgaatatgt taatgagcag acagataaat
     7321 tagggctctt agctgataac gttgaaacta ttgaacagtt aagctatgag caatgtgcct
     7381 tgatggagcg agcaatagca gctaagagaa aagaattaga taagaagtga tatgagtgtt
     7441 taaaccatta atcgattcat attcagcggt tctgaaaaag ttcaaaggaa aagacataag
     7501 cgcaaccatc aatgaggaag tgaacattga tcgactaaag acgatgtatg acggctacga
     7561 tggtgatcga gtcattgaaa ttcgttttat tgatcctaga cgtttcaccg tacagcaacg
     7621 aaacttcatc tatgcgctga taggcgatat ttttatcgat acaggcatgc caacggactt
     7681 ctggaaggaa ttcttctact ttcgttttga aggtgtcaca gggcgcaaaa taagcctgaa
     7741 agacgaatcg aatacaactg tgagtgatgc caatgtctta gcaaatatca tcttagattt
     7801 catctttgaa catcatattc ctttcaaaga aggctatgag attttacctg cgaatcaaga
     7861 atattacttc tacaaatgca tcacaaaaag agtctgctgc atctgtggca aaacaggagc
     7921 tgacatcgat cactttgaca aagcgctagg aagacgaaag cgcaaagaag ttgatcattc
     7981 agagtacaca tttgcagcac tctgcagaat ccatcacaca gagaaacaca aaataggtgt
     8041 gatcaatttc aaaaataaat atcaaatcaa agggatcaag ttaaaccagg aaacaattaa
     8101 aaagttaagg ataggaggat aaatttggct gagataagtt ggatcaaact taaaactact
     8161 atgtttgacg atgaaaaaat acgattaatc caagctgttc ctgagtcgga tgccatcatc
     8221 gttatatgga ttcgattact agttttagca ggaaagacta acgacgatgg tctgatatat
     8281 atccagagga acatgcctta taccgaagaa atgcttgcta cattgtttgg caaaaacgta
     8341 aatacggttc gcttagcgct aactacattg gcaaatttca acatgattga tctaagcagt
     8401 gatggactaa ttgccatcag taattgggaa aaacatcaaa atatcgaggg tatggataaa
     8461 gtaaggctaa aaaatgctga aagaaaccgt aaatacaggg aaagaaagag acaggaacgt
     8521 ctcaaattgg aaaatgacgt tagcgtgacg tcacgtgacg gtacagataa agatatagaa
     8581 gaagataaag atatagataa agaagaaaag aaaggtaagt attctgacga acacttacgc
     8641 cttgctaaaa agttgcaaag taatttaact gaagattttc caaaagaaat gaacaaagta
     8701 gatatcgaaa aatgggcaga cacaatcagg ttgatggaag aaagagataa agcatctata
     8761 gaagcgattg agtatgtgat caattggcta cctacaaatg aattttggtt tggaaatatt
     8821 agaagtgcta agaaattgag agaaaaattt gagaagctca aattcgaaat caaagcagac
     8881 aagaagaatc ataaaaagca aagtcaaaaa ctacagtaca gcaatcctag tgaatatgac
     8941 gacttgccaa tttaaaaagg agatgcatca catggaaagc ctagcaaatg ctatggagaa
     9001 actaataaga agagtattag tgcaaagcgg aaaatgtcca gaatgtagcg aacctttgta
     9061 tagttggcga gctaaaaata aggatggttc agaacgttgt aaaccaacat gcatgagttg
     9121 tggttataaa gcgttacgtg tgaaagagga tatacagacc gaacggatat ataacgatag
     9181 cttaaaagca cgagcgttga gtttttttca aaatggttcg gtattaacag ataaaacttt
     9241 gtttaaatgc aaaatggaaa attatcacgt agtggatcaa gaaacaaaaa tcgctttaga
     9301 aaaagcaaaa agctatacga atgaggttct gctgaaccat cctgcacatt tcattctatc
     9361 agggaaatca ggaagcggaa aaagccactt atcaatggcc acagcttggg aaatacttga
     9421 gcgctcaaat tatgacaaga aaatactttt tataagctat caagaattat tagagcaaat
     9481 aaagttttct tataacaata ctgaactgag aaaagaaatt gaaggatcgc ttatagccga
     9541 tattaaaaca actgatttgg tggtttttga cgatattgga gctgaattag gtagtggggt
     9601 atcaaatagt aggcagttta caaacaacac gttaaacacg ctcttagaag ccagacagaa
     9661 caaggcaacg attatcacaa caaacttatc tggtcccgaa ctaagagaag cctacggcga
     9721 aagaattgtt tctaggatat ttaagaattc agaaggttat gcgctgaaat tccaacaaac
     9781 agcagacaag cgcataaaac cagtgaaagg tagtatcgca tgaataaata ccgtaataag
     9841 aaaactgttc atcgaggtat caagttcgat tctatcgcgg aagcagagta ctacgatcta
     9901 gccttgtggc aagcggaagc gaatgactgg aaagtaaagc ttcaagaaag atttgagctg
     9961 atgccgaaat ttgaactcga aggcaaaaag tatcgcaaaa tcgagtatat tcccgacttc
    10021 acattttata aaaatggcaa acttgtaaaa gtcgtagatg tcaaaggaat gcagacaaaa
    10081 gactttaaga tcaaggcgaa attgttttgt catcaatatc aagttccatt gatattagct
    10141 aaaaaatatc ggaatacgtt caaggaagag cgtttttaaa gaggtggtcc atcatgacaa
    10201 cagaagaagt gattcaaatg cgtattcgaa gcattcaacg tgaaattgac gatctggaac
    10261 gaacaaaggc agtgatggtc aatgaaacgg ctagaaaggc aattgatttg cacatagaga
    10321 acttaagaag ggaaattcgt agattggagg aatgagcgtg gataagaaag cagcaatgaa
    10381 acgaatcatc gaactgacac attctgagaa ttggcaagaa gacaaagaaa tagttgcaga
    10441 agtccaaaag ctcggtaaat caatgtggac tgaaaaaacc agacggagaa tgccgagaaa
    10501 aattgcaatc tggcacggtg accgaattct agtaacaggt accgctgaac agttatctga
    10561 aattactggt ctgagcaaaa acatcatctg ggatagagct aggagcttat ggattgattc
    10621 aaaaggacga cagtttaggt atgtggagga gaaataatgg atctcattac acaatatagt
    10681 gatatcatcc tcaagaaaat catgatgaag attcagaaag acaaaaaatc aaaagaacga
    10741 gcggaattag ttaagttgga aatggctgaa acaggagcag gagtgcgaag tagcaggcat
    10801 tggaaagcag cagcaaacat tgaattttat tacaacgaaa ttcaaaaagg gttcgatcag
    10861 atgcgtgagc tggatcggca aacaaattgg agcaagaaac ttcatcaaga tcgtttcaaa
    10921 tttgtagaga agtataaaga gatattagac gaatacatgg agggcagcaa atgataccga
    10981 gatttcgatc gtggtacaca ccatttaaag gtaaaacaat tggacaagaa atgaaatatg
    11041 ggcaagcagg aaggttgatc actcatgctg aaatggctcc agataaatat gtgcttatgc
    11101 aatccacagg actgaaagat aagaatggcg tagaaatatt tgaaggggat gtagttctgg
    11161 ttaatgtaag taatggtttt gatcatttag ttaatgaaaa aacggttgta caagaatccg
    11221 agtttcattc cggattagtt tgtaaatcat taattagtgg aatggaatat agaatattca
    11281 gccaccaaaa gatgggatac gaatatgaag tcaccggaaa tatacacgag aatagcgagt
    11341 tattggaggt agagtgatta tcttagctac tgactacatc gattctttaa aagatgaaaa
    11401 tgggaatgtc ccagcattgc taaattgtgg aattaaaagt aagaatagaa tcattttgtt
    11461 acggatatcg gctgatttag caaaatatct ttatctgagc aagacagcag tatattacac
    11521 tgcggctaca cgttatcagt acaagggaaa aacaatcagt caggattatt atgatcgttt
    11581 aatcagtcct gacatacatg gaaaatcaaa atcagcgatc aagttatttg gcgcaataga
    11641 gatatatgcc gatgattttc caaatttatg gttgaaggag gaacagtaat gaaagactgg
    11701 ttagaagaag caagcgcctt agttggctgt ttcataaact gtgcgtttat atctgtaatt
    11761 attgcactgg tgggatttgt atcattgaaa gtgattatat tgctttggca gttaattttt
    11821 taggaggaac agcgatgaat aaacaggaag caatcaaaaa gttagaaagt attaaagtga
    11881 taggaaatga tgcactagct gcttgctata acgagagtat aaatgcaggt attacgttaa
    11941 tgaaaaaaat agacgaaccg aagaagctag ttattccaca actcgtggcc ggttggcttg
    12001 agaaatctac ggaccctttt acgaaagctg aaaaaatagc gtatttaatc aaatctaaag
    12061 atggtgattc atattatttc tgtgattggt ttgtacgaga tggcatagtg acgcaagaac
    12121 aaggagaaga attactcgct tgggcaacga gacaatcata tgaaacacta ttgagcttgt
    12181 acaacggcta cgaggtcgag aaagagccgt tgtacagtgt aataattgct ggcgagtacc
    12241 ttgtcaagga gatcagttgc agtaatgaag ttaaactagt atcaacagct tacctgccac
    12301 aataccttgc acaccactac caactgaccg aaaaacagat caaagcaatt gatgaaagat
    12361 actggccatt tgctgtgcca gtggaagagg tggcggaagg atgagtagac agataatgct
    12421 ccatatacca gacggaacaa aggcaatgac gattaccatt gttgctgcac aaaaagacgg
    12481 tgggttggcg ttgaaaacaa aaagcattga taccaaacag attttagaag gcagagatgt
    12541 cgagatagag atcgatgagg aggaagcgga atgaatgttc aagtttattt aaaaagagat
    12601 ttggccaggt ttcctcgaag ctgggataca aattcccacc catccgaggc agaagaagag
    12661 ggctatctaa tgtctgctaa catgatagaa attacaagag atgatgcgga tgagtttgat
    12721 aaaaaaagat catggtactc ggttccgaat ccaatgtata cggctgtaat agaagattat
    12781 catatatccg acagatttat tctgattgat ctagaaaggc ctaagaaacg aattaaacag
    12841 tatagacgtt gtggattttc aacaaagaaa tggtgataac aaaacagagg tgaagaaaaa
    12901 tgaacaacag acaccgcaga gtagcaaaac taagaaatca agaactgaat gtagcgaaag
    12961 taaagttcga acgggagtat ggtgtttctg cagaagaaac atataaagtg gcaagtcagt
    13021 gtgttgctga tgcaagtgat gctattcgta agtttggaat ttcgatacta gatattaaat
    13081 gggaggatac agaatgaaga tttatgtagt aaagtttgga aatcaatttt acagaagcga
    13141 tgaacgttct ataggggcta acacattatc cattgtagac atactccaaa gcgcaagatg
    13201 gtttgataat ctcgaagaag ctaaccaagt ttcacgacga cttggtggat taacgcaagt
    13261 atatgaactg gtcactgtcg atcatgaggg ggtagagtaa tgaaactaaa agacggattt
    13321 tacgctagta gtcatggtat cggcggtttg atgctagata tgccgacaaa gaaccctaaa
    13381 acacgtgaga aaccaaaatt caaagtcggt gacatggttc gctgtgaagc agaaggattt
    13441 atctatccat ttcgtggata tgtagaaaag gtattgtcga actcagcaat cattcgtatt
    13501 gaaaacacga tggaatgtga caagtggtta gcgaaaagca aagagaattt agctgtagcg
    13561 agattagttg acatggaagt aatcgagagc aaataaaaaa gccggatcgc tccgactaac
    13621 ataataaaac agacaagttt attatatcac ataaaggaga ggtttgactt gatgcaattg
    13681 ttacgagagg tagatttcaa acagacaaga tgtaatgcga gagatgtgct gaagaacttt
    13741 cggcgtttgg agcggatggc aggtcgctct ttgatagata ttaagtctcc aattattacg
    13801 gatatgccga aggcgccgaa gcacggcaat aaggcagagg acgcgatcat tcagatgatg
    13861 gatatagaag cagagagaga tgcgatttta gcggctttga tggctcttag tctgattagc
    13921 cgtcagatac tctactacag cttttgtgtg ccagatagct tctcaaacta cagaattagc
    13981 cgtgaagtgg gttattcaga aagaagtata caacggatga agtcggaagc tctaatagag
    14041 tttgcagaag catataaaca cggaagaata attgcttata aataatttgg cggttttttg
    14101 gcggaatgat ggcggttttt agctatttac cagtgatatt atggtagtgt cgaaagatta
    14161 gtgataggtc tgagacaaaa taataataaa aggaacatcg ttttattatt gtttcacaat
    14221 taagcttcga tagacagcaa cggaaatatt aagaataagg atgtgaattt caactccttc
    14281 taaattgttc ttattatcta tcatccgttg ctgtctattg tttttttaat tattcacacg
    14341 ataactaaag gtgagtgaag agaaatgatt ccattaataa tttcaatttt tgcgctctgt
    14401 cttaatgtct atatgattgg atttaaaaat gggcaaaata aaaaatagta gcagccaaga
    14461 ataattttat agtgtcactg tggcggaaag ggtagacgct taaaaataag gtcaatacgt
    14521 cgagggatag ccttaacgtt ttatgatttg accatgcaat gttcgattca ttgccagtga
    14581 ctttggcaac cgagggttgg aaatgggcgc tcaaagtaca cgagcaaggc gaggtcgata
    14641 gtaatcgatg gaatcggtgt aggttgcttg atagagctat aactgcatct cgtttatgag
    14701 gtgtagtttt tacagattag atcactcttt gagtggtctt tttattttac acaaaggagg
    14761 taacaagaat gtatagacca caatacttag aacagaagta tgaagtaatc actgtgcaaa
    14821 acggtaacgg tgagatagta cgaaagtata gaagaccaat aaagagcgat acatacaaac
    14881 gaaaggaaag caatgaagtt attccattgt atggcaaaag aatagctaag cattaaataa
    14941 gattgcgaaa ggagacggaa tatgaccgag gaattctata gatggctatt acagttgata
    15001 agagaagatc gtttagttaa gttctatcag tctcctaaat ggcgcaggct tagagagaaa
    15061 gcgatgaaac gagatcacta tgaatgccaa gagtgtagaa gactaggtaa gtatcataga
    15121 gtagaaaacg ttcatcatat aaaggaagtc aaggatagac ctgacttagc tttagattta
    15181 gataatctta tttgtttatg tgttgaacat cataatgaag ttcatggcag atatcttaca
    15241 gcattagata aacaagagaa gaagatagaa agctttgcta acttcgatgc aagtgaaagg
    15301 tggtaagtgc atgatcatca atgataatgg cagagagtat gatacagaaa agattgaaga
    15361 gtattcatct tatactcagg gattaattaa acgtttgata tacgttcgct atgtagatat
    15421 tagggatctg ttatcagata actgttgtag taaatacaaa gtgaatcaag taagagaagc
    15481 gttgaataaa gataataacg ttgaaagaat aaaaaatatt tttggatata gcattgaaga
    15541 gattaattat tacattgact tcgctgaagc tttcattccg atggtgagat aaccccccct
    15601 taaaataaat cgcaaatttt ttgggggtga tgaaacggag ggggctgtca ggaaaagaga
    15661 ttttttcgaa ctttatcatg aaaggagggc taaaatgttt aaaaacgaat tgtctcaaaa
    15721 tcgctacaga gaaaaattac gccgctcttt aataagccaa ttggaaagtc agaaaacaaa
    15781 tattgagcca ttcttagata atgttgatcg ttatatcagt ttatgggaaa cggcgatatc
    15841 actggaagaa gatatatccg agaacggcat tagactggag aatggtaaaa agaatgaatc
    15901 agtagcgttg cttgtttctg tcaacaaaca aatgggattg atgttggata aacttgccat
    15961 tactcctgaa ttggtaggtg aagcaaatga atcaattcct gagttataag catattgaaa
    16021 attggttcaa agctatagaa gaaggcacta tcaaggtatg caaagagcaa ttattgctaa
    16081 aaaattatct agaagaaaga gtctttacta gagaagatat ttacttcgat aagcagatgg
    16141 tagaggattc aatcaatata ccagcacaat actttccatt cgaattaatt ccgtgggaaa
    16201 aatttctaca atgttttatt tatggtgttc gatggaaaaa agataaaaca ctagtgttca
    16261 atagatatct ttcattaatg ggacgtggta atggtaaaac tggttttgct tcttggaaca
    16321 acttctttct actaaccgct aaacacggta ttaaaaatta taatattgat atctatgcca
    16381 ataatgaaag ccaagcaaag actagttttg atgatgtatt taaagtaatt aaagatcatc
    16441 ctgatttaga taaaaaagta tttaaagcta cgaaggaagt tattcaaaat atcgctacaa
    16501 acagcaaact tcgttataac acggcaaatg ctagaacaaa agatgggaag cgaccaggtg
    16561 caaaccgctt tgatgaaatt cacgaaaatg aagattattc aatgataaat gtggctactt
    16621 ctggtggtgg taaaattcga gattatagag aattttatga tacaactaat ggtcatgttc
    16681 gtggtggtcc gcttgatgac attatagaag aatcaaaaat gattctttct ggagaacttg
    16741 gaattgacaa ggatggagca gaattttcta gtttgtttcc atttatttgt cgcttggata
    16801 acgataatga agttgatgat cccgacatgt gggaaaaagc ttgtccaact attaattaca
    16861 atgcagattt aaaacggaaa atgtttcaag aatactctca aatgcaacgt aatgctggtt
    16921 taagacttac gttcatgacc aaacgaatga acagacctat ggaagataca cgatttgctg
    16981 ttgcttcata tgatgatgtt ctgcatacga aagaaaaaga atttcctgaa aaaatggatg
    17041 aagtgatagg aacagtcgat tttgctgata gacgagattt tgccagcgtt gggttgctag
    17101 gaaaatacga taaagatgtt tattttacac aacatacttt tatccacgaa tcagcccttc
    17161 gattacaaaa catcaaacga gaggttatag atatttctat agatcaagga aaatcacaga
    17221 tcgttcatgg aaaaaatata gaagctgatt atattgtagg ttggtttctt gaaatgagta
    17281 ataaatatta tattaaaaaa atcgctatgg atatgtaccg tgcaaaaata ttgaagcccg
    17341 ctttagaaga agcaggtttt actgtggaaa ttgttcgaag cggatctgtt acacatggta
    17401 tgttaaaaga tctggttgat gaccttttta ttaatcaacg tttatttttt ggtgacgatg
    17461 cgattatgcg ttggtattgc atgaatgtat atgaagagca tatttctaat ggaaatatac
    17521 gctatgaaaa aatagaacct gaaactagaa aaacggatgg ctttttttca ttccttcatg
    17581 gtttgaattt tttagatgat atttatgatt ctgctcctgt aacagtcaca aatagctcag
    17641 tagaaaatac aggaactgga tttactcctc tagtattcta acttgaaagg aggtgagaaa
    17701 gtggggattt ttcaaaaggc ggtaggatac ttcacaaaaa aagcaacggt tcctttagaa
    17761 gaatactttt gtaaattgca agttgatttt gtgtatcgaa aatttgcgat tgaaacttgt
    17821 attgatttga ttgcaaatgc gatgagtaaa gcggaattca agtcatatga agatggaaaa
    17881 aataaaaaga atgatcttta ctataggctg aatgtagctc ctaataagaa aaataatgca
    17941 acagaattta gaaaaaaact gatcaggaga ttaatattct acaatgaagt attgatcgtt
    18001 tctccgtcta ataattctag cgaaatattt attgcggata gttgggatgt cacagaatat
    18061 gcattgaaag atgatgtgtt ttctcaagtg caaattaaca acatagtcct tgatagagaa
    18121 tttctagaaa gtgatgttat ctatataaaa tacgcagatc aacaaattag gcaactagtc
    18181 gatgcgtatt atcaagcgta tgggaaactc atttctagtg ccatgaatgt ttacaagcgc
    18241 tctaacgctc gtagatacgt actgaaaggg aatttattcc gaccgcaaga caatacaaca
    18301 caagatcaaa tcaataaaat gatgacatca caatttaagg cttttatgga agctgataat
    18361 gcaggtgcgg tatttcaatt acaaaatgag tacacattag aagatttcag cggaaacttc
    18421 caaagcaatt caagagatat aaaaaactta atagacgaca tctttgagat gacagcagca
    18481 gcgtttcacg ttccgaaaaa cctactaaag ggagacatga gtgggttatc ggatcaagtg
    18541 gacgcttttt taatgttcga aatcataccg attgctgaac ttattcagga tgcgtttaac
    18601 gctagtctct atgaagtaga agaatacttg tcagggaatt ttgtacgtgt ggatacaact
    18661 atgatcaaga ttactagctt caaagatttg gttgacgcta ttgatgtagg cattagaaat
    18721 ggagtattta caatcaacga aggaagagaa cgcgttggaa atgatcgctc tgataaggcg
    18781 atggcagatg aaatatttat aactaaaaac aatcaacaag tatcgaaagg aggtgaggcg
    18841 aatgacgaca atgaaaacat ttctagcagt aaagaatgaa ggcgcagtac cgcaaatttt
    18901 tattcaggga tttattggtt ctagttggtt ctttgaaggg aatactgaca agggaatcaa
    18961 aaatattttg gatagtctag gtgatcaaga agaaattgaa gtagtaatta attcaaacgg
    19021 tggagacgta tttcaaggga ttgctattgg gaacttactt aagtcaaata aagcaaaagt
    19081 taacgttgtg attaacggct tagccgctag tgctgcttca attatcgcaa tggctggcga
    19141 tactataaaa atctacaaca atgcacaatt gatgattcac cgcgcttcca catacggaga
    19201 aggaaatgtc gatgacttcc gtacgattgc tgaccaactg gaatcaattg ataaatcggt
    19261 aaaggcttca tataaaacac gattcaatgg cacagatgaa gcattgcaag aacttcttga
    19321 aaaagaatcg tttatggatg cagaaacagc tttgagttat ggattggtcg atgaaattat
    19381 cgatgcagaa aatagctcag gtactgaagc taaaaaagaa caaagcgttg aagaaatttt
    19441 gaatgacgtt aaagaaaaaa gagcagaaaa aattgctgca tttacagcag cattaaataa
    19501 aacatttgga caaggagatg taaaataatg acagttaaaa atttaaaagg tgtaacagct
    19561 gcaagcgacc aattgatgaa agcttttaaa gatggtaacg aagaatcttt tagcgcagct
    19621 atggtaagct tatctaagga aattcaggat aaaattttag aagaagcaac agcaaaaaat
    19681 caagatcaat tagtattaat gaaccgtggt cagcgtgtat taactacaca agaaacaaaa
    19741 ttctataacg aagtagtgaa aaacgaaggt tttgcagggg tcgaagaatt agtgccagct
    19801 actgtatttg aacgtgtatt tgaagattta gaacaatctc atccactatt gcaaaaaatt
    19861 acttttgtta acacaactgg tgtaacagaa tggattgtgt cacgtggagt caatccagca
    19921 tggtggggta aactttgcga agctgttaaa aaagttttag ataatggctt tgatgtaatt
    19981 aacatgaagc agttcaagct atcaggttat attcctgtat gtaaggcaat gcttgattta
    20041 ggtccagtat ggttagatcg ttatgtccgt actgttttag tagaatcatt gagaattgca
    20101 ttagaacaag caattgttga tggtactggt aaagatatgc cagtcggaat gatgcgtgac
    20161 atgagcaaac aaactagcgg agaatatgct gaaaaagaag cagaacctat tacagcttta
    20221 gatgctgtaa ctatgggcgg tttgatggcg cgactatcaa aattcaatat cgaaggtgtg
    20281 aatgatccga tttatcgtaa tgtgaatcct tctgatgtgg tcctaattgt gaatccaact
    20341 gattactggt ctaaagtatt cccagctaag actgtactaa ctgctaatgg agaatacgta
    20401 caagtattgc cagtaccagt ttcagatttg cagtcaacgg ctgtgccaga aggaaaagca
    20461 gttattgggg tagcctcaga ttacttcatg ggtgtaggat ctacactaaa aattgaagct
    20521 tcagatgaat accgttttgt tgaagacgaa cgcatttatc tagctaaaca atatgcaaac
    20581 ggtcaaccta aacgtaacga tagtttcatt gtattagata ttagcgcttt gggaactact
    20641 actacaacta caaaaccaac aaccacaaca actacaacac aagcgtaggt gatcagaatg
    20701 aagtatattc tttgtcagcc ggcaatcaat cggtttaaat gggagcttga agtttgttta
    20761 actaatctga agaaactagg aatcaaagat atcgtattgc ttttcagcag acacgatgat
    20821 cagattccta ttttttttga gaaggaatat ggtgttgaag ttcatgtgta cgatgatctg
    20881 cgggacgaca aagagtatat tccttcgatt aaaccatatt tatggtggaa atatttagaa
    20941 gaagatcatt cgcgtgagga cgaccgatat ttctatatcg attcggatgt cattttcaat
    21001 aaaagaatta atttgcgcaa attgccttct aaagatgatg tttggtattg tagcgactgc
    21061 tgtagttatc taagtcttga ttatattaga agctgtgaaa acggagaaaa tattctaaaa
    21121 gatatggcaa acattgtaaa tgttacagta gaatctttgg aaactataaa cactaattca
    21181 ggaggcgcac agtgggttat taaccgtcct aaagcgaatt attggaaaaa ggtttatctg
    21241 gattctaatc ggctatatcg ctaccttaga gggcaaaaaa caaatataca aatctggaca
    21301 gccgagatgt gggcacagct ttggaacatg atgtatttca atattggtcc taaagttcac
    21361 gaggaattag acttttgttt tgctactgat ccaatagaaa aagttaaaga agtaaaaatc
    21421 ttacacaata ctggagtaac aacaaacgat gaagatttat ttttcaaagg gagatacgtg
    21481 acttctacgc cttttgatga agatttatca tttgtaaaca agaaaaaatg ctcttacgca
    21541 tatgttaaag caattaaggc ggtggttaga tgacgcctga acaagtgact gaagaattgc
    21601 taatagctgt gaaggataat atttacgtta cctggaacga agaagatgag tcaattaaaa
    21661 agatgatagc taaaaatgct gtttatcttc aaagtaaagt gagtacaaca ctttcttttt
    21721 ctcctgaaag cttagaatac ggattgctaa tcgaaagatg tagatacgac tggaatcgtg
    21781 ctttagatga gtttgaacaa aatttcgcta gtgagttatt aggtttcatt caacattatg
    21841 cgctacaaga atatattgca ggtgatgtga atggcgaata atcgtagact cgaagaaaca
    21901 ttcaacgatg gttggttaaa gattttgacg caaactacca aaagaaatga actaggaaaa
    21961 aagattggtg tagaagatac agaaatcact tctttaaaat ttagaaatct ttccatgaga
    22021 gatagtgata taacagctat ggatgcgatg ggatcgaaat taactaagaa agtaaagact
    22081 ccatttcatc caatcgccaa gaaatttaat aaagatcaat attttatcgt aatcgatagt
    22141 atgcgttaca acgttatcta tgccgattac gataattttt atatctattt ttatcttgaa
    22201 agtgtgggtg aatatggtga ttgataattc taaagaaaaa gaacgtttaa ataagcaaat
    22261 ttctgctatc aaaacttcct tagaagagca ttttggcctc aaactctttc aagactccgt
    22321 aggcgaggat gagctacctg atgattttaa ttacttcatt ctcgaaacag gagaaataga
    22381 aatgatcact gagccaaaat atagcgtggg tcaaaatcta tatctaactt tctattcaga
    22441 aaatagagaa gatttaacag gagattcact agatattatt tcattgattc aaaatcgttc
    22501 gattcgtttt cagagaatgg atcccaatca tttaaaacta gagaaccaag atcgctatat
    22561 cgatcaattg gtatttacgt ttagacgatt attgaagagt gattgtcatg gctaaaaata
    22621 gttgggagct aaaaataaat ggacatgatg aacttcttgt gcggatggaa cgctattcaa
    22681 gcgagagcga acgactgatt aacgaagcat tgaaatcaaa aggttcggct attgcagtgg
    22741 ataggattac agaaaaaatt cctgtttctg aagcagattt aagaagaggg caccaacacg
    22801 caaaaaatag tcgtccactt aagactcaat acattaattt gggtttcatc attagaccta
    22861 caagaaaatt tgagtattta aaatatcctg atttggggat aggtacttct aaaagaaatc
    22921 agccggacga atttatgaga agaggattag gtcttgcact tgatccaatt acagaacttc
    22981 tgattcgtca attcgataaa ttaaataaat aggaggaaca acaatggcta aaacaacaac
    23041 agtaacaact tttgacaata taagtattaa aagaatttct tttaatttta agaatgcaac
    23101 aaatgcaatt tcaactgatt gtaatggaca attagatggc gaaacagaaa tgcagagaat
    23161 tgtaaaaaaa tgcggttcaa cagaagtaaa atcgaaatct aaaccaatca atatgacggt
    23221 aacaattact gcacatgtac cgatggaagt ttatcgacgc ttcaatgggt tgaaacaaga
    23281 tgaacgtatt aaatcgggaa tttactctta tggtcctgat tccgtagggg aagatttctc
    23341 acttgctgca gagatcgtgg atgacttcga agaaaataga aagttagttg gtatgttagc
    23401 atgcacttcg aatacaggat taacattctc tattgaaaat ggtgcggatg aagtagctgc
    23461 gttagaacta gaaacaaaag ttatgcaaga tgaatttggt aaattttatc atgaagcaat
    23521 tgttgcagaa cttgaagaag acttaacaga tcaatggatg acgaatctat ctgctgatgt
    23581 gattaaaaaa acttcagttg tgacaactac ggccactcaa tcacagtaaa aaaaacggag
    23641 gtagcgaaat gaacgaagat tactcaaaaa ttgaactaaa cgatggaaca attttgaatt
    23701 tagaacctaa actgaatatc aagaaattat tgatgatcaa tagagatttt aacacagacg
    23761 agtttgcaaa aatgactgtg ggaaaaggat ccatggatat ttctgttatt caaggtgcaa
    23821 aggctgtgta tattgcttac cgccaagcga acatgactga ttatatttca ttcgatgaat
    23881 ttatcgataa atgggatttt gatatggcta ctgccagcta tatttatcaa ttgatgatgt
    23941 tcaaacaagc acgcgatgct tatcaaaaag aatttgaaaa agcaaataag gaaaaaaagc
    24001 ttcaaaagta aaaattccaa agctcttagt tgaaacgtgg gtcgatgtct attcgatgtt
    24061 gaccgacgtt ttttctatgc cttcagattt ggttttaagc gatatctgtt tagatgacat
    24121 tttgcaaatg gcttacaaca agagtgctta tgaaggatgg aaaaactatg caataaacca
    24181 atcccagaaa aactaaagaa aggaggtaaa aaatggctaa aaagagaaca gaagcagaag
    24241 taactttcat agctaacgat gacggattga aatctacgtt aaaagaaatc agtgctgaat
    24301 taactaaaaa tagagcagaa ttaaaactag aacaagctca attacaacag actggttctg
    24361 aatcagacaa gttaggaagt aaattatctt ctttagaaaa gcagtatgaa ttacaaagtc
    24421 aaaaagttga agtaactagc caacgtttag ccaatgcgaa aaaatattat ggagaaaatt
    24481 ccaccgaagt tcagaaactt gaaagagaac tgattaatca acaaacagcg caacaacgtt
    24541 tgtcaaacga aattgataaa acgagtaatg cactagctca agcaaaaggc gaaatacaga
    24601 cgtacgagtc tacaatgcaa cagttggata gcgaacaaaa aaatgttcaa gctagtgctt
    24661 ctctgattga atccgaatac aaaaaatggc aagcaactgc tggtcaatca gcttctgaag
    24721 ccgagaaatt agcgaaagcc caagaatatg tttctcaaca atctgaaaat gcggagaaaa
    24781 cgatagatat cctaagacga cagttagaag ctacacagtc tgaatttggc gctacatcca
    24841 cagaagcaat gcagatggaa gcgaagctta atgatgctga acgtgaattt gaagagttag
    24901 gacaagctgc taaaaatgta gatacaacta acttggacga tatcggaagc aaaatagata
    24961 tgaataattt aatggaagct tctgacgttt taagcgacat tggcgataag cttacagaat
    25021 tagggaaaca agcagtggac tctgctaaca gtgtaggtag ttcccagagt aagatacaag
    25081 ctaattttgg tttgtctaaa caagaggctg aagaattaac gaatgtagcc agagacattt
    25141 attataaagg ttttggagaa tcgttagatc agtccacaga tgcattgatt ttggtaaagc
    25201 gtaatttagg agatttaaat aatcaagatt tacaaaatat cacggaacaa gctatggtcc
    25261 tagaaaacac catgggcgct gatatggatg aaacgttacg tggtgtaaat ggcttaatgg
    25321 tcaatttcgg cttgagtgct caagatgcaa tggatttaat ggtttcgggt actcaaaacg
    25381 gtttagataa aacgcacgaa ttaggcgaca atatggcaga atatagccaa ttatggagtc
    25441 aaatgggata ttcagctgat gaaacgttcg gaatgcttca aaatggttta gatgcgggtg
    25501 cttataacct tgataaagtc aatgacttag ttaaggaaat gggaatatcg ttaacagatg
    25561 gtcgatttga gcaaaacatg gatatgttta gtgaaagtac tagaaaagct tttgaagagt
    25621 ggaaaaatgg cggaggaaca caaaaagacg ttattaattc catgattcaa gattttagca
    25681 atatggatgg tcaatacgac caattaaata aagcttcgac aatttggtct gcgcttggcg
    25741 aagataatgc gatgaaagtt gtccaatctt taactgatgt taaccataca tttgatgatg
    25801 ttagtggatc tgcacaaaaa atgaatgaag attctactac tccgttacaa gaattaaacg
    25861 gaaaaatagc tgaattaaag gattcattag ctcctatagg caacacaatc atagatgcac
    25921 tcgaaccagt aattgatttt ctaggaaaga tggctgatgc gtttaataat cttccacaac
    25981 cagtacagga ttatgccgta gcgattggcg gattgactgc tgcatttact ttattaatgc
    26041 caataatagt tggcttcatg gctctaggtg gtcctactac attaataata ggagcagtta
    26101 ttactgctat tgctggagtt atagcaatta taaaaaactg gggcgcaatc actgactggt
    26161 ttagtgattt atggaaaaaa tttaccgatt ggttaggtga tacctgggaa agtataaaag
    26221 aaagtgcctc atcagtttgg gatggagtca aagaaacctg gtctggattt gtagattggg
    26281 ttcaagaaat ttggcaagga gtttctgatt ggtttggaga gttatggagc ggattagttg
    26341 aaggagcttc caacatctgg caaggagtcc aagagacttg gcaagcattc gttgattggg
    26401 tttcaaatat ttggaacgga gtcaaagaag tatggtcgat tatttgggca gacattgtag
    26461 gaattgttca aataccatgg acattaataa cgtcattgat tcaagctggt attaatatta
    26521 tcgtgggtat ctttgatgta gctggacagt tattaggcgc agcttggcaa gctgtttgga
    26581 cacctatttc tgatttcctt aaaaatactt gggatactat gacacaatgg ataagcatcg
    26641 cttggaatgg aattgtaact acattccata ctatatttga tccagtagtg gcatggtgga
    26701 atggtatatg gacatctatt agtactacgg cttcaaatat ttggaattca attagtgcaa
    26761 cagcttctag tatttggaac agtatcaaga atacaatcac tagcttggta caagcagctg
    26821 ctacagtaat tcaaaatatt tggtcaactg tatctagttg gttaggtgga atttggaatt
    26881 caatcagctc tacagcatca aatatctgga atagtgtgac tagtagtata agcaatgcta
    26941 taaacgcagc taaaagtgcc attcaaagtg tttggaatag tatatcttcg tggatcagcg
    27001 gaatttggaa cggtatcaaa aatactgctt tgaatctttg gaatggaatt acaagcacta
    27061 ttagctctaa agtaaacgat ggaaaaaatg caatttcaag cggttggtcc aatctaacag
    27121 gtattgtttc cgacatattc aataatgtta aaagtacaat tgctaacata tgggaaggca
    27181 tcaaaaagac tgttagcgct ccaattgatt ggattagaga caaaatcagt ggcatttttg
    27241 ataatttgaa tatttctata ccacatattc cgttaccgga atttatcatg gaaggcagct
    27301 ttaacccgct aaaaggtcaa atcccccatt tgcgtgtaaa atggcatgct aaaggaggta
    27361 tctttactaa accaacttta ctaggtggaa tgaacggtgt cggtgaagca ggacctgaag
    27421 cagttttacc tttgaaaaga tctgttttgc aagaaattgg tgatcgtatc ttgagtagca
    27481 catcagtttc atctagggca caaacgattc aacctgtgaa taactacgaa ttcaatttca
    27541 caattgatgg taacgcagat gaggttacta tgaagcaaac aactcaacaa atcattgata
    27601 gcattacaaa aattcaaaat gataatgctt cggcatggcg ttaaacagga gagtatttct
    27661 cctgtttttt tagtattaaa aaggatgtga aaaaatgact gattgtatac attctataat
    27721 cgatggattt cctgattatt tgcataaatt ggctttagct gaaagaccaa ccataccttc
    27781 tccaaaaaga cagagagttg aaacttctgt tttaggtagg ttaggtggct tagtacaaga
    27841 ttactcgttt gaagatatgt cgtttacatt gcactataac tatttagagg atgtggaaga
    27901 ccatcaagcg ttcaagcaat cgttttatat catgcgtcat tggttaaact atgcaaagaa
    27961 attagaattc tctgacgatc ccaacgtcta ttacgttatc cagactatcg atattgggga
    28021 tgcagaaaac gatattgttg aatggggaga gttcgatgta aatattactg cgaaaccatt
    28081 cgcaagagtt caagaagatg tacctataac cgtagataaa ccacagtcat ttaacttgct
    28141 gaataatagt ttagaagaaa gttttccaaa gattatcatc actccttcag ctacttcatg
    28201 ccagttcatc ttaaatgatt atgtgtttag tttcgaaggc ttagtagcag gaactgatgt
    28261 agtcattgat agtgatttga tgctttgcta cgaagagcaa tcggacggag atattttaga
    28321 tcggtccaac aaaatgaaga ccatgcaata tccaacgttg caagtggata ttaatcattt
    28381 taattgtact ggtttgagca aaatacaaat ttatcgtaac gggttaaggt aggtgaaata
    28441 gatgatcgat aatttaataa ctatttacga taaaaatgac gcgaataatt tagctgaaca
    28501 tttatatgat acgcaaggtt taggcgcttt gtcagactgg ttaacagcta ctgttagcaa
    28561 taaactaaac ggagccgaga tatttcaggg tacttattca ataaacggaa ctaatgcaga
    28621 tttgattgta gaaggacgta ttattcagtg ttatgtagat gaaaatcgag caaaacagcg
    28681 tctacggatt tattatgcaa aaacttctgt aataggcaat acgatagaag taaaagctga
    28741 acctattttc aatgatataa gaaaatcggt gttgaataaa tatgacagcg gaacagaaaa
    28801 gatcactgct actcaggcat ggcaaaacgc aaaagtttta gcgaaaccag ctatcccttc
    28861 gcagttttct ttctcgtcat tagtagatac gcttgctaat gtgaagatag aaaaggcgaa
    28921 ttttttagaa ttctttggtg gaaaagaggg atctattcta gatcgatttc atggtgagtt
    28981 tctaaaagat aataacacat tacgtcatga aaaaagtcta ggtacggatc ataaaatcaa
    29041 agcgatttat actaaaaact taactggtct tgacttagag attgatgctc aaagtgtttt
    29101 agttggagtt tatccattca ttagcagctc ttcagaagga gaagacgaga tcactctacc
    29161 agaagaagtt attttcacgg attacgtgga tgattatcct gctggatatg tttcttttgt
    29221 tgattttaaa gacaaagcga ctgatgtagc cacattaagg gaagctgcta aagactggtt
    29281 gaaaacaaac atagataaac aaaaaccaca agtgagtggt tcgattgaat tagtaccatt
    29341 gaggcatcaa agaggctatg aaaaatttgt tgatctagaa aaagtttcga tgggtgacgg
    29401 agtagatgtg tatcatccac agttaaaagt gaatatgtca gcgagaattg tggaatatac
    29461 gtttaatgtt ctaaccaatt catacgataa attagttgta ggaaacgtca aaacaaactt
    29521 cttagaaaac acagagaata atgtcagcaa tttgattaat gatgccattg atcaattgaa
    29581 aaatggtggc gaaatcagtg atttaatcaa tgatattgta gatcatcaaa ctgatatgat
    29641 tactggtcaa aatggtggtt acgttttatt agatcctaaa gaagccccta gtcgtatttt
    29701 gattatggac acaccagata agaatactgc acggaacgtt ttgcaaatca acaacgctgg
    29761 tattggtttc tctaaaactg gcattaatgg aacgtatgac accgcatgga cgttagatgg
    29821 cggattcaat gcctcgttta ttacagctgg tgagatagta gggattacta ttagaggtac
    29881 tacattaatt agtgatggca ctgattatag aacaagtata gctaatggca aaatgacttg
    29941 gtactcaaaa aaagttaaca aagatattat ggagctagaa gcacgtgatt atgtaagtgc
    30001 tgatgccggc attgtatcat acaccatgaa aactggtggt ggtttcatga ttagaaatcc
    30061 acagggtaac ttggttttta gtacgtggga taatggtaat aacagaccgt ttttatcttt
    30121 tggtgcgcca aatttcagat acagtaatgc tagttatata aatgatggtg acggtaattc
    30181 tttaggtatt gatggtagtg caggtaattc atgggaattt aaagtagctg gtaggactat
    30241 gaaatttact agtgacggta tgctaacgtt gccaggttgt ttttttggtt catgggaaga
    30301 tgggaaactt gctagatttg aacaatcaac ggtacaagta tataaagatt ttactgttag
    30361 aggtactaaa aactcaaccg taccaacaga acattatgga caacgactat tgaacgctta
    30421 tgaaactcca gaatattatt tcgctgatta tggggaagcc gttacaggtg atgatggtaa
    30481 agttcgtgtt gatattgacc ccatgtttgc tgagacagta aatctaagtc ggtatatgac
    30541 acatgtgaca cctacagaac tagttttgtg tgctgttact catgaagatg ttgaccattt
    30601 catcattgaa actagtaagc caaacgtatt ggttagatgg aatttagtgg cacatcgact
    30661 agggtatgaa gatgttagat taaaagagga tacagcatat gatagcacag tgcttgacca
    30721 aaaacgtttt taaaacgaag acaaggaggt atataaatgg ctagcagttt atataatttg
    30781 gctttagatt tcagcaaaga attaaactac accaaagcta ttatggctcg tcaaggtgat
    30841 aaagggatca cggtgactgt taaaccgttt ttaaatggct tgcagatgga tacgagcggc
    30901 ggaacattta ctttaaaagg aactacgcca tctaaccgtt acgtagatag tgtcgctact
    30961 agtgtaacta gtgaagaagt cacattttct cttgatggca catttatgag tgaagcaggg
    31021 tattataaac actgctatgt agaatataga aaagacgatc aaattttaac gacgcaagat
    31081 atcatttttt tctcactagg agtgtctgac atttcgcaag gccaagccga tgaatatgtt
    31141 tcgcaattag aagaattgat tcgaaagtat aacgaaactt ttgatgcttt tctggctgaa
    31201 attaaaggta gaatggatag cttaaataaa cagattactg atttaactgg tcaagctaaa
    31261 acactacaag acaagttaga tgctctgaaa gaagaaattt ctaaattagg taacttacat
    31321 gtgatgtact ccaacagcat cgacttcggg ggctatgatt atagtgggaa tccgaattta
    31381 atgtccaaac taaaatcgag cgattttaac gttggttacc acgggtcact aactaatgtt
    31441 aacggaatgt tacattttat gtctgatggt acaggggaca ttgatatgtt tacgcgtatt
    31501 aatacacctc agcttgctag tggcaaaaca tatactctga gtgcaaaagt tcgatttgat
    31561 gaaggaacta caggagctat taataaatta cgtttggtat atcgtacatc accaggagaa
    31621 aatatattat tggaagcaaa taatacaact attacaatag atgatgtagg gaaagaaata
    31681 acaatcaaag gcacagctaa cgttaattat caaatcacaa atttagatcg tttttatatt
    31741 agtgttagtt tttctaacag ggataaaata aatggtggat ttaaattgta cgacatcaaa
    31801 atcgaagaag gctcaacagc cactccgtat cagccaaact tactagatga cccttactgg
    31861 gtaggtaaaa catcgttggg taagaatatt gcaaataaag gtacgacgtt cccaattaaa
    31921 tctagcgcgt acgaaatata taaaggtaac acggaagaag agcttataat aggtcaaacg
    31981 tatactatca cgcttaaagg aacaaaaccc gcaagtcaaa cctttgtagc atataattat
    32041 tggaacgtta attttggaga tctaaaacca gttgagggat tgacagacgt atggtctcta
    32101 acattcacac caacgaaact tgaaccgggt ttgcctaaag accttcgcat ttttcagtcg
    32161 cctaaagaaa cggccggcgc atgccgaatt gactggctca agatcgaaaa aggcgacaca
    32221 cgaaccccga atattgagca atataaatac cgaggaatcg gcatgcgaga ctcaaacaat
    32281 ccaaaagatt atgtatggga tctagaacct agctatgttg agaataacct agctacagat
    32341 atcaaggttg ctgaaatcac aggtaaagca aacaattata ccgatgggaa agtatcggag
    32401 attaattcgc agttgactgc ttcaattaat gaagtagaca ccacagctaa ggatgctcaa
    32461 acaaaagcga atgctaatgc gactgctata gatgaattag acaataagat cgatgaacgc
    32521 attaatgata cagctactac cacattaaca gttacaaacg ggaataccgg atcagcaaag
    32581 ctttatcgtg aaggaaaaac agtttctata tattttgtgg ctttaaacgg aaaaagcagt
    32641 ggtggaaatg attcaacgat actaacaatt ccagaaggct atcgg
//
LOCUS       DAIGWC010000028        32320 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.028, whole genome shotgun sequence.
ACCESSION   DAIGWC010000028 DAIGWC010000000
VERSION     DAIGWC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.028"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..433)
                     /locus_tag="NOB74_001303"
     CDS             complement(<1..433)
                     /locus_tag="NOB74_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220502.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNM"
     gene            complement(992..1309)
                     /locus_tag="NOB74_001304"
     CDS             complement(992..1309)
                     /locus_tag="NOB74_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI1220503.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            complement(1310..1564)
                     /locus_tag="NOB74_001305"
     CDS             complement(1310..1564)
                     /locus_tag="NOB74_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI1220504.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            complement(1824..2042)
                     /locus_tag="NOB74_001306"
                     /pseudo
     CDS             complement(1824..2042)
                     /locus_tag="NOB74_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2602..2688)
                     /locus_tag="NOB74_001307"
                     /pseudo
     CDS             complement(2602..2688)
                     /locus_tag="NOB74_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            3854..4894
                     /locus_tag="NOB74_001308"
     CDS             3854..4894
                     /locus_tag="NOB74_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI1220505.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
     gene            5741..6073
                     /locus_tag="NOB74_001309"
     CDS             5741..6073
                     /locus_tag="NOB74_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HCI1220506.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            6692..7033
                     /locus_tag="NOB74_001310"
     CDS             6692..7033
                     /locus_tag="NOB74_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HCI1220507.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYYQKLTDNPIGFGLLPEDDEGNEWFKMTLTNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            7147..7386
                     /locus_tag="NOB74_001311"
     CDS             7147..7386
                     /locus_tag="NOB74_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220508.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            7498..7692
                     /locus_tag="NOB74_001312"
     CDS             7498..7692
                     /locus_tag="NOB74_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220509.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYINDMQITGKEKACLLGSMKNFE
                     QLRRTYVKTSSNCQLLLEVS"
     gene            7778..8449
                     /locus_tag="NOB74_001313"
     CDS             7778..8449
                     /locus_tag="NOB74_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCI1220510.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQQEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            8502..10478
                     /locus_tag="NOB74_001314"
     CDS             8502..10478
                     /locus_tag="NOB74_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI1220511.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            10493..11245
                     /locus_tag="NOB74_001315"
     CDS             10493..11245
                     /locus_tag="NOB74_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1220512.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLESNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            11261..12016
                     /locus_tag="NOB74_001316"
     CDS             11261..12016
                     /locus_tag="NOB74_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220513.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKNRVKKLSSDQLKLVSNEETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            12029..12289
                     /locus_tag="NOB74_001317"
     CDS             12029..12289
                     /locus_tag="NOB74_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220514.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            12286..14376
                     /locus_tag="NOB74_001318"
     CDS             12286..14376
                     /locus_tag="NOB74_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI1220515.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            14403..14867
                     /locus_tag="NOB74_001319"
     CDS             14403..14867
                     /locus_tag="NOB74_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220516.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            14864..15106
                     /locus_tag="NOB74_001320"
     CDS             14864..15106
                     /locus_tag="NOB74_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HCI1220517.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            15124..15426
                     /locus_tag="NOB74_001321"
     CDS             15124..15426
                     /locus_tag="NOB74_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220518.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            15496..17559
                     /locus_tag="NOB74_001322"
     CDS             15496..17559
                     /locus_tag="NOB74_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220519.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            17559..20171
                     /locus_tag="NOB74_001323"
     CDS             17559..20171
                     /locus_tag="NOB74_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HCI1220520.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            20168..22699
                     /locus_tag="NOB74_001324"
     CDS             20168..22699
                     /locus_tag="NOB74_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220521.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            22749..23081
                     /locus_tag="NOB74_001325"
     CDS             22749..23081
                     /locus_tag="NOB74_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220522.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            23082..23675
                     /locus_tag="NOB74_001326"
     CDS             23082..23675
                     /locus_tag="NOB74_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220523.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            23838..25862
                     /locus_tag="NOB74_001327"
     CDS             23838..25862
                     /locus_tag="NOB74_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HCI1220524.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            25862..27061
                     /locus_tag="NOB74_001328"
     CDS             25862..27061
                     /locus_tag="NOB74_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCI1220525.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            27077..27721
                     /locus_tag="NOB74_001329"
     CDS             27077..27721
                     /locus_tag="NOB74_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220526.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            27732..28538
                     /locus_tag="NOB74_001330"
     CDS             27732..28538
                     /locus_tag="NOB74_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220527.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            28560..28790
                     /locus_tag="NOB74_001331"
     CDS             28560..28790
                     /locus_tag="NOB74_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220528.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            29304..29612
                     /locus_tag="NOB74_001332"
     CDS             29304..29612
                     /locus_tag="NOB74_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220529.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            29614..30036
                     /locus_tag="NOB74_001333"
     CDS             29614..30036
                     /locus_tag="NOB74_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220530.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            30056..31645
                     /locus_tag="NOB74_001334"
     CDS             30056..31645
                     /locus_tag="NOB74_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220531.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            31657..31992
                     /locus_tag="NOB74_001335"
     CDS             31657..31992
                     /locus_tag="NOB74_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220532.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            32133..>32320
                     /locus_tag="NOB74_001336"
     CDS             32133..>32320
                     /locus_tag="NOB74_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220533.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        11914 a         4971 c         6318 g         9117 t
ORIGIN      
        1 tcatatttcc ttgattacct gaggcaatga aagacttatc tacttgaatt agggtgaaat
       61 tctcattcaa atatggtagt aaaattaata tatgtgaaaa tcgaatcttg agatagctat
      121 tccccttgag atattcactg atacttctac tcaaatcatt taaattttta taattatttg
      181 tacggaacgt atatatatca acatcagttt tctttacatg agaacttatt ctaaaatgaa
      241 aaagcctact ctcagaaaga attgaaaaat agatactttc agtagatact gaagattgaa
      301 caaaattaaa cttgtatcct tcaggcatag cacttttaac agtctgctgc attaactcgg
      361 ataatctttt gaaagtagta atatattttt taccagcaaa ccatacatat cttttttcat
      421 taagtatgtt cactatctct cctccattaa ttatatttag catcaaatag ttattgtacc
      481 tatattttat cccattcctt ttaaaacaag aatacgtaca aagtaaaatg ttgtaaatag
      541 tctagcaggg atgtatattt tcatgtacca acataatatt taagaagttt cccatagata
      601 tattggactt cctcttttaa aacacaaaaa taaatactac cttatttagg tagtatttat
      661 taaaagttac gtcaattttg attaaaaata tactacttga acctctcatg agtaaagtca
      721 cgaaattttt gggaatagag cgtacttgat atcttatttt ttcactaata gcagtgtctc
      781 ttattcacca agcgatcccc gtagttccta cggttcttaa tttttctcta gactaatgat
      841 tgtatcttta gaccttcggc cataacatgg agcaaaataa aaaggtacta agtcttatat
      901 atcaatcttc gagtaaccga cggttaacaa ccatatcgag cggcattaat cacccacctg
      961 tagaggatga gcgacttttg cctaattatt gttaaaagcc tagtttcatt tgtttagatt
     1021 ggaaaatacg tcctacaagt atctcttttt tttcatggtc gatccgataa aataaggcat
     1081 agcttttgcc gatcacgatc cgatatgttg ggatatccat tccatagatt tcggaaactt
     1141 cctcatgcat agttggaaaa tttttggtta gttctaaagc cttctggatc gcacctacaa
     1201 atctttttat gctggctgga gaaagagcaa gctcattttc ccattcttct attatcgttt
     1261 caaggctggt ctggaaactt ttagaataaa ctagcgtgta ctctttcatc tattcactcc
     1321 agccgtattt tccgaaagct tttaccattt caatttctga aactgttaaa cctttctcaa
     1381 agtcttggaa actttcttca atcaatttgc gatcgtgttc ttttgctatt tgagtagtat
     1441 ctaatatgaa taagttgcct tcttgtttgg cttggatagt gtctccgctt tttaatccaa
     1501 gagagcttgg aaggatcact cccacgctat tgccgatctt tctaaccttt agttcttttc
     1561 ccatgttatc acacttcttt tagtttttga taaataaatt ataacatgtt ataacgacaa
     1621 ttgccaacgg tgtttcttaa gggattccac tccatattat tattggacaa aataagccac
     1681 ttagaacgct gaaaacatat acaaacgata tcaaaatacg agtgaactac tcaccataca
     1741 cttccgttaa catccattta agtaggtatt tttattatat atagatttaa catatgtcgg
     1801 tcggttgatt gatatagcta aagttataac tcaaccgaag ccgattcatc tacacgaata
     1861 aagttgcgag tgttctcggc taattcataa aaattgttat gtgttccata tagcaatact
     1921 ggaataactt tattttcttg aatctcataa gcaactctat acacggtgac cgcatactta
     1981 aatccattag accaattacc tgataaacct ccagtttttt gctcttactt aaatggatca
     2041 atagcaattt catcacaaac ctatagagga tgagtgactt ctgcctaatt acgttaaaaa
     2101 atattgaaag taactctatg tagcaaaaaa tatctagaat ttcatttcct caaaactgat
     2161 cgatattgta tctaaaaata tatactacct aaaataggta gtatatatta aaatatgtgc
     2221 ttttgttaga aaaatcaata cataaattat catatctgta tatgtcattt aggtatttca
     2281 gttatgttat aatagttttg ctgtctgcta ccccggccta atctggcaag gggaggagga
     2341 gatataatga aatacctttt tgattttgtt tttgcaatca agccatttgc agaggtaact
     2401 gcacactaca tctgcaagtg gcttgattgc aaaattgcca aaaaagacag taagcctacc
     2461 agttaattct ataatataga aacgtaaaaa aaaccccatc agcctacacg ctgatggggt
     2521 ttgatgatat aatgaaatac ctctttgtta ctcataatta taccataatt agtcacgaat
     2581 gcaaccaata gaaaaaacta cttagaacgg tagatcatcg ctaataacaa tgcattgtcc
     2641 accaaatgga ttttgtgaag cattaaatac attgttatta attgtcgctg tttttaacta
     2701 ggcctctccc cttctattat aaaagaagat atatattatt tcttaattac ctactacctt
     2761 aaaccaaaat ttaagtacta cctaatttaa gtagtactta aataatctaa aaaatagtta
     2821 tcccaattgt tatgctttta taatacgatt atttgtaaca aaatgaatat tatataatta
     2881 aacactacca tatttaggta gtgtttaatt attagcaaaa caaaaaatat ttattctatt
     2941 ctcttaactt caactaagtt atgctgcaca cctttatata aatcatatgc aactcattag
     3001 ctagacaaac tacaagcatg tagttttatc tgttaattat gtactaccta aataaagtag
     3061 tttataatta acaggtatat atatttaaaa atttaagatt aattttttta tgacttgtac
     3121 aaatttatct gatattctct tattaagaac tacctaattt gggtagttct tattttttac
     3181 attttaagta gtatttaatt gcaatttggt agtttttttt tattatctta ttcctagaac
     3241 ggtagtactt aatataaata taggtagtat ctaatttaag tattaatggt agtatctaat
     3301 ttaacaggta gtatgtaact actttaaagt aatttttttc agattaacac agtagtatct
     3361 tattaaataa gttaatttta atggtagtac ataattatta tatatatctg acattggtag
     3421 tacttattgt attttttagt agtatataat ctattgtttt ctagcctaaa gccttgtctt
     3481 ataagaagaa tataatatat actactgaaa taaggtagta tatattacta gtaatggtag
     3541 tatgttttat atgcataagg tagttcttaa tttatttttt gttttgacac tggtagtact
     3601 taattatctt taattttaaa actaaatttt attcatacgt tcttctggta gtatttaatt
     3661 ataaataata tttatttaaa gtagttctta atgactttaa aggtagtaca taattcattt
     3721 tatttctgat tttaggtagt atttaattaa aaaacagttt taatgcgttt gcatttttta
     3781 tttatctttg ctattttcga aaagagtagg taattttaca taaataaaac aacgtgaaag
     3841 tagaggatct acaatgactg attttaattt ttttaaggcg gatagagttt acaacgaatt
     3901 attttatcaa tttccaaaag tctttattgt ttctgacgaa tacaaaaaaa tgaaagattc
     3961 aactaagatt gcctatatgc ttttaaaagc aagattagag atcgcaatca gcaaacggca
     4021 aatcgatgaa gaaggtaatg tttattttac ttatacgaca aatgaactat gtagcgtatt
     4081 aaactgccaa aaacaaaaag cgatagcaat caaaaaagag ttggaatcct ttggtttatt
     4141 attacaaaag cagatgggat ttaacaaaca gttagggaaa aataatccta atagactata
     4201 tctagcagaa ttaaaagtct cagaaaatga tatctactta ctcgaaaaat ttgatagaga
     4261 gaatagggaa aacgttgata aatcagaggg tatgaaaatc atacccaccc tcgacgaaaa
     4321 atcagacgct gaatcccttg gggctcaaga gggtatgaaa atcataccgt gccaaaacgt
     4381 tgataaatca gagggtatga aaatcatacc agaacttaat aataatatat tagacactaa
     4441 tagacacaat atagacactg aaaaagaccg cctacaagat caattgttgt tagacaattt
     4501 tgagacaatt atgacaaacg acagcattgc tacgtttatc cctgaacgag tattaaattt
     4561 aataaaaaca ttttcttcaa gttacagtga agctcaaaaa actgtccaga ctattcataa
     4621 tgcaaagaaa aaagccgaaa cagaaagtgg tatttcaata atttttgaag aactcgatag
     4681 ttattatgtc aatgcagaac aagaattata cacgacactg ttaaaagcct atcaaaaatt
     4741 aaaaaccgaa aaagttgaaa atatccagaa cctgattttt gtctatgtaa aaaattggtt
     4801 tatcgaaaaa ccaatagctg ctaaagtatc aagtgaaaaa cgtttgaatt ctgaaagctt
     4861 cccaaaaact attacgaaag actggttaga gtgaaatttc actgacaaat tgattgttgc
     4921 ttcatggagt agcattaaaa ttaaaaattt tttattattc taattatatt acaaatgtta
     4981 caaagaaata gctattttaa tagaatttat gagttaaaat attatgataa aaatcacaaa
     5041 cgtagctttt tacgtcataa gtgttaatag ttaataatta gtttccaaca caaaaaagag
     5101 aacaaacgtt tgcatgttgc tgttttttag ttataataat acgcgaagag aggtaatttc
     5161 attttttaaa aaagctaaaa accttgatat tacttctttt caggcaatac gaatattatt
     5221 cgcttacatt tttttgtata aatttagttg ttttaaattt aattgtctgc tacgcttgtg
     5281 atgaattaat tttcgttctg cacttttgga cgataaattt ggacaattga aaatacaaaa
     5341 aaaagaaagg ccctgtgaga ctcggaaggc tggtaacctt cgtcgacgtc cacaggtggc
     5401 attaagacaa cctttaatcc cttaatgcgt ttacctttca gtgttacggt attacccgca
     5461 acggatttag tataacagat attcaaaagt gataccactt tttttggctg tgttaaggtt
     5521 aaaaatacgt gatattacga tgaatctatg cctaagcata atgttataaa aatgtccgtg
     5581 tggctctttg ccgtatgacg aacgctgaaa ttagagggaa cgcatgtttg gatgcgttcc
     5641 ctcttttttg tttgtcatga acgaaaatca attctctatt tttgaaaaat aacaagaaaa
     5701 acttattaaa aatatttaaa gtaagtgggt ggattatttt atgtcatata caggaatttt
     5761 gagtctcgaa gatatttgtc actacggtaa acggtgtacc gctacagaga aaatcacgaa
     5821 gaaactatca actggccaaa gtaaaaccgt tgtgcagtgt aagaaatata taatccagaa
     5881 agacaaagtc tcagaggaaa tgatttatta cgctggtaaa caaaagcaaa taattttaaa
     5941 agatcctatc cctttaaaag aactatatcc aacaatcaaa catgtttatg accaaaacgg
     6001 tgtactgatt ggtcgaagaa aaaatggagt cttgcgttgt accgcaaaag ggatggggcg
     6061 tttaatcagc tgaattgatc attctcataa cttgtatttt atcgtttttc gcttgcttga
     6121 aaatattgtc gagacttcta aaagaactta gaattactag aaaaataagg agtagacttg
     6181 atctatcaac aattcctttc ggggggtgac ggggtaggtt tttacgattg gtaacgtaaa
     6241 aaattggtca atcgagtaaa tgcccttgtt tggatagtgg tgaaatgaat ttgtgtaaat
     6301 aatatgcaca gagtaaacaa gagggaattt agaagttaga caagttagaa tagcgcctag
     6361 attaatcatg agcagctact aagggatcta ggctttgacg caaactcatg gaataaggag
     6421 taggtcttct cgtaatgggg aggacgcaca agaaattgtg tcgtgtgctg cagtacatgt
     6481 agatacttgc gaggacgttg gtcattggat caatcgagca tttaccgatt tctactaggg
     6541 tttctcgttt cggacgccat aaacgagtcg atatttttta tgtattttta agtaaacgaa
     6601 aaacgataaa atatgaacga gtcctgaata aagtgaaaaa attgatataa aacatagaga
     6661 aaatgaaatt tacgtaatgg aggaatgaca aatgaaaaat tatgatccga atatacgatt
     6721 gggcacacat actattaagg tttctttcca acgttgggat tacaaaggat ttgtgacgtt
     6781 tagaagaggc ggaaattgta aaggattaga tgttttagca ttagacgagg atgatttata
     6841 ctatcaaaaa ttgactgata atccaattgg attcggcttg ctacctgaag atgatgaagg
     6901 taatgaatgg tttaaaatga cgcttacgaa tgataatgga gacgaattat ctgttgaaga
     6961 tacttggtca tatttgagtg attatattgt cagcgttgaa atcattgaat ttgtagcgga
     7021 taaagaagaa taaaaactgg aggaataaat tttacagata aaggcttaga agaagtcacg
     7081 acgaataata aaaaggtagt attaccttag gcattgagta aggaattcat ttaggaggaa
     7141 aattagatgg cgcgaccagt tttagaggcg atggatatgg atactttgac aaaaggaagg
     7201 tatgtacagc tgttagctcg tggttattca cctaaagatg tattcaaatc cctgtctaaa
     7261 ggaacagata tggaaaaaga aagattacga aaagaattcg attattggag aacccataat
     7321 ggaatcaagg atttgaaacc agcacggcca gtaattaaac gaaagaaaaa gataacccaa
     7381 gactgaagtg tagagcgtat gtgatcatag gcttttttat ttttgcaaaa aacaaggaag
     7441 gtaggaaaac tcatgaatta tgaagaaatc gaaaacagaa aaaaagtgtc gaaataaatg
     7501 gaagaaaagt tgctaaaaac gatgaaacaa aaacacctta aaagattatc tgtcatgcaa
     7561 tatatcaatg atatgcagat aacaggaaaa gagaaagctt gtttgttagg ttcaatgaaa
     7621 aactttgaac agttgagacg aacttatgtg aaaacaagtt ctaattgtca actattgtta
     7681 gaagtctcat gacattcatt aatagaattc atttttaaaa ctttttctat ggaaatgaga
     7741 aaaagatttt ttgttttgtc tgaaaggggg tagctggatg agaaaatggt tatttggttt
     7801 tttaggagtc gctttaatcg tcttttgcag tgtgtttggc tatgttagct accaaaaaca
     7861 tgaaggagag gtgtttaagc aaaatataga aaaaaagatg cccgtagatc aaatcaatgc
     7921 acatgcaaag agttataagg aggatgcaac gaacgtcaat aatgatatgt ctttggggca
     7981 aatgttgtcc atacaacaag aagcaatcga aatgggcgtc aataaacaag tatttgcaca
     8041 aattcagatt cctgcacttg gtttagcatt gccaattttt aaaggggcaa atcaatacac
     8101 tttgagtctt ggagcggcta cttattttta tgaagatgct gaaatgggca aaggaaacta
     8161 tgtcctagca ggtcataaca tggaaatgcc aggtgtttta ttttctgata ttcaaaagtt
     8221 gtcattaggg gaggtgatgg acttagttag taacgatggc gtctatcgtt acaaggtaac
     8281 gcgtaaattt atcgtacctg agtactttaa attaatcgat ggcgttcctg aagagaactc
     8341 tttcttgtct ttgccaaaga aaggagagaa acccttatta acgttgttta cttgtgttta
     8401 tacgtcacaa ggaaaagaaa gatacgtggt acagggagaa ctacaataac aaggttttaa
     8461 tcaacgtgag tcgttgaaat atgaaatgag gagagtaaaa aatggcaata aatcggtatg
     8521 taaaaaaagc tggaatgctt attggaatgt taggaatcat tgcaggctgc tttcagggat
     8581 atcgagcata tgcagaagat gtcacgcaaa aaacgccacc agagaaggtc aatatcacgg
     8641 ttcataaatt aatgtacgat caaggaacgc aattgaatgt tgatattgac gggatcaaaa
     8701 acgatggtta tacgcacgat caatatccta caggtgtaac gaaatacaac aaggcagatt
     8761 atggtgatgt tgagtttacg ttaggaaata ttacggatca agtattaccg agagaagatt
     8821 ctgatctaac caacgcgaaa gtggacgaga ttgtacaaga tgtagaagac aagggatcta
     8881 acagtgagta cgtcaagaat gcaaccaaca aaattacttc agctgtagat gaaaatggtg
     8941 agatcacttt tactgatcaa ccagcctatg tcaattccaa agggaatgta tatgtggttt
     9001 atgaaagtaa atccgctgct ggattagtca cacaaaaagc aaaaccaatg gttgtgattg
     9061 cgccaatgac agataaaaca ggatcaggat ttttaaaaaa tattcatttg tatcctaaga
     9121 acattgtttc taagttgagt tttgaattaa cgaaatttgg tgacgatggc gcagaccaaa
     9181 gcaaacaaac ccttttaaaa ggggcaaaat ttgagttata caagggcgaa cctggaaaag
     9241 gaacaaaatt gggtgatctt gtatcggatg atcaaggaaa gctgactgcg actgatttga
     9301 cgttaggaaa atactatttt gtggaagttc cttcggaagt tgtagtggga tcagatcaag
     9361 aaccaacagc agatcaatat ttattaggcg cagacgctcg caacgatgcg cacaataaat
     9421 taacctttga aattacgaat gatggcgtga caagtgactt aaaagcttca tacgtaaact
     9481 ataaagcacc agtgatcgat aaaacagtaa caaatggaac aggacaagaa cattctttcc
     9541 aaattggtga cgcagtaaat tatcaaggaa cgattcatat tccaacagac attgcaggtg
     9601 gcgcagacgg tatcacagta aacggtgtga aaagtgaaac ttctccttac agtgtattta
     9661 aatggggaga tacagcagga cagggacttt cttatgtcgc tgctaaagca aatatcaaag
     9721 taacaaataa agatggatct gtggtattaa aagaaaatac agattataaa atccaaaatt
     9781 cagaaaatgg ctttgtgatc gattttatcg tgaataatgg ccaagtaagt gatactgtag
     9841 caagtttaca cggacaagat cttcaaatga cttataacat gtatgtaaat gacagcgcag
     9901 ctgttgccaa tccattaaca aatagcgtgg atttcgttta taacaacaat ccatttaatc
     9961 aggaagaaca ccacgaaaaa acgaaagctg acgttgtgac ttatggtgca aaattcttaa
    10021 aagtcgatag cggactattt ggaacaggaa tcaaagcaac accgcttgaa ggcgcagaat
    10081 ttgctgctaa aaacgcagaa ggaaaatatt atggtggatt agttgatacg gataaagacg
    10141 gtgtcaaaga agcagtatgg gtagacgatg tagcaaatgc agcgatccta aaatcagata
    10201 aagaaggtca ctttgaaatc actggtttaa ctgaaggtga atattcactg gaagaaacaa
    10261 aagcgcctga aaactatcaa aaattaacga aagagatctc tttcaaagta gacaaagatt
    10321 catacaaaga agaaaaccga atcacgatca aaaacaatca aaaagcttcc gtaccaatga
    10381 ccggtagcaa cggttttcaa acgtatgtat taatctcttg cttgttgcta ggagcagggg
    10441 cactttctgc agttgtttac tttaagaaga aagcctagaa ggatcaaaac caatgattat
    10501 caggaagcct aagaaaaagc gaatcatggg taaatggatc attgctttct ggttactttc
    10561 agctgtaggt gtcttacttt tgatgcctgc tgaagcgagc gtggcgaaat accaacaaaa
    10621 tcagcagatt gccgcaatcg atcgaacagg aacggcagca gaaacggatt cttctttgga
    10681 tgttgctaag attgagttag gcgatcctgt tggtattctt acaattctaa gtatttcttt
    10741 aaaactacca atttatgacg gaacgtccga caaaatttta gaaaatggtg taggtattac
    10801 ggaaggaact ggtgatatta caggaggaaa cggtaaaaat cctttaatcg caggtcatag
    10861 tggactttat aaagataatc tttttgatga tttaccttca gtaaaaaagg gagaaaagtt
    10921 ttatatcaaa gttgatggtg agcagcacgc ttatcaaatc gatcggattg aggaagtgca
    10981 aaaagacgaa ctacaaagaa actttgtcac ttacttagaa tcaaatccca atgaagatcg
    11041 agtaacgcta atgacatgta cgcctaaggg gatcaacaca caccgttttc tagtgtatgg
    11101 gaagcgagta acctttacaa aatcagaatt aaaagatgaa gaaaataaga aacaaaaatt
    11161 atcttggaaa tggcttttag gaagtactgt ttttctttca gtcatgatca ttggttcgct
    11221 atttgtttat aaaaagaaaa aataaaggag ggtaaccaac atgagaaata gaaaatggct
    11281 atttgtttgt gcagccgctc ttttttcttt cactgcctac acacagttga cgtttgcaga
    11341 cagacaagaa agcacggata gcacagaaca aacaatccaa acgtcagata gcagcacgat
    11401 tcaaagcagc gatgaaaccg tcgattcgtc aacagttgat tcttcagaag aacctaaaat
    11461 tgctgaagac gatcaaatag tcaaacagac cattcacgtt caaaagatta tttcttcaga
    11521 acaattagac aaccaggggc atgaaaaaca agaaggagta aatggcgcga agttttctgt
    11581 ttatgatgta tcggacattt tacaaaagat ggatgttaag gatctcacta ctgaccaaat
    11641 tgaatcccaa ttaaaaaatc gagtgaaaaa actatccagt gatcaattga agctagtttc
    11701 taatgaagaa acaaagacaa ttgatcaaca aacaggtgtc tttgaattct cggtagaagt
    11761 acaggcaaat cagaaacaag cttattatat tgtcaatgaa tcaagtcctg aaaacatttc
    11821 taatagcgag gatattttgc tattaacacc tgtttctgat aaaaacggtg aattcttaaa
    11881 ggatgtgtgg atctatccta aatcagaagc ttcgcaacct aaagaagaag taaaaaaaat
    11941 cgtttctact ggcgtaaaga aaaacttctt tgagaattgt tgggattttg ttactcactt
    12001 gttttctaga gattaaggaa gaaataaaat gaaactgatc aaattattat tattcaattt
    12061 ttcttgttta accgcagtct ttttgtactg cggtttatta ttttctaaac tatctatttt
    12121 gccaagctac caactatacc taatgaggat tttaaacata ccagctgctt ccatgccgct
    12181 agatattatg gaaaagctca ttaggaatcc attatttact acgatcaatt tgatcgttat
    12241 tgtcggaatt tcactagtca tttataaaaa agaggggatg aagggatgaa ttttaaacac
    12301 tcgtggacaa gacggttaaa atatgttttt cccataatga tgatgttagg tacattgttt
    12361 gggttaaaaa cagccaatgt ctttgctgaa aaagttattg tcgatccgtc aaatccaatc
    12421 cagaacgtaa agaataattt tattattcca aaagatgttc ctaatgcaaa aacaaatatt
    12481 actgtaaacg gagcgtcaaa agtttacaaa tatcatgttg atgccaacaa aggtggtttt
    12541 acagacgact acgtaggatt agtggaggga aacaaaaata tacgctatcc ttctttccaa
    12601 aaagaatacg gtgaaacaaa ccttgtttta gaaggcgtaa caaccaacac caaagtcaat
    12661 attgactatg gaaaaatcgg tacgtataac gggaaaaaag tcaatatcaa gctagttcta
    12721 tctaatattc acttatactc ggatacgttg ccgtggaatc tactagataa caactataca
    12781 aaaactcatt ttcgagacga tggctataaa aatacgaatg gtgcaatgag taaatctaaa
    12841 aaaagaacag tactttggat ctcagacaat cttttctcag gaattgttta ccattcaaca
    12901 caaatgaatg tgcagctagt agccacatat gaggacggta gccccgttca attttcagga
    12961 gatacattta tcagttttaa ctctttgaac cctgcaggag gaaaaagcac ggatcttaaa
    13021 ggagaatatg cccactatga caaaatgaat acgacagatt ggtatgtcag aaaagatacg
    13081 gttctttcag aatttaaatc tttctacaac aatctgaacg tggtaggtgg ccacccagga
    13141 ggaagctcta agctgacaca agcggataat gatttcaata atttgcatga taaattagga
    13201 gatccgaagt ttggtcaagg tactgtgtcc tttaaaatat ctgaagcaaa tccgacgttt
    13261 gtgattggtt cttctaatgt tcaaacctgg tttactttat cttctgcgac aatctttagt
    13321 gttgttcctg atcaacctga aaaaacaggg gttgataaaa atggaaataa cgtgaacgat
    13381 aaaatgttgc aagtaggaga cacgattcaa tatcgaatca aacagaaggt gaatcgatta
    13441 ggagtggatt tactagcggt ttacgatcga tttgagttaa tcgataattt accaaaagaa
    13501 gtaaattacg tcgatgcaca cgttgaaagt ggtacaaata aaaaattcga tgtatctggt
    13561 gaagtgacct atgacaaaac aaaacaccag gtaaaatatg cagcgaaagc tgatacatta
    13621 aaaaatcgaa tgaagtataa cggcgaaact tacgaattag tgatcaatgt aaaagtcaat
    13681 gaattggcca atcaaaatag tgtagccaaa aatcagggaa cgtcgatcat taataaagta
    13741 gaaaaggata caaatatcat taccgtttat ttccctaaaa ttccagtgaa agaagtacaa
    13801 caaaatggaa aagatgtaaa cggacgaaat gacggtaaga agggtacgcc gacagctcct
    13861 ttaaacgcag gatctgaagt acaatatcta gtcacacaaa aatggcacac aaaaggcgta
    13921 gacgctgcgt cagatcacta caaacaattt agtattcaag atccaattga agctcgtttg
    13981 acatataaag aaggttctgc gcaagtaata gataagagta aaggaaaaga tattacttct
    14041 gaaggcacac taacctatga tagcaattca agaacgctga agtgggaagc ttccgctgac
    14101 ttcttaagta acaatctttt agatggacga gaaattcagc tgatatttac agctaaaact
    14161 ccattacaat cagaaaaaaa tattgataac caagccgtag tagcagtaga taatgtttct
    14221 aataaaacaa atgttgtgac aattggggtt gatcctaact tgccacaggt cattgttcct
    14281 aaaacaggtt ctacacattt agtaacgatt tcagcggtca gcttactatt acttgtgtta
    14341 gcaactttta gttatgcggt tctgagatac atttaaaata aaaaaacgaa agaatgaata
    14401 aaatgaaaaa gttaataata gtagttactt ccttgattgc catgattgtt attttagtcg
    14461 gatgtagtaa tgaaaaaaat aaacaaacta atcaagataa tggcgtattg aaatcaggaa
    14521 ctatgtggaa agaagaagta ggtggtcttg tttataattt gaaaattata gacgagacta
    14581 cctgggaata ctctgagagt gtatggcatc cagatcctgt acaaataaca gtcaagaggc
    14641 aaaaagacta taaaggttta gaaagataca aaatagtaga ttcagctggt gttagggaat
    14701 ttataaacaa atctgattct ttatttattg ttgttcccta tgagaagaat ggcgtaaaaa
    14761 aaataatttt tcttggatct agcaaggatg aaaagcgaac gaaagagaaa ttgattcacg
    14821 atggatcaca atccaataaa tataagttac aaaagactag cgagtgattg ctagtctttt
    14881 tatttgtcct gaaggaggaa tcacagtggc aaaagctaaa acgccatttg aaaaagccgc
    14941 gtctaaaatc ttagaacgcc gcggtgtatc tgaaacacag tggaaacaag aagtccttga
    15001 aaaagcacaa tttgacctat tacggggaaa agacaaggac ttagaaggat atatctatca
    15061 acgtgaacgt gaaaagcttg ttttcgatga aattattaaa cactaaaagg agcgaacaat
    15121 tttatgtttg aatcaattac aatgaatttt ttaacacaac cgaaagtagt agctgcggtt
    15181 gatattttta gagcattaca aactgccgca actagtttaa aaaacaatct gatgattttt
    15241 gctgctgctg cggccgttgc ttccattgtt attgggggtc ttttcttcct atttggacga
    15301 agaggagctg aaaatgggaa gatgcacgta ggctatgtat tgatgggggt aggagttatt
    15361 ttagcagcag cttctattgt ggtttcgtta tttggattgt ttggacaaac acctcaagga
    15421 ttataagaaa gtaaaaaagt aggagtaaga agtagtcgat actttttact ccttttttat
    15481 gaaaggagaa tactcatgta ctttacgatt gcaggcaata ccaaaacaga taaagagtta
    15541 ataaaaaaag caacgaagga agtaggaaag cgtacttctt ttttaccgaa aacaattaaa
    15601 tattctgtca ttgaaacgga agaacagcta catgtgttag ggaaagtact ggaacacgaa
    15661 agtcgatctt ctgttaagtt gactctcacg ttacatgaca cagaaggaaa aatagagaaa
    15721 gctggtacag aatacgtttt tggcccactg gattatcaaa tttcagaagg tttctatcct
    15781 acattgatgg atttaatccg ccttgatgtg tttaaagaaa cggatgaaac tatgagtgtg
    15841 gaagagtctt atcgaaacga aaaactttta caagttttag aagaagagtt agagagcgac
    15901 caaagaaaag tgaatcaagg gagtgaagtc gaagtaaatg aagaagtacc atgggaacga
    15961 ccaatatttc caaagaagga gtcaaaagaa aaagagacag tctatgttga cgaacaagct
    16021 gatattccga ctcagaaatc gatatttgag gaagagaacg atgtgatggg tcaattggag
    16081 gtagatccct ttgaagaaac aatggaggat gaagagacgg ccgaagtaga agttgatcca
    16141 gttgaagcga atgaagagtc aacatggact gaaggggatt ctcaggaata tattgaacca
    16201 cttatcagtg aagaagtaga aaaaaacgaa atagagatac aaaaggcaac tgtatttgat
    16261 tatattttgg atcaatatcc gccagagcat gaatggatga aagaaaaaaa caaattattt
    16321 ttaaatgagc tttattcgaa atatcaatta ccccaaacct atcaagcatt tttagagagt
    16381 aaagaagaat taatctcaca gggtaaaggc acacttttag aacagttaga gtctgtccaa
    16441 tcaacaaatt ggcatgagct tgcacaagaa gatttattag ccacctttga agaacgtcaa
    16501 caagaaacag atcaagaaat taatgagtat gcgacggaac agtcgtctaa ttgggagaaa
    16561 gcaaaagagg aactaaataa agaagaacag cgagtgattg aagaagaagt acaaaaaatt
    16621 aaagagcgat acgaaaagaa acgcgacaat gcgtattcct tgtgtgtagc aaagatcaat
    16681 aattttactc agacgaatca agaagcgtta tcgaaagaaa aagaaaactt gttaaaagaa
    16741 cgtattaaag aacgaaaaga agaattttac cgaggtttgc gtacagataa gctaaagatt
    16801 agcaaagaat taaatgaaca actgaataag ctatatcaaa caacgactga agttcttatg
    16861 gaaaaatacg aaaagatcca gcaagaatta caagtgcaaa ttccaaaatg gaaaaaagag
    16921 tatgaaattc aacaacaaga attgaaagaa caagaagaaa aacaacggca aaaagaaaaa
    16981 gagcgcgaac aattagaact aaaaaaacgt gaacaggatc ttgcggaaca acaaatggca
    17041 atagaaaaac aacggttaaa ccaagaaaag gaaaaagaag cagctgctcg taaggaacgt
    17101 caagaacaaa tggatacatt gcgacaagct cagttaaatt atctagcaca acctcaacca
    17161 acgccttcag tagctgctgt tcaaacccca atgaacaacc aaacaaatct aactccttca
    17221 ccacagcgtt cctttaacgg atggatggtg ggatgtattg caagtttaag cttgcttcta
    17281 ggtggaggaa cagtatttgc ttttaatcat atcaatcaat cttcacaggc tgattctgtg
    17341 gccacaacga cgtcaatcaa ggaagaagcc caagaacaag caagaaaaga gtatgaacaa
    17401 caattagaag aattattgaa tcgtaccaat cagtcaacaa cagagtcaag catggaaaat
    17461 agcaaagaga gtgattctag taaggctaaa gaaggatcaa gcgattcaac tgtacaatca
    17521 aacacttccg aaagttcaga atcaaatgag gtgaaataat gcgtgttaga gaaacaacga
    17581 agcgaaaaga caaacgattc aatttagaaa agaataggta tctttctcat ttctatcgct
    17641 atactccctc aggagaagag ctaccagaaa aacatgacaa acgcatttcg aaaaagattt
    17701 tttatagtgg acttgtatac ctccctttag agtatttagt aacaagagta ccagaagttt
    17761 tcaaccgatt ggaaattgtt aagggaagct tacaaggaat aaatctgttt caattacagg
    17821 aaatgccaca ggtctttcat tttgattcag ctggtttttg gaatccattt actcctacaa
    17881 ctagtttggg tacacgttta gcaatttcga cagtttgtgt ggttccagct gtacttatgg
    17941 gattgaaaat ggacatgtgg tttcgtcctc tagcagatgg acaaaaaggg gataatcgat
    18001 taatgacctt aaaagaaatc caacagattt atccgcaaat acctgaaaca aaaactactt
    18061 ttccaggtta tggaggtatt ccaatcacac attacaaaaa atattggtac attcaaacag
    18121 atactgttaa tacgtgtatt gttggtacct ctcgatcagg gaaaggtcag attgaagtgt
    18181 tagccaccat tgacaattta tctcgtgcag aaaaacaaag ttcaatggtc gttaatgatc
    18241 caaaaacaga attatatgtt ggtagtaaag atgaactaga agctagaggg tatgatgtat
    18301 atgcctttaa tatcaccgat ccactgcaat caatgagtga taatccattg gcactcatcg
    18361 tgaaatactg gaaacgagga gacatagata ctgcaacaca gttaaccaat actttcacaa
    18421 atacgattta ttatgatgcc aacgcttcag ataacaaata ctttaacgaa aacgcgcaga
    18481 aagctgtcaa tgcgcttatt tttgcgttgt tagaacaagc tgatcaaaca ggagattact
    18541 ccaaattgac accgaataat ctcgttgagc ttctttctga gattggcggt tttaattatt
    18601 atccagatcc agacaatgaa ttcaaacagt tgaatgcctt agatgaattt atgaatcagt
    18661 tgccacctgg aaacattgca aaaaaacaat atggggcaac gaaaattgga tctgataaag
    18721 cgaagggaaa tattttatca acggcaatca cgggattgaa tccatttact ctaacgaaaa
    18781 ttgcaaagat gacttctcaa tcaacgattg attataaatc ggttgggttt ccaaaatact
    18841 tagatttgaa attacatgaa agtcttttaa atcaacgagt cgtagtagaa ttttatcata
    18901 agggaaagaa atttcatgaa gaacgtgtca aagtaggcta taaaggattt tgtgaaatca
    18961 attttgattg tcatttagtt gcaggtgatc aagtttgttt aaaatacgat catcaaggaa
    19021 aagaatatgt ggcttggtat gaattttctc aaagagtatt gaaagacgaa gagggtaata
    19081 tcgtttatcg gaaaaaacga ggagaaaccc atttgccaga attagaaaaa gaagccgttc
    19141 taacattaga tgaggagaaa agtaacttat tagtagagtc tattcggatg cactataccg
    19201 ataaaccaat ggctattttt atgcttacac ctgattatga tccatctaac catatcattg
    19261 ttagtatttt tcttagtcag ttatataaag aattatctac gcaatgtgtt aagactaaag
    19321 gagataaatg tcaccgcagg attcatttta ttttagatga atttgggaat atgccaccaa
    19381 tggataatat ggaaggaatc atgacggtca cagctggccg aaacatgttg tgggatctgt
    19441 ttattcaatc ttatcagcaa ctttatgcga agtatggaga acaaaacgca gcgattatca
    19501 aagaaaattg tcagacacat atttatatta tgtcgacaga tgataatacc atcgaagaat
    19561 tttctaaaaa agtggggaat aagacggttg aacaagagaa cagtaccatc aattcattag
    19621 gtatgaatac tcatatcaat cgcaatgttg attcagatcg tatcttaact cctgaaagaa
    19681 tttctacttt tttagaaggt gaaacgattg tactcgctcc tttaaaacga caagatttga
    19741 aaggtcataa aatacggccg tatcctattt ttaatcatgg ggaaacgaat cttccttatg
    19801 cttatcaata tattgaagat ttcaatccat cgtgggatat caatgatata gacatacatt
    19861 gtacacatgc ggacttggat cttaaggctt tacaaattga ttatgattat ttcctaccag
    19921 atgaatatgc tagaaatctc tatcatggac tgcatgatca attagaagaa aaaaacgaag
    19981 aaaatatgtt ttataaaatc gttcaatctc ttgagaatga gacggctaaa aaattgttaa
    20041 ttcaatttta cgaagaacaa gcagcagatc gacttcaaga atatgttgaa aagttgatca
    20101 aaaataaaga aatttctgaa atgattggga aacggttgtt attggaatct gaaaaggtgg
    20161 tgaaagaatg atcattggag gaattttttc tggcatagcc gactggtggt caggcttatt
    20221 cggagaaggg gatgcaaacc ccaaaaccgt aacgaaagtc ttacaagatt atggtaatta
    20281 tctgcagtat caagatgtat ttagttggat ttggaacact tttctgtggg gattgattaa
    20341 aggattatat aatctcaata ctttactaga aaaaaccatt tatcaaagct ttgatttaaa
    20401 agacttattg aacgccgctg gggtaaatgc actatttcaa agtttgatta gtaaggtatt
    20461 ggctcttttt tgtgtcgtca cattaattta tttaggcttg aaatttttta tgagtaaaca
    20521 cccaccaaaa gtcaaaaata tcttggttaa tttatttatg gccatgatct tgatttttgg
    20581 tgggagttct ttaatcgatg aagggttaaa tatcagtaaa agcttttacg gagacgtcac
    20641 tgcagcaaat aaagcagata aaacgggttc acctgctttt caaattattc aaaataatgt
    20701 gatcgatgtc agtacattac tagcaactga cccgaataaa gtagaatccc tgccaacaga
    20761 caaaagaaat gctttaacag cgaaaaattt taaaacagcg aatatcaatg ggattattac
    20821 tcctaaacaa gctaaagaaa tggcggataa agataagagt ggtttatcag atttacaaaa
    20881 ggatcggtta agagcgttac aataccgatt ggaactagat gataatggga aagaaattcc
    20941 tgttcaaatt agtgacgaag gcttagcaaa atatgtctat acttcagggt atcgtcgata
    21001 cagtagtaaa ccaggtatta tcttagctgg tgaatcttct ttggcggtgg cctatttatt
    21061 tatcctattt acgatcgtta cttgcattat tgagctggta tttaaaaaat tctatttagt
    21121 gattgccgcg tcaacggact ttgagacagg ccaacggatg aaaagtgcga tagaagatat
    21181 ttctcaatcc ttcttgttat tggcgtttac gattttagaa ttacgaatct atacattaat
    21241 gctttcaggt atcggtgatt tgcatgcggc aggaaagatc aatggattct tgtatgttgt
    21301 tgctttaatt gtgctaacta ttgcgctatt caaaggctct caatcggtta cgaagatttt
    21361 cggtgttgat acgagtctga aaaacggcag taattctctt cttagcatgt ttgccttagg
    21421 aaatattgcg aaaaatgtgg gtagcggagc taaaaacctt gcaagtgctg gtaagagtgg
    21481 tttaagccat ttaaatgata ttcgtaaaaa tggatttggc catcgaaaag atgttacccc
    21541 tgataacggg gaagaacaat cagacgataa agctacaact gtacctaata gtaagaaaac
    21601 agtttccgaa atgttcggga aagcgaaaaa tggtgtttct aaagccgcag aaggtcttgg
    21661 ttacgtcaat gaacgtgggt taaaaggaac agctgaagat cttacagaaa aagccaaaga
    21721 caccttagaa gagaaattag acggcacgag agctaaagaa ttggctgaag ctgtgaagaa
    21781 tccatccgaa gcactagaaa aacaaaaaga aaaagcttca gaagtcaaag aaggactaaa
    21841 agatgcgtat ggtgaaggac aagttaatgc agcagtaaaa gctaatacaa caaccgaaaa
    21901 agaaaatcaa gaaggtatag tgattccttc agtcaaagat caccaagaag cgttgcactc
    21961 taatgaaaat tcgattgaag agaaaaattc catagaagaa agaaattcag aagaaggaaa
    22021 aaatggacag ttaccaaaaa ctgatccaga acaatatcgc tataaaccta acagtgacct
    22081 tgaaaatgag aagcgaattt cagatttatc aaaagtaaat caagaagaca aagcagaaaa
    22141 tgagggacag ttaccaaaaa ctgatccaga acaatatcgg tatagatctg ttaactccga
    22201 aaatgaaaaa cgcatttcag atttaccaaa acgaaatcaa gaagtacaaa cggatgagga
    22261 ttccatcgtt ctgccaaatg ataatggaat cgaagttgga actgaaaaat caacgaaaat
    22321 tggtttacct aaggcacaaa atttaccaat gaaagatagt cgtttgaatc aattcaagga
    22381 gaatgatcaa agctttgttc accaatcaac tgcaggtact gttcaaatga aaccaagtcg
    22441 tttgcctgaa aatggaaatc tgacaactgt ttcttacaat ttatctgaaa gtggtgagac
    22501 agggaatgcg tccgttcaaa atgttgtgac aagagaagct gcaccaaaac ctattcaaaa
    22561 cgttcataca ggttacaagc cagcaaatgt ggcatttact gcaccaacaa aaataaatgt
    22621 gacaagagaa actaaaaaca ggaacaatgc attgaaagaa caactattga gggatatcaa
    22681 acaggatatc aaaccataaa aggcctacaa gttaggcctt ttatttatat gaaaaggaga
    22741 aatcaattat ggataaatat ataaacatga aaaaccctcc aagatttagt ggagaatgga
    22801 agtttttcgc ttttttcttt ttagatctat taacgcttgg tggctgcttt ttttgggcga
    22861 aaatggtcaa taatcttgtc cacttaccac tcttttttgc actcttgaat tatggcttat
    22921 ggattgcgat agcgttagtg attgtttggc gaccctataa taacccaggt caacgacaaa
    22981 tttttgcgat tatcgagtct attttttttg cggacaagaa ccattatcat gcgttagatc
    23041 ctaaccgaaa ttatcatggt acgtataagg aggatgaata aatgcgagtc aaaggacaaa
    23101 attcagttga aaggaaatcc attttgcagt ttggaaaacc agaagagcgc tctatcttgg
    23161 acttatttcc gtataaatcc tgtacagaag agggagtctt aattactaga gaagatcatt
    23221 ttcaacgtta ttatcgtgta gtttctacag acgtggaagg attaaatgaa caagagaaac
    23281 tagaacgaat gaatcagttg accaccgtca tgcgtacgta tgtgccaaca attaagttag
    23341 ttagtttgac cacagagacg gatctaacgg aacaaatcgt gcaaaagcgg caattattag
    23401 ataaaaatcg tatggaacag tccttaggaa gaaatctaca acgattaaaa aaatatgaaa
    23461 agaaattagt cgaagaaatc caggaattga aacgagcaga acaagaacgt cctgacttaa
    23521 gcttcttttt cgtcattgaa ggaaagacaa tcaaggattt acaaaccaga aaccgtcagt
    23581 taatgcgatc tagtggcatt ttagggttaa aaccactcta caaaaaagaa ttgatcaaga
    23641 ttctgtatcg aatgaacaat atgaatgatg agtaggaatg gagaagagag aatgaaatat
    23701 ccgttgatat ggttagaaaa agatgttccg aaggaagaga ccactagaaa atttcctcac
    23761 actttaagcc tgggtaagtt gggaaaaggg caatctttta accaagtaaa gaatcaaaca
    23821 agaagaggtg actgtacatg ttagaagcaa ttaaaacagc tttttcacca caaaatgatc
    23881 aaaaagtact tgatccatta aagcaactag gaaatcggga aatagaaatt ttaaaatcca
    23941 aagggtatga tttagatttt ttaaaacaag tgatgccaca aggtgggtta aattttgatg
    24001 aagaatatgt gacgtatggt aatggttatt cacgatgtgt gacagtttat cactacacaa
    24061 aaaatcctac gcttttttgg ttggccaatc tcatgaacaa tcctcataca gtggccacac
    24121 tcgatgttag cacagatgaa aagcaaaaag tgattgatca aatcaatcgt gccttagatg
    24181 aattaaatga tcgatcagat aatgaacgaa aagcgactga ccgaaataaa agcgcagaag
    24241 aatacctgga actagcggaa tatgctcgta aattgacttc taatggggaa atttctaagc
    24301 aagtcaaagt gagagtacat gtttacggaa acacgattca agaagtagat gaacgagcgc
    24361 aggaactgat cgaaaatcta aaagggatgg attatcgtgc ggtgacttat ctgcataaaa
    24421 ccaaacgaga ttggcaatcg atgtttacca tgttcgatga acaagctgaa tggttcggaa
    24481 atatcaaagg gcaatcacta ccatcgttaa acattggcgg aggtttcccg ttccaccacc
    24541 aaacgctaaa agatccagga gggacacaat atggggaaac catgacaggc ggcccatttg
    24601 tctggaatgc gacgtataaa aatagtgtac ggttgtctac taataccttg cttctaggaa
    24661 tgatgggagc tggtaaatcg accgttctta aaatgatcgc ggaagcccat ttagctgcag
    24721 gagactttat ttggggcttt gaaaagggaa aagactttat tcctttctta aaggaatata
    24781 acggtattat ggtgcgttta gacggatctg acggaatgat caatccttta gagatatttg
    24841 ccacacggac gtatgatgaa gcatccagtt tatatgacga tggatcagtc aaagatttga
    24901 agatcaatga agcagcgtcc tatcaaacac acttagacaa agtggtctat caggtacagt
    24961 tagtgagtcc tcagctaaaa ggaacgatga aagcagaatt taagacctac ttaaatcgtt
    25021 tttatgaaga gtatggaaca gtaccacgcg gctttacttc ctcaaattcg cgttcaaata
    25081 cggagacgca agtcacaggt aaagatccag aagcttatcc gacgttcaaa gaatttttag
    25141 actttttagg acaactggaa ttaccaggtg cttcccaaga gaaaaagaat cgaaaagaag
    25201 aaatggaatc catcgtagaa tccttatgtg agacgtatgg catgattttt gatgggcata
    25261 gtacgattcg acaccttgac caacaacagt tggtcttttt tgacattgac tctattacag
    25321 gcttagatcg aggggtacaa caatgtcaaa tgtacatggc tatgacgttg atttggaatc
    25381 aggcattgat tcaaggaaga agacaacgac gtttaattaa agaaaaacaa atggaagaac
    25441 aagacttcaa acgcttcttg gcgatgattg atgagtgcca taatgcgatt aatccagatt
    25501 ttattgaaac ggtaaattat gtcacaaact ttcaacgaga aatgcgtaaa gtagaagcaa
    25561 tgactgtttt agctacacaa tccccacaag aaatggtgcc agaaaatatg tcttctgata
    25621 acttctcgaa actgaagaaa gtctttgaat tttcttctac gaagatcttt atgcgtatgg
    25681 atgaatctat tttacgtcat atagaaggat tagtgggtaa atcaatgacg aactcagaat
    25741 tagaatccat tcctcaacaa aatcaaggag acgctgtgat caattttggc tcaaaagaaa
    25801 ccattcgtgt tcattttagt ccgaacaaac gtcaattaaa attgtttgat ggaggaaaat
    25861 aatggaaaac caaaatgaaa gtttaatcaa acagtatgtt aagcgtcgtg caaagcggcg
    25921 cttatttttg tgggtgtttg gtacttctgc aggtttgatt actatattga tcactgtgtt
    25981 tgtgaccctt tttctaatac ttgcggcagg ttctattgat aattctgatt caagtagtgg
    26041 tggcgaagct tttacaggag aatattcgga aggcttaccc atttataaag aaatcaaagg
    26101 aagaggccct ttttctgatg agattgcgca atatgctgta ggtgcagcag tgaagtataa
    26161 attattacca agtgtgatcc tttcgcaata cggttatgaa tcagcgtttg gtacgtcggc
    26221 gtccgcaaga aatgatctca attattttgg gattacgtgg tttgatgggt gtctgtttcc
    26281 taaaggaact gcgcgtggaa ttggtggcat tgaaggtggc tggtacatga agtttcccaa
    26341 ctcaaaagct gccttctcct attacggctt tatggtagcc acacaatcaa attttaatgc
    26401 ttgtgtcgga aataaaagcc ctggcgcaag cttattgatc ttaggacgag gagggtatgc
    26461 cgccgcagga attactgaag acagtgccta ttataaaaat tgtatgtcta ttattaatac
    26521 aaataaattg atggagtacg atgagtttgc gattaaacac tggagagaag gcggcggaac
    26581 tggtggtacg attacaggaa gctggggcaa tccattccca ggaagtagct tagataaaaa
    26641 ttcgttcagt ggaggacaac tttttgggaa aaatccagga ggagaattcc gacctaacgg
    26701 gttccatgat ggactagact ttggttcagt cgatcatcca ggaagtgaga ttcatgcggt
    26761 tcatggcgga aaagtcgtgt acgttggcaa tcctggtatt tcaggtttgg gtgcgtgtgt
    26821 gatcgtgatt aattacgatg gcttgaatat ggtgtatcaa gaatttgcaa atagtacagg
    26881 aaattctcga gtgaaagtag gcgatcaagt gaaagttggt caagtaattg ggatacgaga
    26941 tacagcacac ttgcatttag gatttactcg aatggattgg cgtcaagcac aaggacatgc
    27001 attcattgat gatggtacat ggatcgatcc gttaccattt ttgaatagca gcaaaaaata
    27061 gatcaggaga aaaaatatgg aaaataaaac cttaaaaatc gtcttaacag ctgcaattag
    27121 cgttagttta atcggcaata ttgcgttgtt ttggcagctt aaagaagaac aagagacaaa
    27181 tacctataaa attgaagaag tggctaaaaa cgcgtctgat aagctcaaaa aaaattcttc
    27241 tgaggcacag gcgaagatcg acaagttaaa tcaaaccatc aatgagaaaa accaagaaat
    27301 cgatcagctg aagcaacaag atggcacaaa agcaaaagag gaagtaactg aagcacaaag
    27361 aaagacggca gaagagttcg gtcaattggc cattgataaa tcattaagca gaaatgaatt
    27421 aacggaaaaa ctaaaagatg tcgcaaccca agaagtgatc gacaaattaa gtcctgcaga
    27481 cgatgatcac caacatgacg actacggaag ttactctttt acattaggtg acgtgcaaac
    27541 ttacgctcaa acaagcagtg taaaagagga acaaaatttt gtcgtatttg ttgattatac
    27601 aatcggcaat cctcaattta aagatgtcaa accacaaaaa ataaaaggtg gattaactgt
    27661 cactgaaaaa caagtagatg gtcaatggaa agtcacagac tttagttatt tcactcgtta
    27721 ggaggaagaa aatgagtaag aaaaaaggag caagacaacg ttttaaaaaa cgaaaaagtt
    27781 atcttagatg gctggggatc tttatgattc tcggcttttt gattcttgct agtccgattt
    27841 acacacataa aaaggtagac ataccagatg aagtaagcac gaacgcattt ttaaacacga
    27901 aggaactgac gatggtttca aaagaaaaag gagcgaacca gcaattagtt tttgaatttg
    27961 cgatcgacga tgaagatcag agcttattaa aagaactagc taatcttaat tatcgtgtag
    28021 aagtaaagac agctaaaggg gattatcaag caataaaagc caaagtgatc aaggtgtctg
    28081 atgattattt tgtagtgaag ttagcacatg taccagaaga atatatcgcc atgcgtttaa
    28141 ccattattcc tgaaaaaatt gatccaaaag tggatatgca agaaccacaa gatctgattt
    28201 attacgttca cgaagataag gttaaagatc aagtgaaaga tgaagattat gaacaacatg
    28261 cgatcaatta caaagtgaaa ggatacaaaa aagaacaaaa agcagcacaa aaacaaatgg
    28321 aatccttcca agcaaccatt gatttgaatg aagaattagt gaagaagcta aaagatcaat
    28381 tgccttatca agtcgcagat gatcaggaaa atactgaaaa caagattaat agctaccagc
    28441 aagaaattga aacatcgaaa acgcaaatga aagatcaaga agagatcatt caaaaacttc
    28501 aagaaaaaat tgatcgtatg acaaaagaaa agatttagaa ggacaggtgg agtgaaaaaa
    28561 tgaagcgaac aaacttggct gacaaagata ctttcgctga gcagaaagta ttgattaaag
    28621 cctatctcaa agttgtaaaa gctaaagaaa tatgtcgaga agtgaattta tctaatacaa
    28681 caatatctga gttgaagaat ggtcgaaaga atttagatac tttaaaattc agatcatttg
    28741 aagctctata tgtagctgct aaaaaatatt ttacagctga taacaaataa aaaacaggag
    28801 tattttatgt gaaaaaagta tataaaaaat gcttatgaat cagctatatc accttaacca
    28861 tttgttaatg agatgggaga aaacattaac cacgattcta acgcaaacat caagcacata
    28921 aaacatttaa cactcctcct ttctggctga agatttcaac caaacaggaa gacagcgtat
    28981 caattatagc atacactttt tcttaaattc atttttcata tgacaaaata tttccttcta
    29041 atcgacaaag ttagaaggat tttttattgt ctaaatacac aaataacctt aatttataaa
    29101 gagcataagg aaacgtggga acacttttta aaaaaagtgt tccaataggc tgtgcctatt
    29161 acgtttctca aaaataattg tgggaacaaa atatttaaaa ataggatagt gaaaggatag
    29221 caaaggatag taaaaggata gaagcaggat agcgaaaagg ataggctcct tttcgctatc
    29281 ctttttaaat tggaggaatt aatatggaag taagaataag aaatgtagat gagaaaatcg
    29341 taagagaaat tgatcgaaga tgtgacgaac taagtaaccg aacgggtaat aaatggagtc
    29401 gtaacgatta tttaaagcta ctcgttgaaa atgattttga tcgtcctttg atggaatata
    29461 aacaagataa atttgatcaa ttattaaatc agttaataga taaattttct tttgttcaaa
    29521 gtcataatac aaaagtatta gaagaatata tttgtcagaa taatcaaatt atcgaacttt
    29581 taattgaaca aagtagagga ggagaagttt aacatggcca aagttataga caagcatatt
    29641 tatttttatg aaacacatat agatgttcta gatgaaatta ttgcaactca tgcagaggtt
    29701 aaaaactata gtgaagccgt tcggtttcta tgtatgaatt atgattcaga agtggagaaa
    29761 aaagtaaatt ccaatcaagc aaagttgaat gcaatgggaa aagaaatttc tattttaacc
    29821 gaaatggttt cagagtttgc ggatctccat ttgaaagata cagggatttt aattggtaca
    29881 aattcaactg tttaccaaga agcaaaagag cgtgtggaag gcaagataaa agcaaatcaa
    29941 acgaagaaat attctcctaa gataaagaaa acaataagcg aatcagtgac tacaaaaagt
    30001 gaagtatttg atccaacaag gttcttaaaa cgataaaaat tagaaggaga atgtgatgag
    30061 taaatcacct gcagtcattc tcacttgtca atttaccttg cccaataaaa aatctttttc
    30121 aacatacatt gattatatga caagagaaaa agcgctggaa gaaaaggaac gacgtacgcc
    30181 cgaggaagaa caggaactgc gtctaatcaa gaatgcttta gaggattttt atattcctga
    30241 aggagaaact ttttcggaga gtaagacggg taaagaattc agcgaaacgt cgaatgaagc
    30301 gcaatcgttg atgaaacatg gaatcaattt tgacaagtta gaagaacaag attttaccaa
    30361 atatctttct tatatgacac gtcactatgc gttagaacaa aagaaagtac tgacgcatag
    30421 tgaacaaaaa gaataccaac gcttgaacca agcaataaaa aaatatcaaa cagagccaca
    30481 caaaaaagct tcaggaaatc ttcctggagt tttttctatg gcttcagacg aagtgaaagg
    30541 aagtgatctg aaggagatca agcaaacctt ccaaagagga caacaaaaag gctcaatcat
    30601 ttatcaagat gttgtctctc atgatcattc gtatcttgaa aaaataggat tgtacgatcc
    30661 caaaacagat actttagatg aagaaggttt aaaagcagct ggaagaaaaa tgatggagac
    30721 attgttcgag aaagagcaac tgaatgaaac aggctactgg atggcaacga ttcaccgaaa
    30781 taccaaacat atccatattc attttgcagt tgttgaaaaa aaaaatacgc gtaaaccata
    30841 cactgagatt gaaaatggtg tgagttatat cgtaccgaaa gggaagagaa ggcaagcaac
    30901 attagacgaa atgaagacta attatgtaca tgagttagaa cgtttttctt atgaaaaaaa
    30961 tcgaatgggt atggagaaac gaaatttatt gacacggaaa agtgatttgc gtaacacctt
    31021 aaccaaagta gtgaaagagc cagtacgtta tgatcgacac gcaatgagct tattaactga
    31081 agtatataaa aacttaccta aaaagcgttc ggaatggcat tacggggatg aaaatcgaac
    31141 caaactttca ccatacacaa gagagaaact cgatgagtta acccaatatg tgttaacaaa
    31201 agaacctgga tatcaagaat atatacagat ttcaaaagca ttgaaagaag aagcaaaaag
    31261 tctttatggg gaaagcaaga gagaatcaaa ggatgcagaa aaaaatgctc tctttgattt
    31321 aaaaaagcgc acaggaaatg ccattctaac agaactgaag aaacaggata gtcaaataaa
    31381 acctttaata gaaaggatgg atcagatgca atctatttac aatgaacgat cctttcgaac
    31441 acttaaacag ttgccaacga atgaatacaa atatagttac gaagaattca tgaagcgcag
    31501 gaaacaattc caacaaagag ttgtcacgca acggagtttg cgtcaattaa atcgaacgat
    31561 taatgcccat gaagaaaaat accacgcaag taaagcatac gaagagcaac aacgaagaat
    31621 tcaaatggaa caagaaagac agtaggagga atagcaatga aacaatattt agatcaatgg
    31681 aaagttatag aaggatcatt aagagaagaa cgaatcgaac aacttcccga ttgtttagaa
    31741 aaagagcatt tgtttcagat aagagaaatg ttgataaacg aacagtttga tccaaatcaa
    31801 tttttagtcg ttgagtaccc agctactggt gtgtactgtt gtaatcatgt gaagggtgaa
    31861 aaatatttta tcattcaaga atatgagggc aagttagcgc cttattatac tacttgggaa
    31921 atgaatgaag aggggatcaa taacttcccg tgtaaaagca ttgaagagtc tatttcactc
    31981 acagaatgtt agttgttaag tgaataaaag aagtaaaaga gtcctgaacg tgattgtcca
    32041 ggactctttt ttttcactga attgttttcc gccaattcat tgagtggtgc gatttccgtc
    32101 tacattatat caaaagaaag gaggaagaag aaatggctta ttcaacgatt ggagttgttg
    32161 ttgaaaaaag cagagacaat cttgtttttg tgacagaaat tcaaacaggc agagcttttg
    32221 tagtcacaga caaagcggca aaagcatatc aaagtggcga tattttaacg ttaaatctga
    32281 ctacgaagac gttcgtcgat gcggcagaag attatccatt
//
LOCUS       DAIGWC010000029        32197 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.029, whole genome shotgun sequence.
ACCESSION   DAIGWC010000029 DAIGWC010000000
VERSION     DAIGWC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.029"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(20..1123)
                     /locus_tag="NOB74_001337"
     CDS             complement(20..1123)
                     /locus_tag="NOB74_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCI1220534.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(1345..1815)
                     /locus_tag="NOB74_001338"
     CDS             complement(1345..1815)
                     /locus_tag="NOB74_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HCI1220535.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            2072..3391
                     /locus_tag="NOB74_001339"
     CDS             2072..3391
                     /locus_tag="NOB74_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HCI1220536.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            3832..5472
                     /locus_tag="NOB74_001340"
     CDS             3832..5472
                     /locus_tag="NOB74_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HCI1220537.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            5626..6948
                     /locus_tag="NOB74_001341"
     CDS             5626..6948
                     /locus_tag="NOB74_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HCI1220538.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(7010..7441)
                     /locus_tag="NOB74_001342"
     CDS             complement(7010..7441)
                     /locus_tag="NOB74_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1220539.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(7505..8341)
                     /locus_tag="NOB74_001343"
     CDS             complement(7505..8341)
                     /locus_tag="NOB74_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCI1220540.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(8531..8833)
                     /locus_tag="NOB74_001344"
     CDS             complement(8531..8833)
                     /locus_tag="NOB74_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HCI1220541.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(8859..9290)
                     /gene="ruvX"
                     /locus_tag="NOB74_001345"
     CDS             complement(8859..9290)
                     /gene="ruvX"
                     /locus_tag="NOB74_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HCI1220542.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(9287..9553)
                     /locus_tag="NOB74_001346"
     CDS             complement(9287..9553)
                     /locus_tag="NOB74_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HCI1220543.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(9807..10532)
                     /locus_tag="NOB74_001347"
     CDS             complement(9807..10532)
                     /locus_tag="NOB74_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HCI1220544.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(10898..10968)
                     /locus_tag="NOB74_001348"
     tRNA            complement(10898..10968)
                     /locus_tag="NOB74_001348"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10934..10936),aa:Gly,seq:ccc)
     gene            11085..11837
                     /locus_tag="NOB74_001349"
     CDS             11085..11837
                     /locus_tag="NOB74_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCI1220545.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            11853..12332
                     /locus_tag="NOB74_001350"
     CDS             11853..12332
                     /locus_tag="NOB74_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCI1220546.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(12583..14163)
                     /locus_tag="NOB74_001351"
     CDS             complement(12583..14163)
                     /locus_tag="NOB74_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HCI1220547.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(14156..14899)
                     /locus_tag="NOB74_001352"
     CDS             complement(14156..14899)
                     /locus_tag="NOB74_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220548.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(15075..15851)
                     /locus_tag="NOB74_001353"
     CDS             complement(15075..15851)
                     /locus_tag="NOB74_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1220549.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(16099..16935)
                     /locus_tag="NOB74_001354"
     CDS             complement(16099..16935)
                     /locus_tag="NOB74_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HCI1220550.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(16946..17875)
                     /locus_tag="NOB74_001355"
     CDS             complement(16946..17875)
                     /locus_tag="NOB74_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCI1220551.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            18067..18420
                     /locus_tag="NOB74_001356"
     CDS             18067..18420
                     /locus_tag="NOB74_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCI1220552.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(18494..19150)
                     /locus_tag="NOB74_001357"
     CDS             complement(18494..19150)
                     /locus_tag="NOB74_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCI1220553.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            19376..21310
                     /locus_tag="NOB74_001358"
     CDS             19376..21310
                     /locus_tag="NOB74_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI1220554.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(21396..22619)
                     /locus_tag="NOB74_001359"
     CDS             complement(21396..22619)
                     /locus_tag="NOB74_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI1220555.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(22613..24511)
                     /locus_tag="NOB74_001360"
     CDS             complement(22613..24511)
                     /locus_tag="NOB74_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HCI1220556.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(24505..25623)
                     /locus_tag="NOB74_001361"
     CDS             complement(24505..25623)
                     /locus_tag="NOB74_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI1220557.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(25706..26539)
                     /locus_tag="NOB74_001362"
     CDS             complement(25706..26539)
                     /locus_tag="NOB74_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1220558.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(26532..27449)
                     /locus_tag="NOB74_001363"
     CDS             complement(26532..27449)
                     /locus_tag="NOB74_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1220559.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(27676..28800)
                     /locus_tag="NOB74_001364"
     CDS             complement(27676..28800)
                     /locus_tag="NOB74_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI1220560.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            28983..29891
                     /locus_tag="NOB74_001365"
     CDS             28983..29891
                     /locus_tag="NOB74_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1220561.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            30032..31645
                     /locus_tag="NOB74_001366"
     CDS             30032..31645
                     /locus_tag="NOB74_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI1220562.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         9944 a         6395 c         5489 g        10369 t
ORIGIN      
        1 ttttttcgtc atttgtttct taaataaaac gattctcacg caattttatt tttttgatat
       61 cttctactgt ttgtgttcca gctaattgca tgaccatttc caattctgtt ttaaagaaat
      121 caaacacttg atggactcct gtacttcctc ctaaagacaa tccataaata acgggtctgc
      181 caatagcaac aagatctgca cctgatgcga ttgctttgaa aacatgctgt ccgcgtcgta
      241 caccgctgtc aaacacgatt ggtacacgtt tatctactgc ttctgccaca tattgcaacg
      301 aatcaaacgc tgctggacca ccatctagtt gacggccacc atgattagat acccagattc
      361 cgccagcacc agattctaat gaacgataga catcttcttc tgactggaca cctttcacat
      421 agactggcaa atcagaatga gcagcaataa attctacatc ttttggacta agcttctgtt
      481 tggaagattt gtacacagca tccatcgttt ggcctactcc tgattgataa gcctgaacga
      541 tcggcattgg cagtgggaag gtaaacccat ttctgcggtc tgtttcacgg tttccgccaa
      601 ctgttgcatc cgctgtcaat acgattgctt ttgctccatt acgcttggcc acttcaagaa
      661 tatccaaatt gatcccatca tctttgctca tataaaattg aaaccattgc ggtgctttct
      721 ccccgcctgc ttctcttatc tcttctaatg tacaagaagc gtaagaactt gctgtataga
      781 tcgtcccaaa atctgctaca ccttttgcag aagctttctc cgccttcaca tgagctaagc
      841 catgagcagc aactggtgcc atgatgattg gtgcagtcag cgtttctttg tcaaaatgtg
      901 tagttgtatc gggtaattct acatctctta atacatgagg aataatcagc tgatgattga
      961 atgcccgttc attttcttga taagtaaata agtcgccagc accactgctg atgtaaccat
     1021 aaccaccagc tggaatcact tgtgaagcgg ctatttctaa atcttccata ttgataaaat
     1081 ccactattcc ttcatttgta cctgcttgat acgttttttc catttcaatg ccttccctct
     1141 ataaaaaatt gaatgaataa tatgatagcg tttacacact ttatattact cttccgtatt
     1201 gatacaggca aataatctgt ttacatttca gtcattccag ttgttactac tctgaaagaa
     1261 atgtttagaa cacaaataga taaaaaacga tgggattttg acaaaagtcg tgtcaaagtc
     1321 ccttttacga aatactgtgg atgcctattg aaataagtgc gggttgtttc tttgtatttc
     1381 aatcgtttct tgccattctt cgtttaattt tggattaccg ttttcttcct tgaacgcata
     1441 aggtcccaat ccaaaaagct cagttagtat ttgattcacg attccatata gctcggtgtg
     1501 atcggacaca tgattattga agatcatctc attatcacca cgtttgaatc tcacattcgg
     1561 gctctcatga tgaacctcta tgcagttttc cccttttttt aactgacgga tttctgaaaa
     1621 catctcataa atatcttctc caataaaacc ttcagcaagc gccagactgt ccacaagacc
     1681 gcctactgtc aactcagaga ttatcgcttt gttggcacca agctttaatg tatagcttgt
     1741 tgcttctact acgccgcatg cattgcaacc accttctgat agttcgcttt ttctgatcaa
     1801 ttgaacttct ttcattttct gttcctcctc ttagttttct acttatgtat tttttatcac
     1861 ctgacgtaag tgtattttat cgtcacgatc acgtgattta ttcttcagag attctacctg
     1921 aataattcat acttttaatt aaaaccatgt gaaactgcct cacggcagct tacaattact
     1981 ttttcatctt cacccgttaa gtgatgaaaa aagaacccct ttctgctatg gttaaagtga
     2041 ctaaaccaac caaaagaaag gagttctttt catgactagc ttacacaaaa accaagtaaa
     2101 attcaattca aatatcacta tttctcatac aggtggtcaa ttatcgagtg attcgggtct
     2161 cgtcctagtg aaagagctga tgaacatctt tggtttttct gaactggcta agcaacacat
     2221 tcacattgaa gacgaacgag cgtattttac tcatgacaac ttatccatac ttgagcagtt
     2281 cattatgcaa ttaattgctg gttactcagc tgattctgca gctaatctcc tgagacaaga
     2341 tcctgtgttt aaagctgttt tagataggaa agaactcgct tctcaatctt cactttcccg
     2401 atttttagat cgactatctg aggagaatat ccatgaactt caagctttga accaagaact
     2461 tatcgataaa gcacgcctca tccgtaatga tacggaatta atcattgatt tagattcgac
     2521 ccattcagat acatttggtc accaagaaca aacgaattat aatacacact accaaaccta
     2581 tggttaccat ccattggtag cttttgacgg attgactggt gacttcttaa aagctgaact
     2641 acgttcagga aatcaatata catcaaaagg cgtaaaggag tttctcacac ctttattaga
     2701 gcactataat cactctctac caaacactga catcttggtt cgtggagaca gcgggttcgc
     2761 tacacctggt gtgtatgatt cgtgtgaatc aaaaaagagt cattatgtta ttcgactgaa
     2821 gaataatcgt agactaggtc aaatagctga gaaatcagta ctttatggcg ataatcaaaa
     2881 gtgggaagaa cgagaagttc agtacttctc gaccacttat caagcacaat cctggtcaca
     2941 aagtcgtcgc gtgtgtatac gctcaacacg tgaagcgggc gaactactct ttcgacatga
     3001 atttatcgtg acgaatctat cagaaaatgt ttctcctgat accatctttt ctatctatgc
     3061 caaacgtggc acaatggaga acttcattaa agaagcgaaa gctggctttt actttgacaa
     3121 aacagacagt cctcgctttt tggagaatca tgtccgaatg atgctcagct tgatagctta
     3181 caacttagtc aacttcttaa gaacgattgg ctttgaagaa gtccaaaagg gaatgaccat
     3241 tcattctatt cgattgaagt ttctgaaagt tgctgggaaa ttagtccaaa cgggtagacg
     3301 agtctatctc aaattatcta gttatcatgt gtatcagaat gaattctaca gggtctttgc
     3361 tcgcctgagg cgagccagtc aatggatcta atccaacaat ctaacgattt ttttactggg
     3421 aagttatcca gggagaagta tgctcaaaat gccttacacc caaaatttat tcctcaatat
     3481 ttttgaacag tgaatgtttg aagtaacttt ttagtcaaaa tcagttgata gggatattag
     3541 tgatacatat ttcaataaaa tgtgccaaag aattaaagct atgaattatt caggattcta
     3601 tttatctatc taacatatcc tttattcttc tacttttctt tctttagcat ataagagata
     3661 cgcatagtaa tcaagcaagg attgttgata taaaaagaac aaataccgct attttgattt
     3721 cttttgactc tattactcat ataaataaaa tttattatac ctgctctttt tgactatatc
     3781 ctcatctgac tcctatactt cgtttgtatt aaaacttagg aggaatcatt catgcttaca
     3841 gggctaaact tattaaataa tccttttcta aataaaggaa cagcttttac aaaagaagaa
     3901 cgggcaaaat acggaatcac tggtatgctt ccaagtactg tccaaacatt ggaacaacaa
     3961 tctgtccaag cttacggtca atacttaagc aaacagaccg atttggaaaa acgtatcttc
     4021 ttaatgaatc tattcaatac gaaccggaca ttgttttata aattgatggg cgaacattta
     4081 gttgaattca tgcctgtcgt ttatgatcct gtcgttgcgg attcaatcga acaatacaac
     4141 gaaattttct tgaaaccaca agatgctgta tttctttcaa tcgacgaacc agaaaatatc
     4201 aaagcaagtt tgaaaaacgc agcagatgga cgcgacattc gtttgatcgt tgtgacagat
     4261 gcagaaggaa tcttaggtat gggtgactgg ggtgtgaacg gtgttgacat cgctatcggt
     4321 aaattgatgg tctacactgc cgcggctggt atcaatcctg cacaagtctt gcctgtatca
     4381 atcgacgctg gtactaataa cgaagaatta ttgaataatc cattatactt agggaatcgt
     4441 catgctcgtg tagaaggcga aacttactac gaattcattg atcaattcgt tcaatcagct
     4501 actgaattat tcccagaatt gttattacat tgggaagatt ttggacgagg aaatgctgca
     4561 acgatcttag aaaaatacga agataaaatc actactttca atgatgatat ccaaggcaca
     4621 ggaatcgttg tactagctgg tgtattaggt ggattgaata tatcaggtga gcaattgaaa
     4681 gatcaaacga tcttgacatt tggtgctggt actgctggtg taggtatcgc aaacatcctt
     4741 ttagatgaaa tgatccgtca aggtgtacct gaagaagaag cacgccaaca tttctatcaa
     4801 gtagataaac agggtttatt gtttgaagat acaaaaggat tgactcctgg tcaaatccca
     4861 ttcgctcgta aacgctcaga attcactaat gctgatgaat tgacaaactt agaagcagtt
     4921 gtaaaagcaa tccatccaac gatcatgatc ggtacttcta cccaacctgg agcattcact
     4981 gaagaaatcg tgaaagaaat ggcggctcat accccacgtc caatcatcat gcctttgtct
     5041 aatccaacaa aattggcaga agcaaaagca aaagatttga ttgaatggac ggacggaaaa
     5101 gctttagttg gaacaggtat ccctgctgct gatgtggaat ataacggtgt aacttaccaa
     5161 atcggtcaag caaataatgc gttgatgtac ccaggtttag ggcttggttt gattgcttca
     5221 acagctacac gagtaaatgc tgaaatcatt tctcaagcta gtcgagcatt aggcggaatc
     5281 gttgatgtaa caaaaccagg agcagctatc ttgcctccag tagcaaaaat cactgaattc
     5341 tctcaaacga ttgctgaaac tgtcgcaaaa tcagttgttg cacaaaaatt gaatcgtgaa
     5401 gaaatcacgg atatcaaaga agctgttgaa tctgctaaat gggttcctga atataaatct
     5461 ttagaagatt aagattgtta tagtaaaaga acatacagaa actttgtatg acgtctaaaa
     5521 agaaaaaagc gactgcggca aaacagcagc cagccaacta ctgctctttt gccgcttctc
     5581 tttggctttt ttcatacgat acagaataag aaaggatctg taaaaatggc acaaaaaaca
     5641 acaaccgcaa ctgcagttga ggaaaagaaa aaagaagggt tttggtcaac aaaaattacc
     5701 ggcgtaagtt tgccccttta tttgatcatg gtccttgtcc tgatcattgc aatggcttta
     5761 ggaaaattac cgacgaatat gattggccca atcgctgttt tggtcatttt cggtaattta
     5821 tttcatttta tcggaacaaa aatccctata gtcaaaagtt atttaggtgg tggctccgtt
     5881 tttgcgatct ttgcctctgc cgcgattgct acatttggga tcttacctga gtatgtagta
     5941 aaatccacag aaaactttgt cagcaatatg ggctttttag acttttatat tgctgccttg
     6001 attactggta gcatccttgg tatgaaccgt aatctattga tgaaagcttc tgttcgtttt
     6061 attcccgttg cacttatttc aatggtcgtc tccttttttg ccgtaggact cgtaggtatg
     6121 cttatcggaa atggttttgc aaattccgtt ttatatatct cattgcccgc aatggctggt
     6181 ggtgttggag ccggagctgt acctttatca acgatttatg caaatgtttt aggtacggac
     6241 gcttcttcta tcatttcccg cctgattcct gcgacagcaa tgacaaatgt cctagctatc
     6301 attggtgcag cgttagttgc tcgtgcggga caatcaatgc caaaattcaa cggtaatggt
     6361 aaattaatgg aaaaaggcga ccttggcgat ggaaaaccta gaaatgtaaa accttccatt
     6421 ccacaattag gtgtcggttt gatggtatca ttgactttct tcatcttagg acaaatctgt
     6481 aactattttg ttcctaaagt ccatgcttac gcattcatga tcattatcgt tgttatctgt
     6541 aaaatcgcaa acctattacc agaatattac gaagatgcag ctatcatgtt caacaacttg
     6601 attgtcaaaa acttgacagc agctgttctt gccggtatcg gtattgcgtt attgaatcta
     6661 aatgtattgg cttctgcttt gacatggcaa tttgttgtct tatgtttgac aagtgttatc
     6721 gcgatttcag tagtttcagg atttgtcggt cgtttgtttg gtttatatcc aatcgaatca
     6781 actattactg ctggcttatg caacaactcg atgggtggta caggaaatgt agctgtctta
     6841 tctgcagcta atcggatgga acttattgct tttgctcaaa tgggcaatcg gcttggtggt
     6901 gccatcgttt tgatcatctc aggtttcttg atgcaattac tttcttagtc aaaaaaaata
     6961 cctgatcatc aagtatcggc ttgatgacca ggtatttttt gataaaaatt tacaggattt
     7021 tcaaaaatct tttttgcatt ttatcggaat gataaccgat gcgttcataa aatcggtgtg
     7081 cttctactct gtattctgca gaattaagtc ttattgctga tattcctcgt cttttcgctt
     7141 cttctacgcc agtcatcaag gcctttccga ttcctctttt ttcagcatgt ttagacacag
     7201 caagtgccat aatattgaac atcggatcgc tgaaaatcga ttcataggac tccgcttgta
     7261 catagccagc tgctttttta gaagtaggat cttcatagac caagaaaaaa tttttttctg
     7321 gctccttcaa cagtttcttc atttgtctca ccgtaacggt taatggtaca tcatatccta
     7381 attgttccgc attgatttct cgtagtgctt ctgcatctcc taaacgcatt tcccgcaaca
     7441 tccaaatcac cagccaattt ttattttttt aaatgaattt ttttatcaca gtatactcct
     7501 tttttcactt aaaaaaagac ttttcagtga ttttgacttg cttgaatcca gatccttcta
     7561 atgtttgcaa gatgacgaaa gcattgtaaa gattgatcaa aagaaccacg atgacaatcg
     7621 cttgaaaaat aaaggtcact ttttttggag acaaaaccct gctaaatctt gctccccaca
     7681 aacctccaat aacagcagcg gggataacat aaaacaacat agataaatca aagcgcataa
     7741 agctacttgt taaagcaatc gttaccaatt ttgccagttg agaaaagaaa atcgtagata
     7801 gagaatatag tgttgcttct tttattggca atgcaaacat cagcatcaac aaagaaacat
     7861 tgactggtcc accaccaata cctaaaaaac tagctaaaaa gcccagaacc cccccacata
     7921 taaggtacca agtccatgac gtcaaatgaa attttggctg atgatgcttg gtgtagaaga
     7981 acgcaaaaac caaggtcaat accgtcaaaa aaatttggat cagctgcaca tgcttctcgt
     8041 tttcaaataa ctgtaaaaaa acttcgaata caatgttgcc gactactcct ccaacaacag
     8101 ctccactaga tacccaaccg acaatctgcc aattcagtga tttcccgctt gatacttgtc
     8161 gcacagtcga aacaatggac atcgtgaata ccgcaactgt tgagtaaaaa gaaatccctg
     8221 caacagaatg ggcgccgata agatcaagaa tcggtttgat caacacgcct ccacccatcc
     8281 cggaaatagc gccaactgtg ttcgccagaa cgatcaccac aaaataaatc agaccaatca
     8341 tcttgtattt cctttctctt gtttatatct tttagcgatt gttactcttt tcttttatta
     8401 tacagtaaaa gaaacaaacg aggcttcgaa agcttttcta ctttttaagg aaatttagtg
     8461 ctaaacgaaa aaaccgggct ctacttttca gagagtccag cttttcttac accttatcga
     8521 ttcttttgtt ctattcttct tccgccatga atgtattgaa tacttcttcg atcatatccc
     8581 attctgcgtc tgtttcgatt tgttctaact cgccttctgt tccatcttcg ttttcgatgt
     8641 atgcataagc ttgtaattct acatcttcat cttctgaaac accagctgga tataaaagaa
     8701 catagttacg tccaaattct tcttgtccgt caactgttag caagatttcg tataatgttt
     8761 catttccttg gtcatccacc aatgtgatgt gttcgtgtcc ttcgtgttcg tgggaatggt
     8821 tatgttctgt cataagatta cctcttttct ttttattatt aaaataattg cttacctgag
     8881 ccgtctaaat aattttgtaa aatcatcaca gctgctaatt tatcgatgac tttttttcgt
     8941 ttcgctcttg aagtatttgc ctgctctact agcatacgtt ctgcctgaac agtggttagt
     9001 cgttcatctt gataatcaac cggcaaggag aatagttctt tgatcttctc tccatatgac
     9061 atggaagctt ctgcccttgg tccgatggaa ttgttcatat tcttaggtaa tccaactaca
     9121 aaacggtcta cttcgtactg cgccactaat tccttcaacc gatcaaaacc aaactcttct
     9181 tctgcctcat tgattcgaat gatttctact ccttgagctg tccagccaaa gggatcgctc
     9241 acagcaacgc ctactgtctt agaaccgaca tccaagccca ttactctcat aaattcactc
     9301 catgatttga gaggtagtct ttgacaatta cttccatgat ttcatcgcgt tcgtgacggc
     9361 gaatcaaatt tcgtgcatca cgataacgag gaatgtaggc cgggtctcca gaaagcaagt
     9421 agccgacaat ctgattgatt ggattgtagc ctttttcttc caaagcccga taaacaatcg
     9481 ctaatgtttc gctcacttct tttttgcgac tatcgtcaaa accaaaacgt acggtttcat
     9541 ctgtaaaacc catgattcta cacctctttc ccgcaaggta attccagctt accttctaca
     9601 cccttatttt actcgaagaa agggaaaact acaaacaaat attccaaact tctgaataaa
     9661 ttaagaaaca cgatttgtct gatttttcct tttttctgtg gctttttcaa aagccctctt
     9721 tccataaagt atacgctata tttctttgaa agtatgtttt tacacaattt tttcataaag
     9781 ttcataaaaa attcgaattg ctgctactaa tttttcgttt tcgttgcttg ccctgtctca
     9841 taattgatgg tgtagccatc ttgaacattg tagataaaga cattgaattc aatttttttg
     9901 tcttcaatgc tttctgcttc caactgcaca cctcttgcta ccagttcatt tccctcgaaa
     9961 tgaggagtga cacgatagcg tacatgatga tttgtttcct tgatatatgc cgcaatatca
    10021 ttttcgtggg caagcatgta cggagcattc aacgaacgtg tccctgtcat taagttttta
    10081 atgttattat tttgaccagt caactggaaa ccaatcaaat ggctgcggtt gtataaccat
    10141 tgtccgtcac ttaatttctt ttgtttccaa cctgtcggat caatatacaa aggttctctc
    10201 ttttcagtag gaaacaagtc ttttcccaac atcgcattgg cttgtcctac tctgttcaat
    10261 ttgtctatat ttgaatagct ttcccatgtc cctttggaaa gactaagatc ctcttttgta
    10321 aactccggct gattcccatt gatttctatt tcttgatgtt ttccatcata ttctggcaca
    10381 tccgctactt gagaagcttg cggtgtggaa tcaaaaatgg ttgtaatttg ttggaagata
    10441 tctgaatctt tttgtgtggt ggaaataccg agtgcccctg caatcacagc agcgacgatc
    10501 cccacgatcg ccttggttgt ttttttgctc atttctttac tcctttacta acagttccct
    10561 aaatcttaac atatgttccc ctataaataa atactggaaa gaaatagaaa cagtaaaaaa
    10621 ataaaaccag tttttagacg gcttaagaat acaaaaaaag agacggattc atcgtctcta
    10681 ctcaatcaca aaacactatt tacaaggtat ttattatcat tcaaaaaatt tttcttaata
    10741 ctcaaaacta aacggcttct gtacgacctc ttggtaaaca gtgttcaaaa gcttgcatct
    10801 gcggtaataa gtccaaccaa gtcaaaaaca taagaagctt ttttgcttga ctattcttat
    10861 tacttgatgc agggcagctt tttcacagcc tcttttaagc gggtgacggg aatcgaaccc
    10921 gcgacatcag cttgggaagc tgggatttta ccactaaact acacccgcga tacaaaaaca
    10981 gtatacgcct ctttcactcc ttcctcaagt ttttttattc tttacgcttc cgatatgttt
    11041 tgtagtaaaa taaaactaat caatcaatta ttggagaaga tgctatgacg ggaaaagaat
    11101 tagatctgtt gctggacact tgtttactcg ctgggaaaat catgatggaa agcaatgcgg
    11161 agatgtatcg ggtagaagat acgatgagtc gaattgcttt agcttctgga aatttccgtt
    11221 tggtcagcta tgtcactcaa accggtctct ttattggtct tgatcgtacc tcgaccatcc
    11281 gaatggaaca aattaccaac cgttcgatta atttagaaaa agtagtaaaa gtaaatgatc
    11341 tttcacgtaa atatgttgct tcagagctaa cattagaaga actttactgc gaactgcaag
    11401 caatcgaccg agaccgttct ttctttcctg tctggttgca aatcgttagc gcggcagtga
    11461 tcagtggaac aattatggtg ttatttggcg gaaagatgac cgatttacct gtgactttag
    11521 tcattggagg attgggatac gcagcttatc tatatagttt gaaatttttt agaatcaaat
    11581 ttttatcgga atttttatct tctttattga ttggcatagc cgctatctac agcgtacgtt
    11641 ttggcttagg aagcaatcag gatctaatca ttatcggatg tgtgatgcct ttagttcctg
    11701 gagttcaaat tacgaacgct atccgtgatt tgctagctgg acattatgtc tcaggagttt
    11761 ctcgcggaac agaagcgatg atgactgcta cgatgatcgg ttttgcgatt gcttttattt
    11821 tccagctttt ttattaggaa aggaacacaa gtatggggac gatatttatt cagttttctt
    11881 ttagtttttt agcgactgcg gcatttgccg ttattacaaa tgtacctagg cgttcattga
    11941 tttgttgtgg tctttctggt gcttttggct ggatgatcta ctggatctgt gttcaaatag
    12001 gcggatctgc tgcttttggt tcattgcttg gttctttagg agtagcattc atcagcgatc
    12061 ttttctctaa acgtttgaaa atgcccgtaa cgattttcaa tattcccggg atggttcctc
    12121 tagtccctgg tggtttagct tatcaagcgg ttcgaaatct cgttactgaa tcctatcgag
    12181 aagcggctca ttatgcggtc caagcaatta tgattgctgg agcaatcgct ttaggtcttg
    12241 tattatcaga agtctttaac cataacatcc gtaatttcaa agtaaagcgt gacgcaatca
    12301 tgatgaaacg aaaaaaacgg ctttttaaat aaacgaagtg taacaaagaa aaggttgtga
    12361 aagagacgtt cagccttgag cgatgacaaa atatctcaca aacattgcga caagtaaccg
    12421 caggagcaat aagaagtaat tatgagtatt aaaaaaagtt ttgtaaaaat agcttctcac
    12481 atttttacat aaaattgact taatactgag aaactgactt ttgaacaccc tctatctgta
    12541 aaaaaggggc tgcgacatga tttttgtcac ggcccctctt ctttattcaa attttttcca
    12601 aaacgttcgt tgataataaa cgatccatag agcggaaagt attagaacta aaccgatcac
    12661 aggaatattc actaaccaaa atggataaaa caaagccaac attccgtata agacgataag
    12721 aataatactg atgatcaatg aacccatcat agttgcgact aaacccaaac ttcctgaacc
    12781 tctgttaaat aattggttaa tattggtcca gttcagcagc agcaaccgat aatctctagc
    12841 gaaataacgt agtgacaata agtagcagcc gaataaagaa ccaaatagca agctagggat
    12901 aaaaaacaaa ggcagctgaa aagacagtcc gcttaataat gcgatcccac cagttaaaaa
    12961 actctgcaat atccatccga atctgaactt ttcttttaaa tattggttca tagagattgg
    13021 caaagaacgg ataaacagaa aattttcttg atccaaagaa ataagattgc tgataaaaga
    13081 agtctgatta actgttaaga aagccaatgc gatccctacc aggaaaacaa caccgattaa
    13141 cttattatct aaatcagtta attttatttc gcctcctagg gcaaaagcaa gaataaaaat
    13201 gattggagtt aacaaggaag aagaaagaac ttgcataatc aaattaggtt cttttactaa
    13261 ttgagcattg taactaaata aaagctgatg cacattttgg ttctttttat gggttctttt
    13321 tattttgaac tcactgtttg aatcagtcag ttgctctgta agctttggta ctatcagctg
    13381 ttttacagca aggaaaaatc ccagagccgt gatagctagt attccccaac ccaataaacc
    13441 ttgttgagaa agtggctgac tggcagcatc atagaatggc aataatatcg aaatcggatg
    13501 ccgatctgtt aactcatttt caatagtccc cgtttgatga ttcatccaca tgattccagc
    13561 aaatgcgatc agcatcgagc tgccaagcaa gatactagaa actgtttttc tatgtttttt
    13621 aaacactgct gttcgagcca aaccaaaaac aatcaaacta gccagacaaa aaagaataat
    13681 caaaaataga gaaaacaaaa ggattgagat aatgatagta agcaaaatcc ctagatcagc
    13741 tcgccatccg gttaaaataa acatgactag aagcggaaaa acaaaaggaa tgatggtcaa
    13801 agcaactacc aaaatctttg ctgaaaaaac ctgttcttgt ccaaaaggca gaggcaaaaa
    13861 tacttgcagg tcatttcctt caaaaaagat attataaatg actgatatac tttgagttaa
    13921 acctaacata ccaaaaagtg ccacgtaata agtaaagaaa cctggcaatt taacaaagtt
    13981 catagcaaac atagcaaatc cgtaaatcag taaaaaaatc agccctgaaa aaagattttg
    14041 agacaaaaga tagatagtta atcgctttcc cttttttcct ttctctcttg ctttattcgt
    14101 gagctgtgga ttaacatata aaagattaac tcgaattaat tctaataatt gtcgcttata
    14161 catacggtcc atctcctgtc gcttgccttc cagccatttt caaataaatc ttttctagcg
    14221 tttcatcagg tgagccattc aataattcac taactgcccc ctgataaatc aattcacctt
    14281 tcttcaaaat agccagttta tcgcataact gttgtgcggt atccaataca tgtgtagaaa
    14341 aaatgactgt ttttcctttt gcggcatgag ccttcatcat ttctttcaaa tcaaatgctg
    14401 cttgaggatc aagtccttgc aaaggttcat ccaataccca aatatctgga tctggcagca
    14461 acgtgccgat caaaatcgtt ttttgacgca ttccatgtga aaaacttgcg attgtttcat
    14521 tttgatgact atacatatca aaaagcgctg tcaattctgc taaacgcttt tctttttttt
    14581 gtgtgtctaa ttcataggca gctgaaatca agtcccaata ttctccagcc gtcaattgta
    14641 aaaaaatatc tggggaatca ggcacataac cgattttttg tttgatactc aatcgatttt
    14701 ccgtcaattt cattccatct actaaaatcg ttcccgatga tggttcaata atactaacta
    14761 aacttttaat cgtagttgat tttccggcac cattatgtcc taaaaatcca aaaatttccc
    14821 cttgtcttat cgagagagac aagtctttta atgcttgttt tttcccgtaa cttttactta
    14881 cattgatgaa ttcaatcatt tctgtactcc ttttgtttgt tattactttt tattgtaccc
    14941 ttcgttattg gtggagtaaa tgtcaaaaag agtgcataac aaaaaaggat agaaacgact
    15001 aggctgctac ttgggttgtt ctcttctaca ggaaaacact cttctaacag gtaagatatg
    15061 agtctttgtt ttctttaaaa tgattcattt tctatctttt cttgcataaa attctttagt
    15121 ttatcaatac ttctctttcc catctctagt tgttctccat ttgcaaatgt tactatttcg
    15181 tttactctgc taatagatgt aatgttttca gtattaatga tataagcttt taaatcttta
    15241 cataaatact catattcgag tgatttttta tattttttaa ttgtgccgtt tacgagaatc
    15301 tcttcatctt tcaatactag gcctatttta tttttataac ctggcatgct cattagataa
    15361 aggatttcat cgtaatggat atagtgatcg ctattaccat aacggacagt tgtccacctt
    15421 tttttcgtag catgttgaac aggatagttt tctttttctt tcaataagta actttggatg
    15481 ctttttttat ttttttcata agtgaattct tttatcaaat aaccactagg cgtaatcttt
    15541 cgattaataa cagttattgc tttattcgga tgagacgtta gataaacaat tttacacttt
    15601 tcattctttt ctctaagcat ttcgcctagt tcgataccgc tataataggc gttcaaatcg
    15661 atgtctagga aaaaaatatc tgaggaatag atttcattat ttttaatgaa ttcaacaaat
    15721 tgtataacgt tcaatccctg aacgatctca aatttccaag gacttaataa aattctggat
    15781 tcttccaaaa tttctactag cattttttca aaaaccaaac tatcatccaa aataaatata
    15841 cgcgttacca taaaaagtac ctccactcga tattttacta tcaaaatcat ttcatacaac
    15901 ttttcaacat acatgttagg aataaattgt aattctcttc acaatctttt ccaacacctt
    15961 tgaaaccgat atcaaatact ttcaggatgc tgcttctaaa ataaatatca aacaaatgaa
    16021 tacatcatgc aaaaaaagcc agacaaccga cgtccttgcg tgtcagctgt ctgagctatg
    16081 tttatttatt ttgttctttt aaaaagaacg atacacatac tgatttttcg gagcagagac
    16141 tttctcagcg tttgtaacaa ctacagatgg gatttcacgc ttgaatggtt gataatagtc
    16201 tgattggatg gttccttcta ttttatacca ttcatcattt ttaaccgtta ctccttccgg
    16261 catatgcgtc aacaaaccaa agactcctga atctgccaca caatggataa tgccgaatcg
    16321 gaacaagaag atatctgtat tgctatcgtt cggtgtttgg taaacaaatc cttcatagct
    16381 gatttttttg ccaatgaatt cgctagggta attataaatt agctccataa cttctaaata
    16441 gttttcatct gtgatcttga tagtttgctt atccccatac ttttctttca actcattcat
    16501 ttggtctaag tagtctgatt tgttgaaata aatactggta tccggcttta agtattgtgt
    16561 ctgcatctcc ggatccccta ctgattcttt acttactggg aaattaaatc ctttggcttc
    16621 tacgatcgta gtgtcgagac taactgttgg aaacaacgtc cccacgatta ctggcaaagc
    16681 tagcagtaca taagcgattc cacgttgata aggttttgac aacccatggt catgatcgtg
    16741 ctcgtgtgcc ttttcttctg cttttccgtt tttgacccac aaatacagct gaactaaagc
    16801 caaaagagca gataaaatca ttgaaagaat agctaagtag cgataatgga cattgatata
    16861 ttgatcgagt ttgccagaaa cttgcaagta catcatcaat tcgaaatacc cagataaaat
    16921 caaaaaccgc agcatatttt ccctcctaaa taaataatgt gaatccaata acgctaaggg
    16981 caatcagtcc gatcagcgat aaaataaagc gtcctgtaaa atatcgtttc atcatcagta
    17041 gatttttgat atcgaccatt gggccaaaga ccaaaaaggc agctacaggt gctgtgccga
    17101 acagacttaa caaagaagat cctataaacg catctgcttc tgagcaaaga gacatcgtaa
    17161 aggccaataa cagcatgatg ataatggcta aaatctttgt tgagccgagc gttagcataa
    17221 ttctagttgg taaataagtc tgcatcgcag ctgcgattaa tccgccaatg atcaaataac
    17281 gacctgtatc aaaaaattcg tcgattgaat gtgtcaacac atgcccagtt tgatggatca
    17341 gctgattttt tggttcattc ttctcacttt gttcttcttc atggacatga tgatggtgat
    17401 tttctgctac tttagacgtg attttttctt tcaatacagc gtctttttga aaataggcaa
    17461 gccagacacc aatcacaagg gcaacaaaaa agctgcctat cacccgccag cttgccatct
    17521 gccaagaatt gccaaatgcg ataaaagtgg aaaaaatcac gattggattg atgatcggag
    17581 cagtcagcat aaaagcaaac gctgtgtgaa ctggtacgcc ttttttaaca aattgatgaa
    17641 cgatcggtac gatgccgcat tcacatgaag gaaagaaaaa tcctaagatc gaaccagtaa
    17701 aaatagagaa gatacgattt tcaggaagcc atctcttcac acgttctggg gtcaaaaata
    17761 cttgtaaggc gcctgagata agacagccta ataatacgaa aggtaatgct tcaataacga
    17821 tcgataagaa aatcgtactc atctgcaaaa ccgaatttgg aataaaagaa aacatgagtt
    17881 tcctcctttt tatttctagt tcattcgctt tgcaaatata cgcttttatt caaaaaaaac
    17941 aagttgctct gtaaattttt acacaactct tattttttac caaagcactt caattgactt
    18001 tttctgttat tcccattaaa ttaaggtctc atacatatca cttctatcat aaaagggaga
    18061 ataaaaatga aacaaaccac taacttgact gaagttcaag acatactgca acagtcatcc
    18121 gttgccgtca tttatctttc gatgcctaat tgcagtgttt gtcacgctgt tcgtccacga
    18181 ctagaggaac ttctcacaca ttatgatatt ccggcacttc atttggatgc atttgaaaca
    18241 ccagaagtag ctagtaaatt tgaagtgctg actgcgccag ttgtcctgat ttttcatcaa
    18301 ggaaaagaag tctttcggca agcacggttc atcgacttta aaaaaatccg ttatctacta
    18361 gatgaactga cagcagaaga tgattccctt tcttatgaag aaatcttccg aacaaaataa
    18421 tcgttgtcca aacagaaaaa agcgattgaa caagtgaaag ttttgccttc atttgttcaa
    18481 tcgcttttta tttttattct gctgtatttt cggaatgcgc atttgcgtca gaatgcaaga
    18541 aatagatcaa ggtttgcaat tcattcgtca aatcaacatt ttggatcaat acatctgacg
    18601 gagcattcaa tcgagcagcg gtaaagttca agattccttt gattcctgct tccgttaact
    18661 gattgactac ttcttgtgct ctttcagcgg gtatcgttaa aattgctact tcgatttgtt
    18721 ggatcttgat ttgttctgac atatcttcca ttggataaac ggggataccg tctacgatgc
    18781 gcccaacgat ttcctcattc acatcaaaag cacaactgat acgtatgcta ttactttgat
    18841 ggaatttgta ttttagtaaa gcacttccca agttccctac accgatcagc gcaacatttg
    18901 tcaattgatc gtcgtttaat gtctttgcaa aaaagtgcat aagatcttct acatcataac
    18961 catacccacg ttttcctaat tcgccaaaat aagaaaaatc tcgacggatc gttgcactat
    19021 ctacttgaac ggcttcactt aattcagttg aagacacttt tttctttcca gcattattta
    19081 aaatccttaa atagcgataa tacaaaggca gtcttttagc tgtcgccttt ggaataatat
    19141 gatctttcac gaaatgacct ccacgtattg tctaattaca tctttgattt ctccatcata
    19201 gcagtattta taggaaaaaa tcaattccat tgctcagata ttgtgaaatt ttattcttta
    19261 ttcatttatt tatcatttct gcaaatctcg cagtataatg gaatttatgg tagactacta
    19321 attgaaaaat agttttttat ttgaggagaa ttcacaaagt agaaaagagg attccatgat
    19381 attattacaa gccaatcaga ttgctcgcca ttttggtgca gaagtcttat ttgaaaacat
    19441 acatttagaa atcagtacag gcgctcgtgt cgctttagtt ggcagaaatg gcgctggaaa
    19501 atcgacttta ttaaagatca ttgctggaat tgaagcacct gatgaaggaa agatcgctaa
    19561 aaataaaaca gcgactctcg gatacctcgc tcaggacaca ggacttgatt ccaatgaaac
    19621 agtttggaac gagatgctga aagcttttga acaagttaga caaatggaag agcggatgcg
    19681 cgagctagag attttcatta gcgaaggtac gccagacaca cctgcttata gttcttattt
    19741 aaaagaatac gaccggctgc aacacgattt ttcagatcga aacggctatg gttatgaaaa
    19801 tgaaattcgt tccgtattgc atgggtttaa attcgattct tcattttatg atcagaaaat
    19861 cgatacttta tcaggcggac agcgcacacg tttagcttta gctcgcatgc ttttgcaaca
    19921 ccctgacatt ttgattctag acgaaccaac gaaccattta gatatcgaga cactttcctg
    19981 gcttgagaat tatctgcaaa gctatactgg tgcattattg attgtttccc atgaccgtta
    20041 ttttttagat aaagtagtca atgaagtcta tgaattaagc agaagaaaaa tgcgccatta
    20101 caaaggtaac tattcgaaat atctagattt gaaagcagaa cagttagcaa gtgaatggaa
    20161 ggcttatgaa aagcagcaaa cagaaatcca taaattagaa gacttcgttg ctcggaacct
    20221 tgttcgcgcc tctaccacaa aacgagcgca aagccgcaga aagacattag aaaaaatgga
    20281 ccggctggat cgtcctcaag gggatgaaaa acaagcaaac tttctattca gtatagaaaa
    20341 gccttctgga aatgtagtct tgcaaatcga agatgccgct atcggatatg ataatgtcac
    20401 cttatctgaa ccaatcaatc tagatatccg tcgtcaagaa gcgattgctc tagtaggtcc
    20461 gaatggtatc gggaaatcga cgttgctgaa atcaatcatt caccagatcc cttttatccg
    20521 tggaaaagaa acgctaggga caaatgtcac catcggctat tacgatcaag gtcaagctga
    20581 tctgcataca aacaagacga tcctagcaga attgtgggat gagcatccta ccactccaga
    20641 aaaagagatc cgaagtgctt taggtgcttt cttattttct ggcgaagatg tagaaaaacc
    20701 aatccctctg ctaagtggcg gtgaaaaagc acgggttgct ttagccaagt tagcgatgaa
    20761 caaagaaaat tttttgattt tggatgaacc aacaaaccat ttagatattg acaacaaaga
    20821 agtattagaa aatgcattga tcgattatga cggcacactg ctttttgttt cccatgaccg
    20881 atatttcatc aatcggatcg cgacaaaagt cgtcgaactc tctgaaaatg gcagcaaagt
    20941 ctatctagga gactatgatt attatttaga gaaaaagcag gaagaagaag aaatcgccga
    21001 attgttggca caagatgagc cagaatctgc tcctgctccc acgaacaaat ctgattatta
    21061 ccaaagcaaa gaacagcaaa agcttatccg tagccttcaa cgaaaaatta ctcaggttga
    21121 agaagaaatg gcgcggatcg atgaatggat cgatcagttg gaacaagaaa tggtcgcgcc
    21181 agaaaacctg gaagatcacg taaaactcaa tgagctgaac caagatttag aagctgctag
    21241 acaagatcaa gaaacaaaat tgacggaatg ggaagaacta agcttggaat tagaagaata
    21301 tgaaaattaa cgaaaaaacc aaaacagaaa ccattcatgc tgttttggtt tttctttttt
    21361 tattttatca aacaaaaatt ccatatttac ctttttcacc aataagaaga ccaattacta
    21421 gtcattctca ctaaagcttc taaataatag taatcacccc aaatacaagg tgtatttacc
    21481 ccattatttt tgggcttatt ataaacagac tgtgttaaaa agccatcttc ttcttccgtt
    21541 gtagcatatc tttctttcaa ttgtcgcata attttccaaa cagcagactg gtataagttc
    21601 ttttctgttt tgtctaatag acctgattct attaattcta ataatccaca aaccatgatc
    21661 accatactag atgtatcttt ttcttctctg ctagaatcat caaagatcaa atcccaataa
    21721 caaatggtat cttctggcaa ccgattcata aaataattgg ctaatatttt gcttaaatca
    21781 aaatattttt gttctttcaa ataacgataa cttaatgcaa aaccgtaaat cccccatgct
    21841 tggcctctag cccaacagga attatcacta taaccttgat gcgtacttcc atatcttggt
    21901 tttccatctt tgacatccat ataaaatgta tgataagttg aaccatcttc tcttactaaa
    21961 taatctgctg cattttgaat atgagcctga gcagcttttt tatatttttg atttccagtt
    22021 tcttcactcg cccaatacaa taatggaaga ttcatgcaac aatccatgat cattctacct
    22081 tgttgtgaag gatcactagg atctccccaa gcttgtataa ctcctgcctt ctcccaaaaa
    22141 cgctgaagta atgtttctgc agcatcaatt gaagcttcct tcatttttcg atttcccgtt
    22201 attttataat ctgctacggt tgataaagaa tacaaaaaac caagatcgtg atgattagtg
    22261 ataatttgac agtcaatcct gtggataaaa tctatatctg ctttttcagc tgtttgttga
    22321 aataaaggat cacccgtctt ctcaaataac aaccaattaa ttcctgtcca aaatccttct
    22381 gtccaaccaa tattgtctct taatggataa cgtcctttta taggacactc gcttgggaat
    22441 tgatactgac tgttactgat acgtttgatt aacctctccg tgtgtctgcg acaacgctcg
    22501 atctcattat tccattcttt ttccattaat tctttataac attcatttat ccatttttct
    22561 ggatgtatta tctcttcaaa catcacttta tcaagcattt ccccaccagc ctttagcata
    22621 attttagtct ttttttattg tttttatttt ggatagttag cccggttgtc ccatcaaaat
    22681 caattttggg acgattgttc catacttcta aactataatc ccgatcttga tgagcaacca
    22741 ctcctgttcc gagccaatgg gttccttttc caaatgtacc ctctaatcca ggaataaaag
    22801 tgttttccca tgtcatcaag tttgtattgg gcaaacccat aatagctgtg gattttcgtt
    22861 taatagtatc gtcacttaaa cagataatac ctgaaaagcc agcttcactc accctatagt
    22921 tttccttgtc ttcttctatg attattcctt ctttctcagg agaacattca atagcaaacc
    22981 ctgtctcata tagaacatat tctgtatcta attctacttt gtgtacgcga atctgccagc
    23041 cttcaaaagg aataagccaa gttctgattt ttgcctgtaa agtaggttcc catgtagagg
    23101 caagtacctc tttcttacat acaatgtctc gtacattatt tcgaacgatg aactgtccat
    23161 aggttttgat gctctcattc ttaaaactgg tcgtgatata tgtgtccgct cgctgaatcc
    23221 ctagcattga atccattgcc atttctgctt tcaattgatt cgctcgcggt atcgaaaaac
    23281 caaattgact agaataagca aattttaaat atttttcatt ggtcaatgta tggaaatttg
    23341 gccctaattg tcccgcattc aaaaaaaatg tatgtccatt atcatgttgt atgagcaaat
    23401 tggcttctga aagaagttta gttccttcac gaataggcat aggcatttct ttagccgtcc
    23461 aatactcatg gtcttcaggt agcgccaaca ataaaaaaat cttattcagc cataatggag
    23521 ataacgtact attatagggt tcagtcaatg tcaattgagg gtaggtataa ccaatattca
    23581 ggataccttt ttcatcaaat atttcttttt gcatccacca tcttatattc cgattgacta
    23641 accccttgat ttcacctaat ttaaaaggca aaagatcggc ccacaacata gctgaccaaa
    23701 agcttgaaac tgcaaaacga taaatcatgc ttcgaccaaa aggcacattt gcaccatctt
    23761 ccgcaaaaaa atgaatatag tctctagaaa aatcaatagc tcggttctta tatatctggc
    23821 taatgggctt ttctggttct agtacgctat aaatcaaacc ataataatga aatgcaaaag
    23881 gattataata atcttggcga cctcttgaac tgtctcgata ccagccattt tgaagataac
    23941 aattttctat attatcaaat gcttctttca gtgctgattc tttaactgga taaccaaatt
    24001 tttggataat tgttccgaca attatcttaa aaaattgcca attaccatct gcacattcat
    24061 attcaaaaat ttgcgagaac caatgaataa tctggctttt ttctcctgta tctaattttt
    24121 tccataataa ttgttcatga tgatataacg ctaataacat tgcgggcatt tctaccatac
    24181 gctggtctct ttcatgtatt tctccccaat aatcgggatg ggaaggatct gttccagctt
    24241 ttattcctga tagaattaat ttcaaccatc gttcatctaa ttggtcaatt gcgggccccg
    24301 ctccccataa aacccgagag aatccttcca ttcctgcaat tttatttcca tatcctaccc
    24361 cttgatgtat ataatcaatt tgtgcgccac ttgctcgata aaacggctgg agtggttgat
    24421 ttatcttttt aaataagtca aagtaatcct gtctggtcct taatagtggt actggatgtt
    24481 tcattgtatt ttctcctctt tttactacca aatagctaat tccgactgtt ctaatcgaag
    24541 taagccttca ataaaaaaat aatcagaata gatcagtggc acattataag tcagttctct
    24601 atggtatgct tctgctccgc ctccaatgat cccatcttca tccatattcc aatttgcata
    24661 gtgcttttct gtcttttgga gtatattgat agcagcttca tgatacattt ttgatcgtac
    24721 agaggaaaca tatcctgcta attccagaag accgcatgca gcgcatactc cagcactggt
    24781 atcaatattc gaatctttta cagcaaaatc aatgagagga atataaccag ttttttcgat
    24841 tttctgaata aaatttactg ctatcttttc tgctatagct agatagtacg gattttttgt
    24901 gtaacgataa cttaacgcga atccatataa agcccatgca tttcctctgc tccaacaaga
    24961 attctcattg tatccttgcc cgccaagtaa ccgaatatat ttccctgatt ctgcatcaaa
    25021 ttctgcgata tgcccggttg atccatcttt cctcactaga tacttagctg ttgtatctgc
    25081 atgctgccga gcaattttag agaacctcgg atcaccagtt tccctcgaag cccaatacag
    25141 taatggtaaa ttcatcatac tatcaataat catccaacca ggtttatggt cattccatgc
    25201 tactaaatag ttccctgaaa tattatagcg tccagcaagt accgtagctg catgtaaccc
    25261 tagttgtcga ctatgtttgt tttgagactg ttgataatgt gcaatagccg atggtaagaa
    25321 taaaaaacct acatcatgat gaacgtctga aaaatggtac agggcagatt ctaataattg
    25381 ttcttgttgt attgctgcct ctttgaactt ttctcgtttt gtcttgtgaa agagctgcca
    25441 taaaatacca ctccaaaaac cattggtcca ccagtcgatt cctctgtcct ttattacgtc
    25501 tgtatatttt ccgttgtaag aaatatatgg aattttattc cccattctgt ctaattccgc
    25561 atctatcttt tcagaagcta cattcaaaat ttttcttgac cattccttcg tctgttcatt
    25621 catggatatc ccgccattct tttaattttt atgaatgtgg agttgctcct agaacgaact
    25681 agatggttaa cattcgttat tttttttact tatttgcagc tccaatgtca ttctccttaa
    25741 atttagactg cgcccacaca taaatcaaga ccattgggat cactgaagtt gctaaaatta
    25801 gcataattgc gccataatta attggctcac ctgtactaga aaccgtcata tttttgataa
    25861 ttaagggaac cgtatattta tctttatctg aaagcatgac taatggaaat agatattgat
    25921 tccaacttcc cataaagata agtaaaccac tagtaataat cgtaggtgat aaaatcggta
    25981 cagcgatttt cgtaaaaatc acccactcat tggcaccatc gattctggca gcctccatca
    26041 gtgctgtagg aaattgactg ctatattgtc gcatcataaa cactgaagtt gtactggcaa
    26101 tcgaagggat gatcacacct gcataagtat tcgataatcc taaacgactc ataatgtaaa
    26161 ataaaggaat caatgtggta aaaaaaggca ccatcctaga tagcataact gtattgaaca
    26221 acagtttatt ccccataaaa cgatactttg ctaatgcata acccgccatt gtagaactgg
    26281 ctgtagctga aactgtactg attacagcaa taacaatcga attccaaata atcaagggat
    26341 aattatatct cgccatgatg gcttgccagt tttttaatag catatcccca aacttgaaat
    26401 tgattccgcc acttaaaatt tcttgattac tttgcgttga agctacaatc atatataaat
    26461 atggcatcaa aaatattaag gcaccaaaca caataatgac gtacgtaaaa attctgcttt
    26521 gtatcttttg tttagtcatt tttatcacct ccgaatttaa attgaatagc cgataatata
    26581 acagatacaa acaccatcgt ccaggcaata gcagaggctt ttccaaaatc aaccatttca
    26641 aaacttgttt tatataaatt gactcctacg accaaagctg aattttctgg tccattggaa
    26701 gtcccaaaga atatatttgg gatattgaaa ttacccaagc cattgatagt ggctaaaact
    26761 gtggccatta aaatgattgg ctttagcatg gggatcgtta ataaaaagaa ttgccgaaat
    26821 ttcgatgctc catctatttc agcactttcg tatatctctt tagaaatccc ttgaagacca
    26881 gctaaaaata aaatagtgtt atatcctaca ctaagccaaa tcatcgtgat gatcattgat
    26941 attcgtatcc aaaaaggatt tgttaaccac tgtacaccgt taattcctag cgcattcaaa
    27001 aatccattga ataacccagt cggattgaaa aaagtcatga atacggaagc tacagccacc
    27061 gttgatgtaa tggttggaat ataatagaca gttctaaaaa atccttttcc ttttaactgt
    27121 gctgaattca ataaaacagc aaagtaaata gctaatagca tcgttattgg aattgatcct
    27181 gccatgataa tcaaaacatt cgtgtaagat ttaataaaca atggatctcg gaagatagct
    27241 agataattgt caaatccaac aaattcaaat gagtagccaa ttttcataaa actaaaagca
    27301 aacgagataa tgatgggaat caaaatcgtc acaataaaga aaataacaaa aggtgtgacc
    27361 aatccataag cacttttttt atgagacgta tctgttgctt ttttcttgct gttctttatt
    27421 gtcttgcttg gtaacgaaga ttgcatcatc gttaagtcct cctaatattt tttaatcacc
    27481 agttaatttt acgccgtact tatgagcaaa attttctgct tcttttagat atgaattttc
    27541 aaaatcacct gtttgccaat agttatatgc agcggtagtc aaataagacg tagcatctga
    27601 ataagtggct ggtaaaacag tatttgatgt attttcattg attttattca atagttcata
    27661 gtatttttgt cctccttagt agtcaaactt tttctcagct gcttctgttt gataggccaa
    27721 tgagttagat gtagccacgc ccagctccag tgcgttggct aagcattctt catctgtcag
    27781 cataaatgta agaaattgtt gtgccacttg tggatttttg gcatctttag ggacataaaa
    27841 acttgatcct cctgatactg caccttttcc tggattttct tttgaaaaag gaatcagtgg
    27901 agccatgcgc catttgtcag atgcatcagg aaaattcaaa gacatattcg tagcatacca
    27961 gccgccagca acaaacattg cagattcttg aaatgctttc tcagcatctt gtgcaccgta
    28021 gaaatgtaca atatctgagt cgatcatttc tttgattaac tttgcagcat gtttcgcttc
    28081 tttagtattc agacggatat ttccttcttc atcaagcaaa gattgattct gctgggctag
    28141 catgttgata aacaattctt ggtccccaga ttctggcaag gcaattccaa aactaccagt
    28201 tttttctttt aatgcttttg ccacctggat atattcttcc caagaactga tttcttcaaa
    28261 atctacacct atttcagcaa atttttttgg ttgataataa caaagtgctg gggtaaaatc
    28321 actagcccaa ggaataatcg tttcattact cgtttgttga cgcaaaatat tcaatttttg
    28381 atcataaaac tgatcgccat atttgtcata aaatccatat tcatcagcac tataaaaagc
    28441 atcttgaaat ttttccagca cacctgctgc tgaagtgtct gccatggaga taatatccgg
    28501 catatcttcg tgtgttacca attttggggt gatcatttgt actgttgctg ttcccgaagc
    28561 tacattcaca atttttaagt caatatttgc tccagttttg cggttataga tttttgcagc
    28621 attttcaaca tagtttgtca gtttgccgtt tgcgacatat acttctaatg tagtggcttt
    28681 ttttatcatt ggatctgcga tgtttgctgt tacttcttcg ttagtttttc cacatgcact
    28741 taagctgaat aatagggtaa tgtttagcaa agctatcacc aatttgtatc tttttttcat
    28801 gtctatccct tctttctttt caagttctta tataaaacgc tttcacttat gtatattaac
    28861 ggaattagta acacaaatat ttatataaaa aaatatttta cttgtcgttt tggcttttca
    28921 tttttgttat aatagtcatt aattataaat agaaagcttt ttatataaaa agagaaagga
    28981 aagtggttct tttgttaaca aacaaccaat cctccaatct tgtcaaaaaa acactaacct
    29041 attccataga tacccatctt catttatctg ctgctcccta ttttcgacta ctaataaatg
    29101 aaagcgctaa tttatatgct gaatttgcac ataaatctat agaactagat aatccttccc
    29161 ttttattcat tgataaacag caagaagtcc aaatcttttc tactcaaaag gaaacacaaa
    29221 cttttatcat tatccagttt tattttgatg agcaattatt agcacatatt acgggacaat
    29281 ctttttctat agatcaagaa ataacatcta tcattacttt tctgaaaaat gaacagttca
    29341 aaattgatta tctaaaacat agtaagccag ctatttccta tgatcaggaa atcaattctt
    29401 ttttcatact atgccaacag atgagcattc atttgctttc cttattagtt acttattgtc
    29461 tgcaaaaaat tcaattgtct tccttaccaa ggcattatca acaggaactt gctttattga
    29521 caataccttc aaatgagaaa gtcattccta aaaaaaagca tattctttat tcagatgaat
    29581 tagttgatcc aatcatacga tatttagaag aacatctttc agaaaatttt ttgcttgaac
    29641 aattagccca aatttttttt atcagtccag ccagcttaaa aaaacatttt agaaaagtga
    29701 atggaaaaag tgttattagc tattttaaag aactaaaaat ggaaaaagca aaacgtctcg
    29761 tgctagaaaa tgaattaacc tatacagaaa ttgcagatat attaggattt cattcgatcc
    29821 atcatttttc ttcagctttt aaaaaatata cagggttatc cccttcaaag tattatctat
    29881 ccttaaaata gaaaaaaatt tttaggtttt atccacaaat tatttctcta tattttctgt
    29941 ctattcaaaa taaacaataa ttttccggca caattatttg ctgtttttta ccataacata
    30001 gtacgatcaa cgtagaaaag gagatgtttt tatgaaagtt gttgtcattg gcggtgtagc
    30061 tggcggtcct tcatttgcca ctcgtttccg tcgattgaat gaagcgcacg aaatcattat
    30121 ctatgaacgc ggagaaaata tttcttatgc aagttgtgct ttgccttatt atttaggagg
    30181 tgtgatcact gaccgtgact cgctgatcga acgtacacca gaaatattga aaacaaaaaa
    30241 caacatcgat gtctttacta aacacgaagt aacagcaatc gatccttcta ctaagcgatt
    30301 aacagttaaa gacctatcca caaatgaaga aataaaaaca gattacgata agttgatcat
    30361 ctcttctggt gctagaccag attatccgga tattcccgga gtttttgaag cagaaaacgg
    30421 ctttgtcctc cgtagtgtga cggatgcgga tcgaatcaaa tcgttccttg aagaaaaaaa
    30481 tccacaacat gtcgtcattc ttggtgcagg tgttatgggt ctggaattag ctgagaattt
    30541 caagcatcgc ggcttagacg tgactttaat cgatcaattg ccacaagtcg ctttccctta
    30601 tgatccagaa attgctaatt tagtttatga caaattgctg aaagaaggat tagccgttca
    30661 tttagaaaca agagttactg agatccgtga taaaggtcga gaaatagtat tatcagatgg
    30721 ctccgtcctt tctgctgata tgctaatttt tgctgttggt gtttctccga agaatgaagt
    30781 ggtgaaagca accggcatac aattatcaga tacaggtcag atcattgttg atgaccagtt
    30841 acaaaccaat ctgccggaca tctatgcgat tggcgatatt atcgaaacga ctagtgtagt
    30901 gactggtcag ccgatccaaa gtatgctttc cagtgcggcc aatcgtcaag gacatatgct
    30961 ggcagatatt ttaaatggta cgcctatgcg ctatcgcgga tatattggtg caggtgtcgc
    31021 aaaaatcttt gatcatacag caagttatgc gggaatgaca gaacatgaat taaaagcatc
    31081 aggcataaca aattataaaa ctgtttttat cactcccttt gaccatgcct atttctatcc
    31141 agaagctaca agattaaatc taaagctgat ttttgatgca gatagcggtc gtattttagg
    31201 tggacaagca tttggagaaa aaggtgtcga taaacggatg ggagaacttt ctgtagcaat
    31261 caccggaaac ttgacagtct ttgatttgcc tgatttggag ttgccttact ctccaccgta
    31321 ttctactacc cgtgacccgt tgaatatagc tggttatgtc gcaatcaatc aaatgacgaa
    31381 tatcgtagaa acgatcaaag caagtgatat acccgaaaac gatttgaaag aagcgttctt
    31441 tttagatata cgtgaaccta ataaagcacc ttctggcagt atctcggcaa caaaaaatat
    31501 tccaatgaat gagttacgag atcgaatcaa tgaaatccca aaagataaaa aagtttacat
    31561 tactttcaga agaggattga atacttatac ttctgcccga atcttggcag gtttgggtat
    31621 caaagcgatt ttgattgaag aataaaaaaa cgaccgcggt gggtagccgc ggtctaggag
    31681 ttatttttac ttgaggagta aaaatgaaaa agtatatagg gttgttggtt ggtatgtata
    31741 tagaatagaa gataaatgtg aagaaattgt gcattatttc ttcacattta ttaggttata
    31801 gtttaagaaa gtttaaacat tgcgcaattt aattatttta gctgtttctt ttcataaaaa
    31861 aacatgttgt gactctgaga caaatcatag tccatagtga tgtctctaga gtaactacgc
    31921 ctaatattac gaggcatcat attaatctat cagcactagt acctaaacta gcatcccttt
    31981 cgaatatttt ttcttatata ataaagtttg ctttcactcc tctaatctca ccaaatcgac
    32041 tggcttgcgt tgtgtgatac taggaactga ttggtttaga acgacttttc tattgtaatc
    32101 atatttttcg ccatcctcgt tgtcttctaa tccttcaatg aatgatccct aatgtgtgta
    32161 ttaaataatt taattttttt gttcctattt atttaac
//
LOCUS       DAIGWC010000030        31503 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.030, whole genome shotgun sequence.
ACCESSION   DAIGWC010000030 DAIGWC010000000
VERSION     DAIGWC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.030"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            271..1140
                     /locus_tag="NOB74_001367"
     CDS             271..1140
                     /locus_tag="NOB74_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HCI1220563.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1349..2374
                     /locus_tag="NOB74_001368"
     CDS             1349..2374
                     /locus_tag="NOB74_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCI1220564.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2413..3363
                     /gene="manA"
                     /locus_tag="NOB74_001369"
     CDS             2413..3363
                     /gene="manA"
                     /locus_tag="NOB74_001369"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HCI1220565.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3457..5160
                     /locus_tag="NOB74_001370"
     CDS             3457..5160
                     /locus_tag="NOB74_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1220566.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5162..7195
                     /locus_tag="NOB74_001371"
     CDS             5162..7195
                     /locus_tag="NOB74_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI1220567.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7206..7646
                     /locus_tag="NOB74_001372"
     CDS             7206..7646
                     /locus_tag="NOB74_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1220568.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7846..8973)
                     /locus_tag="NOB74_001373"
     CDS             complement(7846..8973)
                     /locus_tag="NOB74_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220569.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8976..9653)
                     /locus_tag="NOB74_001374"
     CDS             complement(8976..9653)
                     /locus_tag="NOB74_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220570.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9917..11683
                     /locus_tag="NOB74_001375"
     CDS             9917..11683
                     /locus_tag="NOB74_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HCI1220571.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11698..12135
                     /locus_tag="NOB74_001376"
     CDS             11698..12135
                     /locus_tag="NOB74_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1220572.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12148..13299
                     /locus_tag="NOB74_001377"
     CDS             12148..13299
                     /locus_tag="NOB74_001377"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCI1220573.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13361..14059)
                     /locus_tag="NOB74_001378"
     CDS             complement(13361..14059)
                     /locus_tag="NOB74_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HCI1220574.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(14052..15404)
                     /locus_tag="NOB74_001379"
     CDS             complement(14052..15404)
                     /locus_tag="NOB74_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HCI1220575.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15627..17027)
                     /locus_tag="NOB74_001380"
     CDS             complement(15627..17027)
                     /locus_tag="NOB74_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HCI1220576.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17188..17925
                     /locus_tag="NOB74_001381"
     CDS             17188..17925
                     /locus_tag="NOB74_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HCI1220577.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            18050..18529
                     /locus_tag="NOB74_001382"
     CDS             18050..18529
                     /locus_tag="NOB74_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HCI1220578.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18526..19293
                     /locus_tag="NOB74_001383"
     CDS             18526..19293
                     /locus_tag="NOB74_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220579.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19523..20092
                     /gene="lepB"
                     /locus_tag="NOB74_001384"
     CDS             19523..20092
                     /gene="lepB"
                     /locus_tag="NOB74_001384"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI1220580.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20196..20798)
                     /locus_tag="NOB74_001385"
     CDS             complement(20196..20798)
                     /locus_tag="NOB74_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI1220581.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20904..21373
                     /locus_tag="NOB74_001386"
                     /pseudo
     CDS             20904..21373
                     /locus_tag="NOB74_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21479..22063
                     /locus_tag="NOB74_001387"
     CDS             21479..22063
                     /locus_tag="NOB74_001387"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HCI1220582.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22066..23139
                     /gene="prfA"
                     /locus_tag="NOB74_001388"
     CDS             22066..23139
                     /gene="prfA"
                     /locus_tag="NOB74_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HCI1220583.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23132..23971
                     /gene="prmC"
                     /locus_tag="NOB74_001389"
     CDS             23132..23971
                     /gene="prmC"
                     /locus_tag="NOB74_001389"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCI1220584.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23964..24143
                     /locus_tag="NOB74_001390"
     CDS             23964..24143
                     /locus_tag="NOB74_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220585.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24165..25190
                     /locus_tag="NOB74_001391"
     CDS             24165..25190
                     /locus_tag="NOB74_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HCI1220586.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25381..26625
                     /locus_tag="NOB74_001392"
     CDS             25381..26625
                     /locus_tag="NOB74_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCI1220587.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLHGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26778..27725
                     /locus_tag="NOB74_001393"
     CDS             26778..27725
                     /locus_tag="NOB74_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1220588.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27859..28488
                     /gene="upp"
                     /locus_tag="NOB74_001394"
     CDS             27859..28488
                     /gene="upp"
                     /locus_tag="NOB74_001394"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HCI1220589.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28627..28869)
                     /locus_tag="NOB74_001395"
     CDS             complement(28627..28869)
                     /locus_tag="NOB74_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220590.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28990..29062
                     /locus_tag="NOB74_001396"
     tRNA            28990..29062
                     /locus_tag="NOB74_001396"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29023..29025,aa:Thr,seq:cgt)
     gene            complement(29181..29819)
                     /locus_tag="NOB74_001397"
     CDS             complement(29181..29819)
                     /locus_tag="NOB74_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI1220591.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29942..30574)
                     /locus_tag="NOB74_001398"
     CDS             complement(29942..30574)
                     /locus_tag="NOB74_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCI1220592.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30925..31224
                     /locus_tag="NOB74_001399"
     CDS             30925..31224
                     /locus_tag="NOB74_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI1220593.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        10761 a         5484 c         6331 g         8927 t
ORIGIN      
        1 ccttaaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatag
       61 gaggagctat ttttgtttgg ctgttcttat tacttgatgc agaacagctt tttcacaacc
      121 tctttttata agagttttta ctcattaatt tacaaaaaac aagcaaaatg cgaattttct
      181 cacatttttt ttaacaaaat caaagttatt gcttgaaaga agaagaatcc atcgttaaaa
      241 taaagcttga cgtagagggg agcaagaaat atgaaagatt ttcaattggg ggctgccacc
      301 tatttaaaaa gtgtagccat tcgggtgaaa gaccgagata aaatgattga tttttacaag
      361 aacgttgttg gctttgattt gaaaagagaa gaaaacgaat tagccatttt aggaacagaa
      421 gaagctggaa gtgaaatgtt gctgctggaa gaaagtccta gagcgaatga tcacatgggg
      481 gtgatcaaaa agctgaaccg tttttcattg attatcccta gcacagaaga aatggcagat
      541 atcctttgtc gtatccgtaa aatgaattat ccaatcaaag aagctttaga agatcatgga
      601 cgtatgggga ttttgctcgt agacccagaa gagaatgaat tggaaattta ccatgaagag
      661 aataagaacg accaaagaga aattccagaa acaatggatc aagaagcatt attaagaaaa
      721 tctgaagaaa aattcagtaa actatcaaca ggttcttatt ttgaaaaaat ccatttaaat
      781 gttactaact taacaaaaga acgccaattt cttaatcatg tacttggttt gaaggtacat
      841 aatgaagaag agggcatcca tgtattgaat gaaggagatt tccatgttgg tttgacagaa
      901 gctagcggag gcgcaattga tttgcctaca gatgaagtga ttggacttga ttttctgaaa
      961 ttcatgatcg atactgaaag catggaagga ctgattgctc acttgcagca actatcagtt
     1021 gatttcttct tagacaaaaa gcacacagta ctcacaatct atgatgctat aggaatcgaa
     1081 tggtggttcg tcagtgagcc aaaagaaaag aataaaactg acattcgatg cgacgcttaa
     1141 ctttttcttt cttaacgatt gtcgcatgtc tcgtcatttt atgaacggtc atactatcgc
     1201 ttattctaga gatagaaaga gaaaatagta taccggggga aactgcgcgg tttttcgcgc
     1261 agtttttttg tgtaaaaaag gttgattcct catagattaa gctttaagct tggactgtaa
     1321 gaatctgata gaaaagcagg agaaaaagat gtatccacac acgaaacagc ttattttgaa
     1381 aaagatggaa gaaggatttt atccaggtgt agcagtcgcc ttcataaaag aaaatcaagt
     1441 agaaacattt acagccggct ttgcccaagt cgttcctgaa aagcagctga tgacagaaga
     1501 tctgttgttt gatgcagcct cactgacgaa agtcgttgca accacttcat tagttttacg
     1561 tctattagaa gatggaaaga tagaactcga tcaaccgctt cataaatatc ttcctgaatt
     1621 tgaaaatcag acaatcactt tgcgtcattt actgacacat acttctgata tcaaaacatg
     1681 gataccaaac agagataagc tatctcagga agaattgatc gccgcttatt tgaagctaga
     1741 accaggtgag caactaggaa aagaagtaaa atatacagat gccggtacga ttcttcttgg
     1801 gttgatgcta gaggaaattt accaagaaac tgcagtggaa atctttcaag aacaagtatt
     1861 ggaaccatta ggaatgatga acagcttatt tcttcctttt ccttccaaaa aaatcgttcc
     1921 cacagaacaa ctgccttcgg gtgaggtttt gcgtggacaa actcatgatc cgaaagcaag
     1981 agttttggct gaacatgcag gtaacgcggg tctctttatt gatttgaaag acagcattac
     2041 ttttgtccaa atgtatttga acaagggaaa aatccgtaat ggtcgttttt tagaagaaga
     2101 gacgattgat tctttactgc aagatcaaac accgaaaaaa aatggctatc gttctttagg
     2161 atgggactta aaaaaggatg tagaagacgg tcatgcgatt ctttttcata ctggttatac
     2221 aggtacgttt ttcttgattg atataaaaac acaagaagcg ttgatatttt tgtcaaatcg
     2281 cgtacatcct gtcgatcatc gtgcggagta tctcatatgt cgagatgaaa ttgttgaaaa
     2341 ctttttgaaa gagaaagcgg tattaccgaa ataatgctat aatagctatg aaaaatgaga
     2401 ggagtttgaa ttatgcagga acctatgttt ttaaaaccag tttttcaaga aaaaatttgg
     2461 ggaggaagtc gtttacgttc agtctttggt tttgatatcc ctaacgataa aatcggagaa
     2521 gattgggcga tcagtgcgca tcctcatggt gtcagtgtag tagaaaatgg cgaattcaaa
     2581 gggaaaagat tagatgaact atggtcagaa cacaaggaat tgtttggcca tccttcagaa
     2641 ccagtgtttc cattattgat caagatctta gacgcagaag atgatctatc tgtacaagta
     2701 catccagatg atgcctatgg gatgaaacat gaaggtgaat taggaaaaac tgaatgctgg
     2761 tatatcatcg atgctgaacc tggtgcagaa atcatctatg gtcatcatgc aaagacaaga
     2821 gaagaactag ctgagatgat caaagatggg cgctgggatg accttttgaa gaaagtacca
     2881 gttaaaaaag gtgatttctt ttatgtacca agcggaacga tccatgctat tggtaaagga
     2941 atcatgattt tagaaacaca gcaaagttct gacacgactt accgcgtgta tgactacgac
     3001 agaaaagatg cgcaaggaca aacaagagag ctgcatatcc aacaatcgat cgatgtaaca
     3061 actgtccctg cgaaaacacc agaattacaa atcaaagaag tccgaaaagg gaattcatcg
     3121 atcgtcactt atttagaaac tgagtttttc aatgtatatg agtgggatat taaaggaatc
     3181 acatctttca aaaaacaagc cccttataca ttgatgacgg taatcgaagg agcaggagac
     3241 cttgtcgttg acggaaaaac atatccatta gaaaaaggaa caagctgtat tattccaaat
     3301 ggcgtttctg agtgggcggt ccaaggtgaa ctagcaatca ttgcgtctga accaggcaaa
     3361 tagttcccag atagctgaaa gcagcagacg gtttttcgtt tgctgctttt tctacataaa
     3421 atccgtccat caataaatag aagtctggtg aaaaagatgg aatacaaatg gaaagcaaac
     3481 aacagcagtc gcgtgtctat gaaacaactg agaaaagctg gacatcactt aaatgaaatg
     3541 atcatgccaa atctaagtct gtttatcgct tggggaatct tgtcattagc aacaaaaggt
     3601 gtgtctggcg atttgcacac cacattagaa gaggtatgcc attggatgat ccagctgctt
     3661 ttacccatct tgatcagtta ttcaggcggg aaatcggtag ggggacaaaa aggggcagtc
     3721 gccggtgcaa ttgcttcttt agggttgatc gctcgttcca atgctccaca aatcgtagga
     3781 gcgatgatta tcgggccgct tgccggcatc gtatatgaac aatttgtttc tagattccat
     3841 gtgaaattca aggctggata tgaaatgctt gtcagcaacc tactagtagg actgactggt
     3901 agcgttattt gtataattgg aatcgttttt attgaaccag ttttaaatag tgttcacttg
     3961 ttgctcgcct ccgttgtgtc ttggctagtc acaatgaatc tgttaccact tgtcagtctg
     4021 atcttagaac ctctaaaagt actatttttc aataatgcaa tcaatcatgg tgtattgaca
     4081 cctttaggaa tcgaattctc acaaacagtc gggtactctt ccttattttt gatggaggca
     4141 aatcctggac ctggtttagg gatcttactt tctatccttt gttttgcaga aaaacaggaa
     4201 aaagtaaatg cgagtggagc attgatgatc catgcgattg gcgggattca cgaaatctat
     4261 tttccatttg tcttgctgcg accgtatcta tttttagctg taatggctgg tggggcaagc
     4321 ggcacgttga tatttcaatg gttagatacg ggattagctg cacctgtatc gcctgggtca
     4381 ctactcgtga tttttgccaa tgcgccttat ccacaactag ctggggtaag tatagggata
     4441 gcaatcagta catttgtgac cttcatttgt gcagcgatac tattgaaatt accaaataaa
     4501 gaaaaagaga acaaaacggt caaagaaagg ggagaaatct tggaaccatc tatcattcat
     4561 tccgtcattt ttgcttgcga ctcaggtatg ggatcaagtg ctatgggagc cgccctgctg
     4621 aaaaagaaat tagcagcaga aaaaatcgat ctttctgtcg gatacagctc tatctatgaa
     4681 ttgaataacc aagtaaatca gctggttatc gtgcaacatg aactagcggg tcttgcaaga
     4741 gaaaaagtac ctcaaagtca aatctatgta ctggatcact ttttggaaac agatatcttg
     4801 ctgtcacgaa taaaagaagc gatccaattt ccaaagcggg aagaaaaaaa agagatagca
     4861 gatatcacag aacaaaaaac gtcgcctgct aatattgtat ttttgtataa aaacaacaga
     4921 cgcggctcac aaactatggg catgacgatt ttaagtcaat tagcaaaaaa agcgaaaaaa
     4981 cagtttgtta tctcaaaaga atcaatagaa aaaatcaaaa tccaagaaga aacgatttat
     5041 atcgcacaaa gagaactagc tgtaactgaa cagctagaag aaaagatccc tcggctagtt
     5101 ctagttgaac attgggtagc tacgaatgaa tacgaaaaac tcgtgaaggg agaaatataa
     5161 gatgtattta tcgcccagag aaaaacaatt attagcagaa tttctcagta gcccgtcacc
     5221 tgtatctatc caaaaaatga tgaatttatt gaaggtcagt aaacggacta tttaccgcga
     5281 attagataat cttgaagtct cattgaaatc ggtaaatgct tctttgaaaa aagcagctag
     5341 aggctcattt gtcattgagg catcagaaga agtattagag caattaaaag aaaatacaga
     5401 tgggaaaagt aatgacttat ccactgctaa acgacaacac gcgattttag ccgagttgtt
     5461 actgacgaca gagccgttga gtcttgctca tttcatggaa tcatatcgca tcagtaatac
     5521 cactttttat gcagatatca aacagttgga agaaagtatt cgccaactgc ctttggaaat
     5581 cattcggaac cagggatacg agatcgaagg accggaaaaa taccgccggc ttctgacagc
     5641 gaatgtatta gaattagaaa tcaatgaata tgaacttttt catagtattt ctttcgatgc
     5701 atcactgaat tatttttttc gattcgttga tccgcaacat ctatctcttg cacgcaaagt
     5761 aatcggggaa gaattgatcc aaaaaaagac caatctaagt gatagaaagc ttgaacattt
     5821 ggttttgatg ctgacattga cgatggagcg tgtgacgaaa aatcatttac tgacaaatga
     5881 gacatataat agtctggcaa acaaagaatt actacagaca gctaaacgat tgttttcacg
     5941 gatcgcttct gagacaaaac aactttatcc agtaaatgag atcgtctttt ttgcaggatt
     6001 attaaatgac ttcacgaact catttgatca gaatttcttt gaagagacgt tcgatacaca
     6061 gcttgcttat ttagtaaaac aactgattca agaagtaagt gaagagacga atgtccattt
     6121 ttatgaagat gaaactttgt acaaaatgct gttgactcat ttatctggtg tgttttcaag
     6181 agccgtttta caagaagaga cactgaccaa tccgatttta gaaaaaatca tggttcaata
     6241 cgaggaagtt gcgaatgcaa tccgtaaagc agtagagcgg atttttcaag aaaaaaaatt
     6301 atccgaagaa gagatcgctt atatggtcct tcattttgcg aattcattgg aacgaagtcc
     6361 gaaagaaagc aatatcagta ttgcaggatt ttcgccaagt ggattagctt ctactagcat
     6421 gttggaacta cgattgaaaa ggtattttcc cttcatccaa caaattcatt tctatcggat
     6481 tgctgattta aaaaaaatcg atttacaaga agaatatgat gttgttattt ctacatctat
     6541 tttaccagga tacggtggaa aatatatttt agtctccccg ctactgctag aagatgaagt
     6601 caagcagcta aaagaagctt tttcgcatat tgagaagaaa aaaaggcaaa aaattacgta
     6661 taacagcaat aacgagtgga tgatagaaga tacttatgag gaaacaatgc atttcatgga
     6721 tcaaatcaat caattactcg gtcgtttttt tatccaagaa ctggataatc ctgagacgat
     6781 ttccgaaacg attcgcagct tatttcctta ttttcctgaa ggactagtaa cggatgaaga
     6841 ggtggttcat cgccggctgc ttaagcgata tgaacaagca cctatcggta ttcctcatac
     6901 aaatatgggg ttattccata catccagctc attgatttct aaaccgatct tttgtatttt
     6961 caatttgaaa catccgttga ccattgaagg gatggataga cagccagtcg atttgtcccg
     7021 tatgttagtt atgctggcgc cttcgccaat ccaagaaaaa gacgggattc ttttaggaaa
     7081 gatcagtgga gcaatcatca tgaatgactt gaacaccgag atcttccgct caggaaataa
     7141 agaaatcgtt tatcagttgt tagcgaaaat cctgattgaa gaaataaaga aatgaaggtg
     7201 aaaagatgat acagctacca gcagaaaaaa tattgctcga tcaatcctat caaaattgga
     7261 aagaagcgtt gaccgagatc ggccagtgga tgacccaaca agggggaatc aaaccggcat
     7321 atatccaatc aatgatcgaa agacaagaaa aagcgagtgt ctatatcggg aatttcgtag
     7381 ccttgccaca tgggactgac aaagatgaag aagtagtaga agaaggaatc tatttagtcc
     7441 aagtgcctga tggtgtggac tttggaacaa aagaggaacc aaaaatcgcg acactcttat
     7501 ttgtagtggc tttaaaaaaa gaacatcagt tagcggtgct ccaagattta gcctttttct
     7561 gttcagacat cgaccaagta atggcgctca gtgatgcgga aaccattgaa gaagtccaaa
     7621 tgatttttga acatggacat atataaccaa tgttcacagt aaaaaaagct gccttgcatc
     7681 aagtaataac ttcaaccaag ataaaaataa gaggagctat ttttgttggg aggttcttat
     7741 tactgcggat gcaagctttt gaaaactatt tattctagaa aaccgtttat ttgaaatagg
     7801 ggacggtgac aaggtttttg tcaccgcccc tattattttt gtgttttaat agctcttttt
     7861 tatatagata gtgcccatac ctatgaataa taaaacgata ctccatatac caagtgtcaa
     7921 gataccattc atgaaagtaa cctgttctga agctagtggc gagaaaatat ctcctcctat
     7981 gatcacattt tgaaaatcaa cataagaagt tggcaagtaa tgactgattg attctatcca
     8041 tccaatcgaa gaaaacaagc gatactctgc taagaaaaga caaagaagtg tacctaaaag
     8101 attgactaga gaatgttcaa ataaagcaga tagaagaaaa ctgattgtac ttaaaaagag
     8161 cacccacaac aacaggaaca gaaagctctg gaaaagatac tcatacatcg gcaggattcg
     8221 tatctcctga ccaatgatcg ttcctacagg ataacggaag tctcccaaac catttttgat
     8281 tattactagt atagagacga tcaaaaatgg catcacgaga cttagcatag ctgcaccata
     8341 ataaatggta aaacggatgc tatgtttctt taccatacta tccagtaata gattgactag
     8401 agagattacc tgctttcttt tttcataaga gatgatggaa gaaagaaaca aggcggttat
     8461 acataaaatc aaaaaactag aaatcattcc tgaaaaaata ttttcgtagt aatttgctaa
     8521 agagagatgc gctggcaagt caaaaataga atatctttgg atctgatgtt ctttcatata
     8581 acggagcaac tcgacacgtt tttgttgttc aatgattgga attccttgtc tttgaccaga
     8641 aatcagtcga tccagtatat ctttttcata atgataagtt gcttcgacca tttgctggac
     8701 attccctgtg ttttttgcat gtaagattgc ttcgatcagt ttgttgcttt tctctaaact
     8761 ttccacaaat tctttctcat tctcatcttc tttcaacgtt tcaatcaaac gttgcatctc
     8821 ttcatagtta tgattcagtt catcgaattc tgtataagca agtttatgat caaaaaaaag
     8881 tgggaatgca aagagcacga ccaacaatag aggaaataaa aagtttactt tgttttttag
     8941 taagagattg cgttcaaatg taagtaaaga catagttaca cctcatataa tttacgataa
     9001 atagctaaaa tctcttccat atttgaggat tctgtgacga tttctccatt ttttagaaaa
     9061 catgctttag aacaaatcga ttggatattc gcgatagcgt gggaagaaag aagaatcgtc
     9121 ttcccctctt tctgccattg tctgatgagg ctattcaaga tatcaatact tcctgggtct
     9181 aatccgttca acggttcatc gaataacatg acagatgaat cactgatcaa gtaagcagca
     9241 agcaagacat gttgtttcat tcctagagac atttttccaa tcggcaaagt aaggtactca
     9301 gtcatcttca atcgttggaa aacagtttgg cattctactt tgctctgcca atagtatttg
     9361 atcaaagtca aataatcaac agccgataga tagtcggata actgattcgt tgattctaga
     9421 aaaaagaaag accggcgata atctgtataa gcagtaggag agatgttgtg aagggacaat
     9481 tgatcataag ttgttggcag cagttgggca atgccattca gcaaagttgt tttgccaaat
     9541 ccgttcgggg caatcaaagc agctacttct cctgattcta ctaaaagatt caattgtcga
     9601 atcacacgtt ttttaccacg tttcatgttc atgtttttga tcagtaatgt catagatagg
     9661 cctccaatat aaaatttaat aacataatag aatggaaaac atctaaatta aatgctaaca
     9721 aaagttattg tttgcatatt ataaaaaaat taaaataaca gttttattta aaattgaagt
     9781 tttctgatac cgaaatcttt ttattttgct gacatactca aacctttggc acaaagtttc
     9841 gtgccaaagt acgactattt ctctttttag taagcggata caattagagt atcaaaagga
     9901 gagagggaga gacaaaatgg aacggacgat tcccaaaaac aacatttcgc taaaagcgag
     9961 ggtacaaaaa ttaggcagta ctttatcaag catggtcatg ccaaatattg gagcactgat
    10021 tgcctggggt gtattaacgg ctctatttat cccagatggt tatttaccaa atgaggcttt
    10081 cgctaccatg gtaagcccaa tgctaactta tctgattcct ttattgatcg gttatactgg
    10141 cggaaaagta attgctggtg accgcggatc agttgttggg gcaattgcaa cgatgggtgt
    10201 gattgtcgga acagatattc caatgatgct aggcgcgatg atcatgggac ctcttggtgg
    10261 atatgccatc aagaaatttg atcagctatt ccaaaaacgg atcaaatccg gttttgaaat
    10321 gctagtcaat aatttttcag caggtcttat cggttttgga ttagcgttat taggtttttc
    10381 tgcgattggt ccagttgtcg atgcattgac tcaagcaatg gcaaaaggtg tagagatcat
    10441 tttatctgcc catttgattc cattgacaag tatttttatt gaaccagcaa aaatcttatt
    10501 tttgaataat gcaatcaatc atgggatttt gacaccattg ggaactgaac aagtagcaga
    10561 ggctggaaaa tctattctat tcttgcttga agcaaatcct ggtccaggac ttggcgtatt
    10621 acttgctttt actttgtttg gcaaaggagc agcaaaatct tcagcaccag gagccatgat
    10681 cattcacttt ttaggcggga tccatgaaat ctattttcct tacgttatga tgaaaccgtt
    10741 attattctta tcagttatag gcggaggaat gtcaggaagt ttcattttcc aattgatgga
    10801 tgctggacta agagcgccag cttctccagg gtcgatcatt gcgattctag cgatgacacc
    10861 gttcaattct taccttcctg ttattttggg cgtgattgtt gccgcagctg tttcgtttgg
    10921 tatttctgca gtaattttga aagcggatgc gaaagataca aatgaagact tcgaaaaatc
    10981 tgttcaagag acaaaggcag ctaagcaagc ttccaaaggt gcccaaggta ttcctcaagg
    11041 agctacattc tctggcgtac aaaaaatcat ttttgcttgt gatgcaggaa tgggatcaag
    11101 tgcgatgggc gcttcgatct tgagaaaaaa agtacaggaa gcagacttgc ctcaaacggt
    11161 gaccaatcaa gcaatcagcc aactgacaga tgactcgaat acattgatcg ttactcaggt
    11221 cgaactacaa gaaagagcaa aacaaaaagc accgagcgcg cgttttgtct cagtagaaaa
    11281 ctttttgaat tcacctcgat atgatgaaat cattcaagaa ttaagcagca agcagaaaac
    11341 atcagtttct gaaattgaga atgagccagc agaagagttt ctttcagcaa acatcaaaca
    11401 aatcaaagag attctacttg tccacgatga tcgttccgga tcagcaacaa tggggatgac
    11461 cgtgctcaaa gatatattag acaagaacca tttaactatc ccgttaagaa aagtcaatat
    11521 ccaagattta aaagatgaac ctgattcact gatcgtagcc aaagaaagtt tagcggaaaa
    11581 agtacagatg gctgcacctc aatccattca tttatcagtc aacagcatgg tcaatccgca
    11641 aaaatacgaa tcgattgcac aatatttgaa acagacagct taagggagga aaacagcatg
    11701 caaagtttgc cattcgacat gatcgagctc aatcgatctt ttaaaaccaa agaagaagcg
    11761 atccgctatt gcggtcagat gcttgtagaa gcagggtgcg ttgatgagga atatatcgat
    11821 gccatggtag atagagacaa aatgttatct gtttatatgg ggaattttat cgcgattcct
    11881 catggaacag atgaagcaaa aaaatatgtg aaaaaatccg gcatctgtgt cgttcaagta
    11941 ccagatggtg tagattttgg taccgaagaa gaagaaaaga ttgcgactgt tttgttcggt
    12001 attgcaggag tcggagatga gcatttgcaa cttgtacagc aaatcgcact ttattgcagt
    12061 gatatggaca atgttgtcca gctagcagac gcgctcagca aagaagaagt aacggaaaat
    12121 ctagcaattg cttaaggaga gagaaaaatg agagcagtac attttggtgc aggaaatatc
    12181 ggtcgaggat ttattggaga ggttttggca gctaatggat ttgagattac tttcgtagat
    12241 gtgaatcaca cgatcattga tgctttaaat gaaagaaaag aatacgaaat cgaattagca
    12301 gatgaatcaa aagaaaaaat cactgtaaaa aatgtcaaag gaatcaacaa tcaaacaaat
    12361 ccagaaaaag taatccaaga aatcgctgaa gcagatttag ttactaccgc cattggcccg
    12421 aatatcttac cttttattgc tgagttgatt gcaaaaggta tccaagaaag agaaaaggaa
    12481 ggaagcacaa catctttaga tatcattgcc tgtgaaaata tgattggcgg ttcagcattt
    12541 ctagaaaaag aagtgtataa atatcttccg gaaacatcat ttactgacaa atatatcggc
    12601 tttccaaatg cagcagtcga tcgaatcgtc ccattacaac accatgaaga tcctttattc
    12661 gtccaagtgg aacctttcaa agaatgggtc attgacgata gccaaagaaa aaataaaaaa
    12721 atccaattaa aaggggtttt atatgtagat gatctagaac catatatcga acgcaaacta
    12781 tttagtgtca atactggtca tgcgactgtc gcttatacag gtgccttgtt aggttaccag
    12841 accattgatg aagcaatgca agatgcgtta gttgtggcac aattaaaatc agttttgcag
    12901 gaaacaggaa gtttgctgat tgccaaatgg gggtttgatg cagagcagca tcatgcgtat
    12961 attgaaaaaa tcattcatcg cttccaaaac aaaaatatct ctgatgcgat cacacgtgtc
    13021 gctcggacac cattacgtaa gttaggttat caagaaagat ttacacgtcc agtgagagaa
    13081 ctacaagaac ataacttgac ttgcccacat ttgacggcaa caatggggat tatttttaat
    13141 tactatgatc ctgaagatga acaaagccgt caattgcatg aaatgaagat ccatgaaaac
    13201 ttggaacaat tgattcaaga agtcacagga atcaatgatc cgaaaacaat cgggaatatc
    13261 aagcaaaacg tgaaccgtta tgccaagcaa gtcgcttaaa ataggatacg aaaaagggga
    13321 atgtgacgaa atttttgtca cattcccctt tttcgaataa ctaggctgtt tgtccttcaa
    13381 gatagggcag atccaattct ttaccgtaac gttgttctaa agctaggcgg atcaaacgag
    13441 ctgccaggtt ctcatttctt gcaaggatag gtccatggaa ataagaaccg aagacatttc
    13501 ggtaaatgac accttcagat tggtcttcac cattatttcc ttgaccttgt accactttcc
    13561 ccaaaggtcg ttcaccttca cctaagaaag tccgaccatt gtggttttca aatccataat
    13621 aagtttcatt gaattcttcg ttatggataa cgatatcacc gataaaccgg ttattttcct
    13681 gacttaacgt gtagtgatcc agtgcactga ttccttggat cttttctcca ttagctccca
    13741 tgtagtagtg acctagcaat tggtagccac cacaaatggc taacatgacg ccatcatttt
    13801 cgatatagtt gatcaaagaa tctttctttt tctggatgtc ttttgaaatg attaattgct
    13861 caaagtcttg accaccgcca aagaaaacca agtcatattt atcagcatca aaaggttcat
    13921 gtatactaac gatctccgta tggcaagaaa cccccatttt ttctgctata tatttcaaca
    13981 tcaaaaggtt tccgttatca ccatatgtgt tcatcaaatt tccataaagg tgggcgatat
    14041 tgagttcata attagccacg gttcattcct cctttgataa atccttgagc agctagttct
    14101 ttacgaagct gcaatacagc agtgtaagta gctaaaatat agacatgctc agttggcaat
    14161 tctttgattt tttcgattac ttctggtaat tcttttgttt ctgtcaattt attttctgga
    14221 atcccggcaa cttttagacg taaagtcata tctgtatgac ggtctcctcc agaaataaca
    14281 gctgggatat ccatatcggc aaagttttca aaattaccat cccaaatcca gctgacatcg
    14341 attccgtctg cgtaattggc atttaataaa gccactaaag aaaatggata aggagctaga
    14401 ccaatcatat cgattacttg attgatacct acaggatttt tgacaagtac taatgtacat
    14461 tttttcccat tgatattgat gacttcttgt cggccgaata ctttctcgtc atatcctaaa
    14521 ccttgtttga ttttatcagg atcgacattg aagtactctg ccactgcagt agctgctaaa
    14581 gcattgtaga cattatacat accgccaact tcgattccgt attcatgacc atcgatcacg
    14641 aaatctgctg acacattgtc catccgtacc atatcagtta atcgataatc caattcagga
    14701 cgtttgaagt cacaatttgg acagtaatat ttccctaagt ttgcataagt gatcatttta
    14761 taatgcaaga tgtgatgaca atttggacat aagacaccgt ctgtattgta atgagccatt
    14821 tgttcacgat cttcttcatg gtcaaagcca taatattttc taggattgac tgtttcgata
    14881 gaattgaaga ttggtgaatc accgttactg ataatcgttg catttggtga ctttgcggca
    14941 ccgtctacaa tcattttata ggtcgtatag atttctccat accgatccat ttgatcacgg
    15001 aaaatatttg taaataagaa cagttctggt ttcatatatt ctgtgacttt gctcaaactt
    15061 gcttcatcta tttctaggac agcaaacttt ttctgtcctt tttttggttt tgcctgcaag
    15121 aaagtcgata caattccctg taccatattc gcaccagtag ggttggttag aacttcatcg
    15181 aattgctggc gcaaaatatt gactgttaaa gcggtagtca atgttttacc gtttgttccg
    15241 gtgacaacga cgacttggta gtcttttgcc aaactatcta gtatatgtgg atcgactttc
    15301 agcgctagtt tacctggtaa acttgatccg cctttaaaaa aagtttttaa tgcccattgc
    15361 gacgtttttc caactgcaat cgcaaaatga ctgcgtattc ccattatgta acctccaaaa
    15421 acgatttgct gacgaataaa ttcaactaat cataccatat gttgaaaaaa aggttaaatt
    15481 gcttttctta ttcttaagaa aaggttacgg ctgaaagtgc atgaaatcgg acaaaatcgc
    15541 atgatttaac aaaaaaacag cttgaaacaa aatgattgtt tcaagctgct gtgattttat
    15601 tattccctct tacctatatt cccattttaa ccgataataa ttttctcgct tggatattca
    15661 tagcctagat ctcgtgtttc ttttggcacg aataacatca atgtatatag cattccgatc
    15721 cgcccaataa acatcagtgt agcaatcgtg attttgccca caacagacaa gtctccggta
    15781 atccctaaag ataaaccagt tgttccaaac gcagaagtta cttcgatgat gatcgagatc
    15841 agcgtttgtt cttctgtagc agataaaaaa acgatacaaa agaaacacat accaagagaa
    15901 agcataaaga caacgactga ttttcgcaca tcatcttgat cgattctccg tccaaaaata
    15961 ttgatgttat cttcactttt gaggaaggaa tatagataca aaccgatgat tgctacagta
    16021 gttgttcgaa tcccgccgcc tacagaacta ggactgcatc cgataaacat cagtaaagaa
    16081 aaaatgatca gtgttgtgat ttgaaaatca cccaaatcgt gaatctgcag accagcatta
    16141 cgagtcgtaa tcgaataaaa catcgaattg atccatttga cactcatatt ggaatcttgg
    16201 aataaatggt ccttttccaa tagataaatc aagacagttc ccgaaacaaa caagataaca
    16261 aaagctaaca cagctaattt ggtaaacaag gaaaaacgaa acggaagctt cgcattggaa
    16321 cgtttgtata atagccattc ccggcactcc atcaatacag gaaaaccaat tcctccgaca
    16381 aaaatcaaaa acatgatcag gatcaagaaa aaatagtcat gtgcaaaggg cttgatggaa
    16441 tccccagtga cgtcaaaccc agagttcgtg acagccgata tcgcctgata aaaaccgtaa
    16501 aaaacggcat cacgccaacg atcaaaatag cctctgtaat aaaaataaat agaaaagaat
    16561 gtcccaaaaa gtaattgaaa ccagattaaa atagcaaaag tgatccgaat cagtcggacg
    16621 ataccagaca aacgcggttg attcatatcc gtcatgatca gctgtcgctg tttcagtgtg
    16681 atccgtcgtt tagaaaaaat gacaaaagca gtagaaatca tcatgatccc caaaccacca
    16741 acttgaaata atatttccag cagtataata ccgttatcat tgaacacaga attgatatca
    16801 aaagtcgata gtccagtcac actcactgta ctgattgcca tgaacagcat gtccacaaaa
    16861 gaaacatggc tatctggttc gcgaaaaatc ggcatataaa atagaacgag tgataagacc
    16921 gtcatcaata tataataaaa aacgatgatt tggatcgatg agaaatgatt ggcagcaaac
    16981 ttctgtcctc gccgctgcag ccttcgaaag aataaatcaa catgcacagt actatcctcc
    17041 tgacaatagt cgtttctacc agtatacaag gggaattagg aatactcaaa gaaattatca
    17101 aacagataac aatacagctt tcgattaaaa tagaaatggc ttataataag gaaaatccta
    17161 gaaaaaagaa ggaggaggaa taacaaattg attaatgctc aacaaatcgt agaaaaaatg
    17221 aaaaatcaaa aaataaatta tgatacagtt ctgaaaaaaa tgatcatgca atgggagaaa
    17281 gaagaagtaa agcctaagat attaatacat acatgctgtg ctccttgcag tacgcacaca
    17341 ttggaattca tgtctcaata tgcagagatc acgttatttt tttcaaattc gaatattcat
    17401 cctaaaagtg agtatttgcg aagattacat gaacaaaaac gatttgtaga ccaatttaat
    17461 gagaaaactg accatcatgt tgcgctaatc gttgatgaat accgtccaaa tgaattcacc
    17521 aaaatggttt taacaaacca tcttgaaaac gaaaaagaag gtggtgctcg ctgcagtgca
    17581 tgcttcaata tgcgattaga tcttgttgcg caaaaagcgc aagaactagg atacgattac
    17641 tttggaagtg ccctgaccat ctcgccaaag aaaaatgcag ctttgatcaa tcagatcgga
    17701 atggatatcc aaaagattta cgggacacaa tacttgccaa gtgatttcaa gaaaaacaaa
    17761 ggctatgaac gctctttgca aatgtgcaaa gagtatgata tttatcgcca atgttattgt
    17821 ggttgcgtgt tcgctgccaa gcagcaagga tgcgatctga aagaaatcaa tcgggaagca
    17881 aaagcttact taaaaacatc aaccgtagtt tttgaggaaa attaaagaaa tctttcggaa
    17941 aaacgtaaga aaaaaataaa gaatttatgg tagaaataag gtagactgta taatttgtcc
    18001 gtagtaaagt aaggaaacaa gaataaattt caatgaagga agagataaga tgcgaaaagt
    18061 agcacctatt ttgaagccaa tcgctgtatt aacaatctcg acgattgtcg cgactactac
    18121 aggtattgtg aatagttcca gctaccgtgc accaagttca agttctagta ctgtagaaga
    18181 aacaacacca actacttcag tctcgacatc tgaaccaaca acaacggaaa gtttgaatga
    18241 aaccactacg acaagtacat gggacgatac aacaactagt tcgtcgtatg atgagacata
    18301 tacaactgac agctcaagcg aaacaagtaa tacggtacca gatggcactc catcggattc
    18361 aaccaatcca agtacaagtc cggatacaag tgctagctcc gaaacgatac caagcagtac
    18421 gactgtagat gataacacgc aaaatgatga tgcagcacgt acagcacagc aaaaccaaga
    18481 ttcaggaaat acccaaacgt ataaccagca agcaggtgat tctcaatgac atttttacta
    18541 gaccttatca acggggtgca taaattcctt ggctatttag acatcagtcc taaatatctt
    18601 aaccgtggat atacgatttt aagtgtgatt cccacgcttt atttattgag aattgtttat
    18661 ggactttggc aaaaccaaaa ctatcttcaa tttttcttat atggacttgc atttctagtg
    18721 cttgtttatt ttactgtttt aaatgtattt tattactttt tagataaaaa cacgaaagcc
    18781 gatgtcactc agctttttgt gaagtattta cctgatgaag cgttcaacat ccagacagaa
    18841 gaatcgatag ataatggaaa ttcgatcgat aaagtgaata cacaagaggt catggtttct
    18901 tatgacgaag attatcaatt gaaattagcc gagaatatgc ggtatttgat tggaaatggt
    18961 gagatcaaaa caaatgaact cggtcgcatg gatggatttc tggtcgatag aaatacattg
    19021 tatccttatt actatgtcaa gaaaacagga gagaaagagt atgttctaaa tattggacga
    19081 agctactcgg acatggaaaa agtagggacc attcgacttg actcaacaga agacacattg
    19141 gaacctgtcg gattgttcat cgtcggcggt gattttgtca aagacgggtt acgctatcat
    19201 gagccttatc gtctgaaatt gattgcaaaa aaggcacagt cgcaggaaga accagtggtt
    19261 tatagtcgta gccaaagaag aagacattca taatgtgatg aaacgccgtg tatcagtggt
    19321 tgcgataaaa acgtttattc ggaataaggg ggatgtgaca cgtcttttgt cacgttcctt
    19381 ttttatataa cgagaaagat aagacgaaca catcacttat tctttccttt catttataaa
    19441 cattgtagaa taaagaaagt acaacgaagt attgtgaaaa aacgtaataa ataacgagga
    19501 aaatacaagt aggaggtaag ctgtgaaaga atttttgaaa aattggggga ttttgatcct
    19561 tgtattagcg gctattttat tagctagagt gtacgtgttt acaccagtta ctgtaaacgg
    19621 gcattcgatg gaccctacat taagtgatgg acaacgattg atttcatcta agatctcaaa
    19681 ctatgaacga atggatatta ttactacaaa ggaaccgggg gatgaagaac ggatgattgt
    19741 taaacggatc atcggtatgc ctggagatac agtcaagatg gaaaatgacc agttgaccat
    19801 taatggcaaa aagtatgatg aaccttatct ggatgagttc aaaaaagaat tttcagaaga
    19861 taagttacaa ggagaatatg cttatagctc aggattccaa gcacaagcag aaagttcatc
    19921 cacctttacg agtgactttg aatatactgt gccaaaagga aagtatcttg ttctaggcga
    19981 taaccgcttg atttcaaaag acagccgaat gtttgggtta gtcgacaaag atatgatcca
    20041 aggaaaagtt gttttccgtt attggcctct ttcagaaatt aaaatcatgt gatgaaaaaa
    20101 taaaaagaag ctgtgacatg ttttttgtca cagcttcttt ttccgaaaat tccttcttat
    20161 ttcttggagt tgctcacttt ttttgcaatc tcattttaag ctttttggct gatggataag
    20221 aaaagcgaag cgtttttgtt cataaatagc ttttccccac gatggaaggt atgactagta
    20281 gcagagacaa agcccgtttt ttccaatcga ttattcaatt cttcttggct aaagccatta
    20341 tggactttcg gatgactaat ttgttcattc ttgtcaaagt ctacgatgat caattgaccg
    20401 ccaggagcta aaatttcata aagttttgta agaatattct ccgtatcagg aatgtgtaaa
    20461 agtacaagtg atagaaggat gagattagct tggacagcag gaaattcgac agaagcatca
    20521 gcgtggatcg ttcggacatt tttcagatct gctgcttgga tcttttcttc tgccattttc
    20581 agcatagttt ctgaagcatc ggcaatgatc agttctttga atctttccgc aagcggtaaa
    20641 ctaacaagcc cagttccgcc tccgtaatcc agcaggactt tttggtggct gtcgcgcggt
    20701 agataagtag ttagttcttc gcgaataatc ttggctaatg cttgacggtc aggggaatca
    20761 taatggttag cgatggaatc aaaaatattt tttgtcatca aatagctcct tacgtaaaac
    20821 tttgaaattt taacttatta tagcacgtga aaagaaagaa agcatgctat actcaattca
    20881 aaaagggaga atctagaaag aatatgccga tatcgtttgt aaaagataga gaggaaaaag
    20941 gaaagtgtgt ccgagaaata ttactagact tgcctgagtg gtttgggctt cctgaatcaa
    21001 cggaaaaata tatcgaggaa tcaagtaaac tacctttatg gtgtgaaaaa agaaaagaag
    21061 aatatttagg ctttatcact ctttcacaga caagtgaaga tactgccgaa atctattcta
    21121 ttgtatggga ataaaaaaag actatcatca ccaaggatta ggaacaaaac tttttaaaga
    21181 agcagaaggt tacgcagcaa aacattacaa atatttgcaa gtgaagactg tagacgaggg
    21241 gcactactct atatatgatc aaactatttg tttctacgaa tcattaggat tttcaaggtt
    21301 ggaagttttt ccaaatttat gggatgaatg gaacccatgt ttagttcttg tcaaaaaatt
    21361 ggaacaaaag tgagcaatag atttaatact aatctgtgct tgatgaaaat tctcactgta
    21421 aaaaatgctg aaaatcaagt ataataccat aggaacaaac tggaaggtga aaaagagcat
    21481 ggcacaacta ttttttaagt atggcgcaat gaatagcggc aagacgatcg agatcctaaa
    21541 agtcgcacat aattatgaag aacaaaataa gccagttgtc ttaatgacaa gcggtattga
    21601 tacaagagat ggtttaggcg ttgtttcaag ccgaatcgga ctgaaacgta atgcgatgcc
    21661 gatatttgaa gaaacagacg tatttgacgt aattcagaaa atggaaagca aaccctattg
    21721 tgtgctgatc gatgaagcgc aattcttaaa aaagaaacat gtcattgctt ttacgagaat
    21781 tgtggacgaa ttggatattc cggttatggc atttggtttg aaaaatgatt ttcgaaacga
    21841 gttatttgaa ggatcaaaat atttattgct ttatgcagac aaaatcgaag aaatgaaaac
    21901 aatctgttgg ttctgccaca aaaaagcaat catgaattta cattatattg atggaaaccc
    21961 tgtttatgaa ggcgatcaag tgcaaattgg cggaaatgaa gcttattacc ccgtttgtcg
    22021 aaaacattac tttcacccat caatgattac agaaggagaa taagcatgta cgatcaatta
    22081 caagcaattg aagaccgtta tgaagagctt ggagaacttt taagtgaccc agaagtgatt
    22141 tctgatacaa agcgttttat gcagctttca aaagaagaag caaacacgcg cgaaacagtc
    22201 gaagtttatc gtcgttataa agaagtagta caaggaatca ccgatacaga agaactgctt
    22261 ggtgaaaaac tggatgatga aatggctgaa ctagcaaaag aagaattatc tgaattaaaa
    22321 aaagaaaaag aagtcttaga agaaaaaatc aagatcttgc ttttaccaaa agatccaaat
    22381 gacgataaaa atatcatcat ggaaatccgt ggagcagcag gcggagacga agcagcatta
    22441 ttcgctggcg atcttttcaa tatgtaccaa aagtatgctg aagcacaagg ctggaaaaca
    22501 gaagtgatgg aagctaacgt taccggaatc ggtggatata aagaagtgat catgatgatc
    22561 accggagaca acgtatattc gaaattaaaa tatgaaagtg gtgcgcaccg cgtccagcgt
    22621 gttccttcaa ctgaatcgca agggcgtatc catacttcca ccgcaacagt tgtcgtgatg
    22681 ccagaagctg aagaagtaga gatcgatatt gaagacaaag atatccgtac agatatctat
    22741 catgcttcag gtgctggcgg acagcacgtc aataaaacag catctgctgt acgtttgact
    22801 cacttaccaa cagggatcgt tgttgctatg caagatgaac gttctcaaat caagaaccgt
    22861 gaaaaagcaa tgaaaatctt gcgtgctcgt gtgtacgata agatccagca agaagcacaa
    22921 agcgagtatg atgccaatcg aaaatcagca gtcggaactg gggatcgttc agaacggatc
    22981 cggacgtata atttcccgca aaatcgtgtg actgatcatc gtatcggatt aactatccaa
    23041 aaattagatc agattttagc agggaaatta gatgagatcg ttgatgcatt gatcatgtat
    23101 gatcaaacat caaaactgga agctatgcaa aatgggtaaa atgacctatc gagaagtcct
    23161 gtcacgggct tcttcttttt tagaggatca tgggaaagaa gcatatagta tccaattttt
    23221 atttttggaa cgaaaacaat ggaaaaaact tgattggctc cttcatatga acgaagagat
    23281 ttcagaagaa gaacagcggt tgatcgaaac cgatctgcga cttctgcttg cagatcatcc
    23341 acctcagtat ttgctaggat atgcagattt ttatgatcat cggttaaagg taactgaagc
    23401 aacactgatc cctcgaccag aaacagagga gttagtcgaa tggtgtttag acgagacgcc
    23461 tggtgtaccg ttagaagtga tagatattgg gacagggact ggagcaattg ctattagttt
    23521 gaaagcagca agaaaaaatt ggcatatatc tgctgtggat ctttcagaag aagcattaga
    23581 agtagcgaaa gaaaatgctc agaaagaagg aacgaaaatc agtttttatc atggagatac
    23641 attaggacca gtaatggatc agcaatttga tgtgattatt tctaatccgc cgtacatcag
    23701 tcggaatgaa tgggaactga tggatgaaag tgtccggtca ttcgaaccta aaatggccct
    23761 ttttgctgag aacgatggat tagctattta tgaaaaaata gcagttgaag caccaagcgt
    23821 actaaaatca aatggaaaga tttttttaga aatcggattt cgccaaggtg aagcagtaaa
    23881 aaaaatattt cagcaagcat ttccagataa aaaagtggcg ataaaaaagg atctttttgg
    23941 caatgaacga atgatccaag tttatggttg aagttgtgga tgaaaaattt tttatttgtt
    24001 tttttattat aaaaaaacac ttatttgaca aggatgtaaa cgactttttg gtttatcaac
    24061 aagtttatcc actattgaca aatagattat ccacaaacag tggaaaactt gaggataaac
    24121 tcagacaaaa taagaatgta tgaaaaaggg gttgtggata aactgtggaa acgaaacgat
    24181 atgatgaaac agaattgcaa gaggcagccg aagcactgaa agaaggagaa cttgttgctt
    24241 ttcctaccga aacagtatac ggattgggcg ccaacgctct tttaccaaac gctgtcaaga
    24301 aagtgttttc tgtaaaaggg agaccgcaag ataatccatt aatcgtccat gtcgcctctt
    24361 ttgaacaagt aaaagagtat gtggacaact ttcatccggc agcagagaag attgtgaaga
    24421 acttctggcc tggaccatta actttgatat ttaagatcaa aaaagacact ttgccctcag
    24481 ttgtgacggg aggattatcc acagctgcat ttcgtatacc ggataacaaa aaaacactag
    24541 aagtaatcga actttccggt gttccgcttg tcggtccaag tgcaaatacg tcgggaaaac
    24601 caagtccaac gactgcagat catgtatatc atgatctaca aggaaaaatt accgggatta
    24661 ttgatgatgg agctacgcga attggtgtag aatccactgt tcttgattta agtgatccaa
    24721 cagccatgcc tatgatttta cgaccaggtg cagtaacgaa agaacaaatc gaagcagtca
    24781 tcgaatctcc tgttgctatt gatcagcatc ttgtaaaaga aaatgaaaca ccaaaagccc
    24841 ctgggatgaa atacaaacac tactcacccg atacacgtgt tctgatggtc agagatggcg
    24901 attggtcaac tgcagttcaa tgggcaaaaa ataagaagat ccgtgcaggt gtcatagcaa
    24961 gccccgaaat tgcggatcaa gtgcggacag atactgcagc tgtttatatg tataacgaca
    25021 actcagtaga agcggcggct aaaggattgt ttgcaggtct aagaggatta gatgaaccaa
    25081 cacttggatt agatttgatt tttgtacaag tgtatccaga aactggattg gggaatgctt
    25141 acatgaatcg cttgaaaaaa gcagcaggac aaaattattt tgaaaaatga tcaattggtt
    25201 attgtcgcat tcttttagta tgatacaatg ctatcaagta aatcttctat cagtgaacga
    25261 aaaactaagc gtaactaatc gtaatagaag agatacgaat atttggcaat ttgtttttga
    25321 tgggaaaaat aaaattgtag gaaaataaaa ttgtaggaaa ataaaaagga gctgttgttt
    25381 gtggtagatt acaaaacgtt tgaccctgat ctttgggctg cgatcgccaa agaagaagaa
    25441 agacaagaac ataatttgga gctgattgcc tctgaaaact ttgtctccga agcagtgatg
    25501 gctgcacaag gaagtatctt gacaaataaa tacgcagaag gttatccagg gcatcgctat
    25561 tatggtgggt gtgaatttgt cgatatcgtt gaaaatttag cgattgaccg tgcaaaagaa
    25621 ttattcggag cgaaatttgc gaacgtccag cctcactccg gctctcaagc caacacggct
    25681 gcttatctcg ctttggtaga accaggggac acgatcttag gaatggatct ttccgcaggc
    25741 ggacatctaa cacatggatc accagtcaac ttcagtggca aaacctatca ctttgttgct
    25801 tacggtgttg atccgacaac agaagttatt gattataatg tggtacgtat tttagctaga
    25861 aaacatcaac caaaattgat cgtagcaggt gccagtgctt acggacgaac gatcgacttt
    25921 gcgaaattca gagaaatcgc agatgaagta ggcgcaaaac tgatggtaga tatggcacat
    25981 atcgcaggat tagtagcagc aggacttcat cctaatccag ttccttatgc agatatcaca
    26041 acgactacca ctcataaaac attgcatggc cctcgaggcg gcatgatttt gacaaacgat
    26101 gaagcattag caaaaaaaat aaatagtgcg gtatttcctg gtattcaagg cggccctcta
    26161 gagcatgtga ttgcgggtaa agcagtagca ttcaaagaag cattagatcc tgcatttaaa
    26221 gaatatagtg aacaaatcat cgccaatgca aaagcaatgg tcaaagtttt caatcaagca
    26281 attggaacca gagtcatttc aggggcgaca gataatcatc tgatgttgat cgatgttcgc
    26341 gagttaggta taaatggaaa agaagcagag agcattttgg acagtgtgaa tatcactgta
    26401 aataaaaact cgattccttt tgaaacacta agtccattca aaacaagcgg tattcgaatc
    26461 ggcacgccag caatcactac tcgcgggttc aaagaagaag atgctgtaaa agtggctgaa
    26521 ctagttgtca aagcattaca agcaaaagat gataacgctc aactagacga agtcaaaaca
    26581 ggtgtacgcg aattaactga aaaatttccg ttgcataaaa aataaaaatt taaattccat
    26641 tagtaaacag aaaagttcaa tgttgggctt ttctgtttat tttttgggaa aacggattct
    26701 ttgacaatat cggtgatgct ctctagtata tgaggtgtaa ttttagtctt cacactaaat
    26761 ctcagggagg aaaagtcatg actgatcgta tctcgttaga aaaggaagca gtagcattca
    26821 gtgatgcaaa tgcgcctcat ccgcgtatct atgaactagc accggaagaa ggaagagttt
    26881 tactagaaga agtacaagaa tcacctgtga acaaatattc cgtcgatatt gaagacttga
    26941 tggtggatac tggcgaatgg ggaaaactca atattcgtct cgtacgacca gaagggaata
    27001 tggataaatt accagttatt ttttatattc atggagcagg ctgggttttt ggcagtgctc
    27061 aaacccatga taaattgatc agagaacttg cggttcgtac gaattccgtc gttgtctttc
    27121 cagaatatag tcgatcacca gaagcaaaat atccaacagc aattgaacaa aattatgctg
    27181 tgttgcaaca gctgaataaa ttagccaagt caaaaaatct ggatctcgag aatctaatcg
    27241 ttgcaggaga ttcagtaggt ggtaacatgg ctacagtcat gacgatctta acaaaagaac
    27301 gaaagggcct cccaatatcc aagcaattgc tgtattatcc agtcacaaac gctgattttg
    27361 atacagattc ctatcatgaa ttcggagaaa actatttttt gacaagagaa ggaatgatgt
    27421 ggttttggga ccaatatacg acgaatgaag aagagcgtgc tgaaatcaca gcttcgcctt
    27481 tgagagcaaa tataaatgaa ctaaatgatc ttccttcagc aatgatttta acgggagaag
    27541 cggatgtatt aagagatgaa ggtgaggctt atgcgcgcaa acttcgtgat gcaggggttc
    27601 ctgttacaca agtacgcttc caaggaatca tccatgattt tgtcatggta aatgctatgg
    27661 atcagacaaa ggcaacgcgt gcagcaatgg cattatctac ttcttggatc aagaaaaaag
    27721 aataagcttt gcttgtccgc aggaaaactt cttttcaaaa acggattttc ttaggaaaaa
    27781 tggcgagttt gactagtcaa tcacttgatt ttgttttaca attaaaaaga aacgacagaa
    27841 caaaggagag cttaaaaaat gggcaaattt caagtgatcg atcatccatt gattcaacac
    27901 aaactaacta ttattcggga caaaaactgc ggaacaaagg tttttcgtga agtagtcgat
    27961 gaaatcgcta tgttgatggc atatgaagta tcacgggata tgccattgga agacatcgtg
    28021 atcgaaacac cgatcactga aacaacacaa aaaacgttgt ctggtaaaaa agtagcgatt
    28081 attccaatct tgcgcgcagg tattggaatg gttgacggta tcttggaatt gattccagct
    28141 gctaaagtgg gacatatcgg tctttatcga gatgaagaaa cattggaacc acatgaatat
    28201 ttcgtcaaac ttccagaaga cattgatgca cgtcagttgt ttgtagtaga tccaatgttg
    28261 gcaacaggcg gatcagcaat catggcaatc gatgcattga aagaacgtgg cgcgtcgaac
    28321 attaaatttg tttgtttggt agcagcacct gagggagtaa aagctttgca agaagcgcat
    28381 cctgatattg acatctatac agcttctcta gatgaaaaat tgaatgaaca tggttatatc
    28441 gttcctggac taggggatgc gggtgaccgt ttgtttggta caaaataagt aaatacgaaa
    28501 aagggtgtga cacaactttt gtcacatcct tttttggtca tttttaacgt ttgatgcaga
    28561 acagcttttt cacagctttc gtttgcatat aaaaaaacca tcccaaaaat gcagagatgg
    28621 tcaaattcaa atctttttta gttctttgta gttaacgatt actacaccct tactttgcgt
    28681 catcaagttc gcattttctg cagtttcatc aatctcaaca acagcggaat ttttcaattg
    28741 ctttgaaatc gttccagttt gcgacttgcc gtgaattgtg aacattacgt gagtattgat
    28801 cttgaatttt tcaccaattt ccgatggtac gatagttgta tcaaattttc caaaagttgc
    28861 cattttcata aaacctgtct ttcacatcaa ttataccacg ttttatgaaa aatatcatga
    28921 aattaaacta attttccatc ggactcttta caatcagcca aatagagtat ataatttctt
    28981 ttggataagg ccagcttagc tcagttggta gagcaacgca ctcgtaacgc gtaggtcgta
    29041 ggttcgatcc ctatagctgg cattaaaaga gaagacagat atatcaagga tttttaatcc
    29101 attgatacat ctgtcttttt gtttaaagga aataaagtat gctttcttag caatagagca
    29161 tgtattattt ctataaaaat ttaggagaat aaaacgacta gcaatatagc tgtgaaatca
    29221 aatatcacat gaactgccca acttgtaatg atcgagttgc ttttaatggc agcttggttg
    29281 aataacaatc ttgccacccc ttgtatcaaa aggatgtgtg ctacagtgtg taaaatattt
    29341 ccattatcat aagtactgta atggataaat ccaaagatga ttgctgacaa gaaactagcg
    29401 acaggaatgc tgaacttact agaaaaaata gcgagaaaat acactgagaa caattcttct
    29461 ccaagtatca tgataggcaa aataataaat aataacgggc tgaaagcctc atttattgga
    29521 ttgcctgtta aaccccattt caaaatttgt tgcaaaaata ccgagactgc ggcactgatt
    29581 actacattga taaaaaaata tttggctata tttttgacag gagcgacagg tttcgagaac
    29641 atttttttcg tatctttttt accaaaaaca agtgtaaatg ctataaatcc agtgatagtt
    29701 aaagaaaaaa tgctaataat ggatggcgca aatagcaacc ctaacaaacc gagtacaacg
    29761 acaatagtgc ccaatatccc ttttttaagt tctatttttt ttcctaaaat gttattcatg
    29821 ataataactc ctactattca gtttttgaag atagagtcag tatacatgaa gagttaaaat
    29881 aggcaatgtt tttttatgga tatttgtatt gctaaaaatt tatcttatat attcattttg
    29941 attatactac ttttatttgt aaaaattttc tagcaaaacc aagtgcttgc aactgattaa
    30001 gcgtacaatt ttttagatgt tccgagcgta cttcaatcat ttcaaaggag ttgctactta
    30061 aatcgatatt ttttaaatca gtatcaaaaa agctagcatt ttctaaatca ttagtagaaa
    30121 acattatttt agtgagggaa cagtctacaa aatctgcgct tgataagaca gagtgctcaa
    30181 aggtactttc ttttatgttt gaaccagata aatttacata gtccatttta caattctcga
    30241 ataacgtgtt cccaatataa ctttccatca atttagtacc tgttaattta caattgacaa
    30301 atttcacgcg atgcaacatg ctttttgtca atatacagcc tgaaaaatca cagttttcga
    30361 atatacagtc ggtaatctcc attctttgaa aatcattgga agcaaaaaat gcatacttga
    30421 aaatagattt gtaaataatt ggatggcaga ttatttggtt ttcgatgacc tctttttgtg
    30481 aaaggatatt atacagttca aaatcttcgt tttcatagat atgaaaaaag gatcctttat
    30541 tcaagcttgc ttcattaact ttaggaaaaa tcatatttaa ttacctccat tttcataaag
    30601 tcatattaac aaaagctaaa ccaacttaca ttagcagaaa atgagatagg ttttcgcctt
    30661 tttcgataac gatagtgtcg ctatctcttg aaacgttctt agaattgccc tgagagacac
    30721 aaattaggcg taattctaat aaaaatctta gaataaaaat ttttactgat ttaatttaga
    30781 atgtttttaa aataaaaatc gttgccataa cagtgtattg aaaggtttta acaatccagt
    30841 aatgatttaa aaaaatctag atgtagcgta tactttgttt atagaatgta gtgggaagaa
    30901 atatattttt gggaggaaat cgtgatgtct aaaagtgaag aaatagaaaa catggtacta
    30961 aaattatatg atctcgtttt aaatccagag atcaaagaaa aggaacgtat acttttgata
    31021 gacgcaaaga caggcttaga aaaaggtcag tattatccta aagtcataaa taatttggaa
    31081 cgtagtttac gtccgttagc aatcagggga gaattgtcta aaccagtatc accgttttat
    31141 atggagatat caacaatagg aaaatttgaa aaagaattag gtcgaggaat ggcttcggca
    31201 ccgattactt ttgggcattt ataaaaacga gttattcatc tcaatgaatt aaaaagtata
    31261 gtcaatctca taatgcaggc taggttcatt tatttgaaca gagtctgtat ttttttattc
    31321 taaataaaga aacagatgtt tctttatatt gtattttatc ctttaattaa cacaaaaaca
    31381 gctagtataa actaataatg ttaattaaaa gtgtatttta tgaaactatc gttatttatt
    31441 aatgttgcat ttttgtaagt taaaaattgg aaatatagat tgaaaaaatg aaagcaataa
    31501 gta
//
LOCUS       DAIGWC010000031        29228 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.031, whole genome shotgun sequence.
ACCESSION   DAIGWC010000031 DAIGWC010000000
VERSION     DAIGWC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29228
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.031"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..170)
                     /locus_tag="NOB74_001400"
     CDS             complement(<1..170)
                     /locus_tag="NOB74_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220594.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLS"
     gene            complement(261..713)
                     /locus_tag="NOB74_001401"
     CDS             complement(261..713)
                     /locus_tag="NOB74_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCI1220595.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(726..1136)
                     /locus_tag="NOB74_001402"
     CDS             complement(726..1136)
                     /locus_tag="NOB74_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1220596.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1411..1623
                     /locus_tag="NOB74_001403"
     CDS             1411..1623
                     /locus_tag="NOB74_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1220597.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1626..1838
                     /locus_tag="NOB74_001404"
     CDS             1626..1838
                     /locus_tag="NOB74_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220598.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            1978..2133
                     /locus_tag="NOB74_001405"
     CDS             1978..2133
                     /locus_tag="NOB74_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220599.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(2130..2354)
                     /locus_tag="NOB74_001406"
     CDS             complement(2130..2354)
                     /locus_tag="NOB74_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HCI1220600.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2432..2620
                     /locus_tag="NOB74_001407"
     CDS             2432..2620
                     /locus_tag="NOB74_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220601.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2946..3281
                     /locus_tag="NOB74_001408"
     CDS             2946..3281
                     /locus_tag="NOB74_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220602.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3514..4455
                     /locus_tag="NOB74_001409"
     CDS             3514..4455
                     /locus_tag="NOB74_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HCI1220603.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4457..5347
                     /locus_tag="NOB74_001410"
     CDS             4457..5347
                     /locus_tag="NOB74_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HCI1220604.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5390..6190
                     /locus_tag="NOB74_001411"
     CDS             5390..6190
                     /locus_tag="NOB74_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI1220605.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6205..7056
                     /locus_tag="NOB74_001412"
     CDS             6205..7056
                     /locus_tag="NOB74_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI1220606.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7257..7718
                     /locus_tag="NOB74_001413"
     CDS             7257..7718
                     /locus_tag="NOB74_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1220607.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7744..8196
                     /locus_tag="NOB74_001414"
     CDS             7744..8196
                     /locus_tag="NOB74_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220608.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8302..8496
                     /locus_tag="NOB74_001415"
     CDS             8302..8496
                     /locus_tag="NOB74_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220609.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8527..8820
                     /locus_tag="NOB74_001416"
     CDS             8527..8820
                     /locus_tag="NOB74_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220610.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            8850..9290
                     /locus_tag="NOB74_001417"
     CDS             8850..9290
                     /locus_tag="NOB74_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1220611.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            9365..9832
                     /locus_tag="NOB74_001418"
     CDS             9365..9832
                     /locus_tag="NOB74_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HCI1220612.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            10579..10809
                     /locus_tag="NOB74_001419"
     CDS             10579..10809
                     /locus_tag="NOB74_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220613.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            10968..11801
                     /locus_tag="NOB74_001420"
     CDS             10968..11801
                     /locus_tag="NOB74_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HCI1220614.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11794..13209
                     /locus_tag="NOB74_001421"
     CDS             11794..13209
                     /locus_tag="NOB74_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI1220615.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13221..14750
                     /locus_tag="NOB74_001422"
     CDS             13221..14750
                     /locus_tag="NOB74_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI1220616.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14668..15720
                     /locus_tag="NOB74_001423"
     CDS             14668..15720
                     /locus_tag="NOB74_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HCI1220617.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15722..16039
                     /locus_tag="NOB74_001424"
     CDS             15722..16039
                     /locus_tag="NOB74_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220618.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16166..16789
                     /locus_tag="NOB74_001425"
     CDS             16166..16789
                     /locus_tag="NOB74_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HCI1220619.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16804..17694
                     /locus_tag="NOB74_001426"
     CDS             16804..17694
                     /locus_tag="NOB74_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HCI1220620.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17717..17932
                     /locus_tag="NOB74_001427"
     CDS             17717..17932
                     /locus_tag="NOB74_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220621.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            17944..18285
                     /locus_tag="NOB74_001428"
     CDS             17944..18285
                     /locus_tag="NOB74_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220622.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18285..18656
                     /locus_tag="NOB74_001429"
     CDS             18285..18656
                     /locus_tag="NOB74_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220623.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18649..19044
                     /locus_tag="NOB74_001430"
     CDS             18649..19044
                     /locus_tag="NOB74_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HCI1220624.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            19046..19423
                     /locus_tag="NOB74_001431"
     CDS             19046..19423
                     /locus_tag="NOB74_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220625.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19424..20032
                     /locus_tag="NOB74_001432"
     CDS             19424..20032
                     /locus_tag="NOB74_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI1220626.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            20032..20373
                     /locus_tag="NOB74_001433"
     CDS             20032..20373
                     /locus_tag="NOB74_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220627.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20615..23404
                     /locus_tag="NOB74_001434"
     CDS             20615..23404
                     /locus_tag="NOB74_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HCI1220628.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AFFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            23394..24134
                     /locus_tag="NOB74_001435"
     CDS             23394..24134
                     /locus_tag="NOB74_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI1220629.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            24131..26893
                     /locus_tag="NOB74_001436"
     CDS             24131..26893
                     /locus_tag="NOB74_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI1220630.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            26906..27814
                     /locus_tag="NOB74_001437"
     CDS             26906..27814
                     /locus_tag="NOB74_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HCI1220631.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            27814..28434
                     /locus_tag="NOB74_001438"
     CDS             27814..28434
                     /locus_tag="NOB74_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220632.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            28438..28887
                     /locus_tag="NOB74_001439"
     CDS             28438..28887
                     /locus_tag="NOB74_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220633.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
     gene            28887..>29228
                     /locus_tag="NOB74_001440"
     CDS             28887..>29228
                     /locus_tag="NOB74_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220634.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYR"
BASE COUNT        10482 a         4214 c         6036 g         8496 t
ORIGIN      
        1 tctgatagtg tttcttcctt acttaatata aatctttctc tatcatgtaa tttatttagt
       61 ttttcatcat ttttttgttc taattcataa gcttcttttt ttattgtgtt agctttcgac
      121 agtttagtga ttcctataat taataaaata agtccaatca ataataacat tcaaaactcc
      181 tcatttcttt gatataatta ttgtagagtt tactcagaaa tgaggaaaga gtccatgtga
      241 aagcatgggc ttttttattt ttaatgttgt aatactaaat gttcaagatt atgaggaagc
      301 cctaaatatt caataatttg gaactgactc atatcagata aatcttgttc atctattgtt
      361 ctagttaaca tttcaattgc aaacatatta gcttcagctt ctataccata aatcatacaa
      421 ctaaggttgt ttgctctaaa agctgctgtg caaatacctt tatggagtct aacgtgggct
      481 atttcatgcc ataatacaaa tcttttcata gaaggtgata ggttttgatt aattaatatc
      541 acataacatc ttttattgtg tatcgtttgt cctaatgttt tattccctaa atcagtttca
      601 attaaatcta tatcagaata tttgattatt ttatatggat taatcgcatc agatccaaac
      661 tctacaaata atttttctat ttcttctaat atccagtatt tgtttaaatg cataccaaag
      721 cccacctatt gacgatattt tttaggagtg aattttttct ttgctttaac tttggttaag
      781 gcaagtgcaa gttgaatggc atcgtataat ttttccttat cttcatcgtc taaaggttca
      841 ccataataat ttgtttcagc atctgaattc aagccttcaa gtaatttttc agcttgtaaa
      901 gcaatatctt gtttatcttt ttctgttaaa tcataataat ggcgtttatc agtacgtcct
      961 aaaagataat cagttgatac attaaagtaa tctgcaactt tttgtatttt atctccagat
     1021 ggagtacttt tattccatct agacatgctt ccatttccga aatttaactt tctttcaagt
     1081 tctgccaacg tcattgaacg ttcttttaat aagattttta tacggtctaa tagcatagga
     1141 tatgcattcc tttcaaaata ccgacaaaaa aagtattttt ctgcaaatta tctatttaca
     1201 aatagagaat ttgcagttat actagttttg taagcaagat atttacggca tacaaagact
     1261 aaaagcaata aactaatagt ctccccagac atcagtaagc tcgctttttg tgcgctgtat
     1321 tttgtatgct tacataatag catatttgca gtttttgtca aacttattag acaaaaatat
     1381 tagaaaatat tcgataaggg ggtatgaagc atgactttaa aacagcaagt attaattgct
     1441 ttagtaaaga aaggttggag tcaaagagag ttagctcgac gaatgggtat atcaattact
     1501 tatttacgag atatcttcat cgaaaaaaga aaacctaagg aacgtttaaa acaaatcgaa
     1561 gaacttttgg atatcaagtt agaagtagat tctaatgatc agccatcaga acaggaggcg
     1621 taaaaatggt acaacgtttg agcaaagcgg agtttaaaga gaaatataag tattctgaaa
     1681 gtacttatca aagaagaatg aaggaattta aaaaatcacg ttttagtgag gggtataacg
     1741 cagttacttc caaagaaata acaattgatg tcgatttata tgaacagttt agaacatggc
     1801 gttctaaaaa tcgatttaga gttagagctg tttgttaata gctaaaaaat ctaaattcac
     1861 cacttctgaa aagaggagtt gctgctctcc tttcaagttt gccaaagtcc acgttttttc
     1921 attttggcaa ctcctcttct tggaggtggt gacggcgaga gacgaaggag ggatgacatg
     1981 aaggaagaat caaaaatagg gattttgaat gagaacaatt acacaagatt aattattgaa
     2041 acagaagaag ggaaaaaagt agcagaagtt acattgaccg atgcaactcc tgctgacggt
     2101 tatcgtattc gattaactcc taaatatgat taaccttttg gtgggtgtgg atcgtttccg
     2161 tgactatcac ggctttgaat ttttccatct ctgccatgaa taaatagctc agatccttga
     2221 tttttagaaa tctctctagc gatttttact gcttctgatt ttgtattagt atgtgcagtc
     2281 gctttagaat ttccagcacc tttgacattc caaccaccat tggaattagg tacaacatgt
     2341 tgattttttc ccatagtttt cacctccatt tctatagaaa tattttatca aatagaaatg
     2401 gagaaattca ataaacgaaa ggagaagtga tatggcatat accttgcaac aagaacatca
     2461 aattctcggt ttgattaaac aacgcaggaa acaattacaa gatgaccgtg cagcgcttag
     2521 aaaagccgat gagctatcag ataggcaagc tgaactaatt gcttctgaac ttgaggattt
     2581 gagaatgcta gaaataaaaa atagggagat tagattatga agaagacaga cacacttttt
     2641 ataggattca ttttggggtt attagtgatt gtagcgcacc aaagtattat cgggggaagc
     2701 ttgttcgcag cattgatggt tttaatcaat ctgcttgatt caaaagaaag gagcaactat
     2761 ggcacgagaa gaagcgctaa aaatcggtaa agtgattgct gataatcggt ggggaaatag
     2821 ccgccctatt attttaagca agcaacatat cgaaaagcaa aaagcatggc aacaaataaa
     2881 aaagtgactc tgccagccag caaagagtca catacaaatt tataaaacta ggagaattat
     2941 atcacatgaa taagaaaatt gaaaatctta tcgaagaatt gaaacgtgaa tgccaaaagc
     3001 aaggtgtttc tattatttgt acagcccaaa aagaagggga acttaaaagt ctcgtttatg
     3061 gtgagacaac agaaatttta ctttgtcttg ctatgcaaga agaacattta gatgaaaatc
     3121 tcccattgtc agcacatatt atgcgtagaa ttgctgtgga tgcttacgaa caagcgaaaa
     3181 atgaagaaga aaatcaacct tcaaatcata cttttgttat taataacaag gaagatttag
     3241 ctgatgtgat gactcgtatt ctcaaggggg aatttcaatg atgaatgaaa aaacaattga
     3301 tctactcatt attttatttt tcacgttagt gattgtagcg aaaagttatg taatctttgg
     3361 cttgttattc gcaattacca tgcttgtgct ttgcgtgtta gcaagcagaa aagaggttaa
     3421 acatgaacga gttagcaaat cttgacaact atttaactga tcctgattat gctaaaccac
     3481 catatgaagc accaattgat gaggaggatg aagatgagta aatctacctt agaaatgagc
     3541 catcaagaat ggcttgaaga ccgtaagaaa ggcatcggag gttcggatgt tggaacaatt
     3601 ttaggattga ataaatggaa atctccttat caactatggc tagaaaaaac aggacaagta
     3661 gtacttgaag aatcaggaag tgagcccgct tattggggta atgttttaga agaagtggtt
     3721 gctaaagagt ttcaggaacg tacaggcaaa aaagtacgca gaagaaacca agtatttgaa
     3781 catccattac atccattttt aagagcaaat attgatcggg aagtagtggg agaaaatgcc
     3841 attctggaat gcaaaacagc caatcaattt ctcggtaaag aatgggaagg cgaagaggta
     3901 ccgcttagct atctctgtca agttcaacat tacatgaacg ttctaaacaa agactattgt
     3961 tacatcgctg tcttaatcgg tggtcaaaaa tttatctgga agcggattga acgagatcaa
     4021 gagctgatcg atacaatcac tgaacaatta gtagagtttt gggaaacaaa cgttcttgga
     4081 ggtatcgagc caattattga tggtagtcaa gcgacagctg atttcttgaa agagaagtat
     4141 gcagatgttg aagacgttca aacgacgtta ccaattcatt tcgatgaact agttgaacag
     4201 aaaaacgaac tcaaacggac taagaaagaa attgaatcag ctatccgtca agtagacaac
     4261 gagattatca gcgagctagg taaacgtgaa gccagtatcg gtatcactca aaaaaacatc
     4321 atcagttgga aatttgtccg tacgagacgt atgaactcga agaaactagc agagaaatat
     4381 ccagatgtcg caaatgatga agagatttat aacgttactg aatcaagaag gctaaccgaa
     4441 agggagatca aataatatgg caacaaatga atcgttaaaa aatcaattgg cagcaaagcc
     4501 acagaaacaa gttgcaccag gtcaattagg acttaaagct ttgatgaata caccaacaat
     4561 gagaaagaag ttcgaagagg tgcttcatga caatgctaat gcttttatgt cgaatgttat
     4621 gactcttgta tctaatgaca gttatcttgc agatagtgaa ccgatgtcta tcatgagtgg
     4681 tgcgttaact gctgcaacat taaatcttgg gctagataag aatttaggtt atgcatattt
     4741 agttccattc aatagtaaaa acaagcaaac aggaaaatgg gaaaagaaag ctcaattcat
     4801 gcttggctat aaaggatata tccaattagc ccaacgatca ggtaaataca aagcattaaa
     4861 tgtgatcgaa gtttacgaag gagaactaaa aagctggaac cgactgacag aagagtttga
     4921 gtttgatcca aatggtagaa cgtctgatga agtcattgga tatgttggct atttcgagtt
     4981 actgaatgga ttcaaaaaaa ctgtctattg gaccaaacaa gaaatcgaag ctcatcggat
     5041 tgctaacaat aaagatcgcg ataagacaaa gttaagtggt gtgtgggcat ctgattacaa
     5101 tgcaatggca cgaaaaactg ttttgagaaa tcttctttct aaatggggaa tcttgtccat
     5161 cgaaatgcaa gaagccacca catcggatga gagagtccaa agggttcaag aagacggcag
     5221 cattattgct gaaacagaag ttgaagaaga tattcctgaa agaaaagaag cagaggttat
     5281 atctgaagaa aatgaagatg tacaaactgg attatttgat gcatctaatc cgccgttaaa
     5341 caaataatga gggagctttc tcccttgctt ttctagagga gaaatacgaa tgaacacagg
     5401 atatgtcaaa ttacatcgaa aagtgatgaa ttcattcgtt tggaccaatc cttatatgta
     5461 taaattatgg aacttgtgtt tgatgaaagc gagtcatgag aatcgcaaga tactttttaa
     5521 tggaaaagag atacaagtga acagcggaga attcgtcaca gggcgcgatg ctatcacatc
     5581 tgagatgaac gaaggcgtga aacgtgaaca tcaagtgaac agcggttctg tatggagatg
     5641 gctaaaacaa tttgaaaaaa acggaatgtt gaacatcaaa tcaactacga aatacagcgt
     5701 tatatcaata aaaaactggt ctttgtacca aagcagtgaa caacaaatga acatcaaacg
     5761 cacaacaagt gaacaacaag tgcacacaaa caagaatgaa aagaattata agaatgaaaa
     5821 gaataataaa acatcatcgt cgcaaccacg caaaaagcgt gtttacgaca ccgactcagt
     5881 ttactacatt ctcgcggagg agttattcaa acagatttgt cagaatcagg aaatcaaaaa
     5941 gccgaatctg caaagttggg cagatgacat tcggaaaatg atcgagatcg acaagcggac
     6001 cgaaaaccag gtacggggaa tgattgaatg gagtcagcac aatgtgtttt gggcatcgaa
     6061 tattttatct gctaaaaaat tgcgagaaaa atacgacaca atggcagcgc aagcaaatcg
     6121 tgattataaa acaaaacaaa ctaaaacgct tgaatacgag aaatttagca cagatgagtt
     6181 gcctatttga gaggaggcgt aggcatggaa actgttgggg aaatcatgga aaagctgata
     6241 cagaaagtgc ttgtccaacg tggcgaatgt cctgaatgcg gacagccttt gtatggatgg
     6301 cgtacgaaga accctgatgg ctcagaacgt tgtaagccaa cctgtatgca atgtgggtat
     6361 aaagcattgc gagttcagga agacttacaa acagaacgaa tttacaacga gagcctgaaa
     6421 gcaagagcaa tcaatttttt caaaggtggt tctgttgtgc ctaatcaagc gttgtttgat
     6481 tgcacattgc agaattatca aattgtcgat caagaaacaa gacaagcggt tgaagtaacc
     6541 aaacgctttg ttaattcagt cttgttagga aatccaagtc accttgtttt aactggaaaa
     6601 caaggaacag gtaaaagtca cctagcgatg gcagcggctt gggaagtctt gaagcgatca
     6661 aactacgata aaaaaatctt atttatcggg ttacaggaaa tgctggatca aatcaaattt
     6721 tcgtacaaca atcctgaact cagaaaaacg attgagggat cgttgattgc agatatcaaa
     6781 acagcggatt tagtcatcat tgatgatatc ggttcagaac taggaaaaga tgcatcagat
     6841 agtcgagcgt ttggcataaa cacgctaaat tcgttcttgg atgcacgaca gaacctagca
     6901 acgattatca caacgaactt gcttggtgaa gaactgaaaa aagcttacgg tacgagaaca
     6961 atatcaagaa tgtttgtcaa ctctgatgga tttacgatgg tattttctca aacagcagac
     7021 aagcgcataa aaccagtcaa aggagcgatc gcatgaattt gactaaacaa gaaaaaagaa
     7081 tctgtcgtca gataatgttg caaattatag gtgatcgtga catggacgaa ttatctcaac
     7141 aagagagtcg aatggttcgg aagataagta agctaattat ttatcgggat acagaaagat
     7201 ttctcactgt tttaggtaac gtctacgaga atccagagtt attggaggta gagtaattgc
     7261 caaaaatatt agatgcatgt tgcggtagta gattgttctg gtttgataag aacaattctg
     7321 acgtaacatt tatggattgt cgtcagcagt atgaagaatt atcaacaggt catgtgatca
     7381 atgttgatcc agatgtggtc gcagactttc gcgatatgcc ttttgaagat gatgtgttcg
     7441 atatggttgt atttgacccg ccacacttaa gacatgtcgg cgaaaactca tggcttgcca
     7501 aaaaatatgg aaaattagac gaactttggc cagaagacat caggcaaggt tttgcagagt
     7561 gtatgcgagt tttacgacct tcaggaacat taatttttaa gtggaacgag gaacagatac
     7621 cactttctga tgtgttagag gctattggag aacagccatt gtttggtaat aaacgaagca
     7681 aaacacattg gcttgtgttt atgaaaaaat tcagctaacg gaggaaacaa aggaggaaaa
     7741 gtaatgaaga ttgtattaaa taaatgtttt ggtggctttg ggttgagcca tgaagcaaaa
     7801 atggaaattt ttaaaagaaa aaatattgaa gtattcccat acatcaataa ctttagctat
     7861 gactcagatg atgaatacac gagatacaca ggccaaaagc taggttcgat ggattttatc
     7921 tactatttca aaaaagaccc gaaaatcgac aaagttacag gaatttatag cgaaattgac
     7981 cgactgtacg gaattgctga tgattccagt ttttcaagtg attcaaacag aggtgataag
     8041 gacctcgttg ctgttgtcga aaaactagga agtgaggcca gtggaccata tgcaagtctt
     8101 aaagtcgttg atatacccga tggggctgag tgggaaataa gtgattatga cggcgttgaa
     8161 actgcacatt atggttttca aacaggtagt atttagtcca ctaatgacaa ctaaagagga
     8221 ggcagaagga tgagtgaaga tgaatacttt gaacagtagt ctattaacga cagagatttt
     8281 taactggaaa ggggtgtagt catggacgca tcggaagtag taaataaaat taatagtctc
     8341 aaagaggttt tcggagacgt cgaagtagtg ataaacgcac aaggctatga caacgaattt
     8401 tttaagcaga ttaccgacat tagcattcag caaggaatgg aagacgaaga cggaaacttt
     8461 atcgatgaag tagccatttt agtgacttgc gagtaagtaa ttgacagcta aagaggagga
     8521 agcggaatga aactaaaaga cggattttac tccagcggcc acggcatcgg cggtttaatg
     8581 ctagatatgc cgacaaagaa tcctaaaaca cgtaagaaac caaaattcaa agtcggtgac
     8641 atggttcgct gcgaagcaga aggattcatc tatccatttc gtggatatgt agaacacgtc
     8701 tataatcact cagcaatcat tcgcattgaa aacacgatgg aatgtgataa gtggttagcg
     8761 aaaagcaaag agaatttagc agtggtgaga ttggtggaca tggaagttat aaaatcttaa
     8821 ttttgctttt ttacaactat cctacaacaa tgagcgttat tccacaactg gaaggagaag
     8881 aggcaattgt gaacatttta gagaatatag atattaagca aacaaggaaa aatgctagac
     8941 gattactaaa aagatacaga aatttagaac gtttggtcgg accagtgaaa atagactttt
     9001 ccgtgatgac tgttaccaaa aatttgaaat tcacaattga cagtcaaaac gaagaaatca
     9061 ttgaagcgat aagtactcga gattcggtta tcgaagcatt aacacggcta agtagaatcc
     9121 atttccaggt actttattat agttattgtt ttcctaataa gatgtcaatg tatcaaatag
     9181 gagaaaaatt aggatattcc gatagaacta tcgagagaat gaaggcagta gctttggttg
     9241 aatttgctga ggcgtataaa tcaggagaac tcatttcacg tacaaaataa aaaaagtcgg
     9301 attcctccga ctatgaataa tatttccgac ataagtatta tatcataatt gggggaatca
     9361 gaggatggta cttttcgatg taaagaaata tgagacacca agcgcgaaag atgttgatat
     9421 ggaacgcaca aaacataatg tcgctgtgtt tctttcagca tatctatcag ctagatgtag
     9481 agtagggcaa catcgagaac caaaagtgac agcatcttat tccttggttc caccttctac
     9541 agctgatcat atatttgaag cagaaagaat gctgatcgat aaagaagaag cacaggaaga
     9601 atttgagtat ctgcataaat tgtttgttcg aggctattca gcgatacagc atccgcataa
     9661 gcctgatgtg actgaaaggc gcaagaagat attctatgat cgttatatca atggtctgcc
     9721 catttatgta actgctcaaa ggaataatac tagcgaagaa tcggttaaag tagaatcaaa
     9781 cagaattatc atccaatttg cttcatcgtt agaactggtt gctttcaagt agccagtttt
     9841 tacacttttt ataccctttt attaccaatt tggtttccat tttatacctt ttttatacca
     9901 atcacttacc tattcaacgt tgtattatga tagtgtcgaa aaattaggaa acaggatcga
     9961 caaaataaaa tgtaagggag gaaatctccc tcatcgttta attaagcttc gataggcagc
    10021 aacggaaata ttaagaataa ggatgtgaat ttcaactcct tctaaattgt tcttattatc
    10081 tatcatccgt tgctgtctat tgttttttta attattcaca cgataactaa aggtaagtga
    10141 agagaaatga ttccattaat aatttcaatt tttgcgcttt gtcttaatgt atatatgatt
    10201 ggatttaaaa atgggcaaaa taaaaaatag tagcagccaa gaataatttt atagtgtcac
    10261 tgtggcggaa agggtagacg ctaagcatgt gtgctaggtc aatgcttcgg caaccatgca
    10321 aggttcgatt ccttgccagt gactttggca accgaggcat cggcggttta aaaatatagg
    10381 ggtgcgcaat ttcgtacgcg ttttgtgcat cgtgtaggtt gctattacat aactggttag
    10441 gttagattga gatttgggat tcggtacaaa tgaatcgtca aatgtctcaa gcacaggatc
    10501 ggaaacgtcc ctgcctgtgc attacatatt agatcactct ttgagtggtc tttttcttta
    10561 cataaaggag gctacataat gagaaactac tggtatgtat cgctaactaa tgaatatcct
    10621 cgaaccattg atgattgttc agtgcgtgtt gtgcgttctg tacaaatcaa agggaagtac
    10681 tctattgtcg aaatggggag agaagcagaa ccatgtgaga ttgatgcgtg caagctcgtt
    10741 tattgcggtc atggtttcta tgatgaacca aacattcaaa ataatattaa caagaatttg
    10801 agggattaga atgcaagaaa tggcttaaaa atctccaatc aggacaaatc aagttagaca
    10861 aagtttccga tttaaagata ttgattgaag ctgatttaat gctaaaagat attgaaaatt
    10921 agaaaacaaa actcaaccta aacagaatgt gaggtggtgt gtattgaatg gcaagacaac
    10981 gtgatccaag acgtgatgaa gccaaaagaa tttggttaga atccaacgga gaaaagcagt
    11041 taaaggaaat tgcatctgaa ttaaatgttt cagattctca ggttagaaaa tggaaatcgc
    11101 aagacaaatg gagcgctgaa ttgattagta acgttaccaa tggcaaaagt aacgttacta
    11161 atcaaggtgg cgctcctatt ggtaatcaaa atgctaaagg taacaaagga aatagccgag
    11221 cttctccgcc agtgggtaat aaaaacgctt tgaaaacagg tgagtatgaa acaatatttt
    11281 ttgacacgtt aaccgataat gagaaggaca tctattctag tttgaatgat gatccttctt
    11341 ttgctttgtc cgaagaaata cgacttctta aaataagaca acttcgaatg atgaaaagaa
    11401 tccaacaagc tgaagctgga ctaaatgatg aagaagtcga acgattgcag cagctaagaa
    11461 agattaaaac tccgattgaa aaaaatggta aaaagctaga aatcaagcgt gaggttatgc
    11521 aagatgtgca gattagcaga aaaaaacatc gcaaaattga tgatattctt tcaattgaag
    11581 attcattgac tcggattagc aaccagttag ctaaagccat caagcaaatg aatgaacttt
    11641 atatgaatga atacagaact gatttaatta aagctcagac tgataagatc caagctgaga
    11701 caaatgaaat tggcggaaat aattcaggtg aagaaataga agaatggaaa caggcagttt
    11761 taaatgccgc aaacaaacgg gcggtgaaag aaaatgaata atgaatttat tccttttgct
    11821 gatattggtt ctgccattga ttattactat gataaaccag tagctttttg ccaagatatt
    11881 ttgcatttga atcctgatga atggcaagaa aatgttttaa atgatttagc tgaattttca
    11941 aaggtttctg ttcgttctgg tcaaggagtt ggaaaaacag cattagaagc aggagcaata
    12001 ctttggttct taacgtgtcg accctacgct aaagtaatag caacagctcc gacaatgaag
    12061 caactttacg atgtactttg ggcagaggta gctaaatggt taaatgatag cttgatcaaa
    12121 aacttactga agtggacaaa gaccaaaatt tatatggttg gtgattcaga gcgttggttt
    12181 gctacggcta gaacagcgac taaaccagaa agtatgcaag gttttcacga ggaccatatg
    12241 ttgattgtgg tagatgaagc ttctggtgtg tctgatccaa ttatggaagc tattcttggt
    12301 acgctatcag gttttgataa taagctgttg atgtgtggaa accccaataa tattgaaggt
    12361 gtcttttatg attcccataa ttcagaccgt gataaataca gagttcataa agtatcaagc
    12421 tatgatagta aacgtacaaa caaagacaat atagaaatga ttcttaaaaa atatggaaaa
    12481 gaaagtgatg ttgctcgtgt ccgtattttt ggagaatttc cgaaaggtgc gttggattca
    12541 tttatcagtc ttgaaacagt tgaattggct acagaaaaac aaattagtga ttctttagtc
    12601 aataaaacaa aggttgctca tattggtgtc gacgtagctc gatatggtga tgattctacg
    12661 attctctttc ctagaattgc taccagggca ttggagtatg agaagtattc aaaacgtagc
    12721 accatggaaa caacaggata tgtcatcaac atggccaaga atctaatgag tcaatatccg
    12781 agtattgata aagtgatgat taaagtcgat gacactggtg tcggaggtgg tgtaaccgac
    12841 cgcctagaag aacttataga agacaaacat tatccttttg aggtgtttgg agtgaataac
    12901 ggttcaacat cagaagacga tttttacgat aatttaggta ctcaactatg gggaaacatc
    12961 aaggaaatgt tagaagaaaa tatgacagca aatcttaacg gagaacagcc tgttattgaa
    13021 ttgccttctg atagttcgtt aatcaaagaa ttaagtactc gcaaattcaa aatgacaagt
    13081 agaagtcgta tacgtttaga aagtaaagat gatatgaaaa agcgaaatat tggtagtccc
    13141 gatattgctg acgcactggc tttagcgttt tatgagccac caagtcacta tcaatttatt
    13201 caattttagg aggtgagctt ttgattagta cagtattatc tttagagaga tataagaagc
    13261 tacgtgttaa atatgcaaca caaattgaag atggaatgtt tgatccgaat ggttttatag
    13321 aagatatgaa accatttttt gctgatcgcg aaagaaaata tctagcttat actagcgaaa
    13381 agaatgaaat agataataga ccaaagccta acactgatat tgtaaaagtt aataataaac
    13441 ttcatgctgg tatgtattca attgtcgtag accaagcagt caatcatttt actggtatac
    13501 ctatcaaatg ggattacgat gtatcggaac aaaaaagaac actcattcaa agattaaaag
    13561 ataaattctt aaaaaatgat atagaacttc cgacagttcc agaagctttt aacaaattaa
    13621 caagcaatct tgattccatg agattcgcaa tgcttgattc tgaaactgca acttttcaag
    13681 gagcttgtgg agtagctttc cgattgctag agcctgtgga agaagatgat ggttggaagt
    13741 taagagcaag taatattgaa ccttggagag cagaaagata tggaaatgcc ggaatctata
    13801 tcaaagaaaa gtatgactct taccagaaaa aattttttca agaaatgaaa gttatgacaa
    13861 gaaataaaat tctgacatat gcttgctatg gtgatttgaa ttttgttaca agcggaacgt
    13921 tcaaaaaaat tgatgagacc gataaccctt tggggacgat taccttggca gaatttaaaa
    13981 ataatacgaa tcgttattgt gattttgaag tagctgagga aattggagat gcaattgatc
    14041 gtgctttgtc tgatcaacaa aacgaaatcg aacaatttaa gcttgcgtac atgcttgtta
    14101 ctggcacaac aatgagcaaa ggcactgcta aagaaatgat gaatcagcta gggattatca
    14161 acttaaaagc ccctactgca aaagctgaat atgtcacaaa aaatttagca aaagatttca
    14221 atgaatatca tatggatcta ttgaaaaaac agttttacac catttgtaaa gcaatcgatt
    14281 ttaacgatga ggtgtttaaa tcaaacagtt ctggagaagc tcgcaagtgg caaatcatta
    14341 gcctagaagc gaaaacaaat actaaagagc aatattttag agaaggattg aaagaatgcg
    14401 cagaaacaat tgctgctttt cttaagtttc atgacaaagt agaaattgag cctgaaaaaa
    14461 ttatttttac tttctctaga tctttgccaa ctgatttaag ttatttagct gaagctttac
    14521 ctaaacttgc accatacgta tccaaacgaa ctattcagag ccaaattcca tttgtaacag
    14581 atgttgatta tgaaaatgaa atgatggaat tggaaagtgg aagtgcttat ccagatagtg
    14641 aatacaattt tggcggaggt ggcaatagtg acgatagaaa cgaagtattg gaccaaacgt
    14701 cgagaactgg aggatcaagc aaggctcaaa caagaaaatc agacacttaa aaaattaact
    14761 agtgtatttc ctgaagcact gaaagagata caagcaaaac tattatcaca agctgactta
    14821 cacaatatca cttatccaga aatgatggag ttttacagta caagtaatca gaaaaaatat
    14881 cgtgaatatg tggaaaaaaa ttataagtca ttaaaaatgt atgatgcaaa atacaaagag
    14941 tttatcgatg aattttttcc accatttgac tatgcaaaag tcaatcgctt attacaaata
    15001 cgatcagatg tatttaaaat tcttgcagaa tatgcgatgg atgcagatgt gaatcaatat
    15061 ttttctgatc gcttagagga aattcttcaa agaacatatt cttctaatgc taatgttttt
    15121 gttcaacttt taaacgttga tataccaaat tatttaccag aaaatgaaat taaacattat
    15181 ttgaactatc catggtcagg aaagacattt tcaagaagac tttggggaaa tatttcatcg
    15241 cttgaacaga aactctctaa tgctattgta aaaagtgttg ctagtggaga aggcgttata
    15301 cacgcattaa acaccatgag attagactca gaaatttgtg acatgtttaa gttagaagaa
    15361 tcaaagtata acaaagcgat agaaaatctc gttcgaacgg agtatgcaaa atttgcacaa
    15421 gatggtattg aaaaatcata tttagaaaca ggtattgagg aatacaacgt attgactgca
    15481 aaagatgaga gagtttgccg gatttgtgga ggaaaggcaa gtaagaatcc ctataaactg
    15541 aaagatgctg tcataggtga aaatcgagca cctttccata gtcgttgtag atgtacggat
    15601 gttcctaatt taccaaaatt aggaaaggat attgatgaag aatatgaccg tttatttggc
    15661 gatttattag atgagtttgc acatgattct tttggaatta atttgaaacg gaggaagtag
    15721 aatgaaagat ttttttgaag cagtactaac aattaatgta aatgctgata ttgcagaagc
    15781 ctacaaaaca gctattgagt ctgagaacca tcctaatggc ttgagagacc attggaatgg
    15841 caattatgcc tacgtggtta ttggcgatca aactgttaat tatcaagata atactccagt
    15901 tgataagaat accgttaatt taacgattca attattatct cattcattac caaatttaaa
    15961 agaaacagtt gattggtatg aaaagatggg atgtattgtt gttagaactg actacaaaga
    16021 aggaaagtct agtaattagg cttttttatt ttgtccgaaa tgacgttaaa ctagcgcaat
    16081 actgggcttg gttgaatggt ggggcgcaac tattaaaact caaagcaatg cggggcgtga
    16141 aaacgaatcg tggggcgaaa ggagaatgag catgaaacac aaatcattaa tgccaatgaa
    16201 tttgcaatac tttgccgaag gtgacgatca aaagttttct tttgatgact tcaaatcttt
    16261 tgtggaatcc aatgaagaag ctcaaaaatt tattcagtca caatctcaaa gtgttgccga
    16321 caaacaattg gaagcttgga aacaaaataa cttagataaa attaaacagg ataccatcaa
    16381 ggaatatgag gaatctaaga aaaacaagtc acctgagcaa attcaactgg aaaaactaca
    16441 agctgaattt gaagcagaaa aagcgttgcg tgtgacaagt gataataaag catttgttgc
    16501 agaacaaatt gctggattag aactagatgg agagttaaaa gagtctattt ctcaatttat
    16561 gctaaataat cttgttagtt cggatacaga tttcactaag aatgctgttg aaggttttac
    16621 aagtgttttg aatgcaatta atgagaaaca tgcagatgca ttaaaagaac tacaaatgaa
    16681 gtctgcattt ggtggaactc aacaatcgaa taaccaggtt cagcagaaca atgaaacatt
    16741 aacaaatcca gaagaacaat taggacaaat tcttcaacaa tttaactagg agagtgaaaa
    16801 attatgaaaa aaacatcttt aaataattta gagtatttgg atatttcacc agcgattaat
    16861 gctatgcaag taccaaatac acctttttta agctatttac ttggtgctgg aaaaacagag
    16921 ccagcaaact cgacagaaat taaatggcgt gaatatgata tcaacaacga tgattcttct
    16981 gaaaaacttg agggcggaga atatccagat gctgaatcag gtcgaacttg gtttaacaac
    17041 tatactgaaa tttttagaaa atcaacctct gtatctggta cattagatgc tattaatgtg
    17101 aatggagtcg gaaatgaatt aactaatcaa gtagcactac gtggtatgga aatgaaaatt
    17161 gatttgaacc gaaaattgat tactggtgta aaagctgatg aaaatggttc taaaggtcgt
    17221 cgaatgaatg ggattttgaa cttgatcaat tcagcaaata aggcagaaac agccactgcg
    17281 ggtgcagtaa caagaaaaga tatcgatact ttatttaaat tgatgtatga aaaaggttat
    17341 atgggagaaa aactatgctt gatttctcca gatatgcagg agttaatgac tgatgagtta
    17401 gatggaaaat caacaaaaat tgttcagttc ggggaaagag taacttttgg attgcaaatt
    17461 ggaaatatcg tgtctaatta cggtacaggt attgctctac tagaaccatc attgccaaaa
    17521 ggaacaattg ccgcaatcga tactaattat gtgaaactac gtccattacg tgaatggaga
    17581 gcagaagaac ttgcaaaaac aacggattct agacgtatcg gtcttgtagg tgaatactct
    17641 cttgaataca atgcttcaaa ctctggggca attttaaatt taaagtctga ataaaaggga
    17701 gttagtactc ccttttttga taggaggaat tacagtggta aaaaaagatg aaactaaaaa
    17761 agatgaagtc gtgaaatata gagtaggtaa aactaaaaat tttgttgggt ttgttcatcc
    17821 taaaactcgt agatttatca cagcagattc aaataacgaa tttatcattt ctatagatga
    17881 taaagaagca attgcaattt tggaagatgc aattgatgtt aatgaaattt aggaagtgat
    17941 ctgatggatg aatcgctaaa aacggaaatc attgagtcta caaaagaaga ttttccagat
    18001 ttgagtgaag aacgcataac taatttatta gaaataattt tgctagaaat tgaatcatac
    18061 aacacttgta aaaatgatat ttcatgggaa aagttaaaaa gcgtgattag tgaagtgttg
    18121 tataaaataa taaaaaatga atcagaaaaa acagtatctt cagttagacg tggcgataca
    18181 acgattagtt atgcttcaac aacaaatgat gttagtgagt tacttctagg ctatggtgat
    18241 ttgatacgaa gagttattgg ttgtggagga ttggagtttt tttaatgaat gaagcagata
    18301 ttttagaaac tacttatgaa gatagttgta ttattgaaag actgacggac attgaagatt
    18361 ctaatacaaa tattactatt caagattaca aaaaagtata tgataatcct atttcttgcg
    18421 ctctttcaca aggtcaaatc gatggactag cagtcataga agatggagag atggtaaatg
    18481 tttcaactga cacatataaa ttatttgttc atcctaagat taaactaaaa aaaggagatc
    18541 gaataacaat aactcaaaag gccagtggct taattttttc tctatttgct actaagcctt
    18601 tttactatcc tagtcattgt gaagtgaatt tgataggaag tgagaaaaat gggtaatctc
    18661 aaatatgaat caaatgcaga aaagatcatt gagaatttta aaaatatgac tgtaattgct
    18721 caaaaagaag gaatatcctt cgttaacgat tcaatgaata aagtcgttag tttagctaaa
    18781 ccattaactc ctgtaaaatc aggtaattta aggcgaggat atcgtgtagt aaaagctaga
    18841 aaactatcaa gcggtcgaat tgttggagaa gttataaaca atgaacatta ttttaaatat
    18901 gtagaagaag gtcataggac taaaaatggt ggctttgtca aagggaaatt catgttaact
    18961 cgtgcaacga atcttgcaaa tatgtcttat attcctcgaa gatttaaaca aatggcaata
    19021 aaaatcgtta agaaaggaaa gtaacatgaa agatgaaatc attgctgcaa tcagtagcaa
    19081 attaaaagaa atctatcctg atgggacaat atatcttgat tcagttatgc agtcaactaa
    19141 agatttttat ttcgttttat cagtaatgga atctggaact gaaaatgtag gaattgatat
    19201 tcaaaatgtt tctttcttaa ttgatattgc attgattgat aataacccta atagaaattt
    19261 aattaatgaa ttagtctcac gttgtgggac tttttttaat acgattacaa tcgatgagca
    19321 aatattattt ccaaaagcct atttacctga tgaagcagat ggtgttcaac atattcgttt
    19381 tacattagaa tttccacaat atattgaatg gagtgaaaga taaatgggag aaaaaagaag
    19441 taaaaccgga attatttctg tcgaaaaacc tacttggttt cctttggaag atgagacagg
    19501 gaattttccg gtatatggta ctgcgttgcc aatgggaaca gcagtaagta tcaaaccaac
    19561 agctaattat gaaacaacac aagattatgg ggattcagtg gttcaagatc aatttacagc
    19621 ttttggtggt gcagaagttg aactggaagc aaatggatat actcataaag ttttatctac
    19681 aattactgga gggaaaattg ttaaaggtgg tgccttgcgt tctggagaag atattgcgca
    19741 agatggtgcg tttgcatata gacgtaaaaa atcgaatggg aaataccgtt atacggtctt
    19801 ttataaagga cagtttgctc tagattcaga tgaaacatca acgattgaag gaagtaaagt
    19861 aagttttact catccaactt ggaagggttc atttgtagat gtaccaggac ttggatatat
    19921 gtattcagtt gatgaagatg atgaaggcgt ggataaagca atgatcggaa attggtttac
    19981 aaaagtagca attccaattg aagaagcaga actttcagga ggtacagaat aatgtcaaaa
    20041 tatcaaacaa cgattaaatt aacgaaaaaa gacgaagaag gtaaatatga gcaagtacaa
    20101 tttaaatctg ctgaattttt accaggaaca gttgtagaag atgctgcagg agttatggaa
    20161 gaaatgcaaa cagcgactga taagcaatca gttaaaaaag ctttaagtcg tgcttattca
    20221 tttattgcag atactttatt tgagggacaa tttactggtg aagattattg caaaggaatt
    20281 gatgctcgtg agattgcctc attgacagga aaattattga agtctgttac tgcaggtttt
    20341 gatgaaactt atacagagac gaaaaaaaag taagtgaggc gctcaagtca ccttcattta
    20401 agtattcgat tacttaccga gaattagata taaagacgca attactcgaa gcaggttgga
    20461 cgttaccaga aattgaacgt actgacttgg atgagttaat gcgtcttttt gcttttagag
    20521 atgcggtaaa agagcatgaa gatgttgagt actatgataa tttcactcaa ttttaggagg
    20581 tgatactttg aataacgatg acctaattct gaagatgata ctagatgaat ctggttttac
    20641 tgccggtatg aataatgctg tcaaaaagtt gaactctttt gatgaaacaa tcgaaagaaa
    20701 aagtagaaat agtggcagtt cattaggtag tatttggaaa atatttgctg gaagttttct
    20761 agctagcgga gtaactagaa tcgtaggagc tggctttgat ctaatcaagg gttccataag
    20821 tggagcggtt gatcgagtag atacgatgaa taacgctcta cgaaatttcc aaaatatggg
    20881 atttagtaat tcagaaatta tgaagaatat cggaaagaat gggcttttat ctcaaggtat
    20941 tcaaggactt cctactgctt tgaatgatgc gataagtcat gttcaacttc ttgcttcttc
    21001 tacaggtgat ttaactcgtt caactcaaat atttaaagct ttaaatgatg gaattcttgg
    21061 tttcggtggt tcaactgatc aagttaatga agctgttatt caattatctc aaagtttctc
    21121 aaacggaaaa gtagacgcac aaacttggaa ctcaatgatc aacgctcaac ttggacctac
    21181 tctttctgct attgctaaaa agatgggaat tacaatggga gatctgaaag aaggtttatc
    21241 tcaaggtaag atttctgttg aagaattcca aaatcaatta atagaaatgg ataccaaagg
    21301 tggcggagga cttaaatcat taagtcaaat cgctaaagat tctactaagg gaattaaaac
    21361 ctctatacaa aatgcaaaaa cagctgttac acgtggtgtt ggtgaggtaa tagaaggatt
    21421 aaataaagca ttagtagatt cagatttagg tggatttaag ggaattattg ataaagtggg
    21481 cagttcaatg gaatcgttct taaaagtaat tgctgcaaat attcctacag cagtatcatt
    21541 tttaagtaat ttatttaacg aaattcaaaa atttggttct gctttgaaat tcatgatgcc
    21601 ctttcttgtt cctgcagcta ccgcttttgg agcgttcatg tttcaactta aaggtatacc
    21661 agcaataata aaaagcttca ataattttaa gaatgccata attggcgttg gaaattcatt
    21721 aaagattatg ggggcaatag ctgctgctaa tccatttgtt ttaattattg gtgcagtcgt
    21781 tggtgcaata gcttttttcg gttactttat ggcaaccaat gaagagctta gaaacaaggt
    21841 tatatctatt tggaatgatg tgaaagattc cgtaattggt gtattaaaaa atataaagga
    21901 ctggggaatt gatacttgga attctgctaa agaaatggca tcaaatgcag ttgagggtgt
    21961 caaagatgct tggtcaggaa caaaggaatg gttttctaac acctggaaag gtattaagga
    22021 tggggccaca ggtttatttg ataaaacagt agagacttca agaaatgcag tcgatagtgt
    22081 aaaaaatgca tggtctaata tgaagaaatg gttttctgat acttggcaaa gtataaaaga
    22141 ttcagccaga gaaaaatgga atggaatcaa aggttctatt atgtcagttg ctggtccatt
    22201 gattacaggt ataaagaatg catttttaca tgttactttt tatctagaga ccttatggaa
    22261 taatttagtt gagattggta aaaacgtctt tgagatttta aaaaatgtta tacttgcgcc
    22321 ggttttgttt attacctcca tgatttctgg tggatgggaa gaaacaaaaa ataatatgat
    22381 tgctgtttgg aataatatta aagaaagtgc cataaatatt tgggaatcta taaagaatat
    22441 atttgtaagt tattttacaa atatttattt tgctgcactc aatatttgga cagggttcaa
    22501 gcttacattg ataaatattt ggaatgaagt ggtaaatcaa gctaaatcga tttggttaaa
    22561 cataaagtat ttttttatta atctttggat tgatataaaa tattttgcaa ttcagaaatg
    22621 gattgaattg aagttttcta ttattcaaac ttggatcgat ttaaaatata atgccattac
    22681 tacttggaat aatattaaac agtttttcaa agatacttgg aaaaatatta aagatacggc
    22741 atacaatacg tggatttcta taaaaaatac catgattaat acatggaata acattaagga
    22801 ctctttctgg aatattgtta ctggaattgt taattctgct gaaaatgcat ggacaaatct
    22861 aaaaaatggt gtttcaaatg ctattaatcg ggtaaaagaa atctttaatt cgttaaggga
    22921 agtcaattta tttgaaattg gcaagaacat cattgatgga cttataaatg gtgtaaaaga
    22981 aaagtggaat gctttgaaag atactatcaa aggtattgca ggtaatatca aaaattggat
    23041 taaaggagct ttagatattc attctccatc aagatggatg cgtgatatgg ttggtaaaaa
    23101 tattgttcaa ggtattatcg ttggtattga taaagagcaa agtaagttag atcaaaccat
    23161 gacaaattta gtaaaaacac cgtctgttca acctgtagta aatggaataa gtcacctacc
    23221 aattacacaa acaaagcaaa atatatctgc tagtgaaaca aaagaaattc atttacattt
    23281 aaatgtttat ggagatttac ctgattcaat ggttcggaag attaccacaa aaattaaaac
    23341 agaattgaca agacaaatga aacgagatgc tggtgcagta ggaggaacat tatatgcaac
    23401 ttaagagagg acaatttttt attaatcaac attattcttc tgaatttaat gtgtatattc
    23461 aaaacaggcc tgcttctgtt tcagctagtc gagtaattga attgagagag cgagaaggaa
    23521 atgattctat cattattgat aaaggctatt acaaaaatgt gactagaaag attgagtgtt
    23581 actataaagc accttcaatt gatatggtgc aggagtggga agatcgaatc actgaatggt
    23641 tagatatgtc gtcttatagt gattttattc tttactatga tgaacaatat atttatcaag
    23701 ctgtagtaat agaaggacct gaatttaaag gaacaagaaa aacaggaaat attgtccctt
    23761 ttgaatttac agtgagtatt cgaccattta aggaaaatta caatggtaga tttactattc
    23821 gacaaacaga aacttttgaa atttataacc cagagaagta ttcttcaaaa ccgcttatta
    23881 aattgagtgg ttctggagat gcttcttttt atattaataa ggataaatat gatttgaaat
    23941 cgttggacag agaattattt atagattcta aattagaaga ggcttatcga aaattagatg
    24001 gtaatttaga acatcaggat caggtcacct tatttttaga ttttccattt ttatatcctg
    24061 gaaaaaatga aattaaatgg acgaaaaata ttcattcatt tgaaataatg cctaggtggt
    24121 ggagaaaagt atgaaaccaa gaatatatag tcctactgaa acagatttct caacgaatgg
    24181 cttaggaatt ttaaaggatt gtacaagatg tggaatatat gaagtagcta atggaaaata
    24241 tgaattagag ttggattatc ctttaggaac tagatttgat gaatattttg aaaatgacta
    24301 tcaaataaaa gcaaagccaa acgatcaaga agagtatcat atctttttta ttgatgataa
    24361 agatatagat acttttttaa atacagtaac tatttatgct cagagtcgta caaatcgact
    24421 tggaagacgg gtagtcactc ttgtggaagt ggactctaaa actggtcaag aagcgatatc
    24481 aattattgaa actaaaatgg ataaaaaatc tgacatacga ctttattctg atattacggc
    24541 tgtttctagc acaatctttg aagcgagaaa tgttttaaat tgtattgctg gtgaacaagg
    24601 atcattgctt caatattggg gcggagaaat taaacgtgaa ccatttaagc tttctttgtt
    24661 aaagcgaaga ggtcgcaata atgttggaac gattcggtat ggaaaagata tgtctggttt
    24721 gaaggtcaaa ttagattgga caggtataaa aacaagaatt attccatatg ctgatcctca
    24781 aagtgaagta ggtacgacta atcgaattta tggttcgcca gtagatagtg cctatattaa
    24841 taactatcct gatgtctata cagaacatgt tcagtttaca gaagaacaag gagtaaaaga
    24901 cattaagagc ttaaataaaa tagctaaaaa ttactttaaa acgatcaatc ctggctgtga
    24961 taagcctaaa gtttctatta cggttgaatt tgataagttg actgatagtg aagaagcgaa
    25021 agaatttgcg aagattagaa attatggtct gtttgataca tttaaaatat atcataaaaa
    25081 atataatatt tatcttgaat caaaggttag tggactacaa tacgattctt tatctgaaaa
    25141 aactttgaaa ttagaagcag gagacattca agttgctttt tatcagcaac aagctgtaac
    25201 tattcaggat aaattaaaag attatgcaac gaataattat atgagtgatt ttaatgatta
    25261 tgtttcttca atgattacag gtcaaggcag tgcaggagga tatgtagttt tatggccaaa
    25321 agaaaaacct tccaacatct ttattatgga taatccagat ttagaaaagg caagagaagt
    25381 actaagaatg aataaaaatg ggattgcttt ttctaagaaa ggatggcggg ggccttttaa
    25441 ttcagcttgg acattagata gtatatttaa tgccaatttt atacaaactg gattaatcaa
    25501 agcagatatc tttcaaaatt cttttaacaa gactggagat gtattgaaat tagttaatgg
    25561 actactccaa atttggaaca acaaaaagaa aataatggag ttaactaaaa aaggaatgga
    25621 attttggaat tctaagggtt caattggaac gattggaaca actgattctg ttggtaatcc
    25681 ttttcctggg gcttctactc caacccctat tgaagataat tctttagtta ttcgtacaaa
    25741 tggagacggc aaatatattt tgatttctcc taaagtagga aaaggattag ttttattagg
    25801 aaatggtaaa gcaatttatt ttggagactt agatgtacaa ggaaaactta cagttaaagg
    25861 aaaagaaata attcctggac aaggtggtgg tccatcggga ggtggagaat ctactggtgg
    25921 gtatcctagt gaattaaaaa cagatgcaga aaagagagct tggagaattt acgatatttt
    25981 gtgtaataac ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga
    26041 aacaggagga acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt
    26101 tcagtgggat ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta
    26161 tgttcaaaac ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca
    26221 agttcgattg cttatttgga catttacaaa tggacaatgg atgggcgtag tacaacctac
    26281 gacggttgat ggatttaagg cctgtactga tccaagacaa gcagcatatg cttttgaacg
    26341 aaactatgaa cgtccggcag cgacacatcc tgaacgtcaa gattatgcag ttaactggta
    26401 taacaaattt aaagatttaa aaccaggagg agctactgga gaagcaggac taaaacattt
    26461 agagtctttg attggacaac gaattggcaa tggtcagtgt tatggcttgt ctgcagaata
    26521 ttcaggatat ctgggtggtt gtggcatggg tgctggaaca aaatatggtt taactcatgt
    26581 gataggaaat acttctgcag catctgatat tggtattgcc tatgattggt ctgctgttgg
    26641 ttggaaagtg attcaaaacc ctagatatga tcaattagta gttggtgcaa ttattaattg
    26701 ggcaagaggt ggacaagtgg gttcatggtt tgcagatgga acttatggac atactggcgt
    26761 tatccgaggc ttagctaatg gtcgtatgca aacttatgaa caaaacacag agttaggtat
    26821 gatttgtgga aagttagatc gccagtatta tagtgcaagt gcaatttctt ccattgtcat
    26881 accaccaaaa tagggaggtg atttaatggc aaagtggaat gtcatattaa gtacaacaga
    26941 accctataat tacgtgggga tgattcaagt tcgacaaggc aataagaata cagaggttat
    27001 ggaagcgact atagttgaaa atggtcttcc ctacgattta tcagaatgta aggtatattt
    27061 tgaatcagtt gtaggtggga aatatccagt ccaattagaa acaaaaattg tggatgctaa
    27121 aaaagggaaa attaactata tttttgataa atattccatg cagtgtttac atcgacaaac
    27181 agccaatttc attatattta aaggagaaga cttgattgga acaactcaag acttctctta
    27241 ttttgtcatt aatgctgttt caaaaacaga aggagaaatg ggttcttatt ggcaatcaat
    27301 cgaagattta attgcggata tgacggactt tattaatgaa aataaaggcg attttacgga
    27361 ctggatgaat gaaaggaaag aagaatttga acgttggaga caagaacagg aacacagttt
    27421 ccaagattgg agagaaggac aagaatcaga ctatttggca tggtttgaat caatcaagga
    27481 tattttaaag acgattgatc caggtggagt catgttagcc gaactaacgg atgcgcgagt
    27541 agatattcaa ggagttcgtc atgcgtctat ttcagagcgt ttgctggcag atatggacta
    27601 tttatatcag aaattgcgag caacgctttt cacgattgaa tacggggaga ttgaagtgac
    27661 tgatattttg caggatgatc tcttttcaga taatcatgaa gtcgaaaaag ttggaactgt
    27721 agcattcccg attgaagaag gagccttgat catcgcaacc gttgatgatc caaagcaaaa
    27781 tgtgttcact cttgagaaag ttggggtgat ctaatggcta aaactaaacg aatgatggaa
    27841 acggatgaaa aaacgggtgt acaacgccaa ttctttccaa tcacacatgc ttccgcagtt
    27901 cttgggttag aagaaataat agcaggagaa gcaacagttt tatctgttaa tggaaaaatt
    27961 ggagccgtcg tcattactaa agaagatttg ggattagaga atgttctcac agaattaccc
    28021 tatgcaagtg aagaagatga cggcattatc acggcagaaa tgtatcaaaa aattttaaac
    28081 agtggagaag gtgactacgt gttgccagtt gccactatcg accgtttggg tggcataaaa
    28141 gttggtgaat tattgacgat tgatgagaca gggaaagtct ctgcagtcag acaatctgat
    28201 gtcaattttt cgctggagtt aaaagaaaaa ctcgattcac tgaaaaatta tactgctgga
    28261 gaaaacatca ctattgatga agatggaaca attagttcta caggtggtag tgggactggt
    28321 ggtgtcaatc agtcatatgt agatcaaaaa ttccaagaag ctgtaaatca agcagaaaat
    28381 tacacaaacg aaagaattcc aaattttact tttgaaaaaa ttggggaggt atagagaatg
    28441 acagatatcg taaaaataaa acaaagcaat gtacaggttt atccacaaac tcattggaat
    28501 gctatagaag gcaaaccaac aacggtgaag ggagataaag gcgatcctgg ccaagcagca
    28561 acaattacca taggaaccgt ttctagtggt tcaaccgctt ctgttacgaa tgtaggaaca
    28621 tcatctgcag ctagatttaa ttttgtttta ccaaagggag ataaaggtga tcctggaata
    28681 aatgccacaa ctacagctgt agctacaact acagcaaatg ggttgatgtc gtccacagat
    28741 aaaactaagt tggatggaat tgcagctgga gcacagaaaa atccaggtaa tgctacaact
    28801 acgacagcag gtttaatgtc agcaactgac aaagctaaac tcgatggatt agccaatatt
    28861 acatttgaga aagtggggac ggtttaatgg ctgatattgt gcaattaaaa gaagacggag
    28921 ttgctaaata cttaaaaacg catgtagaag ctattgatgg taaagaagca ttggtgcaga
    28981 cagatggaga ccaagccatt gcaggacata agaatttttc aggttctgta acaatcaata
    29041 ataaacgtgt tttgacgact gatgataaca gatatgaagt ggtaaatctg gttgtcacta
    29101 acggtaatac agggacagca aagctttatc gtgaaggaaa aacagtttct atatattttg
    29161 tggctttaaa cggaaaaagt agtggcggga atgattcggt tattttaact gttccagaag
    29221 gctatcgg
//
LOCUS       DAIGWC010000032        29098 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.032, whole genome shotgun sequence.
ACCESSION   DAIGWC010000032 DAIGWC010000000
VERSION     DAIGWC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29098
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.032"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..1030)
                     /locus_tag="NOB74_001441"
     CDS             complement(<1..1030)
                     /locus_tag="NOB74_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1220635.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="NOB74_001442"
     CDS             complement(1112..1801)
                     /locus_tag="NOB74_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI1220636.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="NOB74_001443"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="NOB74_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HCI1220637.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="NOB74_001444"
     CDS             complement(2328..2831)
                     /locus_tag="NOB74_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HCI1220638.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="NOB74_001445"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="NOB74_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HCI1220639.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="NOB74_001446"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="NOB74_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HCI1220640.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="NOB74_001447"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="NOB74_001447"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HCI1220641.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="NOB74_001448"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="NOB74_001448"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HCI1220642.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="NOB74_001449"
     CDS             complement(6443..7462)
                     /locus_tag="NOB74_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCI1220643.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="NOB74_001450"
     CDS             complement(7635..8540)
                     /locus_tag="NOB74_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI1220644.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="NOB74_001451"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="NOB74_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HCI1220645.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="NOB74_001452"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="NOB74_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HCI1220646.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="NOB74_001453"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="NOB74_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI1220647.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="NOB74_001454"
     CDS             9753..10397
                     /locus_tag="NOB74_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI1220648.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="NOB74_001455"
     CDS             complement(10453..10956)
                     /locus_tag="NOB74_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCI1220649.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="NOB74_001456"
     CDS             11553..12518
                     /locus_tag="NOB74_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCI1220650.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="NOB74_001457"
     CDS             complement(12617..13789)
                     /locus_tag="NOB74_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220651.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="NOB74_001458"
     CDS             complement(13776..14921)
                     /locus_tag="NOB74_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220652.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="NOB74_001459"
     CDS             complement(14935..15867)
                     /locus_tag="NOB74_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220653.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="NOB74_001460"
     CDS             15984..17063
                     /locus_tag="NOB74_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI1220654.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17678
                     /locus_tag="NOB74_001461"
                     /pseudo
     CDS             17060..17678
                     /locus_tag="NOB74_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(17788..18015)
                     /locus_tag="NOB74_001462"
     CDS             complement(17788..18015)
                     /locus_tag="NOB74_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI1220655.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18118..20706)
                     /locus_tag="NOB74_001463"
     CDS             complement(18118..20706)
                     /locus_tag="NOB74_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HCI1220656.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20726..21385)
                     /locus_tag="NOB74_001464"
     CDS             complement(20726..21385)
                     /locus_tag="NOB74_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI1220657.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21434..21937)
                     /gene="trmL"
                     /locus_tag="NOB74_001465"
     CDS             complement(21434..21937)
                     /gene="trmL"
                     /locus_tag="NOB74_001465"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HCI1220658.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22158..23024)
                     /locus_tag="NOB74_001466"
     CDS             complement(22158..23024)
                     /locus_tag="NOB74_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI1220659.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23133..23774
                     /locus_tag="NOB74_001467"
     CDS             23133..23774
                     /locus_tag="NOB74_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HCI1220660.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23836..25197)
                     /gene="mgtE"
                     /locus_tag="NOB74_001468"
     CDS             complement(23836..25197)
                     /gene="mgtE"
                     /locus_tag="NOB74_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HCI1220661.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25215..26114)
                     /locus_tag="NOB74_001469"
     CDS             complement(25215..26114)
                     /locus_tag="NOB74_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI1220662.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26116..26913)
                     /locus_tag="NOB74_001470"
     CDS             complement(26116..26913)
                     /locus_tag="NOB74_001470"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HCI1220663.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26891..27595)
                     /locus_tag="NOB74_001471"
     CDS             complement(26891..27595)
                     /locus_tag="NOB74_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HCI1220664.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27726..28301
                     /locus_tag="NOB74_001472"
     CDS             27726..28301
                     /locus_tag="NOB74_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HCI1220665.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28419..29096
                     /locus_tag="NOB74_001473"
     CDS             28419..29096
                     /locus_tag="NOB74_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCI1220666.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8562 a         6167 c         5231 g         9138 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgcgaa acccatcgtc ccgatgtttt gctgacggac atccgcatgc
    17221 ctaaacaaac gggcatcgat gctgccaaag aaattttggc taaatttccc aaagccatcc
    17281 ttttgctttt gacgacattc aaagatgaag aatacatccg cgaagcattt tccatcggtg
    17341 tcaaagggta tttaatcaaa cagaacttgc aagcgattat tccttctgtc aaatccgctt
    17401 ataatggaca ggccgtattt ggtaatgaaa tcatcgagac tttcactcaa atgatgaaga
    17461 ataaaccgac gattgatagt catgcttatg cttcttttag tgaacgtgag cttgcaatca
    17521 tcaaagaagt agctgccggg aaaaacaata aagaaattgc agatgccttg tacttgagtg
    17581 acggcactgt tcgcaattac atcagccaat tactagaaaa gctagattta cgggatcgca
    17641 cgcaattggc tatctatttt tatcagcatt tgcaataagt cttatctaac acaaaaaaac
    17701 ctgaatgatg ctccttcgca tcattcaggt ttttttcaca tcttctattc aattgtcccg
    17761 caaaccattt cctcacgatt gaaagaatca aggattcgca gggctgccag gattcgttgg
    17821 attgttcggc gtgttaggcg gaaaaatagg cgccttgtct aacgtttttt ctagttttga
    17881 ttcttcacga tcgtctcgtt ctacatcagg actttcattc aatttgaatt ctttttccat
    17941 ctcatctaac tttttaaagt cattgccaga ttcttttgct aatttcgcta atttatcttc
    18001 ggtttcttta gccataaagt aacgcccccc ttttgatttc agcttagcat atcacactga
    18061 aaaaacaaaa gaaaacgcta accaacgatc atttttagct atttctcatc tttaaaatca
    18121 agcatttttt gccggtataa aatcgtaggg agaactgttt tccataccaa tcatcggatc
    18181 tactaactgg ttatcgatca cttctgctgt aagaacgaaa tctttagaaa cagcaggttc
    18241 tacctcttct ttcttttctt ctccaacaaa tgaagaaaac agatctggtt ccactgtttc
    18301 cattacttgg tttttcgttt cattcgtccc actgtcatct tctacaggta gcttttcttt
    18361 tacaacccgt ggctcttttg tatagttccc atcttcaaat ggatcatttc cgaccaaaga
    18421 atcttcataa gctgctagtt tggtccggag agtgatattc attttatcat tatccatgat
    18481 ccttgatttc aacgtagtca tccggcttgc tgattcattc gctacacaag tgacataggc
    18541 ttgctcttcc cctaacaaaa tcaacagttc cttactgcga gtcactgccg tgtagagcaa
    18601 attacgctga agcatccgct gatattgatg gaccatgggc aaaataacca tcttgaattc
    18661 actgccttgt gatttatgga ttgagcaaca ataagaaaga gtgattttat tccattcgtt
    18721 tcttttataa gtgacctcat ttgcatcaaa ctggataact aattcatcca ctttatcttc
    18781 agaatctttt gccaagatga tacccgtgat ttctcccata tctccattga atacattcaa
    18841 ttcgggagta ttgactaatt ggaggacttt gtctcctatc cgataaacgg tgtcgttcca
    18901 atgtacttcc ttttttccag gtttccctgg attgaatatc tcctgcatca ttttatttaa
    18961 cgcatcgatc cctgcaggtc cccgatacat tggtgctaat acttggatat cttgtgcacg
    19021 gaatccctta tttttcgctt tttccacaat tttagagatc aagggttcaa tttgataagc
    19081 atcacttcgg aaataggaac gatctttttg attctttgtg aaatcttttg gcagacgtcc
    19141 ttctttgatc tcatgggcaa gaggaataat actagaacca tcaccttgcc gataaatctg
    19201 attgagttcc attttgggaa tttgttcgat ttccaaaaga tcatggagta cttgaccagg
    19261 accgacagag ggaagctgat ctttgtctcc tactaagata acttgcatat tcgtcggaat
    19321 cgctttgaat aatgtgttag ccagccatgt atcgaccata gacatctcat caacaatcaa
    19381 aagtccgcct tctaattctt tcgtactgac tgaaggtgtt ttttcccgtc cattcagccc
    19441 cagaagacga tggatcgtac tggcaggcag acctgtcgtt tcgttcattc gtttagctgc
    19501 tcggccagtt ggtgctgcaa gtagaatagg aaaaatttct tgggtatatt ttgaaggatc
    19561 caattccagt ccgttcaact ctgcaaaaag attgacgatt ccgttgatca cagtagtttt
    19621 ccccgtacct ggtcctcctg ttaaaataaa tagaggggaa cggattgctt cagcgatagc
    19681 ttgttcttgc gaaggtccat actgtatgcc gaatattttt tcgatacgcc gaatattctt
    19741 ctgcacttct ttttcaggat aatggatttc ttttttacga ctgagaaggc gctggatcga
    19801 attaccgatc ccccattcag aaaagtacaa actgttttcg taaagattag tctcttcttg
    19861 ttgtatcttt ccttcttcaa caagttggat aattacagta gcaacctgat caggctggat
    19921 ttcaattggg cgacttgttt ctaaaatacg gatcgtttgc tgaagcaatg tctccgccgg
    19981 tacgtatgta tctcctgttt gaactgcatg ctgaaaaatc tgatgcaaga tagctgctcg
    20041 aattcttctc ggtgaatctg ctgcaatacc gatttgttcg gctagattat ctgcacgttt
    20101 gaacccgatt ccttctatgt cttcgactag ctggtacgga ttttcttcga tgatatccaa
    20161 agactcgttc ttataggcct ggtagatact gaaagctaac tgactaccga acccgtaacg
    20221 attcagtccc atgatcactt gatccatccc gtggtttagc cgaatcgtct cagcaagcat
    20281 ttctcttttt ggcttcgtca aaccggagat ttgttttaat accgaaggat cagcaatgat
    20341 tttttcgata gcatcttctc ccagcaattc tacaattttt tctgctgttt tcttcccgat
    20401 tcctgggaat ttttcgctgg aaagatacgc tacgatccca tttgcagttg ttggcttttc
    20461 ttgctcatat ctttcgagtt taagctgcct tccgtattta ggatgatcca ctaattctcc
    20521 ataaaaacga taagtctcat tttcttgaat atcgccgaaa cttccggtga ctacaatctc
    20581 tttttcacgg taatcagctg tggtttcact gatgtgtacc aaaagcactt tgtaaaaatt
    20641 actaggattt tgaaaaaaaa tcgcggcaac tgtaccaacg aaataaggca tttcttctgg
    20701 ctgcatcgga agccgcctcc ttcttctata gtaaaggttc tggtgctgtt tcagttccta
    20761 aaaaatctgt ttggttccat actttcagtt catatggcaa taatctgcaa ggctcttcag
    20821 tctctaaaat cgtcaaacta ctattgaaca atccacccat ttcacgcaac tcacttagct
    20881 cttttcctgt catccattga atggctgcag ttaaagaagc tccatgtcct acgaataaaa
    20941 gtgggccatc tttatgtcgg gcaaccgcat ctgctacaac agtttcgata cgtgtgattg
    21001 ccgattcaat cgtttctccg tgaaaaggag aaggatcata cagatctaaa tgattacgca
    21061 aattcggcag attatccgga tatttctggt acatttcatc gatcgactga ccttctaaag
    21121 tacccagccc tagttctctt agcttatctg tataaaaaat ctctaccgga cgagcaagct
    21181 ctttgttgat accttctgct gtatcacgtg ctcgctttgc tgtactggaa taaattgctt
    21241 taaaaggaac atattttacc tttttcccaa atgctttgat ttcttcgtaa ctttgtggca
    21301 aaagcggaga atcgccattg ctcccttgaa aacgtctttc ctgattccat tgtgtcttcc
    21361 catgtcgggt aaaatatagt tccatacgca gcaaactcct gtctttcttt tattttactc
    21421 tataataaac tgtctaatcc agcttgtcat tttcatagtg atgcgtcaat tctaaattag
    21481 ggaatccttg ctggcgaagt gcttcataca ctatcattgc agctgtattc gataaattca
    21541 atgagcggac atgctcatca ttcataggga tgcgtaaaca cttttcttcg ttttcacgca
    21601 taaatgtttc tggcaaaccg gttgtttctt ttccaaataa aaagaagtgc tcttctccat
    21661 cagcaaaatt ttcgtcacta tatactttat gggcaaattt tgagatcaaa tgtagtttac
    21721 gattacctaa aaatgttaaa aaagcttcta aattactgtg gtaagtaata tttacatcat
    21781 tccaataatc caaccctgcc cgttttagat gtttgtcatc agttgaaaaa cctagtggct
    21841 cgattaaatg aagcggagta ttcgtggctg cacacgtacg ggcaatattt ccagtgtttg
    21901 cagggattaa tggttcaaat aaaacgatat gattcatcag gatcattcct ctcatattta
    21961 tgttcgtttc tattttctga caatttgatt tttgcataaa aaaaaacgta tcaactcggt
    22021 gtcagtcact gcgagtcgtt acgttagtga agctcttctc actaactttt atcagaacag
    22081 gaacctgata aaaaccaatg aaaaaacaac ttgttgctaa tataacaccc tcaacttttt
    22141 tttgcaacct ctactcatta aaaactgcta gaaaaacgtt ttctcttagt tccttttaat
    22201 aattctatgt caattgtaat cttcttcaaa ggattcttat ataagtctgc tttgattcgc
    22261 tcttctacct gccattctaa aggtgacatg gccaaaagat ctttttgatt ttcctctggt
    22321 atctcaaatt cataggttac acgctgacgt tcagttaatt tcattgcttc agcaaacttg
    22381 gctactacac gttcattgga ataactctgt ttttcaggtt gattcggata aaaagcctga
    22441 cgtagttcct ttaaataatt ttcttgtggc accaccttca acacttctcc atcttctgag
    22501 agtacacgtt ggaattcttg gtaatgagaa ggcgaaaaga tatttaaaac cgcgttgaat
    22561 gtttgatcag caaacggcaa attggtcaaa tcagctacac accaaaatgc ttcggcagat
    22621 tgttctgtag ctgcgtagac tccttctttt gaaatatcaa atccaacagc attttgaatc
    22681 tttttcaatt ttgaaagttc attcaagaag ctaccttctc cgcagccaac atctaatagc
    22741 gagacttctt caggtaaatg ctgcgcaata gtctcaataa cgggctgata catgccagat
    22801 tggatcattc tacgccttgg aacgaacatt ccttgatcgt attctgtttt aaccgcatgg
    22861 gataaaaaat aaagtgttcc ttttttggaa aggtcaaaac ggtgattatt tttgcatatc
    22921 aagccattat cagacttttt tacttcttct tggcaaaccg gacagcggaa cagctgatga
    22981 ttttctgcca aaaactggcg tcctcggtca atttttttta acatagttcc ccctcatttc
    23041 tgttttatct taccgttaga tgctcacttt ggcaactgct aaaaatatga tacaatgcct
    23101 agaagaaagt gaaagataaa ggagaagatt agatgatcaa agaattttgc gctgaaaact
    23161 acacatctat tcctctagca attgctagag gagccgatcg gatcgaattg tgtgacaact
    23221 tagcggtcgg tggcacaacc ccgagtactg gtgtgatcga agaaacgtta agttatgctg
    23281 gggaaaaaga tatccccgta atgacgatta ttcgtcctag agggggcgac ttcgtctata
    23341 acgatatcga attgaaaatc atgcatactg atttgattga agcaaagaaa ttagggacgg
    23401 atggcgtagt atttggttgt cttactcctt caggctggct agacgaagag gccttagaac
    23461 tattgatcga aacagcagaa gggttgcaga tcaccttcca tatggctttt gacagtattc
    23521 ctgaagatcg gcaattcgaa gcaatcgatt ggctggtaga acatggtgtt gaccgtatct
    23581 tgactcatgg cggtcctgct gacaaaacta ttgtagaaaa tttcccacgg cttaaagaat
    23641 tgattgccta tacagatggc cgcttaatca ttttgcctgg tggtggtgtc actgcagaga
    23701 atgcagcaca tgtagctaaa gaattgaacg taagcgaagt acacggaacc aaaatcgtgg
    23761 atcttcagtt ataatcttat aaacaaaaaa acatttgcaa caggcataat gcttattgca
    23821 aatgtttttg tttttttaca taaaatagcc cataaataaa gaagcaatat tgaaataaat
    23881 cagtacactc gtcaaatcgc tcaaagtcgt gataaaggga ccgcttgcta ctgctggatc
    23941 aaatcctaga cgatccatta gcatcgggat taaactacct gcaagattcg ccactgtgat
    24001 tgcaaatagc atagccatcc ctatgacaaa ccccaagata aaattatgtt tccaaaaacc
    24061 tacgattaga aaaatcgtga tccccgtaac agctcctgtg acaacgccgg tcaagacttc
    24121 agccaaaaca agtcgaacaa atccatgatc tttctcatca gaaatcgcaa gtcgacgaac
    24181 agccacagct agcgactggg ttccagcatt accggcagtt cctgtaatca gcgaaatgaa
    24241 gactgctaaa atactcgctt cacttaccaa gtcttcatag tgactgatta aagaagcggt
    24301 cgacatacct aaaaacaaca gagtgatcag ccaaggcaaa cgtcgagacg ctgcctttac
    24361 tggattttca ttaatttctt ccacattgac cccggcaagt cctgaataat cgctagcagc
    24421 ttcatcatca ataacgtcga tgatatcatc gactgtgacg attcctaaca aatgatcatc
    24481 ataatcggta acaggaagag ctaagaagtc ataatctcta aatgtttgtg ccacatcttc
    24541 ttggtcgtcg cctacatgaa ctgaaagcac tcgttcgctc atcagatcag aaatcattgc
    24601 gtcgtcatca ttcacgatta ggtcgcgcag agaaataacc cctactagct gaccttcttg
    24661 attaacgaca tagatgtaat agattgtttc agctacatct gcttcgttct tcagcacgta
    24721 catcgcagag cgaacagttt gattggctac gatcgaaaca aattcagttg tcatgatcgc
    24781 gccagccgtt tcatcctcgt aatggagaag ttccttgatt tcactggcat cgtctgccga
    24841 catcaaactt aaatatttag caatttgctt tttatccagc gtattaagca agtcaacagc
    24901 attatctgta tacatctcag aaagcatatc agctgcatag ctaggacgca tttcatctag
    24961 gtattctttc atatgttcgt tgtcttcttc aatcacatcg aacatatccg ctaattcttt
    25021 aggcgacaga taggaataga tcagctgcct gttctcttct gtaagagatt ggtagaattg
    25081 cccctgctca tagatatgca tctctaaaaa actgtttctg aatgcctgaa tattattttc
    25141 ccttaaatct tgagtcaact gggcaaatct ttcctctaat tcttgatttt catccaaacc
    25201 aatctcacct cgccttattc ttcaaaccgt ctcacaactg cctccatgtc tgcggctaaa
    25261 ggctgcttga actccagcaa ctcttctgta aatggatggt aaaaacgcag atcataacaa
    25321 tgaagggctt gtctttttat tcccagatcc attcgcccgc catacatatc atcaccgagc
    25381 agggcacagc caattgcgga aaaatgaact cttatttgat gtgtccttcc tgtatgcagc
    25441 tggatatcaa ctaacgcgat ttctgttagt cgcttctcta tccagtactc agtctgtgcc
    25501 gaacgtcctt catcagagac cattcgcttc aatagcgaag aataatctcg ggcgatcggc
    25561 aaatcgatat gtccatgtgc cgataaatct gaaagccttc cactgactaa ggcctgatat
    25621 tttttcacaa acttcttttc acgaagttgc atatctaatt ttgcgtgcgc aaatccatgc
    25681 tttgcaaaaa gcatcaagcc agatgtatcc cgatctagtc gcgtcaccac atggattact
    25741 tggttttcgt aaccttgttt tttataataa gcctttacac gattagccat tgtcccattt
    25801 ggatggtatt gggcaggaat agacgaaacg cctgctggtt tatttactac cagaacgtgt
    25861 tcatcttcat acacgatatc gatcggtgtt tcatccaaaa gtacggtttc atgttctcct
    25921 tcagcaggaa tcacaatggt taccttatca tccttagcta gagaaaacaa gacattttct
    25981 acttgatcat taactttgat ttgaccgcct tgaaatttta ttttcgctaa cagacccttt
    26041 gagatccctt tttcttttaa aaaatatttt acttgctgag aatgatcttt ctcataatcc
    26101 catgtaaact gcatatcaat cctcactaat aaaggcatct ttcacacgat gccaaaaatg
    26161 catatgtcga taagaagcaa aatggatccg ttcttctgct attcgataat aaattgagcg
    26221 gatatttgct tttgcgacat tcaattgatc aaccgttaca agataatctt ctgtattttc
    26281 caattttatt tctagccatt catcatgggc aatcacgatc ggagaaccca aagtacgaaa
    26341 cactcgatta ttcagtgaag caatctctgc caactgaaag gcattgatac taggatggat
    26401 cacagcaccg ccgacacttt tattatatgc tgtcgaacca gtaggcgtag aaatcgtcaa
    26461 tccatctcct ctaaaacttt caaacagctc gtttttgatg tatacatcgg ctaccatcgt
    26521 acgattggcc cgtttaatcg ttgattcatt cagtgctaaa aaatgctggt ccggtgtttc
    26581 atccaaataa ctgatccgaa catccagcaa gggataacta acactttgtt cccggttcgt
    26641 tcgtaagctg tctactagtt cttccagctc gtaatcccgc caatccgtgt aaaaccctaa
    26701 atgacctgta tgcacgccca agaaacgcac atcattcaga caatgactgt agtgatggaa
    26761 cgccgacaat aatgtgccgt ctccgccgac tgagatgacc aattctggct catgatcatc
    26821 tcgttgaatc cctgcttgtt ctaaaagtgc gttcaaacgt tctgtcactt ctatagtctt
    26881 tgcttcttta ttatgaacga tcgctacttt catcccctgc ctcctctctt tcgctttctt
    26941 tcttcaaaag cgttcgatag tagacatcat ctgattttcc tcttccatgg gagaataacc
    27001 gctgtgcttc ttggatttct tcacggatac tggacatctc ttcatccaac tgataggcag
    27061 cttctgccgc acgctgaagt cgttcactca tttcttctgg aaaaacgcct tgatatttat
    27121 aattcagcga atgctcaatc gttgcccaga aattcatcgc aagagtccga atctggattt
    27181 ccgccaaaat tttcttctca ccgctgatca gctgtacagg atactcgatc accagatgat
    27241 aagaacggta gccacttgct tttttatttg tgatgtaatc tcgttcttgg agaactttca
    27301 tgtcttttct tttacggatg atctcaacaa cttgatggat atcttctaca aactgacaca
    27361 tgatccttaa cccggcaata tcagacattt cttcttctaa acgtcccatt ggaatatgcc
    27421 gtaattgtga ttttgttaca atactatcga ctggcttgac tctcccagtg acaaattcaa
    27481 tcgggacatg tcgattttgt tcacggaact gtttgcggat cccccgcagt ttcactttca
    27541 attctgatac agtttgttca tatggtgcta aaaatgcttc ccaatctcgt tccatagctg
    27601 atacctctac ttcattaaca ttcattgttt attctaccat atatgcaaag ttttttcgta
    27661 ctcttgattt atgcattgac caaaaaaaga aaattaggca aaatagacaa aaaggagtcg
    27721 atcaaatgac acaaatgctt gaaatcgaat ataaatctat gctgacaaag caagagtacg
    27781 agatattcat cgctcactat caattaacag ataaagattt ccgtgtacag actaatattt
    27841 atttcgatac cgttgatgaa cagctgaaga aacaaaattg tggcctacgg atccgtttcg
    27901 ttggtcatca agctgaatat acattaaaaa cacctgctga aaaagggcgt ctcgaaacaa
    27961 cggatacctt tataacagaa gaagcagaag catttatctt cgaaaaacgt ctgcctcgtt
    28021 caggcgcagt ttttcaaaaa ctttctgatt tgaatatcga tcctgcttca ttaatccaaa
    28081 ccggaaagct tacaacaaaa cgagctgaat tccctattga agaaggactt ttagctattg
    28141 atgaaagctg gggagacaat ctacacgatt ttgaactgga actagaggta ggggatgcat
    28201 ctgtgggaaa aattgctttt ataaattttt taaaacgttt ttctttacct tatcgtcctg
    28261 ctaagaacaa gatccaacgt atgcttgaag ctaaaaatta gaaacctttc attttcacaa
    28321 ggcacttgag ttcatttttt tacttttttc tgttaagtta taggatgtga aagaatctag
    28381 tcactagttg tatagaatct attttggggg agattcatat gatcgaaatc tatttatttg
    28441 ttaatccttt aggggaatac tgtttcgaaa tggaacaaca gttattacaa tttatcgaag
    28501 aagagtacgg gacaccatca aaagaaaaga tgcaatttcg ctttcttcct ttggtcaatt
    28561 tgcagacaat tggggatgtc atgcaacaaa aaggaatttc tcagaacaat cttgaggaac
    28621 gtaatcactt attctcaatg acttattctg cagcattgga ctgcaaagcg gcgcagtttc
    28681 aaggaaagaa aaaaggccgc cgttttttga tcaaattgca agaagcagtc ggctgtaatg
    28741 acataccata ttctcaagaa cttgctgaat ccatatttga agaaatcggc ggcgatttga
    28801 atatgtttaa agaagatcgt cagtctgact tcgttaaaga agtattcttt tctgatcaaa
    28861 aaattgctcg ggaaatgggc atcacaaaac acccttctgc agtcgtttac aattatgcct
    28921 gcgaccgtga ttttggtgtt ttagtagaag taaaaggtac aagtagcctt tggagaatca
    28981 cagagctgtg taaaacaaca gataactcat atcaagtttt taatggtgaa catttacata
    29041 caaatgattc tcagttccat tcaagaacta gccatttaca cttgctttct aattaaaa
//
LOCUS       DAIGWC010000033        28211 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.033, whole genome shotgun sequence.
ACCESSION   DAIGWC010000033 DAIGWC010000000
VERSION     DAIGWC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.033"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(101..796)
                     /locus_tag="NOB74_001474"
     CDS             complement(101..796)
                     /locus_tag="NOB74_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HCI1220667.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(886..1986)
                     /gene="ychF"
                     /locus_tag="NOB74_001475"
     CDS             complement(886..1986)
                     /gene="ychF"
                     /locus_tag="NOB74_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HCI1220668.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(1995..2186)
                     /locus_tag="NOB74_001476"
     CDS             complement(1995..2186)
                     /locus_tag="NOB74_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HCI1220669.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(2207..3097)
                     /locus_tag="NOB74_001477"
     CDS             complement(2207..3097)
                     /locus_tag="NOB74_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HCI1220670.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(3084..3851)
                     /locus_tag="NOB74_001478"
     CDS             complement(3084..3851)
                     /locus_tag="NOB74_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI1220671.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(3863..4576)
                     /gene="rsmG"
                     /locus_tag="NOB74_001479"
     CDS             complement(3863..4576)
                     /gene="rsmG"
                     /locus_tag="NOB74_001479"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HCI1220672.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(4808..6709)
                     /gene="mnmG"
                     /locus_tag="NOB74_001480"
     CDS             complement(4808..6709)
                     /gene="mnmG"
                     /locus_tag="NOB74_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HCI1220673.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(6726..8123)
                     /gene="mnmE"
                     /locus_tag="NOB74_001481"
     CDS             complement(6726..8123)
                     /gene="mnmE"
                     /locus_tag="NOB74_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HCI1220674.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            8422..8805
                     /locus_tag="NOB74_001482"
     CDS             8422..8805
                     /locus_tag="NOB74_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220675.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(8973..9731)
                     /locus_tag="NOB74_001483"
     CDS             complement(8973..9731)
                     /locus_tag="NOB74_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HCI1220676.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(9749..10567)
                     /locus_tag="NOB74_001484"
     CDS             complement(9749..10567)
                     /locus_tag="NOB74_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCI1220677.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(10564..10920)
                     /gene="rnpA"
                     /locus_tag="NOB74_001485"
     CDS             complement(10564..10920)
                     /gene="rnpA"
                     /locus_tag="NOB74_001485"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HCI1220678.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(11038..11172)
                     /gene="rpmH"
                     /locus_tag="NOB74_001486"
     CDS             complement(11038..11172)
                     /gene="rpmH"
                     /locus_tag="NOB74_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HCI1220679.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            11696..13030
                     /gene="dnaA"
                     /locus_tag="NOB74_001487"
     CDS             11696..13030
                     /gene="dnaA"
                     /locus_tag="NOB74_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HCI1220680.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            13228..14358
                     /gene="dnaN"
                     /locus_tag="NOB74_001488"
     CDS             13228..14358
                     /gene="dnaN"
                     /locus_tag="NOB74_001488"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HCI1220681.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            14587..14829
                     /gene="yaaA"
                     /locus_tag="NOB74_001489"
     CDS             14587..14829
                     /gene="yaaA"
                     /locus_tag="NOB74_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HCI1220682.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            14816..15940
                     /gene="recF"
                     /locus_tag="NOB74_001490"
     CDS             14816..15940
                     /gene="recF"
                     /locus_tag="NOB74_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HCI1220683.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            15937..17883
                     /gene="gyrB"
                     /locus_tag="NOB74_001491"
     CDS             15937..17883
                     /gene="gyrB"
                     /locus_tag="NOB74_001491"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HCI1220684.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            17903..20374
                     /gene="gyrA"
                     /locus_tag="NOB74_001492"
     CDS             17903..20374
                     /gene="gyrA"
                     /locus_tag="NOB74_001492"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HCI1220685.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            20610..20909
                     /locus_tag="NOB74_001493"
     CDS             20610..20909
                     /locus_tag="NOB74_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HCI1220686.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            20959..21471
                     /gene="ssb"
                     /locus_tag="NOB74_001494"
     CDS             20959..21471
                     /gene="ssb"
                     /locus_tag="NOB74_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCI1220687.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            21497..21733
                     /locus_tag="NOB74_001495"
     CDS             21497..21733
                     /locus_tag="NOB74_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HCI1220688.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            21876..23849
                     /locus_tag="NOB74_001496"
     CDS             21876..23849
                     /locus_tag="NOB74_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HCI1220689.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            23855..24307
                     /gene="rplI"
                     /locus_tag="NOB74_001497"
     CDS             23855..24307
                     /gene="rplI"
                     /locus_tag="NOB74_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HCI1220690.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            24581..25948
                     /gene="dnaB"
                     /locus_tag="NOB74_001498"
     CDS             24581..25948
                     /gene="dnaB"
                     /locus_tag="NOB74_001498"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCI1220691.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            26728..28020
                     /locus_tag="NOB74_001499"
     CDS             26728..28020
                     /locus_tag="NOB74_001499"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HCI1220692.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         8587 a         5524 c         5609 g         8491 t
ORIGIN      
        1 ttttgtcaca gtcccttact attatttaac tatggataaa caaaatgagg ttctttacta
       61 cccctagata tctagcaaaa tagctgatct ttttgctagt ttatcttctt gggacggata
      121 aacttccaat aatcccgtat tttttcttca agtagtaacg gattgctaaa gcagttgccc
      181 cgataatgat aactactact ggatctaata ctggattgat aactggtggc aatagtgttg
      241 tcgcagaaaa cagtacgacc caaagaagtg tcgttccacc taggataagc aatgtcttac
      301 ccattcctgg tttcttgctt cgatctgctc cgggatattc atattgatag atgtatttgt
      361 acatcatata aaagacccag ccaccgattg cagaacctag aacgagtgta gaaaagccat
      421 aagctggcgt tgttccacgt gaaaacaatc cggtaatcgc aatcatgata cttaatagac
      481 caagcaacag caacgtatta tctaaccaca tcaataaagg ggtggatgaa ttttttactt
      541 ctgctggctt attgatgatt gcttccgttc tttcagagac tgtcccaaac aattgacggg
      601 ctgttcttcc gcctttttgt tctgcaacta aagtaggcag aatgtcatga agggctttta
      661 ctttttcttc ttcagacaaa ttcgctgctt ctaaagattt tttcaaatca aaaatgtact
      721 gttgatttct tttggttaat tttgtttcta aactattgtt ttcttttacg attgctcgta
      781 attgttctgg ttccattatc taatagtcct ccttagccgt tccttttctc aacggtcgtc
      841 acaaaagaca ttctaccata ttctacagct agtttgatag cccttttaca cattaaagcg
      901 gaataacatt acgtcgccgt cttgtacgac ataatctttt ccttctaatc gaacacgtcc
      961 agcttctttt gctgcatgca tgtttccgta atgatccaag tcttcaaaag agacagtttc
     1021 tgcacggata aatccgcgtt cgaaatctga atggatgatt cctgctgctt gtggtgcttt
     1081 gattcctttt ttgaatgtcc aagcacgtac ttcttgttcc ccagcagtaa agtaagtagc
     1141 taagcctaac aaatcataag cagcacggat caactgatcc aaacctgatt cttcgattcc
     1201 taaagcttct aaaaattccg ctttgtcttc ttcatctaat tctgcgattt cttcttctgc
     1261 acgagcactg accacgatca cttctgcatt ttcttctgca gcaaagttgc gcacttcttg
     1321 tacataatga ttcgcgtctg catctgctac gtcatcttct gagacattgg ctacataaag
     1381 aattggtttt gtcgtcaata aaaatagtga tttaacgatt ttttgttctt cttcagtaaa
     1441 ttcgatcgtt cgggcagatt ttccttcttc cagtacaggt ttgattttat ccagtacagc
     1501 tagttctgcc actgcatctt tatctttggt tttagcaact tttgctacac gagtatagcg
     1561 tttgttgata gattctaagt ctgctaacac tagttccaag ttgatcgtat caatatcttc
     1621 tagtggatca acacgtcctt ctacgtgagt aatattatca tcatcaaaac agcgaacaac
     1681 gtgacaaata gcgtctactt ggcggatatg gcttaagaat tgatttccca aaccttctcc
     1741 tttacttgcg ccttttacga ttccagcaat atctgtaaat tcaaaagtcg tcggaacagt
     1801 ttttttcgga tgtacaagtt ctgttaagcg ttgcaaacgc cagtcaggta cttctaccat
     1861 ccctacgttg gggtcgatcg tcgcaaaggg atagtttgct gcttctgctc ctgcttttgt
     1921 gatcgcatta aacaaagttg attttcctac gttgggcaac ccaacaattc cagcagtcaa
     1981 tgccataaat ttattcactc tttctctgca tttttttcaa ttactttttt taatttcttt
     2041 tcaaaatctc gacgggtcat catgacgata tgtccgcaat tcatacatct gattttgata
     2101 tctgcgccca ttcgaatgac ttcccagcga ttcgtctggc aagcgtgagg ttttttcatt
     2161 tcaacgatat cgtgcaagtc gtacataaaa atagcctcct ttttgtttat tcttcatcaa
     2221 attgaatatt caagatatca agaattcgag tcaaatcttt ttgagaaaga tattcaatct
     2281 cgatcttacc tttcccattt ttttcttgga tagctacact tgtaccaaat ttatccatca
     2341 aacgatcttc gctttctcgg atataatatg gtttttcctt tgctagcctt gggatttttt
     2401 tcttttcttt tccatcattt tgatttaact cagaaacaag ctgttccagt tggcggacag
     2461 ttaaattttc agttactgca cgattggcta atttcaagat caatgtttta ttttttaaac
     2521 ctaacagcgt acgggcttgt cccatagata aacgctgatc ttgtaccatt tccttgacaa
     2581 gatccggtaa agaaagcaag cgcaaataat tggcgatata aggtctgctc tttcctaaac
     2641 gactagctac ttctgcttgt gttagtttca ggtttttcat cagcatctca tatgcttctg
     2701 cttcttctaa cggattcaga tcttctcgct gcaagttttc cagcactgct acttgcatca
     2761 tcgcttcttc gtcaaagtct ctaacgatag cagggatcgt ttctttttca gctagtttgg
     2821 acgctcgaaa acgtcgctcc cctgcaataa tctcatatcc ttttactgcg gaacggcgta
     2881 cgatgatggg ttgaaagaca cctgattgtt caatagaatt agctagttcc tgcaaagata
     2941 cttcttcaaa tgttttacgg ggctgatacg gatttggtcg cagctcattc aatggtagct
     3001 ggacaacggt atcatctttt acatccaccg tctctaagtt ttctaaatct tgaaacagtg
     3061 catcgattcc tcggcctaat cctttacttt tcttcacgac ttaccacttc ctttgccaat
     3121 gcttggtaga cttcagctcc tcgagaacgt ggatcgtagt cgatgatcgg ttttccatga
     3181 ctaggtgctt ctgataaacg aatatttctt ggaatgatcg tttcgtaaac tttttcgcgg
     3241 aagtatttac gtacttcttc tacgacttca tttcccagat ttgttcgtgc atcatacatt
     3301 gtcagtaaga ctccctcgat ctctaattct ggattaaagt gtttttggac taaacgaacc
     3361 gtattcagta attggcttaa tccttccaat gcgtaatact cacactgaac aggtatcaaa
     3421 atcgaatcac ttgctgtaaa tgaattgatt gtcagatggc caagagaagg cgggcaatcg
     3481 atcaaaatat aatcatactg actgcttact tctgctaaag atccttttaa tcttgattct
     3541 cttgccatca ttgacgtcaa ttcgatctct gctcctgcta attggagagt cgcaggcaca
     3601 atactcaaat tttcgtgttc agtgatcaaa gttgcctcat caattggcaa ttcattgact
     3661 agaacatcat agatgtctct tgtcacatca ggttttctga tcccgacacc actggtagca
     3721 tttccttgtg catccatatc cactagcaat acttttttgc caaggctagc aagacaagca
     3781 cctagattca ccgtcgtcgt tgttttgccg acgccacctt tttggttcgc aacagatatt
     3841 atttgtgcca tctcttctcc tcctatttga ttggctgctt attaggcagt ccgggctttc
     3901 ttgggtattt ctttggggtt ggtttctttt tttgaataac gatgatatgc cgttgatcag
     3961 agacattcgg caaggtaacc gcctcttctt tgaggaattt accacctaat aaagcaatcg
     4021 cttgttttgc ttctgtcaat tcctcttcac tttttgctgc tttcaatgca taaaaatagc
     4081 cttcttgttt agccaagggc aaacacaatt ccgctaacac attcaaacga gcaaccgcac
     4141 gagcagtgac aaggtcaaat gatgcacgaa agtgaggatt ttgcccaaat gtttctgccc
     4201 ggtcatgata taaggaagca tcgattccta ataatcgggt taactcagat aagaaggtta
     4261 ttcgtttatt cagagaatca acgatcgtta tctgcagttc tggaaaggca atttttaaag
     4321 gtatgctagg aaaccctgcc cccgaaccaa catcgcataa agataaaggt tgcgtaaagt
     4381 ctacttcaaa tgctaatgta agtgaatcgt aaaaatgctt cagatatacg tctttttcat
     4441 ccgtaatagc tgtaaggttc atcttttcgt tccattcgac taatgtccga taataaatag
     4501 cgaattgatt catttgatga tcggtaagct ctatcccttt ttctgccaag gattggcgaa
     4561 attcttctgg tatcataaat attcctttca ttgtgaaaca gcaattgttt cacagattct
     4621 ctccctactt taacgcaaaa tctctagaca tgcaatcctt ccatatggat tcttaaaaat
     4681 ttgaaaagta agaaaagccg atagactttt tctttctagt atgactcata aaatatacac
     4741 agaagagaga actagctttg agcaatttct gcaaaaacta gttctctctt ctatttatta
     4801 ttacgtatta cgctggttca ctgactttcg caatcttccc ttgttcgata tagaccatta
     4861 ggatacttag gtctgcaggg tttacgccac tgattcggct agcttgggca attgtttctg
     4921 gttggatttt ctgcaatttt tgttttgctt ctgttgctaa tccgttgatt gctgcgtagt
     4981 cgatgttttc tggaatcttt ttcgcttcca tgcgttttaa tttttctact ttttccatgg
     5041 cttttttgat gtagccttca tatttgattt ggatttctac ttgttcgatt tcttttcgtg
     5101 tcaattcttc attttctgga ataaaccgta gaagttctgc ataagtaatc tcaggacgtc
     5161 ttaaaaagtc gcttgctagt acaccatctt ttaatggtgc cgcattaatc gttgctaaaa
     5221 agtcttggac ttcttctgtt ggtttgattc gtacattcat caaacgtttg atttcttgtt
     5281 caactgcttc ttttttcttc aaataattct tgtattgatc ttcttttact aagcctacac
     5341 ggtgacccat ttctgttaat cgcaaatctg cattatcatg acgtaaaagc agacggtatt
     5401 cagcacgtga agtcagcaaa cgataaggtt cgttcgttcc ttttgttacc aaatcatcga
     5461 tcatgacacc gatgtaaccg tcacttcgtt tgatcactaa aggttctttt ccctgaactt
     5521 tcaaagctgc attgataccg gcaatcagcc cttgtccagc cgcttcttca taaccgcttg
     5581 taccatttgt ttgtccagct gtataaagat tttcaacgac tttagtttct aatgtcggac
     5641 ggagctggtg tggctctact acgtcatatt cgatagcata tcctgtacgc atcatttcta
     5701 ctttttctaa tccagcaata gaatgaagca tgttgacttg aacatcctct ggtaaagaag
     5761 tagataaacc ttgaacatag acttcttccg tatttaagcc ttctggttcc aaaaataatt
     5821 gatgacgtgg tttgtctgca aaacgcacga tcttatcttc gatggatgga caatagcgag
     5881 cgcctacccc ttcaacgatc cctgtaaaca ttggggcacg atgtaagttg tctcgaataa
     5941 tttggtgagt cgtctcacct gtataggtca gccagcaaga ttcctgatct agtttatagg
     6001 cactatctgg tgtgctgaag ctaaaatgat tcggctcttt gtcaccaggc tgctcttctg
     6061 taacagaata gtcgatcgta cttgatttta ctcgaggcgg tgttcctgtt ttgaaccgtt
     6121 cgatagcaaa gccaagttct tttagatgat tcgctagtcc aatagaaggt tgagagttat
     6181 tcggacctga tgaatatttc aattcaccga taatgatttc tccgcgaagt gctgttccgg
     6241 ctgtaataac aactgctttg gcccggtagc tcgctcctgt ggacgtcact actccatgac
     6301 aaacaccatc ttcgacgatc agttcttcga cgattccttg tcttagcgtc aaatttggtt
     6361 ctttttcgat cgtatgtttc atttctgttg aataagcatg tttgtctgct tgtgctcgca
     6421 atgctcggac agctgggcct tttcctgtgt tcaacatacg catttggata taggttttat
     6481 cgatattctt acccatttct ccgcctaacg catcgatttc tcgaacgaca acgcctttag
     6541 ctggtccgcc tacagaagga ttacatggca tgaatgctac catgtccaaa tttattgtca
     6601 gtaataatgt ttttgatccc atacgtgcag cagcaagtgc agcttctgaa ccggcgtgtc
     6661 ctgcgccaac aacgatcacg tcatacgcat ctgcttcata atgttccaat cgtttgttcc
     6721 tccttttatt ttcctaaaca aaattgactg aataattgag tgattagctc atcttgtaca
     6781 ctgtcgccga caacttctcc tagatagtcc cagcaacgcg tcatatctat ttgaacgaga
     6841 tccacaggca ttcctgaatc aatacctgca atgacttctt caagtgagag ggaagctttt
     6901 tctaacaacg cgatatggcg ggtattagaa acataagtag cgtctctttc tcctgtttct
     6961 ccgctgaaga ataaatcaga aatagctgat tccaaacgat ctagtccgtc gtttttagct
     7021 acggaaattg aaaaaactgg ttcattttcg atcaatttct tcaatttttc ttgttccagc
     7081 tgtgctggca aatctgtttt atttagaaga atgatccgtt tcaatccact tgtcgcttcc
     7141 aataattgtt catcttctgc tgtcagtggt tcgctttggt ttagaacaag taagatcaag
     7201 tctgcttctg ctaatgcttt tcggcttctt tcgaccccga tccgttccac cacatcttct
     7261 gtttcccgaa ttccagctgt atcgattagc ttgagcggta ccccccgaac attgacatac
     7321 tcttcgatta catctcgagt cgttcctgca atatccgtaa cgattgcttt ttcttctctt
     7381 aacaaatggt ttaacaaact tgatttgccg acatttggcc ggccgatgat tgccgtactt
     7441 aacccttccc gcagaacctt cccttgcttg gatgtagcaa gtagcgcttg gattctttgt
     7501 tggatcatct gcgctttttc aagcaataac ttcgtagtca attcttcgac atcatcatat
     7561 tctggataat caatatttac ttctacttgt gctaatgtct ctaaaatctc ttgtctcaat
     7621 gagcggatca aagcagacag attgccgtct aactgattaa gagctagtcc cattgctttg
     7681 tctgtttttg cccgaatcaa atccatcaca gcttctgcct gtgaaaggtc aacacgacca
     7741 ttcaagaatg ctcgttttgt gaattcgcct ggctcagcta atcttgcacc ttctcttaac
     7801 aatagctgca aaatttgatt gactacaacg atcccaccgt gacaattgat ttctactaca
     7861 tcttcccgcg taaatgtctt tggtgctctc atcacggaga ccatgacttc atcgacaagc
     7921 tgattgctct tgggatcaac gatatgtcca taatggatcg tatgacttgg tacttctgat
     7981 aatcgtttgt ttccagattg ataaacttta tctgctagtt gcacagcttg atcgccactt
     8041 aaacgaacga tactgattgc accttctcca ggtggggtag aaattgccgc aatcgtatca
     8101 aattctaaag taatttcagc cattttttca cttccttttt cattttgcgc acaaaaaaag
     8161 tgcccactcc accctttatg cacaataaac ggtgaacttc gcactttgac tgcttgttct
     8221 tgattaaatt ctggtcatag attatcacac ttgctataag gaatcaagtg tttaaaacaa
     8281 ttagatgaag ttgagcctgt tctgcttcca ttaccttata tttaattgtc cttggatgtc
     8341 tctttgcgtt ctttggttta ttcgaagaga agatactgta taaacaaggc tttatctttc
     8401 ttaaaaaaaa cggtacacta aatggtagcg ctatctaaac tatacacttt tgaaaggaga
     8461 aaatatgtga gcccgttcag atctgctgca ttggaagaag aaagtgaccc tcggatcaac
     8521 gatgtcgttt tatctacagg gaatatcaac cagaaatata tcgtccgcga tatcgttttt
     8581 gttgtggaat gcttagaagc tgatttgttt gacccatctt ttcccaaaga tgaccttttc
     8641 ttaacaacga agaggaaatt aaagacgaag gtacttgaat atggtgcgaa tgcagtaatc
     8701 aactgtcatt ttgagtatca gcaaaaaaaa cgcgacggaa agtattttct ggaacttttt
     8761 gcttatggaa cagtgatcca atttatccaa acaacgattg gttaaatgaa acagacaaaa
     8821 aaagcggatc aaaactgaag acagtttcga tccgcttttt tctatcaaag ttagtgacta
     8881 cttcatcgta tactctgata agaatgattt ctagtaaaat atacttggtt tgaaaaactt
     8941 tgtcaacgtg atttattcaa aaagtaatgg aatcaataat attttttagc aggttctact
     9001 actaaataac gataaggttc ctcaccttcc gaatgtgttt ttacatgttc atctttgctt
     9061 aatgcagcat ggatttgttt acgttcaaat gcaggcattg gttctaagaa aacaggctgc
     9121 cctgtccgtt ttactttttc agccgtgcga tcagctaaac gctgaatgat ctcttggcgc
     9181 ttttcacggt aattgcctac attgactact acagacagct tatttcttgc taaacgatgg
     9241 atgaagactt gtgccagata ttgcaatgca ttcagtgttt ttccatgttt cccaatcagt
     9301 atgccttgct tttgtgtttc taaatggaaa acaaccatat tatttgattc tctttccatt
     9361 ttgacaagag ctggagcatc aagctgtttt gaaatttcag taagataaac tgccaattcc
     9421 gttaaagctg cttcatcacc tagctcactt acttcttctg ttttttcttc aagaatcgtt
     9481 tcgttgacta cctcgatctc agctgttggt tcttcttcca aaatttcttc tacagtctgt
     9541 tctactgttt cagaaacttt ttcgctgata cttggctgga tcgaaagccg tgcattcttt
     9601 cgacccattc ctaggaaacc tttttttcct tcttccagta tttcgatttc gacttggtct
     9661 ttggccaaac ccaaatcagc cagacctagt tggacagctt cgtctattgt tgcagcttca
     9721 taaatcggca ttagcattac ctcccctatt atttccgttt tttcttagga ttcattgctt
     9781 tcttaagagc acgttctctt tcgcggattc tccgtgcttc ttcttcacgc tcttttcgaa
     9841 ttttgaaagg gttgttgatc agcagcgttt gtacaacttg gaaggcattg gaaactaccc
     9901 agtataatga aagaccgctg gctaaattga cacccatcac taaaatcatt acaggcatca
     9961 cgaaattcat gatcttcatt gatgcattcg attcaatttg actcatgcta gataaatacg
    10021 tacttgcaaa agtaaagatt gctgctaaaa tcggcaaaat aaatgttgga tccgcgttcc
    10081 ctaagttcaa ccataagaaa tgcccttgtt tcaactctgg tacacgtgaa atagattgcc
    10141 ataacgccat caagattggc atttgtacta ataaaggaag acaaccagca tatggattga
    10201 cgccattttc tgcatataaa cgctgctgct cttctcttaa cttactttgt gtttccggat
    10261 ctcttgaact atattgttgc tgcagtgctt ttaatttcgg ttgtaattct tgcgttttac
    10321 gcatgctctt tgtttggaaa tgcatcaacg gcaataggat cacgcggatg atcagtgtaa
    10381 ataaaatgat ccctatccct gcattaccaa atgacaacgc cttgatcgcc tcagcaaagt
    10441 aataaacaat ataacgatcc caaattcctg tactctgtgc gctgacttcc ccagttccgc
    10501 aaccggataa gacgatgacc aaactaacga taccggccat caaaagtaaa cgtttgtatt
    10561 tcttcactta ctcttttcct ctctgtcgat tatttttgca agttttaaga cgtggactaa
    10621 attggagcga acctcatcat aagtcaaccc cttcacactt ggtctagcaa tcacaataaa
    10681 atccaactcc ggatcaattt cttcttttat agaataaact gctgctcgga tttttcgttt
    10741 gacttcattg cggtttaccg cgttgccgac cttttttcct acagataaac caactcgaaa
    10801 atgaggctgt cccggttttt ccaaacggta aacgacgaat ttgcggttag caaaagaatc
    10861 tcccgtatgg aacacggctt gaaactctcg ttcttttttt actcgatacg cttttctcat
    10921 tagttttctt tccttttcta tctctcactt acgctcataa tcataccata attacgattg
    10981 tcctttcatc atttccctaa aaaagagtat aaaaaaaacc actgaaaccc cagtggccta
    11041 agctgaaaga acttttcttc ctttgcgacg acggctagct aacacacgac gtccattttt
    11101 agtactcata cgtttacgga atccgtgaac tttttgacgt ttacgtttat ttggttggta
    11161 tgttcttttc atatattcca cctccaaaat gttcttatct attttataaa cacagacata
    11221 ctttgatagt ataacgacaa agtagtgatt ttgtcaatat aaaatagaag atcgattgtt
    11281 aaaacttatc cacaagatta tttttttcta tgggagtcct atgtggaaaa agttatgcac
    11341 agggattatc cacagataat aaatggctgg ttttacacag aaaacacacg tgtaaaaaaa
    11401 gtaatccaca atcaggtgat ttcctgtgta ttccgtctcc taactattgg tatatctata
    11461 ttttttatcc acagatgcaa gaggaaatct attgattttt acgagttttc cacctgtgca
    11521 ttagtggtgt ggaaaacttt tttttgacaa ctgtgttttt ctcttttttc tttttgtcga
    11581 ttgtgtggat aattgtaatt aaaaaatttt tttcttcggt ttctgtggaa aactattgaa
    11641 aaaaatgcta aattagtact agttattcac tttttaatga aggaggaggc cttatatggt
    11701 atccctcgat gctttatgga atgaattaaa agcaacatac caaaaggatt tatcgcctgc
    11761 tagctataat acatggatcg aaacagcgaa ccctcgaacc cttgatcaaa accagctcgt
    11821 tgttgaggtt cctagcaaga ttcataaaga atattgggaa aaaaacctgg cgacaaaaat
    11881 cgttgaagtc ggttatatgt tatcaggaaa tgagattatc cctcgcttta ttactggcga
    11941 agaagcagag caagaagaag ttatagaaga aaaaaatcca aaagttgtgg cacctagtcc
    12001 gctaaaaaaa gccatgctga accctaaata tacctttgat acgtttgtca ttggtaaagg
    12061 aaaccagatg gctcatgcag cagcgctcgt tgtagcagaa gatccaggtt ctatttataa
    12121 cccgctcttc ttttatggag gcgtgggact tggtaagact cacttgatgc atgcaattgg
    12181 tcatcaaatg ctgcaaagtc agcctaatgc caaagtaaaa tatgtaagca gtgaaacttt
    12241 tgctaatgat ttcatcaatt cgatccaaaa caaaacagca gaagagttcc gtcaagaata
    12301 tcgaaatgtt gatttactgc tagtggatga cattcaattt tttgcagaaa aagaagctac
    12361 gcaagaagag tttttccata ctttcaatgc cttgtacaat gaagggaaac aaatcgtact
    12421 aaccagtgat cggttgccaa acgagattcc gaaactgcaa gaacgcctcg tttctcgctt
    12481 tgcatggggg ctgtctgttg atattacacc gccggatctt gaaacaagaa cagcgatttt
    12541 acgtaaaaaa gcggcggctg aacgtctaga gatcccagat gacacactaa gctacatcgc
    12601 aggacaaatt gattctaaca ttcgtgaatt agaaggtgcg cttgttcgag tgcaagcttt
    12661 tgctgcgatg aatagtgaag atatttcgac tagtctagct gcagacgcac tgaaaacgtt
    12721 aaaatcagga aaaggacatc ctcaattgtc aatcctgcag atccaagaag aagtggcaaa
    12781 gtattatcac atccaattga aagatatcaa aggaaagaaa cgcgtcaaat ctattgttgt
    12841 tcctagacaa atcgctatgt atttggcacg tgagctcaca gataattctt taccgaaaat
    12901 cggagctgaa ttcggtggca aggatcatac aacggttatc catgctcatg aaaaaatcca
    12961 gcagctgatg gattctagtg tcagtatgca aaatgaagta tcagaaatca aaaacttttt
    13021 actaaattaa tttgtcgatt ctatcaactg aaaatagcat gtggataaaa gaaaaaaacg
    13081 ttcaaaagtt atgcacactt tttccacagc tgttttttcg tttctctctt acgttttttg
    13141 agttttccac agaatcaaca tgccctatta cttttattat tctttttaac taataataaa
    13201 taaacaaaca ttcaaaggag atacatcatg aaagttactt taaaccgagc tagctttatg
    13261 caggaattgc aaactgttca acgagctatt tcaagcaaaa ccacgatccc tattttgaca
    13321 ggtgtaaaaa tcacactgac acaagaaggt ttgactttga cggggagcaa cgctgatata
    13381 tcaattgaaa cttttttgtc tgttgaaaac gaaaaagcaa atatgcaaat cgaatctact
    13441 ggttccattg ttttacaagc acgtttcttt agcgaaatca ttcggagact tcctgaagaa
    13501 acatttactt tagaagtttt agaaaataaa caagtagcga ttacttctgg aaaagcgaat
    13561 tttatcgtaa atggattaga tgcagataac tatcctcatc ttcctgttgt cgaaagccat
    13621 aaccagatga aattacctgt acacgtattg actaaactaa tcaacgaaac agtttttgct
    13681 gtctcacaac atgagagtcg tccaatcttg acaggtgtgc atttcatttt atctgataat
    13741 tctttattgg ctgtagctac tgattctcac cgtctaagtc aacgcgtgat tccagtagaa
    13801 caagcggctg atcattttga tattgttatt cctggaaaaa gtttgatcga attatctcgc
    13861 tcattaacaa atgaagaaga aatcgtcgaa atcagcatta tggaaaacca agtgttgttc
    13921 aaaacagaaa cgatgtattt ctattcccgt ttgctagaag gaaactatcc tgataccaat
    13981 cgtttgattc cttcaagttt taatacagag gttgaatttt ctgttcctag ctttttagcg
    14041 gcgatcgaac gggcttcttt actttctcat gaaggccgta acaacatcgt tcgtttatct
    14101 attcgtccag atgcggttgt tttatacgga aattcgccag aaatcgggaa agtagaagaa
    14161 agcttgagtt atacagcaag cagtggcgat ccattagata tttctttcaa tccggattat
    14221 atgaaagcag cgttgcgtgc atttggagat atgagcatca aagtgaaatt tatctctgct
    14281 attcgtccat ttacattgga accaacggaa gatggcgttc aatttattca gctgattact
    14341 cctgtacgta caaattaaca atgattttca ttgttcttga aaatttaatt gaaaagaaat
    14401 agaaaaaata aaattttaaa cagaaggccc taaaatctct tttaaggctt tctgtttatt
    14461 tttgtttaaa tcaccttttt tagattaaat cgtcttatat ggaaaaatat atggataaat
    14521 ttgttttatt gcgaaaaaaa aggtataata gagtatactt ttaataatga aaatgaggga
    14581 tgggcattga aacaacaagt cattctaaat acggaattca tgacgttggg ccaaatgttg
    14641 aaagaagtca cagttatcgg tagtggcgga caagcaaaat ggtatttggc agaaaacact
    14701 gtgttagtcg atggcgaacc agaaaatcgt cgtggacgca aactttatcc cggcatgatg
    14761 gttgaagttc cagaagtagg aacttttttt atggtaaaaa aaggaaacga cgataatgag
    14821 gctgaataag ctgtatttaa aaaattatcg aaattacgaa gagctgaaca tcgaattttc
    14881 caagaacctc gtcatctttt taggagaaaa tgcgcaagga aaaacgaatc ttttggaaag
    14941 tatctacgta ttagctatga cgcgaagtca tcggacaagt agtgagcagg aattgattgg
    15001 ctggactgac gatcaggcga tgattcaagg agagatcaca aaaggttcat ccactcttcc
    15061 attagaaatc ttattatcta aaaaaggccg aaaaaccaag atcaaccata tcgaacaaaa
    15121 aaagttaagt acttacgtgg gacaaatgaa tgtcatttta tttgcaccag aagatctttc
    15181 tttagtaaaa ggcagcccgc agatcaggcg gaagttttta gatatggaat taggccagat
    15241 caatccaatc tatctttatg atcttgtcca ataccaagca attttgaaac aaagaaacca
    15301 gtatttaaag caattgaatg aaaaaaaaca aactgatttg ctttatttgg atattttgtc
    15361 cgaacaacta gcagcgtttg gcagcaaagt attgaaagca agagcacagt tcgtcaagcg
    15421 attggagttt tgggctaatt ctttgcatca gcaaatcacc catcaaaaag agcagctgga
    15481 aatcgagtat ctcaccgcag tcgattcttt agaaacacat acgcaagagc aaatccaaga
    15541 acaatttctc gcacttttga accaaaataa aaagaaagac ctttttcggg gaacaacgac
    15601 agttggtcct catcgtgacg atctttcctt ttttattaat cagaaaaatg tgcagactta
    15661 tggatcgcaa ggacagcaaa gaacaactgc actaagtgtc aaattagcag aaatcgattt
    15721 gattaaagaa gagacggggg aatatccaat ccttttgtta gatgatgtga tgagcgagct
    15781 ggatgatagt cgtcaactcc atctgctaga aacaatcgaa ggaaaagttc aaacgttctt
    15841 aacaacaacg acacttgacc atgtaaaaaa taaaatgact gttgaacctg agatttttta
    15901 tgttcaacaa gggaaactaa aaggagaaga aactgaatga cagaagaaag aagtttagta
    15961 gaacgcgcta aagagtatga tgccagtcag attcaagtac ttgaaggact tgaagccgtt
    16021 cgtaaacgac ctggcatgta tatcggttcg actagttctg agggtctgca tcaccttgtt
    16081 tgggaaattg tcgataattc gatcgatgaa gtattagcag gttttgcaac gaaaatccat
    16141 gtgattattg aaaaagacaa cagtatcacc gttattgacg acggtcgggg gatacctgta
    16201 gatatccagg caaaaactgg acgtcctgca gttgaaacgg tctttactgt tttacatgct
    16261 ggaggaaaat tcggcggtgg tgggtacaaa gtttctggtg gacttcacgg agtaggatct
    16321 tctgttgtta acgcgctttc tacacagctt gatgtcaaag tatacaaaga aggaaatgtg
    16381 tactatcaag aatatcgtcg tggagctgta gtggacgact taaagattat cgaacaaacg
    16441 gatcgccatg gaacaacggt tcactttacg ccagaccctg aaatttttac agagacaact
    16501 gagtttgatt tttcaaaatt ggctacccgg atccgtgaac ttgctttctt gaaccgcggg
    16561 atgcgtatat cgattgaaga caaacgagaa gaagaaccag tcatcaatga ataccattat
    16621 gacggcggga ttaaaagtta tgtcgaatac ttgaatgcaa acaaaaccgt gatttttcca
    16681 gaacctgtat atttggaagg tgaacagcaa gatatcgcag ttgaagtctc tatgcaatat
    16741 acagacggct accattccaa tatcatgagt tttgccaaca atatccatac gtatgaaggc
    16801 ggaacacatg aatcaggatt caagactgct ttaactcgtg tgataaatga ttatgcccga
    16861 aaacaaaagc tgatgaaaga aaatgacgac aacttgaccg gtgaagacgt gcgagaagga
    16921 ttgacagctg ttatttctat caagcatcct gaccctcaat tcgaaggaca aacaaaaaca
    16981 aaattgggca attccgaagt acggacagtc actgatcggt tatttagcga acatttcatg
    17041 aaattcttgc tggaaaaccc aagtgtgggc cgtcaaattg ttgaaaaagg attactagct
    17101 tccagagctc gtctagcagc gaaacgtgcg cgtgaagtaa cgagacgtaa aggtgcttta
    17161 gagattagta atctgccagg aaaattagcg gactgctcta gcaacgatcc tgaaaaatgc
    17221 gaattgttca tcgtcgaagg agattcggcc ggcggatcag ctaagcaagg tcgtaatcga
    17281 gagtttcaag ccatcttgcc tattcgtggg aaaatcttga atgttgaaaa agcaagcatg
    17341 gacaagatct tggcaaatga agagatccgg tctttattta ctgctatggg tacagggttt
    17401 ggagaagatt ttgatgtatc gaaagctcgc taccacaaat tagttatcat gactgatgcc
    17461 gatgtcgacg gcgcgcatat ccgtacattg ctgctgactc ttttttatcg ttacatgcgt
    17521 cctattgttg aagctggata cgtctatatt gctcagccac ctttatacgg ggtaaaacaa
    17581 gggaagaata ttacgtatgt acaaccagga aaaaatgcag aagaagagtt gaaacaagtc
    17641 gttgcttcac ttcctgcctc accaaaacca agcgttcagc gttataaagg acttggagaa
    17701 atggatgatc atcaactatg ggaaacaact atggacccaa gcaatcggat gatggcccgc
    17761 gtcagtgtgg acgatgctat tgcagcagat cagatatttg aaatgttgat gggggatcga
    17821 gtagaacccc gtcgtgcatt catcgaggaa aatgcacact atgtgaagaa cttagatatt
    17881 taatcatgaa ggaggaaaaa gaatgagtga agaaatcaga gaaaacatcc atgatgtcaa
    17941 tctaaccagc gaaatgaaag actccttcat cgattatgcg atgagtgtta ttgtcgcacg
    18001 tgcacttcct gatgtcagag atggtctgaa acccgttcat cgccgtattt tatacggcat
    18061 gaacgaatta ggtgtaacac cggataaagc ccataaaaaa tctgccagaa tcgtcggaga
    18121 tgtcatgggt aaataccatc ctcatggaga ctatgcgatc tatgagtcaa tggtacggat
    18181 ggcacagcca ttcagctacc gttatatgct agtggatggt catggaaact ttggttctgt
    18241 tgacggtgac ggtgccgccg ctatgcgtta taccgaagca cggatgagca aaatcgctac
    18301 agaaatgctg cgtgatatca ataagaacac tgttgatttc caaagcaact atgatgatac
    18361 agaaaaagaa ccagttgtac tacctgctcg cttcccgaat cttttagtga acggaacaac
    18421 ggggatcgcc gtaggtatgg ccacgaatat cccacctcat aacttgtctg aggtagtagc
    18481 ggctatcgat ttgctgatgg ataatcctga tgtgacgacc aatgaattga tggaagtatt
    18541 acctggacca gattttccaa caggtggttt ggttatggga aaatcaggaa tccgaagagc
    18601 gtatgaaaca ggtaagggtt ctattaccgt acgtgcaaaa gttgagatta ctgagatgcc
    18661 aaatggtaaa gaacggatca tcgtgacaga attgccttat atggtcaata aagcaaaatt
    18721 gatcgaacgg atttctgaac tgcacagaga caagcgtatc gaagggatca cagatttgcg
    18781 ggacgaatct tcccgtgaag gtatgcggat cgtcattgac atccgtcgtg acgccagcgc
    18841 atctgttatc ttgaataact tatataaatt gacatccttg caaaattcat ttggattcaa
    18901 tatgttggcg atcgaaaaag gtgtgccgaa agttttgagc ttgaaacaaa ttcttgaaaa
    18961 ctatatcgaa catcagcgcg aagtcatcac aagacggaca gtctttgaaa aagaaaaagc
    19021 agaagcaagg gcacacattt tagaaggttt gcgtattgct ttggatcata tcgatgaaat
    19081 cattgcgatt atccgcgggt ctaaatcaga tgacgaagca aaagcgacga tgatcgaacg
    19141 gttcgattta tccgatcgcc agtctcaagc tattttagat atgcgtttac gccgattgac
    19201 cggtttggaa cgggaaaaaa tcgaaaatga ataccaagaa ctcttaaaac tgattgaaga
    19261 tttaactgac attctggcaa gaccagaacg tgttacagaa atcatcaaga atgaattagc
    19321 agacttgaat caacgatttg gtgataaacg acgcacagaa ttactagtcg gtgaggtctt
    19381 aagtctggaa gatgaagatt taatcgaaga agaagaaatc gttattacat tgacaaacaa
    19441 tggttacatc aaacgtttgg caaataatga attcagagct caacgaaggg gtggacgtgg
    19501 tgtccaagga atgggtatcc acaatgacga cttcgtcaaa aatctggttt cttgttctac
    19561 ccatgataca ttgttattct ttacgaataa cggaaaagtg tatcgggcaa aaggatacga
    19621 aattccagaa tacgggcgca cagccaaagg aataccaatt atcaatttac taggtatcga
    19681 ttcgagtgaa agcatccagg caatcattgc ggtgacggga gaagcagaag aaggccacta
    19741 tctcttcttt acgacgcgtc aaggtacagt aaaacgtact tctgtcactg cttttgctaa
    19801 catccgaagt aatggtctga tcgcaattgg tttgaaagaa gacgatgagc tcgtcaatgt
    19861 gctactgaca gatggtcaat ctaatatcat tattggaaca cataacggct actctgtcac
    19921 tttcaaagaa gaagcagtcc gcgatatggg acgtacagct tccggggtta gaggaatacg
    19981 cctgcgtgag gaagattatg tcgttggggc agccttaatg aaggaagatc aagaagtatt
    20041 agtgatcaca gaaaaaggtt acggaaaacg gacaaaagta tcggaatatc cagtgaaagg
    20101 ccgcggaggt aaagggatca aaacggcgaa catcactgaa aaaaatggtc cactagctgg
    20161 attgaccact gtttctggag atgaagacat catgctgatt acagataaag gtgtcattat
    20221 ccgtttcaac gtatcgactg tttctcaaac tggacgttca acattaggcg tacgtttgat
    20281 gaagatggaa gctgatacga aagttgtcac gatggcagca gtcgaaccag aagctgcaga
    20341 acaaacagtt gaagaacaag gatcagaaga atagccatca agactaattg tgtaagctag
    20401 caagaatgac cgattaaaaa atctggttat tcctgctggc ttttttgatt agttgaattt
    20461 ctcttaaaat attcgaaact gttcattctg tattgctttt gaccaaaata gagtgtataa
    20521 tcagagcttg tgagtagtct aattaattag ataactctcc ttgctcttag gaacctaaga
    20581 gccgaaagtc cacagggagg tgaatatcaa tggaaaacac gaaatatgaa atcatgtaca
    20641 ttattcgtcc aaacattgat gaagaagcaa aaactgcttt aatcgaacgt ttcgatgcaa
    20701 tcttgaaaga taacggagca gaagttatcg aatcaaaaga ttgggaaaaa cgccgtttcg
    20761 cttatgaaat gaacggttac cgtgaaggta tctatcacat cgttaaagta tcttctccat
    20821 catcagcaaa tgctgtcaat gaatttgacc gtcttgctaa aatcaacgac gatatcattc
    20881 gtcacatgat tgttaaagaa gaagcttaat tgttgtttca tgtgaaacaa tagaaaacga
    20941 tgagaggaga tgactatttt gattaataat gttgtattag ttggacgtct gacgaaagat
    21001 ccagatttgc gttacacagc aagtggtacg gcagtcgcaa catttacttt ggctgtgaat
    21061 cgtaatttta caaaccaaag cggcaatcgc gaggctgatt ttatcaactg tgtgatttgg
    21121 cgcaaatcag cagaaacttt agcaaactat gctcgtaaag gaacactttt aggtgttact
    21181 ggacgtatcc aaactcgttc ttatgataat cagcaaggac aacgtgtata cgtgacagaa
    21241 gtagtagctg acaacttcca attgctggaa agtcgttctg catctgaaaa tcgccaacaa
    21301 agcggcggat tccaaagttc tggtcaatca gctggcggat ttggcggaaa caataactct
    21361 aatcaaacat ctcaatcatc caacggtatg cctgatttcg accgtgatac ttctgaccca
    21421 ttcggctcaa gttcaacgat cgacatttca gacgatgatt taccattcta aacgaatttg
    21481 ataggaggga aatagaatgg cacaacaaag aagaggcgga cgtaaacgtc gtaaagtaga
    21541 ctacattgct gctaaccata ttgaatatat cgattataaa gatatcgaat tactaaaaag
    21601 atttatttca gaacgcggta aaatcttgcc acgtcgtgta actggtacag gcgctaaaaa
    21661 ccaacgtaaa attactgttg caatcaaacg cgctcgtatc atgggcttgc tacctttcgt
    21721 tagcgaagac taataaatcc taggaattga atgactgatc cttttgatca gctattcaat
    21781 tccttttttt ctgtaaaaat aacctctatt cgtttagtcg ctcgaatgac gaaagttatg
    21841 gtaaaatcaa attagtcata tatgggagga aaattatgga aaataaaaac aatcatttat
    21901 ccccgaaacc tctcttcctt atcctgttta tattaatcga agtattggta gtcttaattt
    21961 taccatttcg ttttgttagc gcttcggtca ttctattgat gaatttatgg ggtgttcgct
    22021 attggttgaa aatgaaacgt tggcttattt taaataaacg tgaaaaaatc cagcaggctt
    22081 cgactgtagc tgaaaccaat ctagcttatg tctcagaagt catgcctgta ggagtgattg
    22141 cttatcagcc atcaagccaa aaaatcgaat ggctcaatcc attagcattg aaaatcaaag
    22201 atcaaagtgg attaacagag gaagaattgc tagatacttt ttttactgca aaagaaaaaa
    22261 agaaaaacca agtctatcta gcagataaaa catttcagtt tgatatggat acagtaaagg
    22321 gtgttgttta ttttaatgat attacccaaa accagttgtt aaaactccat cagacgaaca
    22381 gtcagccggt gattggtatt ttatctattg ataactatgc agatgccatt gataaattgg
    22441 atgacaaaga gatttcttat ttgaactctt tcgtcactac actagtttct gactggatga
    22501 atgaatacca tgtctttttc aaaagaatca acgcagaacg gtttttcttc gtagcacaga
    22561 tgatcgatct gaaaaagatg atggataaaa aatttgattt gctggatcgc tttcgagcag
    22621 aagctgaaaa acagagctcg cctatcaccc ttagtatggg gattgcttat ggctcaagaa
    22681 ccctcgatga aatcggtgga gaagctcaga ataatttaga tgttgcttta gtccgtggag
    22741 gcgaccaagt tgtcgtgaaa gaggtaaaag aaggagcaaa acctgtttat tatgggggga
    22801 aatctgctaa gaatgtcaaa cgcacgcgtg ttcgttctcg agcgatgagt accgctttgc
    22861 gtcggatttt tgatgaaaca ggcgatgtgt ttatcatggg gcacaagttt ccggatatgg
    22921 atgctttagg ctctgctttt ggtgtcagtt gtctggcacg cttcaaccag aaaaaagctt
    22981 acatcgttat caacgagaac gagatcattc cagatgtaga acggtgtctt gaagaaatcc
    23041 ataagcatcc tgaattagaa atgcaactaa tctctccaga acgtgccata gagctgaaaa
    23101 aagaagagga cctcctcgtg atggtggatt accataaacc ttctctatcg atctctcagg
    23161 gcctatatga gcaatttgat aagattgtga tcattgatca ccatcgtcgt ggggaagagt
    23221 ttccaagtaa acctctgctg acttatatcg aatcttcagc ttcttcagct tcagagctag
    23281 tttctgagct gatccaatac caaagcagca aaacaaatcg cttagatcgt tttgaggcca
    23341 cattattgct tgcagggatg gttgtagata caaatagttt caatgtccgt acaactgcac
    23401 gaacttttga cgttgccagc tatttaaggt cttgtggagc agacgcatcc ttagtacaat
    23461 atttattgag ctcggattta gcgacatact tggagatcag caatttgatt gctggaagcg
    23521 actatgtgac ttctgatatt gttgtggcgg cagggacaga cgaaaaagag tataatagtg
    23581 ttatagcagc aaaaacagca gatacattgc tttcgatgat caatatcaat gcagctttcg
    23641 tcattacaaa gcggacagac ggcttgattg ggatcagtgc cagaagtacc ggcacgatca
    23701 acgtccaaat catcatggaa tccttaggtg gcggaggaca cttcacaaac gcagctactc
    23761 aactggaaaa tacgacagtt gaggaaacaa aacagaagct atttgctgca atcaaagaaa
    23821 atatgaatca aatatatgat aaggagtaat ccaaatgaaa gtaatttttt tacaagatgt
    23881 aaaaggaaaa ggtaaaaaag gggacatcaa agaagttcca gcaggttatg cacaaaatta
    23941 tctaatcaaa aataacttgg caaaagaagc aacgaaaagc agtatcagtc agttagcagg
    24001 acaaaagaaa gcacaagaaa aacacgaagc tgaaatcttg gaagaagcta aaaagttaaa
    24061 agaattcttg gaaaaagaag atactgtagt cgaattgaag gcgaaagcag gggaagacag
    24121 ccgtttgttt ggttcgatcc cttcaaaaca aattgctgaa gggttaaaca aacaatacaa
    24181 aatcaaatta gataaacgaa aaatcgaatt agaaaatccg atccgttcac taggctacac
    24241 aaacgtacct gttaagcttc atcatgaggt gacggctacg atcaaagttc atgtcgtaca
    24301 agaataacaa atcttgatag cgatgttcag ctggtaagta taaccagaag gaaaaaagac
    24361 aaaccgaaat ttatctgaga aaacagctgc agcaatgaaa gcaaaagctg caaatcgatt
    24421 tcagattgat ttcggtttct tttttgggaa cagcaaaata gcataaagaa aacgagtata
    24481 ataaaagaga actatttttt tattacactt tcggtacgaa tgatgacttt tctctcattt
    24541 tcttgtaaaa tgaagcaatt gaagacaagg agcgatacgt atgaatgaag tgtggcagga
    24601 tcgaatccca ccgcaaaata ttgaagctga acaagcggtt ttaggctctg tttttcttga
    24661 cgcagaaacg atcattgatg ccatggagta catagagcca aaagactttt atcgtcgtgg
    24721 ccatcaaatt atttttgaga caatgatcga gttaaatgat cgtaatgaag cgattgacgt
    24781 ggttactgtc aaagaccggc tggaacaagc caatttgtta gaagatgccg gtggtttaag
    24841 ttatctctca gacttggcat tagcagttcc gacagcagca aatatcgtct actatgcgaa
    24901 aatcgttgaa gaaaaatcat tgctgcgtac attgatccag acagcaacag gaatcgttac
    24961 gaaaggattc gagcaaggag aagaagttca aacaatttta gatgatgccg aacgcagtat
    25021 cttggaggtt tcggaaaaaa gaaatcgaag cggcttttta tctattgctg aagtactgaa
    25081 ctccacgatt gaaaatatcg atcgactagc tcaaaacaat gaagaaatca caggtctacc
    25141 aactggctat caaggtctgg ataaaatgac agcaggtttc cagcccgaag aactaatcat
    25201 tcttgctgca cgtccagcgg taggtaaaac agcgtttgca ttgaatattg ctcaaaatgt
    25261 aggaacaaaa acagatcgtt ctgttgcgat atttagtttg gaaatggggg cagaatctct
    25321 tgtaaatcgg atgctttgtg cagaaggttc gattgaggcc agccatttac gtacaggtca
    25381 gctttcggaa gaagaatggt cgaatctgat cgttgcgatg gggagtcttt ctcgagcaaa
    25441 tatttttatc gatgatacac cagggatcaa aatctctgaa atccgtgcga aatgtcggaa
    25501 actagcgcaa gaaaaaggca atctaggctt gatattgatc gattatttgc agttgattga
    25561 aggtaacggt aaagagaacc gtcaacaaga agtatcagat atctctcgcc aactgaaaaa
    25621 actggcgaaa gagctgaaag tacctgtcat tgctctttca cagttatctc gtggagtaga
    25681 acagcgacaa gacaaacgac cagtgctaag tgatattcgt gaatccggat caattgaaca
    25741 agatgcggac atcgtagcct tcttgtatcg agatgattat tatgaaagag aaggcggaga
    25801 tgacgatgat ggaaacgagc caaaaaatga caacgtcatc gaagtcatca tcgagaagaa
    25861 ccgaagcggt gcacgaggaa cagttgaact actgtttatc aaagaataca ataagttttc
    25921 gtcgctttcg ccaagagaag aattttaaag aagaggttgt gagccttgag caatcccgag
    25981 agctctcgta agaagatgca aggagtaacc gcaggaacga ctagagtact taatttaaac
    26041 agatctccaa agggattgtg acaaaagtct tgtcacagtc cctttttccg aataaacggt
    26101 gttcaatcag ctgacccttg gtattagctc agcaaacgtc aaaatatgag gaactatttt
    26161 gacgtttgtt tctctaatac tcaggtcaaa acgctgatct tacgacctct tttccttaaa
    26221 cggtgttctc ctgccaactc ctcggtcaca agtcacaata tcatcaaaca tgagaagcag
    26281 ttttttgaaa ttgctccttg tgactcagag ttaaacggca ggctcacaac ctctttctta
    26341 aacggtgttc aaaagcttgc atctgcggta atacgcccaa tcaaacgaaa aatatgagaa
    26401 gctatttttg tttggctgtt cttattactt gatgcaggac agctttttca caacctctga
    26461 ttcacggtgt tccaaaagta gcttcttcga aaaataagtc gaaatttcac aaaaatttga
    26521 gaagcaattt tcgtacattc cttcttattt cttgaagctg accacttctg ttacaacctc
    26581 ttttttaata accattctaa aaagataaag ttcgtttttt aagcgttttt ataaaataaa
    26641 aataaaaatc attcgatttt atttgaaata tgtatctatt attgatacaa tggttcagga
    26701 ttaaataata tagaacgagg tgttcacatg tcatctgtag tagtagtagg tacgcaatgg
    26761 ggcgatgaag ggaaaggaaa aatcacagac tttctcagtg aaaatgctga agtgattgca
    26821 cggtaccaag gtggcgacaa tgcagggcac acaattaagt ttaacggtgt gacttataaa
    26881 ctgcatttga ttccttctgg gattttttat aaagacaaga tcagtgtgat cggaaacggc
    26941 gttgtagtca atcctaaatc attggttaaa gaattagctt atttacatga aaaaggtgta
    27001 gaaacaagta atttgcgtat ttctgaccgc gcgcacgtaa tcttgcctta tcatatcaaa
    27061 ttggaccaat tacaagaaga tgctaagggc gaaaataaga ttggtacaac gattaaagga
    27121 atcggacctg cctatatgga taaagcagct cgtgtaggta tccgtattgc agacttatta
    27181 gataaagaaa tttttgaaga acgtcttcgt ttgaatctag atgacaaaaa ccgtcaattt
    27241 gtaaaaatgt ttgattcaga accacttgat tttgacgata tttttgaaga atattatgaa
    27301 tacggacaac aaatcaaaca atacgtcaca gatacttccg ttatcttgaa tgatgctttg
    27361 gatgcaggca aacgcgtgtt gtttgaaggc gcacaaggtg taatgctgga tatcgaccag
    27421 ggaacttatc cttttgttac ttcttctaac ccagtagccg gtggggtaac aatcggaagc
    27481 ggtgtagggc cttcaaaaat caataaagtt gtcggcgtct gcaaagccta tacgtcacgt
    27541 gtcggtgatg gaccatttcc aactgaatta tttgatgaaa caggagaaca aatccgcgaa
    27601 gtaggacgag aatacggtac gacaactggt cgtccgcgtc gtgtaggctg gtttgattct
    27661 gtagttatgc gccattctaa acgagtttca ggtattacca acctatcttt aaactcgatc
    27721 gatgtattaa gtggattgga aacagtaaaa atttgtacgg cttatgaatt agatggcgaa
    27781 ctaatctacc actatccagc aagcttgaaa gagttgaacc gctgcaaacc aatctatgaa
    27841 gaattgccag gctggtcaga agacattaca ggatgcaaaa cacttgcaga actgccagaa
    27901 aacgcacgta actatgtacg tcgtatctca gagcttgttg gtgtacgtat ctcaacattt
    27961 tctgtcggac ctgatagaac acaaacaaac atcttagaaa gcgtctgggc gcaaatctaa
    28021 ggataaaaac gacgactgaa tcaggacgtt cttaccagag cgagtcgaag tgtttatcta
    28081 tacgataata ataacttgaa gaggtagtga aagagacgtt tagccttatt gccgataggc
    28141 tgtctcttga acactgttta ttcagaataa gggactgtga caaaaaccgt gtcacagtcc
    28201 ctttttccga a
//
LOCUS       DAIGWC010000034        27663 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.034, whole genome shotgun sequence.
ACCESSION   DAIGWC010000034 DAIGWC010000000
VERSION     DAIGWC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.034"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            133..3660
                     /locus_tag="NOB74_001500"
     CDS             133..3660
                     /locus_tag="NOB74_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HCI1220693.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRKENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="NOB74_001501"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="NOB74_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HCI1220694.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="NOB74_001502"
     CDS             7448..7789
                     /locus_tag="NOB74_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1220695.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="NOB74_001503"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="NOB74_001503"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HCI1220696.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="NOB74_001504"
     CDS             9146..11566
                     /locus_tag="NOB74_001504"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HCI1220697.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="NOB74_001505"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="NOB74_001505"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCI1220698.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="NOB74_001506"
     CDS             13000..13737
                     /locus_tag="NOB74_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI1220699.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="NOB74_001507"
     CDS             13751..14566
                     /locus_tag="NOB74_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCI1220700.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="NOB74_001508"
     CDS             14579..15226
                     /locus_tag="NOB74_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI1220701.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="NOB74_001509"
     CDS             15242..15898
                     /locus_tag="NOB74_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI1220702.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="NOB74_001510"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="NOB74_001510"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HCI1220703.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="NOB74_001511"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="NOB74_001511"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HCI1220704.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="NOB74_001512"
     CDS             18240..18758
                     /locus_tag="NOB74_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI1220705.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="NOB74_001513"
     CDS             18865..19365
                     /locus_tag="NOB74_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI1220706.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="NOB74_001514"
     CDS             complement(19645..20565)
                     /locus_tag="NOB74_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCI1220707.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="NOB74_001515"
     CDS             20730..21743
                     /locus_tag="NOB74_001515"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HCI1220708.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="NOB74_001516"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="NOB74_001516"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HCI1220709.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="NOB74_001517"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="NOB74_001517"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCI1220710.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="NOB74_001518"
     CDS             complement(23383..24144)
                     /locus_tag="NOB74_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI1220711.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="NOB74_001519"
     CDS             24333..25427
                     /locus_tag="NOB74_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI1220712.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25513..26472)
                     /locus_tag="NOB74_001520"
     CDS             complement(25513..26472)
                     /locus_tag="NOB74_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HCI1220713.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            26658..27593
                     /locus_tag="NOB74_001521"
     CDS             26658..27593
                     /locus_tag="NOB74_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1220714.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         9129 a         4786 c         5823 g         7925 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtaagga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 ggttatgatt tgtcaaatta agctagaata aaatgcttct tgtacatagc tcaaaaatat
    25561 ttcgattggt gttctgtaat tcaatgattt tcttggaata tgattacgtt gattgctgac
    25621 actggaaata aatgtctgat tcacttttct aaaatccatt gatttcggca gtccattacg
    25681 acgcagaatc ccgttagaat tctcgtttaa tgggcgttga gaaggtgttc cagggtccgc
    25741 aaaatatata tcaatatcat gttggttact aatggctttc cagttagaaa attcttttcc
    25801 acagtcaaac gtaatagatt taaagaagtt tttagggaag cgagaaaacc attgattaag
    25861 ggcagtttca atatctaatg ccttacggcc gttgggttta atcgtgataa tgactttaga
    25921 taatctttca actaaagtaa tgacggcact tttatgatga atgccaacga tcgtatcacc
    25981 ttcaaggtga ccaaactcag aattgaaatc aggataatta tcaggtcgat catggattga
    26041 gcgctgatac tgttgttttc cccgtttttc ctgatggcca ttgggttttc ttttaccttt
    26101 catcggtagt gtgtcaatat caaatattcc tttagaaaat aaacgataaa gtgttctcat
    26161 accgcatgaa acagaccttt cttttcgccc gataatgacg tcaggcgtcc aaccaagagt
    26221 gactttctct ttaatgtaat ctacttcatg agcaggtaat tgaatgactt ttctaccaca
    26281 ttttttctta ttttctttat actggtgcca ataatcaaga gcagtcttgc cttgcttgaa
    26341 cttattgact acattataaa tagtttgtat agcacgtccc attcggttag cgatttcaac
    26401 cggcttatta tgttgaagat aatatgattc tatcattgtc agttcgtcta tggtaagatg
    26461 tttgtaggtc atttatggtt acactccttt gttttctttc gtcggaaata caatttgagt
    26521 gtaccataaa tgccttttta tttttctaac ttaattttac aattcgcggg ttataaaaat
    26581 gaacattgca tagtagagat tctttgatta tactaattca aggttatatg aaaaaagaga
    26641 aatgagatgg atgatttatg aaactttgga tgaaaatcct tttaggcgtc gctttagctc
    26701 tgattgttgc gttagtgttt gcagggaatt atttttataa ttatgctgtt gtgccttctg
    26761 agaaagactt tttagacgaa gatacacctg gtacaacaca gacatccaaa gaaacggatg
    26821 cacataaatg gtttagttca aaagaaaacc gaagcgattg gaccatcact tcaaaagacg
    26881 gtctgaaatt atcagcgatt tatcttcctg ctgaaacgaa aagtgaaaaa acagctcttg
    26941 tggctcatgg ctatatggga aacgctgaaa cgatgaccaa ttacgcaaag atgtttcatg
    27001 atatgggtta caatgtcctt gttcctgatg caagaggaca tggaaaaagc gaaggggatt
    27061 acattggatt tggatggcca gagcgtaaag actatgtaca gtggataaac aaagtgctag
    27121 aaaacaatgg aaaatcgcaa gaaatcgttc tatacggtgt cagcatggga gcagcaacag
    27181 ttatgatgac tagcggagaa aaactaccag ataatgtgaa agcaatcatt gaagattgcg
    27241 gttattcttc cgttcatgat gagcttgctt atcagctaga cgatatgttt agtcttccag
    27301 catttccgct tatgcaagta acgagtctag tgacaaaagt ccgtgctggc tactttttcg
    27361 gtgaagcaaa tgcagtggaa caattgaaga aaaaccagcg cccaatgctc tttatacatg
    27421 gagacgaaga tacatttgta ccatttgaaa tgttagataa ggtctatcgt gcaacgaagg
    27481 gaccaaaaga aaagtatgtt gtaaaaggag ccgagcatgc ggaagcatac aagacagatc
    27541 ctgaaaaata tcagcaagta gtccaacaat ttttaagcca atatgttcat tgaacgagtt
    27601 taaaagtagg ggatgaaaag aaagaagcct ttgactggat ccagtcaaag gcttctttta
    27661 tcg
//
LOCUS       DAIGWC010000035        27239 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.035, whole genome shotgun sequence.
ACCESSION   DAIGWC010000035 DAIGWC010000000
VERSION     DAIGWC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.035"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(56..1444)
                     /gene="ltrA"
                     /locus_tag="NOB74_001522"
     CDS             complement(56..1444)
                     /gene="ltrA"
                     /locus_tag="NOB74_001522"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI1220715.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(2013..2390)
                     /locus_tag="NOB74_001523"
     CDS             complement(2013..2390)
                     /locus_tag="NOB74_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220716.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            2646..3374
                     /locus_tag="NOB74_001524"
     CDS             2646..3374
                     /locus_tag="NOB74_001524"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HCI1220717.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            3374..3628
                     /gene="purS"
                     /locus_tag="NOB74_001525"
     CDS             3374..3628
                     /gene="purS"
                     /locus_tag="NOB74_001525"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HCI1220718.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            3630..4301
                     /gene="purQ"
                     /locus_tag="NOB74_001526"
     CDS             3630..4301
                     /gene="purQ"
                     /locus_tag="NOB74_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HCI1220719.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            4302..6524
                     /gene="purL"
                     /locus_tag="NOB74_001527"
     CDS             4302..6524
                     /gene="purL"
                     /locus_tag="NOB74_001527"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HCI1220720.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            6509..7948
                     /locus_tag="NOB74_001528"
     CDS             6509..7948
                     /locus_tag="NOB74_001528"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HCI1220721.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            7971..9023
                     /locus_tag="NOB74_001529"
     CDS             7971..9023
                     /locus_tag="NOB74_001529"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HCI1220722.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            9020..9598
                     /gene="purN"
                     /locus_tag="NOB74_001530"
     CDS             9020..9598
                     /gene="purN"
                     /locus_tag="NOB74_001530"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HCI1220723.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            9595..11130
                     /gene="purH"
                     /locus_tag="NOB74_001531"
     CDS             9595..11130
                     /gene="purH"
                     /locus_tag="NOB74_001531"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HCI1220724.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            11146..12420
                     /gene="purD"
                     /locus_tag="NOB74_001532"
     CDS             11146..12420
                     /gene="purD"
                     /locus_tag="NOB74_001532"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HCI1220725.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            12542..13456
                     /locus_tag="NOB74_001533"
     CDS             12542..13456
                     /locus_tag="NOB74_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI1220726.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(13589..15154)
                     /locus_tag="NOB74_001534"
     CDS             complement(13589..15154)
                     /locus_tag="NOB74_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI1220727.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(15147..16598)
                     /locus_tag="NOB74_001535"
     CDS             complement(15147..16598)
                     /locus_tag="NOB74_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI1220728.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(16612..17628)
                     /locus_tag="NOB74_001536"
     CDS             complement(16612..17628)
                     /locus_tag="NOB74_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1220729.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            17848..18936
                     /locus_tag="NOB74_001537"
     CDS             17848..18936
                     /locus_tag="NOB74_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HCI1220730.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            18990..20516
                     /locus_tag="NOB74_001538"
     CDS             18990..20516
                     /locus_tag="NOB74_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HCI1220731.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            20518..21723
                     /locus_tag="NOB74_001539"
     CDS             20518..21723
                     /locus_tag="NOB74_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1220732.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            21980..22957
                     /gene="guaC"
                     /locus_tag="NOB74_001540"
     CDS             21980..22957
                     /gene="guaC"
                     /locus_tag="NOB74_001540"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HCI1220733.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            23221..24645
                     /locus_tag="NOB74_001541"
     CDS             23221..24645
                     /locus_tag="NOB74_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCI1220734.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            25106..26215
                     /gene="pdhA"
                     /locus_tag="NOB74_001542"
     CDS             25106..26215
                     /gene="pdhA"
                     /locus_tag="NOB74_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HCI1220735.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            26218..27195
                     /locus_tag="NOB74_001543"
     CDS             26218..27195
                     /locus_tag="NOB74_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HCI1220736.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT         8626 a         4770 c         6042 g         7801 t
ORIGIN      
        1 aactgacctt ccgcccctct cacaccaccg tacgtacgga cccgtatacg gcggttcaat
       61 aagttgagtg tacgaactgg tacttcaagg agatgtcctc atatccttgg cgggccagtt
      121 ctttgtctgt taatgatcga tgaagaatat gacttttgga gactgaccaa ataccttttc
      181 ttgtatttga ccattcatac gctttcgctt tatcgatccc taaacgaatc agattttttc
      241 ttttggttct tggattcttc cattgtttcc aaatatattg tctgattctt cgcttcaacc
      301 aaccgtttaa ctccctcatg aattctttca tctcaccaat tccatagtag ttgatccaac
      361 cagtcattag ttgcttgatt tcttttaaaa taagttggat acttcttcca cggtttcttt
      421 tagtgagttg tttgagcttg cttttcacac gctgttttgc ttttgcgtga gggcgaattt
      481 taataccttt ctttgttggc agaatgcaga atccaagaaa ctttcgtttc aatggacttc
      541 ctaccgcact cttttctcga tttaccgtca actttagttg ttcttcgaga aattgaatgg
      601 atttcttcat cacacgctgt cctgctcgtt tgcttctaac atagatattg cagtcatcgg
      661 cgtatcgaac aaatttatgt cctagatttt ctagcacttg atcaaattcg ttcaggtaga
      721 tgttacttaa caggggagag agattgcctc cttggggcgt tccttcttca gttgttgtga
      781 tgagtccatt ttccattaca ccactcatta agtattgacg gatcagtttt aggacttgtt
      841 tgtcctttac tttccgctca atgaaataca tcagcttatc gtgatttacg gtgtcaaagt
      901 aggctttcat atcaatgtcc accacatatc ggtaaccttg ttcataataa gattttgctt
      961 tcttcactgc gtcatgtgcg ctgcgatttg ggcgaaaccc ataactatta tctgagaatt
     1021 ctggttcaaa tagcggttgt aacacttgat tgattgcctg ttgaagcata cgatcaataa
     1081 ccgtgggaat tcctagtttt cttacaccgc cgtttggttt cggtatttct actcgcaaaa
     1141 caggctgagg tttatagttc ccttggcgta aattggatag taattcctcg cggtgctctt
     1201 tcaagtaagg aagcagttga tcgacggtca tcccatctgc accagccgcc cctttatttc
     1261 tgactacttg aagatacgct tgattgagat tattccgatc tagaattctc ccaaacagat
     1321 tttctacacc atcttgtttc ctctgttcac cgcaagaagt gctgcgcact tcatcatacc
     1381 cttcgtgttc cacactagct ctttgatgat agccaagttt tcttgttttc tgcggtcgtc
     1441 gcatcttctc acacctccta aattattcaa gattcttatt gttcagtcct tcgtaacggt
     1501 cagtgtcgtt actactatga cctcggctga cttctcatga ttcaccatca tgtcgccatg
     1561 atcgttgtgc tggtttgttt tcattcaacg cccacaacac cctcatgaga tctcccccgg
     1621 taagagtgaa aactttcctc ccatgtaact gctagattta ctgtataggt ttcgggcagt
     1681 attggacttt gtcttgtgat gaagacttat ccgacctaat tcagccttgt atctagtttc
     1741 tgttcgtcag ttcaggagtt tgcgtccgac ttccttcagc cacaacctca cgattgccgc
     1801 cttgtctttc gctaacagtt cctactgcca agcctgtagt ggactttcac caccaagttt
     1861 tcacccatgc agggcgcaca ccaaaaaaga agcagatccg ttagcggttc tgcttctttt
     1921 agtttattat attttcttat caataatagg aacctgattt taaaagcggc tacctcttta
     1981 ccgtgcctct ttacatacaa aaaatagagg aattaagcgt aaatggcttg gctattataa
     2041 ctaaaatgct ggttatggag atgttgcagc aagttttcga gaaaagcgta ttccatctct
     2101 tgtccattga ataagatctg gatacgataa tgatttttga aacgcttctg ttcatgaatc
     2161 tgactgattg aaagttcgcc tttgtgttct gtctgataaa gaaaagtcct tttacggcat
     2221 tcagcacagc gcttggttgc tcggcggatt tttcggaatg tataaaaact agtatcttta
     2281 ttgcataaat aaacgtcttt gatcgacagc aaatcattat atagacagga acgttcttca
     2341 gctgttaatt ctgataaaaa aagctgacct tgttttattg catcttccat cggcaagtgc
     2401 ctcctcgaac ccattatcca aatttttagt taattctaat ataccatcat taagtataaa
     2461 tgtaaacgct tgttgatggt ataagatttt cgtttctgat aaaacacgaa cattaaaaga
     2521 atctaatgcc ttaaatgtac atatttttgt tgatttataa aaagatgatt gctaaaattt
     2581 aaagtgaaaa aacgaacaaa aaacgatgta tttgctttta atgtaaataa aaaggagaga
     2641 cgtacatgga gaagaaagaa cttttgtatg aaggaaaagc caaaaaaata tatcttactt
     2701 ctgatgagaa cttgatttgg atagaatatt tagatcaagc aactgcgttg aatggcgcga
     2761 ggaaagacca gataagtgga aaaggagaat tgaataatca aatcacaagt gcaattttcc
     2821 gttatctgac tcaaagagga ataaaaaatc attttattga acaattgtct aaaaccgaac
     2881 aattagcaaa aaaagtacaa attatccctc tggaagtggt tatccgaaat attgcagcag
     2941 gaagtttctc aaaacgtcta ggtgttcccg aaggtaaaga attcatcaaa ccaatcattg
     3001 aattctacta taaggatgac cagttggatg atccatttat caatgaagag catatctatt
     3061 tcttacaact tgcaaagccg gaagaaatca gtgagctgaa agcccaagcg ttggctatta
     3121 atgaaatttt gaccgaatta tttgctaagg tcggtttggt tttagtagat ttcaagctag
     3181 aatttggccg gtcgaatgga caaattttgc ttgcggatga agtaacaccg gatacttgcc
     3241 gattatggga tgaacgtacg aatgaacata tggacaaaga cgtttaccgc agagatctag
     3301 gtgatttgat cccagtctat caagaagtat ataaccgtct atcggaacta actgaagaaa
     3361 aggagcgagt atgatgtatt tcgtaaaagt atatgtaacc tataaagatt cagtgttaga
     3421 tcctcaaggg gaggcagtaa aaaaagcagt ccatcgtatg ggatatgaaa caatcgaaga
     3481 tatccgaata ggaaaatact ttgagataca acttgctgat gcagaagaac caatcgatac
     3541 agtgattgaa acgatttgtg acaagctgct tgcaaatgta aatatggaaa cataccgata
     3601 tgaaatcaaa aaaatggagg aagtataaca tgaaatttgc ggtcatcgtt tttccaggtt
     3661 caaattgtga cgcagatatg ttatgggcag ttcgcgagat catgggcgct gatgccgaat
     3721 ttgtacggca tgatgagtcc tctttagaag gatttgatgg ggttttactg ccgggaggat
     3781 tctcctatgg tgactatttg agatgcggtg cgattgctcg gttttctaca atcatggaag
     3841 aagtgattcg ttttgctgaa gaagggaaac cagtattcgg tacatgcaat ggattccaga
     3901 tattgacaga agcaggactt ttgccaggtg tactgagacg aaatgagtct ttgcatttta
     3961 tttgcaaaac tgtaccattg aaagtcaacc ccaagacggc ctttacttca gagtatgaag
     4021 ccgacgaaat aatctatctt ccagttgctc atggggaagg aaattatttc tgtgacgaag
     4081 aaacacttca agaactaaaa aaaaataatc agattgcctt tacttataat gacaacatca
     4141 acggcagcgt ggaaaacatt gcagggatta cgaacaaagc agggaatgtg ttaggaatga
     4201 tgcctcatcc agaacgtgca gtagaagact tgctaggatc agaagatggg aaacggttct
     4261 ttgcttccat tttaaaaaac ttcggaaagg tgaccgtata gatgaaaaca ttgaaagaac
     4321 cgacagctga agagatcaag aaaaaaagaa tctatgccga atggggattg actgatgaag
     4381 aatatcgaat gatcgaagaa gatatcttag gaagaatgcc taattatacg gaaactggac
     4441 tgttttctgt tatgtggagc gaacattgtt cctataaaaa ttctaaaccg gttctacgca
     4501 aatttcctac tagtggacct catgtgttgc aaggccctgg agaaggcgca ggcatcgtcg
     4561 acatcggtga tggactagca gttgtcttca aagcagaaag tcacaatcat ccttcagccg
     4621 tggagcctta tgaaggagct gcgacaggag ttggcggaat catcagagat attttcagca
     4681 tgggggctcg tccaattgcg ttgctagatt cattgaggtt cggcgaatta gataatccaa
     4741 gaacgaaata tttactagaa gaagtagttg caggtatcgg cggatacggc aattgtatcg
     4801 gcataccgac tgtaggcggc gaaattgcat ttgatccttg ttatgaagga aacccattag
     4861 tcaatgcaat gtgcgtaggt ttgattgaac acaaacatat ccagaaaggg caagccgctg
     4921 gcgtcggtaa ttcgatcatg tatgtaggtg caaaaacagg tcgcgacggt atccacggag
     4981 caacttttgc ctcagaagaa tttaatcaag aagaagaaca gcaacgttct gctgtacaag
     5041 taggcgatcc ttttatggaa aagctgctgc ttgaagcgtg tttggaatta atcttgcatc
     5101 attcggattc tctaataggt atacaggata tgggagcagc aggacttgtt tcatctagtg
     5161 cggaaatggc ttcaaaagct ggctcaggac ttatattgac attagatgaa gtcccacaaa
     5221 gagaaactgg gatgacacct tatgaaatga tgttatcgga atcacaagaa cggatgttga
     5281 tttgtgttaa atcaggagag gaagaaaaaa tccaagaact atttcagaag tatgatctag
     5341 atgcagtcac tatcggtaaa gtaacagacg acgggcaata tcggctatat catcaaggag
     5401 aagaagtagc aaatctgcca gtcgatgcat tagctgaaga tgcaccagtt tatcataaag
     5461 aaatgaaaga accagctcga atcgtagaat ttcagcagtt agctccttat cagccagtta
     5521 tcgaagaacc tggacaagta ttgcttgatc tgctgcagca accgacgatt gcttcaaaac
     5581 gttcaatcta cgaaacttat gattcacaag tacaaaccaa tacagttgtc cgtccaggaa
     5641 gcgatgctgc tgtgatgagg gttagaggga cgaataaagc gttagctatg accacagact
     5701 gcaacgcgcg ctatctgtat ttggatccaa aaatcggagg acaaatagca gtggcagaag
     5761 ctgctagaaa tattattgct agcggtggta agcccttggc gatcaccgac tgcctgaact
     5821 atggttctcc tgataaacca gaagtttttt gggaattatc gacttcagct gacggaattg
     5881 ctgctgcgtg tgaaacgtta ggaactcctg ttatttcagg aaatgtctct ttatataatg
     5941 aaacggatgg tcaagcaatc tatccaacac caatgattgg tatggtcgga ttgattgagg
     6001 atcataaaca tatcactact caggaattca aaaaatcagg ggatctaatc tatatattag
     6061 gtaagacgtt tgcagatttt gatggcagtg aattacaaaa gatgcagctt ggaagaatcg
     6121 aaggtgtgat ccgaaacttt gatctatcca ttgaaaagag aaaccaagag ttagtattga
     6181 cagccatcca aaacggattg attgaaagtg ctcatgactg ttcagaaggt ggcttggcaa
     6241 ttgcactggc agaatcagct ttcaaacatc agctagggat atctgtacag tttgaattgt
     6301 cctctgctca attatttgca gaaactcaat caagatttgt gttgacagtc gcaccggaaa
     6361 ataagacacg attcgaagaa atgatgggag atgctgctgt tttagcaggt aaggtgacgg
     6421 atgaagcgat aatcgaaatt tcagcaactg acggtcagat caaaatagaa actgcagtag
     6481 caagaaagtg ctgggaggat gcaatcgtat gtcttatgaa gtgaagagtt taaatgaaga
     6541 atgcgggatc ttcggtgttt ggggtcatcc agacgccgct agtgtggcat acttcgggct
     6601 ccatagtctt cagcatcgag gacaagaagg tgcaggtatc gtgtccaatg atcgaggaaa
     6661 gcttaagggg catcgagatt tggggctgct ttctgaggta ttcaaagatc aaagaaaatt
     6721 gcagcagtta acaggagaag ctgcaatcgg acatgtacgt tatgcaacag caggcaatgg
     6781 aagtgtggac aatattcagc cttttctatt caaatttcat gatcagtcga tcggcttagc
     6841 gcataatggt aacttgatca atgctcgttc ccttagaaaa gagttagagg aaaatggggc
     6901 gatcttccat tctaactccg atacggagat attgatgcat ttgatccgac gaagtgaaga
     6961 aacagatttt ttaaataaat taaaaagtgc tttgaatgaa gtcaaaggtg gctttgccta
     7021 tttattaatg acagaaacgg caatgattgc cgctttggac ccaaatggtt ttcgtccatt
     7081 agcaatcgga caaatgaaaa acggagcata cgtgattgcc tcggaaactt gtgcattaga
     7141 agttattggg gcacgtttta taagagatgt ccagcctggt gagatagtga tcatcaatga
     7201 cgaaggaatc cagattgatt gctttacgaa ggacacgcag ctttctattt gttcgatgga
     7261 atatatctat tttgccagac cagattcaaa catcgcaggg atcaatgtgc atactgcacg
     7321 gaaaaatatg ggacggaatt tagcgaaaga atcgccagta aaagcagata tggtcgttgg
     7381 cgtacctaat tcttctttgt cagccgcaag cggttatgcg gaagctagtg gaatccctta
     7441 tgaaatcgga ttagtaaaaa atcaatacat tgcccgaaca tttatccagc caacgcctga
     7501 gctaagagag caaggtgttc gaatgaaatt atctgctgta cgaggagtag tggaaggtaa
     7561 aaaggtgatt atggtcgatg attcaattgt tcggggtacg acaagcagac ggatcgtcca
     7621 tcttttgaaa gaagcagggg caaaagaagt ccatgtgagg attgcttctc ctcctttgaa
     7681 atatccatgt ttttacggga ttgatattca aacgcgtaaa gaactcattg cggcaaatca
     7741 cacgattgat gaaatcaaag aatgtatcgg tgcagattct ttaggttttt taagtgaaga
     7801 gggtctgatc gaatcgatcg gtctggaaaa agatgctccg tattcaggat tgtgtatggc
     7861 ttatttcaac ggagattatc cgacgccgtt atatgactat gaagaaaaat atcaggaatc
     7921 actaaaagaa aaagtatcgt tcttttaaaa gcagaccaag aagggagtat atgaattcaa
     7981 tggcaaatgc atacgcaaaa gctggcgtag atgtcgaagc tggatatgaa gtagtagaac
     8041 ggatcaagaa gcatgtcaaa aaaacggaac gtttaggtat gatgggcgct ataggaggat
     8101 tcggcggttg ttttgattta tcggtctttc aattaaaaga gccagtcctt gtctcgggga
     8161 ccgatggcgt ggggacgaaa ttagcagtag caatcgaagc agacaaacac gatacaatcg
     8221 ggatcgactg cgtagcgatg tgtgtcaatg atatcttagc acaaggcgca gagccgttat
     8281 atttcttaga ctacttagca acggggaaaa atgatccgtt acgtttggaa aatgtagtaa
     8341 aaggtgtagc agatggatgt gttcaaggaa atatggcgct gattggcgga gaaacagctg
     8401 aaatgcctgg tatgtactca ggtaatgatt atgatctagc cggatttgct gtagggatag
     8461 ctgaaaaatc tcaattattg acaggagaaa cgatcaaccc aggagatgtg ttgcttggaa
     8521 tagcatctag cgggattcat tcaaatgggt actctcttgt tcgcaaaatt ttctttgagc
     8581 agcagcagtt ttctttatca tcaaaactgc cagaattgaa aaaaacactt ggcgaagaat
     8641 tgcttgagcc aacgaaaatc tatgtttctt ccttgcttcc gctgatcaaa gaaaagaaaa
     8701 taaaaggagc tgcacatatc actggtggag ggtttgtaga aaatatcccg cgaatgttac
     8761 cagaatctat ggctgcacaa atcaaacttg gctcatggcc gattcttcca atattcggct
     8821 gtttacaaaa atatggtgaa attcctgaga tggagatgta tgaaatcttc aatatgggca
     8881 tcggtatggt cctggcagtc caagaatcga aagtaaaaga aatagtacac gaaattgagc
     8941 aagctggcga aaaagtttat gaaatcggga aagtgatcgc caaagaaaaa catcgtgtgg
     9001 tgtttatagg agaagaacga tgagaatcgc tgtttttgct tctggaaacg gaagcaactt
     9061 tcaagcgcta gccgattatc tatcgaaaaa aggattggaa tcttcgattg actggttgtt
     9121 ttgtgatcag cctgaagcat atgttttgaa acgtgcaact gcgttgagtg taccggcaga
     9181 ttgtttttca cctaaagaat ttgattcaaa aaaagagtat gaagaagcaa ttttgcataa
     9241 attgaaagaa aaaaagatcg atttgatcgt attagctgga tatatgcgaa tcattggacc
     9301 ggtattgctg aaaaattatg ataaaagaat catcaatatc catccgtctc ttttacctgc
     9361 cttccctggt ttgcatggca tacgtgatgc ctttgaagct ggagtaaaag aaacgggtgt
     9421 cacaattcat tatatcgacc aaggtgtaga tactggacca atcatccggc aggaaaaagt
     9481 gagaattgaa caggaggaca cgttcgattc tttagaagaa aaaatccata gagtagagca
     9541 tcgaatctat ccagaagtga ttagtgaaat tattgaaaat ggaggctatc tgaaatgaca
     9601 agagcattga tcagtgtatc agataaaact gggattgtag cattcgccca aggtttgatt
     9661 gaacaaggag tagaaatcat ttcaacagga ggaacaaagc atgcgttgga taaagctggg
     9721 atcaaaacgc tttcgatcga agaagtgaca gggtttcctg aaatgatgga tggccgtgtc
     9781 aaaacacttc atcctaaaat ccatggtggt cttttaggaa gacgcgatct ccctagccat
     9841 atggaggcaa tggaaacgga aaatatccaa ccaatcgact ttgtttgtgt caatttatat
     9901 cctttcaaag aaacgattat gaaaccagat gtcgaaatag cagaagctat tgaaaacatt
     9961 gatatcggtg gtcctagtat gctccgtagt gcagcaaaaa accatgaatt tgtcacctct
    10021 gttgttgatc catctgacta tgaagaagta ctttcagaat tacgtcagta tgggcatact
    10081 tcactttctt tcagacaaaa actagcggca aaagtctttc gtcatactgc ggcatatgat
    10141 gcactgatcg ctcaatactt aacggattgg gtggaagaaa aagaaccgga aaaattgaca
    10201 cttacgtatg aacgaaaaca aacgcttcgt tacggtgaaa atagccatca agccgctgcc
    10261 ttttatcagt ccgctcttct ggaaaaatat tcgatcgcag cagcaaaaca actccatggg
    10321 aaagaacttt cttataataa tatccgagat gcagatgctg cgctacggat catgaaggaa
    10381 tatgacgagc caacggtagt cgccttgaaa cacatgaatc cttgtggtat tgggacagca
    10441 tctacgattt tagaagcgtg ggaagcagcg tatgaagcag atcctgtttc aatctttggt
    10501 gggatcatcg ttttgaatcg agaagtagat ctgccaacag cagaacagat gcataagctg
    10561 tttctagaaa tcatcattgc cccttcttat acacaagaag ctttggaatt actgcaaaaa
    10621 aagaaaaaca tccgattact gacagtagac tttgcgcagg aagaaaatca aaatcgagaa
    10681 gaaacggtct cagtcttagg tggacttctt gtacaagatc aagatctggc aatagaaaat
    10741 gaagaagagt ggaaagtcgt gacaaaacgt aagccgactc cagcagaagc aaaagcatta
    10801 gcgtttgctt ggagagctgt caaacatgtg aaatctaatg cgatcgtact ggcaaacgaa
    10861 cgtcagacag taggaatcgg agccgggcag atgaatcgag tcggttcagt aaaaattgcg
    10921 attgaacaag cgcaagagaa aatggaaggt gcagttttag ctagcgatgc ttattttcca
    10981 atggatgatt cggttgaata tgcagccaaa catggtataa aagcaatcat tcagccagga
    11041 ggaagcatca aagaccaaga ttctattgat atggcgaata aatacgatct agcaatggtc
    11101 tttactgatg ttcggcattt tagacattag agaggagtcg gataaatgaa cattttggtg
    11161 atcggtgcag gtggtcgtga acatgcaata agtaaaaaac ttttagccag tccgaaggtg
    11221 gatacggtgt attgtgcgcc aggaaatccg gggatgacaa aagatggtat caattgtgtc
    11281 gctatcagtg agcgagatca ttcagcgtta atccattttg ttaagaaaga ggctattgat
    11341 tggagtatcg ttggtcctga agttcctttg ttaaatggga tcgtcgatga ttttatggcg
    11401 gaaggattga aaatcttcgg tccgacaaaa gcagcagctc tgatcgaagg ttcgaaaagt
    11461 tttgctaaac aattaatgga tacttatcaa atcccgacag ctaaatccag aagttttgaa
    11521 tgttacgaaa aagcagcagc gtatatcaaa gaaaatggtg cgccaatcgt agtgaaagcg
    11581 gacggcttag cagctgggaa aggtgtagtc gtggctacca cagtgaagga agcgctggat
    11641 gcggcagaac aaatgttgaa ccagcatcga tttggggata gtagcaaaaa aatcgtcgta
    11701 gaagagtttt tggcaggaga agaattctcc cttttggcgt ttgtccgtaa taccaaggtg
    11761 tatccgatgg tcatttcgca agatcataag cgggcatttg ataacgataa agggccaaat
    11821 acaggcggaa tgggtgctta ttcaccagta ccgcaaattt caaaaaagat gattgaaaaa
    11881 gctgtggaag aagttttaaa accagcggct ttgggaatga aagaactagg acgctctttc
    11941 acgggtgttt tatatgcggg tttgattgct acgaaggaag gaccaaaagt gatcgaattc
    12001 aatgcgcgtt tcggtgatcc tgaaacgcaa gtcgttcttt ctcggttgaa gagtgacttt
    12061 gcgcaagtaa tcgatgattt attagagaat cgtacagtag agttaaagtg gcagcaagaa
    12121 ggatacaatg taggcgttgt ggttgcagct gccggttacc ccgaagaata tgagacagga
    12181 atggttctac cagattttct ggaagaagag ctttctgttt actatgctgg agtttcctca
    12241 aataacggca aactagttgg agcaggagga cgtctttatt tagtagaagc atacggtgag
    12301 acgatcaaag aagcacagaa aaaaatttac accgcgttaa tggataaaac gacagatgga
    12361 acattttatc gtacagatat tggagaaaaa gctgccaata gcgaactgat cgtgaagtaa
    12421 atcagctgct tccatttata aaaaatacaa caaacataat cggaagcgcc gattttagtg
    12481 aagccttttc ataaagagtg tggtacactt ttgttgtgta tataaataag gaggagttca
    12541 gatgaaaaaa attcaattag gtacttctga tcagaaagca gctgcagtga tcttaggctg
    12601 tatgcgtatc aacaatgcgg aagatccagt aaaagtgatt gagacagctt atgaaaacgg
    12661 cattgatttt tttgaccatg cagatattta tggaaacggt gaatgtgaag aaatctttgc
    12721 agatgctcta gcaaaaacat caatcaaacg agaagatctt tttattcaaa caaaatgtgg
    12781 aatcgttcca ggtgtgatgt ttgatttttc taaaaaacat atcattgaat ctgtagaaaa
    12841 aagtttgacc cgtctgaaaa tggattatgt ggatgcttta cttcttcatc gtccagatac
    12901 attggtagaa ccagaggaag tagctgaagc gtttgatgaa ttggaacggt caggaaaagt
    12961 tcgttatttt ggcgtcagca atcaaaaacc aatgcaaatc gaattgctga aaaaatatgt
    13021 tcgtcaacca ttagtagcta atcagctgca atttggcttg aaacatactg gaatgatcga
    13081 tcaagggatt catgtcaata tgacagatga agcaagtatc gatcatgacg gtagtgtact
    13141 tgattattcc cgattgcatg atatgacgat ccaagcatgg tcaccatacc agtatggatt
    13201 ttttgaaggt gtatttatcg ggaacgaaaa attccctgaa ttaaaccaaa cattagaaga
    13261 actagcagct aaatatcaaa cgacaccaac tggcttggct tctgcttgga ttttacgcca
    13321 tccagccaat atgcaagtga tcgccggtac gatgaacgta gggcgaatca aggaaatcgc
    13381 tcaagcttca gaaattaata tgtctcggga agattggtac gaattgtacc gtgctgctgg
    13441 aaacatttta ccttaaagat tgtcataagc aggtcaaaag ggctataaat taaaaagaca
    13501 gaataacttg aaagctgttt tcagcttcga gatattctgt ctttttttat tgcaaatgga
    13561 aagagtatca ttgtacggat ttcgtttatt agttattttt gtttttaagg aaaagctgtg
    13621 tccgatattc ttttggagaa atcccttgtt ttttcttaaa taaataactg aaatagttag
    13681 ggtcattata accaatttca aaagcaatat ctgaaatacg atagtctgat tgctgcaata
    13741 atttttttgc taattcgatt ctttgttctg tcagataatc gatgaatgtt tggttaaacg
    13801 attgagaaaa aatcgtactg aaatgagagg gacttaatgc aacttgttga gcgacccaag
    13861 ttaaggacat atctggatcg gtaaaatttt ctttgataaa atccaatgca tggttcaaaa
    13921 ttggctgata tttgttcctt gaaggctgtg agggcagagc agttaagaaa gaaatgaaca
    13981 tataaactgt cgaacggtaa agcgagtcgt cggcgctgat tgctaagcgt tgactggtgg
    14041 atgtgcaatg aaccatttct tgcgggattt tcttttcttt caggcagaca tgctggagta
    14101 gcttagtcaa gacaaataaa cgatataatc gtgttcgagt tggtgtgcct tgtggtttcg
    14161 tcaagtgttc gatgtactta gatacttcgt ttttcgataa tgaagacaaa tcaagtgaga
    14221 ggtcaaagta aaagacagaa tcaactggaa gtttcgcttc ttgaatcaaa tcctcatagc
    14281 tgataatttg ttctttaagg gaactggcgg tttcaagtat catctgcgtg atctcaaaag
    14341 atgcaggtaa ttcgctgatt ctttctgcga caggaccaat ggcgacagaa aaattatttt
    14401 tttgtccctt ttctaattca tggaccaacg tttgggctac ctgataactg gtctcgatca
    14461 cattttcttc aagagaatca actattaaaa atttgatgaa tcgagaggaa acagcagaga
    14521 agatcacttg ttgattctcc ctaaataaaa acttcaaata atcactgaga tgagcgtaat
    14581 cttcaaagtc tgtactgact tggtttgctg ctaataatac ggtcattttt ttccctgcta
    14641 aagagcgatt gaaagattca gcaagtttca atgtttcact gatcgtaagt gagcctttga
    14701 acaaaccgtt caagaaatga ttttttttca attcgaaaac aagatcagaa gaagtgtgcg
    14761 tttctttttg ctgcaaatct aaagcagtta ctgctttttc tattgcttgt ttcaattcgc
    14821 tacttttaat cggtttaagc agataatcat ctgcctgtac ctggattgct cctttcatat
    14881 aatcgaaatc gtcgaatcca ctaataaata tgagacgagt ccaaggaagt agtttccttg
    14941 cttcttttga aaaagtcaac ccgtccatga aaggcatttg gatatcagtc agaatgatgt
    15001 cgggctgtaa gtcgataatt gaagacagtg ccatctcacc atctccagct tcgccgacat
    15061 aagtgattgg ataataagaa ccaaggacag ttatttgttc ccgcaagtta ttgcgaatga
    15121 ggtattcgtc ttcgatgata aaaactttat acatgtttgt ttcctccaat tgttttggga
    15181 gatagaggga tcatcagtgt gacagttgtt ccttctcggt atttgctgtc aatcgtgata
    15241 ggtttttgat catttccgta ataaagaagg agacgcttgt ttacgttgta aagtccgtag
    15301 ccgatactga aatctgaatc gatccctttg gctaactctt tacgtatttc tgccagtttt
    15361 tctgcaggga tgccaatccc gttgtctata actttgaatt ggatcatctc atcaattttg
    15421 catgtggtaa tacgaataaa tcctttgtga cggacgtact tcgttccatg gtatacagca
    15481 ttttcaatca atggctgcaa gatcattttt aaaatagaaa caggaaaaag tgtttctggt
    15541 atatcgatct tatagtcaag catatggccg tatcttattt ttaagatgac tagataatca
    15601 ttgatatggc taatttcttt ttcaagagga atccagtctt gtcctttgct taaagacgta
    15661 cgaaaaaagc cggaaagtgc atgggtcata gtcagagctt cttcaaagca gtcttgttcg
    15721 atcaaagaaa taatggcatc caaactgtta taaataaaat ggggagtaat ctgagcttgc
    15781 aatacacgaa cttcactttg tgctaaatgg tattgtttca aagcgttctc ccgtaaagac
    15841 tggtttagat cttccgccat tttattcatg ctagcggtaa gtgtttgtaa ttccagtgtt
    15901 tccggcaggg ttaaacgaaa gccaaggttc cctgaagaaa gttgttctga catctcgatc
    15961 agctgattga tcggttcttg gacctttctc tctaaaaagc gacgattctt tttcgcatag
    16021 aaaaaaatgg tactaagaac tccaagttcc actattgtta atagaatgag cgagcggaca
    16081 agtgtcgtat tttttttgct tgctaagtcg atctccacac gaacaaaatc ttgtaagata
    16141 tctgacagca gttgagtgac agaatctacc tgattgatga tctcttcatt ggtatccata
    16201 aaatcttttg ccaagatatt attgatcagc tcgttttgat aatcttccag tgtatcgatc
    16261 gtacgtagcg atacatctaa cgtactaatt tctttaagtg tatttgtatt atttttgatc
    16321 tctcgaatat cattcctaag ttcttctagg atattttcct cattgaactc atctacggtt
    16381 acttggccag aaatcaagtc ccacatactt tccaaaactt tttgatcaac cttcaaagca
    16441 attgcatctg ctttttggat atttgcgatc gtctgttgat aaatcaaaag ctgttgcgaa
    16501 tataacagta tgctcagtag caaagggata acagcaaata gaagcatggc tttgtttgct
    16561 tgggcaaaaa tctgttttat gcttaaattt tttgtcatga tacttctcca gtcaataatt
    16621 tctggttggg atgttagcta tattctgctg ggaaaagaca gtctcggaaa taaaaatatc
    16681 tttaggtaat gtttttcctg tttgaatatt tccaaaataa cgagtaacgg tattggctac
    16741 ataccagccg acatcaggtt tacactcgac tacacaattg acgattcctg agcgtagctt
    16801 ctcgatcata tcttcttgtc catcaatagt tacaatgatc aaatcttctc caggtttgat
    16861 tgatgtttct tttatcgcag ctaaagcacc gtgagtcatt tcatcactat ggctgtataa
    16921 tacatcgatt tcggataaat catttgtttc taaatatcgt ttcatctggt cttttccttt
    16981 catccgaata aaatcaccga caattcggtg aacaatagtc atcggaggtt tatggtcgat
    17041 ggttccatct ttttttaggg ttggtttacg attgattgat tccaaaaatc cttcggagcg
    17101 tagcttggtc ggtgtggagt tctctgaacc agcaagttct aggattctga tttcctgttt
    17161 ctttgaattt gtgaagtgat tgctgacaaa taaacccgcc cgatttcctt ctgctttgaa
    17221 actggggcca atgtgggtga cgaaaagctc gggatcattc gtttgaatat gtctgtcgac
    17281 aagtatgaca gggatccctg ctcgctttgc ttcttttaat acagagtccc acccggattc
    17341 ttgcaaagga gtaaaaatga tcatatccac tttataggca atgaacgtcc gtatatcttg
    17401 gatttgccgt tcctgattca tgtagccatt tcggtagaga acttggtaat cttctttttc
    17461 aagcgcagtg ataattgatt cagtatgctt tttccgccag ctactctccg ttcctgattg
    17521 cgaaaaacca acgactagtg ggtcaggtgc ttcctttgta ttaggtgtac accccatcat
    17581 ttggtaagcg attacaacaa gggctaaaaa aaataaaaca cgtttcactt taaatcactc
    17641 catctggatt tgttagtact atcttatcag ataaaaggga aaatcaaagt caaaaggaat
    17701 caatcgaaaa aaatccaaga aacttaaaaa aatccaagac aaaaaaagta cacctaaaaa
    17761 atttaaagta aatcccataa aaaaatcaat gttaacgctt tctttattag ctatactcgg
    17821 tgtatcaatt gaaatggggg ataaaaaatg aaaaacaaat ttagaaagat tgttgggact
    17881 atcgctattt tgaccgcaag cattctatta agtgcgtgtg gcaattcagg atctgcagat
    17941 gatagtacgg ggtatgtagg aatcgctatg ccgaccaaat cagcagaaag atggatcgct
    18001 gatgggaaca acatggtctc ggaattagaa aaactgggtt ataaaacaga tcttcaatat
    18061 ggagaagata aagtagaaaa tcaagtagca caaatagaaa atatgattac aaaaggggta
    18121 gatacacttg tgattgcttc tatcgatggt tcggctttaa ctgatgtgtt agctaaagca
    18181 aaagaagcag atatcaaggt gatcgcctat gatcgtttac tgatgaattc agaaaatgtc
    18241 gattattacg cgacttttga taattttgga gtaggtgtat cgcaagcagc ttatattgaa
    18301 gagcacttag gattgaaaga aggaaaagga ccattcacga ttgaattatt tggtggctcg
    18361 cctgacgaca acaacgcact aatcaattac aacggagtga tgtctgtttt acaaccatat
    18421 atggacaacg gtcagttggt cgtgccatct ggacagacga gtttcagtca aatcgctacg
    18481 cttcgctggg atggttctac ggcgcaagca aggatggata atctgttaag cgcaaattat
    18541 actgaccaaa cattggatgc tgttttgtcg ccatatgatc caataagttt aggaatcatt
    18601 tcgtcattaa aaggcgtggg gtatgggagt gaaagtaaac ctttacctgt gattactgga
    18661 caagatgcga cagttgctgg cgttaaatcg atcattgccg gggaacaaac acaaacgatc
    18721 tttaaagaca cacgtatctt agcaaaaaat acgattgaaa tgatcaaagc aatcagtgat
    18781 ggagaagagg ttccggtcaa tgatactgaa acttatgata atggggtgaa aactgtccct
    18841 acgtatttag caaatacagt atctgtcgat aaagataatt atcaagcaga gctgatcgac
    18901 accgattatt ataaagaatc cgatctgaaa aattaagagg aaccaaacaa ggaactaaag
    18961 agatctaagt cagagagagg ataagaatta tggcggattg tattttaaaa atggcagata
    19021 tcaccaaaaa attttctgga atccgagcgt tagattgcgt gaatctgatg attgaacgtg
    19081 gggaaatcca tgcattgtgc ggagaaaacg gagcgggaaa atcaacattg atgaatgtct
    19141 tgagcggctt gtatccatat ggctcctatg acggggaaat cttttatgat ggaaagctgt
    19201 gtcaatttaa agatttgaaa gatagtgaag aaaaaggcat cgtcatcatt catcaagaat
    19261 tagcactaag tccttatctt tcaataaaag agaatatttt tctcggaaat gaacaagcag
    19321 aaagaggcgt gattgattgg gaactgacag aaaagaaaac atatgaactg ctgaataaag
    19381 tcggtttgtc tatcgacccg aatcttctag tatcccagat tggcgtaggg caacagcaac
    19441 tagttgaaat agctaaagca ttatcaaaat ccgtccgtct gttgattttg gatgagccta
    19501 ccgctgcatt gaatgaagaa gaaagcgcga atttgctgag attgatccga gagttgaaag
    19561 agcaaggtgt aacctccatc attatttcac ataagctgaa tgaaatcgtg gatatcgcag
    19621 atcgaatcac cattttacgg gatggacaga cgattgagac actagaaaat gaaatgatca
    19681 gcgaagagca tattattcgc ggaatggtgg gcagagattt agttgatcgt tatcctgaaa
    19741 gaaaaccgga tattggagaa gtttatttta aagtagaaga ctggacggtc tatcaccctc
    19801 ttgatcacga gcgaatcata aacgaccaca tcaacttgca tttgaaaaaa ggagagattg
    19861 taggaatagc tggactgatg ggagcgggca gaactgaatt cgctatgagt ctatttggac
    19921 attcttatgg aagcaagata tccggacgta tattaaagga aggggcagag atatcagtta
    19981 agaccgttcc ttcagccatt gcaaacggac tcgcttatgt ctcggaggac cgaaaatctt
    20041 taggactgaa tctgctgatg gatattcggg aaaacgtgac gctgagcagt ttggataaaa
    20101 taagtcaaaa aggagtatta gataaagaaa aagaagtaac tgaggcagaa aatttccgga
    20161 aaaagatgcg tataaaaaca aactccatcc atcaaattgt cagtagtctt agtggtggga
    20221 atcaacaaaa agtcgtttta tccaagtggc tgatgacaca acccgatatt ctttttttgg
    20281 atgagccaac ccgtgggata gatgttgggg caaaatatga gatctacacg attatcgaag
    20341 aaatggcagc aaatggcaaa gctgtctgtc ttatctcttc tgaacttcct gaaatattag
    20401 ggatgtgtga tcgaatctat acgatgaacg aaggacgtat tacaggagaa gtctcgcgag
    20461 aagatgcaga tcaggaagtc ttgatgaaat taatgacgaa agaagaggtg ggttaagttg
    20521 gaacaggcaa aaaatcttac ggataaaaaa gagaaaaaac taaatttgaa aagtagagca
    20581 gctgatcttt ttggtcgcta cagcatggtg atcattttag cgggactact tattgcgttt
    20641 caattgatga cggatggtat tttctggcgt ccattgaata taactaacct tgttctgcaa
    20701 aatagccata tattagtact agctgcaggg atgttattag ttgtgctctt aggtcatgtg
    20761 gatttgtcgg tagggtcagt gatggcgttt gttggtgcaa ttgcgggcat gatgatggtc
    20821 aatcgccaaa tgaacccgtg gatgacagtt atcgcatgtc ttgcagtagg cgggctgatc
    20881 ggcgcatggc aaggtttttg ggtagcttat gcagggatac cggcgtttat cgtgacttta
    20941 gcaggattgc tgatgtttcg tggactgaca caagttgttc taggaggcca atctctagca
    21001 ccttttccag ctgttttcca aaaaatgtct acgggttatt taccagactt aagcgaagga
    21061 agcagccttc acttcttgac attgatttta ggaatgatca tcacgatcgt gttagttgtt
    21121 ggtcaatggc gaacaagaaa tcgtcggaaa aatcatttat ttgaagtgga atctccaaca
    21181 gctttcttgg taaaggcggt atttacagca gtcgttgtac taggaataac ttatatcttt
    21241 gcctcttatc aagggtatcc gattattttg atcattcttg gtttgatcgt tgcagcatat
    21301 gggtttttga caaataaaac agtagcaggt cgacagattt atgcgacggg cggaaatcga
    21361 aaagcggctg aactatcagg gatcaaaaca aagcgaatca cgttctgggt attcgtcaac
    21421 atgggagtca tggcagcttt agctggatta gttttagctg ctcgattgaa tgcggcaaca
    21481 cctcaagcag gtacatcgat ggaactggat gcaatggcgg cagtatattt tggtggtgct
    21541 tcgacttccg gcggcattgg aacaatcatg ggtgcgattg tcggtggctt ggtcatgggt
    21601 gtattgaaca atggcatgtc gattttaggc gtcggggtag actggcagca ggcaatcaaa
    21661 ggattgatct tgcttttagc cgttgtgcta gacttgtata ataagaaaaa acgaacaacg
    21721 taggagaacg ccggttattc agaaaaaaga ctgtgacaag acatttgtca cagtcttttt
    21781 ttcgctaaaa gcgaacattc attgtttcgt ttgtatagac taaaaataat atatgttttt
    21841 ttaccattcg tataaattct ctttttgctc ttgatttttt tgcttaattg agttaaatta
    21901 catagggcgc taaaaaaagc cttgattaaa ttaataatgt tcgtgttttg ctggatgtga
    21961 acatcaggag gataatgtaa tgaaagtatt tgattacgaa gatattcaat taattcctaa
    22021 taaatgtatc gtaaatagcc gttctgaatg tgatacaacg gtcacattag gtaaacatac
    22081 attcaaaatg ccagtagtgc ctgccaacat gcagacgatt attgatgaaa caatcgcaga
    22141 attcttagcg gaaaatggtt atttctatat catgcatcgg tttgatgaag cagctcgaat
    22201 tccgtttatc aaaaaaatga aaaagcgtgg attgattacc tcgatcagtg ttggcgtcaa
    22261 gaaagaggaa tattccttta tagagaagtt ggcagaagaa tcgctaaatc ctgattatat
    22321 cactatcgac atcgcgcatg gacatgctaa ctcagttatt gatatgattc agcatattaa
    22381 aaaatatttg cctgaaactt ttgtgattgc cggtaatgtt ggtacaccgg aagccgtccg
    22441 tgaattggaa aatgcgggcg cagatgcaac aaaagtcggg attggtccag gaaaagtatg
    22501 tattacaaaa atcaagacag gctttgggac tggaggctgg caactggcag ctcttagatg
    22561 gtgtgcgaaa gcagctcgca agccgatcat cgctgacggt gggatcagaa cacatggcga
    22621 tattgcaaaa tctgtccgtt ttggtgcgac aatggtcatg attggttcat tgtttgccgg
    22681 tcacgaggaa tctcctggcg aaacaaaagt cgaaaatgga atcgtgtata aagaatactt
    22741 tggttctgct tcagaattcc aaaaaggcga aaaacgaaat gttgaaggaa agaaaatctg
    22801 gatccaacac aaaggatctt tgaaagatac actagtggaa atgcaacaag accttcaatc
    22861 atctatttct tatgctggag gaagagatct ggaagccatt cgaaaagttg actatgtcat
    22921 cgtgaaaaat tcgattttta atggagacac aatctaaaaa ataaataaaa tattaggatg
    22981 ttgtgaaaaa gttgtcctgc attaagtaat aagaacagcc aaacaaaaat agttctttat
    23041 atgttttgtt tggctggaat tattatcgca gatacaagct tttgaacatc attattcaga
    23101 ataagggact gtgataagat ttttgtcaca gtcccttatg ttttgcaaaa aaagtttttc
    23161 ttttttctcg taaattcggt aaaatcaaaa gaaaaaatag acaatagaaa agagaagctt
    23221 atgtgggaaa aagtagagaa aaaacaagga ccgatttatc gtcaaattat ggaacagatt
    23281 atgagagaaa tcgaaaacgg aaggatcaat cctggaagtc aacttgaatc agaacgaaaa
    23341 ctagggcaac tttttggtgt gaatcgttcc accgttgtcc atgcattgga agagcttagg
    23401 gagcttgggg tactaacgag caaacgtggc agcggatggt ttgttaatca gactgaatgg
    23461 gggaaattcg ctgttccaag aatcgattgg cggcaaatga tctctcctcg ttatgagcag
    23521 acggactggt atgagcaaaa aataagagaa gcaaagcaga tccaaaaaac atcgtttctt
    23581 gatttatacg ctagcgagat gccagatgag cttttgccga attttgagtt tccttcttat
    23641 tctcttgaag aaatcttagc ggaagaaaaa gaaatggatc ttttaggcta tactccgtta
    23701 cgtaacaaaa tcaaacggta tttggaaagt aaatttgaat tggcattttc ccccaaccag
    23761 cttcttgtga ctggtggcgg tcagcaagca atctttttga ttttacaaac gattctttca
    23821 gctggagagg ggatagctgt agagtcacct tctttttttt accgattacc tcttttcaaa
    23881 gcttcaggaa cgcgtttatt tgggataccg atggatgaag aagggatcga cttagaaaaa
    23941 ctgaaagaat cgatccataa aaataaattg aaagcagtgc ttatcaaccc gaattttcaa
    24001 aaccctacag gaaaagtgat gagtcaaaaa cgacgagaaa agctagtaga attgtgtcga
    24061 cagtatcggc ttccaattat tgaagacgat gtatttacgg atctttcatt tctaaaccaa
    24121 gaagaagtcc ttcctatacg aacgattgat ccggataatg tgttatacgt cggttcgtta
    24181 tctagggttt taggaaaaac aacgaaaatc ggttgggtga taggacctga gacttttatc
    24241 tcgcaactag ctcaagcgca agaaatgatg gagttttcga tgaatatcct tacacaaatc
    24301 acagtggcta atgtatttaa tgaagcaatt gatttgaaaa tgcaagatgt aagaaaaaag
    24361 ttgaaagaaa aaagccgact gataagcgct tggggagatt cacaatcgtt tttcaagctt
    24421 cattcaattt taggtggtta ctatgcctgg attacttggg atgggaaaaa actagacccc
    24481 gaactagcag aaaaagtagt agatatgggt cttggaattg caccaagtct actttttggg
    24541 caagatataa atggaatcag aatcaattac agtaggctgg atgaaaacca aataccgttg
    24601 ttttattcaa agatgaaaat tctagaaaag tggttaacag aataatttca caaagtaaat
    24661 agattaaaga atataacagc ttggatttaa atttcaagct gtttcttttt tttcggaaaa
    24721 agaatacgat ataaagaaac taagaaaaaa ccattatttg tacgtccgtt cacgatgtgt
    24781 aaataaaata aatgtttgca acaaaactgt ataacaccaa cgtttttaaa tagaaacaga
    24841 tggttgtaag tttgattaga aaatagaaaa aatgcagatg aaatataaaa cgctttcctt
    24901 attgtgattt tattcactaa tgctgttaat atgcggattg gcataatttc ctttcatcgt
    24961 gaaaatttgt gcttttagct tgtatttctc ataaatccat gataatttat taatgaagac
    25021 ggttaaatag tgatacagtt ttattcactg tttcaatcgc agaatgaaga gattttctta
    25081 tagatgagag aggaatgtgt gacaaatggc aaacaaaaaa gcaccgatcg acttccaagc
    25141 actgctagat gaagtcaatg cagatttccc agtatatcaa gcacttgatc aagatggaaa
    25201 cgtagttaac aaagatttag tacctgattt atccgatgat gaactcgttg aattaatgac
    25261 tcatatggta tggtctcgtg tattagacca acgttcaaca gcgctgaacc gccaaggacg
    25321 cctaggcttt tttgcaccaa ctgctggaca agaggcaagt cagctggcta gtgcttacgc
    25381 atttgataaa gaagatgttc ttcttccagg ttatcgggat gtacctcaac tagtaaaaca
    25441 tggtttacct ttatctcaag cttttttatg gtctcgagga catgctgcag gtaattctta
    25501 tccggaagaa ttgaaagctc taccaccaca aattatcatc ggtgcacaat atgtacaagc
    25561 agccggtgtt gcattaggtt tgaagaaacg aaacaagaaa aatgtcgtct tcacttatac
    25621 tggtgatggc ggttcatcac aaggtgattt ttacgaagca atcaatttcg ctggcgctta
    25681 ccatgcaaat gccgtatttt atatccaaaa caacgggtat gcgatctcta cacctcgtga
    25741 aaaacaaact gcagcaaaaa cacttgcaca aaaagctgtc gcagctggga ttcctggtat
    25801 tcaagtcgat ggaatggatc cgcttgcagt atatactgta tctaaaatgg cacgggaatg
    25861 ggcgatcagt ggaaatggac cagtcctaat cgaaacactg acttatcgtt atggaccaca
    25921 tacactatct ggtgacgatc caacccgcta ccgtacaaaa gacacagatg acgattggca
    25981 gaaaaaagat ccattgatcc gcttccgtaa atatttgacg gaaaaaggac tttggtctga
    26041 agaaaaagaa gaacaagtca tcgaagcaac taaagaagaa atcaaagcag ctattgctga
    26101 agccgacaaa gtaccaaaac aaaaggtttc agatttcttg aaaaacatgt tcgaagtatc
    26161 tccacaatca atcaaagaac aaattgcaat ttatgaagcg aaggagtcga aataatcatg
    26221 gcacaaaaaa caatgatcca agcaatcaca gatgccttag cacttgaact agaaaatgac
    26281 gagaatgtcg ttgtttttgg tgaagatgtt gggaaaaacg gaggagtttt ccgggcaact
    26341 gaaggattgc aggaaaagtt cggagaagac cgagtattcg atactccttt agctgaatct
    26401 ggaatcgcag gattgagttt cggtcttgcg ttagaaggat ttcgtccagt tcctgaaatc
    26461 caattctttg gttttatttt cgaagcaatg gacgaagtag tagctcaaat ggctcgtaca
    26521 agatatcgaa tgagcggcac tagaaatcta cccatcacaa ttcgttcgcc atttggtggc
    26581 ggtgttcata caccagaatt gcattcggat aatttagaag gtttgatcgc tcagtctcct
    26641 ggtattcgag tagtgattcc ttccaaccct tatgatgcaa aaggactatt gatttcttct
    26701 attagaagta acgatccggt tgttttccta gaacacatga aactatatcg ctcattccga
    26761 gaagaagtgc cggatgaagc ttacgaagtt cctttggata aagcagcagt tactcgtgag
    26821 ggaacagatg tatctattat cacatacgga gcaatggtgc gtgaagcaat caaagcagca
    26881 gacaatcttg caaaagaaaa tatatctgtt gaaatcattg atcttcgtac agttgcgcca
    26941 ttagatgtag aaacgatcat tcaatccgtg gaaaaaactg gtcgcgtagt tgttgtccaa
    27001 gaagcacaac gacaagcggg cgttgccgcg caagtagttt ctgagatctc agaacgcgct
    27061 atcctttcat tagaagcccc aatcggacga gtttctgcac ctgatacagt cttcccattt
    27121 ggacaagcag aaaatgtctg gttgccaaat gcaaaagata tcgaagacaa agtaaaagaa
    27181 atcgcggaat tttaagaaaa gaagggacga aacaaagtca tggcttatca atttaaatt
//
LOCUS       DAIGWC010000036        27230 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.036, whole genome shotgun sequence.
ACCESSION   DAIGWC010000036 DAIGWC010000000
VERSION     DAIGWC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.036"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(160..444)
                     /locus_tag="NOB74_001544"
     CDS             complement(160..444)
                     /locus_tag="NOB74_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220737.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(462..1352)
                     /locus_tag="NOB74_001545"
     CDS             complement(462..1352)
                     /locus_tag="NOB74_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HCI1220738.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1372..1590)
                     /locus_tag="NOB74_001546"
     CDS             complement(1372..1590)
                     /locus_tag="NOB74_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HCI1220739.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1560..3260)
                     /locus_tag="NOB74_001547"
     CDS             complement(1560..3260)
                     /locus_tag="NOB74_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HCI1220740.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3527..4300
                     /locus_tag="NOB74_001548"
     CDS             3527..4300
                     /locus_tag="NOB74_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220741.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4381..4950)
                     /gene="thiT"
                     /locus_tag="NOB74_001549"
     CDS             complement(4381..4950)
                     /gene="thiT"
                     /locus_tag="NOB74_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HCI1220742.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5016..5118)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5124..6095)
                     /locus_tag="NOB74_001550"
     CDS             complement(5124..6095)
                     /locus_tag="NOB74_001550"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCI1220743.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6189..7562)
                     /gene="glmU"
                     /locus_tag="NOB74_001551"
     CDS             complement(6189..7562)
                     /gene="glmU"
                     /locus_tag="NOB74_001551"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HCI1220744.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8065..8883)
                     /gene="purR"
                     /locus_tag="NOB74_001552"
     CDS             complement(8065..8883)
                     /gene="purR"
                     /locus_tag="NOB74_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HCI1220745.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9050..9874)
                     /locus_tag="NOB74_001553"
     CDS             complement(9050..9874)
                     /locus_tag="NOB74_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI1220746.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9847..10527)
                     /locus_tag="NOB74_001554"
     CDS             complement(9847..10527)
                     /locus_tag="NOB74_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI1220747.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10550..11488)
                     /locus_tag="NOB74_001555"
     CDS             complement(10550..11488)
                     /locus_tag="NOB74_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HCI1220748.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11733..12596)
                     /locus_tag="NOB74_001556"
     CDS             complement(11733..12596)
                     /locus_tag="NOB74_001556"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HCI1220749.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12738..15311)
                     /gene="mprF"
                     /locus_tag="NOB74_001557"
     CDS             complement(12738..15311)
                     /gene="mprF"
                     /locus_tag="NOB74_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCI1220750.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15452..16258
                     /gene="proC"
                     /locus_tag="NOB74_001558"
     CDS             15452..16258
                     /gene="proC"
                     /locus_tag="NOB74_001558"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HCI1220751.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16337..17893)
                     /gene="rny"
                     /locus_tag="NOB74_001559"
     CDS             complement(16337..17893)
                     /gene="rny"
                     /locus_tag="NOB74_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HCI1220752.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18304..19353)
                     /gene="recA"
                     /locus_tag="NOB74_001560"
     CDS             complement(18304..19353)
                     /gene="recA"
                     /locus_tag="NOB74_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HCI1220753.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19462..20703)
                     /locus_tag="NOB74_001561"
     CDS             complement(19462..20703)
                     /locus_tag="NOB74_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HCI1220754.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20943..21521)
                     /gene="pgsA"
                     /locus_tag="NOB74_001562"
     CDS             complement(20943..21521)
                     /gene="pgsA"
                     /locus_tag="NOB74_001562"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HCI1220755.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21730..22653)
                     /locus_tag="NOB74_001563"
     CDS             complement(21730..22653)
                     /locus_tag="NOB74_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220756.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23391..24677)
                     /locus_tag="NOB74_001564"
     CDS             complement(23391..24677)
                     /locus_tag="NOB74_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCI1220757.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24670..25938)
                     /locus_tag="NOB74_001565"
     CDS             complement(24670..25938)
                     /locus_tag="NOB74_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCI1220758.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26190..26651
                     /gene="mscL"
                     /locus_tag="NOB74_001566"
     CDS             26190..26651
                     /gene="mscL"
                     /locus_tag="NOB74_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HCI1220759.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26710..27156)
                     /locus_tag="NOB74_001567"
     CDS             complement(26710..27156)
                     /locus_tag="NOB74_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1220760.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         7741 a         5872 c         4723 g         8894 t
ORIGIN      
        1 aataccgaga aaatggtttt tgaacatcac ttattcaaaa taaaaaaaga ttgtgacacg
       61 aattttgtca caacctttaa atgtattcct agagcaaaga agctaagcga agaaatccaa
      121 ttctgattat ttattgtatt tctttgttca gcatccttgc taaaagccca tattggacaa
      181 agtattcact acacccatga tctcatcttt tcgagaacgt gctttttctg tcggatcttc
      241 tacctcttct gtgtcaattc gaacaataaa tttccgattc atcgtcacgt aagcaccgtc
      301 gttgatcaaa ataaacagtt cgttctcatt atagtctgca caggcatctt tccatacgtc
      361 aaagccgttt ttttcagaag ggatatcccg tttaaccaca gtttttccac ttaattcgtg
      421 gaacgttacg tcataatatt tcattatctc tacctctttc gtcattcaat attttgtact
      481 tgttctctga ttttttctaa gatcgtctta gactggacga cttgattttt aatttcgatt
      541 gcatttgatt tggaaccgat cgtgttgatt tcccgattca tttcttggat caggaaatct
      601 aattcccgac ctacaggaca ttgtgcttcg ataagttcat ctagtttttg tacatggatc
      661 gccagacgat ccagttcctc gtgaatatct ccgcgttcca acaagatggc tagctccgtc
      721 aacaaccgtt gctcatcgac tttcgctcca agaaattcct ccagcttttt ttgatacctt
      781 atttgaaatt ccttttcata gatttctaca aaactatcga gtttttttag tacttctttg
      841 aattcttcag tattcttttt caacactaaa gctaaagctt gaccttcttt ttctcgactc
      901 gcctcaatag aatcaagtgc gcttttcaat gtatctagag ctaactgtgc caattcttcc
      961 atgctctctt ccggtttttc ttctaccgtt acgaagtttt cgtccagcgc gaagcgttcc
     1021 gccatccgac taattgacac ttgattttga ctaccgtatc gttgttgaat tccgtctgtc
     1081 aattgagtga taagtgaatc aatcaattcc cagttgatga cgatctgttt ttcgtttttg
     1141 ccaatataag ctagattcac aaatacttcg attcgaccgc ggcttaactg ctgtttaata
     1201 agctgacgaa aatcgttttc aacaaagttc aggattttag gacttcgtat ttgaacatct
     1261 agaaaacgct ggttgacact ttttatttca atatctaact gatacgcttt tgtttcgcgg
     1321 atggctttgc caaaaccagt catacttttc attcgacagg gtccttcctc attacatatt
     1381 ttctattgct ttttgcagtt gttcaaactc ttcgttcgtc aatgtcaggc ctttccccat
     1441 tttttcatgg tctggcgccc aatctcgaag atcgaatttt ggcgggcgac cattccagct
     1501 gactaggttc agttctttac gccacccctt gttgttttct gacaatatag cgatttcttc
     1561 tacgatttca tatgaaaatt cttgtgccat ggttgttcct ccttgagata atataaatat
     1621 aggatcagta atgtgtcaac tggttgctta agcaattcat gctgcaaacg atccttgcgt
     1681 tttccttgta gcagataatc aaaataaaca gttttcgtgc gctcattttg tattttttgc
     1741 tggtattttc gataccttcg ccattcttca gtacttaatt gaccaatttg tgccaataaa
     1801 tcatccggca tactttttat atcttgttgg cagatcattt gaatcatcat gtctacttga
     1861 tagatttcat tgggcagtaa aaaatgtttt tttgctaaaa gttctagcat cgccaatccg
     1921 catgtctctg gtacgaccct gttcttatat aaattacgca gtttttgcca aaattttatg
     1981 cttttgaaaa aagataattc taactgaatt tcttttgtta agtaagacaa aaatcctcgc
     2041 cagtatgttc ttgcaggttt aacagaatga aatgtatacc agttcccata gtaatagcct
     2101 aatcgttttt tcatttccag atagcctaat tgtaaattta attggttcct ttggctatca
     2161 aaaagcagaa agctgcctag tgtccacaat gtttgacatt tccaatggat aaaaatgtct
     2221 ggcatacgaa tttttttcgc tgggcctggc ccttgcacat ctacgacaaa tgcctctgtt
     2281 gctcctttgt taatcgcaat atcaataggt attttgttgc gatacccacc gtctgcatat
     2341 ttattttttc cgatctttcg ataagccata gcgggataaa atgaagcaga ggcgagtatc
     2401 caatctggta tttcttctgt ttttgtctgt tggatatcag tcactacttc cgctagttct
     2461 ggcagtttag tagacaccgt atataaacgt attttgggat tatgtttgag taaggacaaa
     2521 tccaaattgt ctttgaccat cttttccaat ggagcagaag aaaccccgcc ttcaattagt
     2581 gctgttttcg tcatttggcg tctttctcga tagaagcgtt cacgaaggtc ttcaactgca
     2641 gccatttctg gtaacgcaag cacttgtctt gtcgacagct ttttccataa attcacagct
     2701 tttttcatat ctccttgtaa aatcaatgcg ccgttcaacg cacctaccga ggtacctgtg
     2761 ataatctcaa agttgatatc atgttccttc agcgcctgcc acacaccaat ctgataagca
     2821 ccgtgcgctc ctcctccacc taaaacaagt gctgtatgat agaccagctt tttatttaat
     2881 tgtgtggttc cttgatagcc gtttttatga aaaatacgca accattcttc tgatagagga
     2941 gattgaaata aaaaacaaca gttttcttta ataaaaaaac gagcgcaagc ttccatatac
     3001 cgaaaaaatt ttttccattc aaaagtttca ccttcaatca acagattatt aaaaataaca
     3061 tctcctctac ttttagcaat agtaaaatag acggtatatt ttttcgatac tgctttaaaa
     3121 gcacattgct tttttgcaga acgccaaaaa gcgtctctac tttcttgatg actttgaaaa
     3181 aatggaaggg gttgttttgc ttgctggata ggcgaataca gcgacatttt ctgtgaaaag
     3241 taaacttttt ttatctccat cgcgctctcc tttttcttca agtataccag tacgtcataa
     3301 aaaggtcatg agtctcgtat tcgactttgt agattccata agaaaacaat tcataaaacc
     3361 tcctttaaat aaaaaaatac aaaaatcaca aaaattaatt gaaaatgaga gtgttttcaa
     3421 tgaaaacgtg attttgtaat ggaattttaa aataaaagaa acaagctttt ttaatgcaaa
     3481 tgttgtaaaa taaaagagat taagaggaaa taagaggagg aacatgatga ctgagtcagt
     3541 ttatgtacat attgatacca caagtaatgc tgttttaaca aaagggctga ctgctactga
     3601 ctttgcaaac agtatcgtgc attttcctca aaacttgctc ttgcttgatc catctgcttc
     3661 tgctggagaa tatgaatccc atacagggct gaaagtaatc cgtggtacag aaaatattca
     3721 gcgtttcttt tcctcttctc gtaacaggcg tggattcgat gaattgaagt ggatcgactt
     3781 tactgattta acgatgctga aagaattgac acctttagaa atttcagaat tattatattt
     3841 tggtcatatg aaaacacatc ttcattcgcc gtttttttat aaactacaga ataattttgt
     3901 atacttcgat cttaatgatc agctgaatcg gatttattat cgctatttag atgaatttta
     3961 taggattttt gctagtaaat taagttcgat cttgtcagat aagatcaatg taaaaaaatc
     4021 ttttttcaaa aaagaaacac ctgttgaaaa aatcagtgtg gaattattga aagaaatgcg
     4081 taatttgatg caggaaggga tcattttttc ttttgatcaa gttggtttga tcgatggtaa
     4141 atatcgtatc ccaatctatg tgattgaaga ttatatttgg aaattaaaag gcacccggta
     4201 tcgagaagag gaaatcatcg ctactttaat ctactctgtc accgatcgac actggcaatt
     4261 ggtagaagat gccgatcttt cttatctgcc attgaagtag atctatttct tatcaaaaaa
     4321 taaaaaggaa acaagaaact aggacatgat tctgtctcaa gtttcttgct tcttttttat
     4381 ttacagctcc tgtcgtttat ctggcacaaa aatcgaagga gtcgtttgtt ggatccctaa
     4441 taaaacgatg atcgttacaa tagctgtact caacccgctg gcaccattca ttacgaaaga
     4501 aaagagccaa ggattcatcc cccatagtgc atacgctccc cagaaaacca ctcctgcaat
     4561 aaaatgccaa aaatatctgg aaagtgcgcc aatcaatgca ccaaacacga tgctttttct
     4621 aatttgtttc gtattatcgt ctacatagcc tttttggaca tttgaagcca tgagccctgc
     4681 tgcgcctgca aaagtatagg caatcgggta ctcaatcaac acttgaacga cacttaaata
     4741 ataaacttgt cccaacggaa aatgtaggat gccccaaatg aaacctgcca gcatccctgc
     4801 ctttgtccct cttcttaacg caaaaagagt caatggaatc tgccctaatg aaatagaaaa
     4861 actgctgccg atctggatcg gaatcaacga caacaccatc gctaacgctg caacaatcgt
     4921 tccttctacc caaactctat tttttcccat aaaaaaactt cctcctttga ataaaaaagt
     4981 cacaaaggag gaagcagctt tcgaaaatag tcaaacagct gtttattcac aattcctacg
     5041 ctcgcataac cgatacaggt acgaagggtt tagaaataga ttcaatctca gcccaattgg
     5101 actccccttt gtgagtttat ttattattta ttttttgttt caaacaatgg actaactggt
     5161 ttgttttcat ggatacgttt gattgcatct cccattagtc cgccaacact tacttcatcg
     5221 attttgtcga ttttacgatc ttctggaaga tagatcgagt ctgtaacaac tagacgctcg
     5281 atagctgaat cttctattct ttgtaaagca gggccggata atactggatg tgtacatgaa
     5341 gcatacacac tagttgcacc agcttctttc aaagcattgg cagccaatgt gatcgtacct
     5401 gctgtatcga tcatatcatc gatcagtaca caagttttgc ctttgacttg tccaatgata
     5461 ttcattactt ctgcaacatt tgcttttgga cggcgtttgt ctatgatcgc aatcggagat
     5521 ttcaaaaatt ccgctaattt acgtgcccgt gtgacaccac catggtctgg tgaaacaacg
     5581 acaacatcat cgcctttgat tcctttttct aagaaataat tggcaataag tggcgcaccc
     5641 atcaaatgat cgactggaat atcaaagaaa ccttggattt gaactgcatg aaggtccaaa
     5701 gtcagcattc ttgttgcacc agctttttga atcatgtttg ctactaattt cgctgtgatt
     5761 ggttcccgtg cacgtgcttt acggtcttga cgcgcatagc cataataagg catgactacg
     5821 ttgattgttt ttgcacttgc tcgtttcagt gcgtcaatca tgatcagcaa ctccatcaag
     5881 ttatcattga ctgggctgct cgttgattga ataacataga catgcgatcc acgaatactt
     5941 tcttcaatgt ttacttgaat ttctccatca ctaaattgag taacagatga ttttcctaac
     6001 tcgacgccga ctgctgctgc aattttctct gctaatgggc gattggaatt taacgcaaaa
     6061 atttttaatc ttgggtcaaa gtaatgtttt gacatgggga cctccacttt ctttttcaca
     6121 actctagaat tctacctaat aaatagtagt catatttttt aaataaatca agtgattttg
     6181 caaaagtctt agtttagata agggagtttt tttgcatatc cttctttatt gacttgtctt
     6241 gctctcgcaa ttgccagcgc atattctgga atattgtctg taattgttga cccggcagca
     6301 atcgaactgt ttttagctac ctcgacaggt ccgatgatat tcgtgctaga accaataaag
     6361 ctgtggtcgc cgacagtcgt atgatgtttg ttctttccat catagttgac gaagacaaca
     6421 ccacatccga cattgatttc ttctcccagc gtagcatcac caacataagt caagtgaccg
     6481 actttagttc ctttgccgat ttgagcattt ttcacttcca caaagtttcc gatatggacg
     6541 ttttcgccaa tttcagcttt tggtcgtaaa tgtgcataag gtcccacatc tgcatgtttc
     6601 ttgacatggc tgctttcaat gactgagttt tcaatgacga cgtgatcctc aatcctactg
     6661 tctacgattt ttgaatgtga cccgatgaca caatcagaac caatgactgt atttccttgg
     6721 atttgtacac ctgcttcgat caatgtgtct ggaccgattt ctacgcctgc atcgatgtat
     6781 gtcgttgctg aatcgacaaa gcttacgcca ttgaccatat gcatctggtt aattcgcttt
     6841 ctcatgatct catttgcttt agctaacgcg atccgatcat tgactcccat tgattcttca
     6901 aaatcatccg tttgataagc agcaactgta tggccttctt cttttaagat ttcgatgata
     6961 tctgttagat agtattcacc ttgagcattg tttgttccaa ctttgcttaa cgcatcgaac
     7021 aaagcttcgt tgtcaaaaca gtaagttcct gtattgattt cttgtacaag agcttcttct
     7081 ggtgttgcat ctttttgttc cacgattttt tctacgatcc caatatggtc acggatgatt
     7141 cgtccatatc ctgttgggtt ttctgcttgt gccgtcaaga tcgttgcact tgcatttttt
     7201 ccttggtgat attcaaaaag attgttcagc gtttcagtag tcaataatgg tgtatcgcca
     7261 ctgataacta acgttgttcc tttttttcct tccaagaaag aagcagcttg caaaacagca
     7321 tgtcctgttc ccaattgttc tgcttgtaac gcatatttac tgcgttctcc tagttgtgct
     7381 ttaacttgtt ctgctccgtg tccaacgatc gtaatcactt catctggttt cgtttcactg
     7441 acccgattaa tgatatgttc taccataggt ttaccagaaa cgggatgtaa aactttatat
     7501 aattttgact tcatgcgggt acctttccct gccgccaaaa taattgcata acgtgcgtcc
     7561 aactgcgtca ctcctaaata tagtttgctg atttcagttt atcccagtat acccattttt
     7621 tcaacaaaac aagtgatttt cttttatccc agcgttttct ggataaaaaa atagatagac
     7681 cataacgggc ctatctattt ggtaaccggt gctctcctgc caactcctcg gtcacaagtc
     7741 acactactca taaaacatga aaagctgttt tttgaaatcg tttcttgtga cttagagtta
     7801 aacggtaggc ttacaacctc ttcattaaac gtttttcaat cagctgacct tcggtattag
     7861 ctcaataaac ggcaaaatat gaggagcaat ttttccgttt attgagctaa tactcaggac
     7921 aggacgctga tttcacaacc tctagataaa cggtgttcaa aagccagttt ctcggtatta
     7981 agccaaattt atgaaaaaat gtggaaagcc attttcacaa aatttttctt actactcgaa
     8041 actaagcagc tttttcacaa cctcttattc tgaaaaataa tttcctggca caaccgtaat
     8101 atttttcgtt tgagtatcta catctttgac ataaagcagt gacgtataat catcgatggc
     8161 gcgatgaccg ttgaattttg attcggcaaa tacagtgatg ccaacaagtt ctgattcgaa
     8221 ttcttcaatc aagctcttca ttccgttgac tgttccgccg cctttcatga aatcatccac
     8281 tacaaggaca cgtgaaccac gtttcaaact tctcttagac agttccatct tttcaattct
     8341 ttcagaagat ccagacacat agttgacact tactgttgat ccttctgtta tttttgagtc
     8401 ccggcgtaca ataacgaatg gcgcattcag ataataggac acagcttggg caataggtac
     8461 gccttttgtg gctacagtca ttacagcatc gattttttca ccaaggtatt tagaagcaat
     8521 gattcttcca acttgacgca gcagttcagg ttctcctaac aaatcagaga gataaacata
     8581 tcctcctgga agcagacggt cttgttctga tagacgttct gctagagatt caatatattt
     8641 tttcgcctct tcatatgaaa tttcagggat gaacaataca ccacctgcag cacccgggat
     8701 tgtttccaag gttccatacc ctcgttcttt aaatgttttc ttgatgattc ccaaatcttc
     8761 actgatagaa gatttagcag attcataacg ttcggcaaag cttgttaagg aaatcaattc
     8821 atgcgggtga ttcaataaat actgtgtcat gtcaactaga cgttcactgc gacgtacttt
     8881 cacctattcc aactcctttt aagaaatttt atcgttttac attatataag tttttcttca
     8941 aaaattcgag cattttatga aaaaataaga aaatagttcg gtatttatta aaataaaaag
     9001 aagcctataa aaaatttttc gtttttataa ggcttctttt ctttataatt tagttatttt
     9061 ttcttctgaa ggcaaccaat attcgtttga tgatatttac aatcaggaac aaagcaataa
     9121 agactaatgt gattgttgct cctggaggtg tatctagata aaacgagcta gttagtcctg
     9181 acagcatccc tagaaatcct acacaaacac tgatagcaat cacgacattg aagcttttgc
     9241 ctaatcgcat accgattgct gcgggaagaa ccatgattgc ggatatcaaa agtgcaccgg
     9301 caatcgggat catcacagca atagccacac cagtaatcac attgaacatc atcgacatca
     9361 aatgaacggg tagcccatcc acgtgggcgg tatcttcatc aaaagtcaga acatacatcg
     9421 gccgtttgaa taaaaagaac aatataccga tggcaacgaa taagattcct aaaaagatga
     9481 cttgctccca tgtaatggtc acgatcgaac caaacagata ggattggata cttgttgctg
     9541 aattccctcc gctcaaattc atcaatacta acgctagcgc caaaccacca gccattaaaa
     9601 tggcaatgga gatttctgaa taggttcggt agatcgttcg cagatactcc aatatcacag
     9661 ctgctaatac aacgactagc atggtcgtaa gtgtaggatt aaggttcaaa aagaatccta
     9721 acgctacccc tgctaaagag acatgagaaa gcgtatcagc catcagcgat tgtcttctga
     9781 tcactaaaaa cacacctagc atcggggcga ttccggcaat gaagatagcg gcaagaaacg
     9841 ctcttctcat gaattcatat gaaagcaacg ccattgagaa tcctcctttc tcaccagtcg
     9901 gatctgtctg tccgcatact gtttgatatc ttcatgatca tgggtgatca ttagaactga
     9961 tttcccatgg acatgcgcac tatgtcggag aagacgataa aattcatttc tggattcttc
    10021 atccatacct gttgttggtt catcaagaac aaataagtca gggtcagtag caaaaatacg
    10081 cgctaaactg attcgctgct tttgtccgcc agacaattca cctattcgcc gatttcgcat
    10141 atcccacatc cctacagctt ctaaagcacg ctgtacatgt tgatgatctt tttcagagag
    10201 acgcttgaac cagcggcctc ttggatatct tcctgaacgg actaattcga tcaccgtact
    10261 aggaaaacct gcattgaaag atgcaacttg ttgaggaata taaccgatac ttaatttttt
    10321 tccttcttga tttttctcag caatctttat cattcctttt gaaggtttca gtaatcctaa
    10381 cgatgctttc accaaggttg acttggctgc tccattttct ccagttaaaa tgacaaattc
    10441 acccgcatct acatgataag agacatcttc tagtacaggt tcatcatcat agtaaaaggt
    10501 caaatcagat atttcgatat aacgcacctt acaacctcca ttctaaaact taattgatac
    10561 tttcttttaa agctttcaga tttttttcca tgacagaaat ataattttcg cctgctttga
    10621 tttgttcatt agtcaagctt tctaaaggat tcaacacttc tagcttcact cctgtttcat
    10681 tcgacaatgt ctcagctacc ttcgaagagg cattttcttc aaaataaatc actttgatgt
    10741 tgtttttctt cacaaattct tttagctcag ctaagcgact tggtgtgggt tcctgatctg
    10801 gtgaaacgcc cgaaatcgct acttgtttta agtcgtattg attcgctaaa taagcaaaag
    10861 cagcatgctg agtgacaaat gtgcggtttg ttgcatcttt tagctcatcg gagtattttt
    10921 gatccagtgc ttcaagcttt ttgatataag catcggcatt cttcgtaaaa gtttcctttt
    10981 tatctggata tttttcgcct aattcttcag caatcgttct gacttctttt atagctaata
    11041 ccggatcgag ccaaacatgt ggatcgtatt catgtgaatg accatgccct tcttctgatt
    11101 cttcatgttc gtctgcttct tgcgattcta aacggtcgat tcctttagct gcttcgatca
    11161 tcaaggtctg tttgctatcc actgaatcct ttaacgaatc cacaaaaaat tccatgtctg
    11221 aactattata cacgaaaaca tctgcatcgg aaatttctgc tctttctttt gcacttggtt
    11281 cgaaatcatg cggctccgtt ccagcaggga tcaaaagttt cacgtttcct tcatccccta
    11341 cgatctcttt tgtaaaatca tacatcggat aaaaagtcgt aacgatcgtc aaatcctctt
    11401 ttttgtctgc ttccttgttc gtatttccac atgctgcaaa cagtaaagca cctatcatta
    11461 ccgtagctgt caaaagatat tttttcattt atatgctcct ttcaatgaac aaatcggaat
    11521 tttacgattt attaacgtga actaatgtat caaaataaaa aaacacagtc aatagaaatc
    11581 catcaatttc tgatttaagc atgtatattc ttgattaaat cgtaaaatgg atgagttgct
    11641 gctcatatct agccatttca ctacaataaa aaactgaaga ataccatttt aggattcctc
    11701 agtttttcat cacctatttt acttcttata ttttattgca gggttcgtac taaataaact
    11761 tcctcacaaa aaccttttaa cccattatat actctctgcg ctcttgaata atgttgacac
    11821 aaggcaaaaa cggttggtcc gcttccactc atcaatgcag catctgctcc gtacttgatc
    11881 atacgctctt tgatttgatg gatgactgga tgccgctttc ccgttatatc ttctaaactg
    11941 tttcccattt ttttgatcat ctgctgataa tcttgctctc ggatggcttc agcaagtccg
    12001 tggatgtctt gatgttggat ggcttgcgta tctacttctc taaacactgt acgtgtagag
    12061 acactcattc ttggtttgac caacacaacc cagcactgtg gcatagaagg taatacttgg
    12121 atttcttccc ctttgccacc gacaaatgcc gtacttccgt agacacagta aggaacatct
    12181 gtaccgactt ccaaaccgat ttctgccagt tcttctaacg aacagcccag attccataat
    12241 tggttgatcc ctcttagagc agctgcacag tctgtacttc ctccgcctaa tccagctgct
    12301 actggaatat tcttcttaac aaagatcttg acaccggttt tgatattgta tttatttttt
    12361 agcaataaag cagcttgata aacattgttc cgttcatcta ccggtaaaaa tgctttattt
    12421 gtttctacaa tgattttgtc ttctgttatt tcttcaaaaa atagatgatc tgccaagtct
    12481 acgctcgaca tcaccatttc caactcatga tacccatctt gccgtctata taatacatcc
    12541 agtcctaaat ttatcttggc tggcgctttt tcaatcaatt ccatcctctc acccattcga
    12601 aaagtctaag tcgcaagtat tctatcatag ggaaaaataa aagtatagct tatgtctgcc
    12661 tagtggttga ttttgtcatc gtttcaacag ctttcacaga attttctctt cataatccaa
    12721 acaagttcta gtgattctta taattctgtg agcacttctt ctgccaaact cggaacattt
    12781 cctttttctt ttcctatcag actgagtagc tgcatggtag caaatccgaa attacttcct
    12841 ttcctataag caaaataacg tccttcccaa tgatcgacat attttaattt cttttcataa
    12901 gcagactgga aggaatagaa aaaattacca taattatata cgatatgcat gactttttct
    12961 tgaaagaaag aaaaatctgt ttctccaaca ttagctaatg gagctaagcc tagattggct
    13021 tccgagtagc ccattttctc gtatacaata aacagattgg ctaacagata gtcagctaat
    13081 tcctcagatt ctttaggtaa gacccgcaac aaatcatatc ccgcctgctt cttcgtcatc
    13141 ggctgagcgg tgatgaagcc aacgactttt tgatctttac ggacaatacc gacaccgcta
    13201 gataatacat atgatttatc aaatcgtccc acagagaagt atttttctcg tgcaccttga
    13261 agccattttt gtgaaacttc atttacagct tgatgtaatt cttccggcag ttgatcgtac
    13321 caagtaaaat ggtatccttc tttcatcaaa cgttgatatt caagttgctg actcagccga
    13381 gacaagtctt ctgttgctag atcaacaatc cctgcttcac ctactttcgt gaagtgaaaa
    13441 cccaattcat gaagcatcac tacgtagctt tctgatatct tataaaacgc aagctgatag
    13501 cctaaacaat ctgcttgttt cataaactga ttcgttgctg cccgcatcat tttaggattg
    13561 ccaactggat ctcctaaaac aaagcatttg tttcctttga tctgataacc aaaaacgact
    13621 tgatcttggt cgtcttcttg gtaataaaaa taactgtaac ctgacaagcg aagctgatgg
    13681 cttgtagctg tgcctccgta tgtttccaat aaacggtcaa aacggtcttt ttcgtactca
    13741 ctgccaagct tcgtagtatc ttcagctaaa tattgataaa gcgccactaa agctagcaat
    13801 gagatgccca aaccaataag ccctgagaac cacacatcat ctgaaggaaa caaaataaaa
    13861 tgatttcctg ttattcgacc gactaaaaag cgtccgctgt gatagcctgc aattgcgtaa
    13921 acgataaaca aaaagccgaa caagctagca tcaaagatta tagctcccca agaataaacg
    13981 aattttgttc gataaaattc ttttctggat aaccacacag ctaacagaat caagacatat
    14041 accaatatca actgccaaga taacgtacgt gtgattgtat ttaaaatacc aaaagatagt
    14101 aaagcaatcg taggcagaaa tgcctttttg acttttactg aaagtgctct agcaaggccg
    14161 agtaataaaa agccaaccaa tagattcact gtctgatcta aaaaattgaa tgagaacggc
    14221 aataatactt gaaatagccg actgattgca gacagattag tgattgttga tagaagtacc
    14281 atcatgatcc ccgcaaaata gacagcactt acgagcacga tatgcgcaac cttttggaaa
    14341 aacagtcgcg gaatgttatc taaaaatcga ttgattttga ctcctgtatg tgtgatgaac
    14401 aatagaagtc ccgtcataaa aggtagaaca taataaaaca accgataata taatagccaa
    14461 actactgcta catcttgccg aacaggcaat tgactcattc ctaagatcat caaaacgtca
    14521 aaagtcccca ttccacctgg gaccatcgtc agcattccta tcaatgtagc aatcatgaac
    14581 ataggataga tcgaaagcat cgaaatatct attctcatca acttgccgat gatcaaaaat
    14641 accgcaaggg ctcccgtcca ttgtccaaag gatgccagta gcagaccaag caagcctttt
    14701 ggataaaact cgaagaacaa tgtctttctc tttagataag caaaaaagaa aatgactggt
    14761 gctaaaaaac taccgccgaa aagccagatc caatagcttc gaaaaatact ttctgactga
    14821 ataaaaaaga catcaataaa tgtaagaaac gaccatacag acaaaccagt cagcataaat
    14881 agtgcgactt ttgatacagt ggctaaaacc atttttctat ttgtctgctt tccataaaaa
    14941 ctagcccgca gacttgctcc taccacacca ccaaaaccgg cgagattgtt gatcgtgttt
    15001 gttacccacg cagcaagaag aaactctttt ctttccattt ttggttttcc ttgtttttct
    15061 aagactctga tcgtcaccca atcatacaac aacatcggag tgacacccag cagtccagcc
    15121 agaatcatga gcaggatcgt catgcggctt tgttgtccca tcctttgcca aatatcttgc
    15181 caactcatgc cattagcaat atttgcgact tgatttgcca caaagactaa cacggagccg
    15241 aaaaaaatca gttttaaaat cagactatgt tcctttatcc attgcagcat caagtatcgt
    15301 ttatttttca cattttccca ttcctaactt gtatactttt gtgtcatacc ccaatgttat
    15361 cttatttatt ttaatttttc cactttagac ctgttctttg cttgcgatga tagaaaaaga
    15421 aagatatcct aatgctaaag gagaggataa catgaaagta ggatttatcg gcacagggaa
    15481 tatggcacaa gctattattg atggtttatt aaaaaaagga acagtctcga aagaagaggt
    15541 gttcgtttcc agtggacatt ttgaaaatgc acaaaaattt gctgctgaaa ctggcgtcca
    15601 tgcatgcaaa agtaatcagg aagttgcatc acaatcagat atcgttcttt tagccgtgaa
    15661 accaaaaatc attgaaaaag tattggaaga actaagagaa tatagccaga aagtcttatt
    15721 catttctatt gcttcaggaa aatcattaac agatttagaa acagcgcttg aagatcctca
    15781 ggcctccatc gtacgtgtga tgccgaatgt caatgtcagc gtaggagcag gcgtttctgc
    15841 gatttgcaaa aatgaagctg ccacggagga acagcttcag caagctacga tgatttttga
    15901 agcaatcggc agcgtctatc ctttagcaga atcagatttc agtacattca ttggccttgc
    15961 tggcagctca cccgcattcg tttacatgct gatcgatgcg atgggacgga ctggtgtact
    16021 gaatggtttg tccaaacaga cagccactga gattgctgca aaagcaatta tgggttcttg
    16081 tcaaaaattc ctttcaagtg ataaaaatcc atgggaactt gtagaccaag tttcttctcc
    16141 tggcggtaca actgttgcag gtgtagttgc cttagaagaa gcaggattca tcccagcaat
    16201 catcaaagga atcaatacga cgatcgagaa agatcttgag atgttgaata aaaaataatg
    16261 atagcaatgt tttttcgtgc cttacaaaaa aagaagagct gtggcttttg ccgcggctct
    16321 tcttttgtat tttttattat ttagcataat cagttgcacg agtttcccga ataacgatta
    16381 ctttgatgtg tccaggataa tccagttctt cttcgattcg tttacgaata tcacgtacta
    16441 aacgaacagc gtctaaatcc gagatttctt ctggcttgac cattacccga acttcgcgtc
    16501 cagcttgaac tgcgtaactt gattctacac cggcgaagct gttcgaaata ttttccagac
    16561 ttcttaaacg acggatgtag ttttctaatg attcacttcg cgcaccaggt cttgctgctg
    16621 agagcgcatc tgctgcagct acaaggacag agataacaga agtagcttcc acatctccat
    16681 gatgagaagc gatcgcgttg attactactg ggttttcttt gtacttggca gctaattccg
    16741 caccgatctc aacgtgagat ccttcaatct catggtcaag tgctttccca atatcatgga
    16801 gcaacccggc acgttttgct aattggatat cttcgccaag ctctgctgct aagataccag
    16861 ctaattttgc aacctcgacc gaatgcttca agacgttttg tccataacta gttctgaatc
    16921 gcagacgtcc gatgatcttg attagatctg gatgaagtgt atgagcaccg acttcaaacg
    16981 ctgcctcttc cccgtattcg cgaatacgtt catccatttc tttacgagat ttctcgacca
    17041 tttcttcgat acgcgctgga tggattcgtc catcttgtat cagtttttcc aaggtcatcc
    17101 gtgcgatttc tcttcggatt ggatcgaatc cggaaagaac aactgcttcc ggtgtatcat
    17161 cgatgattaa atcgatacca gtcagcgtct caagcgttcg aatattacga ccttctcgtc
    17221 caatgatacg acctttcatt tcatcattcg gaagggtaac gactgaaaca gtcgtttctg
    17281 aaacttgatc tgctgcgcag cgttgaatcg ctaatgataa taagtttttc gctttgcgat
    17341 ctgcttcttc tttggcacgc tgttcagatt cttttaccat tagagttaac tcatgattca
    17401 gctcttcttc agtcgatttc atgatgacat ctcgtgcgtc ctcttttgat aaaccagcaa
    17461 ttttttctag ttctttttgt tgatcttcaa tcattttttc aacgtctttt tctcgctctt
    17521 caattaattg ctgttttgaa ctaagtgctt cttctttact ttcaagtgag ttctcgcgtt
    17581 tttctaacga gtcatcttta cgattcagcg tttgttcgcg ttgaatcaaa cgattctctt
    17641 gagattttaa ttctaactta ctttctctca gctcactttc aacttcagaa cggtatttct
    17701 gattttcttc cttagcttct aacaatgctt ctttttttag agtttctgct tctttttttg
    17761 cactatcgat gattccagca gctgatgatt gtgcaccagc tatttctttc tcgtgacgtg
    17821 actttgcgac cataaaccct aaaccaagac cgacaattaa accgatgata gcgaggagaa
    17881 tgttgaatac cataaaatcc acctccatac tatctttttc atttttatca tctatacagc
    17941 ttctatgata aattattcta aactcgtcaa tatgcatctt cgcatatatg tgtacaaaaa
    18001 acatgcacaa ctttattcta atgtttgtac cccgtagtgt caactttaaa taaacaaaga
    18061 aacggctttc tacttattca ttaaacgatg gtttttaaaa taaatgacac tagtttcata
    18121 taggtaaacc tttaaattga gaaacttttc tattaaatta ttctttgtag atgaacagat
    18181 atttttattt tatgtaccca ctcgtataat taaataactc acgatttctt tattcaataa
    18241 aaaaacggca ggtcaaggag agtacctact cttcagacca gccgtttttg tttatcataa
    18301 tttttattct tctactaaag gcaattcttc ttgtcctttt tcatcttctg ggacagcgac
    18361 ttcttcacca ataccataag ctgctctaac tagagcagaa acttctgcca tcatttcagg
    18421 atgattagcc atatagattt tagcgttttc ccgtccttga ccaatccgat cttctttata
    18481 agaataccaa gcaccgcttt tatcaacaat gtctttttct actgccatgt ctagaagttc
    18541 tccttcttgt gagatcccta aaccatacat gacatctact tcagcgattt tgaaaggagg
    18601 tgctactttg ttttttacga ctttgatctt tgtacggtta ccaacaatat ctgtaccttg
    18661 tttcaattgt tctgcacgac gtacttccaa acggatcgtt gcgtagaatt tcaatgcgcg
    18721 tcctccagga gtgatttctg gattcccaaa catcacgcct actttttcac ggatttggtt
    18781 gatgaaaata gcgattgttt ttgttttgtt gatcgaacca gagagtttac gcaatgcttg
    18841 agacatcaaa cgtgcttgta acccgacatg tgagtcaccc atttcgccgt cgatttctgc
    18901 tcgtggaact aaagcagcaa ctgaatcgac tactacgata tctacagccc cacttgatac
    18961 taaagcatca gcgatctcta gaccttgttc tcctgtgtca ggctgtgaaa gaagtagttc
    19021 atcgatattc acacctaatt tttgtgcata ttgcggatct aacgcatgct cagcatcaat
    19081 gaaagcggcc gttccgccat ttttttgtac ttctgcaata gcgtgtagtg caactgttgt
    19141 tttacctgaa ctttcaggtc catatacttc gatgatacgt ccacgggggt aaccgccgac
    19201 acctaaagcg acatctaacg caagagagcc acttggaatt gtagagattt gttggtcgat
    19261 tttttcgccc aatttcataa tagagccttt accatagctc ttttcaattt ttttcagtgc
    19321 agcatctaag gctgctttac gatcatctgc caatacgata atcctcctta tatttacaaa
    19381 tcagagcaac atttcattat ccttatcata tcttttttag tgaaaaaaag caagaaaaaa
    19441 ccgaacaaat attcgcattt atcattttct taaaagctgt tttctcaaaa gatcaaatcc
    19501 ttgcataacc gcattatatc tgatagcagc acgatctctg gcaaagtgat atttttccga
    19561 aaccacgccg tctttagatg aaatagcgat ccatactgtt cctgcagatt gaccttctaa
    19621 cgtgtccggt ccagccactc cggtgaaagc tacactgtaa tctgttcttg ctatctcacg
    19681 tgcttgaatg gccatctgct ccacacattc tttgctgact gttccatatt ctgctaatag
    19741 ctccggatca atctccagaa aaccagcttt tgtttggagc gagtaggtaa cgaatccgcc
    19801 tggaaatact tcagatacac cagcaatgtc gcctaatgcg gcttggaagg cgccggctgt
    19861 caaactttcc gctgctgtta cagtctgctt gttttctttc agtagttcca ctacgacttt
    19921 tgctagcgaa ttatcatcgc cgtatccata aaaatattcc cctactcgtt cttggatttt
    19981 ttcttctaat gctaaaagag cttgattccc tgcctgaaca tcatttgttt tcactgtcag
    20041 tcgtaatgtc acttcatttg gtttggcata tggtgcgatc gttggattga tctgtgtctc
    20101 aatcagatct tttagctcag tgaccagtcg cgattcacca atcccataaa agcgcaaaac
    20161 tttagaaatt agtttttctt cagaaggaaa acgttcctct agtaaaggac gtacttgttc
    20221 cacaaacatt ggtttcaact cattaggcgg accgggaaga aggatatacg catgtgtatc
    20281 tgtttgataa aaagtcccta aagcaagccc tgtacgattt ggtagaggaa ccccgccttc
    20341 gataatctgg gactgttgca gattgttttt ggtcattttt cgatgggttg tttcaaaata
    20401 tgccaataat tttttgtatc cttccgtatt ttgtatgaga gacttaccga ggtgagccgc
    20461 agttgcttct tttgtcaggt catcttctgt cggtcctaat ccgccacata agagtatgag
    20521 ttcacttctt gtttcagcta gagcaatcaa ctcttctaaa cgctgctgat tatctcctac
    20581 aactgtttga taataaactt cgatacctag atcagctagc tgttctgaca agaaagtggc
    20641 attcgtattc acgacttgtc ctagtaaaag ttctgttccg acagctatta tttctgcttt
    20701 cattacttcc cgctccctta tatagtatac gctgtatttt tatatttttt tatttaaaaa
    20761 gagggcaagg agctgtgaca aaaatcttgt cacagctcct tgttccaaat aaacagtgtt
    20821 ctcctgccaa aacctcggtc ataagtcaca atatacataa aacatgaaaa gctgtttttt
    20881 gaaattatcc cttgtgactc agagttagac ggcaggctca caacctctcc actaaacgat
    20941 acttacattg atcctttgaa cacaccgctg tttttgatga agtaatccac acctgaatag
    21001 atagtaaaga tcagacaagc ataaagcatg atttgatcta ctggaatacc gatcaggctg
    21061 aatgggatat tattgataaa cagcaagata atagcaacca tttgtgtagc cgtcttgact
    21121 tttcccggcc aagctgcagc catgacttct ccatgttcga caagtagtaa acgcaagcct
    21181 gtgacggcta attcacgaca gacaatgatc gctactaccc aaccaggggc ctttccttgg
    21241 tcaaccaaca tgataaaagc agtcataact agcattttat ctgccaacgg gtccgcaaac
    21301 ttgccaaaat tagtgacaag gcctcgcgca cgggcaattt ttccatctaa ccagtctgtg
    21361 atactagcta aagcaaaaat aactgcacct actagctgtg tgacagccag tgtggtgtct
    21421 cctacgttaa attgtcccca atctaaaggt aaacctacaa ccaaaatgaa aatcgggatc
    21481 atacaaattc taagtacagt taatttattt ggtaaattca cactatcgac tcctttcttc
    21541 cctattctac gtgactatca gcgaagtttc caccgatatt atttactttt ccaaatgaat
    21601 ttattcaaag gagtattttt attgaaattg atctttttga attaacgaag aaggaccgcg
    21661 acacagattt gtcacgatcc ttctttttta tacctacaag taaacagatg cgtaaactaa
    21721 tttatacgat cattctgcgt attgaagagt aaggttcaca ttttttggac tctgattgtt
    21781 ttcccctgga ttaactggta cggattctcc attcgctttg atcgttgcat tgcttgctgc
    21841 accaatcgtg atggtcgcat ttgttgctgt ttccggtaac acggtactct gtgtttcatt
    21901 tgctgccagt gtcccttgat aaacataggc attgtctact agcacaccta accatacacg
    21961 attgacagca gtaaattcaa gggttacagg cttggtagcg tctgtgatat ttactgcgat
    22021 ggcactgcca gaatcttctc ctgtagctat tgccattttc ttttcttcac ttgattttgt
    22081 tgttgattct actgtagaag actctttggt ctgcgtgctt tgctctgagg aagaggactc
    22141 ctcgactgat ccttctactt taagcgaaga agctgtgtct ccgattattg gatcagcttg
    22201 acgatcttgc caagtcatat agcccacgac aacgacaatc gccaaagcaa ccaatcctaa
    22261 taaaatgaca ggaagacttg tccaaaagcg acttggatgc gattcttcct gatgcattgc
    22321 ttttctagaa gtacttactg tttcaggctg cggacgttca gggaccgatc ctgtcaattt
    22381 gcttttccca tcaaaaacat cgactaaatg gtctccatct tctcctacag cttcagcgta
    22441 ttgccgaata aatgcccgca cgtaaaattt accaggcaat tggtcaaaat catcattgtc
    22501 gattgcttcc aaataacgtt tttgaatttt tgtaatctgc tgtaattcat ctaaagatat
    22561 ttttttattc aggcgtgctt gccgtaattt ttctccgatg gtttcaaaag ccactcgttc
    22621 atcttctcca gtctgtttga ttctccgaag catctgctgt tgcaacgaaa gacgttatgt
    22681 ttgggtgctg tgacaaaagt catgtcacag ctcctttttt ccgaataaac attgttctcc
    22741 tgccaactcc tcggtcacaa gtcacaatat ccaataaata taagaagctg ttttttgaac
    22801 ttgttccttg tgactcggag ttaaacggca ggctcacgac ctctttctta aacggtgttc
    22861 aatcagctgt tcctcggtat tagctcaaaa accggcaaaa tataaggaga tatttttccg
    22921 tatgtttctc taatactcag gtcaaaacgc tgatttcaca acctcttcct taaacggtgt
    22981 tcaaaagctt gcatctgcgg taataagtcc aaccaagtta aaaacattaa gaagctgttt
    23041 ttacttggct gttcttatta cttgatgcag ggcagctttt tcacaacctc ttggtacacg
    23101 gtgttccaga agtagcttct tcggcaataa gccgaaatat cacaaaaatt tgagaagcaa
    23161 ttttcgtaaa ttccttctta tttcttgaag ctgaccactt ctgtcacaac ctctttgatt
    23221 acttcgtttg attttatttt aatataagtt gattaaaaga gagcatgatt tgttttattt
    23281 tctcactaat ttttccaaca caactaagaa taccataaaa gctgattttg gaggaggttc
    23341 ctactacaag tctaaaacga aatttaagac ttttcctcat aaatactggt ttattttggt
    23401 ctcatgtaaa actcgctgaa ggcctcttca cttataaatg cttccccagc tgccagtacg
    23461 tctttcattt ggatcgaatc gatgatttca ggaagatcaa ataaagttcg atcgccaaat
    23521 aaactttgcg taaattgatt ggcaatatat tcgatcgaat ttaatgattg gaaatattgt
    23581 ccaagcattt tcttcttcag caaatcgaga tttgtttctg acacttccgg atcatcagcg
    23641 aatccaagaa tgatttcttt gactttttct gctgctttct ctggttcgtc cgtatctccg
    23701 ctgaagtccg caaagtgaaa ttcacgatcc aagctgaatt caaaaccaaa gctgtcatcg
    23761 ataattcctt gattgtacat cgctagatag tttcgagaag tattgcctaa aatcatttgg
    23821 aacaacagat tgattgctgt tttatagcgt aacagttctg ttccttcttg cggcaatgtg
    23881 tctaatcctt taataccaag tacaaattta tctcgtgtaa tggctgcttc caatgcactt
    23941 tgtttgatga tttcttttgt gttttcaggg aaataacgta caatttcttg ctttggaggg
    24001 aaattttttg cttcttggtt ttcccgaata agtttcatca atttctcagg ctccatctta
    24061 ccaactacaa ataaaaccat attgcttggc tgataaaacg tccgatagca cgtatacaag
    24121 tcttgagctg tgattttgtc gatactttca accgtgcccg caatatcgat atgcaatggg
    24181 tgtgtaggat acaagttatt tagtatgcca aaaaacatcc gccagttagg gtcgtcttca
    24241 tacatttgga tttcctgacc gatgattcct ttttccttgt ttacagtttc ttctgtgaag
    24301 taaggtgctt gtacaaaatc gatcagagtc gtcagattct tttctacctg atccgtcgta
    24361 gaaaacagat agctggtttt cgtaaaactt gtgaaagcat tggcggaagc tccttgtttc
    24421 ccaaataatt gaaagacatc accatcttct ttttcaaaca acttatgttc taaaaaatgg
    24481 gcaattccat ctggaacttt caccttttct ttttcaccat agggaataaa ttcgttatcg
    24541 atcgaaccat aattcgtact gaacaaacca tatgtcttgt gatagtcatt tttaggcaac
    24601 aaatacacgg tcaaaccgtt tggcagtact tcatgataaa gtgtttcatt gatttgctca
    24661 tattctgttt tattcatttg catttcctcc tgctaaaaag aagattgcct gcaattcgat
    24721 ttgctcagct acttgttgta tctctttgat cgttacgctc tccatacgtt tcaaccattc
    24781 ttcatcagat aattttgttt ccggcagcca gctgtccaaa aaagaagctt cgattgccgc
    24841 ttgcggagag tctagagaaa gcagatattg gtttctcagc attgcttttg tctgagacag
    24901 ttccaactct gttatttcac catttcgcaa actttctaat tgctcgtgaa tcagatgaag
    24961 tacttgattt cggttctttt catcgatacc ggtttggaca ctcatgaatc ctcggaacgt
    25021 atccacgcta ctagaggcat aataagctag actttctttc tctctgacat tcatgaaaag
    25081 tttagagtga ggaaaaccgc caaataaacc gttaaagacc attagcgcaa aacgttctgg
    25141 ttcatcgtaa tacacatttg tctgataagc taggttcagc tttgcttgaa cgattggctc
    25201 acgtacttgt cgttccttca cgatattcac ttgaggttgg gtataaaaca gatctggata
    25261 aactgtttcc cgcgactcaa atggtaattg cccaactgct tcagctgctt tgtccggatc
    25321 aacatcgccg acaacaaaaa tgtcgatttg atcatttgcc atcatttctt gatagtagga
    25381 cgctagcgaa ctagcagtga tcttgtccaa atcttcgact acgcccaacc ctgggatctt
    25441 ttgttccggg ctgttttcaa aataaagttc ttgcaaggca taggaagcaa aagtttgttt
    25501 atcttccttc aaactttcca aatatagacg cagattgttc ttttccaagt caaacgtcaa
    25561 ctgatcaaac tgatgatttt taatatttgg ataaaataaa acctctttta aaaaatctac
    25621 cgcttgagaa aaaaggtttg gatcattgac atattcacca ttcacaaaac tgatccctgc
    25681 gtttagccaa tgtaaatttc ctttttttct aactgataat ccaaagcttg cgccataaag
    25741 ctctgcaagt tgcgcactta actttgtctg atccggataa ttcaaactat ttgtttccaa
    25801 catgctgctg agaagtgaac gtttcgtgat gacttcttgt tgcagacgcg cagtaaaacg
    25861 gataaaaatc cggatcgttt tgtattgttt tgttggtaag acatgaagat tcacgccttc
    25921 tgccaattga tacaccatat ttatatgctc cttttcacag ttgattgccc gcttactctt
    25981 ttaatgggtc aacctgcctt ttttacttat tcctctgctt gaaatttata agttcaggca
    26041 attcgccgtt ttttctaaat gatgttacac tttatagtat agcatagatg ttttttatca
    26101 aaagaaacag acggctaaaa gcgtatattg tttttttatt ttttattttt cgatatacta
    26161 aagacaaata aaagaaggga gggtcattca tgatcaaaga attcaaagag ttcatcatgc
    26221 gtggagatgt cttggatctt gctgtcggcg ttgttattgg tagtgcgttt acaagcatcg
    26281 taaaccaagt ggtgcaaggc ttgatcacac cactaatagg ttggtttgtc gcaatgatca
    26341 caggtacttc tgatttagaa ggagcacttt caattcttga ctggtcgccg acaaaaggcg
    26401 tcacatttgc gtttggtaac gttattagtg ctatcattac atttctgatc actggttttg
    26461 tcttattctt agttgtcaaa gcggcaaacc gtgcgaagaa tttacgctcc aaagaagagc
    26521 aagtggaagt ggaagaaact cctactgcag aagattatct tagtgacata cgcgatcttc
    26581 ttgccaaaca agtggcagaa gacaatacac atccagtaga gcaaacaaat ctttccgata
    26641 cttctaaata ataaagaatc taaaaaaaag aaagccgatt ttcagtgtcg gctttctttt
    26701 tttagattct taacttgcta cttgttcctt tttcatgtcg atatgtggaa tatcatcttc
    26761 caaatacaca tctgagattg ccttgaatcc aaacgactca taaaaagctt gtaggtattc
    26821 ttgtgcgccg atcacgattg gtttttctgg aaaatttttc tggatcatgt taatcgtttc
    26881 ttgaacaatc tttcttccta aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc
    26941 aaaatggata ctctccgctt cttcatatac tcgcgtgtag gcaaggatct tcccatcagt
    27001 atcttgaaaa aacgtatgcc aagcttgtcc atcaatgtca tcaacttctt gataaggaca
    27061 ctgttgttcc acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt
    27121 tgacaattct tcaaatttct ttacctgata ttccactaag caaacgcccc ctgctttttt
    27181 attcttagca taccgattcg cacacaaaaa agcaaacgaa ccttacgaat
//
LOCUS       DAIGWC010000037        26160 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.037, whole genome shotgun sequence.
ACCESSION   DAIGWC010000037 DAIGWC010000000
VERSION     DAIGWC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.037"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="NOB74_001568"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="NOB74_001568"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HCI1220761.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="NOB74_001569"
     CDS             1286..2461
                     /locus_tag="NOB74_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI1220762.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="NOB74_001570"
     CDS             2465..3106
                     /locus_tag="NOB74_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220763.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="NOB74_001571"
     CDS             3103..4020
                     /locus_tag="NOB74_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1220764.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="NOB74_001572"
     CDS             4017..4688
                     /locus_tag="NOB74_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1220765.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="NOB74_001573"
     CDS             complement(5229..5717)
                     /locus_tag="NOB74_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HCI1220766.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="NOB74_001574"
     CDS             complement(5918..6184)
                     /locus_tag="NOB74_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCI1220767.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="NOB74_001575"
     CDS             complement(6184..6447)
                     /locus_tag="NOB74_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI1220768.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            6923..7108
                     /locus_tag="NOB74_001576"
     CDS             6923..7108
                     /locus_tag="NOB74_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1220769.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7250..9073)
                     /locus_tag="NOB74_001577"
     CDS             complement(7250..9073)
                     /locus_tag="NOB74_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HCI1220770.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9671..12376)
                     /locus_tag="NOB74_001578"
     CDS             complement(9671..12376)
                     /locus_tag="NOB74_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HCI1220771.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12682..13629)
                     /locus_tag="NOB74_001579"
     CDS             complement(12682..13629)
                     /locus_tag="NOB74_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HCI1220772.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13819..14088
                     /gene="rpsN"
                     /locus_tag="NOB74_001580"
     CDS             13819..14088
                     /gene="rpsN"
                     /locus_tag="NOB74_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCI1220773.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14264..14626)
                     /locus_tag="NOB74_001581"
     CDS             complement(14264..14626)
                     /locus_tag="NOB74_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI1220774.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14637..15758)
                     /locus_tag="NOB74_001582"
     CDS             complement(14637..15758)
                     /locus_tag="NOB74_001582"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCI1220775.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15774..16124)
                     /locus_tag="NOB74_001583"
     CDS             complement(15774..16124)
                     /locus_tag="NOB74_001583"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HCI1220776.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16254..17765)
                     /locus_tag="NOB74_001584"
     CDS             complement(16254..17765)
                     /locus_tag="NOB74_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI1220777.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18087..19439)
                     /locus_tag="NOB74_001585"
     CDS             complement(18087..19439)
                     /locus_tag="NOB74_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HCI1220778.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19592..20668)
                     /locus_tag="NOB74_001586"
     CDS             complement(19592..20668)
                     /locus_tag="NOB74_001586"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCI1220779.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20864..22609
                     /locus_tag="NOB74_001587"
     CDS             20864..22609
                     /locus_tag="NOB74_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HCI1220780.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22889..23326)
                     /locus_tag="NOB74_001588"
     CDS             complement(22889..23326)
                     /locus_tag="NOB74_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HCI1220781.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23310..24683)
                     /locus_tag="NOB74_001589"
     CDS             complement(23310..24683)
                     /locus_tag="NOB74_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220782.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25005..25493)
                     /locus_tag="NOB74_001590"
     CDS             complement(25005..25493)
                     /locus_tag="NOB74_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1220783.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25515..26117)
                     /locus_tag="NOB74_001591"
     CDS             complement(25515..26117)
                     /locus_tag="NOB74_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI1220784.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7503 a         5561 c         4838 g         8258 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat cgggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aacatttttt tatgggcttt ttctttgaat tctataataa aaggatagaa
     9301 cttgacttag aaaatcaagt tctatccttt ttgatatctt aacttttgga agagagatgt
     9361 aaggctgctt tctacccatc attcttacta ctcgaagcat agcgcagttg tcacaacctc
     9421 ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa gcccaaccaa attaaaaaca
     9481 taagaagctg tttttatttg gtcgttctta ttacttgatg cagagcagct tttttacaac
     9541 ctcttggtac acggtgttca atcagctgac cctcggtatt agctcaaaaa aacggcaaaa
     9601 tatgaggaac tatttttcca tttttttctc taatactcag gtcaaaacac tgatttcaca
     9661 acctcttttt ttaatgaaaa atatggctct catgcgccgc ttctttgaat ttcgtcattt
     9721 tttcttcgat gaacggatag attgccgttc ctacgattcc aaagacaaca aacaaaccga
     9781 tcatgatcca gattgctttc gtagcatttg gccaataaat tcctcctgca gattcccgta
     9841 acaagtttac cgcatgagta aatggcaaga acggattgat catttggaag aatttccctg
     9901 agacttggat cggatagttc ccgcctccgc cagagatcga cagtactaag atgataatag
     9961 cgatcccttt accgacatta tcgaataatg cagccaagac atagacgatc atcatgaacg
    10021 ctaaggcgat caagacagca aatgacacgc tgtagaccgg attttggaca tctactccta
    10081 gtaagaaaat attccctaat gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg
    10141 tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta
    10201 aatagtattc tgtcgtagca acacttgaaa gaagaacagc gccgacccac agacatagtg
    10261 cagtataaaa cggggtgcta gctgaaccgt tatttgcgat tggataaagc gcattggttt
    10321 gtagctcaac aggttgtgta aagaagtcac tttcttttgt tgcgtctagt ttcaataatt
    10381 tgatgacttc gcctagatcg acttcttgtt cgccttttcg gatcgcgtct gctgcttttt
    10441 ggataccagc tttgatattt ggccagtcat tgttgatcaa gtccgcagca gcgttcacag
    10501 ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa tgtaccggtg atttcatttt
    10561 ttagtgctgg ccaatcattt tggataaaat cagcggccaa tcctaatttt tgctgaatga
    10621 tcggtaattc attgttgtat aggtctgccc cttcattgat gccattgacg atggtatcca
    10681 tatttccatt cagcattgta ttggcatcat ggatttcttg tccaattgca ggcatttctt
    10741 tttgatattt ttctaaaatt gccactgcat tcgttacagt tgctttcgtt gagctgagaa
    10801 gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat
    10861 cgatgacttg gtctagtaga gaagtgacag tggaactgat ttgacctgta ttgataccag
    10921 caatgatgcc attgatatta ttaacaacgg catcaatttg atctagcaat tcatcaatag
    10981 ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga taggcggttt tgcagattgc
    11041 ttagcaaggg ttttaattga tttagctgat caataattgg ctgtaatttc gtatttccag
    11101 cacttgtttg caatttagtc aggaactcga ccagtttatc gattgcattt tgttgttgag
    11161 atattccgtc aataaagccg ttcaatacat tgctgatgtt tttcttttca tcatcagtca
    11221 gcttaccatc ttcaatagct gttcttacag tatctattaa cgaacctgtc gttgttgcca
    11281 cttgtccaat tgacttcaat gtaacatcta cactgtttgt gatgcttggt atcgcatctt
    11341 tcagctgaga ggcacctgat tttgtttggt ttgctagatc acttgcctga ttttctaaat
    11401 ttttcacatc tggcaagata tcttgtactt gttggatgat cgtcaagcct tgttttgctt
    11461 catcgattcc ttggttcatt gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta
    11521 gttgcttacc ggcattttgg atctctggga ttttttcttg caaatcaagg atgatttttg
    11581 cttgatcttt caactcaggc attttgtcat tcaatgcaac gactttttca cccatctcat
    11641 ctactttagg gatgtaatcc acgaattcat ttgctttatt cagtttttcc ttgatttcag
    11701 gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt
    11761 catctgttga taaaatcata tctttaactt tattgatact tactaggttc gtatcgatgt
    11821 cgtaacctat ctcattgaat actttcaata aagtcgaact ggctgttttg ataaattcat
    11881 ttgtgatttg cgattggatc gaacttgctc ctttatcggt gattttcggt gcaatcgcat
    11941 tgattttttc atttaccgta tattcgattt ttggtttctt gatatcacca ctagtaaaac
    12001 tcagcagatc ttctgagaaa tcctttggca agtaaatacc tgcgtaatac tttccggaac
    12061 ggactccgtc ttctaattgt tcttttgaat caacgaattg ccatcctaat tgtttatttt
    12121 tatgaagcga ttcgatgact tgctccccaa tggccacttc tttaccttga aactctgctg
    12181 gcttgtctgc actgtaaaca gcaattggca gctctccagt atttccatat ggatcccata
    12241 atgctttgat gttaaaccac gcatatagcg aagggatgat catgatcgcg atgatcagaa
    12301 gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag caaatataat cgaagcgtat
    12361 ttttgattga ctgcatagtt ctcccccttc ttcttttttc agctgaatta ctttaccatg
    12421 tatttcatac ttttttcaat cggctttttt caaaaaagtc gaatttttgg acatatcacg
    12481 gcaattgtct cattgtaatc tcttacatat tgagaaataa ttaaggatta cagcctttac
    12541 tttatcatga aataaaaggg aaagataatt ttatgccaaa gtttttatct attatacgta
    12601 tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac aaaaatgttt cagctttttt
    12661 cgttttttat tcctgtattt cttatttttc gaatgacagg atgattttcc cagcaggagg
    12721 atgtccttca actagctgat gtgcttggat gacatgctta agtgaagcag acagattcat
    12781 tgaaataaaa acatgaaagg ctcctttttg gtaggctttg attatgccag caaaggcttc
    12841 tgcatctaga tattcctttc ttggaacaaa cgattcataa aagccttcct ttttttgccg
    12901 caaatctaga tctgggaggt catttaatgc aacatacctg ccgcctggtt tcatgatctg
    12961 gatgccggtt tctcctttga tacttccttt cgtcgcatcg attacaaggt ctgcctgatc
    13021 agcaaattgc agacctggat ttgttttatc ataagcagca aatgctgaag ctcctaattt
    13081 ttttaccttt tcctcatttt tactggatgc actggttaag attcggattc ccttttcatg
    13141 gagaagctgg atcagacttg acccgaccgc acctgatgct cctagtatca ttacagtatc
    13201 tgtcggctgg atttccgtca aatggttgat tagattataa gccgtaattc ctggcgtgac
    13261 cattccggct gcttcttccc aactcatttt atctggaatt tttgctactt ttgctgatgg
    13321 caacacgact tcttctccgt aagtcccgcc gactgcatgg acagctactc gatcacctac
    13381 atgaacagtt gtgacatctg aaccaatctc tgtcacaata ccagcgccat cattacctgg
    13441 tacataaggg aatttcaatg ttcgtatctc tttcatttct cctaaacgca aggcaacatc
    13501 ataaggattc acactgaatg cttttatttc tacacgaaca tgtccagaac cgacttctct
    13561 gggatgagca tcgatttctt caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa
    13621 tcttcgcatg gtcaccatct ccctttttct ttaagtttac gtttatgcct ttattttgac
    13681 aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca aaatagttgt cttttttcgc
    13741 gtaacgtgtt aaattattta tctaaaagcg taaagattac gatttacgct aataaaaaat
    13801 aattggagga atttgttgat ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa
    13861 gaaacgattg aacgctatgc tgctttacgc caggaattaa aagcgcaaaa agattacgaa
    13921 ggcttgcgta aacttccttt agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc
    13981 gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa
    14041 ttagcacata aaggtttgat tccaggagta aaaaaagcca gctggtaatc caagtctggc
    14101 tgtaatgtaa aggaggaggg cgcatggacc actccttgga tcatcaaaaa agatacgttc
    14161 gcttcttcta gcagaaatgc tggtactaga agcagacgta tcttttttta cgcacagctg
    14221 gtcctttttt atatgtaaag gctgcatggt tacttcgcta tatttattta gtaacaggag
    14281 tcagtgcttc gatacccaca ctaattttca atgctcggtc aacttctgcc ataatgggtc
    14341 gatccaaatg gcagaccttt tctttcaatc ttgatttatc gatcgttctg atctgctcca
    14401 acaggataac ggagtctctt tctattcctg ttccagtagc tttgatccca atgtgagtcg
    14461 gaagcttagg tttagccatt tttgccgtta tggccgcaac aatgatcgtc gggctaaaat
    14521 ggttacctag attattttga ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca
    14581 cgactggaga aagatcagca aaataaatat ctcctctttt taccatagga tcctccttat
    14641 tcttgatatt ctcttggtat ccgctgtcct aatccgcaag ccacttcata gtggatcgta
    14701 cctaattgat ctgctatatc ctgcatagtg atttctttgt ctgcattttt gccgataagc
    14761 gtcacttttg ttccgacagg aaattcttga ggcaatcgga tcatcagttg atccatacat
    14821 acacgcccaa tcgtttcaca gtagttccct tctaccaata gagaaaaacc ctgcatcttt
    14881 cgtggccagc catctgcata accgatcggt atcgttccga tccactctgc ttcaggagtg
    14941 atatatgttt ctccatagcc gattccttca cctgctggga gttttttgac ttgaatcaat
    15001 tcagaaacca gctcaagtgc tggctgcaat ggataaactt ccggtagtgc gtgcccagag
    15061 ggattaagtc cgtacattgc tactccataa cgaatcatat tgccgattgt ttcatcatgc
    15121 cataaagccg ttgcactatt gctgacatgt acatatcgag gaagttcggg aagttttttc
    15181 agcacttcta taaagcgttc tttttgcaga ttccaatatg tatcatctgc ctgatctgct
    15241 gtagaaaaat gggtaaataa accttcccat tctaatacac gactttcttt gatgaatgca
    15301 gctgcctctt ttacttcttc aggtgtacaa aatccgatac gacccatccc agtgtctgct
    15361 tttagatgaa tcgaaagagg cgtctctagc ttacttttct ctaaaacagc agctgctgct
    15421 tgcaaccatt cccgtgtacc tgcagttact gataaatcat gagcaacagc tacagtcagt
    15481 gcgtcgtaag gaaccatatt caagataagg atgggctgag taaatccagc ttctctcaac
    15541 tcgactcctt catctaaatt tgaaacacaa aagcccgaag ctccacctgc aactgctgcc
    15601 tcagctgttt caatagctcc atgaccgtat ccgttcgctt ttactactgc aaacaattct
    15661 tttccttgcg gaagtcttgc aacttcattt gctacatttt cagttatagc ttttttatgt
    15721 atcactgctt tcgttgggcg gtgccaagcg acaaccatcg tttttccttc tttctagtct
    15781 tccaaaataa tttgtgcaaa agctgtttca tttgtatgag taatactgac ccatacattg
    15841 ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt cattttttaa aatctcgaca
    15901 tcttgaaagg taacttttcc gatcccagtt ccccaagctt tagagaaagc ctctttgcaa
    15961 gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag gcaaggactg gaatagtttc
    16021 atttcatcag aggtcaagat tcgtgcaatg aattttggtt tttcttcgat cagccgagtg
    16081 atcctaggaa gttcgactgc atcgatccca attcctttta tcatatgctt ttctcttttc
    16141 aataaattta gaacactctc attctaccaa attataacca ttttgccaca aataagtcca
    16201 caaataacaa aaatgaaagt ttctcttaaa aaagagaaac tttcatttta tgtttaatcg
    16261 ttatttgaac ggattacaaa tccgcgtttt ttatcattgt gacgtttacc gccatctttt
    16321 tggctgttat tatttttgct ataaccgcct tttgatttgt ttccacgata attaccgccg
    16381 tcacgacgat tacggttgtt tccgccacca cgtttgccat ttttattgta tccttttttc
    16441 tgcattggca atgggcgttc tggtgtgatc ttcactggca ctgcatcagc tggatctttt
    16501 gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag aatattcttc taataattta
    16561 tctgctgttt gcaggtattt atctagacca ttttctgcaa gttttgtttc gatttgttca
    16621 actgcagcac ctaattgacc tttgaatgct tctttttcgg ttggtggacg taaagtcgtc
    16681 atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg
    16741 aaagtcacag acataccgcc ttttccggca cggcctgtac gtccgatacg gtgaacgtag
    16801 ctttctggat cttgagggat atcatagttg tacacatgag tgacacctga aatatctaat
    16861 ccacgtgcag caacgtctgt cgctacaagg atatctaaat gaccgctctt aaatgaacgc
    16921 aatacgctca ttcgtttttg ttgagacaaa tcgccatgga ttccttctgc acggtaaccg
    16981 cgtgcttcta atccgcgtgc caattcgtct acacggcgtt ttgtacgtcc gaagacgatt
    17041 gttaattcag gtgtttgaac atcaaacaag cgagtcatga tatcgaattt ttcgtattct
    17101 tttgcgcgga catagtattg atcgatcaag tcagctgtca tttctttcgc tttgatcttc
    17161 acatgatgtg gatttttcat gaatttaacg ccaatattct tgatagctgg cggcatcgtt
    17221 gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg aaatgatttt ttcgatatct
    17281 tccaagaagc ccatattcaa catttcatct gcttcatcca aaactaatgt ttgaacggtt
    17341 ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac gtcctggtgt acccacaacg
    17401 atatgtggac gatctttcaa gccacggatc tgacggccaa tatctgctcc gccgtaaacg
    17461 gcttgtacac gtactttttt gtcgcgccct aaacgatata attcttcttg tgtttggata
    17521 gctaattcac gtgttggtgc gataactaaa ccttgtaatt cgtgacgatc tggatcgatt
    17581 ttttctaaca ttggtaatcc aaatgcagct gttttccctg tacctgtctg tgcttgtcca
    17641 ataacgtctt ttccagctaa tgctagtgga atcgtttctg cttggatagg cgttgcttct
    17701 tcaaaaccag cgcgttcgac tgatttcaac aattctggtg ataattctag ttctttaaat
    17761 ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt agcttttttg ctaccccgtc
    17821 gatttgttcg gtcaaagtgt attgtttctt tttgacagtg gccacgcacg tttttatcca
    17881 ttcttagccc ctgtggcacc accgaaaaat cactttgcga agtttaggca ttagaaaagc
    17941 caaacgggtc gcgttcagct ttatcattat tatgacatct ggcttcaaca agttgtttct
    18001 atggcaaaac cagtccaatt tctcttcatc tttcggcaat aggttattct aacatagttt
    18061 ttcgttttct gcaagtttac agatttttat ttcatttgct gaagttgttc taccacttca
    18121 aataagccca tgctgttgct gccttttagc ataatactat ctgttgcttc aagattttgt
    18181 ttgatagcat caatcaattt attcttttct ttttccaaat agaacacagg tagttggggg
    18241 tatttttggt tcaattcttc ttttagtgca tgcatttgtt ccccataaag gaaaatcatg
    18301 gcgaatttct caggatcgat atgttcactc atttgcgcat gcatatttaa agactctttc
    18361 cctaattcca gcatatctgc taacacagcg attctgcgtc cttttgttgg cagattttta
    18421 aaagtatcta ataccagtcc catggctgtt ggatttgcat tgtagacatc gctcaaaata
    18481 gctgcaccat ttcctgccgt tagccattcg gttctgtttt gagtgataga aacatgggcg
    18541 agcccttggc gtatctcagg tatggacagt ccaaagaagc gcccgatcgt atacgcaatc
    18601 aaagcattcg ttacattata acttccaggc agcgggatcg taaatgtttc tccttctact
    18661 acaaaatcgg tttgtgcttt tccttttgct gtcacttccg catgaacatc gccatttcca
    18721 ataccgaatg ttgtgactgt ttgtactaat gttgccgtta aaggtgtcag caacggttca
    18781 tctgcgggca caacgagtaa tccgtctgat acaagtccgt cagtgatttc cattttggct
    18841 ttagcgattc cttctcgcga cccaagattt tctatgtgtg cttcaccgat cattgtgatt
    18901 gctgcagctt ttggttgagc cataagtgaa agttccgtga tttcattggc gtgatccatg
    18961 cccatttcca aaacgatctt ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga
    19021 ccaatattat tgttgtaatt tccttgcgtc ttatatgttt tgtatttttc agacaagaca
    19081 gacgcggtta gatctttcgt ggtggtttta ccattgcttc ctgtaattgc aacgacttct
    19141 gcgcctactt tttccaagta ataggttgcc aattgctgca tggctttcaa aggatctgct
    19201 acaggaataa ctggaaaatt ttttggagct tgttcaacag gcaagctcca aaatgaagca
    19261 gatgctccgt ttgtgatcgc ttgctggata aattcatgtc catctcgcgt accagcaaga
    19321 ggaacgaata aacttccttc ggttatcttc cggctgtcaa attcgacatt ggtaatcttt
    19381 gtcagtgcag agcattcgct gcccacggct tgtgcaattt cttgtattgt tagattcatt
    19441 gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg
    19501 actctcactt ccaagtaaat ttctctattc gtatttagaa gctagaatga acgcggttac
    19561 gcaatcactc cagcctcttc tttatttctc tttattcatt tttttcaaaa aaagattgac
    19621 gctgatggta tcgattcatt cctaactgga tcagttcttc aatcaaatca ccgtatttca
    19681 agcccatatt ttcccataag agtgggtaca tactgaactc cgtaaatcct ggcatagagt
    19741 ttaattcatt caggaataat tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc
    19801 cgcttccacc taacatcgtg taagctaact tcgcgtactc ttgcgctttt tgataaactt
    19861 cttctggcac ttcggctgga atctgcattt cgattttatt attgatatat tttgcttcat
    19921 aatcatagaa tgctacgtct tttacgactt caccaggcaa agtcgtccga acgtcttcat
    19981 ttcctaatac agcaacttcg atttcgcgcg cttcaattcc ttgttcaacg attgctcgag
    20041 aatcatactg ataggctgtt gctaaagcat tttgcagctc ttctcggttt tctgcttttg
    20101 taatgccgac actagaaccc atattcgccg gtttgacaaa catcggataa agcaaagaac
    20161 cttcacattg atcaaatact tttttaggat tttctttcca ttgattctta agtactggta
    20221 cataaggaac ttgcggcaca ccagcagctt gtaaaatata cttggtcatg attttatcca
    20281 tggcacatgc actggtcaat acgcctgcgc cgacataagg catattcaat gtctctaaga
    20341 agccttggat cgttccatct tccccgtttg gcccatgtaa aactggaaaa acgatggctc
    20401 cttcttcttt gatttcgccc ggattgatca cttttcctgt aaagccttcc tctgtctgtc
    20461 cacttgggtc ccatgaaaga tgcaagacat ctttgctggc aggtttttct gttagtaatg
    20521 gacctttgac ccattgtcct tcttttgtaa taaatacgag ttgaacttgg taataattat
    20581 aataaatggc atttaaaact gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc
    20641 gtccgccata tagtaaagta atcttcaaaa gattgtcctc ctgtattcta aatcgttcag
    20701 tgatttactc tcatatttta gcacaaaaca aaaataaacg aataacttat ttataaaaaa
    20761 acgagccagc ttctaaaaga acgagcgtca tttatttttt gtcagctaga ttatttgtcc
    20821 cgttttttat aaaaagttat gataaagaaa aggagggatg atgatggcgc aaacaaatcc
    20881 acgcagccgc ttggcagaaa tcattcgagt gttcatcaat tacaatgtag tgccaaactt
    20941 tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt gaagaactag gccccacctt
    21001 catcaagata ggacagatgc tttctgttcg agaagatttg ctttcttctg ccttcactca
    21061 aacattcaaa acattacaag atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac
    21121 gatcgaaaca gaactttctc tttcattatc agatatattc gatgattttt caaaatcgcc
    21181 ttttgcctct gcttctatgg ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt
    21241 agtcgttaag atccaacacc ctaacatcgc cgaagagatc cgacttgatc ttcaactatt
    21301 tgaacgagcg atccctttga tcaaatacat tcctgaaact agcgtagttg atctaaaagg
    21361 ggtactccaa gaagtaaaac gttccttgat caatgaaatg gacttcttaa aagaaagtca
    21421 aaatggcgaa caattctatc aaaagaacaa tggctggaaa gagatccgca gccccaagat
    21481 ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt
    21541 gaatcattta atgaacgccg aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa
    21601 gcagctgaaa caagaagttg caaagctttt agttgagaac tttatgaaac aggtgtttga
    21661 tgatggtttt ttccatgctg atcctcatcc agggaatctg ctattccatg tactaacaaa
    21721 agaagaacag acacaagcta gccgaaaaac tgaaacagtc catgaaaaag agttcggttc
    21781 ctttgctttt cgagcctcca cttctgcaga agaccctgtt gcgccatata ccatcaacta
    21841 catcgatttt ggtatgatgg ggcatctttc tgcaggactt aggcaaaaac tcacacaagc
    21901 cgttttagcg ctgtatacga aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg
    21961 tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa gaactgacaa gttttcttga
    22021 acagtattat gattctccta ttgatgaaat caacttgcaa gaagtattca cacatgtcgt
    22081 gacgatttgt catcaaaata atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc
    22141 atttgggaca ttagaagggg tgatccgcgt cctcgatcct gaagtttccc tcatggaagt
    22201 cgcttcgcct tttgctcaac attattttct cactcatctg gatgtagaag atacattgaa
    22261 acaaagcgga ttagacttat tggaagggat gaaggctgcg cctaagatcc ctcaacagct
    22321 ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa
    22381 gcaagacaaa ttattgagca ggatcgaaag tatgatcaat cggcttgttt tcggtatgat
    22441 tttagctgca ttgatcgtag ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc
    22501 agaggtcgtt tccttattag ggatatttac gtatgctatt gccgcattcg tcattatttt
    22561 tttggcaatc gatgcattga tccaaatgta taagaagagg aaaaagtaga aaaaggttgt
    22621 gacagaaaga atcagcttca agaaataaga aggggtttta cataaattgt ttctcaaatt
    22681 tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct gaaacaccga gaataaaaaa
    22741 tgtgaaaaag ctgttctgca cccagtaata agaacaatca aaaagggaac atggaacaca
    22801 tttatcctgt ttccctgttc cctttttgat gtattcgagc ataaataaaa taccttcgtt
    22861 acctactatc ttctgtactt ggtaaacctt agtcaattgc cttttttaac gcttgacgaa
    22921 aagacatatg atctttctcc gtaaagggtt ttggaccctt tgtccttatg ccagcttttc
    22981 ttaactttcc actatgataa cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt
    23041 cttttccaga gtgatggaac actcgcacac ccttcggcaa tacaagtgaa gctaaaccat
    23101 aatcttgcgt gatcaaaaag tcattcttct taaccatacc gacgatttta taatccgcac
    23161 tatcagctcc gcggtctacg tagacgattt ggacatgatt agcgtattct ttggtcgtat
    23221 aatggtccac actggtcacg ataaccacgt caagaccata ggattctcct aattttatga
    23281 catcttcttt tactggagaa ccatctccat caatgaatag cctcattctt tttcgccttc
    23341 ttccataaat gataaacagt tactaatccg ctcagtaaaa gaccaacatt gatccatttt
    23401 gccaagataa gcagttgtac actttctatc ggcactgatt catggttcag cgtgatcaat
    23461 aatagatgga ttggctctcc catttctttt gctaaaacaa acaaaagcgt catcaataaa
    23521 aactggtgga tcacactccc tttattttga gtagtatact tgacaacgat ccggcgatcc
    23581 attggaatag ctgtatcagt ttgataatat tccttattta gccagctgcc tgttactacg
    23641 tgccagaaac taagcagaaa gacacctatc gcaaaaccat ttggaatcaa gaggaccaat
    23701 aaagaagaac tcagtccaag caattgcata gccaatggag accatgttaa acgtttcaaa
    23761 atccatggtc cgactatttt tgctgcaatc aagcctgctg cataaggcaa atacataaaa
    23821 atcgaaagtt tttctaatcc gtacagtatg ccaacataaa aactgctaaa taaaaaaagg
    23881 aaattcccta gcattccatt tagaaaagta aacagattta gccagcttgg caacttccat
    23941 tccttcttct ggtgtcctaa aacaaacacg aacaagatga acagcagcaa gaaaccataa
    24001 atagcaagat caaaaagcct ttcatcgaat aacaatcggg catttctcaa aagaaacaat
    24061 aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag ctaccagatt tcttttgatg
    24121 tctttgaaat ccagttcgta acgcggataa tgactaaccg tatggtaggc catgacgtaa
    24181 aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct
    24241 tgatacagga gaaatagcca gatagctgca aataagtact ttttcccatc catattgata
    24301 aaaccttgcg tcttttcgtg aaaattgacc gtggtattag caggtacaag ccatgctgca
    24361 ctcagcccta gcaaaacact tgaaaaataa aataaaggaa aataaaatac gcctaatatt
    24421 ccaagcaatg aaccagcacc accaatcagc agagcgatca tcagcaacgt gtaactatct
    24481 agaccaaatc gtagactgtt gactaaaaat agtccagtca tccgaaaggc ataaaacagc
    24541 gtaaatggca aaatcgtcag ccaattatgc gagtctgtta gtcccaaaaa taaaagataa
    24601 ggaataaaaa taaccgtgtt acttaagata aagggcgttg tttgtgtaaa attacgccca
    24661 aatcgtttga gtttttcgaa catgacaatg gctccttaaa cagtcttata actaatctgc
    24721 tcttcgattt tagcattaaa ggggaaataa accaatttta cagaatatat tcttgtaaaa
    24781 aaaaatacag aaagaagcat aagcttcttt ctgcattttt acggtacttg attactcaag
    24841 cagacaagcc cttctccaca aaagtcttgc ccgacacccc tgcatccggc aggtgataaa
    24901 gatagaaatc aattatcctg tgcctccaaa atcaattagg agctctgtaa accagagtcc
    24961 ttctcgaccc gtcgcataaa tttactttaa cacagttcct atgtttatgc gagagctttt
    25021 ttcattttat aatcgaccat ttgaaatcct tgaccgatat ctgaaataag ttcttctgta
    25081 atctcaaatc cttcatgctt ataaacctcg attgcttgat gattcccctg attcactcgc
    25141 aaaaagatct ctctttcctt tgtttgcgca gcaagttctt cataccagcg aaaaactgaa
    25201 gaagtcaatc cttgaccacg tactttattt agcaaatata atttacttaa ataaattttt
    25261 ccatttatct cttcataagc agtgtaaccg acagtctttt cttcgctttt taataaaaag
    25321 taggacacac cttctgtcag ttctttttga atctgttttt ttgactgata agttttcagc
    25381 atgtaatcca cttgtttttg accaatgatc ggcacaaaag cttccggcca tacttcttgt
    25441 atgactgcca tcagctcatc cagttcattt tctgttactt ttattttttc catacaccca
    25501 cgtccttttt tacattataa atgaccttgc gcttgatgga ataaaaagag catgatcatg
    25561 ctatacacac ccaccgacca tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa
    25621 gataatttcg tcaaaccagc tactagacag atcaagtcgt ctggcgcaaa gggaagcagc
    25681 aaggtaacaa ctagtacttt tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat
    25741 ttctgatact tttttggcga taaaataagc tggacaaagg ctacgccata gtaacggaca
    25801 agcaaaaatc cgattgcttc cccaatcact aggccaatac aactatataa aagcccaaat
    25861 ccattgccaa acatcagcat gcccgctact gaggagatcc ctcccggcaa aataggaatg
    25921 atcacttgga tcacttgcaa cagaacaaat atcatcactg catacttgcc aaattgctgg
    25981 ataaacgctt gcaaagacgt gctcgatcga aaaatcccat gatgataagc ataaagaatc
    26041 aacacaaaga aaaaaaacag accaataatg ggcatgatct gaagacattt ttgtaaaact
    26101 gatccttttt tagacatcta tattccccac atcttttttc atttattaaa actgcctcct
//
LOCUS       DAIGWC010000038        24258 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.038, whole genome shotgun sequence.
ACCESSION   DAIGWC010000038 DAIGWC010000000
VERSION     DAIGWC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.038"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(45..1340)
                     /gene="purB"
                     /locus_tag="NOB74_001592"
     CDS             complement(45..1340)
                     /gene="purB"
                     /locus_tag="NOB74_001592"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HCI1220785.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1353..2477)
                     /gene="purK"
                     /locus_tag="NOB74_001593"
     CDS             complement(1353..2477)
                     /gene="purK"
                     /locus_tag="NOB74_001593"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HCI1220786.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2470..2958)
                     /gene="purE"
                     /locus_tag="NOB74_001594"
     CDS             complement(2470..2958)
                     /gene="purE"
                     /locus_tag="NOB74_001594"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HCI1220787.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3374..4681)
                     /locus_tag="NOB74_001595"
     CDS             complement(3374..4681)
                     /locus_tag="NOB74_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HCI1220788.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4684..5265)
                     /locus_tag="NOB74_001596"
     CDS             complement(4684..5265)
                     /locus_tag="NOB74_001596"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCI1220789.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5381..5478)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5837..7129)
                     /locus_tag="NOB74_001597"
     CDS             complement(5837..7129)
                     /locus_tag="NOB74_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1220790.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7126..7749)
                     /locus_tag="NOB74_001598"
     CDS             complement(7126..7749)
                     /locus_tag="NOB74_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220791.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7752..8588)
                     /locus_tag="NOB74_001599"
     CDS             complement(7752..8588)
                     /locus_tag="NOB74_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1220792.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8605..9492)
                     /locus_tag="NOB74_001600"
     CDS             complement(8605..9492)
                     /locus_tag="NOB74_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1220793.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9508..10791)
                     /locus_tag="NOB74_001601"
     CDS             complement(9508..10791)
                     /locus_tag="NOB74_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1220794.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11474..12157)
                     /locus_tag="NOB74_001602"
     CDS             complement(11474..12157)
                     /locus_tag="NOB74_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCI1220795.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12175..12792)
                     /locus_tag="NOB74_001603"
     CDS             complement(12175..12792)
                     /locus_tag="NOB74_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI1220796.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12802..13626)
                     /locus_tag="NOB74_001604"
     CDS             complement(12802..13626)
                     /locus_tag="NOB74_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCI1220797.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13619..14179)
                     /locus_tag="NOB74_001605"
     CDS             complement(13619..14179)
                     /locus_tag="NOB74_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220798.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14353..15309
                     /locus_tag="NOB74_001606"
     CDS             14353..15309
                     /locus_tag="NOB74_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1220799.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15614..16570)
                     /locus_tag="NOB74_001607"
     CDS             complement(15614..16570)
                     /locus_tag="NOB74_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HCI1220800.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16674..17276
                     /locus_tag="NOB74_001608"
     CDS             16674..17276
                     /locus_tag="NOB74_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI1220801.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17364..18863)
                     /locus_tag="NOB74_001609"
     CDS             complement(17364..18863)
                     /locus_tag="NOB74_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HCI1220802.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18879..19403)
                     /locus_tag="NOB74_001610"
     CDS             complement(18879..19403)
                     /locus_tag="NOB74_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HCI1220803.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19701..20450
                     /locus_tag="NOB74_001611"
     CDS             19701..20450
                     /locus_tag="NOB74_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCI1220804.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20441..21226
                     /locus_tag="NOB74_001612"
     CDS             20441..21226
                     /locus_tag="NOB74_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HCI1220805.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21195..21911
                     /locus_tag="NOB74_001613"
     CDS             21195..21911
                     /locus_tag="NOB74_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI1220806.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22013..23047)
                     /locus_tag="NOB74_001614"
     CDS             complement(22013..23047)
                     /locus_tag="NOB74_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HCI1220807.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23051..24109)
                     /locus_tag="NOB74_001615"
     CDS             complement(23051..24109)
                     /locus_tag="NOB74_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HCI1220808.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7188 a         5222 c         4225 g         7623 t
ORIGIN      
        1 tttttgctat tctattttaa ttgaattttg caactcactc ttctttattc caaacctact
       61 cgtttgaata tcacgtcaac gtttttcaaa tgatgatgat aatcaaaggc atcgtctatt
      121 tcttctttag ataataccga tgtgatggtt ggatcttctt ctaacagcgg gcggaactgc
      181 acttggttgt cccaagcgta cgcagttttt ggctgaacaa gatcataagc ttcttctctt
      241 gtcattccct tatcgatcaa tttcagcata acgcgctggc tataaatcaa accaaatgtt
      301 gcagacatat tccgcttcat gttttcagga aagaccgtta gatttttaac gatattgcca
      361 aaacgattta acatgtaatt caataaaatc gtggtatcag gcaagatgat tcgttctgct
      421 gaagaatgag aaatatctct ttcatgccat aatgtgacat tttcataggc agtgaccatg
      481 tgtccgcgca ccactctggc tagaccagcc atattttctg aaccgatcgg attccttttg
      541 tgcggcatag cagaagaacc tttttgacct ttcgcaaaaa attcttctac ttcacgtgtt
      601 tcggattttt gcaatccgcg tatctctgtt gcaaaacgtt caatacttgt agcaataagc
      661 gccatcgctg agaaatattc agcatgtaga tcccgaggga gaacttgagt agagatttct
      721 tgtggacgga tccccaattg tttacataca tactcttcaa taaatggcgg gatatttgcg
      781 aacgttccca ctgctcctga gatttttcct gcttctactc cttttgccgc atgttcaaat
      841 cgttcgatgt tccgtttcat ttctgaatac catgtggcaa gtttcaatcc aaaagtagtt
      901 ggttcagcat ggacaccgtg tgtccgaccc atcatcactg tatatttgtg ttcttttgct
      961 ttttcgccaa tgatttccgt aaaacgtttc aagtcttccc gtaaaatatc atttgcttgc
     1021 ttgatgagat agccataagc agtatctacg acatccgtac ttgttagacc ataatggacc
     1081 cattttcttt cttctcccaa tgtttcagaa accgctcgtg taaacgcaac gacatcatgg
     1141 cgtgttaatt tttcgatttc caagatccga tcgatatcaa atgatgcatg ctcacgaatt
     1201 tttttcacat cttcttgcgg gatttcacca agttctgccc aagcttcatc tgctaaaatc
     1261 tcgacttcga gccacgcacg gtatttgttc tcttccgtcc agatattccc catttcaggg
     1321 cgtgtataac gttctaacat gttttttctc ctctaatccc aaatattcgt ttgtttgatt
     1381 tcttccagcg tttgctggat gtcttctgtc aagatagtga tatgtcccat cttgcgacct
     1441 ttttttgctt gtttttttcc atagaaatgg aattgccagt ctggcttatt ctcaatcaag
     1501 cgatagcttt ccagcagttg ttctcccaaa acattgacca ttactgcatt gcttatcaaa
     1561 cgtacttttt ctcctaatgg ccaaccacaa atacctcgaa tatgggcatc gaactgactc
     1621 atagaacaag cttcaataga ataatgtcca gaattgtgag gacgaggagc taattcattc
     1681 acatatagcc cgcctgtttt tgttaaaaac atttctaccc ctaaaacacc tgaaaggctc
     1741 actgcttctg caatcacacg ggcaatacgc tcagcctcct cgatcacatc ctgatcaatc
     1801 gcggctggag caatcgtttc atgaagaata ttgttgtggt ggatgttttc cacgaccgga
     1861 aaagtcgtga aatctccttg accatttcct gccaccatga tcgaaatctc tttttcaaac
     1921 gggatccatg cttctaaaac acaggttcct tctcttaaaa ggtccatggc aggagctaga
     1981 tccgcccgac ttttcaaaac atactgcccc ttgccatcat agccgcctcg agtggttttc
     2041 aaaacacaag gatagccgat cccgtcaatc gcatcttgga tatccgtcgg actgacgatc
     2101 gttgcataag gagcaatcac gatgttattc gtttccaaaa aagatttttc taacaggcgg
     2161 tcttgcgtaa tcgcaagcaa gtctgtccct tgaggaataa atgacatggg taaaatcgca
     2221 tttaacgcct ctacactgac gttttcgaat tcataggtaa tgacatctgt tcttctggca
     2281 agctctttca gcgcaaaggt gtcatcatag acactttcaa tgtgccaatc tgcaacttgt
     2341 gcggctggac aatcgctcac aggatccagc acacctactt taaagcccat ttcttttgca
     2401 ctaatcgcca tcatacgacc taattgaccg ccaccgacga tcccgatcgt tgaaccaggc
     2461 aacaaaggtt taaccaagtt gatcactact ttctataaca gttttagcca acattgaacg
     2521 tctttcagcc aatttagcct ccaattctaa atcatacatg gaaagcatct gtatcgcaag
     2581 tagtccagca ttaattgctc ccgcttttcc gattgctgta gtagctacag gtactcctcc
     2641 aggcatttgg acaatcgaaa gaagcgaatc caaaccattt aatgttcgtg attggaccgg
     2701 tacaccgata accggcaaag ttgtttttga tgcgaccata cccggcagat gcgcggctcc
     2761 ccctgctcct gcaataatga ttttgattcc tttttttcga gcgttttgtg catattcaaa
     2821 catcaaatct ggggttcgat gagcagaaac gacctttttt tcataagaca caccgaattc
     2881 atccaatatt tgacatgctt ctttcattgt ttcccaatct gaagtactcc ccataatcac
     2941 agagattttt gctgtcattg tttttcctcc cagtttttct acattcatat tttaacaatc
     3001 actttttttg atgtcaaaga aatttcgaat gttaacaaag aaaaacattt tattgttcgt
     3061 gtttattaaa gataaaaaaa aggaatgtga caaaagttag gtcacattcc tttttatgga
     3121 taaacggtgt tctcctgcca actcctcggt cacaaggaac aatattcaac aaacatgaga
     3181 agcttttttt tgaaattgtt ccttgtgact cggagatgaa cggcaggctc acgacctctt
     3241 ccttcaacgg tgttcaatca gctgaccctc ggtattagct caaacaaacg gcaaaatacg
     3301 aggaactatt tttccgtttg tttctctaac aatcaggtca aaacgctgat ttcacaacct
     3361 ttcttttgct ctattacttc ttgaaggctt cttccaatat ttcttcatct tttttcaatc
     3421 cattaaagat caaattcaat atgatagccg taatgctact cattacgatg ccatttccag
     3481 tgaacatttg caatgtttgc ggcatttgac tgaataatgt cggcgtaaca ttgaaaccca
     3541 gcccaaatcc aacagaaaca gcaacaatca atagattttt atcattgctg aaatcaactt
     3601 ccaacagcat acggattcct tggactgcca ccatcccgaa catgactaac attcctccac
     3661 caagtaccgg ctcagggatg atttgtgcta acgcaccgat tttagggaat aatcctaaaa
     3721 caatcaagaa gaatgcagag aaatagatgg gttttcttgt tttgattccc gaaagttgaa
     3781 ccaatccgac attttgagaa aagccagtat aagggaatgt attgaaaata ccgcctaaga
     3841 taacggcaag tccttctgca cgatatccct ttttcaattc ttcttctcca acatttttcc
     3901 cagtaatgtc accaagtgca aaatatacac ctgttgattc taccatgctg accatggaaa
     3961 tgatgatcat tagtaaaatc gaccatacgt cgaaagttgg tttaccaaaa taaaagggtt
     4021 gtggaacatg gaacaacggc gcatctccaa tcgcgctcag atcaatcatt cccatgaaag
     4081 cagctaagat gcttcctccg actaaaccaa tcaataccgc gattgaacga atgaaccctt
     4141 ttgccagcat ttgcacgcct acaattagga gaatcgtcac aaatgcaagt agcagatttg
     4201 ttttgtcacc aaaatcagct gctgttgcat tacctccacc cattttctcg attgctacag
     4261 gaatcaaagt caaaccaata acggtgataa ccgttcctgt tactatagga gggaatagtt
     4321 ttttaatttt agaaaagaca ccagaaacta acacaacaaa gatcccagaa gcgataatag
     4381 atccgtagat agctcctact ccttcattgg ttccgatcaa gatcagtgga gctactgctt
     4441 ggatcgcaca tcctaaaacg acaggcaagc caattccgaa aaatcggtta actgtcaatt
     4501 gcaataatgt cgctaatcca cacataaaga tatcaattga aatcaaataa gtcatctgtt
     4561 cttgattaaa gcctagtcct gtaccgatca aaagaggcac cgctactgct cctgcataca
     4621 tcgctagcag atgctgcagc cctaaaaccg cagcttttcc attttgtgtt tctttttcca
     4681 cgattatgcg tcctcctcaa gaaactcaac ttgtccattc gtcaaggaag caatacgcgc
     4741 aagagaaacg actctcaatc ccatttcttc aagtaactga cgtccatctt ggaaagactt
     4801 ttcgatgacg atcccgattc cttctacttg cgctccagct tgctggcata attcgatcaa
     4861 tccttttgcc gcttgtccgt ttgccaagaa atcgtcgata atcaatactt tgtcttctga
     4921 agataaaaat ttacgagaaa tagaaatcgt acttgtcact tgtttcgtaa aagaataaac
     4981 agaagctgtc aataattctt catccatcgt caaacttttt gcttttctag cgaagatcat
     5041 tggaacatct aattctcttg cagcaaataa agctggtgcg atcccagaag cttcaatggt
     5101 cacaactttc gtgattcctt gttctttaaa tacttctgca aaccgttttc ccatttgttc
     5161 catcaataca gggtctactt ggtgagtgac gaagctgtcg acttttaata cgccctcgcc
     5221 taatatacgt ccgtcttttt gaatacgttc aactaattct ttcactttat ttgctccttt
     5281 atcatttatt aataccgaaa taaccgcttt tgtgcaaaaa cctactatgt ttctgttaaa
     5341 gaaaaacacc ctccacttta tcataagaaa agaagggtga aatagccaat cttttactta
     5401 tagtccagca tttacggtac tggctagaaa ctgtcatcca tattatgacg atatataagt
     5461 aggtatgtaa aactaataat agtgtaaatt cattttcttg caactgtttt gcacgtgaag
     5521 gcagtttgcc atatttgaat aaaaaatgtt gtttcaaata ttgaaaacag tctaacacta
     5581 ctttctgaaa ctgacaacgt ggtttactta tttttttgta aaatctaatg atttttaatg
     5641 cattattcct ttttgttcgg gtttaaatag ttatttttat tttctcctat ctaaaaaagc
     5701 agcccacata aaaagaaggc atgacaaaaa gcatgtcata gccccttttt ccgaataaat
     5761 agtgttcaaa agacagccta tcggcaataa ggcaagattt tataaactac gggaagtaat
     5821 ttccgtaaat ctattcttat tcttttaagc tgacaagctc gtcaatcact actgcttttc
     5881 ctgaagcaat agaatgattt gctgcgattc ctgtcaaaat cgacaaaata ccatctacgt
     5941 gagttgctgc ccgattccac ggatcttctt ctttttcttc accaaataga tcatctaata
     6001 aacgcggatc tcctccgcca tgtccgcccg cttcttgttc gacgattacc tcatatggct
     6061 caccgaacat cggatagaca tggatggact gaagaacggc tgctccttca tcctttttat
     6121 ctccacctgc attgatgtaa gacttttcga tcactttcat ttcgatccgt cctttgctgc
     6181 cattgaaaga aacattgaat ccttcccacg gcatatacgc gtttagcgaa tacgtcaaaa
     6241 tcgcaccagt ttcatatttg accgttacgc ctagtgtatc ttcaatagag atatcatcgg
     6301 aaaatacact gcggtcacga atatatccac tgtctttttc tgcttctaaa tacatttctc
     6361 gcaattcctc attggctgac aggtctatag caaatggatc agctttagct agttcgcttc
     6421 catagcatcg actgtaaaat atttctactc cgcgtttctc cgcattatgc atcccataaa
     6481 agtttaatcc accgaatgca aatacctttt ggggacggct gttcaaccaa aaattcacta
     6541 gatcaaaatg atgggtagat ttatgaacaa gaagcccgcc gctattgtgc ttatttcgat
     6601 gccatcttct gaaataatct gccccgtgtt gcgtatttaa cagccattcg aagtggatag
     6661 aaaacacatc accaatcaca tcactttcta tcagttcctt tatcttcgtg tgatacggtg
     6721 cataacgata attaaaagtg actcgcaggc ttcttcccgt ctgtttttgg accgttatta
     6781 tttcttgagc tttttcctca tcgatagtca gaggtttttc gcaaataaca tcatatcctt
     6841 ttttcattgc acgaatgata taatcatgat gcgttcgatc tactgacgta ataatgactt
     6901 cagccggccg tacgtcatcc agtagttgct caaattgtga tggcatacat gtctttactt
     6961 ttttctgtcc atacttgttc acaagtatcc gatttgcata atccatcctt gtttgagata
     7021 catcacaaaa accgactagt tcacaagttt gatgatacgt agaggcaatt gcctcataaa
     7081 aaaaacgcgc tctcccacca agtccgactt gtacatattt tttcttcatt taaagtcatt
     7141 ctccttttct tttaagcaaa atactgtgac aaatggcagc cctggataca gtaatgcagt
     7201 gagtaaaaaa tcatgctgta tacaccagaa cagtccatac aaaaggcata aataccacag
     7261 aaaccccttg acgttttttg acaacagcca gatattcctt ttgatcaaat aaacaagact
     7321 atctgcttta tcttctttgc agatatcaat tagcgtacta aaaaaactat gggatacaaa
     7381 aagcaacaga cacaatagaa aaggaatcag ataccaagct ccaatctttc ccactaataa
     7441 ataccaatca actgcaaaaa taatgacaaa cagctgaaac aacgtaatga tgaaacacat
     7501 ccgtttgatt tttcctttcc tccaacatac ctttttttct gccaagtaat ggacagatag
     7561 ataataagaa ggatacatca tcaaaaaata aatcagatag acaacacgag cagacagcac
     7621 taatcctaaa gtgaacaaac atcctagaac taaagcgaaa agagcattac tgataagact
     7681 ggttaaaaaa atccgacaga catagtagtt gagcttgtaa agaaacatct cttctattgg
     7741 ctttttcata ttcagccctt cagaccgctt gtactgatcc cctggacaag atatttattg
     7801 aagaataaga aaatcagaaa aaccggtagc agcgacaacg tagacatcgc aaacatactc
     7861 gcgtaagtcg tactagatcc agcgtctgca aataatttga tggcaatcga taccgtgtaa
     7921 gatctcggct tgtttaaata aatcaatggt cccatgaagt cgtcccattt ccaataaaac
     7981 tggatgatga tcgtcgtgat gatcgaaggt ttcagcaaag gaaaaataat tttggtaaag
     8041 acactatact tgctgcatcc gtcaataatc gctgattcat ctaactcttt ggggatgctg
     8101 accatgaatt gcatgatctg gtaaatgaaa aatgcttgtc caaaaaaatg tggtaaaatc
     8161 agcggcacat acgtcccaac caaattcagc cgattgtaaa taataaactg cggaatcaaa
     8221 atcacttgtg caggaatcat catcgttact aacatgacga cgaaccagaa tctttttcct
     8281 ttgaaatcga ttctcgataa tgcgtaagca atacaagtcg agctcagaac tgtccctatc
     8341 gtcgaaactg cagagatgac aaacgaattc ctaaagaaag taaaaaatga aattccagca
     8401 aaccccgccc atccttttgc gtaattttcc cattgaaaag tctctggaat caaattcagc
     8461 gaaccactca taatctcttg atccgtttta aaagaacctg cgatcatcca taagaccgga
     8521 taaatcatga ctagacctaa tagcaaaata aaaccgtatt gaaaccattt cgttactgta
     8581 ttattcattt cttcctcctc tcattcacac aacgacccat ttttttgatg atttgaaaat
     8641 cagaaaggtg acagctccca taatcaacag catgatccac gaaatagcac tagcataccc
     8701 catagaatta aaagaaaaag cttggttata cacataaaga gcataaaagt tcgtggcatc
     8761 attcggacca ccttgggtaa tgataaatgc ctgcgtaaaa gtcataaacg ccgcgattgt
     8821 ctgcataacc aagttataca aaatgatcgg cgaaagaaga ggtaacgtga tcttgtaaaa
     8881 cgtctgccat ttgttcgctc catcgatctc tgccgcttca taatacgagc ctgggatctc
     8941 tttgatacct gcagcaaaga tgatcattgc cgaaccgaat tgccaagcag acatcaaaac
     9001 aagagggatc atgaccagtt tttgatcgct aaaccaggaa agcgcaggtg cgcctaatcg
     9061 ttccaggaaa atattcacta acccgttttt agaaaacaac tcccgccaaa ctagagcgat
     9121 agaaatactg ccaccgatca aactaggcac ataatacaaa gaacgaaaga aagtcgttcc
     9181 tttgatattc ctcgttaaaa gataagcaat caatagacca aagatcagtt tcacaggtac
     9241 agatgcaaat acatagagaa aagtgactcg gatggagttc aaaaaacggg catcactcag
     9301 catctttata taattatcca agccgatcca tgagactgga tttcccaaac gataatcggt
     9361 gaacgaataa taaagtgaca agatcatcgg tatcactgtt atcaatagaa atcctaggat
     9421 gaatggagaa gcaaatacgt aaccgaccac attgtcttga tccaagaacc gttttagttt
     9481 ttcttttttc atgccttcct cctgctgcta tcctagaatg tttgacgcaa actcataaag
     9541 actctctgct gcttcttctg ctgttacttc ttcataaatg actttttcaa ctaaaagatt
     9601 gtattggtct tgaatttccg gattcaaagc actatcaaag acattcactt cgccgttgtc
     9661 catatcggaa atcatttcta aataatcaaa tgtcgcttgc aaagttgcat catctgcacg
     9721 agcgagctgt tctcgaatat tcgacatgat tggtacacca cgttctcctt ttaaaatttc
     9781 attggcttct tcactgtttt gaaagaaatc aataaactta gcagcttctt ctttatgggc
     9841 tgagcttttt gccatactca gcatttgcga agaacgtaaa gggataccag attctccatc
     9901 tgcttttctg cgaggtggat taatcaactg aatctccata tcttcaggag cccctgacaa
     9961 tatttctgtc aactggttac ttgatagaaa caccattgcc gcttctctat ccctaaccgc
    10021 ctgaaaagac agatccgtcg tacttgcagc tccaccacct ggttctggat gggccccttt
    10081 gtctaccaga tttttacgca gctggaaaaa atctgttaga tagtctggat tttcaaatcc
    10141 caagctgtta gatagatctt cccgattata aaaattcaat cctttctcaa cttgtggtat
    10201 ttgaataata cagccagcta taaaatcttc gaatcttgaa atagcataga ttcctaattc
    10261 ttcagtgatt tgatagctga tttgttcaaa ttcatcccat gtccaatttg aagctggttc
    10321 agggatattt aattgttcaa atatattttt attgtaagca atcgcaaacg aattcacccc
    10381 gttagacagt ccaactaatt gcccgtcgta agtcgtcgtt gctaaatagg attcatctgc
    10441 attagaaata tcaattatcc cttgctccac atattcatct aatggttcaa tctgattgat
    10501 gtattgagga aattgattgt tcagttggaa aatgtcccag atatcatctg atgctgctag
    10561 tgtacctaat tttgtgtaat atccttcata atcataaaat tcataatcga tcgtcacatg
    10621 gggatttttt tcttcataaa gctcgattac ttttactgtt gcatcgtgtc ggacttgcga
    10681 accccaccaa gccatgttca gcgtgatttt tttgtcatct tcttgcccac aagccgtcaa
    10741 gaagaataac ataacactta aagctaagat gattctcatt cttttcttca ttctctgcac
    10801 ctctacttcc attgttattt ttcaatatac tgtattttta tacagaacat atttattaaa
    10861 cgatcttttt caaggggaat aaaaaccaag acttgcctta tcgttctgcc taggatgaac
    10921 aactcaatac tttcaagaaa aattagatag tgctgattct tctttcatcg ctaaaaacac
    10981 ttcttgcttc aatgatggga ggataattac gcaaagaaaa aaggatatca gacaactgcc
    11041 caatatcctt gacatagcta aataagcatg cttcttcgtg tgcgctcttc cctaaaaaac
    11101 agaaaaataa ctagtaattc tgtatgaaat taggtacaat atacacgtcg atgcacaagc
    11161 attgactatg gcaacttgat tggtcagttc ccgctgactt ttcaagcccc gacaatttag
    11221 ctgctactaa attgtcgggt gcctttttta gtttttattc gtttttcatt ctatagaaag
    11281 cgcttcaata aatcaagaca tttttttgtt agaatgctaa taataacaaa aggttttaac
    11341 tcttcttatg tacattacag gtaaaaaaac aaaaaaattt ctcttttttt tgaattctga
    11401 acaaatagta ctggagtaca aaagacgagg aagagccact atctgctctt cctcgtcttt
    11461 tgattctcac ctgttattca tgattctttt tctcagtttc ccgatatttt tccattttac
    11521 gactaaaaag ctctccgcta cttggtggcg tatatgtgat ggcatttgct cctgcttgaa
    11581 tggtctcagc aatactttct tccgttggac cacctgtcgc aatgatagga agttcaggat
    11641 attttttacg aaaatggcgt actgcttctg cagtttcttt acctgcactg atattgataa
    11701 tcgaaatacc agctgctaac ttttcatcta tttctgtata tttcgacgtt accgtactga
    11761 taactggaat atcaactact cgacaaactt cttttactgt ctctaaaggc gtaggaccgt
    11821 tcaaaacgac ccctaacgaa ccttgcgctt ctgcgaacat gctcatgtag gaagaacgag
    11881 caccttgtgt caaaccacca cctacaccgg agaaaactgg aatgtcagct gcctcaataa
    11941 tgcttttagt aatcgctgga tgaggtgtaa aaggatacac agcaattact gcattcgcat
    12001 ttgtattacg tatgatcgca atatccgtag taaagatgat cgaacggatc aattttccaa
    12061 atatcttgat cccgcttgct tctaaaatga tttccggtac tcttacgata tcttttctca
    12121 attccgtcat gatttctggc gtaaattgtt ctgccatcag ccacttctcc tttgctatct
    12181 ccggtcatac tgattcaatt gatacgtctc gatgacctgg atgatttttt gcgcataacc
    12241 ggggtctgtc gcataacctg catcttgcaa tgcttgtgcg gcttcctgat agttggtggc
    12301 cgtaatcact ttttcataca gcgcaggatt ccaatctact ccttggacga acagttgtgt
    12361 atggtcatcc atggactgtt cccatgaatc atacactttg aagtctcctt ggatagttat
    12421 ccattcttcg ttaacaaatt cctttgtttc caggcttact ttcttctgat ccccataagc
    12481 cttgatcccg aaaagattat tgtatttgct agccaaggta ctttttcccc aatttgattc
    12541 taatatagct tgtcctaaaa tgatactagg aagcactcca taaccatctt gtagttcttg
    12601 ggcatgcgga acaagccgtt caataaattg ctgatgggat tgcgcttcat tttcttgctg
    12661 attatcagta aaaggagaag acagattctt caaggaaaaa acaaaggcta agagtatcac
    12721 tgctacaccg gcaaccactg ctggccaacg gatattcttg cgcttttgct ttttccactt
    12781 ttttttcgcc atgatcaatt cctacttttc atttaattca ttcagatatt cttctagcgt
    12841 caattggtgt ttggtgatat actcagcgtt ttctttaccg acataacgta agtgccaagg
    12901 ttcatatgtg atcttagtta tatcttcgtg tccttttgga taacgaacga taaatccata
    12961 ctgcgcagca ttatctgcga tccatttagc tccaggctga tctccgtaac ttgcatccaa
    13021 tacagtagaa ggataactgt tgtaccagtt ttgatcgacg acatcgactg ccagacctgt
    13081 gtggtgttcg ctgtatcctg gctccgtaat cgtttcttta gtaatctttg tcgcctcctc
    13141 ttctgataca ccttgacgac tcatcacatc ttggacattt tgttcgaaaa cttgttgttg
    13201 ggatgataca gaccggtaag ctgagaccat cactaatgga aatccagctg cttcagcagc
    13261 cttggcaaat gcttcatatt ctggagcaat gcgtttgtcg atcaagtatc cgttacttaa
    13321 tgatgccaat tgagtagact catcaatttc tttttctaat ttgtgatctg gaccaaccaa
    13381 aactagcttc caatcgtctg ttttaacatc tggcaattgt ttggacgtac gatcttttgt
    13441 ttctttgtcc tttaccttgc tgctggttgt ttgactgttc ttttctttac tagcagttgt
    13501 tttggtgctt gttcgttcga ctgcttgatt gccggcttga acatgcgaat catcatcgct
    13561 aaaaataaca tagcccattg ctgcgatcat aatcacaact gctccaaatc ctaaaaattt
    13621 attcacttga aaaatccttt cgttgttctt cacgttcccc attcgcctca tgaacgtaag
    13681 tttcttccag attttcattc acccaatcga gaagttcgat tttttctcct tcgatctgtt
    13741 tttgaacatc tgctggcaga cgaaaattca aaatatcatc atagccccat tcatcatatt
    13801 gaatacttac tttcaagtca aggtatctac cagcctgctg attatttttc aaagggatca
    13861 gctcgacttt tgctgctttg ctgctaagcc atttttgcgc gatgcgtgtt ttgatttgct
    13921 tgtactctgc aacggcaacg tttcgttttt cgggaaaaat aatcgtttga cgcaaaatct
    13981 tttgcgttag catccattca taatcagtga aaagattttt tactttctgc atcgcttcag
    14041 atggcagatt tttctcgcca tctttccatt tttgccattg ttctggactg atcagcaagt
    14101 attcatctaa aaaatttttt tcagtttcaa actgttctaa taatacactc ataataagat
    14161 caatatatac ttgatgcacg tttatcccct ccttttaact attctactta agttttgatc
    14221 aaaaagcacc tcttaaatcg ctgctttcat tttttttaat gtttcaagtc ctctcctctt
    14281 tattcttcgt gatttttgtt ataataatag acagacaaga aactcaatcc aactatgaag
    14341 gagcgttttc agatgaaaaa atatcaatgg ggaatcgttg gtcttggtac catcgcacat
    14401 gagtttgccg aaagcttcaa tcaagagacg agcgaactaa cagcagttgc ttccagaact
    14461 tcagaaaaag cggaaaactt cgctcaccgt tacaatattc caaaagctta cggaagctat
    14521 caagaaatgt tagacgatgc tgaaatcgac atcgtgtaca ttgctgtacc aaatagacag
    14581 catatcgacc atatcttggc agcattggaa gcaggcaaac acgttctatg tgaaaaagcc
    14641 atcacgatga ataaaaaaga actggctgac gctatgcgct tagcagaaga aaagaatttg
    14701 atcttagcag aagcgatgac aatcttcaac atgccacttt atcagcagtt acgctcaata
    14761 atggatacag gaaaactggg ggctttaaaa atgatccaag cacctttcgg cagttacaaa
    14821 gaaccagacc ctaaaaaccg gttcttcaat ccagaattag ctggaggagc tctgttggat
    14881 atcggtacgt atgctgtatc tttcgctcgt ttctttttga gctctcaacc tgaagtagtt
    14941 gcctctacaa tggttccttt tgaaacaggc gtggacgaac aatccgtcac tatcttgcgt
    15001 aacaaagaaa atgaacttgc tgctgtcagc ttgacttttc aggcaaaaat gccaaaagtc
    15061 ggtatcgttg cctttgagaa cggttatgtg acgattgctg attacccgcg tgctgatcgt
    15121 gcggagatct tatttacaga tggtacaaag gaattcatcg aaagcgggaa tacatctgaa
    15181 gcaatgaatt acgaaataaa gaatatggta cacatgattg aaggtgactt gcccaatcgc
    15241 tctctcttct tgacaaaaga tgtcatcgaa atcttggatc aaatgcaagt tctatggaaa
    15301 aatatgtaat tttaaaaggt tgtgaaaaag ctgttctgca tcaagtaata agaacagcca
    15361 aacaaaaata gctcctccta tttttcgttt ggctggactt attaccgcag aggaaagctt
    15421 ttgaacaccg tttaagaaag aggttgtgag cctaccgttc agctccgagt cacaaggagc
    15481 aatttcaaaa aacagcttct catgtttgtt gaatattgtg acttgtgacc gaggagttga
    15541 caggagaaca ccgtttaaag aagaggttgt gaaatcagct ttttgacctg aatattagct
    15601 gaattcacaa cctctatttt tggatttttt gttgggagaa ttctgccttg atttcaataa
    15661 aacttttaaa agactgcaaa aactggaaca attctgctcg atcctcgaat tcagggcgac
    15721 tagtcggcag aggcatttgc cgatacaata cataaacttc ttcaatacgt gttaaaattt
    15781 gtctgccatc atttgactct gaaaatgttt ctgcagtata aatcaataaa ccatagatat
    15841 gttttccata ataagctggt tgctggattc tctctagatt ttccagcatg tctttaatca
    15901 cattggcctg tgctcttctc atagagaagt aagtttcgta gtatagcggc tgtctgagcc
    15961 agtagttttc ttgatgttct ctggcatctt cttggctttc gcgaatgaat gtcagtaaat
    16021 gttcgcattt gatctgcaca tcttctttat tttctgataa aagaaattct gccatttgtc
    16081 tcaaaatatt tcgaaattct ttttcgatct gtatttggtt ttccttcagc tgcttcgtac
    16141 gatctggcat gtaaacattt gcaagcaaag caaatactaa tccaatcgcc attaatcccg
    16201 cttcattgcc gatcagctgc caagacatgt tttcctccac taaataatga gtgaccaaaa
    16261 ccgaatttac tactatccct tcggttaatt tgaagcgaga ggcaagcggg atgaacagga
    16321 ataaaaaaag actgaagcca aaaatagtat acccaacagc aaaaaaactg aacagtgctg
    16381 ttgccgtagc taatataaag gctgcgattc gattcatgcc cgtacgcaat gtagagcgct
    16441 tggtatttcc tacacttaat aatgcaatga tccctgcagc tggccaatac aacagcgata
    16501 agctacccgc tgtgaccatc gaaaagaaga cactgatcac tgttttgact gttcgcattc
    16561 ctatacgcat ttacttcccc cttttttatt ttaattatac ttgaataatg aaaaactagc
    16621 tatcagacaa aagtttaggt atgatagtaa aaagaccaaa aaggagaatc tctatgcaat
    16681 ttggccgttt tcgactaggt atgcgtacga tcaaaagtgc cttagctgtt tttttatgta
    16741 tcttgttttt tcatttgact caacgaggaa tcccgatgat tgctgcatta tctgctgttt
    16801 tttctttgcg tcaggacttg actacaaccg tttcttttgg aaagtctagg atcatcggca
    16861 atacattagg tggtacatta gctatcattt atttttttgt caaaagctat tttcacaatg
    16921 attttttggt agaattgatc ttgcttccta ttctagttat tattgtgatc gtcgtgtcag
    16981 atggtattaa caataattcc ggtatcattt ccgcaatagc tacgttgttg ctgattgcgt
    17041 tgagcatccc tcaaggcgaa tccgctttgt atgctatcca acgtgtacta gatactttta
    17101 tagggacatt cattgcaatc ggtatcaatt tctttcttcg tcctcctgaa acagaaaaga
    17161 aggaagaact atcagaagat ttggtcgaac tccaaaagaa agaacgattg ctaagaacaa
    17221 atttacaaga gatagaagct aagatccaaa aacaaaagaa aaatagcgag gactaatttt
    17281 cttttgcaat aaaataaaaa aatggagaga agaactttaa aaagtcttcc tccatttttg
    17341 attgaacggt gaagtgtact actttattct tccttcatcg agttttgttc tgcctctttt
    17401 ggcgcttcat acatatttac ttggctagta gtcccacgtg tcgacaaatt ctctacgatt
    17461 tccttcaagt caagtcctgt tgtcgctttt agtgtttctt gagtagaaga aagcaaattt
    17521 gtggcataat ttgtcactcg gttcgctcca ctggtttctc ctgaactgct tcctgtatcg
    17581 acaacagaga ttttttcgat atttcctagc ggctgtgctg cttcgcgcat caattgcggt
    17641 agcatatcga taaccatact caagacagct gcttcgccat attccttgaa ggcattggcg
    17701 atcttttgtt ttgcttcggc ttctgctttt ccttttgcta gtgctgcttc ggcttctgct
    17761 tgtccagcta aacgtgtctt attggcttcc gcttctgcca gtgcttccac acggaatcgt
    17821 tctgcttcgg cttcagtcac ttctttgact ttttgagctt gtgcttcttg ttctttagcg
    17881 taccgatcgg catctgcttt tttcttcact tccgaatcat attgcttttc acgacgtgtg
    17941 atttcttttt cttccagttc gatttgtttt tgacgttcta cgattttaat ctgcatttcc
    18001 tgttcgatta cttgttgttg tgctcgggca ctttctaaat tgtaggcttg gtctgctttt
    18061 gctttagcaa catcttgttc ttgtttgtag gttgctaatt tcagttcttt ttcttttaat
    18121 gattctgcga tctctgtttg tcgctgtaat tcagctgctt gtgattcttt ttctgcttga
    18181 gcttttttga tacgcgtttc ttttagagct tccgcttctg ctatatctgc atctcttttg
    18241 acttgggcga ttcttggttt ccctaaagag tcaagataac cgtttttgtc tctgacctct
    18301 ttgatagtga aagaaacgat gatcaacccc atttttgcaa ggtctacaga agcgacttct
    18361 tgtacgcttt gactgaactt atcgcgattt tgatagattt cttctacagt catagaacca
    18421 agaatcgagc gcaagtgtcc ttctaatact tctcttgctt cattttccag ttcttctctt
    18481 gtcttgccta aaaactgttc tgctgctgta gcaatctctt ctacagatga accgattttg
    18541 atgatcgaag taccatcaca catcaccggt acgccttgtt ccgtatacac ttcaggggtg
    18601 gagacgtcca atttactcga taatagactg atccgattcg aacgttgaaa aactggcaag
    18661 acgaatgcgc cacctccacg cacaattttg attttgttat tgctttcatc aatgtgcaca
    18721 tttttgcttc ctaaataact tccactgatg atcaacgctt catccggttt tgctgtctgg
    18781 tacttcgcta caaagacgat cagcaacatc agtaaaatca aagctgcgat tgcgatcgcg
    18841 ataaaaacaa ctggtatttc catttaacac acgctccttt aagcttttat catgctttca
    18901 taaggcatga cataacagat tctttccttg atctcaatga tcaatacttt cgttccccgc
    18961 tcagctgtct gttcttgggg gctgtaaaaa caagctggac gactaatgga accggtaaca
    19021 cttttcaact gaatttctcc catacctcgt acagggatcg gtgtgatcac aacagctact
    19081 tgtccttcca gagttttttc agaagacgac atcgttgatt cggcatgttt catcggcatc
    19141 aatatataga aattaagcaa aaataccaac actatcgata tgcctccact agcaataaat
    19201 aaaaataaag atgattgatc tgttaaacgc tcacctagaa aaccaaataa gcttgtgaaa
    19261 gttaaccaag ggataataag catcggatca agcgggccat caaaatcgaa tacatctcca
    19321 aaaataatca ataggactgc caatcctgca caaatcagca atgtatacca ataaatcgtc
    19381 tcaagtgcga ttccccctat catatacacg cctccttcca tttctacgtc tatcatacca
    19441 atgtttgaaa attctgtata gcttctttta ccgactcagt ggtgtttttt ataggaaggt
    19501 tgtgtttatc gttgacaatt tgttaaattt ttgttttcat gttaaaattt tcacaataaa
    19561 ttctttcgag gtagcctatg tttccttttt ttaagaaaaa accattaaag ctccagaaca
    19621 cgatcatcct tgtcgtttgt ttctccacat tcgtttcttt gattgtttct gccatattga
    19681 tcaggaattt tattctttcg atgaaccgat ctagtgtgtc agataaaatc tctagcattg
    19741 ctaaaatcgt tgccaatgat aaactcatcc aaaaaaagct gcagactggt gacccgacac
    19801 atgcgattca aggaataaca aatgaaatca tgattgcatc gaatttagat tttatcgttg
    19861 tcatggaccc tgaaggcatt cgatattctc acgcagaccc aagttacatc ggtcttcctt
    19921 tctcaagtca tgaagatgtg aaaaaagtga ttggaggaca agaatttttc tctgaaaaag
    19981 aaggaatgtt agggttcggc ttccgctatt tcgtccctat ttattatgat caagagatta
    20041 ttggtgcagt ttgtgttggc ttaacaaaca acacgattga caatcaagtc aaagatggac
    20101 aaaaaatgat tgttttttca ttgattattg gacttagcgt aggcatcata ggcgccgttt
    20161 ttcttgccca aaaaatgaaa aaagtactgc ttggacttga accacaagaa atagcagaac
    20221 agttaagtga aaaaacgatt atcgaaaatg aagtagatga aggaatctta gccatctctt
    20281 ctgataaaac tatcctcttg atcaatacac ctgcaaaaaa cattttctac caaacagagc
    20341 agctattgga tttcgaagta ggaaaaaaat cagtgataat ctatatgacg ttttgtttaa
    20401 agagacgatt gagcatcaaa cgaccgttcg gactcaatcc atgtatttaa atgggataga
    20461 aactatttct agcgttacac ctctttttag caatgaccgt tttttaggag cagtcgcaac
    20521 tttacgaaat cgatcagaag taatgaaatt aatggaggag cttgggggga cgaaacaata
    20581 tataaactcc atgagagctc aaacccatga attcatgaat aaacttcatg tcatttctgg
    20641 tttgattgat ttgaagaagt atgaagaagt cacccatttt atccagcagc taaatcaaaa
    20701 ttataaaaaa gagattggcc aagtctcaag tctgatcaaa gtacctgcaa ttgccggttt
    20761 tttattaggc aaaataaacg aagccaaaga acaatctgtt gaaatgctgt tagaaagcga
    20821 ttcttttatc cctaaaatgg agatggatga ctccatccat tcacttttgc aagtgttagg
    20881 gaacttactt gataatgcaa aagaagccgt gctacaaaaa catgaaagaa acggacaggt
    20941 ccggattcat ttaaactatg acacagaagc tgaagtattc atcgtgaccg tctgcgatga
    21001 cggtgtcggg atatcagaag aaatctcaga aaaaatattt acgctaggtt tttcgacgaa
    21061 gggaatcaat cgtgggtttg gattgaatct catccattca atcgtcaaac gccacggtgg
    21121 atttttagaa ttttccaaac aaacaaatgg cggtacaatc gtctatctag aattaccaaa
    21181 aaaggaagat caaaatgatg acaaatgtcc tgataatcga agatgatcca atggttgcag
    21241 aattgaatcg tacttttgtg gaaagcatcc ctaatatgaa cgtaatcgaa agtttcagaa
    21301 atgtagaaga aggaaaaaaa tatttcagac aaaaaaacgc agatctgctg ctgcttgatg
    21361 tatacatgcc tggcgaaagt ggtatccatt ttttatcttg gcttagacag caaggaaatg
    21421 atatcccagt gattttgatc actgctgcag atgatatcga aaccataaag aatgtgatcc
    21481 gctacggtgc cttagattat ttgatcaaac cgttcacttt gcaacgtttt cagctggcga
    21541 tcgaaaagta tcttgctttc tctcagacaa tccaaacgac tgaaaaagcc gatcagaaat
    21601 tgatcgatca agtattcaac cacaccactc ccattcacga aataccatca ttcatcgatt
    21661 tgcctaaagg tctgtcaaaa ctgactttaa aaaaaataag tgcatttatt ctaaaagaag
    21721 atactatttt ttcaacaaaa gaactggctc aaaaaagctc actgtcacgt atatccgtca
    21781 agaaatattt gaatttttta gtagaacaag atatattgaa cgaaagaatc aaatatttgg
    21841 aaatcggccg gccgctaacc tgttatgaat tgacaaagaa tgggcggaaa aagctcacag
    21901 attactgttg agtcatcgaa ttatcccata caaaatagtc caagtataca gaagtaacaa
    21961 ctgtttactt ggactatttt taaacatttt attgacgaat atccatgttt tcttatctta
    22021 attgacgggc tttaggaaga gatacctcat ttttcgtttt tccagtttct attatttcac
    22081 gaaagttctc gaaacttgtc gaaatcatat ttgataatgc ctcatctgta tttgaaccta
    22141 catgcggggt tacaagaact ctagggtaca tttctactaa ttgctggata gcagggtctg
    22201 gaatcgtctc ccatggcttg aaggatcgga aaaaaacctc tgtttcattt gcaaaaacat
    22261 cggttgcaaa accagctaaa tgattgcttt tcaaagctct taaaatagct tcattatctt
    22321 gaagctctcc acgggctgta ttaatcaaga tgctaccttt tttcatttga gctaaaaatc
    22381 cttcattgat catttgatcg ttttcacctg ggatatgagg tacatgaata ctgacaatat
    22441 cgcttttggc taataactct tcaagcgagt ggaacgtcaa tactttttta gcagcttctg
    22501 tctgatgaat atcgtagccg atcactttgg ctcctagtcc cttaaacaaa acagcttccg
    22561 tcaaccctat cctgcctgtt cctatgatcc ctactgtgca atttctgatt tcacgactaa
    22621 acatttgctc atccactcga aaatctttga aagatgttcg gatcgtcgta tacgcagtat
    22681 ttctcaaaag catcatggca aaagtcaaag ataactctgc tatcgcattt ggcgaatacg
    22741 atggtacacg ggctactgtc ataccaaaat cagctgccgc ttgtagatcg atatgattga
    22801 ctcccacagt ccgtgtaaaa acataacgaa tcccatattc ctgcattttt gcaagattgg
    22861 tctcatctgc tatacaattt cccctcaaca atacagcatc atggtccttt gctgacacga
    22921 tattgtcatg tgtcaacagt tcttcataaa gactgagatc ataatggtaa atattcaatt
    22981 tttcaaaaaa atctatctcg ttcggacgaa caccgtaaca tgcgattctc atactttctt
    23041 cctccatttc ttatgaaaat aaacctatgc catgaatcat ttgtaataca acgatccata
    23101 caggtgtcag taccacagca aaaatagttg acagtaagga tgcattggag gctaaaagtg
    23161 cctccctatc aaaactgata gcataggctg ctgccactgt tgcagctggt gtagccatca
    23221 tgataacgat tgttgccagt gcttcaaaat tgactggtag aatattcgtt gccgtcaaaa
    23281 ctgctagaat cacgatattc aatgcaggta caaataccac tttgactaga ctgtaatacc
    23341 atgaagtttt ttcagatgca gcttttttga agcttacttc acctaatgtt gcgccgattg
    23401 ctagccacgc caatggtgaa cttaaaccag ctaaataatc catcggctga aatagccacg
    23461 gtgcagtctg gtcaattcgc aaaaacgcta cttggcttat ctctccttct gcacctgtaa
    23521 ctgacacttg tggcagatac ccttggaaca gccaaatgaa aaggccggca aaagtagcga
    23581 taatgattgg attgacgaac atcgctttga tatttttagc ttccatcttc aagccactca
    23641 tttttatgta tccataagaa tacaaaaaga ttcggtagcc aatattgaaa attgaggaat
    23701 acatcacgcc gacaggacca taaatcgcac tgacgatagg cgttccgaaa aaggtcgtag
    23761 aaccaaagat cgtcaggaca cgcaacgttg tttgcttatc ccctttatag cttaagaaaa
    23821 aaggttttga aactagaata agaataatat aaataactaa tccccaaatc aagacattga
    23881 ttccttgcat cagtaattct gtattgatat cttgcatgaa agctcgaaat gccagtgctg
    23941 gcaaagccac tgttaagacg actttcgata gaatttttcc aacagattca gaaaaaatcc
    24001 ccttttttct acaaacaaac cctaataata taataaaaac tgttgaagtg attgcactga
    24061 caatcgacat atctgtcaaa gtcgatcgaa aaatgtcaaa taagttcatc tttctcctcc
    24121 taattatgtt catttattca caataaaaaa agcttttatt ttgctaatac gtattaacat
    24181 ttttaatttt atctttacat tgttacttat tgaacaatag gaaattaaag aaacttttga
    24241 aacttatgta aagtgatt
//
LOCUS       DAIGWC010000039        23857 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.039, whole genome shotgun sequence.
ACCESSION   DAIGWC010000039 DAIGWC010000000
VERSION     DAIGWC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.039"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            172..516
                     /locus_tag="NOB74_001616"
     CDS             172..516
                     /locus_tag="NOB74_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCI1220809.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="NOB74_001617"
     CDS             517..936
                     /locus_tag="NOB74_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCI1220810.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1028..1378)
                     /locus_tag="NOB74_001618"
     CDS             complement(1028..1378)
                     /locus_tag="NOB74_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220811.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2665)
                     /locus_tag="NOB74_001619"
                     /pseudo
     CDS             complement(1344..2665)
                     /locus_tag="NOB74_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
     gene            2921..3487
                     /locus_tag="NOB74_001620"
     CDS             2921..3487
                     /locus_tag="NOB74_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1220812.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3632..3719
                     /locus_tag="NOB74_001621"
     tRNA            3632..3719
                     /locus_tag="NOB74_001621"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3664..3666,aa:Ser,seq:cga)
     gene            complement(3771..4976)
                     /locus_tag="NOB74_001622"
     CDS             complement(3771..4976)
                     /locus_tag="NOB74_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI1220813.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIEDKNIEFYTKEELIKFLEAIRNDDDERYLFFSLLAFTGI
                     RKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRLIVNTPKSKSGKRKIYLDNDLISLL
                     RKYYTKNKTIVTIQRENLIFHHDGLLYNPTVSRSWLNVIYKHHPELTKRITTHGFRHT
                     HASLLFESGASLKDVQERLGHADIQTTSNIYTHVTETQNKKVINNFVAFMKNSTQGES
                     KGESKNILG"
     gene            complement(5114..6002)
                     /locus_tag="NOB74_001623"
                     /pseudo
     CDS             complement(5114..6002)
                     /locus_tag="NOB74_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            complement(6089..6289)
                     /locus_tag="NOB74_001624"
     CDS             complement(6089..6289)
                     /locus_tag="NOB74_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220814.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            complement(6318..6740)
                     /locus_tag="NOB74_001625"
     CDS             complement(6318..6740)
                     /locus_tag="NOB74_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCI1220815.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            complement(6757..7179)
                     /locus_tag="NOB74_001626"
     CDS             complement(6757..7179)
                     /locus_tag="NOB74_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1220816.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQKELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            7470..7661
                     /locus_tag="NOB74_001627"
     CDS             7470..7661
                     /locus_tag="NOB74_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220817.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            7672..7938
                     /locus_tag="NOB74_001628"
     CDS             7672..7938
                     /locus_tag="NOB74_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220818.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALSQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            7950..8120
                     /locus_tag="NOB74_001629"
     CDS             7950..8120
                     /locus_tag="NOB74_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220819.1"
                     /translation="MGKFNRTLVFSAPLIIYALGLWGSRQALIGTIVYMLWIFIGLDE
                     AEYRAKKPVGRD"
     gene            complement(8179..8658)
                     /locus_tag="NOB74_001630"
     CDS             complement(8179..8658)
                     /locus_tag="NOB74_001630"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220820.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            8703..9410
                     /locus_tag="NOB74_001631"
     CDS             8703..9410
                     /locus_tag="NOB74_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HCI1220821.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAEN
                     WADLFWEDTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKE
                     LKDQLPSIPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMV
                     RNKIRVICNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMP
                     STATMTIIKQMELLEDE"
     gene            9589..9930
                     /locus_tag="NOB74_001632"
     CDS             9589..9930
                     /locus_tag="NOB74_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220822.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            9923..10669
                     /locus_tag="NOB74_001633"
     CDS             9923..10669
                     /locus_tag="NOB74_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HCI1220823.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            10675..11361
                     /locus_tag="NOB74_001634"
     CDS             10675..11361
                     /locus_tag="NOB74_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220824.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            11368..12201
                     /locus_tag="NOB74_001635"
     CDS             11368..12201
                     /locus_tag="NOB74_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HCI1220825.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            12218..13069
                     /locus_tag="NOB74_001636"
     CDS             12218..13069
                     /locus_tag="NOB74_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI1220826.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            13066..13425
                     /locus_tag="NOB74_001637"
     CDS             13066..13425
                     /locus_tag="NOB74_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HCI1220827.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            13440..13601
                     /locus_tag="NOB74_001638"
     CDS             13440..13601
                     /locus_tag="NOB74_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCI1220828.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERIKAVMVNETARKAINLHIVNL
                     RREIRRLEE"
     gene            13604..13903
                     /locus_tag="NOB74_001639"
     CDS             13604..13903
                     /locus_tag="NOB74_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220829.1"
                     /translation="MGKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            13903..14217
                     /locus_tag="NOB74_001640"
     CDS             13903..14217
                     /locus_tag="NOB74_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HCI1220830.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            14394..14705
                     /locus_tag="NOB74_001641"
     CDS             14394..14705
                     /locus_tag="NOB74_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HCI1220831.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            14702..14920
                     /locus_tag="NOB74_001642"
     CDS             14702..14920
                     /locus_tag="NOB74_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HCI1220832.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTAVGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            14933..15214
                     /locus_tag="NOB74_001643"
     CDS             14933..15214
                     /locus_tag="NOB74_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220833.1"
                     /translation="MGDMGEYWKDIKPHLKERRKQHVRKMGNSATKNIETLGFEFTHY
                     PNNHQFAINTHNGIIDYWGTTGTWIERKTKKRGKGIRSLRKYINQEDSK"
     gene            15211..15537
                     /locus_tag="NOB74_001644"
     CDS             15211..15537
                     /locus_tag="NOB74_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220834.1"
                     /translation="MNYTQQELTDLCPKHVAEFINNEVLPKYADGLNTAENVTDFMIN
                     DAIDRLIFLEIDCIAYYRLHAEVALIDPYIALSQNRKILVAYIDTKQILEGRDVEIEI
                     DEEEVG"
     gene            15534..15731
                     /locus_tag="NOB74_001645"
     CDS             15534..15731
                     /locus_tag="NOB74_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220835.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            15728..15937
                     /locus_tag="NOB74_001646"
     CDS             15728..15937
                     /locus_tag="NOB74_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220836.1"
                     /translation="MKIYVVKFGNKFYRSDERSIGANTLFIVDILQSARWFDSLEEAN
                     QVSRRLGGLTQVYELVTVDHEEVER"
     gene            15934..16221
                     /locus_tag="NOB74_001647"
     CDS             15934..16221
                     /locus_tag="NOB74_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220837.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKKRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMKAI"
     gene            16814..17281
                     /locus_tag="NOB74_001648"
     CDS             16814..17281
                     /locus_tag="NOB74_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HCI1220838.1"
                     /translation="MVLFDVKKYETPEAKDVDMDRTKHNVGVFLSAYLSARCRIGQPR
                     EPKVTASYSLVPPSTANNTFEAERMMIEREEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            17580..17921
                     /locus_tag="NOB74_001649"
     CDS             17580..17921
                     /locus_tag="NOB74_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220839.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDPRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(17914..18105)
                     /locus_tag="NOB74_001650"
     CDS             complement(17914..18105)
                     /locus_tag="NOB74_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HCI1220840.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSDNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDVTK"
     gene            18455..18667
                     /locus_tag="NOB74_001651"
     CDS             18455..18667
                     /locus_tag="NOB74_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220841.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQAKYFYDQL
                     ILQGFNDAQAMEFMMRTFSASNQQKE"
     gene            18674..18898
                     /locus_tag="NOB74_001652"
     CDS             18674..18898
                     /locus_tag="NOB74_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220842.1"
                     /translation="MRNYWYVSLSNKYPQPNADDPIRVVQSVQIKKKYSIIEMTREAT
                     PKEIDKYNLRYCGHGYFSEQNIQTNIERYC"
     gene            18925..19458
                     /locus_tag="NOB74_001653"
     CDS             18925..19458
                     /locus_tag="NOB74_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HCI1220843.1"
                     /translation="MVNLTPKQKAFADEYIKNGGNATQAAIKAGYSKRSARVIGKENL
                     TKPNIIQYINERLNPIEKKRKLSAEDALNELIDIWQGEVQISVSKQIDRLEKNKVIKH
                     MQYEYTPDLESKLKALDLYLKYKSLLSQTQLEKAQTEIKLMQAKLEQLQINSERSTEE
                     KLDELLEKISGELDGTS"
     gene            19445..20689
                     /locus_tag="NOB74_001654"
     CDS             19445..20689
                     /locus_tag="NOB74_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HCI1220844.1"
                     /translation="MALVDIYNPKQIDVLNKTIKNDWFITLLHGAKRSGKTKINNDLF
                     LFELRRVRKIADEEDIKEPMYILAGVSSATIQKNILQELYNMYSIEPKFDKHGNFKLF
                     GVKVVQAYTGNIGGVGAIRGMTAYGAYINEASLARQEVFAEIVSRCSGTGARILADTN
                     PDNPEHWLKKEYIDNSSKNIQSFHFELDDNTFLSERYRNNIKESTPSGMFYDRDIKGL
                     WVSAEGVVYRDFDASKHYIQSKDLPPLSNFYCGVDWGYEHWGSIVVIGETDDGTAYLI
                     EEHATQFEEIDYWVDVAKGIQERYGLRVPFYCDSARPEHVARFVREKINAKNAHKARL
                     SGVEEVAKRFKQDKLFICQDRVMKFRDEIYQYIWDKKKGEPIKEYDDVLDSVRYAIYT
                     HELLKKPKVNVNEKIKRIKRMF"
     gene            20702..22201
                     /locus_tag="NOB74_001655"
     CDS             20702..22201
                     /locus_tag="NOB74_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI1220845.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIEEFNTNNDIDGLNAELWLDMDKYGRAYEIIYR
                     DSDDTDYVDLANVFETFVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKS
                     ITYDETTLTAIELKNPQDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDT
                     ANYMTDLNDALLVISGDIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIY
                     KQYDVNGVEAYKYRVRKDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQR
                     LFKKGLMRRYRLLFSLKSSISEMDNSDLKGLRVIFTPNLPKAILEELKSLVDAGAELS
                     QETILGLASFVPDVQAELKRVNKETQKQIGIFDSDGEEVINNKKDETGG"
     gene            22206..23132
                     /locus_tag="NOB74_001656"
     CDS             22206..23132
                     /locus_tag="NOB74_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HCI1220846.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGLAELKRQAGILEMTIASSGYAKL
                     IELVINSSFLSDDVSFSDRLWMYQSELKSELDRLLVRSITMGKNPKQLASKLAEYLTA
                     EGRENTKFNTQRLMVTETTRVQVGIQERSYRDAGITQYIYIAEPTACKLCIPLNNQVF
                     DVADMQPGSNAPNMHPFCRCSTAPYIERISSR"
     gene            23259..>23857
                     /locus_tag="NOB74_001657"
     CDS             23259..>23857
                     /locus_tag="NOB74_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HCI1220847.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQQGNLPAGSQETPPEAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELAAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIKRENARQTPPNEGGQFTASKNTKETVAKLAAKNRII"
BASE COUNT         8475 a         3792 c         4765 g         6825 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattgaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg taggatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga cgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggcaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaatttttg aaccaggttg tcgcaatcac tggcatgtcc ataaagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat agtagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagtacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcgagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cctatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc aaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtagaccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataatg cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccagaatc gaagcaaata agggaccgtt taaaatcacc ttgtgccgat
     2401 aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg cttccgaaac
     2461 cgcctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata gttagcaatc
     2521 cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa aaaacacctg
     2581 taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga ggatgaatat
     2641 aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt taactataac
     2701 ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt aagggaaccc
     2761 attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga ctgaaaaaaa
     2821 atttaaaata taacgttttg agtaaaatgt ttgcaaaaaa tgctaaaaat agggtacaat
     2881 aaaacaacat atactgcagt aaagaagtgg gggagtttta atgagaagaa aagtctatac
     2941 caaggatcaa attctaaaag ctgcttatga tgttgttgca aaggaagggt ttaaaggatt
     3001 tactgcgaga aatattgcta aaaagatggg gatttcgaca cagccgattt atctggaatt
     3061 caaaaacatg gaagatttaa aaaatacgtt gctggattct atctttgaac aactaaaaga
     3121 agatgttttc cctattgaac gtactggtga taaaatcatt gatctcggtt tgaactatat
     3181 ctactttgca aaaaagcatc atagtcttta catggcattg tacattgatg aacatgggga
     3241 cggaaagaaa atgcatgatt tttcatacaa ttatttccgt gaaatagtta aagaagatga
     3301 aagatacaat caattatcgg atgaatatgt cgatgctctg catactggta catgggtagc
     3361 agtgactggc ttagcgtcat tgatgtcatc aaacatcatg catccaacag aagaacaaat
     3421 cattgcactg atcaaacgga caattgactc gattttagca ttagataatc ctgaaataat
     3481 cagatagtgt tctatcagta tgaatttgat cggtaagtcc gttggctgca aactgtcaat
     3541 ggactttttt gctaaaaaaa gcgatttctg ttatttatct attagaaata ggcttgacat
     3601 ttcgtgaaaa aagtttaaaa atagtactta cggaaggttg gcagagtggt aatgcaccgg
     3661 actcgaaatc cggcgaaccg gctaataccg gcgcgcaggt tcaaatcctg taccttcctt
     3721 atatatcaac gattagacac gatttcgatc gtgtcttttt tgttgtatat ttagcctaaa
     3781 atgttttttg actccccttt tgactccccc tgagtactgt tcttcataaa tgctacaaaa
     3841 ttattgatga cttttttgtt ttgagtttca gttacatgag tgtaaatatt tgaagtagtt
     3901 tgaatgtctg catgccctaa acgttcctga acatctttta aagaagctcc tgattcaaaa
     3961 aggagagagg catgagtatg tcgaaaacca tgagtagtga ttcttttagt caattctgga
     4021 tgatgcttat atatgacatt aagccacgaa cgtgaaactg tagggttata gagaagacca
     4081 tcatggtgaa aaattaagtt ttccctttgg attgtaacga tcgttttgtt ttttgtataa
     4141 tactttctca ataaactgat caaatcattg tccagataaa tttttctttt tccagatttt
     4201 gatttaggag tatttacgat caatcttcct tgataacctc ttgttacagt tttattgata
     4261 ttgagtgttt tgctcttaaa gtcaatatcc gaccaggtca gagcaaaagc ttctcctttt
     4321 cttatacctg taaaagccaa tagggaaaag aataaatatc tttcatcatc atcgtttctt
     4381 attgcttcta aaaatttgat taattcttct ttagtataaa attcgatatt tttatcttcg
     4441 atatctagag cttctccacg tggaatagaa actaatttca taggattgct agttataatt
     4501 tgtaaagaag cagcgtaatc aaaaacatta gatgtgtaat tttttatttt cttaaaaatt
     4561 ttaggatggc tatcggacca agtgtttact gcttcttgac agaaaaaaac gtctattttg
     4621 tcaatgaact tatctccaaa cacttttaag atgtgtgtgt caaaaatttg tttggtggag
     4681 gaccaagtgc tttctttaac tgtcttttta taattttcaa accataagcc gtaaacatat
     4741 tcgaatttct tgctcttttg agctgtagaa gcttgcagtc ctttttcctg tatatctgcc
     4801 tccaatcttt ttaaagctct ctcagcggct aatggcgtac taaaacctcg tctcgttgtt
     4861 tttctttttt ttcctgttag aggatcaact cctaagtaca gactaaactg atatttttct
     4921 tcgccttttt ttgttaagtg ctttttaatt cgtttatcaa tttctttttt tgccatcttt
     4981 atctttcctt tcgtacgttt gttcggttgt acagcggatt tcgagatggt aaaatagggt
     5041 acaacaaata gacctacttt accgtagctc tttgcacatt tgcgttcttg gtcgggcggc
     5101 aaatgtgctt tttttatttc actcttagtt cttgtcctgg ataaagcatg tagttgtttg
     5161 gatccatacc gtttaatgca aacagttgat ctaccgtaat tccagctcgt tcagctattt
     5221 gtttggtccc ttcaccaggt tgcaaagtca aggtttcggt ttcagatgaa gaaggtgccg
     5281 ttggttgagc ttgattagct ggtacataat cttgtggtac tgattgctcc gttgaactgg
     5341 gagtgggtga aacttgttca acacttgaac taggagtagc ttctgcatag ttttctacac
     5401 tttcagcaga gtaagtacta ctagtttcag gaggcgtatt ctgcgcaata gcagcttgtt
     5461 ctacagtact agaagatgca atagtacttt ctgttgtagt cgaagatgat tgttcgttgc
     5521 tacttgttga gctagtagtt gttctagatt ctttagtttt tttccttttt gtagggtttc
     5581 aaaactaatt tctcattatc atcagatttg ttaggctttt ctggagttaa aataatattt
     5641 ttatcttctt tgctgacagt atatttggca tcattatctt tgtctttatc atctttccaa
     5701 gtcataacat cgccttcaag tgtatactca aatttgtaat tcatttggtc gactaagctt
     5761 ttagcaaatt cttctcccat agcctcccaa tcgttacttg aagttgattt catagaactt
     5821 gtgtcaacac taaaagatac gacgtgatca gaaaatgata cgatcatatt aggttcgtca
     5881 tctttggttg cttcaatcaa ccaatcatta gcttttaaat cttctgtagt tactttttta
     5941 ccacaagcag tgaaaagtaa cagagaagca aaaactaata aacttgttat tacttttttc
     6001 attttttatt cctcatttct atgatatgat ttttattggg gaatcttaga aataaggttt
     6061 cgagtccgtg ttgctgcacg ggcttttttt atttaaataa atcccaaaaa ctgaatgtag
     6121 ttttcttgta tactttattg taagcagcct tttttgggtc tttaatccag ccgctacctt
     6181 ttttcccata accaggaata actgcttttt ttacttttct ttttgctttt ccagtggttc
     6241 tagcgcttat ggattttttt atacttggtt ttctcattcc tattttcatc tatatcctcc
     6301 ttacgttgta ttataattca caagaaacga tcgaattcat ctggtaatcc aaagcagacg
     6361 agcttttcat attttgtcat atgatcaaag ccgtctaaag ttggatcaat agtcagatga
     6421 gttgcgaaat aatttgcttc tttttcaatt tttaattcag atactagcgt ttttttagac
     6481 aacataggtg tgttttcatt cggatgcaaa acacagtggc ctaattcatg actacaagtt
     6541 atccattttc ccatctcatc taaactagaa tttatgtgga tcatttttat ctgtttgaat
     6601 ttactatagt aaccataaat ttctcccaaa tcttcttcta aaactagtat cttcaattct
     6661 cgtgcaattc taaaaggatt gcgtgtttga tatagtttta ccagcttatt aattttgtta
     6721 tcaatttgag gtaaatacat aaacaacgta ctccttttaa tcgcgatatt ttttaggtgt
     6781 gtattttttc ttagcttcta ttttagctat tcgcaaagca ttctctaaag aaataatgag
     6841 agcttcacgt gtcgcttcac tcatttcatt atctttcttc gaaaaagcca ttccatcagc
     6901 attagataaa tcgtcgatta atgactgcaa ttctttttgg atatcacgct cgtctttttc
     6961 tgttaaatca tagtatcttt ttttctcagt acgtcctagc aaataatcta cagatacgtc
     7021 gaagtagtca gcaatttctt gtaacttttc ggcagttggc tgttttcctg cgtttaaact
     7081 ataaaagtaa ttctctccgt acttcaaatc tttagcgact tgttgaaggt ttttattctt
     7141 gtttttcgct agttctttta ttctttcaaa tgttgtcatt ccaacgttcc tttccaacac
     7201 gaaaaaataa tttacgaaaa agagtaaaaa tagctttaca attttacgat atagagttat
     7261 tatttatccg taagttaatt tgatagaaaa aagcaaacta aaaacacacc ttatagcata
     7321 aagtttggcg accaagtgca aataaaaggt tttgttatag gcttatttct ctatgtattc
     7381 attttactct atagtgtaaa aatgtcaatg gaaattatat tttttctatc attttaactt
     7441 acaaatttat aaaaaaagga agtgggttaa tgtcaaactt ggataacggt cgtgcggcga
     7501 tcaaagagtt tatgaaagag aatggaataa ctatggatga tttggctact gcttatggtc
     7561 acacgcgtgt acgaatgcaa caaattcttg atggacactg gagtggacca aaggcaaaca
     7621 gaactattct agagatcatc cgtgattaca gaattcgata ggaggcaagt catgaatatt
     7681 ctaagcgaag agtttttgac tcgtttaaga attgcaattg ttgaagttgt aaaggacgca
     7741 cttagtcaac tttcaaaaaa gaatttgtca gaaacacgat atttaaaaaa gatcgaagct
     7801 agaaaatatg tgggaggtgt aaacgatcaa ggttttgaga agttaatagc tcacggttta
     7861 aaagaaattc gtatagatgg ctttttaaga tatgacaaaa aggacatcga tgaactgatg
     7921 gctaaataca aaatttaaag gaggtcaaca tgggaaagtt taatcgaaca ttagtattca
     7981 gcgcgccact aattatctac gctttaggtc tatggggtag tagacaagca ttaatcggca
     8041 cgatcgttta catgctttgg attttcattg ggcttgatga agctgagtac agagcgaaaa
     8101 agccagtcgg gagggactga ctaaaaaagt ctaatgtcta taagaaaggt ttgacaataa
     8161 atgaaagaat tatttttttt aataactttc atcatttttt ctatcagtgt tttctacatt
     8221 aacctttgcg ttgctagatt tgctttgaaa agttttagga acagcaaacg aaaatagagc
     8281 tataaaagat acgaatgtag tagctacgtt aaattgctct ttagaaaacg tcaatgtcat
     8341 tggaatgata attgatatcg atgagaaaat ctttgcgata ataactatcc atttttcaat
     8401 tataaacatt tttaaattaa gcaccattag acaaaatgta gttcctatat agaggataaa
     8461 tgaagataga aataaacata ttagtccagt tttaaaaaaa gagaagtaat ctatgtgggc
     8521 aaattctgtt aatatgcttt tttgatttaa cacaatcaaa ctactgttgg acaaaaatga
     8581 cagtaaggaa agagttgctc cgattactaa ataaaaaata gttgttaaca atattatatt
     8641 atcaattttt ctgctcatgt tttcacccca ccagaattat atcaaaaagg agagaagaaa
     8701 taatgcaaga attagtaatt ttgaaaaata aagaagctgt gactacgagc ttacaagttg
     8761 cagaaagctt cgataaaaag cacagacatg ttttgacggc tattgatgaa ctaaaagagg
     8821 gggttgccga aaattgggca gacctatttt gggaagatac ttatgttcat cctcaaaata
     8881 aacaatcata ccgaattatt tatatgaata gagacggctt ctctctatta gcaatgggct
     8941 tcactggtaa gaaagcttta agttttaaac ttcaatatat tgaggccttc aacaagatgg
     9001 aaaaagaatt aaaagaccaa ttgccatcaa ttccagcaac taaacgagaa atggcattac
     9061 ttgctctagc tgcaaacgaa gaaacgaatg aaagagtaga cgctatcgag tctgatttaa
     9121 acgatttgaa gaacaatcaa cttctagctg aaccagatta ccgaacaatt tctaatatgg
     9181 ttcgcaacaa aattagagtt atttgtaatc agcagcattt aaatagcaaa gcaaaagcag
     9241 aattgtttaa agacttgaat ggcggaatta agcgaatcac tggagcagta gctagaaatc
     9301 gtatcaaggc aaaacagttc gatgatgtta tcgattttat taacaattgg atgccttcta
     9361 cagcgacgat gacaattatt aagcaaatgg agttgttaga ggatgaatag agctgaagcg
     9421 ctaaaaatag gcgtaataat tgctaatcgc tggtggagac acaataaacc aaacatccta
     9481 agccaacaac atattgataa gcaaaaagca tggcaacaaa taaaaaagtg actcagccga
     9541 ccaaagcaat gagtcacaaa gaaaatacat ctaaggagat gttaccacat gaaaaaagaa
     9601 ctttccactc tagatcaata tttgactgat cctagttggg gcaaatcgaa tatcaaggaa
     9661 acaagcaatc gaaaaatcag acgtaatctt ttgacggatg aagaactagc atgtgatcaa
     9721 gacgatttgg gaaattttgt gagtatttgg gatcatgtct atcttatcca tttatcgagg
     9781 aagtccaaaa aaactgaata tatctatgtc atcgaagatg gcttgattga tgcgctagaa
     9841 gagtatgaca gagataactt gattgatatc tcttattacg gatcaggtaa gaaatacatt
     9901 gctgaaatgg aggcagaatt tgatgagtga aaaggaacaa cctttgaaaa atagaagtga
     9961 taatacgctt tttaatacct tatacaaaat aaatgtgaaa gatgttactg aaaaacgaaa
    10021 taacctcact tatctttcgt gggcatgggc ttgggcagaa gttagcaaag tgtgtgaggc
    10081 agtagattat gaaatctatc atgatccaga aacatatctg ccgtatgtct ttgataagaa
    10141 aacaggctat atggttttta ccagtatcac agtcaacgga gtaaagcgtg acatgtggtt
    10201 accagtcatg gatggtgcaa acaaggcaat gaaagatgag ccatatacct acgaagtcaa
    10261 tgattatcag tggaataacg aaacgaagaa aaaagagatt gttggaaaaa tcgaaaagcg
    10321 agttgaagca gcaactatgt ttgatatcaa caaaacgatc atgcgctgtc ttgtaaaaaa
    10381 tctagcaatg tttgggctag ggctatatat atttgctggc gaagatatgc cagaagatgt
    10441 ctcgatgctt gaaccagcta ctcaaagaag caaaaagcta ttcttggatg ctttacaact
    10501 ggttgctaac aagtacgaaa aatcaattga tgaagcaatt gttgcattga ctgatgcggc
    10561 ttctataacc gctgatgaca gtaaatggac caagagagac ttgggcattc taaaacgagg
    10621 cgttaactgg attgaagatc agtacagaga agaaacaaaa gagaagtgat atgagtgttt
    10681 aaaccattga tcgattcata ttcagcggtt ctgaaaaagt tcaaaggaaa agacataggt
    10741 gcaacgatca atgaagaagt gaacattgat cgactaaaga cgatgtatga cggatatgat
    10801 ggcgatcgga ttattgaagt tcgatttatt gatccacgtc gatttactgt gcagcaacga
    10861 aacttcatct atgcgctgat aggcgatatt ttcatcgata caggcatgcc aacggacttc
    10921 tggaaggaat tcttttactt ccgttttgaa ggcgtcacag ggcgcaaaat aagcctcaaa
    10981 gacgaatcga atacaactgt gagtgatgct aatgtcttag caaatatcat cttagatttc
    11041 atctttgaac atcatattcc tttcaaagaa ggctatgaga ttttaccagc gaatcaagaa
    11101 tattacttct acaaatgcat cacaaaaaga gtctgctgca tctgtggcaa aacaggagct
    11161 gacatcgatc actttgacaa agcgctagga agacgaaagc gcaaagaagt tgatcattca
    11221 gagtacacat ttgcagcact ctgcaggatt catcacacgg agaaacacaa tataggtgtg
    11281 atcaatttca aaaataaata tcaaatcaaa gggatcaagt taaaccagga aacaattaag
    11341 aaacttagaa taggagggta aaaaatattg tctgacaaca aacgctacta ctatttaaaa
    11401 ctaaaagaga attttttcga tagtgacgag atggttctct tagaaagtat gccagatggc
    11461 tatatttatt ctaatattct tctcaaactt tatttaagaa gtctaaaaca cgaaggtaag
    11521 ttgatgttta atgacaggat tccatttaac tctacaatgc tcgcaactat tacaagacat
    11581 tctgtaggag tcgtagaaaa agcggtacaa attttccgtg atttgcagct tattgacgta
    11641 ttagataacg gagcaattta tatgtctgat atacaaagtt tcattggaaa atcctcaact
    11701 gaagcagata gaaaaagaga atacagaaag aaaatagaag aggcaaaacg gaatttaata
    11761 actggaggac aagtgtcgga caaatgtcca gacaaaacta caccagagtt agagatagag
    11821 atagagaaag atatagatat agataaagaa gaaaagaaag gtaagtattc tgacgaacac
    11881 ttacgccttg ctaaaaaatt gcaaagtaat ttaactgaag attttccaaa agaaatgaac
    11941 aaagtagata tcgaaaaatg ggcagacaca atcaggttga tggaagaaag agataaagcg
    12001 tctatagaag cgattgagta tgtgatcaat tggctaccta caaatgaatt ttggtttgga
    12061 aatattagaa gtgctaagaa attgagagaa aaatttgaga agctcaaatt cgaaatcaaa
    12121 gcagacaaga ataatcataa aaagcaaagt caaaaactac agtacagcaa tcctagtgaa
    12181 tatgacgact tgccaattta aaaaggagat gcatcacatg gaaagcctag caaatgctat
    12241 ggagaaacta ataagaagag tattagtgca aagcgggaaa tgtccagaat gtagcgaacc
    12301 tttgtatagt tggcgagcta aaaataagga tggttcagaa cgttgtaaac caacatgcat
    12361 gagttgtggt tataaagcgt tacgtgtgaa agaggatata cagaccgaac ggatatataa
    12421 cgacagctta aaagcacgag cgttgagttt ttttcaaaat ggttcggtat taacagataa
    12481 aactttgttt aaatgcaaaa tggagaatta tcacgtagtg gaccaagaaa cgaaaattgc
    12541 tttagaaaga gctaaaagct ttgtaaatga tgtcttactg aaccatcctg cacatttcat
    12601 tctatcaggg aaatcaggaa gcggaaaaag ccacttgtca atggcgacag cttgggaaat
    12661 acttgagcgc tcaaattatg acaagaaaat actttttata agctatcaag agttattaga
    12721 gcaaataaag ttttcttata acaatgctga actgagaaaa gaaattgaag gatcgcttat
    12781 agccgatatc aaaacaactg atttggtggt ttttgacgat attggagctg aattaggtag
    12841 cggggtatca aatagtaggc agtttacaaa caacacgtta aacacgctct tagaagccag
    12901 acagaacaag gcaacgatca tcacaacaaa cttatccggt cctgaactaa gagaagccta
    12961 cggcgaaaga attgtttcta gaatatttaa gaattcagaa ggttatgcgc tgaaattcca
    13021 acaaacagca gacaagcgca taaaaccagt gaaaggtagt atcgcatgaa taaataccgt
    13081 aataagaaaa ctgttcatcg aggtatcaag tttgattcta tcgcggaagc agagtattac
    13141 gatttagcct tgtggcaagc agaagcgaac ggctggaaag taaaacttca ggaaagattt
    13201 gagctgatgc cgaaatttga actagatgga aaaaagtatc gcaagatcga gtatattccc
    13261 gacttcacat tttataaaaa cggcaaactt gtcaaagtcg tagatgtcaa aggaatgcag
    13321 acaaaagact ttaagatcaa ggcaaagttg ttctgtcatc aatatcaagt gccgttgata
    13381 ttagctaaaa aatatcggaa tacgttcaag gaagagcgtt tttaacgagg tggtccatca
    13441 tgacaacaga agaagtgatt caaatgcgta ttcgaagcct tcaacgtgag attgacgatc
    13501 tggaacggat aaaggcagtg atggtcaatg aaacggcgag aaaggcaatc aatttgcaca
    13561 tagtgaattt aagaagggaa attcgtagat tggaggaatg agcgtgggta agaaagcagc
    13621 aatgaaacga atcattgaac tgacacattc tgagaattgg caagaagaca aagaaatagt
    13681 tgcagaagtc caaaagctcg gtaaatcaat gtggactgaa aagcctaaac ggaaaacgcc
    13741 gagaaaaatt gcaatctggc atggtgatcg aattctagta acgggtacag ctgaacagtt
    13801 atctgaaatt actggactga gcaaaaacat catctgggat agagctagga gcttatggat
    13861 tgattcaaag gggcgacagt ttaggtatgt ggaggagaaa taatggatct cattacacaa
    13921 tacagtgata tcatcctcaa gaaaatcatg atgaagattc agaaagataa aaaagcaaaa
    13981 gaacgagcgg aattagttaa gttggaaatg gctgaaacag gagcaggagt gcgaagtagc
    14041 aggcattgga aagcagcagc aaacattgaa ttttattaca acgaaattca aaaagggttc
    14101 gatcagatgc gtgagctgga tcggcaaaca aattggagca agaaacttca tcaggatcgt
    14161 ttcaaatttg tagaaaagta tagagagata ctgaatgagt atttcgagga ggactagatg
    14221 tttaattcaa cgttagcgtc aattcacttt ttattctata taacgatatt tgtagctata
    14281 ttaattaatg cgataaaaag cggtttttta acaccaatcg gcacaatttt aacattagct
    14341 tcatttgtta caagttgtat tatccaactt aaatatataa aggagaatga ataatggacg
    14401 aactaatcac aaaagtagag cagtgggcta aagataaggg attggatcaa gctgattcca
    14461 gcaagcaaat gttaaaaacg atcgaagaga tcggggaagt tgccgcttct ctagctagaa
    14521 aagatgaaca tggtttaaga gacggaattg gagatgtagt agtaaccttg attattttag
    14581 ctatgcaaaa tgatatggat ttgtacgagt gtctgaacca agcatacaac gaaatcaaag
    14641 gacgcacagg aaaaatggta gatggtgtat tcgtgaagtc gagtgatttg gaggacagca
    14701 aatgatcagc ctaacaatat tttggtgtgt aattggcggc ttactagcga tgttaggagc
    14761 atacctcatt tacgagagtg caaaaggcaa aaaatataca gcagtaggga ttattttgtt
    14821 tgttgtcgga attttagttg cgattggtgc agaaataaat ctttatttaa acggtacgac
    14881 agaagagttg atgtggtttt tattgtggac aaggagatag gaggacagcg aaatgggcga
    14941 tatgggcgaa tactggaaag atattaaacc gcatctaaaa gaacgtagaa aacaacatgt
    15001 cagaaagatg ggcaattcag caactaaaaa tattgaaacc ttgggatttg aatttactca
    15061 ttatccaaac aatcatcaat ttgcaattaa tacccataat ggaattattg actactgggg
    15121 aactacagga acgtggattg agcgcaaaac aaaaaaacgt ggtaaaggga tacgtagttt
    15181 gaggaaatat attaatcagg aggacagcaa atgaactata cacaacaaga actgactgat
    15241 ttatgtccaa aacatgtagc tgagttcatc aataatgaag tcctgcctaa atatgcagat
    15301 ggtttaaata cagcagaaaa cgttacagat tttatgatta atgatgctat tgatcgtttg
    15361 atatttttag aaatagattg tattgcttat tatcgtctac acgcagaagt tgctttgatt
    15421 gatccgtata ttgctttaag ccaaaatcga aaaatactcg tagcctatat tgataccaaa
    15481 cagattttag aaggcagaga tgtcgagata gagatcgatg aggaggaagt gggatgaaag
    15541 catacacaat caagttttat ggaaataaaa cctatgtata catcctaagc ggtctcagac
    15601 ttgattttag aggctattca aaagaagacc ttttagaatc cttatatggt tacggatatt
    15661 taaatgaaga tgaactaata agcttagaga aatttacaaa tgcttggacg attgaggagg
    15721 aagcagaatg aagatttatg tagtaaagtt cgggaataaa ttttatagaa gtgatgaacg
    15781 ctctataggg gctaacacat tattcattgt agacatactc caaagtgcga gatggtttga
    15841 tagcctcgaa gaagctaacc aagtttcacg acgacttggt ggattaacac aagtatatga
    15901 actggtcact gtcgatcatg aggaggtaga aagatgaaat taaaagacgg attttacgct
    15961 agtagtcatg gtatcggcgg tttaatgcta gatatgccga caaagaatcc taaaaaacgt
    16021 aagaaaccaa aattcaaagt cggtgacatg gttcgctgcg aagcagaagg gttcatctat
    16081 ccatttcgtg gatatgtaga acacgtctat aatcactcag cgatcattcg tattgaaaac
    16141 acgatggaat gtgataagtg gttagcgaaa agcaaagaga atttagctgt agcgagattg
    16201 gtggatatga aggctatata aacagcgaaa aaatgtactt ctaagagaaa aatttatttt
    16261 ttataaaaat aggaaagtat cattatgaaa aagaccacag agataaataa acctaccaca
    16321 taaaaaatga atatttcttg cgattcaata taggtatatt taacaatttg tacaataaaa
    16381 aatactatag gtaaaaaaga taacatgagg agcttatttg ttctagagtg tttgacaaag
    16441 taacaaaatg cgacgatacc aatacaaacg ggaatccaaa ataacagcat gctccacata
    16501 gtcactcaac catctcctat acgctttatt atcaattaga taatatcatt tttcgtaata
    16561 aagataaaaa aataagtaag gcttctcatt aaaatataaa aaagacagcc gaccactggc
    16621 tgtccttagc agaatattga aatagtgagc catctgtttt ccgccagata gctcaacatg
    16681 tatatgggta acgagtgcaa cctcgctact tgaaaagctt agcataagca tgggtataaa
    16741 aaaagccgga ttcctccgac cttaattaat aattctgaca caattattat atcataaatg
    16801 gaggaatcaa tggatggtac ttttcgatgt aaagaagtat gagacaccag aggcaaaaga
    16861 tgtggatatg gatcgcacaa aacataatgt tggtgttttt ctttcagcat atctgtcagc
    16921 tagatgtagg ataggtcaac ctcgggagcc taaagtaacg gcatcttact ccttggttcc
    16981 accttctaca gcaaataata catttgaagc agaacgaatg atgattgaga gagaggaagc
    17041 gcaagaagaa tttgagtact tgcacaaatt atttgttcgt ggctattcag caattcagca
    17101 tccgcataaa cctgatgtaa cagaaaggcg caagaagata ttctatgatc gttatatcaa
    17161 tggtctgccc atttatgtaa ctgctcaaag gaataatact agcgaagaat cggttaaagt
    17221 agaatcaaac agaattatca tccaatttgc ttcatcgtta gaactggttg cttttaagta
    17281 gccagttttt acacttttta taccctttga ttacccattt ggtttccatt ttataccttt
    17341 tttataccaa tcacttacct ggtaaatgat ttattatgat agtgtcgaaa gattagtgat
    17401 aggtctgaga caaaataata ataaaaggaa catcgtttta ttattgtttc acaattaagc
    17461 ttcgatagac agcaacggaa atattaagaa taaggatgtg aattccaact ccttctaaat
    17521 tgttcttatt atctatcatc cgttgctgtt tattaattta tgtattggag ggaaaacgaa
    17581 tggaagtcga gcaaataaag tatcaaggta tggatcggga acggttgatt gatattattg
    17641 agcaacaacg tttagaattg atccaaaaag aagctgtatg taaagagtac aaaaaacatt
    17701 tagaacaagt aattgagtat cattcagtag aaaagtacag atcagtggtg caaaaaaata
    17761 gagcaacgag tcctgatcct cgtcaagatg tatcgattag tatcaagacg ccagtattta
    17821 attctgttaa atcagaaaag ctagaaagta tctcaactgc tttggtagaa aaagcagctg
    17881 aaatgaactc cctagcaaat gaagttagtc gtcttattta gtcacatcga taacttgaga
    17941 gtctttggtg attccgtttt ttatagaatt aatggtttgt tcagcggaat atttagtcaa
    18001 gtatgtttcg ctagttgcta ctacttcatt gttatcggac ttaataacga agtaatattg
    18061 gccattagtt gcttctctta taacaaagta caaatttttc accacctttt aatttatttc
    18121 agcggaccac tcgctgataa ataaaattat acacttagta tttattttca caatattaat
    18181 ttgtcactgt ggcggaaagg gtagacgcta agcatgtgtg ttaggtcaat gcttcggcaa
    18241 ccatgcaagg ttcgattcct tgccagtgac tttggcaact gagggttgga aatgggcgct
    18301 caaagtacac gagcaaggcg aggtcgatag taatcgatgg aatcggtgta ggttgcttga
    18361 tagaactata actgcatctc gtttatgagg tgtagttttt acatattaga tcactcatcg
    18421 agtggtcttt ttattttgga aggggagtaa aaaaatgaac gaaaaccaat taagagagtt
    18481 gtttaaaacg aatgaagcaa acaaaacaat ggaggcgaca ttctacgaaa ctcaaaaaag
    18541 cttagcgtta atcgcaaaac aagctaagta tttctacgat cagcttattc tgcaaggatt
    18601 taatgacgca caggctatgg aatttatgat gcgaaccttt tctgccagta accaacagaa
    18661 agagtgatac gtaatgagga actactggta tgtatcatta tcaaataaat atccgcaacc
    18721 aaacgcagat gatccaatta gagttgtcca gtcagtccag attaaaaaga agtactccat
    18781 cattgaaatg accagagaag ctacgccaaa agagattgat aagtacaatc ttcgttactg
    18841 cggccatgga tattttagtg agcagaacat acagacaaat attgagagat attgttaata
    18901 aaattgaaag gtggtggctt gaatgtggta aatttgacac caaaacaaaa agcttttgcg
    18961 gatgaatata taaaaaatgg tggtaatgct actcaagccg ccattaaagc aggttatagc
    19021 aaacgatcag caagagtaat aggtaaggaa aacctaacta aacctaacat aatacagtat
    19081 attaatgaac ggctaaatcc tatcgaaaag aagcgcaaat taagtgccga ggacgcttta
    19141 aatgaattga tagatatttg gcaaggagaa gtacaaataa gcgtgagcaa gcaaatagac
    19201 cgcttggaga aaaacaaggt tattaaacat atgcaatatg aatatacacc agatttagaa
    19261 agcaaattga aagccttgga tttgtatttg aagtataaat cgctgttatc acaaacgcaa
    19321 ttagaaaaag ctcaaacaga aataaaatta atgcaagcaa aattagaaca attacagata
    19381 aactcagagc gttctaccga agaaaaactt gatgagttgt tagaaaagat tagtggtgaa
    19441 ttagatggca ctagttgata tttataaccc aaagcaaatc gacgtgttaa ataaaaccat
    19501 taagaatgat tggtttatta ctttattaca tggagcaaaa cgttctggaa aaacaaaaat
    19561 aaacaatgat ttgttcttgt ttgaattgcg acgtgtgcga aagattgccg atgaagaaga
    19621 cattaaggaa ccaatgtata tcctagcagg agtttcaagt gcaacaatcc aaaagaacat
    19681 cttacaggaa ctatacaaca tgtacagcat agaacctaaa ttcgataaac atggaaactt
    19741 taagctattt ggcgttaagg tcgtacaagc ttatacagga aacattggcg gtgttggcgc
    19801 aattcgtggt atgacagcat atggcgctta tatcaatgag gcatcgctag ctagacaaga
    19861 agtatttgct gaaatcgttt cacgttgttc aggaacagga gcgagaatac tagctgatac
    19921 aaaccctgac aacccggaac actggctaaa gaaagagtat atcgacaatt caagcaaaaa
    19981 tattcaatcg ttccactttg aattagatga taatacattt ttatctgaac gatatcgtaa
    20041 caatattaaa gaatcaacac caagcggcat gttttatgat cgtgatatca aaggtttatg
    20101 ggtttctgca gaaggtgtcg tttatcgtga ttttgatgct agcaagcact acatccagtc
    20161 aaaagactta ccacctttga gcaactttta ttgtggtgtt gactggggat atgaacactg
    20221 gggttcaatc gtagttatag gtgaaacgga tgacggaaca gcttatttaa tcgaagaaca
    20281 tgctactcaa tttgaagaga ttgattattg ggtagatgtg gcaaaaggca ttcaagagcg
    20341 ttacggctta cgagtacctt tttattgtga ctctgcgaga ccggagcatg tggctaggtt
    20401 tgtaagagaa aagattaatg ctaaaaatgc tcataaagca cggttatctg gagttgagga
    20461 agtcgccaag agatttaaac aagataaatt gtttatctgt caagatagag tgatgaaatt
    20521 tcgggatgaa atttatcaat acatttggga caagaaaaaa ggcgagccaa taaaagaata
    20581 tgatgatgtg ctagactccg ttcgatatgc gatatatact catgagcttc ttaagaaacc
    20641 aaaagttaat gtcaacgaaa agattaaacg tattaaacgc atgttttaag gagtgtgaaa
    20701 aatggataag gtaaacgagt ttgaatacgg agctgatata cattattcta atgacgtgaa
    20761 cacaaattat gtaaagttta gcgtagactc aaatcttcac tatagattta gctcagcaga
    20821 agatttactt aacgatttag atactttagc agcaatgata aaacatcatc atgaatatca
    20881 ggtaaaaagg ctaagtgtat tagatgatta ttataaagct agaaatacaa atatcatgga
    20941 taaccgtagg cgcagagaaa aagaaaaagc ggatcaccga tcagcacata actttggaaa
    21001 agttctttgt acgtttgatg ttgggtacaa cacaggcaat cctataaaag tgcaaatcga
    21061 ggacacaaat caacaaaaag aaatcgaaga gtttaatact aataatgaca tagatgggtt
    21121 aaatgctgaa ctctggcttg atatggataa gtatgggaga gcctatgaga ttatctatcg
    21181 agattcagat gatacagatt acgttgattt ggctaatgta tttgaaacgt ttgttgtata
    21241 tgatactaca gtaaaacgag agcctatttt ggctgtacgg tatcctaaga caagattcaa
    21301 caaggatgct gataaacagt acattcaacc aatcgtatac acaaaagaaa aaagtatcac
    21361 ttatgatgag acgacactaa cagcaattga gttaaagaat ccccaggatg aaccgcatga
    21421 atataaagag gtacctatta cagagtattc tcctaatcgt tttcggatgg gcttgtatga
    21481 agatgtacta tctttgattg atctatacga tgcagggcag tctgataccg ccaattatat
    21541 gactgatcta aacgatgctc ttctagttat tagtggtgat attgaagcag caggactatc
    21601 cacagaggac gccatcaagc agaaagaagc gaatatgctt ttgcttgagt ctggaactga
    21661 tgtgaacggt aataaaacaa gtgtgactgc aggatatatt tacaaacaat atgatgtgaa
    21721 cggtgtagaa gcatacaaat acagagtacg caaggatatt cacgaaatat ccatggttcc
    21781 tgatcttact gatgacaatt tttccggagt gcaatcggga gaagcaatga aatataaatt
    21841 atttggattt gaacaaatga cggcaacaaa gcaaaggcta ttcaaaaaag gccttatgcg
    21901 gcgttatcgt cttttattta gcctaaaatc aagtatttct gaaatggata actccgattt
    21961 gaaaggctta cgtgtaatat ttacgcctaa tctacctaaa gccattctgg aagagttgaa
    22021 atctttggtt gatgctggag ctgaactcag tcaagagacg atcttaggac tcgcttcttt
    22081 tgttccagat gtacaggcag agttgaaacg agtaaataaa gaaacgcaaa agcagattgg
    22141 catttttgat tcagatggtg aagaagtaat taacaacaaa aaagatgaaa caggggggtg
    22201 attaaatgaa ctcccaagaa tattggatca aacgggaaaa ggaatggcaa aagcaacaaa
    22261 ttaaagatga taaaaagcgc atggcagaaa ttaaaagtcg catgcaatac gcacaagatg
    22321 cgatacaaaa agaaatagac gcgcagtggg acagtttctc caatggccag aaaatcactc
    22381 gtagcgaagc gatgaagcgt gctagtgaaa tggatgtcaa agcattcgct cgcaaagcaa
    22441 agaagtatgt caaagagaaa gatttttctc ctacagcaaa ccaagaatta aagctataca
    22501 atcttacgat gcgtgtaaat agattagagc tcttaaaagc taatatcggg cttgaattga
    22561 tttcactgtt taatgaattg gataagtact tttcgaatga attaacaaaa gctggtttag
    22621 ctgaattgaa gagacaagcc ggtattttag aaatgactat tgcttcaagt ggatatgcaa
    22681 agctgataga actagtaata aacagctcct ttttgagtga tgacgtgtct tttagtgatc
    22741 gcttatggat gtatcaatct gaattgaaat cagaattaga taggttgtta gtcagaagta
    22801 taacgatggg gaaaaatccc aagcaacttg catctaaatt ggcagaatat ttaacagctg
    22861 aaggacgaga aaacactaag ttcaacactc aacgtttgat ggtgactgaa acgactagag
    22921 ttcaggtagg gattcaagaa cgaagttata gagatgcagg cattacccag tacatctata
    22981 tagcagaacc aacggcgtgc aaactatgta taccgttaaa taatcaagtt tttgatgttg
    23041 ccgatatgca gccaggaagt aacgctccta atatgcatcc attttgtcga tgcagtacag
    23101 caccttatat agaacgaata tcaagccgtt aacacaaatt aacggctttt tattgtgcct
    23161 tcttacagct tacaggcgtt aaagagaaag ctattttcgg ctgaccggcg taactggtca
    23221 aatttatcgg gtagcggcgt aaccgtggag gattaatcat gaaaaaacgt ttatttatgc
    23281 caatgaactt acaatttttt tctgaaccag gagatggtgg atctggtgat gagggacaac
    23341 aaggaaacct accagctggc tcacaagaga caccgcccga agcaaaagaa gaaaacaata
    23401 ctggcaaaac attttctcgt gatgaagtag cgaaaatgat cgctgctgag acgaataaag
    23461 caaaagcagc gtgggaaaaa gaactagcag caaaaaaaga agaagctaaa aagctggcaa
    23521 aaatgaatgc ggaagaaaaa ctacagcatg agttggagca aaaagaagct gaaatcgctg
    23581 aattaaagcg tggacaggca ctatctgaaa tgacgaaaga agcttctaaa atgctgacag
    23641 atgcaaattt accacacgat gatgatttac ttggtctgat tgtttctgat gatgcagatg
    23701 ccacaaaaca agctgtagca gtcatcacta actttgcttc tttgattaag agagaaaacg
    23761 caagacaaac accaccaaat gaaggtggac aatttacagc atcgaaaaat actaaagaaa
    23821 cagtggctaa actagctgct aaaaatcgaa ttatcaa
//
LOCUS       DAIGWC010000040        23827 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.040, whole genome shotgun sequence.
ACCESSION   DAIGWC010000040 DAIGWC010000000
VERSION     DAIGWC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.040"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(53..787)
                     /locus_tag="NOB74_001658"
     CDS             complement(53..787)
                     /locus_tag="NOB74_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCI1220848.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="NOB74_001659"
     CDS             1114..1524
                     /locus_tag="NOB74_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HCI1220849.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="NOB74_001660"
     CDS             1517..2218
                     /locus_tag="NOB74_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HCI1220850.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="NOB74_001661"
     CDS             2218..3804
                     /locus_tag="NOB74_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220851.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="NOB74_001662"
     CDS             3823..4044
                     /locus_tag="NOB74_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HCI1220852.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="NOB74_001663"
     CDS             4041..4802
                     /locus_tag="NOB74_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HCI1220853.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="NOB74_001664"
     CDS             5182..5691
                     /locus_tag="NOB74_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCI1220854.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="NOB74_001665"
     CDS             complement(5766..6305)
                     /locus_tag="NOB74_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HCI1220855.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="NOB74_001666"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="NOB74_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HCI1220856.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="NOB74_001667"
     CDS             7318..8169
                     /locus_tag="NOB74_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCI1220857.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="NOB74_001668"
     CDS             8197..8832
                     /locus_tag="NOB74_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HCI1220858.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="NOB74_001669"
     CDS             8852..9625
                     /locus_tag="NOB74_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1220859.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="NOB74_001670"
     CDS             10033..10830
                     /locus_tag="NOB74_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HCI1220860.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="NOB74_001671"
     CDS             10808..11221
                     /locus_tag="NOB74_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI1220861.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="NOB74_001672"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="NOB74_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCI1220862.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="NOB74_001673"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="NOB74_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HCI1220863.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="NOB74_001674"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="NOB74_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCI1220864.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="NOB74_001675"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="NOB74_001675"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HCI1220865.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="NOB74_001676"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="NOB74_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HCI1220866.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="NOB74_001677"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="NOB74_001677"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HCI1220867.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="NOB74_001678"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="NOB74_001678"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HCI1220868.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="NOB74_001679"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="NOB74_001679"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HCI1220869.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="NOB74_001680"
     CDS             21905..22483
                     /locus_tag="NOB74_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1220870.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="NOB74_001681"
     CDS             22535..23017
                     /locus_tag="NOB74_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HCI1220871.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="NOB74_001682"
     CDS             23134..23508
                     /locus_tag="NOB74_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220872.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7780 a         4286 c         5116 g         6645 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcgtg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtt
//
LOCUS       DAIGWC010000041        23034 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.041, whole genome shotgun sequence.
ACCESSION   DAIGWC010000041 DAIGWC010000000
VERSION     DAIGWC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.041"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..2564)
                     /locus_tag="NOB74_001683"
     CDS             complement(<1..2564)
                     /locus_tag="NOB74_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220873.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIP"
     gene            complement(2786..3670)
                     /locus_tag="NOB74_001684"
     CDS             complement(2786..3670)
                     /locus_tag="NOB74_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCI1220874.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(3765..4202)
                     /locus_tag="NOB74_001685"
     CDS             complement(3765..4202)
                     /locus_tag="NOB74_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220875.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(4419..5330)
                     /locus_tag="NOB74_001686"
     CDS             complement(4419..5330)
                     /locus_tag="NOB74_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCI1220876.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(5707..6345)
                     /locus_tag="NOB74_001687"
     CDS             complement(5707..6345)
                     /locus_tag="NOB74_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220877.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(6349..7119)
                     /locus_tag="NOB74_001688"
     CDS             complement(6349..7119)
                     /locus_tag="NOB74_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HCI1220878.1"
                     /translation="MIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQE
                     ISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLK
                     IKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFS
                     FFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIER
                     EPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            complement(7537..7953)
                     /locus_tag="NOB74_001689"
     CDS             complement(7537..7953)
                     /locus_tag="NOB74_001689"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220879.1"
                     /translation="MMTREKEAYERFILLFVERFNQAFHTDYATNIFEDFENSYSYSV
                     ISSTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNGFSLHQVLWCLLGKKKI
                     IITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGI"
     gene            complement(8004..8385)
                     /locus_tag="NOB74_001690"
                     /pseudo
     CDS             complement(8004..8385)
                     /locus_tag="NOB74_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8511..9176
                     /locus_tag="NOB74_001691"
     CDS             8511..9176
                     /locus_tag="NOB74_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220880.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="NOB74_001692"
     CDS             complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="NOB74_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HCI1220881.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(11724..14246)
                     /gene="pglZ"
                     /locus_tag="NOB74_001693"
     CDS             complement(11724..14246)
                     /gene="pglZ"
                     /locus_tag="NOB74_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HCI1220882.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(14362..17994)
                     /gene="pglX"
                     /locus_tag="NOB74_001694"
     CDS             complement(14362..17994)
                     /gene="pglX"
                     /locus_tag="NOB74_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HCI1220883.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            complement(18058..21729)
                     /gene="brxC"
                     /locus_tag="NOB74_001695"
     CDS             complement(18058..21729)
                     /gene="brxC"
                     /locus_tag="NOB74_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HCI1220884.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(21754..22329)
                     /locus_tag="NOB74_001696"
     CDS             complement(21754..22329)
                     /locus_tag="NOB74_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HCI1220885.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(22329..22928)
                     /locus_tag="NOB74_001697"
     CDS             complement(22329..22928)
                     /locus_tag="NOB74_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HCI1220886.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         6993 a         4531 c         3344 g         8166 t
ORIGIN      
        1 gggatagaaa gaacaaattt acctgtatca tcaatagttg tttcggacaa aacagcttga
       61 ttttttttca atgaaaccaa agctcctgct tcgcctgtac ctgtgattga gcgagaagct
      121 gcattgatca atgtggtact taatttagca ggctcaggag gaatcacatc gactgtcgtt
      181 ttggcagagt ccagttctgt cacttcttgg ccgcctctta cttttttagc agcaactatt
      241 tgcacttgat cccccgttgt tagtctttct tcgttgggta cttgaacctc aaacaaaccg
      301 ccttgttcgc cttctcccca cggattatat cctgtccctt cattttcatc tgtttgtcct
      361 tgtgtgagag cagtaatttc tacaggtgat ttcgtcgtat ctgcataagt aatacgtaaa
      421 gtcacttcta cttcgcctgt ccaagcatct cttggctttg cctcgacacc ttcgggaaca
      481 acgacatgcc catagatttt tttatctgca ttcgttggta ctcttaagga ttcaatcatc
      541 ggaagctggt tattggcact gattcgatta taatttttca ttccggcacc tgtctgagca
      601 aattcatttg ttaaacctgc actagggctt gatacaaaat tacctaagtc ggttccattg
      661 atcgataagt ctgtcatatc agaaaaataa tccggatctt tttcaaagtt atcgaacgtt
      721 actcctgcct ttcgccataa agcaatttct gaatgagcga tcttcaaaga agaatcgcca
      781 tttccttgaa atacccagcc acctatgcca ttagtctcgc ttccgatccg tttgttttgg
      841 aaatcgaaat aggtaggaga ttctaagtct acattcaaca catccccact gatgatgcca
      901 gtcttatctt ccccagtttt cccgaccatg actaaataag ttttttcgcc agccataaag
      961 ttcaaatcaa tatctccagt tgtatctacg gtagctccgg aatctgcgcg tatatcgata
     1021 tttgattttt ctccagtaac cgtaaaatca gctgaccctg gactttctag aaaaccagaa
     1081 gcgtcataaa attggatcgc ttggtttcct tgattgagtc tgttcacata agatttgcca
     1141 tcccctgcat ttcttacctt caatgagcct ccattagtta ctgttagttt ttgcgtaccg
     1201 ttctcaaaac gaactgcgct agaacgacca ctttgcttat caatatcgat gactgatccg
     1261 gctccttcta cgatcaaaga aagtcctttc cctacaaaac gcatcccatt gtttccaggt
     1321 tggtcgccat ctccagccat tttgaccgag atttgtccac cacttgatac atggatttga
     1381 ctagaatctc cttgcaggcg aaatccgcca gtagtcgctg tattgattgt gattttccca
     1441 tcattcgaca cagcgactct tgatcctgag cctctcattt ggataattcc gcgattgttg
     1501 tcgttggtaa tattgatctt tgtatttacc gaaaattcac ttcctgagcc actgacttta
     1561 aatgtgacat tcccgggtag cgtatcgaca gcctctcctt catcgctgac gccatctgcc
     1621 cgatcatagt caagagagac ctttgaacca ctcaagatat ggagtcctgg tgctgttttt
     1681 ccactgcccg tctcatcacc tgaatctaga aaaccataga attttcctag atatggtcca
     1741 taaagctgac taccattgat tacatttagc tgatagcttc tacaaaaata agctttaccc
     1801 ggagcggcat tcatcccttc tttcactggt tggacatcca atacaccgga aacaccatct
     1861 aatgtgacag ttgcacgagg ggcgtaaatc aggcctaatt tagaaccatc atataagtca
     1921 agtgtcccgg taaattttat ttctcccgta aaatgatatc tgtttcccca aaaatcggac
     1981 atataagcaa tgataatggc atttccatcg atatttggta tcaacccacc tggatgagct
     2041 gccgttcctt taaaattctg aaactcgatc gactgaggtg tctcattgat atagatgtga
     2101 tgtgtgccga aattatgagc aagtccgcca aaatcgataa cgatatctcg cttgatctcc
     2161 aattccctgt ctaaagtcaa aggctgagtt aaacgaatct tagctactga ttcgtctgcg
     2221 agaagctgcg tcagttcttc tgttgtggca gcttcgctgt acccatccgc tgaaacaact
     2281 ctaacctgta cctcttcact gctatcagac gtttgttcag ctacttctga ggtctcactt
     2341 gtcttatttt cttcttgcct tgtattagaa gtaggcgcct cactttggga ttctgtagtt
     2401 tcagaagtaa ttgattcttc tgaaaaagta gtcttgtcaa aactttgatt ctctgattgc
     2461 gttgattcgc ttgttttctc tacatcggca aaaacggatg tcaccatcaa gagagggaag
     2521 acaaacaaaa tcgacgcaat cagctttttt acatattgat tcattctcca ccatcctctc
     2581 tgacgttttg acaattttat tttaacgttt taatttattt gtaattgtac tttcatattt
     2641 aaaatatgta tttttatggc aaatttttct gttaggtgaa aatttctttt ttgtacaaaa
     2701 aaaggctgtg acaaaagtct tgtcacagtc ccttattccg aacaaccgat gtcctcctga
     2761 caactcttcg gtcacaacct ccattttaac aataaacctg taaatgtgag ggtaacactt
     2821 tgattgtcac aggtaattta tccccttcat ctccatcaac attcgtcgtc aattcttcct
     2881 catcagctaa tgacacaact aattgctcac aagtaagata ggctagattt ttcgtagatt
     2941 catctactcc ttttaatagg tctggcaatg ttttaagcgt atcgatcaaa gaagaatctt
     3001 ttaaataaac caaatggagc ttaccatcat ccacttttgc atttggaagt aatgtttcaa
     3061 aaccgcctac tgagttagtt agtcctatca gcaagatact gctctcaatt tcttccttct
     3121 ttccatcaac ttctacgtga aacgagtagg attgtgtgga agctaactgt ttgattcctg
     3181 acatgaaata agctagtttt ccaaatttcg tcttcttctc cgcatctaca tcattgattg
     3241 cttcagggat agagccaatt gcgacgacat tcataaaata gtcgtcattt atttttccaa
     3301 tatccaatgg cttgactgat tcaatcgaaa aatgattgat cgcttcctca ggttctagcg
     3361 gtatccctaa tgctcgagcc aagtcattca ccgtacccaa tgggaaaaat ccgaaatttg
     3421 gccgatgttc ttgttcagcg attccactga ttccttcgtt gactgttcca tctccgccca
     3481 tgacaaacac actatgatac ccttccgtag ccgcttcgcg agtaaagttt tttgcatccc
     3541 ctgctttttt tgtatgcaag acgaccactt catcaaacac cgattccaat tttgctatcg
     3601 ctaattgctc aaattccttt gcttgttcac cgcctgaact ggggtttacc actaataaaa
     3661 cttttttcat cactttcttt cccttctgat tgatttcttt aatataacga tagcataaag
     3721 aaaaaaatta ggctgtgatg aagtactgtt catgaaacat tcatttattt tttgacaaga
     3781 taaaataccc atactatgaa actgaggaaa attaaaacaa tgatatagga aataaaagaa
     3841 aatgataggc attgtatacc taataaagta aaaatcttag gtggcagata aaaacacaaa
     3901 aatagcaaga gaatgtaata gcgtttcttc cactttttgt tatcagacct tatagcgatc
     3961 agaggaatac caaatgcata actgaaaaac tcttgatgta ctgttaatat gtcacgacct
     4021 tgaataataa atgcaacaat ccccgctata attagtgtgc ctaataccaa aacggaaaat
     4081 tgatgaatat attttatata caaatgatcc attgtacttc ctgccttttt atttgtgaga
     4141 aaaacaaatc cgtatacgtg aataacttct agaaataaaa gaaatttgca aaaccactcc
     4201 atttatctac ttctacgtgc attttttaat atcgttttct ttatttaaga ttatacagaa
     4261 aaatatctag ggtggctgga ttctaagtaa aaaaaatttt taaaataaaa agaactaaat
     4321 caagtaataa ttaaactact gttgatttag ttctaataaa aagatttaga tgaacagttt
     4381 tattgattta aatagttcat attttttatt tataccgctt atttactact tgctgtacta
     4441 gaatctgaag tgaatgtact caaaacattt tcaaagtctt tgtctttgat ttttacatta
     4501 gcgtctttca atacttcgcc aattacttta ttctggaagg tactgtcact taattttgtg
     4561 tctgttgcaa tttctttcaa ttcttttttg tatttatcca tgtcgttgcc tttgttttgg
     4621 tttttcacca ttttaaccac ataatattcc gtagtataag ttgaagcatt ggtagaagtg
     4681 atcacatcag aaacttgacc atctttcaac ttaaaggctg cttctttgac ttctgccgga
     4741 accgttgtag tagtggaatc aaatttcact tttccgccat cttcttttgt cgtagtatca
     4801 gttgacttgt ctttggctaa tttagagaaa tcgtctccct tatcagcagc tttcttcaca
     4861 tcttttgcat catcttcact tgctacttgg ataatttgag cttccacttc tggatggaaa
     4921 gattcccaag ccgtttttaa atcttcatcg gtcaatttga tatgtttctt tagaccttct
     4981 tgaaaggcta gactttgttt gatactgtct ttgaatgttt gttctgtgta acctgcagat
     5041 ttcaattgtg aatcaaatga atcacccaat tgtttctttg tttgatcata ttgggaatcg
     5101 atttctttgg ttgatacgtc atctccatat ttatcttcaa atacttgata aacgatcaac
     5161 tgttgcacag cggaatctgc tccttgcatt tttttcaagc tatccattac ttcttgttcg
     5221 ctgattgtac cgcctttata actaacggct gttttttcac cggcattcgt acagcctgac
     5281 aataagccag tgcctagtac gatggcaagt gctaaaaatc tttttttcat ttatcaattc
     5341 tcctactttt cgttttttgc gaattgctaa aaacaaaggt gttcaagatg aaaatcatca
     5401 agaacacctt tactaatctg ctcgatacgt cctgaataga tataaggcta cacaatccag
     5461 aaagttcgct cagcagaata aatgtcaagt agcacatcac accttaatat actacttctt
     5521 ttgttaccgt ttttcaagtc tatcttgcgt tccgtattta acgtaactaa ttcttagaac
     5581 aaatgttatc gattttgttt ttcttcttcc gctgttggga tattcaaatc agacactttt
     5641 atgttcgatt ttccagacat ttttttgttg tttttattag aaaaagtttg ttttttcatt
     5701 tgttttctaa agcatgatct tcttgtttcc tattttggtc agatatggat catgcgtgac
     5761 cacgataact aacgtacctt gggaagcctg ttgcgataag atttcaacga cttgctcctt
     5821 atttcgttta tctaatgatc cagttggttc atcggctaaa atgattttgc tattcttcaa
     5881 taagactctc gcacaggcga ttctttgctt ctcaccacca gataatgtgt agataggcgt
     5941 acttagcttc ttgtttatat ttactttttt caatgcctca tactttgctg ttcgcttatc
     6001 tgaaacattt aaattcgaaa acttcaatcc aatatctaaa ttaaaatcga ttgtttcata
     6061 ttcaatcaac ccaaaatctt gaaaaagaaa agagagggca tttcttttta tcaagcgctt
     6121 ctctcttcca gttaaatgtt ttgtttcttg attaaataaa taaaattgcc ctgaactgaa
     6181 ttgatcattc aatcctaata tattcaataa agtacttttc cctgctccgc tctctccaac
     6241 tacagtcaca aaatccccag catccgcagt gaaacgatcc aaatgaagaa tcgttttgtt
     6301 tcgaatgatt tttttcgcac cttttatcac tatcaacggc tccaattgtt aacctccatt
     6361 catcagcaat aactgacttt tcttttctgt agacaaaata aaaacaactg aaagaataaa
     6421 atcaatgaag ctaaagaaaa aaatattaaa aagatattta ggctctcttt ctataagaaa
     6481 aaggaagatt acacttgtcg ttccccattt gatgaggttc atcatgaaga aatctttata
     6541 cgtttcaaag agcgaataac cacttgaacg aaagatagcg attttccgac aattgtagac
     6601 aaaatatatg cataacatga catagctcaa caagaagaaa gaaaagaaag tgagtaaaaa
     6661 tatctgtatc aagtaatgaa atgatctgct taacactttg acagctatct cttcagtctg
     6721 agtatacgga aatgataact gcaagttatc acgtaactga ctttcttcaa tcagctcaaa
     6781 taacctttct ttcgacaaag agcctatctt gatctttaac ggtggataga tttctccgct
     6841 gagaatattt ctttcccaat acgtactgtt tttcaatgtc agtatttcaa caaccggata
     6901 atgttcgatc caggggatag aaggaataaa tgtataaatg ggttgattgt tttttataaa
     6961 tagaaatttc ggttcttttt cactgatttc ttgataatat tctgttattt gcgccaggtc
     7021 attttttaaa tctgtatgtc tatatcgttc agggatcaat ataacagggt gcgtttcttt
     7081 ttcggttatt tggatcaacc ttccagagac atcaatcaaa ggaaatttct taagataatt
     7141 cagatttatt tttatccctc tgccaaactg ttcattttct tcattcaagt aatctgatac
     7201 attgactaat atacttccgt ttttattcaa agtttcatat aattcctgat cggctgctga
     7261 tgcaaaacga ttggaataaa taaaatccac gtggtttttc ccgatggtta ctggataaaa
     7321 tacatgatag tcctcaccag cgatttcttt tggtgtttca tgggaaacag ctaactgtga
     7381 agaagaaaaa acgatagttg ctaattcgac attggcaacg gtcaaaagaa gagaaaacaa
     7441 caatccaaat gtaaaaagaa tgtattggat atagttgaac gcttctctta acgaagcgat
     7501 tttttcaact aataaaagag aaatcaaaga gataccctat attccgctga acaagaaaac
     7561 gtacatctgg aacaaataaa gaaattgctc cttataatac ataaaaataa aaccaccaat
     7621 gattcctgca attatgaatg taataatgat tttctttttc cccaataaac accacaatac
     7681 ttgatgtaat gaaaagccat tattcaacaa taaactgatt tctttattca tcaataagaa
     7741 aaaggatgat aacaaaagga ataaaagaat caatccaata gttaaataca ctcgataatt
     7801 atatacgtct gtacttgaaa taaccgaata cgaatagcta ttttcaaagt cttcaaaaat
     7861 attagtggca taatcagtgt gaaatgcttg attgaatcgt tccacaaata gtaaaatgaa
     7921 ccgttcatag gcttcttttt ctctcgtcat caagaaaaat tcaccttcaa aatcttttat
     7981 tttgatcgat tcttcaatgg acgttacgcg aaaggaggta ttagaatagg gtaccttctc
     8041 gtgagaagat ttgacatccc cttgataata caatgtcatt tcaagctttg gctgtatctt
     8101 gaagttccaa gatgtatcta cttcattgga ttcatttact gtttttttca tataagaaag
     8161 ctcagtttct gatgagacat tttcaaatac catgattagc tgctcatatt cttcttgccc
     8221 aataaaatgt tgtggcaatc gaatcggagt ataagtatct gtttgatgga aaaattcatt
     8281 tgtccgatag agtacctgtt tatttataat aaccaaggca aaaccactca tgataccggt
     8341 cactatgatt gtgagtaaaa ctgtgaactt ttttttgatt atcaccactc tcccttactt
     8401 aaatgattct ttgataaaat cataccgttt ttcatcaaaa aaacgtatct atcaaatgta
     8461 taggtcatgt agaataaatc tatatactgt agaatcgaaa ggagaagaag atgaacatcg
     8521 gagaaaaaat acgaacttac cgcagaaatt gtaagcttac gcaaaaagaa ttaggcgaaa
     8581 aaatcggtgt ttccgataaa acaatctcta gttgggaaaa ttctcgtaca atgccagacc
     8641 ttgaaatgct gtcactttta catcagactt taggtctgcc gattgatttt ccttctattg
     8701 aatcagctac cgaatcaata gaaccaacat tgccggatga acctcttgtt atcaagaaat
     8761 cttattcatc aaaacaaccc ttctcactca aaaagacact atctttcttt ctgctcgtct
     8821 tttgtttggt ctatcttttt cttatcaatt atcaatataa aaatgaaacg gttgatcgat
     8881 tcaatccttt tttgaaacca caaatcggct ataccacact ccctgtagga tacgtggaaa
     8941 attccatcga acattgggta tgtaatgata tctttgttca tggtacatgg ctgtcttttc
     9001 acgctggaga ggtagaaaaa ggtaagaatc atgctgtaat caaacacaaa ggaaaacacg
     9061 tcatgaacgt tcgcctgctc acttgggaag ccattccctc agattaccaa gaaatcctca
     9121 tccaagacta tgacgatgcc ttaaaaagaa gccctcagga gccagatagg cattaagtag
     9181 gagatgaacg tagagataga aaaaatcaat gcacatgatc ttatcaaaaa aaaacagggg
     9241 tacaaattaa ttgaaaaagc tttgagatga aagttcctaa ataaaaaagt tcagaatgat
     9301 aggtaaaaaa atgactaact attctagtat taggctattt gtattattct tctgttattt
     9361 ttatatcaaa aaatccagaa ataactaaat ataggtattt ctggcttata gtataatatt
     9421 tacgccacag cccccaatga ttctttttgg aatcatgatc aaggacggac atacacaaaa
     9481 atattttgcc cattcgatcc gaatagatta acgactaatc tagtaagtaa tatagattgg
     9541 tacgtagtca aaccagcaaa tggaaaagtt gtctattcca ccccaagggc tttaaagaca
     9601 gcatcttccg gcgtttgata aaaaatcaaa ttaaaggtac ccattaattc tgggggtaca
     9661 gttccaatat cagcagcgct tatcataggt acaagtactt ttttcgctcc ggcatctttt
     9721 gctacttgta aacagttagc taaattatct accttaatca tagaaccacc aattgtaata
     9781 tcccctaaaa taactaaact tggtaataca ggtttattta aggaaactga gcataaagct
     9841 attatagttg ataacgataa tgtttttgtc ataccaatgc cattcatatc ttgaacatga
     9901 acgacaaaat cttttgtcgt caaactaata gactgactaa cacttccata attagctctt
     9961 aaatatcggt atgccgaatc catcgcttct cttgctccag catctgaatt gatcccagta
    10021 cgttcaaact ttccatttcc cgaagtcatt tgcgtttcca atttataggt acctaattgc
    10081 ccagttttgc cataagatac cgtgtacaaa tgccctggct tccctaaccc ttctggaatc
    10141 aaagttcctc caccttgttc aggaacagaa acatactctt ctcgctcttc ttctaaatca
    10201 atgtatgaaa aattgacatc ataaaattcc attccaccaa ttttctttaa ttgttctttt
    10261 acacgacgac gcatttcaag agcaaatctt agtatttctt cgacatcact tttttcaaat
    10321 ctaccatcag gatacaacag tttcatcatc ccagatacaa tccgacgaac tgcaatcgta
    10381 tcccgctgat ttaattgaga accaagtttg aaatatttat caaaactatc gccaaaacta
    10441 acttttcgaa gctcacgcat gacttcagaa aaataatctg taatgaagcc atagtcattt
    10501 gtaaaaaaat ctggtcgata tttaggaatt tcccaacctg gtaaataaca atgcatccga
    10561 tccaaaaagg ctgaatccgt ccccataacc tccggaaatg gctcaaataa attcgaagtt
    10621 ttcaatatta catcaacgct ttgattaata tttcctacaa aagccattga tgctgaagca
    10681 ttcttttctt ctttgcctct agcaaaagat cctgaagcca tgtaatcttt catgatttga
    10741 acgccatcat tatccttaaa tttaatccca gcaacttcgt caaaagcaac acagtcccac
    10801 atacctacaa gtcccattgt acgactagcc atattataga aaaggtttgc tactgttgtt
    10861 tgtccacctg aaacaaggat tgagtttggt gaaatttctt tatatacatg cgatttacct
    10921 gtaccacgtg gtcctagttc acagagatta aaattatttt caattaatgg aataagtctt
    10981 gctaaatgaa gccattttac ccttttatta aattgtgtag gttccatacc aatggaccgt
    11041 agaagtaagt caatccattc atttgtagta aactccttgc gagccatctt gtaagcctca
    11101 atgtctaaac caggcatttg gattggatca accttttttg caataaaagg gctattccaa
    11161 cgatcattct catcatacca atattccatc gaaacaatac accagatccc cccacctaat
    11221 aatcgatcaa attttttcgg atactcttca ctaatttgaa cattttttaa tcccaggtta
    11281 gagaattctg cttcataaca atctttcttt tcatttaaat gtacagttac tttatcaata
    11341 actgtataac cacccaattc acgaattttt gcttttactt tttctgcttc atcaggacgc
    11401 acatagtttc gagcaagaat atttttaaca ttttccacac ctttttcaac caatgtttca
    11461 tccaatgacg aagcatacat accaagtaaa tattccaata cataaacagg tacattcgca
    11521 ccttctttaa ttttctttgt taaatctttt ctgacaatct ttccgggaaa gaattcagat
    11581 aactttaaaa tttcctgttg ttccactaga attcctccat gtgttcagtc attataatag
    11641 caattaaagt atatcatact taaccagtag gcttgataat acaaaagaaa aagtatccac
    11701 aaaaaattgt ggatacctcg tttttatata tcaaaatcaa atgattctgc aaaaggatta
    11761 tctataatga attttattcg ctcggtcaaa tcattttttt gattttttat cactaaataa
    11821 taagtatctt caactgtata tcgacgattt acaaattcaa aaacaaattt agtaaaccgc
    11881 tgatttgcat cttctgtttt tgaatccgca acatagattt cttcatttga gatacgttca
    11941 ccatattcat cttcaaaata aagccagaaa gatgcggggt cataaacatc actaattgca
    12001 tttttttgat agaattctaa cgtggttgat aatcctgtaa ttctgcggtt gctagtcatt
    12061 aattcaattg ctactggttc ctttgcattg ctacctttgg ctaccgtaat ttctagaaca
    12121 gggactagca tttcttgaat agatgaccct ccatgaacgt agctttgtcc cccgccagct
    12181 ttcttaaaaa tacttgaagt aatcgggaca caaatgtttc tagtgtcatc atttcctaaa
    12241 gaatctccca aagagtaatt tttcgtacca attatttcgt attcttcttc actaagaata
    12301 aaacgacgtt ctacacgatc tttttcattt ctagatggat tttcaatctt atctacttct
    12361 tcaacgtggc ttcttttata aataaatcca tgatcagccg taactataaa acgatagata
    12421 ctgccatcat tatgcaagcg attaataagt cgggaaattt cgcttatcgc taaatcacag
    12481 gcctcaaaaa ctcgattttc attcgagtga tcacctgttc tatccacttg atcgtgataa
    12541 atataaatga ctgatttgcc attaaatact tctcgtacct cagccttatt catcttaacc
    12601 acatcatcat aatttaaagc tacagcattt gcatctcgtt gctggagaat cgcatttcga
    12661 ttggataaac cattcgtttt tttcccatca atcagtactt ctgttccttc attgtaagtt
    12721 agttgattgt ttggtaataa ggcggcttta ccgaattcag taactgaagg taatacagaa
    12781 agaaagctag ccatgtttgt tgaatacttc ttttctctaa ctaacttacg ttctaaattc
    12841 atccctaact catatcgaaa agcatctgaa ataataacta cagttttaac agagcgtttc
    12901 attacagctt gattataaaa ttttcgaatg gatggacgat tcttaaattc aaaagtttga
    12961 ttccaaattt gtcctgattg atcaagaaac ttcgaataat ttgcttcaac taatcgatac
    13021 aattggccat atttttgctt ttcttctata tgatcactat tccaaataaa tttccgataa
    13081 tgcgtatcaa cccaatacat ttccttctca tattgagtta gcaaattatc catgttcatc
    13141 ggcaagcaca atctgttttt atccacaaga taataagcat gtttcaataa ttgatactca
    13201 taaatataat ccgatgcgaa atgcattttt tcgcgctgct ttaaactatc aaaaattgtt
    13261 tgtcctgcaa ttttcgttgt agtgtcagaa gcctttaatc gttctgcata aaacattaat
    13321 atttttgcat gaatctcaga aaatacgtct gcttcaatta gatcatcaat ttctatactg
    13381 tctaataatc catcaccatc aatagcctga tatacttttt tagatagctg ttcaaagctt
    13441 tccatgtaac gtgtatcatt cataaactga tccatgaaag taataatgtt tgctttcaaa
    13501 tgtagtattt caaatccttt gaacttcttc ggcatctctt gatcaatttg ataataaaaa
    13561 tagttcaaat aaagacacat cgtcagcttt tccaatgttg gctggctatc cgtaaagcca
    13621 aatttcattt gaataaattc ccaaaattta gctgttaact gatacttatc aagttccctt
    13681 aaaggattct ccctactttc tgtaaagctt tttagaacta cacgcagtaa atcatttaat
    13741 cgaatacttt tcgatttcaa caaaacagcc attatcatta attcaatcgt ttctgattta
    13801 ttaattgtca tatgcgtact aaattcacca aaacttctca tgcgatcctt tgcattaaag
    13861 aaattacgat actgtttaac tgtctgatga aatctaagtg gaatagccaa ttcattcatg
    13921 ataatcgcta agcggtctgc actaaattcc tctgaataat tcaatacact caacaaatga
    13981 ttatcttcat ctttatcatc ccaacgagga aatggcgcat agattaaata gttagtttcg
    14041 ggatcttcat attccaataa acgcttagtt ttaaattgtg cgtccttttc taatcgatag
    14101 atttttgcat tttgaatgac caatgagtca atttcttcaa gaaaatcctg atttgaatca
    14161 aaccaaaaaa tgattttcct acatccataa ttaggaaaac gttgatttaa tttttcttca
    14221 atttgttgcg tatttatatc tgtcatcaat ctcacctaat cgttctcttt ctatacccct
    14281 tatattgaca taatttggat aatttcgcac gcaatttaag aataaaaaag aaagttgtta
    14341 gaaaacaact ttcttagata actatttttt tggttctttg accccttttg caaaaatttg
    14401 gaatttctcg ccggttttag gatcacgctg caacttatca taattgacaa ttacaccatc
    14461 atctaagtct aattcaattc gttttaatgc taagtgaccc aacttctcgt catactcacg
    14521 aacttctttt aattgcttct gaatctttac aatttctttt gtcattgcat ttctttcttt
    14581 tgggttatca cttgttgaaa tttgttgctg acgcaattcg attcgattgt catacgcttt
    14641 ttgtagttcg tgtaggtatt cagtacgtac ttttcctaat tgatctggtg tatagcgatg
    14701 caagtacatt aacgctttaa agccattttg ttttcctgag tccaattgcc aataaattgg
    14761 tcgattggag tatgttttta aatggtcttt gtaaaaatct tgtacgaagt aacgacgaat
    14821 aatttctcga cttgtccctt tgccacctaa agtgtcagcg ataaactgga gattttcttc
    14881 aagggtttct ttaccaaaag taatctcaac gaaatcaatg aaacgattga caatgtcaat
    14941 ttggctatcc ttgaaatact catcatcggt gatgagtaaa acattatcag tatcaggttt
    15001 aaatttttga tagcgggaag gatcccattc gccgccagcg aagatgagac catcttcgtc
    15061 tagggagtaa cgaccgaaga tacaacctat tgaataagaa ataaaatcct taatttccct
    15121 cgccttatca ggtaaccttg cagagatata ttcatcttga acctcttttg ttaattcttt
    15181 ttcaagagaa taatgattaa tgaatatgtc gttcagttcc tcttcattcg attttagagt
    15241 attaaattga ttaaccaact gcctacttag acagttaaat gcctctgaga gatctttttt
    15301 aaacatataa cttaacaaaa tgtttcttct aaactcgtat gacgtttcaa gagcattata
    15361 gtcttttcta gctatatcga tattttcatc cactttttct cttatttttt ttaattttct
    15421 ctcagatgta actttaagaa aaggtagttt tcccattggt ccttcatggt aatccaaggt
    15481 gggagaaata aaagttaaaa agtgattaac taatttagag tttacatagc caaatatttc
    15541 ttcaaagtca gttatatcct ttgagaacag aacagatcct ttagtttcaa aaattgcctg
    15601 attctgcaat ctaaaagata cttgtccaga tgaaagtgtc gaccaagtaa ttcccttttt
    15661 aaaatagtaa ttaagatttt gtggtctaga ttttaacttc ccattttcat taacataatt
    15721 ttttatttca tctccatcat tctcccagtt aaccacgtat tcattgtttc cataccattt
    15781 tctaaaacga ccacctttag ttgtaggaaa ccattttttt ctagactttt tagcgtcctc
    15841 taatgtttta gcatcaaact ttattttgtt aaattctact tcaaaccaat accgcaaaaa
    15901 tttattgtta tttccggttg ccaacccttg ttttgcatct gcaacatcgt tagttaattt
    15961 tccttgagca aaatcagtga ttacgttatc gcttgcccag taagcaatcg gcattcctgg
    16021 gatttttttg aagttgtctt gattagtact ataaaaataa tcgcattcac catgctgatg
    16081 aattgcttct aacgttttaa ttttttgaac ttccattcca cctttaaaat ctgataattt
    16141 tatatagctt ccatcttgtt catttgaatt ttttatcgta aacgtacaaa ttggaacggt
    16201 tgcttcttca aaagctgaat actccatttg aatcaaacta gaaatgtttc tttcattaat
    16261 taaaaatgag cgtaactttt catagctaga aatgaacatc caaacaaatg gcgtcataaa
    16321 ggaagcatat ccattatcaa tcagcatttg gctattcaat ttaataaaca cagaaaatag
    16381 atcttttttg acatcagaat agttatcatt tacatatttt tttaatttct tatccatttt
    16441 attaagataa ggcggattag tgactaccgc tacatattta tcaactagca tttcagccac
    16501 gtcaagaatg tgcaagtatt tttcttgtat ttccttcatc ccataaagaa tatccatatt
    16561 cgtaaattcg ttgaattttg atatatactc tcttactttt cctaagtatt ctttagttat
    16621 tgcctgatta tttttatcga ctaacttaat gattgatcca agttctttcc cattttcaaa
    16681 ttgatcaaaa attaactctt tgtattcatt ccagcgttca ctatacttat cattgttcaa
    16741 ttcactaata cgctcttgat actcgtctgt cactttagga gaatcaataa actctcttaa
    16801 attcggcgat agactttttt tcaaaaaaag acgatcgtat tgacgccctt tcatcataat
    16861 tgcaaaataa gacaattgat acgctctttt atcgatttca agaccatata aattgtattc
    16921 aacgattgca cgtgcagcat cacgctcaga atatcctaac gtaagataaa tttccatcaa
    16981 tacatcgaag gcgtaaacta aaatatgccc agaccccatt gcgttatcga taatttttag
    17041 ttcttctggt tttaaattac ttacagatgt tgcttgttca aaagcatatt tatctggaat
    17101 taagtatttc aacttatttc ttaattcact attgggataa tgatctaacc aatactttcc
    17161 taaactattg tcaaccatat aacgaacgac ccaatctgtg gtaaatagtt gagttgctgc
    17221 cggaatatct tgttttttga caatcccttt ataaatattc accacttgat tatgtggctc
    17281 actattatag tactgataca accacccaat aatctctacc tgtccaccag cttgaacata
    17341 gaaatcatcc tctggaatac ttaaaagatc agcgattaca ccatcttttt taatataaga
    17401 agctgtaaac aaaagttctg tataatcttc tacttcttca aatagctcag gtaagtaatc
    17461 attcaattga ttacagattt ttataaaaat caattgatac agcttgtcca ttgcttctgc
    17521 tgaattatct gttttccaag ttctgacttg ttgctgttca ttactagata attcttcaaa
    17581 gatatcggca tcataaatat ctgtaataat atctggctca attttcccac ttatttcact
    17641 agataataca cgatacgtgt caggtaaata atcatttacc tccataaacc gaatggcaat
    17701 caatcggtta aaccacgtat aagcaacctc ttcgattaac tcttgaaaag cttctgaata
    17761 agaagtgaca gaagcacgtt gttttagttc tgcaatcaat ttgtttcttt gcgctatttc
    17821 ttttccttga attcttattc ctgatttttc gatttcttgt aaattgctat caattttctt
    17881 cacatcttca atttttgatt catcaattcc taaacgtttt gctttagtca ttacttcatc
    17941 aattaatttt ctacgggcat tgaccgcgaa attctttatc gctttcttat ccatttttct
    18001 ttcccttcta tatgtaacct ttgaaaagac aggcaccttt ttatgcctgt cttttcacta
    18061 gaattgaatc gtgatttctg tattttcttg aagttgttcc ttcagttttt gattaatttc
    18121 agctgttaac tcatcaatat ctgctgctga cttaatagtt ttaacatgaa cgttaagtgt
    18181 tctcattggt actgttttct gttgaatagt aggttttact atcgctattt cttcagcttt
    18241 tgctgcagag tctatttcat ctttttcagt ttcacgaatc aagtttgctg cttcaatttg
    18301 tttacgtgct tgttcttctt gacgtctgcg gttttcttca ttatcgaaac gttgattaaa
    18361 gatcaaatac tgttctgcta cgtttaatga taagaaaaca agatcatcta tagtattcgc
    18421 ttgttcaatt tttgctttca gttcttgaaa ttcttggtca actattggta caaattgatc
    18481 cttaaaatct tttccttcta ataatttaaa tgttgcttgt ttttcttccg ttaatttatt
    18541 taatatttcc tgactttcca actctaacag ttgattatat tgttcaataa attcttgaat
    18601 caactcattt agtttcatca tatctgaata aggatcagcc tttttcaaaa tggttttcat
    18661 ctcatgaatc aattgatcaa tttcttggct agaagtttga cgccgacttt tttcgattaa
    18721 tctaatttta tcttgtgcat tctcccagat ttttttctga gtactatttt gcttgtggaa
    18781 atttttaatt ttatcatatg tttcagccca gtcgaataat tcatcgcgat attttttgat
    18841 tgtataaaaa aagtcttcaa catctgacgt ttgaacaatt acttcaagat atttttttat
    18901 ttgctcatat tcataagcac tagggtaggt ataagtgttt tgtaaatcaa aataagagcg
    18961 taaattgtct aattgacctt ttaaatattt cttgaaattt tccattgtat gttcattgtt
    19021 attttcatca acaatattac gactttgaaa cagttctcta ccgatttcgt caaccaattt
    19081 ttttgctttt ggcgaaatca ccgcgcttgg ttcaattttt atcttttcac tttctcgtcg
    19141 tttttgaata atcattacaa tactatttgg atcatccatc cgtgaaattt gtacattgtt
    19201 ataaagtaaa tcaattttac cagacatgaa aagtttagcg atgcaccatt ccacatcaag
    19261 ttctgtgaat ccatacggtt gttttgtttc aaaacgatca cgaattgttt tcatcgtaat
    19321 cgttaggtga tttctctttt gatcattgat aaaattgaaa atttcctgaa ctgcttgctc
    19381 atttgatgga tcttcaataa tttcattttt gctttctttc actaaatata agatatcttc
    19441 tttttcttta ggcgcatcaa tttggtttaa tttatggtat acttcttcag ccattttctg
    19501 aagtgctgat tggaattttg ctttaaagtc ggagcctgtc agttgaattt ctgcaccgtt
    19561 atagaaaaat tttgcagatt tcaacagttc atttaattga tcgttgatac ttgcacttag
    19621 ttcctgtaat tcaccagatt tttccgaacg aatcgcgtca aagttcttta ctacactcga
    19681 ataagtcgtt gttaaataaa gattcattct agcatacatt gctatatcat ctttaaattc
    19741 tttatctgat ggcaattcta cgaataataa gttacgggaa ctcttaagcg caagttctgc
    19801 ctcttgacct gctaaatcag agtatggtga aataaaatta actgtcattt cagcatttcc
    19861 agcttgcttg tatggacgtt gatctaacac ttgtgcataa gtaaacgtat accggttttt
    19921 aaatttattt ccacctgaca tgcctaattt ttcataggca aaactatttc ggtctagaac
    19981 gccgtcaaaa attcgtttag atagttctac gatcaaatca ctatctgtaa tattttgatt
    20041 tttaatctca cgagtaattt cctgttcttc atcagtttgg aaaatataac tatctaagtt
    20101 cttccgcaca aagttttcct taattaaaag gtccaatgct tcttctactc gttttttagt
    20161 ttccaggcgg tcttcgttga tatttcttat catcaagctc gtaatatttt caacatttgg
    20221 tttgatggct tgatcaacat atttaatcat gaataaaatt cgtaagacat ttacgttaaa
    20281 gttatctata tcagttggtc tttgaatatg agaattattt gtagcttgtg taatcactcg
    20341 gctaattgct gtatcaatcc aacgttctaa cgagtaataa aactgatcta aagaaaccaa
    20401 actggttgta tcattttcct tatttcgttc agcggcttct ttaaacattg ctagtaatga
    20461 acgttcacca gacgataagt ttgatccttg atagctgtga ttacgaatct cggttagaat
    20521 ttgccccaat aaattgaatt gatagggaat aaatggataa acttctgcgt aattttcagc
    20581 atcttggaag agctttaatt caggactatc aacaaagagt aatttatttt tcaattctgt
    20641 ttgaacagtt tcaaattgta aggctaaaga atcattggca aactcttttt tcttcaaaat
    20701 acgttcttta attacttcat cggcatttgc tgaagataaa ctcacagttg tggcaaaacg
    20761 atccttgatc ttagaaaaat cattatcaga attgttatca aagtttgtta cgtgatcaat
    20821 cgcttcctga cttgtcacta atacccaagc cttaccttca caaattcgac ccaaatcttc
    20881 cacaacggtt tgtaactgca aagtcaactc acgattaccg ccgatatatt gtccgacctc
    20941 atcgactaga aaggcaatat gatggtctgc ttctttggaa tcaagatagc ttttaactag
    21001 atttgcaaag tcatcaatgc ttattaaata atttcctgat gctttttcta aaaaattatc
    21061 aatagcggct tcactcataa aatcgatttt aagtgccgct tctttgatat catcttggat
    21121 ccaatcaaac tcatggcgct cttcttgcca ttttgcccca ttaatctctt caaaagcagc
    21181 tttgaatgca tcaaactttt cttctttaat taaccgacgt tcaaaatctg ctagatgtgg
    21241 aatcgtgctt aatccttgca tttcgttaaa tacctttaaa aaaacattca cgattccgtt
    21301 tttgtctttt ttaccacctg catcactttt tgaatcaata ttaaacagaa taacatctgt
    21361 atttatttgt gagcaccgtt ccatcgttgc caaagtcagt ggatctttga ttttcccatc
    21421 ttctttgaag taatcaatgg ctttcttgtc atttatttct cgatttgcga gcaagtaaga
    21481 aataattttt aagaaatgag atttacctga accaaagaac ccctgaatcc aaacacccat
    21541 tttatctgtt ggtgtattga tactccgttg gtaggcatca aaaattgttt taaagtgttt
    21601 ttgtagttct ttcgtaacca cgtattcttc taattcttgt tgaacatttt catcctttgc
    21661 ttgaccgacc ttaataactc cttgaatatt tcggtcaatt ggttttgcaa aaatatcttt
    21721 aattagcatt taatctccta ccttccatcc caactaaatt ctaaatgctc gataataatt
    21781 atcatcttta ttggtattaa gaattgtcaa acttaattca tcatattccc ctggatacat
    21841 catcacaact ggtacgcgat caaatacctg atgcatttta tttaaaatag agtgcgctct
    21901 aattaatgga tataattcgc caattcctgt caggaacaca actgattttt ctggtgtatg
    21961 ggcatccaca tattcaaaaa atacattttc ttcctcaggt aaatccattt tcaataaacg
    22021 accaatgctt tccactaatt tttgtaaacc acgtcgttct tccatcttaa tcgctttttc
    22081 agtgaaaccg cgtttttcta gatactctaa cataatcaca tagagattat aaactttcac
    22141 ttcataatta tcaccaacag atgttccaga tatatcatta atataatctc ttacaattaa
    22201 ctcgtctttc ggatcgtagt caaagatata atagcctact tcattaccta aaccacgatt
    22261 caataaaaaa tcttcttttt gaattacttc attcaacttt tccaaatgct cttgaatcga
    22321 taatgacatt ataaaattcc tcccagtgct agtacaatat ctttacgatt cttgtcaact
    22381 aaccattgaa tcaatcgttt atctaataat atcggagtca ttcgtccata ttctttttcc
    22441 cctctgacta atcctgtttc aattagattc gtttgataag cggcaataag ccgtttaatc
    22501 gtataatctt tccattttga aatatcttct gaacttctcc gcttctctgt aaaaaaagaa
    22561 cggtaatcaa ctggtgttaa ttgcaaattt cctttacgta gattttcagc atatacctca
    22621 gtcataaatt cattaaaaag atcatcaatc ataaggatgg aaatcaaatt cactaacttt
    22681 tgattatcta tatttaactg attgaaaagt tgcaatccag cttcatccag ttgactaact
    22741 ctccttttca cgttctgata gatttctttt tgacggttac tgctcactgc aaaaaaaata
    22801 ttttcatgtt catttttctc tttaatttct atatctgtat atccttctag tcgtaattga
    22861 atatataact tgaactctga aaaccaaaag cgtttagaaa ctagaccagc agaatatttt
    22921 ttattcaata gattgcctcc taatcatcta taattcaata agtaaacaag tgttttttgc
    22981 tcatcgttag cattcatttt ttagtatcta ctatacaata catatttatt atag
//
LOCUS       DAIGWC010000042        22957 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.042, whole genome shotgun sequence.
ACCESSION   DAIGWC010000042 DAIGWC010000000
VERSION     DAIGWC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22957
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.042"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..132)
                     /locus_tag="NOB74_001698"
     CDS             complement(<1..132)
                     /locus_tag="NOB74_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI1220887.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
     gene            542..841
                     /locus_tag="NOB74_001699"
     CDS             542..841
                     /locus_tag="NOB74_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1220888.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            914..2275
                     /locus_tag="NOB74_001700"
     CDS             914..2275
                     /locus_tag="NOB74_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCI1220889.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            2297..2557
                     /locus_tag="NOB74_001701"
     CDS             2297..2557
                     /locus_tag="NOB74_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220890.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2571..3323
                     /locus_tag="NOB74_001702"
     CDS             2571..3323
                     /locus_tag="NOB74_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HCI1220891.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(3417..4022)
                     /locus_tag="NOB74_001703"
     CDS             complement(3417..4022)
                     /locus_tag="NOB74_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1220892.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(4075..5049)
                     /locus_tag="NOB74_001704"
     CDS             complement(4075..5049)
                     /locus_tag="NOB74_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HCI1220893.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(5427..6146)
                     /locus_tag="NOB74_001705"
     CDS             complement(5427..6146)
                     /locus_tag="NOB74_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1220894.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(6273..7544)
                     /gene="celB"
                     /locus_tag="NOB74_001706"
     CDS             complement(6273..7544)
                     /gene="celB"
                     /locus_tag="NOB74_001706"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCI1220895.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7697..9094
                     /locus_tag="NOB74_001707"
     CDS             7697..9094
                     /locus_tag="NOB74_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1220896.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            9175..9615
                     /locus_tag="NOB74_001708"
     CDS             9175..9615
                     /locus_tag="NOB74_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI1220897.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9763..10089
                     /locus_tag="NOB74_001709"
     CDS             9763..10089
                     /locus_tag="NOB74_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI1220898.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            10090..10839
                     /locus_tag="NOB74_001710"
     CDS             10090..10839
                     /locus_tag="NOB74_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220899.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10919..11374)
                     /locus_tag="NOB74_001711"
     CDS             complement(10919..11374)
                     /locus_tag="NOB74_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCI1220900.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11801..12076)
                     /locus_tag="NOB74_001712"
     CDS             complement(11801..12076)
                     /locus_tag="NOB74_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220901.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            12370..13185
                     /gene="thiD"
                     /locus_tag="NOB74_001713"
     CDS             12370..13185
                     /gene="thiD"
                     /locus_tag="NOB74_001713"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HCI1220902.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKGLQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(13514..14965)
                     /gene="cls"
                     /locus_tag="NOB74_001714"
     CDS             complement(13514..14965)
                     /gene="cls"
                     /locus_tag="NOB74_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCI1220903.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            15306..17972
                     /locus_tag="NOB74_001715"
     CDS             15306..17972
                     /locus_tag="NOB74_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI1220904.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            18336..19088
                     /locus_tag="NOB74_001716"
     CDS             18336..19088
                     /locus_tag="NOB74_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1220905.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(19110..20264)
                     /locus_tag="NOB74_001717"
     CDS             complement(19110..20264)
                     /locus_tag="NOB74_001717"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HCI1220906.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            20449..22890
                     /locus_tag="NOB74_001718"
     CDS             20449..22890
                     /locus_tag="NOB74_001718"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HCI1220907.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         7391 a         4028 c         4773 g         6765 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaaatgata ttttacgagg aggaagaaaa
      541 aatgaaaaat cggttaattg tcgcatgtgg aagtggagta gcaacgagtc agacaatcgc
      601 tagtaagatc caaagtatgt tagaagatga cggcatcgca tttcctgtag aagcagttga
      661 ttacaaatcg attcaaaatg agcttctaac tgctggaatc tatgtgtatg tcgcacaacc
      721 tgatgaggaa gtacttgaac aagcaaaaga tttgggtatt gaagtatttc caggaattcc
      781 atttttaact ggaatgggtg tagaacctat ttatgacagt atcaaagagt tagtacagta
      841 aaggaggatt gttggataaa aaagttggtt catagtttta tttactatat ttagaaagaa
      901 agaaggttta tttatggaag ttttccaaac cattatcaat tatgttttga acttaggatc
      961 agccattttt gttcccctga ttattttgat acttggattg ttggcaggga tgaaattaaa
     1021 aaaagcattc atgtctgctt tgactttagg gattgctttt agcggaatgt ctatggtcat
     1081 tggctatatg tctaacgcag taagtccagc atcagaagca ttggctaaaa atacgggaat
     1141 cagtttgcct gcacttgatc ttgggtggac aggtgcagca agcatcacat ggtcgtggag
     1201 ttatgctttt atattttttg cagtaacgat tggggtcaat tttgtactgt tactttttaa
     1261 ttggacgaag acgttaaatg ttgatatgtg gaatgtttgg gggaaagctt taactgctta
     1321 tttagtttat tatgtttccg gtagtttggc tgcaggcttt cttactgcaa tggtccaagt
     1381 tatattggaa ttaaagcttg gtgatatgtt tcaaaaacat atacaagatc tcacagggat
     1441 tccattagta acagtgactc attttatgac atctgccgct gtcttgttgc tgcctttcaa
     1501 tatgatcatg gataaaattc ctgctttaaa taaacgagcg gatacgaatg cattgaagaa
     1561 gaaaattggg atcttctctg aaaactctgt aatgggattc attattggat tggggcttgg
     1621 ctttgctgct gcgtatggcg tttcaggttc tcttaatcta gcgatccaaa cagctacagc
     1681 attaagtttg tttcctatga tctctaaaat gttcatgcaa tctttgtctc ctctagcaga
     1741 cgctatgtca gaatttatga aaaagcggtt taaggatcgt gaagtatata tcggattgga
     1801 ctggccgata ttagctggtc gttcagaaat ttgggttact gctattttac ttgttcctgt
     1861 gtttattggt tatgccatta ttttgccagg aaaccaagta ttgccattag cagggattat
     1921 caactattcg attgcggtcg gcggattact tttaacagga ggaaacttgg ctcgtatgct
     1981 gatcttggga atcatcacta tgcctattta tttgtacggg gccacttacc ttgcgccaat
     2041 actcagtgat ttagcagaaa aaagcggagc agtcgaggga atcaagaaag gacagttgat
     2101 cacatggtca tccatagaag ggccggagtt cagggtttta tttgcggagg catttaatag
     2161 gaatattctc gctattgtag gatgcgtgat ttttctagga ctgtttgttc tactttataa
     2221 atatatgata aaagcgaaag taccgagtga acgttatgct gaactacaaa aatagcattg
     2281 aaatggtggg aaagtaatga aaagagaaga gacagataaa ataaaatgga cagtcgctct
     2341 ttgtggtaca cttctgctat ttctatatgg actctttact cagaatatca tcatcaatct
     2401 attggtcatt tttttcgcac tagtgatcta taaatatgga aatcacgttt tattcagaga
     2461 gtacgatgaa aaaagaaaac ggaaaataga agaatcaatg aaaataaaag aagctaccaa
     2521 agaaatattg agagaaaaaa gttttataaa aagataatgg aggggtcatt atgtcagatg
     2581 gacgtatgtt atttgagaga gaacgacagg acatggcacg tatcgtaaga gtgattttcg
     2641 aaaggaaaaa cacaaatgtc gcaggaggga atttttcctt taaaaccact gatgatcaag
     2701 ggaaagacta catcatcatg acgccgacca tgatgtcaga agcctatcta ggagagattt
     2761 ctcctgcaca ggttctagta gtagaaccaa gaacgcgtag aatcgttgac ggagtcggtc
     2821 atttaactcg tgaaatcaat atgcatgaag cgatgtatga gactaatcca gctatcaaag
     2881 ctgtcctaca tgctcatgcg cctaatgcaa tgttctgggc gactactggg ttgcctatgc
     2941 ctaatttgac agaagccaca gctaaagtaa aagagattcc tgtcatggac tttgagccta
     3001 attgctctga agaacttgct gaattgacaa gcgactatgt aaaaaaacag catctcgaat
     3061 taccgcatat gttgctgctc aactctcatg gcgtattgat caacacaggt ggagaatcag
     3121 gaatcgaagc tatccataaa gcactgcaaa tccttgatac agttgaatgg aatgcagaaa
     3181 ttgcctacaa gcagacgatt tttcaagcat tagggattac tgacggtttt tattcaaaag
     3241 gtgagaaaat cgggggattg gaagagttga aacataaaac ggctatttat aataaatctg
     3301 ttattgcagc tggtggagac taacctatct gacacaaaaa actacgactt tcacaaaatc
     3361 tgatccagat cgatatctgc ttcaggttgt attatgtaag tcgtagttct tttcttttat
     3421 ttagttaaga ggtggtctgt ccattccctc gcttgcttga tttcgtccat cgtcaactga
     3481 tgacctgtta cagttagctg aatagtcaca tttgcttggc gtgtttcgaa ttgatcggcc
     3541 aattctttaa aggaagcagg ggaaacgatt ggatcgttat caccataaga aatccagacg
     3601 gttttatcct ctaatgtgga acggctttga tgaacaccta gagacatcgg atggaaaaac
     3661 aaccctttat ttagctcggt ctcacgctcc aataataaat gagcagcgat gtttgcgcca
     3721 tttgaatagc cgacaagcag ccagtcactt aacggtatca gttctttttc gctgatttct
     3781 ttgatttttt catggagttt atctgtttct ttttccaaac tgtccaggtc gaattgattc
     3841 aatccattac gcttgaaaaa acgattcatc ccatcttctt ggaccgtgcc acgaaaagaa
     3901 agcaatgtac tgtttggtgc aagaaagtga gcgatatcca gtaaagaatg ttcatcgcca
     3961 cctgtgccat gaagtaagat caaatgcttg ccacttgttc ctttttcaaa aatgtaggtc
     4021 attttgttcc ctcttttctg tttctataga tgcaaatgaa gtagcatgaa gagattattc
     4081 acgtttttta tttgcatcac ttgtatcgaa aggacggaca taagcttcaa tggcttcacg
     4141 acgttcttct aagaatggag gaagagatag tttttctcct gctgattctg ctggttcatc
     4201 ttcaaggaat ccaggaccat cagttgctaa ttcaaacagt acgtgatgag cggctaggaa
     4261 gtactcagat tggaaataga aacgatcgac gaaaccagaa tttggcaatt caatcttatt
     4321 gattacttga atccagtatt ccaatgcttc tttgtctgct acacgcaatg ctaagtgatg
     4381 gatatttcca aatccttcga ttgcttttgg caagtctgtc cgatgttcaa taatgatgct
     4441 tgcaccattt cccccttcac cgatttcaaa taagtagaaa tctcctgaat ggtctgtttc
     4501 tttgaatcct aagatttttt caagaatcaa gcggatatgc tctaattgac tgacacggac
     4561 aaagacaggt ccaagtcctg tgatcgcaaa ctctgtcggt acattgctgt ttttccaagg
     4621 aatgccagct gctacacctt gattgttttc gtcagagatc aattgataat actgattatc
     4681 gaaatcttca aattcgatat attttttgcc gaaacgttca ttgattgctg aatgagtaac
     4741 gtcatatttt tcaaaacgtt ccaaccaaaa gtctaatgct gcgtcacttg gcacacggaa
     4801 agaagcacga gagatcgtat ctgttccttt ttttcctttt ggctgatttg gaaaatcaaa
     4861 gaaagtcata tctgttcctg gcgcaccagt atcgtctgta aagtaaagat ggtaagtttc
     4921 gatgtcatct tggttaactg tttttttgat taagcgcatt cctaaaatat ctgtaaaaaa
     4981 gcggtagatt tttgtagcgc tagatgtcat tgctgtgacg tggtgaattc ctctgatttg
     5041 tgtatccatg ataaatttcc tcctgttaac ttacaaaaag taagtagttg atttagacat
     5101 agtatagagg gtgcatctct attttgcaat taatttgtct tctaaagtat caggaaggaa
     5161 tcaagaatgg aaaagaggag ggacggatca ataaaataaa aagacttacg actagctgta
     5221 tcgatttcaa aaaaactagc tttaaaaagc taactttaga atcattacgg gtggtcataa
     5281 gtctttttat gctgagttat tttttcattt ttgagctaat gcttaggata gaatagaatg
     5341 ttgatttcac gatctcttct tgttacttga aactgcttac cactgtcacg atctcttggt
     5401 aaacggcttt ttcacaacct ctttggttaa gttgaacgca catccagcac agaatagttc
     5461 cgaacatcaa atcggtttcg gctggaagaa tattcaatcg gctgtccatc tttgagatag
     5521 acgacttgct gaacttccag tacaggatcg ttttctgcac agttcaaata ttgctgatca
     5581 tattcatcac ttttatctgc agaaatagca cgataagccc ctgcaaaatg gacattcaat
     5641 tcttgatgaa gatgatcata gatagaggct aacaaatgtt ctttttttaa acccggcaca
     5701 agatggactg gcataaaggt atgctctaaa acatatggct cgccatctaa gatccttaac
     5761 cggtgaatat tgtagacagg ttgctcggca tcgatcatca atcgttcttg gatatattga
     5821 ttagggaatt caacatcaaa atgaatgatt tgactcttca aagaacgatg tctgcgtttc
     5881 atttggagac tcaaaccttc atactcgtta gcgggcgatg tgtctttttg cataaatgga
     5941 tgattcaaga ttttcgttcc tgatcctcgc tgcgaataga caagtccttc cattgctaag
     6001 atattgatgg cttttttgat tgtcatccgg ctcgcaccaa attcttttac caagtcgact
     6061 tgattaggca aaaaactatc gagaggatac tcttttgaac ggatacgttc tcttaaaata
     6121 tttgcgattt cttcgtattt tggcacgtta ttcacctctt ctagagtata acgaaagatt
     6181 atgcttccga caactcgaag tagcatctgg aacattgttt attcgaaaaa agaggtcatg
     6241 acaagttttt gtcacaaccc cttaatgatc tattaagcaa tatctaaatc tggttgttta
     6301 tctagtactt tcaggaatgg gtaccagata aaggcaacga tgacaaagtc gatgacttgc
     6361 agcataccac caagccatga atttgttgct aagacaccgc ttgcaatgat tggcacagtc
     6421 catggaacag agacgccagt tggtgcaggg acaagtccag cagccattac caaataattg
     6481 aacgtcgtta cgattagagg tgccacaacc caaggaataa ggattgttgc attcaatacg
     6541 atcggtagac cgaagatcgc tggttcattt acattgaaaa taccaggtgc taaagctaat
     6601 cgtccaacat cacgatactg tttcttttta agaacaaagg ccatcaataa aacgacagct
     6661 aaagtcattc cagagccacc aataccaaca gtgaaggttt ccatgaatgg ttttgtgatg
     6721 atgtgtggta attcttttcc atgttgataa gcttctaagt tatcaagcat cagtgtattc
     6781 caaatcgggt ccattacaga gttgacgatg atttgtccgt gaagtccgaa gaaccataag
     6841 aattggacaa agaacaaagc aatcaatgtt gcaggtaaac tacttcccaa accagttaat
     6901 ggtttttgga tcacttcata aacgacgtca tgtaagttag cattgaaaat accagtcatc
     6961 acagcattga ttactaagaa aatagttagt gtcactacag cagggatcaa agcggcaaat
     7021 gattttgtta ctgcaggcgg aactccatca ggcattttga tctgccagcc gcgtttcgtg
     7081 attctgcagt agatttctcc agccaagaaa gcagcgatca ttccaatgaa cattcctttt
     7141 gcgccaagac gatcaagtga aagcacacca gtcacatctt caccgccagc ggttttcatt
     7201 gcaaaaggcg taagaatcaa gaagctggca aaagacacgg caccaccgaa aataccttca
     7261 acgtcataag attttgataa ataatagccg ataccaaaag taacaaaaac cgacatgatg
     7321 ctcattgttg cattttgccc attaccgaat aaattcgata aagttccctt tgttgcgtca
     7381 ctgaaaaaag gcaagttatt gataacgaca acgatcgaac cgaacatcgt taaagggaag
     7441 gaaagcatga aagcatcccg cagcactgta aggtaacgat tttgccctaa taaattagct
     7501 aagggcatga ttttctcaga aagcttgtcc ataaaaccgt tcatttttat tcacctcaaa
     7561 tttatttgca atcgattaca tacaaagtat aacgccaaaa attttaaatg tctagtcatt
     7621 ttcataaaaa gtattgattt attttttagg gttcgttatg attacggtat caagaaaaaa
     7681 gagaggaagt aaaaaaatga aaacctacac attcccagaa aatttttggt ggggttctgc
     7741 tgctagcgga ccgcaaacag aaggaagagt aagtgatgat ggtaaaggag aaaatatttg
     7801 ggatcattgg tatgaattag agcctgaaaa attcttcgat caagtaggac ctgaaaaaac
     7861 ttcgcaagtt tacacaaaat acaaagaaga tgttcagtta atgaaagaaa ctggccataa
     7921 cacatttcgt acatctatcc aatggagtca tttgattcca gaagggacag gtgaaatcaa
     7981 tcaaaaagct gtttcttttt atcgagatta ttttactgaa ttgctggata atggtattga
     8041 accttttgtg aacctttacc atttcgatat gccactacca ctgcaagaaa aaggcggatg
     8101 gttatcaaga gaaacggtcg acgcttatgt ttcttatgca gcagcgtgct ttgaactgtt
     8161 tggagatctg gtcaaaaaat ggtttactca taatgaacca atcgtacctg tagaaggagg
     8221 ctacttgtat caattccact atccaaatca tatcaatatg aaagaagcgg tccaagtagg
     8281 ctatcatgag aatctagcaa gcgcaaaggt aatcaaagcc taccatgaag gcggacatga
     8341 tggtgagatc ggaatcatct tgaatctgac accaagctat ccgagagatg aaacgaaccc
     8401 agaagatgta aaagcggcga agatcgctga cgcattcttc aaccgatcat tccttgaccc
     8461 tgcagtgaaa ggagagtttc cacaagagtt gatcgaaatt gtcaaagaat tggctataat
     8521 gccagagatc catgaaggag acctagaact catccgtgaa aacacgattg acctgctagg
     8581 aatcaattac tatcagcctc gtcgaatcaa agcaaaagaa actccaatca atcacgaaca
     8641 tagccccatg ccagatgatt attttgataa ttacgacatg cccaataaaa aaatgaatcc
     8701 atatcgtgga tgggaaattt acgaaaaagg aatctatgat attttaacga atacaagaga
     8761 aaactatggt aatatcaaat gctatatttc tgaaaatggg atgggggtcg aaggagaaga
     8821 acgatttgtt aacagcgaag gaattattga agatgattac cggatcgagt ttgttacgga
     8881 tcatttgaaa tacgtccatc aagcaatcca agaaggaacc aattgtgtgg gttaccacat
     8941 gtggacatgt atggacaact ggtcttggac aaatgcttat aagaatcgct atggctttat
     9001 cgctgttgat ttggcacaag acggtaaacg gacgatcaaa aaatcaggtc gctggtttaa
     9061 aacggtctct gaaaaaaacg gatttgatgc ctgatatttt ttgataaaac gttcacaaaa
     9121 tgtttgttct aacactgtaa tcgtgctaca ctaacagtga aggaggcgtt tacaatggta
     9181 gatacttatc gtaatatttt agtagcaatt gatggttctg aaaaggcaga aaaagcattt
     9241 cttgaggcaa tcacgattgc caaacgaaat caggcaacgt tgcacatcct gtatgtcaat
     9301 gaagtaacag gcaattactt tggtgatttt gcatttgtta caacaagcct tcaggaagaa
     9361 ttggatgagg ttgcggaaaa ccagatgaaa gaacatcgaa acttggcaat tgaaaaaggc
     9421 ctgacagata tcgagacata tgttctttac ggttatccaa agacactgat tgctaatttc
     9481 catgaatcga aagaaccaat cgatctgatt gtcatggggg cgacaggtct gaatgcggta
     9541 gaacgtgcac tagtaggttc cactacttcc tatgtagtca accacgcatc atgtaacgtc
     9601 atggttgtaa aataaataaa ttaagggaac agaaagcaaa aaagcataac gcttcttttg
     9661 ctttctgttc cttttatttt tttgtaaaaa attactttac ctgatgaagt aatcatgcta
     9721 ttctaattac aacgacagat ggagtaatat ggaggaaaga aaatgatttc aagtgatgga
     9781 atacgcggat acaatgatgc gattatttta tcgatcctta acaaaaacga ttcttatgga
     9841 tatgaaattt ctaaaacgat tcgtgagagg acaaatgatt cctatgtgat caaagagaca
     9901 acactttact ccgtttttgc ccgtttagaa aagaatcaac tgattgtttc gtatcctgga
     9961 gaagtgactc atggaaaaaa gcggacatat tataaaatca ctgaaatagg gcgtaatctt
    10021 ttagaagaaa aaaagcaaga gtggctgacg acgaaagacg tagtcgatca atttttggag
    10081 ggaaattaaa tggatacaat ccgtaattat ttagacagtc tttttatcgg agtacctcaa
    10141 agtaccgaga tagataagct gaaaactgat ttgttggcaa atatggaaga ccattatcat
    10201 gaattgatgg gagaaggaaa aaatgaacag gaggccatcg gtacagtaat ttcgacattt
    10261 ggttcaatcg atgaattatt agaagaacta gatgtcgaaa aaaaacatca agctgacgag
    10321 acggaaacaa acacagcttc tatttattta agcgaagcag aaaactactg gaaagaatac
    10381 agagcggcaa gtctccaagt ggcatcaggt gttctattca ttagcttatc ttttgcaagt
    10441 tttcttttct tttgttcagc aggatatgtg ttcatgggta tttcttgtct gattttcggt
    10501 atagcattag ctgtcggttt ttttattgct tctggtatga aaatcacacg tttaaatcac
    10561 tttttgcacc atcggaaaat acctgaaaaa gtattagcag aagcaaaaga aaaagaagaa
    10621 gagtatcagc gaagttttgg cttctcactg attgcaggaa ttggattatg tattttttca
    10681 cttttcccac ttttggcttc tttaatgtgg tatatggatg gtagtatcgg tgcctctata
    10741 ttttttgtta cggtaggaac gggtgtcttc ttgatcattt atggcagtct agtccgtcat
    10801 tcttatcgtc aattcactca aagcgcttat tactggtgaa tgtattcaga tttgtaaaaa
    10861 tattctattt atccggcgta gaaaaaaaga ctgtgacacg cttttgtcac agtctttttt
    10921 atatataata atttaaaaat tcatcatcta aatccgtaga attttctaga ttgcttaccc
    10981 atgtaaaatc gttatagaca gatttcagtt gacttctgcg ccattgtaca gggataaaaa
    11041 gacgcatgct atcttcattg aatccgacta ataatttctt tccgtcagta atgatgggac
    11101 gttgtaacaa agtaaaatgc gagacgatca gatcgacaag ctctgaggtc gtacattggt
    11161 cgatttggtc tttcaaattt ttataatcaa tcgagcgttt agctaataga tcgtcaaatc
    11221 cgttttctgt taatgacaat aaataaaata tctctttcct tgttaaaggc tgtttaggtg
    11281 tgaaaattcg ttctctgtaa ggcatttgat ggtctttcag ccagtttgcc atcagatggt
    11341 aactatgtgt gcgagaagaa tagatcgtaa gcataaaaaa actccttaaa tagtccatta
    11401 atttgttaga tctgttgaga taaataatag gtaaggagct gtgcataagc attgatcaaa
    11461 acaacccaaa catcattaga aataactttc taaagtctta aacttgcgac gagaagcaac
    11521 tagactaata gaaaaaatgt cttagccatt tggcttcctg tttgtttttt tgcttatgct
    11581 gcagctcctc gggaaagggt tctaacaatt tgaagaaggt tgatgattga tctagtttaa
    11641 attgtgtgaa atttgaaatc tggtgttttt actagatgaa tcacctaaca actatgatta
    11701 taacttatag aacttctgtt ttgcattcgg ttttgttata gttgttataa agttttattt
    11761 tattacagaa catttttaat taataaagaa cagttagaag ttaaaattgc tgattcacat
    11821 agagtttatg acttcttgga aattcttttt caatcagttt tttcatctgt ttatgaaatt
    11881 cttttttttc agtaaacata aaggtttggg tatcgtaacc ttcttcatgt aggaaataga
    11941 ttattccttt ttctgtgttt tgcgtataag cttttatact cctgtctttt ttgaaagaac
    12001 agatcgtata gccatctatt tggtctggta gtcgtttgat tttcttcaaa atgacttttt
    12061 tatcctcaag tttcattttt ttcacctgac tttatttttt tcatatggaa atcatagcgc
    12121 ctttggttat atgaaaacaa gaaggatact gaaatatata taaatcaaat agtggttatt
    12181 tattattaga atagcgaata caaataaacg accactattt tctgatttat tgcaaatgtt
    12241 ttttcaaata aatttgatta ccaagaaaag gtagtggtat atttactgag ggatactttg
    12301 aaaaacatat gatagaaaca gtaacagtat tatgaaaaat ctttttataa aaatggagga
    12361 atcgatttga tggaagatca gtatgtacaa gcaatgacga tcgcaggatc agatagcgat
    12421 ggaagcgcag ggatgcaagc agatatgcat acattcttta caagaaatgt ttacggtgtt
    12481 tctgtcatga ccgcatgtgt tgcaggtaat tcttacggaa tcggagcaag tgtgacattg
    12541 ccaacagatt ttatcgacaa agaatttgaa ctgattgcga aggactttca aatacgtgca
    12601 gctaaaacag gtatgctagc agattcaaag ttgattgaga cagttgtaaa aaattaccaa
    12661 aaatatgatt ttggaccatt agtcgtggat cccgtaatcg taacgaaaca tggaaatctt
    12721 ttactagaag aatctgcttt gcaaagcttg aaagaaaagc ttgtcccttt ggccgaagta
    12781 ctgacaccta atttttatga agcagaaaag ctgactggac ggacattagc agctgaagaa
    12841 gattttgtgc aagcagcaaa aggactgcaa gatatgggtg caaaaaacgt tatgatcaaa
    12901 ggacatcatg ctaaaaatgc gcagcaagaa acagtcaatg actacgtatt gttcgaatca
    12961 ggaaaatcat tttggttaaa tgcaccattt tatcctaccg accggatcaa cggaactggc
    13021 gattcgctat ctgcatgtat tgcagctgag ttagcgaaag gaaaaacagt tgaacaagcg
    13081 atccgattgg caaaagacta tgtaaaccgt gcaattcgtg aagaaataaa tgtagggcac
    13141 aaatatggcc ccatcaatca ttgggcagct ggtgaattag agtaaaagaa agaagttgtg
    13201 aaaaagttgc cctgcatcaa gtaataagaa cagccaagta aaaacagctt cttatgtttt
    13261 taacttggtt ggacttatta ccgcagatgc aagcttttga acaccgttta agaaagaggt
    13321 cgtgagcctg ccgtccagct ccgagtcaca aggaacaagt tcaaaaaaca gcttctcatg
    13381 tttgttgaat attgtgactt gtgaccgagg agttggcagg agaacaccgt ttgttcggaa
    13441 gaagggactg tgacaagatt tttgtcacag tccctttaat cttagtatat ttttctctac
    13501 ttgaataaaa aaattatagg attggagaaa ataatcgaga aatttgttgc ttgaataata
    13561 gccagttaga catttccttg actgtttcag ttgtcatgga tgaacaatgt gtctcatctt
    13621 ctttgaactg agtagcaagt tcttctaaaa actcaggatc gtaaatgaca gcacttgttt
    13681 caaaattcaa tcggtagcta cgaatatctt gatttgctga acctaccatg cagatttcat
    13741 catccattat caatgttttt gcatggagga agccgttctc atagacaagg atttgtacat
    13801 tttccttgat cagctgccga gcataatatt gtgttgctcg ataaataaaa ggatgatccg
    13861 gtttgttggg aatcatgatt ttcacatcta caccagaggc agttgcgatt tttaaagcag
    13921 caatgacact ttcatcagga acaaggtaag gtgtctgtat ccaaacacgt tttttagcag
    13981 aagtaatcaa tttgataaat gaaagcttga tttgttccct ttcgttattc ggtccgcttg
    14041 aaacaagctg gatggatgta tcagcaagct tagattcatc tcgatctgct tttttaaaga
    14101 aataattcaa atgatagccg accttttttt cttcaggtac cgagacgttc cagtctgtta
    14161 agaagcgaag ctggagcaaa gaagaagcgg caccgaaaat ccgtatatgc gtatcgcgcc
    14221 aatagccgaa tttttttgtt gtatttacat attgattggc aatattgaaa ccaccggtat
    14281 aactaatctt tccatcgatc acaacgattt ttcggtgatc atggtaattc aatcggaaac
    14341 gaagtaatgc cctttgtgag gtaacaaatg tatggacatg tccaccattt ttgattagac
    14401 gattgaaatc ttttgctttt gtgccatgag agccaaatgc atcatataat attcgaactt
    14461 ccacgccttc tgcggctttt tcttctaaaa catgtaagac ttgctggccg atattatctg
    14521 tcacaaatgc gtaatattcg atatggatcg aatgtttggc tttttttaga tcttgaagca
    14581 gtgaatccaa tttctcttgt ccgtctgtga gaagagtgac agaattcatt cttgtcagcg
    14641 gcatacgatt taatgaagag aagaagtcaa caaattgctg tttgtcttta tcgcccatgt
    14701 caggatcgta atgttcaatg gtatctcctc taaaagactg aaagttttct aattctttca
    14761 agtcactttg tcggagatag aattttttct tatccgttaa tccacgtccg aaaaataaat
    14821 ataatacaaa gcccacccca ggaagggcaa acaatactaa gagccatgcc caaatggctg
    14881 ctacatctcg gggtttgatc aaaatagcca ccaaagcaat aagtgcattt aatagataaa
    14941 gggcggttat aatactagat accacaaaaa tgttcctcct tacatacaat aacattagta
    15001 tagcatgata gaagaaagaa gcctaccaag gtgaatatac ttttcactcc tttcatgaaa
    15061 atgtaggtaa atcgggctaa agtagttgct ttttgtaggt taataaggta ggatattagt
    15121 acagttgaat atctccttag gggagtaacc ggcaacgttt gttgcgataa tatcaacagt
    15181 aagttaacca aatggttttc tggtattgta tgaaatggtg agacctaaga caaatgcgta
    15241 tttgtcttag gtctcttttt tttcagacag gactagggcc aagatcaaaa aatgggggat
    15301 gaaatttgga aaacaaggaa caagcacaac aagcggtcta taaagaaacg atcgactcgt
    15361 tgatgcagca aacgcagagc tcaaccgatg gattgagcac cacgcaagcg aaggaaaaat
    15421 tagaaagaga tggcttgaac cagctaaaag aaaagccgaa gaagccaact tggaaattgt
    15481 tcttagaaac tttcaaagat gcaatggtta tcgtattgct gattgtcgca ctgattcaga
    15541 tggtcatggg tgactacatc gaattcttag ttatttttgc agtattgatg ttgaattcta
    15601 taatcagtgt tgtccaaaca aaaaaagcag aaggttcttt agaagcgttg aaaaaccttt
    15661 cagcgcccga tgctcgagtg attcgtgatg gtaaggaaaa aacgattccg gcaaacgaac
    15721 ttgtggtagg agatatcgtg ttgttagacg caggcgatta tgtacctgct gatggacgtt
    15781 tactagatgc gggatcatta aaagtagatg aaggtatgct gacaggagag tcgacttctg
    15841 cagaaaaaga agtaacggat atcacaagta cggtaccaat cggagatcgt acaaatatgg
    15901 tattcagtgg aacgatcgta acttacggac gcggtaaatt cttagtgact tcaactggga
    15961 ataatacgga gatcggacaa gttgctggcc ttttggaatc aacaactgag caagtcactc
    16021 cgttacaacg aggtctggat aaattcagta aaaaactaag tttggctatt ttggcattgt
    16081 ctttattgat tttaggtatc caactgtttc gtatttatct tggagaaggt acaggagata
    16141 tgactgcaga tatcgtcagc gcagtgatgt ttgccgtagc cgtagccgta gctgctattc
    16201 cagaagcatt acagtctatc gtaacaatcg tgttatcttt gggaacgaat aaaatggcaa
    16261 aacgtcatgc cattattcgg aagcttccag cagttgaaac acttggttcg acaagtatca
    16321 tctgtacaga taagactggt acattgacac aaaacaaaat gacagttgtt gactactttt
    16381 taggtaatgg cgatactggg gatttcacaa atgacccttc aaaatggaca gctgacgaac
    16441 gtcgcttgat cgaaatcagt gttttagcga atgatgcatc gatcagtgaa gacggtacta
    16501 aattgggcga ccctacggaa gtagcgttta tcgactttag tgaaaaatta aaccagcctt
    16561 atcaggaaat ccgaaacaac tacccaagac aagcagaact tccttttgac tcagatcgaa
    16621 aattaatgtc tactggacac acaattgata acaaaaatta cttgtttgtt aaaggcggac
    16681 cagatatcgt cttccaacgc agtaaaaaag tattgctaaa tggtgaagtc gttccgatga
    16741 cggatgaatt gatgaaaaaa ttccaagagc aaaatgaagc tttttcaaca cgcgcattac
    16801 gtgtactagc ttttgcttac cgtccacttg ataattttga tttatcattt gaagatgaag
    16861 acgatttgat ccttgttggt ttgcttgcta tgatcgatcc tccacgtgct gaagtgactc
    16921 aggcggtaac agaagcaaga agtgcaggaa tcaaaacaat catgattact ggtgaccaca
    16981 aaacaacagc tgttgctatc gcaaaacaaa tcgggatttt tgaagaagga aacctggctt
    17041 tgaccgggac ggaactagat gaattgacag aagatcaact aaacgaagtt ttagaaaaag
    17101 tcactgttta tgcacgtgtt tcacctgaga ataaaattcg tatcgttcgt gcttggcaaa
    17161 ataaaggtca tatctcagct atgacaggtg atggtgtaaa tgacgcacca gcattgaaac
    17221 aagcagacat cggaattgct atgggaacgg gtacagatgt ggcaaaagat gcagcagcga
    17281 tggtattgac ggatgataac tttgcttcta ttgtcagcgc agtagaagta ggacgtaatg
    17341 tgtttgataa tatcaagaaa gctatttctt atctatttgc aggaaattta ggtgcgatca
    17401 ttgcgatcat ctttgcctta gttgctgact ggtccaatcc atttacagca ttacaactgt
    17461 tgttcatcaa tttagtcaat gattcactgc cagcaattgc attaggtaca gaaaaagctg
    17521 aacctgctac gatgaaccgc ccgccaagag atccaaattc aggaatcttt acggacaaaa
    17581 cattgatttc tgtaacgtat cgtggtgtgc tgattgggat tgctgttatc tttgctcaat
    17641 ggcttggcat gcagcattca cctgaattcg gtgtagccat gtcattttca acattgattt
    17701 ggtgtcggac attgcaaaca ttcccagcac gttcaaacac acaaacagct atccaagcag
    17761 ggttcttctc taacagaagt gtcttactag ctgtagttgt atgtagcgcg ctttactgct
    17821 taacaatgat cccaggactg aaagaagtct tctctatccc atcagcattt ggattgacag
    17881 aagtctttac atgtatggga atcgcacttg tgacaattgt tttgatggaa atcactaaat
    17941 tgatcattgt acgagtacaa ggaaataaat aaaacgaatc aacgaggttg tgagcctgcc
    18001 gtttaattct gagtcacaag gtgcaatttc aacaaacagc ttctcatgtt tgttgaatat
    18061 tgtgacttgt gaccgaagag ttggcaggag aacaccgttt aaggaagaag ttgtaaaatc
    18121 agcattttga gctaatactg agggtcatct gattggacac tgtttattcg gaaagaggga
    18181 ctttgacacg actttggtca cagtcccttt ttttatttat gatagacgga aagccaatca
    18241 ttttattatt catcaaaaga gatagaatag ataaaagagg agaatgattt attccgaaaa
    18301 gtgaaaacat ataacaaaaa attagaggaa atcaaatgaa tgaaaaagaa tgggatgaat
    18361 ttgctgaaga atattatgaa atccagcaag aatcgcaagt aactattgct gaagatgtaa
    18421 aaaattatct gaaaacggag aaagtcctgc ctgctgaaac agcagcagac gttgctggag
    18481 gatctggcag atttctttcc ttagcaaaag aaattaatcg ctatgatttg atcgattttt
    18541 cttcaggaat gctagaaaat gcaaaaaaag aagcagaaaa aaatgagttg ccaaatgttt
    18601 cctttatcaa acagtcgtta gaagaattta tccaatcaaa tgagacatat gaaatggttt
    18661 ttacagcagc aaatccagca ttggtacatc ttattcaatt agaaaaattg atgaaaaagt
    18721 caagcaaatg gtgcgtgata atcagagtag tggaatcaat cgatgatgtt ttttatccta
    18781 tcgaaaagca actaggaatg atagaagaag atcctaatac atcgccagtt gtaatggatc
    18841 aatttgaaac atacttaatt gatgaaggat tcaaagtgaa gaaaaaagat tttacttatt
    18901 ttacacagga atcaattact gaagaattga tgaagctata ctatgacgcg tacgcaaaag
    18961 atcctgttgt gaccaggtac attcgcaaac tattcagtga aaaacgagaa atccttagta
    19021 cgactaagct gacctataga ctgctccttt ggtccgcaga taaaaaaaga acctttcacg
    19081 actcgtgaag ggttcttttt atgattttat tatattttgt agtaacgaat atcattttcg
    19141 atctttgtaa tcgaaaaagg tacatctgaa gtatattctg cacattctcc gtgttcagga
    19201 agcgtctcac tgaaaatcgt ttcatattcg tcaacagtga tccgtgttcg agaatctagc
    19261 atctcttgat gagattgtgc gaagagatat tcttgatagt tttcttccag ataacctgta
    19321 aaaaattcac ttactgcacc agaaccgtag ctgaatagac cgatgcgatc tcctggctgt
    19381 agtgatttcg aattttccag tagagaagtt agccccaggt ataatgaacc agtgtaaaga
    19441 ttaccgattc gtcggctgta acggatgctt tcttcatagc gagccataag acgttcctga
    19501 ttttcttcgt ctgtttggtc taatacgctt tgcaatgcct tttttcccat cttagtatac
    19561 ggaatatgga aagcaatcgc ctgataatct tcgagtcctc gacccgacaa ttctttatgt
    19621 cgattccaaa ctttttggaa tgattcgata tacgtagaat tagataaagg accatcaaca
    19681 acaggaaatt cgctataatc tggacgccag aaatcataga tatcttctgt cagaaatacg
    19741 ctgtcgtctt caatcgataa aatacgcggg ttttgagtga tcatcatcgc aacagcaccg
    19801 acaccttgcg tcacttcacc accgcttgcc aagctgtaac gagcaatatc acttgctatg
    19861 actagtactt ttcgttctgg atgatttttg acatattctt tcgccatgtg caaagctgcg
    19921 gtgccaccgt agcaagcctc ttttacttca aaagaacgag caaaagattg gattttcagt
    19981 aaatggtgga taattaccgc actcgctttt gaatgatcaa tcccggattc tgttccgacg
    20041 atgaccatgt cgattagctc acggtctttt tctgttacga ttttgctggc agcatttgct
    20101 cctagtgtaa tgatgtcttc atttgcacga ttgactgcca tttggtcttg accaatccct
    20161 atatggtatt ttgcaggatc atccccacgg ctttctgcca actctgtcat atctaaatat
    20221 aaattaggaa taaaaaagga aagacgatca atccctattt tcatttcaac acctctttac
    20281 ttatgataaa aaacttactt tactaaggta tcataaaaag attaaaagaa atataaaaaa
    20341 gagaatattt aaggattgtt aaaatttaat cttagaaaaa aataactgga acaagagcta
    20401 tttgttttta cagcaaagaa tggtatattt ttgtaggagg tggcttactt gaaagaagtc
    20461 gttatgatag atgctgcaag aacgccgata ggaaagtatc gcggaagttt aagtccattt
    20521 actgcagttg aattaggcac acttgtgact aaaggattat tagataaaac aaaactgaaa
    20581 aaagataaaa tcgatcaagt aatatttgga aatgtcctgc aagctggtaa tggtcaaaat
    20641 gttgccagac agattgcttt gaacagcggt ctccctgtag atgtcccagc aatgacgatc
    20701 aatgaagttt gcggatctgg tatgaaagca gtgatcttag cacgccagct gatccaatta
    20761 ggtgaagcag aacttgtgat agccggcgga acagagagta tgtctcaagc acctatgctg
    20821 aaacagtatc agtcagaaac aaatgaatat ggtgaaccaa tttccagtat ggtcaacgac
    20881 ggattgactg acgcattttc aaatgcacat atgggattaa ccgcagagaa tgttgcaaca
    20941 caattttctg tgagcagaga agagcaggat cgctatgcct tgtcgtccca gttgaaagca
    21001 gcacatgctg tcgaagccgg tgtattttct gaggagatca tcccagtcaa gatttctgat
    21061 gaagacgtgt tatctgagga tgaagcagtt cgtggaaata gtacattgga aaaactgggc
    21121 acgttacgta cagtattctc agaagaagga actgtaacag caggaaatgc ttccccgttg
    21181 aatgacggtg cctctgtggt gatccttgca tccaaagaat acgcagaaaa taataatctg
    21241 ccttatttag caaccatcaa agaagtagcg gaggtcggta ttgacccaag tatcatggga
    21301 atcgctccaa tcaaagccat tcaaaaattg acagatagat caggaatgaa tttatcaaca
    21361 atcgatcttt ttgagatcaa tgaagcattt gcagcttctt ctatcgtagt tagccaagaa
    21421 ctgcagttag atgaagaaaa ggtcaatata tatggaggag caatcgcatt aggccatcca
    21481 attggtgcaa gcggtgcacg tatcttgact acattagctt acggattgct tcgtgaacag
    21541 aagagatacg gtattgcttc attatgtatt ggtggaggtt taggcttggc agtcttgtta
    21601 gaagcgaata tggagcaaac acataaggat gtgcaaaaaa aaaagtttta tcagcttacg
    21661 ccatctgaac ggcgcagtca attaatagaa aaaaatgtat tgacacaaga aactgcgttg
    21721 atttttcagg aacaaacact ttctgaagag ctctccgatc acatgatcga aaaccaagtg
    21781 agtgaagtgg aaatcccaat ggggatcgcg cagaattttc aaatcaatgg caagaaaaaa
    21841 tggattccga tggcaacaga ggaaccatct gtcattgcag ctgcaagtaa tggtgcaaaa
    21901 atctgtggaa atatctgcgc agaaacacct cagcggctga tgcgagggca aatcgttcta
    21961 tcaggaaaat cggagtatca agcagtgatc aatgcagtta atcatcgaaa agaagagctg
    22021 attctttgtg caaatgaaag ttatccttca atcgtgaaac gcgggggcgg tgttcaagat
    22081 atctctactc gggaattcat ggggagtttc catgcatact tatctattga ttttttagtg
    22141 gatgtaaaag atgcaatggg cgctaacatg atcaactcga ttcttgagag tgtggcaaac
    22201 aagttacggg agtggttccc tgaagaagag attctattca gtattttaag taattttgct
    22261 acagaatcat tggcttctgc ctgttgtgaa atcccattcg aacgcttagg gagaaacaaa
    22321 gaaatcggtg aacaaattgc caaaaaaatc caacaggcag gggaatatgc gaagcttgac
    22381 ccttaccgtg cagcaacgca caacaaaggg atcatgaatg gtatagaagc tgtagtggca
    22441 gctacaggaa atgatacacg tgcggttagc gcttcgatcc acgcctacgc ggcaagaaat
    22501 ggattatacc aaggattaac agactggcag atcaaagggg ataaactagt tggaaaacta
    22561 acggtgcctt tggctgttgc cacagtaggc ggagcttcca atatcctgcc aaaagcaaaa
    22621 gcatctttag ctatgttaga tattgattca gccaaggaac tagcacaagt aattgctgca
    22681 gtagggttag ctcaaaacct ggctgctttg cgtgcattag ttacagaagg aatccaaaaa
    22741 ggccacatgg gacttcaagc tcgttcatta gcgatctcaa ttggggctat tggtgaggaa
    22801 atcgagcaag ttgcgaaaaa attacgtgaa gcagaaaaga tgaaccagca gacagctata
    22861 caaatattgg aaaaaatccg ggaaaaataa aaaagcaata tctttagaag aataaagcaa
    22921 gatttacagt tattttattt actgcagatc ttgcttt
//
LOCUS       DAIGWC010000043        22734 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.043, whole genome shotgun sequence.
ACCESSION   DAIGWC010000043 DAIGWC010000000
VERSION     DAIGWC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.043"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(26..1957)
                     /locus_tag="NOB74_001719"
     CDS             complement(26..1957)
                     /locus_tag="NOB74_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1220908.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="NOB74_001720"
     CDS             complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="NOB74_001720"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCI1220909.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2886..3638)
                     /locus_tag="NOB74_001721"
     CDS             complement(2886..3638)
                     /locus_tag="NOB74_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI1220910.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3798..4007)
                     /locus_tag="NOB74_001722"
     CDS             complement(3798..4007)
                     /locus_tag="NOB74_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220911.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4018..5345)
                     /locus_tag="NOB74_001723"
                     /pseudo
     CDS             complement(4018..5345)
                     /locus_tag="NOB74_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5481..5636
                     /locus_tag="NOB74_001724"
     CDS             5481..5636
                     /locus_tag="NOB74_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220912.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(5710..6297)
                     /locus_tag="NOB74_001725"
     CDS             complement(5710..6297)
                     /locus_tag="NOB74_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HCI1220913.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6380..7630)
                     /gene="clpX"
                     /locus_tag="NOB74_001726"
     CDS             complement(6380..7630)
                     /gene="clpX"
                     /locus_tag="NOB74_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HCI1220914.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7877..9166)
                     /locus_tag="NOB74_001727"
     CDS             complement(7877..9166)
                     /locus_tag="NOB74_001727"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HCI1220915.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9320..10252)
                     /locus_tag="NOB74_001728"
     CDS             complement(9320..10252)
                     /locus_tag="NOB74_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220916.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10409..11068)
                     /locus_tag="NOB74_001729"
     CDS             complement(10409..11068)
                     /locus_tag="NOB74_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCI1220917.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11071..12096)
                     /gene="sppA"
                     /locus_tag="NOB74_001730"
     CDS             complement(11071..12096)
                     /gene="sppA"
                     /locus_tag="NOB74_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HCI1220918.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12109..12399)
                     /locus_tag="NOB74_001731"
     CDS             complement(12109..12399)
                     /locus_tag="NOB74_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220919.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12808..14613
                     /gene="glmS"
                     /locus_tag="NOB74_001732"
     CDS             12808..14613
                     /gene="glmS"
                     /locus_tag="NOB74_001732"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HCI1220920.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14685..16040)
                     /locus_tag="NOB74_001733"
     CDS             complement(14685..16040)
                     /locus_tag="NOB74_001733"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HCI1220921.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16064..17233)
                     /locus_tag="NOB74_001734"
     CDS             complement(16064..17233)
                     /locus_tag="NOB74_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220922.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17230..18117)
                     /locus_tag="NOB74_001735"
     CDS             complement(17230..18117)
                     /locus_tag="NOB74_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HCI1220923.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18306..21998)
                     /gene="nifJ"
                     /locus_tag="NOB74_001736"
     CDS             complement(18306..21998)
                     /gene="nifJ"
                     /locus_tag="NOB74_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HCI1220924.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22197..22718
                     /locus_tag="NOB74_001737"
     CDS             22197..22718
                     /locus_tag="NOB74_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCI1220925.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT         6330 a         4939 c         4045 g         7420 t
ORIGIN      
        1 aaacccagcc tcttcttttt tatttctatg cttctgctac tgcaggagct tttctcaata
       61 aaccataaat cacaccagat acgactgctc cgatagcaat aaacaccaaa tacatgaccg
      121 ggtgactcag taagaataca acgaaaatcc cgccgtgagg agccagtaat ttgattccga
      181 aagctccgac taatccgcca gttaaagcag aaccaataat aaaacttgga atggcacgaa
      241 tcgggtcagc tgctgcaaat ggaatcgatc cttccgtgac aaacgatagt cccatcacga
      301 tgttcgtcaa accagcatct tgatctgttt tgctgaattt attcttaaac aaacgtgtag
      361 caacgaaaat tgccaatgga ggtaccattc ctccagccat aacagaagcc atcacgacac
      421 ttccgccagt tgcaacagtc gtagctaaag ttgctgtacc aaacacataa gcggctttgt
      481 tgattggacc gcctaaatct gccgccatca ttccagctaa taatgcacca agtaaagcag
      541 cattcgaacc actcatactt gtcaagaaac cgttcaatgc atcattgatt gctttcatag
      601 ggacattgac cagcaacatc aagaaaccag taatcagtaa gccaaacact ggataaaaga
      661 ggatcgtttt aattccatcc aatgattttg gtaagttctt gaataattta cgtaaaaata
      721 cgatgacata accagctaag aatccaccaa tcagtgcacc taagaatcct gcaccgcctg
      781 tattagctaa tgcaccagca gcaaatccaa cgatcaaacc agggcggtca ccgatacttg
      841 aagcaataaa tcctgctaat accggcagca tgaaaccaaa tgcagcttgt ccgatttggt
      901 tgaaccagct agcagcttga ttgtaattcc ctagatttga taattgatca tgtggcacgc
      961 caataaattg gtcgatcatg aaagaaagcg caatagcgat tcctccacca ataacgaaag
     1021 gtaacatgtg tgatacgccg ttcatcaaat ctttgtaaat tctttgtccg atagtaccat
     1081 ccgcatttcc ttcttctgaa ctgctttctt ttccatcacc atggaatact ggtgcagtac
     1141 cactaagggc tagattgatc aactcttctg gtttacggat accatcactg acaggacgat
     1201 tgatcagttc ttttccgtca aagcgattca tctctacttt tttgtctgct gcaacgatta
     1261 caccttctgc acgggcgatg tcttcagcag tcaatcggtt tttgattcct tctgaaccgt
     1321 tcgtttcgac tttgatctcc acacccattt ctttcgcttt tttcttcaaa gcatcttctg
     1381 ccatgtaagt gtgagcgatc cctgttggac aagctgtaac ggcaacaacg aattttcttt
     1441 ctggatgagc agaagcttct gcagcttgtg tttcttgttc tgctttttct tctgcttctt
     1501 tttgctcttc agctgtttgg aacaagtctt ggacttcttc tggtgtattt gcttctttta
     1561 attttcctac gaaatctgca tcaatcagca atcgagatag tgctgctaat gcttgcaaat
     1621 gtgtgtcgtt tgcgccttct ggagctgcga tcatgaaaaa cagataagtt ggctgtccgt
     1681 ctaaggcttc ataatctact cctttttggc tttttgcgaa taaaactgtt gcttctttaa
     1741 ctgcactgtt tttcgcgtga ggcatggcga ttccatcacc aagacctgta gaagtttgtg
     1801 cttcgcgggc tagaattcct tctttatatg tttcgatatc ggaaatccgg ccggcatcaa
     1861 acattttttg gaccatttca tcgattgcgc cttttttatc agtcgcttgc aaatccatga
     1921 tcatcgcttc tttgaccatt aaatccttga tattcatgat tatcctcctt gaaactaatc
     1981 aatttttgtg atttcaactt ctggcagcaa ctcatcaatc aattcgcgag ctgccaagtc
     2041 atcagaaaaa gctgttgcgc ttccgcaagc aactccccat ttaaaggctt cgattggatc
     2101 tttcgtacgg ctgtaagccc caataaagcc agcaatcatt gaatcccctg cacctactga
     2161 atttttcaat gggcgaacta atacattcgt tttataagtt ccttgttccg tgaagagcaa
     2221 agcaccgtct ccagccattg agatcagcac attctgtgcc ccttcagcta gtaatttttt
     2281 cccatacgga atgatttctt ctacagattg gaaggttgtg ttgtaaagct cagctaattc
     2341 gtgattgttt ggtttgatca acaacggttt cttaacaagt gcatttttta ggtcatcacc
     2401 tgttgtatca atcacgaaat ctgcaccttt ttctcgaatg atatcaatca gttcttgata
     2461 aaatcctttt cgcaggctag ctggcgcgct tcctgacaat acgacgatat ctccttgtcc
     2521 tactgttcct aatgcttgct tcaactcatc gatttcttca tctgaaatag atgggcctaa
     2581 gccattgatc tcagtttcag tgtctgattt tagtttgata ttgattcttg tatcttcttt
     2641 tacggttgtg aacaaagact ggatttgttc tttttcaagc cacttcgaaa taaattcgcc
     2701 agtgaaccct cctaaaaacc ctagtgctgt agattgagaa tcgatccgtt tcaaaatacg
     2761 ggaaacattg atcccttttc ctccaggtaa cttgaagtct tccttcattc ggttcaaatc
     2821 gcctagtttt aacccatcta cgcgtacgat ataatcaatt gatggattaa gtgttactgt
     2881 gtaaatcatt gtattgcctc cttaattgtt gtcttttcac ggaattcatt aacgaattct
     2941 aatggacaac gctcggttat gatcgtggct gcttccaaag gtgcaacaga ggtgaaggac
     3001 aactggttga atttggtatg atcaatcaat acaaatgtct cttcggaatt tttcatggct
     3061 aaacgtttaa cagctgcctc ttctggatcc ggagtcgtga atccttgttc aagatgggca
     3121 ccgttcattc ccataaatgc tttattaaaa tgaaaatttt ttagttgttc tatcgcatta
     3181 gatcctaaaa cagcattagt tgccagcttt atcgttccac ctaaaataat ggtagcaagc
     3241 tccaaatcaa ctaaatttgc cgcatgttga acggaatttg tcactactgt gatctgtttt
     3301 ccttgcagaa aaggaatcat ttctaacgta gtagagccag cgtctaaata aatgacatct
     3361 tcgtcattaa tggtttcagc tgccgatttg gcgatttgct gtttttcgtg aacgtttttg
     3421 agtgattttt cactcatatt ctgctcaaaa ttcaataatt gctctttctt agctccgcca
     3481 tgaactcttt ctagaaaccc actattctcc agctcttgta aatcacgtct tatcgttgat
     3541 tcagaagcat tcaaaaggtt tacaagatct tgtgatttca cgattttctg ctgttcaagc
     3601 aagtctagga ttttttgtct gcgttcctct gtaagcattt tcacgatcac ctcaatacaa
     3661 ataatagcat attttttttc tactagcaat ataaatcagt caaaaacgtt cataaaaatt
     3721 ataaatcagt caaaaaaaaa ataaaaaacc agtcagaaag actggttttt tatttttttg
     3781 tctatcatca agccgtttta tcgtttttta ttttcgcttc ttgttttttt catataaaca
     3841 gaagcaggtt ttctttcctt atgaagaaga taataataaa gtcccatccc gccaaacatg
     3901 accaaaaaac cgatgactga tcgaatagga aaattaggaa caaaaaagag acagacggat
     3961 aataatgatg ccggaaccat tattcgataa tagagttgtt tatccatttt cttcacctca
     4021 tattttttgt aaagtaatca attgttctaa ttctcggtaa tctaaaaatt gcacacgcag
     4081 atgctgctca cctttcttga catcgaattg gatacttcgc cgctttttct ttattcgttt
     4141 gaaggtaaca tcagagagtc tatgtttgat ttcctttaac ggtaattctg acagggattc
     4201 tgaaggaaca tagattctta aggataaaag atactcttga tatttttcat ctgttacctc
     4261 tacttctaga tattccctaa tataataaca ataagcttcg attccattat ccaaagcaac
     4321 agtcggatcg ataactttat agcacatcat gcgtgatcga ttctcgtcaa cccaaggaaa
     4381 atacgcctga gcatttagtg ttccgcgaac acgcctttct ttataatctc cttgttggat
     4441 atcataactt tttgttacaa aaaatgaagc attcttttta ggaacaggtt gcatttgtgc
     4501 attctgatac tggacagatt ggatcgtatg gtcagtgtaa atgtattcaa cgaatggcgg
     4561 tttcaataaa ccgacaccat tgtcccaagc aagatgatca aacccaagct ggtccctaaa
     4621 ataggattga aacatttgat tgtttggctt ttgccagtta aaggggtctc gataaagctg
     4681 gatacatatg acttcgtttt ctaattcctt cactttttct acttgttgga tgtcgagaaa
     4741 aatcggttta gggatgattt gatgataata gcgactataa tacatttccc aacacgaagt
     4801 gaaacataaa ccttggtaaa aaagatcgta tcctggaaat tggttgcaat cgactactac
     4861 ttccccgttt tgttgtttca ttttaggtaa atgttcgatt tcatcctttt tctcaaacaa
     4921 tagccgttga gagatctgtt ttgtattgtg atagataaac tcgctataag ctcgcatata
     4981 ggcgaacacc ccatgagcaa tcattttttt ctgaatgaag tctcgaatca aaaattgctt
     5041 ttctttgaaa acagagatag acaatacatt ttttatcaat aattgattat cttccaagcg
     5101 aaaactacat tcgttctcgt catttcctac aactaaccaa ctttcgtctc ttaccgatgc
     5161 tagcattatt ttttcttgaa gctttcgaag atcatacgga tccgcttgtt gtgtgaaaga
     5221 gcggataaat gttggctgga tcaacagacg tgtcaaaata gcccaatcgc ttatttcctg
     5281 tttttttctt cttcatttaa gtctgtgagc tggatagtca tcaataattt atcttcgcca
     5341 atcattttct cacctctttc aaatcttttt ataatttaat tataaccaat gataaagaaa
     5401 aactaaaact ttatgtctta gaaaccaatt tggacgatta catgatagac taagtaaaaa
     5461 gaaacaaaga ggtgtttaca atggggttga aatttgaacg tacagataat ttagataaac
     5521 ttttcgaatc atttgctgtc gatccggaaa aaacagttgc accaaaagaa gagatcgatc
     5581 gatttctaaa accacagcca caaaatgaaa agaaaaaaga caagaaacaa aagtaagtta
     5641 agctcaaaaa aagacttacc agccaaactt ttatgaaaga gtttgactgg taagtctttt
     5701 ttattctttt tatgattcaa ttgcttgttc gattgctgcc cacgcttctt cttttccctg
     5761 ttttgtaacg gaagaaaaga gaataaacgt gtcattgcga tcaaaatcca acgctttttt
     5821 gatttcgctc tcatgcttgt tccatttacc acgagggatc ttatctgcct tagtggcaac
     5881 aacaattaca gggatatcat aatacttcaa aaattgatac atctggatat cttcttgaga
     5941 aggcttatga cgcaaatcta ctaaagaaac gaccgcacgt agctggtctc tagtcgttaa
     6001 atatgtctcg atcatctttc cccattttgc tcgctcagtt ttggatactt ttgcataccc
     6061 atatcccgga acatcgacaa aatgtaatgc gttctcgatc aaataaaaat tcaatgtctg
     6121 ggtctttcct ggcttaccgg aagtacgggc taaattcttt cgatcaatca atgtgttgat
     6181 aaaagaagat ttccctacat ttgatcgtcc tgccagagct atttctggca attgtgtatc
     6241 tggatattgt tttggtgcca ctgcacttat gataatttca gcttgatgga ctttcatggt
     6301 ctctctcctt aacaaggtga tgaataaagc aagcggctgt cgcaaaagcc aaaatgactt
     6361 ttacggcagc ctcttttcat caacccgctt ttttctctga atctttatag attactgttg
     6421 gctcaccaga caattcagct gcttcttttg tgataatcac tttttcgatg ttttcatttg
     6481 aagggatatc aaacatcaca tccatcatga tttcttcaat gatggaacga agtcctcgag
     6541 caccggtatt gcgttcgatt gcttttttcg caatggctct caacgcttca ggttcgaatt
     6601 caagttcggt attatctaga gaaagaagtt tttgatattg tttgactagc gcatttttcg
     6661 gctcagtcaa gatccgtacc agatcatctg ttgtcaattt ctctaaagct gccataacag
     6721 gtaatcgtcc gataaactca gggatcaatc cgaattttag taaatcttca ggaatgatat
     6781 gctgcatgac actttcgtct tcagaaagtt tttggttttg tgtaccaaat ccaatcgtct
     6841 tttcgcccat acgattcttc acaatcgttt cgatgccatc aaatgcacca cctacgatga
     6901 acaatatgtt cgtcgtatca atctgaataa attcttgatg tggatgttta cgtccgccct
     6961 gaggtggcac acttgcaaca gttccttcta gaattttcag caaggcttgt tggacacctt
     7021 cgccggaaac gtcacgagta atagatacat tttcgctttt acgcgcaatt ttatcgatct
     7081 catcaatata gatgatccct ttttctgcaa gttccacatt gtaatcagca gattgaagca
     7141 atttaagcaa aatgttttct acatcttccc ccacataacc agcttctgtc aaacttgtcg
     7201 catctgcgat tgcaaaaggt acattcaatg tttttgctaa tgtttgtgct aaaaatgttt
     7261 taccagaccc tgtaggtccg atcaagcaga tattgctttt ttgcagttca acatcatctg
     7321 tgttttcttg tgcttgctga ttgacacgtt tatagtgatt gtatacggca acagctaacg
     7381 agcgttttgc gcgatcttgt ccaatcacgt agttattcaa tacttcaaga atttctagtg
     7441 gtttagggac ttcagtgaat tcgcgtacag cttcttcata aaattcttca tcaatgattt
     7501 ctttacatag gtcgatacat tcattacaga tgtagacccc tggaccagct acgatctttt
     7561 tcacttcttc ttgggttttc ccgcaaaaag aacagcgtac ggtctcattg ctacttggat
     7621 tgtcatacat ggtcttcacc ccttaacttg caaaaagtat gcaagaaact atcaaagact
     7681 ttacagtctt ttactatcat aacatagttt agtaaaaaga aaaagtgttt aacaaaggat
     7741 caactgacct atacctttgc attttttact cttaacaaaa aataaggaac tgtgacaaaa
     7801 tcgtgtcaca gtcccttatt tcgaataaac aattttctag aagtagcttc ttcagaaatg
     7861 atttattact tgatttctat tctttcgctt ctgtcgctgt acctgtgatc aattcgattg
     7921 cttttttcat tgtcacatca tgttccagca tatcttctgt caacacgcgt ttgatttgtt
     7981 cgattggcat gttgtatgtt tctgataatt cttggatttc tgcattgatt tcttcttctg
     8041 ttgcttgaag attttcagca gctgcaattg cttcgatcac aagatttgtt cttgtgcgca
     8101 tttctgcttc accttcgaat tgtttatgca agtcttcttc tgtagaacca gttaattgat
     8161 agtacatttc aggagagata ccttgacgtt gcatgttgtt caagaattcg tccattgaac
     8221 gatgtacttc atcatgaacc atcacgtgtg gcaattcaac gatttctgcg ttttcaacag
     8281 ccatacggat cgctgcttca tcttttgcat cgtccgctgc tttttctttt gtttctacta
     8341 attctttgcg atatttttct ttcaattcgt ctaatgttga tacttcgtca tcaacatctt
     8401 ttgcgaattc gtcatctaat tcaggcactt cttttgcttt tacttcatgg attgtcactt
     8461 tgaagactgc ttcttttcca gcaagatctt ctgcttgata atcttctggg aaagttacat
     8521 ttacatctag actttcacct gatttatgac caactaattg atcttcaaaa cctggaatga
     8581 atgagcctga acctaattca agtgagtaat tttcgccttt tccgccatca aacgcttcgc
     8641 catctacaaa gccttcgaag tcgattacta ctgtatcgcc attttcagct gcagcatctt
     8701 ctttgataac taattcagct tgtgcttctt gttcacgttt gatacgtgca tccacgtcag
     8761 catctgttac ttcacggtct tgtttttcaa caactagatc tttatattgt cctaatttta
     8821 cttctggttt cactgttact tcagcagtga ttacccagtc ttgacctttt tccatgcttt
     8881 caacatcgat ttttggttga gaaacaggat cgatgccagc ttctttgaca gcagcttcat
     8941 aagcttctgg taatacagca ttcaatgcat cttcatataa agcttcttca ccgtacatac
     9001 ggttgaatac ttgacgagaa actttccctt tacggaatcc aggtacgttc aagctttttt
     9061 tcactttatt aaacgcagtt gttaatcctt tttggatttc gtcttgcgca atcgtaaatt
     9121 ttaaaacacc atcattcgtg cctttttttt caaatgttgc agtcatttaa ttccctccga
     9181 gtttagaaat tcattttata catcaaaaac gtttcatgca tacctttaaa tagtacacta
     9241 accctttcaa attgtaaaca tattgaatgg atagaatcct tgtttttcat aacattttta
     9301 tctttttcac tgataaaatc taatggaaga agatcatttg ctgcaaaatt ttttctcttt
     9361 tttttaaaaa atcttgtttt tcatcttctg taccttcata catcgttttt cctgtacacg
     9421 cctctacagt cagttgaaac cagcgcttcg ggtcttcgat gtatgtatca tagacaggat
     9481 aaacaattgc agattgcaac gtgaattctt cttttaacac ggaactaagc agcgcatctt
     9541 cattcccgta acgatctgaa aatacacata attgctggta acttgcctgc tgctgcggct
     9601 ttggcagatc ttttggtatg actttgacta acttttcttc aatcgtcaaa tagaaaacag
     9661 gatggcattc gttcaattgc ctaagtgtct ccagtaattt tgcccttgct aaaatatgga
     9721 cctctggcga tacaataagt ttactcgctg tttggataaa ctcatgataa ggaagctgtt
     9781 cgatctcatc aatagacgca agctgacgtg caggttccaa cgaaggaagt tcctccgatt
     9841 tattgtggag tgccttgatc ttctgcctct ccatttgtcc ggataattct tctgcaaatt
     9901 ggattttttc aatgacccgc tgctcgaaag cttcataaaa atctgtactt gctatcaatt
     9961 ttctagcata taaaaaatct tgtgtactga ttaacaagtc aaaataaaat tcagcaaact
    10021 cctcattttg aagatactgt ttttcatgca agagtgcttg cttcaatgct tcttttttct
    10081 cgtccaactc gtaaagacaa aaaacaagca ggctattagc ctcaaagctt tctttcaact
    10141 cgtaagctcg ttgaaataat tcttttgcct gctgatattg ctggtttgct agtgcttgtt
    10201 gtgccactcg cattaaattc tcatattttt ctggaaaatc aatcggcttc acgcagtgtc
    10261 ctcctcttgc tcatattcag ctcatgttca atagtagcaa aacaaaaaaa gcatgacaat
    10321 taaaaataac tgaagcaccc tctaaaagct agattttaga tctgactttt agaaggtgct
    10381 ttcaactgtt actgcttttt attgctcatc agctgttgac ttcctggttg aacgctttga
    10441 tcagattgat cgtaacaaca cttgtattag tgaaaaaatc gcccagatgt tgctttttct
    10501 gattaaagac tgctggaaga taccctaaca tcagcaaagg aaattttaga atgaaccggc
    10561 aagcaccttc tctaactaaa acggttgacc agctaagttc ttcttcatca aagctgatga
    10621 ctcgaatacc aaagatcatt ttcccaatcg tttggccatg attgaatttc gtcaataaaa
    10681 taaaatacgc tagataaata agtaaggctg tgaatccgta gagactcaga taagaatctg
    10741 aaaaattaag ccaacctaga tttttggcaa taccaagtgt taaacgcgta atagctccga
    10801 tacacaaaag atcgaccaag aaggcaaaca ttcggataaa aaaacctgca tagaaatact
    10861 taggaaaatc atttgctttt ggcggttcat ttcttgtgtc cgtatacttt ttccatttac
    10921 gttgtttctt tttgatttct tcgggcgtca aaggctctct ttcaaaagag ctcagtacct
    10981 tttgggaaaa gttggagtca ggtcctacag caggctgctg ttgcttatct ttttcttgtt
    11041 ccttattttc atttgaaagc tctgacatgc ttactcacct ccgtaataat acattgcttt
    11101 tggtgattcc gctgtcccta gattctcaag aacggataag atctgactag tctcagaagg
    11161 cttcaatccc tggaattctg ctagtttact tcctaaccat gtactagcaa acccagatgg
    11221 cgtggaagaa tattctacta gttccgcatc ttcaagctgt tgttcctttc gtatagcttt
    11281 taaagcatct tcaggaaatc ccaattcatc gactaaacct acttcttttg cttggacacc
    11341 atcataaatc cttccatcag caattttttt gacttcttct tcagatttat tccgtccctc
    11401 gctgacgatt gctacaaaac gactatatgc gctgtcgata tatgcttgaa gcaccgcttc
    11461 ttcttctttt gtctctggtc gcgttcctga acccatatct ttcaacgctc cgcttttaac
    11521 tgttgtatct tccacaccca gtttttctag aagtcctgaa taattcaatc ctgacatgat
    11581 cacaccaatt gagccggtca ctgtttcttc tgttgcaaag attttatctg cttgagcaga
    11641 aatatagtag ccaccgctag ctgccatgtt tttcatgctg acatacattg ggatatcatg
    11701 ttctttacga atcgtatcca atttcttagc gatttccgca ctttcgtaga caccgccacc
    11761 aggagaattt acttctaaaa agataccttt gactgttgga tcttcttcaa tcgccttcag
    11821 ttgttccata aaatttttat gattgtaacc ttcagaagca aataaacctg aagaccctcc
    11881 cgcagcaatc gttccatcta ctgataattt tacgattttt tgcgtactgt ctccctcttc
    11941 caacacattt ggagctagtt cttcatcccc atataaccaa ctgttcaatc cctcaatttg
    12001 atcgttttcc tgaggcttag tcaaactagc tgaaactaac gaaaccacaa ataatcctgc
    12061 agcaatcaga actgctgccc aacgtctttt attcattctt tctcctttct aatacaagtt
    12121 ttttatgacg atcacagttt ctgactgctc agaagtgtcg aaccgctctg ctttttcttc
    12181 ccgcgcatac ccggaaaacg actcttttgt taattcatct tctaccgtaa actcacgagc
    12241 ttgagcaact tccaaggcat caggtgcgat ttcttggatg ctatcccagc cagtatctaa
    12301 aaatattttc gtatcatctg atacaccagc tgatgcttcg aatttggaca attgtttttt
    12361 taacattccc agtgtcatga tctcaatttt tgaatccatt tttactcctc ctctatccga
    12421 ttactttcta ttgtaccgaa ctcctgaaaa agatgataga taaaaaccca ttattttttg
    12481 acataaaaag gacatttgac aaagaatttg atatatacca atttattttt tattcttttt
    12541 ttgttgacaa gaacattcgc aaaaggttat gattttaaat gtttccagat aaaaaacaaa
    12601 aaggaggata gttatacctt ttaggatagc gccaggtctg tgtaaacaga tgacgaggag
    12661 agggtttatc gaaagattcg gcggatggcc ctagggactg cactctacag aaaatccaca
    12721 aaaaatgtct gcaaagataa aacaaaagga ttttcctgca gctggaagca ttcatacgaa
    12781 ttcattatag aaagtaggat gttttttatg tgcggaattg ttggaatgat tggattaaaa
    12841 aatgtaacac caggattgat tgacggtcta gaaaaattag aataccgtgg ttatgattca
    12901 gctggtatct ttgtctcaga tggcacaact gattatctgg tcaaagcaca aggcagaatt
    12961 caaaatttga aaaacaaaat aaatattgat actacaggaa atataggtat tggtcataca
    13021 cgatgggcaa ctcacgggca accttctgaa gaaaacgccc atccacatac ttcccaaagt
    13081 ggacgcttcg tgctcgttca caacggcgta atcgaaaact ttgaagaact taaaattgct
    13141 tatttagcaa atgaccactt tattggtgag accgatactg agattatcgc tcatctaatt
    13201 gaaactttcg cgaaggatac tacaacgcaa gaggcgtttt taaaagcttt gcgggtcatc
    13261 aaaggttctt acgctttcgc tttgattgat cggacagcac ctgatgttat ttacgtcgct
    13321 aaaaataaaa gtccactatt aatcggactc ggcgatggat tcaatgtgat tgccagcgat
    13381 gcaatggcta tgcttgctca tacgaaggaa ttcgttgaga ttgaagatga agagatggtt
    13441 accgtcacat cagaaaaagt tattattcaa aattttgcag gtgacatcgt agaacgttct
    13501 tcattcgaag cacaagtaga tgcttcagat atcgagaaag gtacctatcc tttttatatg
    13561 ctgaaagaaa tcgacgaaca gcctattatc atgcgtcgta tcgctcaaaa atacgtaaca
    13621 gaagacaatc gtgtctctct tgatcaaaag ctggtcgata cattgtctga tagcgatcga
    13681 atctatatcg ttgcttgcgg aactagttac catgcggggt tagcaggtaa acagactttg
    13741 gaaaaattga cacagattcc tgttgaggtt catttagcca gtgaatttgg ctataacaca
    13801 cctcttcttt caaaaaaacc attctttatt ttcttgagtc aaagtggcga aacagcagac
    13861 agccgccaag tgctggtaaa aatcaaccgt ctcggctacc cttcacttac gattacaaat
    13921 gttgctggtt ctactctttc gcgggaagca tcctttacac tgctattgca tgctggaccc
    13981 gaaatcgcag tagcatcaac gaaagcttat actgcacaaa tagctgtact aactttatta
    14041 gccaaagcta tcggtgataa aaaagaattt gaaacttctc ttgtattcga tatcactcat
    14101 gaattgagtt tagttgctaa tgcgatggaa tcggtcatcg cccaaaaaga ttatttagaa
    14161 gagttggcag aagtatatct cagcgataca agaaatgcct tttacattgg acgtggtgct
    14221 gactacaacg tttctcttga agctgctttg aaattgaaag aaatcagtta tatccaggca
    14281 gaaggttttg ccgctggcga attgaaacat ggaacgattg ctttgatcga agaaggaaca
    14341 ccagtgatcg gaatcatcag tgaagaagtg actggtgcgc atactcgagg aaacctgaaa
    14401 gaagtcgaaa gccgtggcgc taaaacacta gttattgtct cagagggatt agaaaaggaa
    14461 agtgaccagc tggtgctacc aactgtccac ccttatctaa ctactctaac cacagtcgta
    14521 ccgactcaat tacttgcata ttacgcaacg ctattacggg gattcgacgt tgacaaacca
    14581 cgtaatttag cgaaatcagt gacagtagaa taataaaaga acaaggacca gtgtcagaca
    14641 tctgacactg gtccttgttc ttttattttt tatgaaaata tctcttaatc cagtccgatt
    14701 tcttctttga ctactgccgc gattttatcg acatagtaat taactttctc atcagtaggc
    14761 gcttctgcca tcactcgaag taatggttct gtaccggaag gacgaactag gattcttcct
    14821 tctgatccca tttcagcttc tgcctcttca atcacttttt tgattgccgg aacatccatc
    14881 gcaccgtttt tatcacttac gcggatattc actaattttt gcggatagat tgttacctct
    14941 gctgcaagct ctgataattt cttacctgtc tgtttcatga tattcagtaa ctgaattcct
    15001 gaaagcatcc catctccagt tgtgttaaaa tctaagaaaa tcatgtgccc agactgctcg
    15061 ccgccaaagt tataatcgtt tttgcgcatt tcttctacaa cgtaacgatc accaacttgt
    15121 gtaacgacat ctttcaaacc gattccttcc accgctttgt ggaatcctaa gttactcatg
    15181 acagtcgtaa cgatcgtatc ttttttcaat cgattttttt ctgccaagta tttagcacag
    15241 ataaacatga ttttatcacc gtcgacaatg tttccaagtt catccaccgc aataatacga
    15301 tcgccatcgc catcgaaagc tagtccagca tctgctcctt tttcaacgac catctcagct
    15361 aaacgttctg gatgggtaga gcctacgccg tcattgatat ttaacccgtc tggatttgtg
    15421 cccattgtat aaaaatctgt ttcaagatcg gcaaacaaac gattaacact tgttgaagtt
    15481 gctccgtttg ctgcatcgac acaaatggtc aaaccggaaa ggtcaccgtt gatcgtttgt
    15541 acaaggaatt gagaatattt caataagcct tctggaaatt cttctacagt tcccaatcct
    15601 tcagctgatg gacgaggcaa ttcatccact tcagcatcta ataatgcttc aatttctagc
    15661 tcttggtcat ctactagttt aaaaccatct gcaccgaaaa atttgattcc attatcttgt
    15721 gctggattat gagaagcaga aatcatgacc cctgcgcttg ctttttgcaa acgtgtcaga
    15781 taagcaacac ctggtgtaga gatcacacct agctggaaca cttcgatacc caccgataaa
    15841 agtcctgaaa tcagcgcttc ttctaacatt tgacctgaga ttcttgtatc ccgccctact
    15901 aacacgcgtg ggcgttttcc ttcttcttca tgctggctta ggacataacc tccgcaccgt
    15961 cccagcttaa atgcaagttc tggcgtaagt tccttgttgg cttcaccgcg tacgccgtct
    16021 gttccaaaat atttacccat agttgtaaaa ttactccttt aacttaattt tctgaggaat
    16081 ttgttctgct catttgtgtt gattcgcttg tttctgatgt ttcttctgta cttgtggtcg
    16141 agctgcttgt cccagattcc gaactggaag aaatggttgt tgtcgatggt tccgttcctg
    16201 aatcagcaga tgaaatactt ctactcgtac ttgtattttc ttgtgtccga ctgctcgtcg
    16261 aagcagagct actgcttgac gtttgcaaca cgggtgtaat ctccacacta actgattcgg
    16321 gcttgatact taacccctct tctactggta tttcaatttt acgagttgtt cgatgattga
    16381 tacctgagac attgatcggt acagcaatac tgtcaccgat cgatgcaagc aaatcgctag
    16441 agccgcttac ttctgcttcc agttttgaaa aactgaaatc atagctttct accccggcag
    16501 ctggtgttcc ttgctgtatc ccataaagtc gtaccgactt gcttggcttg atcgaatcag
    16561 ctctcactgt tacttgcact ggatcagaga cgatacttaa tacttcccct gctgcattca
    16621 gcgcctgtat tgggacctca ctattaatcc catcatctgt gaccatcgaa gcgtccacat
    16681 cagctactac tcgtttgatt tctgccaatg ttttgtcacc tgtagtgatg gagacttttt
    16741 taggactaac ggaagtatca tcaagttcat atccagatgg tgtgaacgtt gaaggaatca
    16801 acgtttccac atcgaaatct tttattacct ttttctcaac cgttactgta atagtcgatg
    16861 gttcgatctt tgctgtgaca gcactgctca aattttgaat ttttagcgga acttcatgtg
    16921 ttccttcgcc cagcttagtg atatctgctg tgacgcggaa catccgtgta tcttcgtttg
    16981 cctctgcatt caactgaact cggtttgcac tggaaagttt gacagtcact gcattttcat
    17041 atccatggat atagtagcgc tttgaatcat aagaaatctt gatcggcacc cccgtaactg
    17101 tttgattata cgcttcattt ccagaaagcg tatttggaac ggactggcca tttgcattga
    17161 agtacagcgc aatactgaac agcaatgcaa taaaactgta aagaatgctt gtccgtttct
    17221 cttttgagat catttgcgat cccctccctt agtcataccg tctaggaaag attgaatcac
    17281 gtttttcttg ttttttgttt tctcttcagc aattagttct ctacgcaaga ttgccaaata
    17341 ttcttgctgg gataagccag ccatcagttc attatctaac gtgatgctga cgtccccggt
    17401 ttcttcagag acaacgatgg taatcgcgtc actgacttcg cttataccga cagctgcccg
    17461 gtgtcgagtc ccgaattctt tagggatcaa catactttct gatagaggaa gataggcgct
    17521 tgctactgcg atctttcctt cttttacaat aactgcaccg tcatgcagcg gtgtattagg
    17581 aataaagata ttgatcagca gctccccagt gatatctgca tctaaagcaa tccctgtctc
    17641 aatatactca tctaatccag tatgacgttc gatagtgatc aacgcaccga tttttcgctt
    17701 ggacatatat tggatggctt tgtcaaaaga caagatcatc ttctcatctt cctgctgttc
    17761 gctttttgat tgtttgaaaa gcgaactgcg tccaagatgt tccagtcctc tccggatttc
    17821 cggctgaaaa atcacgatag cagctatcac cccgtacgta atgacttggt tcatcagcca
    17881 agacaaggtg tgcagaccaa tgatttccgc tacgattcgg ataacaataa aaatagctac
    17941 acctttcaga agctgaatcg cttttgtgcc tcgcagcagt tggatcagtt tgtatacaag
    18001 ataccagaca accagaatat caagtatgtt caccaaaaaa ttcagagaga acaagtcacc
    18061 ggaaaacatt tgctgccaat agtccaaatt aaaaagttcc ccgatttgaa atgacataaa
    18121 aagcctctct tctcttttga gatttcctct ctagtatatc atatgtttta attttagagg
    18181 ctgatatgct cgtatttttc ttgagaaaaa cgcataattt tcaagaaaat tgcaagtatg
    18241 cgttttattt ttctctgcaa taaatatttt taaacttcag agaattattc attatatttt
    18301 ttctgttatt tttccttttt ttcttttgta gcttgttcca tttttttacg tcgttctgct
    18361 ctggcagctc ttctagcagc tcttctttct tctgcttcaa ggtccgtcgt tttttctttt
    18421 ctagtcttaa cgggtacatc gatagattcc tctggttcaa gtcgtttctt gattttttct
    18481 aattctcccg tcagtgcagc atagttgtaa aaacgtgttt tagcgtcgtg gacagtcttt
    18541 tcaaataaag cttttgcaag atttggattt gcgttatcta gcgaggaaaa gcgaacttgt
    18601 ttcctcatga aatcaggcat agcagagaaa tcaggttttt tgtagtccaa agtcattggg
    18661 ttcttgtttt tttcgaccat tgtagggtta tatcgatata atgaccaata accagaagaa
    18721 acagcttctt ttgcttcttt aagcgattct ttcattccgc caagcaagcc atgtgtgata
    18781 caaggcgtat aggcaataat cagagaagga ccaggatact tttctgcttc ttcaaatgcc
    18841 ttgatcgttt gcatttgatt ggcacctgaa gcaatttgcg ccacataaac atttccatat
    18901 gtcatcgcca tcattcctag atctttcttt gaagcatact ttccactagc cgaaaattta
    18961 gcgattgccg aagctggtgt tgcttttgag gtttgaccgc cagtattgga atagacttcg
    19021 ttatccaaaa caaggatatt cacgtctgct ccgctggcaa gtacatgatc gatcccgcca
    19081 aaaccaatgt cgtaagccca tccgtctcca ccaatcatcc attggctgtt ttttacgaat
    19141 agatcctttc tcttgtatat atcctccagt tcagggaaaa ttgatcgttc gctttcgatc
    19201 gcagcttgca gttttgctgc tctttgctgc gttccttcac tctcaaacat gtgtactaac
    19261 cagtcttcca tcaattctcg tagttcttct gatacttttg gcaatacttc tttgattgaa
    19321 cttgccaaag cctcgcgacg agtctgtgcc gctagaagca taccataacc aaattcagca
    19381 ttatcttcca ataaagaatt tgaccatgca ggcccttgac cacattcatt ggtcgtataa
    19441 ggagaagcag gagaagcacc gccccaaata gaagaacagc ctgtcgcatt cgcgatcatc
    19501 attcgatcac cgaacatttg tgtcaataat tttacataag gtgtttcgcc acagcctgag
    19561 caagcgcccg agaattcaag aagcggttga ttgaattgtg tagacaagac agtattcttt
    19621 cctttgactg gatttgcttt ttgtcttaat gtcattgcaa aagcccaatt cacagcttgt
    19681 tctttctgtt cttcataagg cttcatcact aaagcttttt cttttgcggg acaagcctct
    19741 acacacagac cacaacctgt acagtcttcc actgaaactt ggatacggta ttttacgccg
    19801 tctgcgcctc gcatttctct cacgataaat ccttctggcg cttcttccat ttcctcttca
    19861 tctgctaaaa atggacggat ggcagcatga ggacaaacaa aggcacattc attacacatc
    19921 gtacagcgat cactaatcca ctcaggtact tctaaagcga cgccccgctt ttccatagaa
    19981 gccgttccta aaggcatttc gccagttgtc attccatttg ctacaagtgt accaacagag
    20041 agttgatttc cttcctgtgc attcactggt tcaagtattt cttgtatata accagtgttc
    20101 cttttattga ttttttcagg catctccaac gttctccaat ggtctgggat cgcgacttga
    20161 tgaagcagtt cggtcgtccg atcgattgct tgtatgtttt tttctacgat agccattgat
    20221 ttatgtccat agcttttcag ggcttcttct tttagcagcg gaagcacctc atcaaaagga
    20281 atgatgtcag ctaatttaaa aaaagccgtt tccattgccg tattgatccg gcgtcccaaa
    20341 ccgacttctt gggccaatct catggcattg atcgtataga atctaatgtt attttcagcc
    20401 aagtaacgtt ttaattttaa gggcagatgc gtttctaatt gttcgtcgct ccaaagagta
    20461 ttcaataaaa aaatgccacc tggcttcaat cctttgacca agtcatagct atgcaggtaa
    20521 gctggtgtgt gacaggcaac aaggtccgca tgctcgacaa gatacgctga acgtatcggc
    20581 gtatctccaa aacgaagatg agagacagtc agaccgccag attttttcga atcataataa
    20641 aaatagcctt gcgcatattt atcggtgtga tctccaataa tcttgatagc tgatttattt
    20701 gctccaactg ttccgtcaga tccaaatccc caaaacttgg cctggaatgt ttgcggttct
    20761 gtcaaatcca gactttcctt tggttccaaa gattgataag tcacatcatc cacgatccct
    20821 atggtaaacc gttttttgcg tatgcttggg tcttttttca attcatcaaa aactgctgag
    20881 atttggtcgg gagtcacatc tttagacccc aatccgtagc gaccaccaat aacagccggg
    20941 cgaagttcag aatcatataa cgcactttga acgtctaata agagaggttc tccacctgcc
    21001 cctggttctt tacttcgatc aagaacagca attgttttta ctgtatgagg caacttttgc
    21061 acgaatgttt ccactggaaa aggacgataa agatggatat tcaaaaaacc tgttttccgt
    21121 ccgtttgcat tcaagtaatc aatcgtttgt tcaatcgtct gtgcaactga tcccatagaa
    21181 acaatgactt cttccgcatc gtctgctccg taataagtca ccaagtcata agaagttcct
    21241 cgtaatcggt tgatctcttt catatatttt tgaacgattt caggtaattt atcataatag
    21301 gggttgatcg tttcccgttg ttgaaaatgg atgtctggat tctggttcgt accactaaca
    21361 gtcggatgat tgggattcat ccctcgttta cgaaatgaag ctaatttctc ctgattgatc
    21421 agaggagcta attcttcata ttccaaaact tcgatttttt gaatctcgtg actcgtacgg
    21481 aatccatcaa agaaattcaa aaaagggact tctccttcaa tagaagcaag atgggcaaca
    21541 ggtgctaaat ccatcacttc ttgtacactg ctttcagcta acatagcaaa tcctgtttgt
    21601 cttgcagcca tcacgtctcc gtgatctccg aaaatattca acgcatttgt cgtcactgcc
    21661 cgactagcaa cgtggaaaac acttggcagt agttccccag caatcttgta catattcggt
    21721 atcatcaaaa gcagcccttg tgaagcggta tatgtagttg tcagtgcacc agttttcaat
    21781 gatccatgga ccacaccagc tgctcctgct tcggattgca tttctactac ttttactggt
    21841 tgaccgaata cgttttcttt tcctgctgct gaccattgat ctactaattc agccatggtc
    21901 gaactgggtg ttattggata tattgcagca atctcggtaa atgcataaga aatatatgcg
    21961 gctgccgtat tgccatccat tgttttcatt tttcgcatga ttcatcatcc ttgttcatat
    22021 tctctcttat tatctgttcc attataacgt aaaacatgcc atttttttct tttatttata
    22081 aaaatatttt acatgtatct atttgaattg gtcatctaat ttttagacaa acagtctaaa
    22141 tcgttgcctt tttttgtcag acatgtataa actataagcg aaagaggtgt tttaacatgg
    22201 atatatcagt gattgatgca acgaaaacaa atacacaaaa aggaatcctt tatggttcat
    22261 cgaatgctcc taaaaaaatg gtcgaattca tcaacttagc ttgtccgtat tgccgacaat
    22321 ggtttgaaga atcttatgag ctattagaag aagcagtcca aagcgggcaa ttgcagcgag
    22381 tgatcaaatt gttcgataaa gaaaaagaaa gcttacagcg agggaacgtg atgcaccggt
    22441 atctcacaat cagcgatggc caaaaagcga tcaaagagat caaacaaata ttcgatactc
    22501 aagacgagtg gaaacatctt tctctccaag aagtagcgga ttttgcagta gataaactaa
    22561 agctgacaga acaaaaagac gaacagctga gccaagctgt catcaacgaa gctgagcaag
    22621 cacatattcg atttgttcca actgtcatct tgggtaaaga aatctttgat gaatctattt
    22681 caatagagga attaaaagaa ttgatccaaa caaaataaaa aaataaggag cgtg
//
LOCUS       DAIGWC010000044        22582 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.045, whole genome shotgun sequence.
ACCESSION   DAIGWC010000044 DAIGWC010000000
VERSION     DAIGWC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22582
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.045"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            311..1090
                     /locus_tag="NOB74_001738"
     CDS             311..1090
                     /locus_tag="NOB74_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220926.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSYVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            1136..2080
                     /locus_tag="NOB74_001739"
     CDS             1136..2080
                     /locus_tag="NOB74_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI1220927.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVAIVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            2096..2875
                     /locus_tag="NOB74_001740"
     CDS             2096..2875
                     /locus_tag="NOB74_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HCI1220928.1"
                     /translation="MEETINLEEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            2887..3585
                     /locus_tag="NOB74_001741"
     CDS             2887..3585
                     /locus_tag="NOB74_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HCI1220929.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3613..4377
                     /locus_tag="NOB74_001742"
     CDS             3613..4377
                     /locus_tag="NOB74_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HCI1220930.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            4422..5111
                     /locus_tag="NOB74_001743"
     CDS             4422..5111
                     /locus_tag="NOB74_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI1220931.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            6338..7018
                     /locus_tag="NOB74_001744"
     CDS             6338..7018
                     /locus_tag="NOB74_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI1220932.1"
                     /translation="MIGIEEKKGVQKDVTIDREENLRGHRFYWIGRRAQDIFFSALAL
                     IALSPVMLITALAIVIDDPGGSPIFVQDRVGRNGKLFKFYKFRSMCVDAEAKLEALLA
                     QNEMDGPVFKIKDDPRITRVGKFIRKTSIDELPQLWNILKGDMSIIGPRPALPREVEQ
                     YGDYERQRLFVQPGLSCYWQIAPHRNELSFEEWVELDVKYINERSFITDWKIIFLTLQ
                     AVLFGYGE"
     gene            7047..8360
                     /locus_tag="NOB74_001745"
     CDS             7047..8360
                     /locus_tag="NOB74_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCI1220933.1"
                     /translation="MNIILLSGGSGRRLWPLSNDIRSKQFIKLFKDENGEYESMIQRV
                     YRQITTVDPDAKVTIATSKSQASAIHNQLGDKASICVEPCRRDTFPAILLAAAYLHDE
                     LGVGDDESVAVCPVDPYVDNSYYEGVEALEKLVQQNTANLTLMGIAPTYPSEKYGYII
                     PESSNEVSTVKEFKEKPDKATAEKYLAQNAVWNAGVFAFKLGYLLEKAHAMVDFEDYR
                     DLYSKYETLTKISFDYAVVEKETSIQVMRYNGDWKDVGTWNMMAEVMADNIKGKAVMD
                     DTCVNTQIVNELNIPILAMGCKDMVIAASGDGILISDKERSGYMKPYVEKISTEVMFA
                     EKSWGTYTVMDVQEGSMTVKVSMQAGQKLSYHYHNSRDEVWTVVAGQGKAIVDGMKQI
                     LRAGDVVTIAAGCKHTIEAVTNLDIIEVQIGETISVADKYKSSLN"
     gene            9166..9933
                     /locus_tag="NOB74_001746"
     CDS             9166..9933
                     /locus_tag="NOB74_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HCI1220934.1"
                     /translation="MGIEGGYLMSRMRFMNTEIDNLTMGEVLVEVEKMIQDRRCGYVV
                     TPNVDHIVQLETGKELQDVYKNASLILTDGKPLIWISKFYKTPIKEKISGSDIFSLLC
                     KMAAEKGYTMYFLGAAEGVAAKAADNLMKRFPGLNVVGTYSPPYGFEKDEDEMFKIDS
                     QIKRANPDMLIVGLGCPKQEKFMFYNCDRLGVPVSFGLGASLDFEAGNVKRAPKWMSD
                     YGFEWLFRITQDPKRMAKRYLVDDLKIFKLALKYRKK"
     gene            9960..10961
                     /locus_tag="NOB74_001747"
     CDS             9960..10961
                     /locus_tag="NOB74_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HCI1220935.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFRENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSTELSYSRTERVTNIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALKGKYADKKKLVDKAIYLERVLCNEAGGWQDQIAAAYGGFNRI
                     NFNSDGYEVLPIIITPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAVLTDKNRDLDDFGRLLDLTWRLKKATGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQNAVRSAMSNLMYIPFEFENGGTQVIHYTPEMYIPK"
     gene            10984..12270
                     /locus_tag="NOB74_001748"
     CDS             10984..12270
                     /locus_tag="NOB74_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HCI1220936.1"
                     /translation="MKVVIMAGGKGTRISSVASDIPKPMIKIENKPVLEHEIECLRDQ
                     GFTDIILTVSHLGDIIMNYFGDGSGISPVTGQPFDVKIEYFLEKEPLGNAGALFRLKD
                     NLTEDFLLLNADAMFDVDFNRFVAYHREKGGLVTLFTHPNSHPYDSGLIIADKDGSVD
                     RWLVKEDSRPTYYRNRVNAGLHVISPAVLDVEINTPKIDLDRQLLKPLAGTGKMFCYD
                     SPEYVKDMGTPDRYYAVCEDFKAGRVKGKNLQNKQKAVFLDRDGTINQYVGFLRHIDE
                     FELIKGTEDAVKKINAAGYLAIVITNQPVIARGEVSFEELEEIHNKMETLLGYKGAYL
                     DAVYYCPHHPHKGYEEERPELKFDCECRKPKPGMLIQAATDFNIDLSQSWMIGDGEND
                     IKAGQAAGCKTALVGESEYGQDMTIATLSEFADKIC"
     gene            12304..12957
                     /locus_tag="NOB74_001749"
     CDS             12304..12957
                     /locus_tag="NOB74_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1220937.1"
                     /translation="MIDNRLQKHIDLLIKRYPTLEVIKQDIVDGYLIMEECYLNDGKL
                     LIAGNGGSAADSEHIAGELMKSFKTPRPVSREFADKLIAVDPVKGSELAKNLEYGLMA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRPGDVFLGISTSGNSKNVINATVVARA
                     LGMKVIGLTGAKGGELARVADVCVKAPETETYMIQEYHLPIYHCWCLMLEDKFFGNR"
     gene            12990..14195
                     /locus_tag="NOB74_001750"
     CDS             12990..14195
                     /locus_tag="NOB74_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI1220938.1"
                     /translation="MNVLFITTQFPYPLDNGGKIGAYNGISVLSRDYDVTVLSFTEEP
                     QYVEEGVSFFREKFNSVKFENPVIHDVHIRNNPMKLVEALAIGYCLRQPYIVSKFYDS
                     KMLQLIDEKFSNNAYWDIIFIDYLNMQSYGQYIREKYKTQFGKYILKDHNIEYDLVLQ
                     EAESSRGLKKKLLQLEYKRTRKYEEAAVNRADYCFSVCDANTEVLKKINDNSYTMLPT
                     YEMLTGVKKNIEKNTILYLGNLSWKSNMQGLVWFLESIYPNIQQRIPDVKITIVGSGP
                     VGTDFSKYSGVDYRGYVKDISHIYDDQAVLIVPLLEGSGIRIKILEAFNNEIAVVSTL
                     VGCDTIGAKDGSELFIADNEKDFATAVVRLLEDMNLNEKVRKNAKLFLKEKYSLTARQ
                     DEFSAIINS"
     gene            14325..15650
                     /locus_tag="NOB74_001751"
     CDS             14325..15650
                     /locus_tag="NOB74_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220939.1"
                     /translation="MIVAAMSYHLTGNSNVASLIAVVGVVYAIVKACNNEYLAIWVMF
                     VLGSDIWGIVPYINIGSGVLHWSDFNVIVAIFLCLRFIKVKARSRYGIVYSVMLIFIL
                     IACVQSHSIYGQDVHTTLLTARELLVVISFWPIVKIVYSERITKNEFIDLVCKFTRWT
                     MCIYWFEWILVNMGFNITFLQTGARWGTRIYIDPIFIILYFFINLYAVIYKREGYNST
                     NKSIWNCIFSLLTFVIISQGRSGILYVVITSVIMLLISLKPSKIIRFGILGIALIACL
                     VSVTQIREVVISSFVESQSSDTGNIAYRIAEQDYFENKLEGHELFGVGIPNNHDARAV
                     EYSGKTIDFESKKYNPYYLEDLGAFEIRYRFGIIAYALYIVALAISIIDAGFRRDKSV
                     AAFAGMAFMVFMALNFNLLAYITARPFGFMISLILIEISAFNDEFIYIE"
     gene            15667..16797
                     /locus_tag="NOB74_001752"
     CDS             15667..16797
                     /locus_tag="NOB74_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220940.1"
                     /translation="MNLDRLKKIANMISPIIKVINAPLAYFSGKSDYMEKGILWPTVT
                     TYSNNSRKVIQYTTLPKNVDNMAQMQWAGESFEDICIVLQGPVLEDGDFTLNTVKMYN
                     KYYPKVKLVVSTWIGLSEETECKLREAGADVVLCKKPEKTGAYNINLQLTSAYEGVKM
                     AQKLGCSYALKTRTDQRLYANDVLKYFQTLLNIFPSSDCKVVNQRLIFTTYGKSFRYL
                     PFNLCDFLVYGETSELLKLYGIQRDNRASDFGKIIYTEEKEFNKKIFTLLEGKQGVSP
                     YDVFPDFDALYKKYMFAEYYIVYNYFLENIASNESYGDLMDAYYSYLKKYAVVADSEK
                     LLLYWPKYVQYNVKFENELDFYAKLDSKKWMDIYANYTPFSQ"
     gene            16823..17908
                     /locus_tag="NOB74_001753"
     CDS             16823..17908
                     /locus_tag="NOB74_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HCI1220941.1"
                     /translation="MKIGIVTIVNGASFGNRLQNYATQKVLENNGYTVETINNCFDKE
                     STLSIVIKNAIYTLFKFIPHFKKSKSIWKRMYTFYQWDKQYIDYSHRKIDASKKNSFV
                     SIKNDYDYFLVGSDQIWNPKYAANKGFELLSFVPNEKRVSLSTSLGVPSIPSDLEKLY
                     VTEWNKFKSISVRENQAAKIIEDLTGTTAAVHIDPTLMLERSEWEAFQKKPDNIDENY
                     ILSFFLTNPPKDTVDVLDKVAKDLKIGVLTLDASWEYFQDITPNHFVYLISHARMIYT
                     DSFHCTVFSLLFGKPVVVFDRFDSEKMNSRLSTLLNKVNKAHFWVGKKADEAMIRAIA
                     SEPEYDIDKLMVSERECVKAYLKEYLQ"
     gene            17931..18746
                     /locus_tag="NOB74_001754"
     CDS             17931..18746
                     /locus_tag="NOB74_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220942.1"
                     /translation="MEHLSDCFGKMKIVTTSCAREYFKDDLDKSEYSCFVDSRAAMFF
                     AMGQALAKRRNVVVMLADELTSCYTALTECAFQQVDLIVFAFQTVRHEIDLASLKNCG
                     CNLINCSAQDDIDRVVSNTKGLNQTTVIKINMNCESDKDHICEYIDLPDIPVFFHGSL
                     YSPASKKKYEQYGQVSKYLGYLVGGKDAILIISHNEFLNDISVWINYYSFGEIQPKII
                     IFDSPNDYQYKWLCDLECSVAHSTNRFLSEDLALLQNNGISIVLRGDNYDIVS"
     gene            18730..20448
                     /locus_tag="NOB74_001755"
     CDS             18730..20448
                     /locus_tag="NOB74_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylase"
                     /protein_id="HCI1220943.1"
                     /translation="MISSVKNVQILVSLLKQHNIKDIVISPGSRDFQLVHSVETDSFF
                     RTYTVVDERSAAFFANGLSMAIDKPVCVCCTSSTASSNYMAAAKDAFANGIQLVLLTA
                     DRDYRRLYQMEDQMIDQVDMYGAYVRSNVDIPIVKDSDDEWYATRKINEAILELNHGV
                     KGPVQINYQLMDLSAPFVETMPEYRKITRYQEDDLLSSVEIFKQKLLSKKRIMVLCGQ
                     QEENNLSALLEEFFIKYNTIIIKDNYSNIHGEHFIKTVLVTERMSVNAFIDYCPDLVI
                     TIGKHVWSFVKYTLRDKKLKFEHWRISEDGKIVDPFNKLTSVFQCSAEFFMETVTAGV
                     NSNNNLEYYNLWKTRLSKVCYPELVYSNFYAISELVKKIPDSALVHSSILNAARLYDF
                     VSDDKALLSFANLGADGIDGCLPTFLGQAEADKTRPAYLISGDLSFFYAMNSLCGDIP
                     DNAHIFLINNHSGSEFHTNFGKFYNGSLSVDKHIAAGHISNAKDWALENNIKYITADS
                     KESLKSGLDVFINTFDSPVLFEVFTDPDTDTSVLESFYSINKVITPKMYFRKALDIIK
                     KHLHIK"
     gene            20474..21310
                     /locus_tag="NOB74_001756"
     CDS             20474..21310
                     /locus_tag="NOB74_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1220944.1"
                     /translation="MAIKSYIKRLLLYIRHGDPKINLDVSYLSEGAMLAGKTVIITGG
                     AKGLGFAIAKSFIAQGASVIITGRDMDSLNNAKCQLGDMCSIRAFDITDAKMYRTFFE
                     DAYETFGRIDILLNNAGISLHEDGFMSVTEKTWDKQMDTNLKGVYFFTQEFIKFVKEK
                     NQMQANIIMMSSERGLCGDSIPYGLSKAAINSLVVGLSKKYISEGIRVNGIAPGVTAT
                     AMTGISEKGNLYNPATIGYRYFLPEEVAQVALFLASSLSNCISGEIIACDQGQYLSRN
                     WG"
     gene            21315..>22582
                     /locus_tag="NOB74_001757"
     CDS             21315..>22582
                     /locus_tag="NOB74_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HCI1220945.1"
                     /translation="MGILLKKYNSLSEPAKASIWFTLCNVLQKGILFLTTPIFTRMLS
                     TAEYGKYTIFISWYSIIAIFTTLNLSAGVYNKGLIKYENKYALTSSFLGLSSFISLCA
                     LMLYLPFRTVINGLLDLSTEFVILILIESIFEPAFLLWSVKERFDYKYQKLVLITVLM
                     AVLNPGLGIILILSFGEYAIWRVRAYVVVNVVVGMFIGIGILAKGKKLFDKEYWTYAL
                     RFNLPLIPHYLSMTLLNQVDRLMINSMVGASEAAIYSIAYTISSMMNIITTAINGSFI
                     PFTYKAIKDGVYEKIKSVANQLLVLIFVLCSFTMLFGPELIWVVGGEKYMDAVWIIPP
                     VAASVFFMFLYPLFGNIEFYYEKTNYVMFASCVGSIAKIISNYVSIPRFGYISAGYTT
                     LICYMLFSFAHYMFYKKILRENGIKEDMYN"
BASE COUNT         7510 a         3285 c         4882 g         6905 t
ORIGIN      
        1 tattattaat tcaatgttaa tttttttgtt attttatttt ttgtgtaact tttaaaaaca
       61 cctatgaaaa ttaaggaaat aaaaatgaaa tcgattaatt gttatcttat tactgtttta
      121 tttactttta aatcataaat tgccctagtc aagaaaacag tttgtggtat gattatatag
      181 ggaaaacttg tttacaaata tttctgtgaa tatattagtt taattatgtt ttttaaaata
      241 aaaagctgtc atttttatgt aagtgaatta tatcttaatt tatctatcat caatacttag
      301 gagtgaatct atggaaaagc cattcgtcaa gtcattgact gctgtggcgg taggtgcagg
      361 tgctattgcg atctgtttgt ttggttacca tatcaataat cagcggcaac atcagcaacg
      421 gatcaattat gcagaatctg ccatcaccaa tcaaaaagac accttgactt ctttatcaaa
      481 agaagtagac aagctgtata gtacaaaaga aaaaattttt ctaaaccctg aaataacaga
      541 agaaacaatc acaagtttgt caaataagct atcctatgtc aaactttcag cagatgatta
      601 cgacatcaaa gaatcagaat tgcctaaaga agctgttgca atccaagatg agaagaaagc
      661 aatcgtgaca cagttagata gtgcagaatc aaaactgaag atccagacag ctgtcaacga
      721 tttgtttact aaaaatgtat caaactggca gcaagctgta gacgatgtca tcatcaaaga
      781 aaaggtgaca agtgcagatg tcgctcgtgt acgtgaaaat atgagctttt ttaaagatag
      841 tccttggaaa acggttgtta tgcaatattt aggattcgct gatactcaga tcgcgcaagt
      901 cacgcaacta gatcagttat tcgatacgat gttgaaggat ggtcaagtga ctgccaccgc
      961 tacttacgat caatatttga cggcgctcag tcaaatagag cagatccgga atgaaaaaat
     1021 aagcgcagca tacgcaacaa aagcacaaac tgttgctcag caaatgggct atagcaatat
     1081 aagttattga cagttaaaac gttgattcaa gcaaggttag caaacggagg aaactatggc
     1141 aagacgaaga agaaaatcaa gagggaaaaa aatatttctg attattttag cagttcttat
     1201 cgtattagta ttagcaattg taggagtagg agcaaaatta tatctggatc tctcacattc
     1261 tattgagaaa acttacgaat cagtggaacg aacccaagga gaacgaacga aaccagttga
     1321 tctggacaaa caagaatctt tctctgttct attgatgggg attgatactg gagatttagg
     1381 tcgggtcgat caaggaagat cagatacgat gatggttgcc atagtcagtc ctgaagacaa
     1441 acagacaacg atcgtcagca ttcctcgtga tacgtatgtc gacatcgtag gtcgtgacac
     1501 aaaagacaag atcaaccacg cttacgcatt cggcggagct gccatggcga tggataccgt
     1561 acaaaaatat gtagacatcc caatcgatca ctatgtctct atcaatatga aagggctaaa
     1621 ggaacttgtt gatgcagttg gtggtatcga agtcaataat gacctcactt tctcacaaga
     1681 tggctatgac tttacaatcg gtaaaatcac attgaacggg gatcaggcat tatcttattc
     1741 tcgtatgcgt tatgaagatc caaatggtga ctatggtaga caagagcgtc aaagaaagat
     1801 cgtagaaggt gtagcaaaaa aagtattgag tttaaacggt gtcagcaact atcaatccgt
     1861 tttgaatgct ctagagtcga atatgaaaac agacatgagc tttgatgaaa tgaaaaaaat
     1921 cgctttagat tatcgggagg catttggtac gatcaagcaa gatcagctgc aaggagaagg
     1981 ctttatgcaa gataatatct cctatcaaaa agtcagtgat caagaacttg atcgtgtaaa
     2041 aaaagaatta aaagatcaaa tgaatctaga gaataaatag gaaagtggag aaaaaatgga
     2101 agagacaatc aacttggaag aaatttttga aacattacgc aaacacttgg taacaatcat
     2161 catctcaatg tttgctggct tggccatctc aggaatcgta acatttttca tcttgacacc
     2221 aaaatacagt tcacaagcac aattgatcgt gacactgcca caatcagaca cagcaaatgt
     2281 caatgatgtc aatacgaacc tgcaaatgat caatacgtat aaagatatga tcgtcagtga
     2341 tttagtacta aatgaagtca aagatcgttt agaaacagaa gacaatgtga aaatgactgc
     2401 tggacaaatc aaagatgcga tctccgtcaa tcagtcacaa aattcacaaa tgttctcgat
     2461 ccaggcaata agcacgaatg cagtgactgc tcaacagatc gctaacacaa cttcacaagt
     2521 tttccaagag aacgcaaaag acgtgatgaa tgtcgataaa atctcgatta tttcaggtgc
     2581 agttgccaat acgacacctg tttcgccaaa taataaattg aatctagtga ttggcttagt
     2641 attaggaatg atggtaggcg taggtctggc attcttattc gaattacttg atcggacagt
     2701 gaaagatgaa aaatatgtga cggatgcatt aggattccca atcttaggaa cagttccaga
     2761 aatgtcagcg aaagaattga acgctggtat ccgtaaaaaa ggaacagctc ctgcacgacc
     2821 aaaagctaca aacgataaaa cagccccatc acgcagaagc cgctcaagag tctaggagga
     2881 agaaaaatgg cacgaacaca gaaacaaaaa gcagcacaaa ctcatgcagt cagtttgatc
     2941 acattaacaa acccatcttc accaatcgcc gaacaatatc gtacgatccg gacgaatatc
     3001 cagtttgcct ccgcagctgg tcagcaaatc aaaacgattg tcgtgacttc atcaggtcct
     3061 ggagaaggaa aatccaccac tgcagcaaac attgcagtcg tttttgctaa atccggtcaa
     3121 cgagttctac tagtcgatgc agatttacgt aaacccgtcg tctataagac attccagctg
     3181 aacaatgcca ggggattaag tacagcactt agttcatcag gaagtgtagc agatgtaatc
     3241 caacgaacgc cagtcgagaa cttgtcgatt ttgcctagtg gacctaagcc acccaaccca
     3301 tcagaattgt taagttcgcc aagaatggat cagatcctag acgaagcaag acagttattt
     3361 gacgtggtga tattcgatat gccaccagta gtagccgtaa cagatgcaca gatcatgtct
     3421 tcaaaaacgg atggcacttt attggtcgta cgtgaaaata catcacgtaa agaatcattg
     3481 aataaagcaa aagaactgct agagatggta caagcacgag ttttaggtgt tgtatacaac
     3541 ggagcagaac atagcaaaga tgctggttat tactacggaa attaaggaat aagaagagag
     3601 gagacaagag aaatgatcga tctacattgc catatcctac caggaatcga tgacggggca
     3661 gaaaacttag aagcaagtat tgcaatggct gaaaaagcga ttcagcaagg catcacgcat
     3721 attttatgca caccacacca caataatgga aaatacagca atgaaaaatc acaagtcatt
     3781 tctctagtcg cttcgttaca agccgaatta gagaaaagac agttgccttt gacgttattg
     3841 gaaggacaag aagtacgtat taccggaacg ctcatcgaag acatccaccg agatgaaatt
     3901 ttatttacag atttagatga tacatatctt ctgatcgaat ttccgacact ggaagtgccg
     3961 ttatatgcag aatggctttt ttttgagttg ttagaactag gaaagacacc agtgatcgtc
     4021 catccagaac gcaacgcgca ttttcgagaa gacccaaatc atttgcttcc gttcctagat
     4081 atgggatgtt tggcccaaat tactgcgcca agttatgttg gtgtatttgg caaagacatt
     4141 cagaaaacag ccaaaacaat ggtcaaacat aatctcgtgc agatggctgc ttctgatgcc
     4201 catggggtct ctaagcgtac cttttactta aaagagtgct atgagcagat tgctaaggac
     4261 tttggtaagg aaaaagtagt acagatgaaa caagtcgcaa aggatctgat caacggggat
     4321 gaaatcagtt atccagtcta tgaagaggta aaaaagaaga agtttggttt attttagttc
     4381 tttattcgta gataaaaagg aaatgaggag agagggaaag tatggaaagt gaagatttat
     4441 tatctcgtat tagtgaagta catcctaatc aagtttggtt ggataaagaa aaagttgaaa
     4501 aacgatatat ctatttattt tttaaaagaa tgattgatat tgtaggaagc attattggtt
     4561 tgattttagc ttctcctttg atgttctatg tagcttatcg aatcagaaaa gaagagccag
     4621 gaagtccgat atttttttgc catacacgtg ttggtaaaaa tggaaaaaca ttcaaaatgt
     4681 ataaattccg ttcgatgtgt ttagatgctg aagaaaaatt ggaagaatta cttgatcaaa
     4741 atgaaataga aggtgcaatg ttcaagatga aagaagatcc ccgtgtcact aaaataggta
     4801 aaattatccg tgccaaaagc attgatgaat tgccacagct atggaatgtt ttaaaaggcg
     4861 atatgagtct aattggtcca cggccacctt tggagaggga agtagctgag tacacgagat
     4921 atgatcttca acgcttgtat gtaaaacctg gttgttcagg tttgtggcaa gttagtgata
     4981 gaaataatgt tagtttccat aaaatggttg agttggattt agagtatatt agtcatcgaa
     5041 gtttaatgta cgacttgagg ttgattttaa aaacgtttta tgttattgtc aagcccaatg
     5101 gagcatatta gttagggata gaatgatgga ttgttaataa aaaagattac acatgttcat
     5161 attatcgttt caaaagtaat aactgtaatt atggagggtt tgaatcactt gtagaaaatc
     5221 taaaaaaaga aaggtgaatg gggcaattca gtatcattat tcttatataa aagaaaatat
     5281 tcgaaatttt gggatgatac cactcttaaa tataatgatc taaatgcttt aatattggta
     5341 tatccgatat aggaactgac gagctattta gtatgataca aaagtatatt gatagccatt
     5401 aataaatttt ccaaaaaata atgacagcac accaattttt ataatttagc ttgttgaatc
     5461 ggtatgttca tgggacggtt caaaaaaaga atcgaaaaaa taaacggtaa aattttagtg
     5521 aatcctatgt aataaaattt ggatagatgg aaaaacagca cataaggagg ctgagtttgt
     5581 tgtcatttct gctcctacaa actatggtag tgaatgtgtt attgaattag tgatgtctgt
     5641 tacttcagag acattgggga taattaactt cactatacct gtagggtata caaaaaatgg
     5701 aagaaaaaat attatcaata gattttattt agttcagaat ttttacgtgg aagtaaatta
     5761 ttgatgataa tctttatcca attagaatta ttatcgtagg atgtgatgat gatagccgtg
     5821 aagttgttca agtatttacc aatgtctaca acgcagaaaa ttagtttggg tttttcggat
     5881 tggaaaattt caatgtataa aatcataaat ttgctgtaaa tagacagttt ggggtagtaa
     5941 tagcccaata aattgttcga taaactcatc tttggggtga gaatagctca atcattgaat
     6001 ttcaaacctg cctttggggt gggattagag gtcaatatgt acctacataa tactttttgg
     6061 aaaatgatgg tgttgagaat gtaagtacat ttcaatgtga aattctaata tagccccaaa
     6121 cgaggtcaat aaaaatgacc taaactcgta tttctcccct aaacgaggag gagatagata
     6181 tgaaaattga atgtgccggc gttggagttg gctgctttta gtaggaatga acatggttcg
     6241 atgagaactg tttcagatag agtggtcgat gatcacaggc ctttaagtcg tttacagatg
     6301 atgagacttg taaaaataga gggacgaatg gaaaaagatg attggtatag aagaaaagaa
     6361 aggtgttcag aaagacgtaa caattgatag ggaagagaat cttaggggac atagattcta
     6421 ttggattgga cgcagagcac aagatatctt cttctcggct ctagctttga ttgcattgag
     6481 ccctgtgatg ctaattacag cgctcgccat tgtgattgac gatcccggtg gcagcccgat
     6541 ttttgtgcag gatagagttg gaagaaatgg aaagctgttc aagttttata aattccgatc
     6601 tatgtgtgta gatgctgaag caaaattaga agccttgttg gcacaaaacg agatggatgg
     6661 tccggtcttc aagattaaag atgacccaag aatcacgaga gttggtaaat ttattcgaaa
     6721 gacaagtatc gatgagttac ctcagctctg gaacattctt aaaggtgata tgagtattat
     6781 tggacccaga cctgctttac cgagagaggt ggaacaatac ggtgactacg aaaggcagcg
     6841 gttgttcgta cagcctggtc ttagttgcta ttggcagatt gctccacatc gtaatgaact
     6901 gtcctttgaa gaatgggtgg aacttgatgt gaagtacatc aatgaaagaa gctttatcac
     6961 ggactggaag attatcttct tgactttaca ggctgtatta tttggatatg gtgaatgatt
     7021 atatatagta ttaggagttg aaatatgtga atattatttt attatcgggt ggtagcggta
     7081 ggcggttatg gccgctgtcc aacgatattc gtagcaaaca attcatcaaa ctgtttaagg
     7141 atgaaaatgg cgaatatgaa tctatgattc aaagagttta tcgccagatt acaactgttg
     7201 acccagatgc aaaggtcact attgcaacaa gtaagtctca ggctagtgca atccataatc
     7261 agttgggaga taaggcttcg atttgtgtag aaccttgtcg tagagatact ttccctgcaa
     7321 ttttgttagc tgcagcatat cttcacgatg aacttggcgt aggtgatgat gaaagtgttg
     7381 cggtttgtcc tgttgatcct tatgtagata attcctatta cgaaggcgtt gaagcccttg
     7441 agaagttggt gcagcagaat acggctaatt tgactttgat gggtattgca cctacatatc
     7501 ctagtgaaaa gtacggttat atcatccctg aaagttctaa cgaagtaagt actgttaagg
     7561 agtttaagga aaaacctgac aaagcaacgg cagagaaata tttagctcag aatgctgttt
     7621 ggaatgccgg tgtatttgcg ttcaaacttg gttacctgtt ggaaaaagct cacgcaatgg
     7681 tggattttga agattatcgt gatttgtatt ccaagtatga gactttaacc aagatcagct
     7741 ttgactatgc tgtggtcgaa aaagaaacga gcattcaagt gatgcgttat aacggggatt
     7801 ggaaagatgt cggaacttgg aacatgatgg ctgaagttat ggctgataat attaagggga
     7861 aagctgtaat ggatgatacc tgtgttaata ctcagattgt gaatgagttg aatattccta
     7921 ttcttgctat gggctgcaaa gatatggtaa ttgcagcaag tggcgatgga attctgattt
     7981 ctgataaaga gcgcagtggc tatatgaagc cgtatgttga gaaaatcagt acggaagtaa
     8041 tgtttgcaga aaaatcctgg ggtacatata ccgttatgga cgttcaggaa ggctccatga
     8101 ctgttaaagt ttctatgcag gccggacaga agttgagcta ccactaccac aattctcgcg
     8161 atgaagtttg gactgttgta gcaggacagg gtaaagcgat tgtagatggt atgaagcaga
     8221 ttcttcgtgc gggtgatgtg gtgactattg ccgcaggatg taaacataca atcgaagccg
     8281 tgacaaatct ggatattatc gaagttcaga ttggtgaaac tattagcgtc gctgacaagt
     8341 ataagagttc tttgaactaa aagttcgcga ggtagttatt atggagatac taaaatttca
     8401 acccgtgggt aaagattatc tttggggtgg agaacggttt aagacggaat ttggaaaaaa
     8461 ttgacttaac accattaagc ttatacgtgg gaatgcttag ttcatctaga cgataactac
     8521 gtacggaaat atcaaatatg aaggacagaa tggtaaaacc gagttgtggt atgtattgga
     8581 agctacaccg gggggtgatt tatgcttttg agtacgatgt aacagaagaa atgttacgaa
     8641 atgctgtgat ggacagatca cttgggaaac atttatataa agaagaagta cacaagggag
     8701 atctttttta tgtcagttca tggtattggc gctggagtat tagtggctga aatacaggaa
     8761 agctcaaatg ttacctatcg agtttacgat tatgatcgag tagataagaa tgataataag
     8821 tgagaattgt actttgaaaa agcgattcag gtaatgaata tggaagccac tttgaaattg
     8881 gagaaaagaa ataagctcat tcatttttat cctggtggct ctcgtgaaat actgtgtaga
     8941 tgtaaatact gtgagcccga aagaatccaa gtaaagacgg ggttttcgtt ctcggtaaaa
     9001 gaggaatctt ttcaagttct tttatgtata tcgggggacg gacaagttga gtcggcaaat
     9061 ggtgttatga aactcattag atttgtaaaa aagatattgt atgtttttgc caacgaatat
     9121 tggaagatgt taagtgttga gcgatgcgga cttactgaaa attagatggg gatagaggga
     9181 ggatatctaa tgtcacgaat gagatttatg aacacagaaa ttgacaatct tacaatgggt
     9241 gaagtattgg tagaggttga aaaaatgatt caagatagga gatgcggata tgttgtaact
     9301 ccgaatgtgg atcacattgt tcagttggaa acaggaaaag agttgcaaga tgtttataaa
     9361 aacgcatctt taattttgac ggatggtaaa ccattgattt ggatttcaaa gttttataag
     9421 acaccaataa aagaaaaaat atcgggatcc gatatatttt ctttactgtg caagatggct
     9481 gcagaaaagg gatacacaat gtatttttta ggtgcggcag agggcgttgc ggctaaagcg
     9541 gcagataacc tgatgaaaag atttccggga ttaaatgttg taggaacata ctctcctcct
     9601 tatgggttcg aaaaagacga agatgaaatg tttaaaattg attcccaaat taaacgagca
     9661 aatccagata tgcttattgt gggtttgggt tgccctaaac aggaaaaatt tatgttttat
     9721 aactgtgata gattgggagt acctgtgtct tttggtctag gagctagttt ggactttgag
     9781 gcagggaatg ttaaaagagc accaaaatgg atgtcagatt atggatttga gtggctgttt
     9841 agaattactc aggaccctaa aagaatggca aaacgatatt tggttgatga tttaaaaatc
     9901 tttaaattag cactaaaata tcggaaaaaa taaactatat tcaatgagga caatgaagta
     9961 tgattattac aaaaacacct tttcgcatgt ctttttttgg cggcggaacg gatatggaag
    10021 attattttcg agaaaatggc ggtgcagtgc tttccactac ttttgataag tactgttatg
    10081 tgaatgtgcg tcatttgcct agattttttg attacagcac agagttatca tattctcgta
    10141 ctgagagagt aacaaatatt gaagatatcg agcatcctgc aattcgtaat gcgatgaaaa
    10201 tgctagatat gcatgaaatt cgccttacat atgaagcaga tcttcctgca cgttctggtc
    10261 tgggtacatc tagttctttt gccgtaggta tgttgaatgc tttctatgct ttgaagggca
    10321 agtacgctga caagaagaaa ctcgttgata aagcaattta tcttgaaaga gtcctttgta
    10381 atgaagcagg cggatggcaa gatcagattg cagcagctta tggtggcttt aaccgaatca
    10441 atttcaactc agatggctat gaagtattgc ctattattat tacgcctgag cgtaaaaagc
    10501 agcttaacaa caacttgatg atgttcttta ctggattcac cagattttcc tctgatgttc
    10561 agaaggcaaa taatgtcagc ggcacagagg acaaaagagt aagactgaaa aaaatgtatg
    10621 agcttgtgga tgaagcagaa gcggttctga ctgataagaa cagagatcta gatgatttcg
    10681 gcagactgct tgatctcact tggagattga aaaaggctac cggtggtgcg attagcactg
    10741 gaagtatcga tgaactttat gaaaagggca tggctgctgg tgcattgggc ggtaaacttc
    10801 tcggagcagg tggcggcggt ttcttggttt tttatgttca gcctgaaaaa caaaatgctg
    10861 tgcgttcggc aatgagtaat ttgatgtata ttccgtttga atttgaaaac ggtggaacac
    10921 aggttattca ttacacaccg gaaatgtata ttccaaaata aagaaatcag cgaggataag
    10981 aatatgaaag ttgttattat ggcaggcggt aagggaactc gcatctcatc ggttgcaagc
    11041 gatattccaa agcccatgat taaaattgaa aacaaaccgg tattggagca cgaaatcgaa
    11101 tgtctgagag accagggatt cacagatatt attcttaccg ttagccatct tggcgatatc
    11161 attatgaact attttggcga tggttctgga atttcaccag ttactggtca gccctttgac
    11221 gttaaaattg aatacttttt ggagaaagag ccattaggaa atgccggtgc attgtttcgt
    11281 ttaaaggata atttgaccga agacttcctc ctgctgaatg cagatgcgat gtttgacgtt
    11341 gatttcaacc gatttgtagc atatcaccgt gaaaagggtg gcttggtgac attgtttact
    11401 caccctaaca gtcatccata tgacagcggt ctaatcattg cagataagga tggctctgta
    11461 gacagatggc ttgtaaagga agattcccgt ccaacttatt accgtaacag agtaaatgcg
    11521 ggactccatg tgattagtcc tgctgttctt gatgtcgaga taaacacacc taagattgac
    11581 ttggaccgtc agttattaaa gccgttggca ggaaccggaa aaatgttctg ctatgatagt
    11641 ccagaatacg taaaagacat gggtacccct gatcgttatt atgctgtctg tgaagatttt
    11701 aaggctggaa gagtgaaggg caaaaatctt cagaataagc agaaagctgt tttccttgat
    11761 cgtgatggaa cgattaatca atatgttggc tttctgcgtc atattgatga gttcgaacta
    11821 atcaagggta ctgaagatgc agtgaaaaag atcaatgccg ctggatatct ggctattgta
    11881 ataacgaatc agccagtaat tgcaagaggt gaagtttctt ttgaagaatt ggaagagatc
    11941 cataacaaaa tggagacact tcttggatat aagggcgctt atttggatgc agtttattat
    12001 tgcccgcatc atccacataa gggatatgag gaagagcgcc cagagctaaa attcgattgt
    12061 gaatgcagaa agccaaagcc cggaatgtta attcaggcag ctacggactt caacatagat
    12121 ttgagtcagt cttggatgat tggcgatggc gagaatgata ttaaagcggg ccaagccgcc
    12181 ggctgtaaga ctgcattggt tggcgagagt gagtatggac aggatatgac catagcaacc
    12241 ctgagtgaat ttgcagataa gatctgctaa gggatgtttt atcacgaaag gagagtataa
    12301 acaatgatag acaatagatt acagaaacac attgatttgc tgattaaacg ctatcccact
    12361 cttgaagtaa tcaagcagga tattgttgac ggatacctga ttatggagga atgctattta
    12421 aatgatggca agctgctgat agcaggaaat ggcggatctg ctgctgattc cgagcatatt
    12481 gcgggtgagc tgatgaaaag ctttaagacg cctcgccctg ttagtaggga atttgcagat
    12541 aaattgattg cggttgatcc tgtaaagggt tctgaattag ctaagaatct tgaatatggt
    12601 ttgatggcga ttcctctcgt tgctcatgaa gcgctttcca ctgcgtatat taatgatgtt
    12661 gatggcctag gtgttttcgc acagcagttg tttggatttg gaagacctgg cgatgtattc
    12721 cttggtattt cgacatccgg caatagcaaa aatgtgataa atgcaactgt tgttgctaga
    12781 gctcttggta tgaaagtaat tggcttaact ggagccaaag gtggagaact tgcaagggta
    12841 gcagatgttt gtgttaaagc tcctgaaaca gaaacatata tgattcagga gtaccatttg
    12901 ccaatttacc actgttggtg tctaatgttg gaagataaat tttttgggaa tagataaaat
    12961 atctaagccc atattgaaag gataaaatta tgaatgtact atttataaca actcaatttc
    13021 catatcctct agataatggc ggaaaaattg gtgcgtacaa cggtatcagt gttttatcta
    13081 gagactacga tgtgacggta ttgtctttca ccgaagaacc gcagtatgtt gaagaaggtg
    13141 tcagtttttt tcgagagaaa tttaatagtg taaaatttga aaatcctgtg atacatgatg
    13201 tacacataag aaataatcca atgaaattgg tagaagcttt agcaataggg tattgtctac
    13261 gccaacctta tatagtttca aagttttatg attcaaaaat gctgcagtta atagatgaaa
    13321 aattttctaa caatgcatat tgggatatca tttttattga ctatctgaat atgcaaagtt
    13381 atggtcaata catacgggag aagtataaaa cacaatttgg taagtatatc ttaaaagacc
    13441 acaacataga atatgattta gtcctacagg aagctgaatc aagtcgaggt ttaaaaaaga
    13501 agttgcttca gttagagtat aagcgtactc gaaagtatga agaggccgca gtaaataggg
    13561 ccgattattg ctttagtgtg tgtgatgcaa atacggaagt actgaaaaag attaatgaca
    13621 acagttatac gatgcttcca acttatgaaa tgcttacagg ggtgaaaaaa aatatagaga
    13681 agaacacgat cctatatttg ggtaaccttt cttggaaatc caatatgcaa ggattagttt
    13741 ggtttttaga gtcaatttat ccaaatattc aacaaagaat tccggatgta aaaatcacaa
    13801 ttgtcggtag cgggccagtt ggaacagatt ttagtaaata ttcaggcgtg gattatcgtg
    13861 ggtatgtaaa agatatttca cacatttatg acgatcaagc ggtgctaatt gtacctttgt
    13921 tagaaggtag tggtataaga ataaaaatat tagaagcgtt caataatgaa attgcagttg
    13981 tatctacatt agttgggtgt gatacgattg gcgcaaaaga tggaagtgag ttatttatag
    14041 cagataacga aaaagatttt gcaacggctg tagttagact gcttgaagac atgaatttga
    14101 atgaaaaagt aagaaagaat gcaaaattat tcttaaaaga aaaatactcc ttaacggcta
    14161 gacaagatga gtttagtgcg ataattaaca gctaatatat atataagctt atctgatgat
    14221 gatttatagg aggaaatata tggagatggc tgagagaaag gaaaagaaac ttggaaataa
    14281 gaatatcata ttattttaga aaactcctgt tattttatgt ttgtgtgatt gttgcggcta
    14341 tgagttacca ccttacaggc aattccaatg tagcgtcatt aattgctgta gtaggagtag
    14401 tttatgctat tgtaaaggcg tgtaataacg agtatctggc tatatgggtt atgtttgtat
    14461 taggttctga tatatggggg atagtgccat atattaacat tggtagtggt gtgttgcatt
    14521 ggtcagattt taatgttata gtagcgatat ttctctgctt gagattcatc aaagttaaag
    14581 ctaggagtag atacgggatt gtctatagtg taatgcttat atttattttg attgcatgtg
    14641 tgcaatcgca ttcaatctat ggacaagatg tacatacaac gctcttaaca gctagagaat
    14701 tgctagttgt aatatccttt tggccgatag taaaaatagt atattcagaa agaataacta
    14761 aaaatgaatt cattgattta gtgtgtaaat tcacaagatg gacaatgtgt atatattggt
    14821 ttgaatggat tcttgttaat atgggattca atataacctt tttacagaca ggtgcacgct
    14881 ggggtactag aatctatata gatccgatat ttatcatttt atatttcttt ataaatctat
    14941 atgcggttat atataaaaga gagggctata atagtacaaa taaaagtata tggaattgca
    15001 tttttagttt actgacattt gttataatct cgcaaggcag aagtggtata ttatatgtag
    15061 taataacctc ggttattatg cttttaattt cgcttaaacc atccaagatt attagatttg
    15121 gtatattagg aattgcctta attgcatgtc tagtgtctgt gacccaaatt agagaggtcg
    15181 ttatatcttc gtttgtagag tctcagagca gtgacacagg taatatcgca tatagaattg
    15241 ctgaacaaga ttattttgaa aataaattag aaggtcatga actatttgga gttggtatac
    15301 caaacaatca tgatgccaga gctgtagaat attcaggcaa aacaatagat tttgagtcta
    15361 aaaaatataa tccctattat cttgaggact taggcgcttt tgaaattcgt tatagatttg
    15421 gtataattgc atatgcgtta tatatagttg ctttagctat aagtattata gatgccggat
    15481 ttcgaagaga caaatcggtc gccgcatttg cgggtatggc attcatggtg tttatggcgc
    15541 ttaattttaa tttgctagcg tatattacag caagaccgtt cggatttatg atttctttaa
    15601 ttttgataga aatatcggca ttcaatgatg aattcatata tattgaatag gtaagggaga
    15661 gcacagatga atttagatcg attaaagaaa atagcaaata tgatttcacc aatcataaaa
    15721 gtgataaatg cgccgttagc gtattttagt gggaaatcag attatatgga gaagggaata
    15781 ttgtggccta ctgtaacaac ctactccaat aacagtagaa aagtgattca atatacaact
    15841 ttacctaaaa acgtagacaa catggctcaa atgcaatggg ctggggaaag ttttgaggac
    15901 atatgtatag ttcttcaagg tccagtatta gaagacggtg attttacact aaataccgtt
    15961 aaaatgtata ataaatacta tcctaaagta aaacttgtag tgtctacttg gataggatta
    16021 tctgaagaga cagaatgcaa gttgcgtgaa gctggtgcag atgttgtatt atgcaagaaa
    16081 cctgaaaaaa caggtgcgta caatattaat ctacaactta cttctgcata cgaaggcgta
    16141 aaaatggcgc aaaaactggg gtgtagttat gcgctgaaaa cgcgaactga tcaaagacta
    16201 tatgcaaatg atgtactaaa gtatttccaa acattattga atatttttcc atcttcggac
    16261 tgtaaagtag tgaatcagcg attaatattt acgacttatg gaaaatcatt tagatatctt
    16321 ccgtttaatt tatgtgattt tttggtatac ggagaaacta gtgaattatt aaaattatat
    16381 ggtattcaaa gagataaccg agcatcagac tttgggaaaa ttatttatac tgaggaaaaa
    16441 gagtttaata aaaagatatt tacactacta gaaggaaaac aaggtgtatc tccatatgat
    16501 gtttttccag attttgatgc actatataaa aaatatatgt ttgcagaata ctatattgtg
    16561 tataattatt tcctggaaaa tattgcaagt aatgaatctt atggtgactt aatggatgcc
    16621 tattatagtt atttaaagaa atatgcagtt gttgctgatt cagaaaaatt gttactatat
    16681 tggccgaaat atgttcaata taatgttaag ttcgaaaatg aacttgattt ctatgcgaag
    16741 ttggattcaa aaaaatggat ggatatttat gctaattata caccttttag tcagtgatta
    16801 tatggaaagg atgaggtgaa taatgaaaat cggaatagtg actattgtta atggggcaag
    16861 ttttggtaac agattacaaa attatgcgac tcaaaaagtg ttggaaaata acggctatac
    16921 agttgagaca attaataatt gttttgacaa agaaagtacc ctatccattg ttatcaaaaa
    16981 cgctatttat acattattta agtttatacc gcatttcaaa aagtcaaaaa gtatctggaa
    17041 aagaatgtat acattttatc aatgggacaa gcagtatata gattattctc atcgtaaaat
    17101 tgatgcatct aaaaaaaaca gctttgtgag tataaagaat gattatgact atttcttggt
    17161 tggtagcgat caaatttgga atccaaaata tgcagccaat aagggatttg aacttttatc
    17221 atttgttcca aatgaaaaaa gagtttcatt atcaaccagt ttgggagttc catctatacc
    17281 aagtgattta gaaaaattat atgtgacaga gtggaataag tttaaatcaa tatcggtacg
    17341 tgaaaatcaa gcggcaaaaa taattgagga cttgacaggc acaactgcgg ctgttcacat
    17401 tgacccaact ttaatgttgg agcgttcgga atgggaagcc tttcaaaaaa aaccagacaa
    17461 tattgatgaa aattacatct tgtcgttttt cttaactaat ccgcctaagg atactgttga
    17521 tgtattagat aaggtcgcta aagatttgaa aataggtgtt ctcaccttag atgcgtcttg
    17581 ggaatatttt caagatatta ctccgaatca ttttgtttat ttgatttcac atgcaagaat
    17641 gatttataca gattcattcc actgcacagt tttttcattg ctatttggaa aaccggttgt
    17701 ggtatttgac cgttttgata gtgaaaaaat gaattctagg ttaagtacat tgttaaataa
    17761 agtaaataaa gcacattttt gggtaggaaa aaaagctgat gaagcaatga ttcgtgcaat
    17821 agcatctgaa cctgaatatg acatagataa gctgatggta tcagagaggg aatgtgtaaa
    17881 agcttatctt aaagagtatt tacagtaaaa ttttgaaatg ggatgaaaat atggagcatt
    17941 taagtgattg ttttggtaaa atgaagattg ttacgacttc atgcgcaaga gaatatttta
    18001 aggatgattt ggataaatca gagtattcat gttttgttga ttctcgagca gctatgtttt
    18061 tcgcaatggg acaagcttta gctaaaagaa ggaatgtagt tgtaatgctt gctgatgaat
    18121 tgacatcgtg ttatacggca ctaacagaat gtgcatttca acaagttgat ttaattgtgt
    18181 ttgcttttca gacagtcaga catgaaattg atttagcatc tttgaagaat tgtggttgca
    18241 atctaattaa ctgtagcgcc caagacgata ttgatagagt tgtgtccaac actaaggggt
    18301 taaatcagac aacagtaatt aaaatcaata tgaattgtga gtcggataaa gatcatatat
    18361 gtgagtatat agacctgcca gacatacctg tttttttcca cggtagctta tactcacctg
    18421 caagtaaaaa gaaatatgag cagtatggac aggtatcgaa gtatttaggc tatctcgtgg
    18481 ggggaaaaga tgcaatactc ataatttctc acaatgagtt tttaaacgat atcagtgtat
    18541 ggattaatta ttattctttt ggagaaattc aacccaaaat tattatattt gacagtccga
    18601 atgactatca atataaatgg ctgtgtgact tagaatgcag tgtagctcat tcaaccaacc
    18661 gatttttgtc tgaggattta gccttattgc aaaataacgg aatttccatt gtgttaagag
    18721 gtgataatta tgatatcgtc agttaaaaat gttcaaattt tagtatcttt attaaaacag
    18781 cataatatta aagatatagt tatctcgcca ggtagtagag attttcaatt ggtgcatagt
    18841 gtagaaacag acagtttttt tagaacctat acggttgtag atgagcgcag tgctgccttt
    18901 tttgctaatg gactttctat ggcgattgat aagcccgtgt gtgtatgttg tacttcttca
    18961 actgcctctt caaattatat ggcggcagct aaagatgctt ttgctaatgg catccaactt
    19021 gtacttctta ctgctgatag agattaccgc cgcttatatc agatggaaga tcagatgatt
    19081 gatcaggtag atatgtatgg ggcttatgtg cgttctaacg ttgatattcc tattgttaag
    19141 gattctgatg atgaatggta tgctaccaga aaaataaatg aagcaatatt ggagttaaat
    19201 catggcgtta agggtcccgt gcagattaat tatcaattaa tggatttaag tgcgccgttt
    19261 gttgagacca tgccagagta tcgtaaaatt acaagatatc aagaggatga tttactgtca
    19321 tcagtagaga tttttaaaca gaaactatta tcaaaaaaga gaataatggt tttatgtgga
    19381 cagcaggaag aaaataattt aagtgcctta ttggaagagt tctttattaa atataataca
    19441 attataatca aggataacta ttctaatata cacggtgaac actttattaa gactgttcta
    19501 gtaacagaaa gaatgagtgt aaatgcattt attgattatt gcccagattt ggtaataact
    19561 attggtaaac atgtatggtc ttttgtgaaa tatactctta gagataaaaa gcttaaattt
    19621 gagcattggc ggatatctga ggatggtaag attgttgatc cgttcaacaa gctaacatct
    19681 gtctttcagt gctcagcgga attttttatg gagactgtca ctgctggtgt gaatagcaat
    19741 aataatcttg agtattataa tctatggaag acaagattat caaaagtttg ctatccagag
    19801 ttagtctata gcaattttta tgcaatttca gaactagtaa aaaaaattcc agatagtgca
    19861 ttagttcatt ctagtatttt aaatgcggct agattgtatg actttgtatc tgatgataaa
    19921 gcattactca gttttgctaa tttaggggct gatggtattg atggttgttt accaacattt
    19981 ttaggtcagg cagaagcaga taaaactcga cctgcgtatt taatttcagg agacttgagt
    20041 ttcttttatg ctatgaatag tttatgtggt gacattccag ataatgcaca tattttcctt
    20101 attaacaatc attctggaag tgaattccat acaaattttg gtaagtttta caacggatca
    20161 ttaagtgttg ataagcatat agctgcagga catatttcaa acgcaaagga ttgggcatta
    20221 gaaaataata taaaatacat tactgcggat tctaaggaaa gtctcaaatc ggggttggat
    20281 gtatttatta atacatttga cagtcctgtt ttatttgagg tctttacaga tccggatacg
    20341 gatacgtctg ttctggaatc tttttatagt ataaataagg taatcacacc aaaaatgtat
    20401 tttagaaagg cgttagatat tataaaaaag catttacaca ttaagtagat gtttattgcg
    20461 aggtgaaaca aatatggcaa taaaatctta tattaaacgg ttattgcttt atatccgtca
    20521 tggagatccc aaaataaatt tagatgtgag ttatttatct gaaggtgcaa tgcttgctgg
    20581 taagactgtg ataattacgg gtggtgcaaa aggacttggt tttgcaattg caaaatcatt
    20641 tatagctcaa ggcgcaagcg ttattattac aggaagagac atggattcgt tgaataatgc
    20701 taaatgtcag cttggagata tgtgttctat cagggcgttt gatataactg atgctaaaat
    20761 gtatcgaacg ttttttgaag atgcatacga gacctttgga cgtattgata tactgcttaa
    20821 taatgctggg atctcgttac acgaagatgg atttatgagt gttactgaga aaacttggga
    20881 taagcaaatg gatacaaatt tgaaaggtgt ttatttcttt acacaggaat ttattaagtt
    20941 tgttaaagaa aagaatcaaa tgcaagcaaa tattattatg atgtcctcag aaagaggctt
    21001 gtgtggtgat agtattccgt atggattatc aaaggctgca attaactctt tagttgtagg
    21061 cttgtctaag aaatatattt ctgagggaat tagggttaat ggtattgctc ctggagtaac
    21121 tgcaaccgct atgactggta tttctgaaaa gggtaatttg tataatcctg caacgatcgg
    21181 ttatagatat tttctcccag aagaagttgc tcaagttgct ttgtttttgg caagtagtct
    21241 ttcaaactgt atcagtggtg aaatcatagc ctgtgaccag gggcaatatt taagtcgaaa
    21301 ttgggggtaa taacttggga atattattaa aaaaatataa tagccttagt gagcctgcaa
    21361 aagcatctat ttggtttaca ctttgtaatg tgttgcaaaa aggaattcta tttttgacta
    21421 cacctatttt tacaagaatg ctttcaactg cagaatatgg taagtatacg atttttatat
    21481 cgtggtattc tattatagca attttcacaa cgttgaattt atctgcaggt gtctataata
    21541 aaggactaat taaatacgag aataaatatg cattaacctc gtcattttta ggattatcgt
    21601 catttatttc cctttgtgca ttgatgctat accttccatt tagaacggtt ataaatgggc
    21661 tactggattt atcgacggag tttgtcatat tgattcttat tgaatcaata tttgagccgg
    21721 cttttttgct ttggtcagtt aaggaacgat ttgattacaa gtatcaaaaa ctagtactca
    21781 tcacagttct tatggctgtt ttaaatccag gtctcggtat tatattaatc ttatcatttg
    21841 gggagtatgc tatttggaga gtacgagctt atgtcgtggt aaatgttgta gtggggatgt
    21901 ttattggcat aggaatactg gctaagggta agaaattatt tgataaagag tactggacat
    21961 atgcgctcag atttaatttg ccattaatac cacattattt atcaatgaca ttgctgaatc
    22021 aggttgatcg ccttatgata aatagtatgg ttggagctag cgaggctgcg atttatagta
    22081 tcgcttacac tatatctagt atgatgaata tcataacaac agctataaac ggttctttta
    22141 ttccttttac atacaaagca attaaagatg gcgtgtatga aaaaattaaa tccgttgcta
    22201 atcaactatt agtgttgatt tttgtcttgt gttcgtttac tatgctgttc gggccagaat
    22261 tgatttgggt tgtcggagga gaaaaatata tggatgctgt ttggattatt cctccagttg
    22321 cggcatcagt atttttcatg tttttatatc cgctttttgg caatattgaa ttttactatg
    22381 aaaagacaaa ctacgtaatg tttgcatctt gtgtgggctc tatcgcaaaa attatttcaa
    22441 actatgttag tattccccgt tttggatata tttcggctgg ttacacgaca ttgatttgct
    22501 atatgttgtt ttcctttgcc cactacatgt tttataaaaa aattcttaga gaaaatggta
    22561 taaaagaaga tatgtataat at
//
LOCUS       DAIGWC010000045        22357 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.046, whole genome shotgun sequence.
ACCESSION   DAIGWC010000045 DAIGWC010000000
VERSION     DAIGWC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.046"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            61..459
                     /locus_tag="NOB74_001758"
     CDS             61..459
                     /locus_tag="NOB74_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCI1220946.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            443..1138
                     /locus_tag="NOB74_001759"
     CDS             443..1138
                     /locus_tag="NOB74_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HCI1220947.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1732..2619)
                     /locus_tag="NOB74_001760"
     CDS             complement(1732..2619)
                     /locus_tag="NOB74_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCI1220948.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2804..3643
                     /locus_tag="NOB74_001761"
     CDS             2804..3643
                     /locus_tag="NOB74_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI1220949.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3839..4813
                     /gene="sgrA"
                     /locus_tag="NOB74_001762"
     CDS             3839..4813
                     /gene="sgrA"
                     /locus_tag="NOB74_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HCI1220950.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5111..5467
                     /locus_tag="NOB74_001763"
     CDS             5111..5467
                     /locus_tag="NOB74_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220951.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5470..6627
                     /locus_tag="NOB74_001764"
     CDS             5470..6627
                     /locus_tag="NOB74_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1220952.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6653..7093)
                     /locus_tag="NOB74_001765"
     CDS             complement(6653..7093)
                     /locus_tag="NOB74_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCI1220953.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7253..7759
                     /locus_tag="NOB74_001766"
     CDS             7253..7759
                     /locus_tag="NOB74_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI1220954.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7927..9840
                     /locus_tag="NOB74_001767"
     CDS             7927..9840
                     /locus_tag="NOB74_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HCI1220955.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9845..10846
                     /locus_tag="NOB74_001768"
     CDS             9845..10846
                     /locus_tag="NOB74_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1220956.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11048..11254)
                     /locus_tag="NOB74_001769"
     CDS             complement(11048..11254)
                     /locus_tag="NOB74_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HCI1220957.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11900..12748)
                     /locus_tag="NOB74_001770"
     CDS             complement(11900..12748)
                     /locus_tag="NOB74_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI1220958.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12747..13814
                     /gene="gnd"
                     /locus_tag="NOB74_001771"
     CDS             12747..13814
                     /gene="gnd"
                     /locus_tag="NOB74_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HCI1220959.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13816..14817
                     /locus_tag="NOB74_001772"
     CDS             13816..14817
                     /locus_tag="NOB74_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HCI1220960.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14814..15098
                     /locus_tag="NOB74_001773"
     CDS             14814..15098
                     /locus_tag="NOB74_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HCI1220961.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15131..15928
                     /locus_tag="NOB74_001774"
     CDS             15131..15928
                     /locus_tag="NOB74_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI1220962.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15942..16775
                     /locus_tag="NOB74_001775"
     CDS             15942..16775
                     /locus_tag="NOB74_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1220963.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16793..17650
                     /locus_tag="NOB74_001776"
     CDS             16793..17650
                     /locus_tag="NOB74_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI1220964.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17672..18181
                     /locus_tag="NOB74_001777"
     CDS             17672..18181
                     /locus_tag="NOB74_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1220965.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18218..18619
                     /locus_tag="NOB74_001778"
     CDS             18218..18619
                     /locus_tag="NOB74_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220966.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18731..19084
                     /locus_tag="NOB74_001779"
     CDS             18731..19084
                     /locus_tag="NOB74_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220967.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19118..19561
                     /locus_tag="NOB74_001780"
     CDS             19118..19561
                     /locus_tag="NOB74_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI1220968.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19578..20663
                     /gene="uxuA"
                     /locus_tag="NOB74_001781"
     CDS             19578..20663
                     /gene="uxuA"
                     /locus_tag="NOB74_001781"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCI1220969.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20656..21369
                     /locus_tag="NOB74_001782"
     CDS             20656..21369
                     /locus_tag="NOB74_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI1220970.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21576..21725)
                     /locus_tag="NOB74_001783"
     CDS             complement(21576..21725)
                     /locus_tag="NOB74_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1220971.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22121..22321
                     /locus_tag="NOB74_001784"
     CDS             22121..22321
                     /locus_tag="NOB74_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI1220972.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7706 a         3434 c         4629 g         6588 t
ORIGIN      
        1 tctagaaaca ttttgaataa aaactattag acaaatgata ttttacgagg aggaacagag
       61 atgacgatct ttgaaacggt tgtaacagat gttggtatag aagcagaagt attcaggaaa
      121 gaaaaaataa tgattttatt tggagatgaa gcaccggaaa cattaacaga ttattgttat
      181 aagattgaat tgaatcaggt aagaaaagaa ataacttgtg atatgaagct ctgttttgat
      241 aaacaaatgt atgtaatcac agcagtagga gatgttgtcc aaactaattt gaatgaatta
      301 ggacatatca cgataaaatt tgatggatct catgagccgg aacttccagg aacaatgtat
      361 gtagaagata aggaaatgcc gcatttaaga aaggggacaa tcattaaaat cgatcaagag
      421 gatcagaatg ggggaaagct atatggaaat catgcttgat acagcaaata caaaaagtat
      481 ttattcttgt caacagtttt tgaatttaac aggcgtaaca acaaatccta caattctgaa
      541 aaaagaagga gcgtcaaact tcttctcgca tatgaaagaa atcaaaaaaa taatcggaca
      601 gattcctatc catattcaga caataggaag aacggaagaa gaaatgatag aggatgctcg
      661 agttatcata gaagaactgg gaaaagatac gtttatcaag gtgccggtga atcaagcagg
      721 ccttcaagcg atcaaaaagt tgaaaaaaga aggttatttg attaccggta cagctattta
      781 cacagaatta caagggtatt tagctattaa taatggagca gattatattg caccttatta
      841 taacaggatg caaaatcaag gcattgatgc tatgaaagtg attgattcgt tgcggactga
      901 gatcgaacgt acgcaaagac caacaaaaat attagcagct agtttcaaaa attgtgaaca
      961 agtcactaca gccattcgat ctggagctca tgcgataacg ttaggtaaag agctactaga
     1021 tcaagtatta gagatgccct cgattgataa agcagtgagg ggcttccaag aagattgggt
     1081 gcaaactttc caagcagaaa cgattggtga actaaaaaag gtcgctgatt acttctgaat
     1141 caatttctcc ataaaataaa cgatagcctt ctcgaaaact cgaggaggct atctgacgat
     1201 tcaatattca ttaatttaaa gtttgggtga ctattactaa ctattactta tttctcattt
     1261 aaacgatgta ttccctaacc tctaatacat ccttgtaact ctgaagttac gccagttttg
     1321 aataaatttc ataaaaacaa atgaaaagtg tcgcataaaa atatctttcg tgtttctcta
     1381 gtataacaga ataagaagaa caagtccaga agggatattt ttagtctttt ttaaaataac
     1441 ttttcagtcg agtttgagtt tatgatagtt gtttttgaag cgatacggca agtgaaaaaa
     1501 tagggaagca tgaaagaatc tacttaatgg cgcattgatt catgtgatag aaataaaaaa
     1561 cttttttaaa ttatatcctc atgattgtaa caaatccagt gatttgtttt ggtacaaata
     1621 aaaaaaggcc ccgatgaagt tgtggcaaaa gtggtttgcc tcaaaaataa gaaggaattt
     1681 ccaaaaatca cttctcaaat tttgccacat ccccaattgg gtcaaatttg tttatttgaa
     1741 tatatttttt acataaggat ctttaatagt tacattgtct tttttcatca ctttacggat
     1801 tgttttatcc atgaattccg tatcaagagt ttttgcttcg gtagcaattt tttctagctc
     1861 agatttgtat ttgtctttat tagaaccttt atcctgtttt tttaccattt ttactagata
     1921 atagctttgc tgataagtcg ttggatctgt tacaggaatg atatcagaaa cttccccgtt
     1981 ttttagttta aatgctgctt tttttacttc agtaggaatc tctggattgg ttgaatcaaa
     2041 attcattttt ccatcagttt cctttaatgt tttatttttt ccataagctt gaacaagctt
     2101 ggagaaattt tctccttcat ttgcttcttt ttttgcttta tctgcttctt ctttagtcga
     2161 aaatagaatg atctgtgtac taacttctgg atagaattct ttccaagcag tgtctagatc
     2221 tttatctgtt aattttacat tggctttcaa accgtattgg aaagccagca tctgtttaaa
     2281 gagtttctta tatgtctctt ctgtttggcc aactgctttt aattgttcct tgtagtttgg
     2341 accgagtttt ttgatttgtt cattatattc ttttgttact tcctttgaag aaatctcttt
     2401 tccgtataca tcatcaaatg ctttgaagac aatcattttt tttaatagtg tttgattatt
     2461 tgatttaact tttgggttat cataaaaatc ctgaactgta agtgttccac ctttaaacgt
     2521 tgcaatcgtt tcattggact tgctacaacc tgagaatagt aaaattgcac atgctgaaag
     2581 gcacataatt agtagttgtt ttttcaaaaa atttcccatc ctttccttat taaaaacagt
     2641 ctaacagaag aattagggag acagtctttc attttcgtaa ggttgctgta gatattctta
     2701 gttcgtaaaa atctattctc tctatgatgg agaacattta catagttttc acgagacaag
     2761 aaagaaaagg gttgttaaac ttaatataaa ggagggatga aagatgatca ggattattcg
     2821 gttgattgga tctgttttaa tagtcttagt tggttttgtt ttaggaattc ttgtcaataa
     2881 tgcacttgcg gatatgttta ttggaaatag tgaatggatt ggagcaattg ccggtacggt
     2941 cggacattta gctgtttttt tactagcttt atttcttgct agtaaggtcg aaggaaaaag
     3001 aatagaagat tatggtgttt ctgttcgagg aaaagactgg gggtatttag cgggaggtct
     3061 cgttgttgga attggagtgt ttctgcttat tactagtcca ttatatttga cgggggcgta
     3121 tcggttagat tcaggaaacg caaacattgt gccgctgata acgagtttta ttttatttat
     3181 tgcagtgggg gcatcagaag agcttttatt ccgtggcttt tttcagcatc agatgcttag
     3241 atttggtccg ttaatagcaa tgattggatc tgctgcatta tttgctcttt tgcacggatt
     3301 gaatcctaac atgacatttc tggcagtttt caatatcttt ttagcaggtt gctttttcag
     3361 cgcacttatc tacagtacag gaagtttatt tacggctatt ggtgctcata ttacttggaa
     3421 ttggacacaa ggagctattt tgggtatacc agtcagcgga acgcaagaac aaggtttttt
     3481 ctccactctg atccaatcgc aaaatacaat aattactggg ggaaactttg gggctgaagc
     3541 atctatatca actacattat tcttgttagt cttgattgtt ggtttgttac tctatgcata
     3601 taaaacaaag cggatgaaga aatacactgc tgtttatcaa taaaagatga agaaagcaag
     3661 gctgatatcg gtcttgcttt tttaagtctg tcattgatta aacgaaaaag taaacaaatt
     3721 caagcgaata cacgacatct tttgttagat tttcacaact gactgtcgtg ttctcatcat
     3781 tttcatttta tataattcct ttatcaaata gaaggtaatt atatggagag tgatagaaat
     3841 gaagaaaaca gcgaccgtat tatttgttat tcttgggctg agtataattg cagcaatgat
     3901 tggaatcagt acttctgcaa atgaacgggc aaatgagaat ctttcattta ctgtgaaaac
     3961 tgatcggatt gtttatgaca tgacacaaca agtcattact attccagtca aaccaaacaa
     4021 aagcgtgaat gctagtgatg tacatgctgt tctaacatat ggttgggatg gtaatggaag
     4081 ttcagaaaaa gttattgggg aagtttattt aaaagacgta caatggaccg ctggtattga
     4141 gtatacaata atgatttctg cagaactatc gattgatgag atcaagagta aagataaagt
     4201 tgatttgatt gttttttatg atggacagat gacgatcacg gagaatttga aaccaagcag
     4261 ttggacagtt gttggaccgc caagcagtac ggatagcaca agtagtgaaa gcagtacaga
     4321 aaacacgagc ggtgaaagca gtacagagag tacgagcagt gaaagtagca cagaaaacac
     4381 gagcagcgaa agcagtacgg agagtacgag tagtgaaagt agcacaggaa gcacgagcag
     4441 cgaaagcagt acggagagta cgagtagtga aagtagcaca ggaagcatga gtagtgagag
     4501 tagcacagga agcacgagca gcgaaagcag cacaggaaaa gtaaataatg aacttgattt
     4561 ggtacctatc ataccaacta aggaacaaaa gagaaatgca gggagcaacc taaaaagtgt
     4621 gctaaaacag cctgattttg tttctcgtgg aattgatcat caagaaaaag cgaaagaaac
     4681 agataataga aaaagcgatt taccagaaac tggtagtaga accttgaaca agctaattac
     4741 atggatgggt gtgttactca ttttgattgt aggagcaagc tattttcgtt ctctcttcca
     4801 tcgagtgaaa taaagaataa aagcaacaga tctaaaattg aataaaacga tagatttttg
     4861 agtgaatatt tcattcgaga gtgctgtatt gcctggcgaa gttgtagctt tgccagatct
     4921 atttttgttt actaacatat ttgagaaaca ggaaataaca ggaacacaaa tggaaaataa
     4981 gagcaagaat aattgacaat gcacactgcg catggtagta tctctgaaaa atcagtaacg
     5041 aatctatttg tacgttattc atgtagctgt cggaataagt ctaaataata gataaaaagg
     5101 agtatgtact ttgtttgaag aatttattga tatcaatgaa aggcaagtat atcaattttt
     5161 gaactattgt tatgaaagag acgagaaatt atatgtggtg aaggatatcg ctttagatct
     5221 aaactacacc ctggctaaga tgaattcggt gattcaacaa gcagaatcgt tttgcgaaag
     5281 gtatccagaa tataaattat cttttctttc agaaaacaag atgataaaag tcgagttttc
     5341 ttctcagttt ttactgagta aagtttattc tatactttta gagggaacga ttggttatat
     5401 tttactggat tcactttaca aaggtactta tcaatcctta gaaaatctta gtcaaaaaat
     5461 tatataagtt tgcgtacgat tcaaagaaaa ttaagagaac ttaatactat tttgaaaaac
     5521 tatcatttat cttgcagctt gaaaaaaggt aatccgatag aaggagaaga ataccgtatc
     5581 cgatactttt ttcacttgat gtattggcag tcattcgacg aaaatcattc tgatatatta
     5641 tcaagtataa aaaataaacg tcaactatta gaaaaatttg cgaaacatgc gccatatacg
     5701 cgtagtatag atagaaagaa atggatcagc ctactaagaa tttcgttgca acgaatgaaa
     5761 caaggccact cgattacgta tgtcccagaa gagatgaaca aatttgtgca tccattgata
     5821 acaaaagaag agtttacgca ttacatacta gagccttttt ttgaagcaaa cttctggtcg
     5881 atgaatcaca tcactccaac agagcaagct tacctttatt ttatgtttgg tgtaatgaac
     5941 acctatttgg aagaagattt gttggatact ccagataaag tacaagaaag ttggggctgg
     6001 attgaatcgt ctattgtaga aaattttgaa aaaaacttca agatttgttt tacaacttca
     6061 gaaaaaaatt atctatatgt caatttggca atgatccatt tgtattcaag ggtttttggg
     6121 acaaaaaaga aggtggatgc ttttggaaaa tcagcagaag acagagattt tcagcatata
     6181 tttccagtga tgtatccaat catgcaacag ttttttagtg gggtagctcg cagaattcca
     6241 gagcttaata cttattatga aaagaacaga cggttgattt ttcaatactg tatgttagtc
     6301 agggatattt ttataaaaca cgaacaacct gtcatattct atattcaatc aaagtatggt
     6361 aaaacacagg aattatgggc aaagaaaagg atattatcta tgactgaacg cccaataaaa
     6421 tatagtgcat ccgctgatca gttacctgat attgtcatta gcgattatcc tatcgacaaa
     6481 aaggcatatg atcaaacgaa tacacagata ttttactgga atggacaacc tacaaaaaat
     6541 gattgggcgc gtctgaaagc tgaaatcata aaaatcagga atgagaaaaa tagatccata
     6601 ttggaaaaat tggatttcgt taattaagaa aagcagattg tttatgccaa aattaagaca
     6661 ttgcaaaaag attattttct ttaaaatcga caagatgacc agaaagcaag agttcgttga
     6721 gctcttgctt tcttttagtt ttagaaagga acatcctgat tttatcttcg ctaaatccag
     6781 tcaaaagttt tgcagattgg tcgtagataa tcggtttttt caataaagaa ggggatgtac
     6841 gaatctcaat atatagttca ctcaaactga gttcatctat tctgtgaaca agatttttat
     6901 aactaataga atgagtagag agcatttcgg tcacgccgtt gtttgtcaat tttagtaagt
     6961 ggataaattc atttttggtt agtggttgac gaattaagtt ctgttcgata aacggtatat
     7021 catggacgat aagccaacgt tttgcgcgtc ttgaagacga gcagccagaa cctgtataca
     7081 atttaatcat catacattcc tccaatagct aagtatttat gaaataataa catgaagaaa
     7141 tagtcgaaaa gtgccattta gaggtgtaaa ataagaaaat gttgtcacgt ataatggaac
     7201 tagctagata agaaatacta ttaaatcaag aaaaaagaaa gaaggcacaa gtatgtcaaa
     7261 cacagccgac gcaatagtag tgatcgattt acaaaaaggg gtatgttttg attcttcgcc
     7321 gatacacgaa ttagaaacag tgacagcatt agtgaataaa agaatcaaaa catacgaaac
     7381 gattgggaaa ccagttattt tcgttcaaca cgaagatgct caattagtgc cacaaacaaa
     7441 accatgggag ctattgtcgg aattatctat tcctgagcac agttattttg tgagaaaaac
     7501 ccatgcgaat tcattttata agactaattt gagtgtttta ttaactgaat tggactgtca
     7561 ttcgatcgaa ttatgtgggg cacaagcaga gtattgtata gatacgactg tgaagtttgc
     7621 tcatggatta ggataccagc ttatgatgtg tagaggagca acgacaactt atgataatcc
     7681 ttttatgaaa gcaaaggaaa caatcgcttt ttacgagaaa atttgggata aacgatttct
     7741 gacatttttg gagcaataag ttgtttcttc gtttaaaaaa agcagaatgg atactggttt
     7801 atccattctg ctttattacg taaaatgaga aaataatcct gttctatttt tatgggataa
     7861 accatttatt ttttgtataa aaaatgtttg cgtttacata taattctcct agaaacataa
     7921 aaaggagtga atagcttgag aacaaaacaa gtattaaagg gagcgttggt catcttattt
     7981 gctgtaagta caagcgtccc gcaatggaca gtatatggag agagcatttc ttccgaatcg
     8041 gaatctcggg aggtagaaac cacagaaact actgatgctg gaaatgaaac gaaatcgagt
     8101 acttcacaaa cagaaacaaa tactgaaaca acggttgaga catctgttac tagcacagat
     8161 caagaaacga ccgctaccac agataaccaa caaacagaag aagcaacagc tacaaaaatg
     8221 tcaaacgacg aatcctcttc tgctaaagta agtgacaaag agaatgggac agaaaatgat
     8281 gatatcggta aaggtgaaaa tttcaatggt aaagaatatt tgaattactt cggtaaacag
     8341 atgacagaaa tacttaatgg accaacagaa gacatcaagt caaaattaat agagttatta
     8401 gtcactgagc ttgctgttaa tgattatggt gtagataaag agattatcaa acatctgatt
     8461 gctacttatc tattgtacga tatcgctttt gcaaaaaaca gtgtgttgat gtcgatgctt
     8521 ggaggtacag atgatgggac aacgcctaca gaaaacacag gcttctatcc aaatacaaaa
     8581 caacttcatc aaactgtact aaacaaacaa gatggcaaaa tgatggatgt atatgcatat
     8641 tatgtcgatc aaggttcaga taaaacagtc atgatccatg gcggatttcg agggaattgg
     8701 aataacggga tcgttacaga agaatacaat gatttttata aggccgggta taatttatta
     8761 tttgttgatt ccagagcgac tggtaatagc ggaggcgatt atgtgaccta tggacaatat
     8821 gagtcagatg acgtccttta ctggataaat caagaagttc gagagcggcc atctcaaaag
     8881 attttacttt atggtggttc gatgggagca gctacgatga tgtctgtatt agcgaaagat
     8941 attcctgtca atgtcaaagg aattattgaa aattgcggat ttgcatcaat tgatgaacaa
     9001 ctacgtttta cgtacagcca gacagtagcc cccgcactac cggatgccat aaaaaatcag
     9061 ttagacatca ttggggatca agagcatgaa gatttattta tgggcctttt gaaacaatac
     9121 tattttgatc aggagatgca tttggataca aaagctgctc tacctacgat tggaatgtca
     9181 gattcattgc ctaaattgat tatccatgga acagcagatg atgtagtacc tgtgtctaac
     9241 gcgcaaaaat tatatgagtt atcaggaggg tataaagatc ttttattagt agaaggagca
     9301 gggcatggaa aggcacagga agttgaccat gctgcctaca cgaaacatgt aacggacttt
     9361 ttgaaagtag tgttccatga tcagataaac gtaaagtatg tggatgaaaa caataaaagt
     9421 ctactcaaag accaggacga aatccagctt tacggagctt atggagaaaa ttatatgaca
     9481 gagcaaaaga cattcgaagg atacgaatta gcaaatgttg aaggaccgac tgaagggatt
     9541 tttaatgaga cgataccaac tattattttc tattacaaaa aaatcccagt agctccacca
     9601 aaaaagcaag atccgacaga gaatgcagac aataagggaa agaatgaacc tcgagaggat
     9661 caatcaagtg atgatacgca accgattcag atgacagtga aagtacaaaa aaagacagat
     9721 gcaaaaaaaa gaatgttgcc gaaaactgga gaaaagaaac attcgcttct catttattca
     9781 ggtggatttt tatctgttag cacgattatc acatggattt ggcgaagaaa gagagggtaa
     9841 atgaatgaaa tggttcaagc gaatagtgat tgcagtacca gttatcatcg tagttatttt
     9901 agtcactgta tttttgatta atcaaatcac accaaagccg attagcttgc ttgttagaaa
     9961 acaatttgac acaagtgaaa aagaacaagt atatgcccga ccagatgatt tccagcaaaa
    10021 aatcgaacaa atcgatataa aaaaagaaat atcctatcct tcaaagtaca aaaataataa
    10081 tatggatatc tacacaccga aagtggaaaa gaaaaaatta ccgattcttt tctggatgca
    10141 tggaggcgca tatgtaggag gggataaaaa tgattgtcgt gattatttgg aatatctatg
    10201 ttcagacacg cagcaaatca tcgtaaatat agattatgaa cgatcaccgg aagcaaaaca
    10261 tcctacacca gttatccaat tgaacgaagc cattcaagca gctaaaaaag agataaaaga
    10321 tcaagcagat tggtcgaata tttcgattgg tggaaattcg gcaggtgcac aaattagtgg
    10381 agaatatttg ttagcacttc aaaatgaaga aattaaaaaa gctgatcatc ttgatccgac
    10441 tttggagaac aagcagatta cgaagtttat ttctttgtct ggtctgttgg atccttctgc
    10501 acttactcaa gtaagtgata aaatctctag ctttctttat gaaaaatgtg gatgggctta
    10561 ctttgataat aaggactttg aacaatcaga gaaggtcaaa agtttagcct tggtcagaca
    10621 tgcggatcgt tggacgcaaa acacattctt aacggatgga aatacaaata cgtttacgaa
    10681 acaaatggaa gaagtaactt ctgtatttga gaaagcgggg gtgaaagtca caaaagtaga
    10741 ttatgcggag aaaaatgctg ttttgaacca tgaatatcag tttgatttca gcaataaaca
    10801 agcgcaagaa acatatcaaa agttagtaat gtttttcaag gagtaaagtc ttatgatgca
    10861 aaagaggttg taatctgtca cttagctcca agtcacaagg agcaatttca ataaacaagc
    10921 ttttcatggt ttatgaatat tgtaacttgt gactgaggag ttagagatgg caaggggcac
    10981 cttttattcg aaatttggga atatcacacg attattgtca cgatctcttt tacgtaaatt
    11041 ttataagtca gatttgttgt tttgatcgtt taaaaaaagc aacaaatccg aagcctgcgg
    11101 aggcaagaag ggacaaaaag ccgagtggta agcaaaagaa tgctggttcc actaatattc
    11161 cgttgttatt gatataaggc tgggaacaaa gatgaatagc aaataaaatc aatgcactag
    11221 cgaaaaaaag caaagaaata tggatagctt tcataagcag cacctccttt tttataattg
    11281 tatgataaat agattaagaa tctataaatg tgacaagttt gttaggatgt gaataaaatg
    11341 atcatctagc gaacttgaaa caaagatggc taatgataag caattaatga ttcagcaatc
    11401 agataggtac aaagtttacc atcatacgtc tagaccaata atagaaaata tgggaatata
    11461 atagaaaaga tttaggatac ccccaaaaga atttccccaa aaattcgatg tatcctaaac
    11521 ttttttattt tacataacaa tcatatcaac tgtgaaataa aattacaaat gataacctaa
    11581 aatgaggcca aaagccagtg ttatcaagga aatacttaat tcaccaaaat tttttttaat
    11641 tttttagaaa ataagaaaca aaaataataa aaaaaagaaa agataaattt tttactactg
    11701 tatactaact ttgttatcgc atctaacaag taactcgaat aataccaata caaccttctc
    11761 caaagatgcg atgacatacg ttctaaccca ccgactattg atgttctgta ccacccttgc
    11821 agaaccaaaa aagccactac caaatatttg gtagtggctt tttttgtttt atggattttt
    11881 cgctttttct gttatggtgc tattctttga tttcagaaat agtatgtcga actttagcga
    11941 tagaacgacg tgattctttt tcgttgtaaa acatcaaaat cacatataga gagtccaaaa
    12001 tgcttagttg agaaatacgg gaagctaaag cttcagatcg gaattctgtt tcttcagaaa
    12061 tagaaataaa aacgacatcg ccaagtttag caagggaaga attagcttgg ctagtaataa
    12121 cgattgtttt tgctccagtt tttcttacgg tttcagcaat atggattgtt tcttttgatt
    12181 gccctgtgtg agaaatcaaa acagcacagt ctttttccgt caataaagaa gcttccatca
    12241 attgaatatg gtaatccgtg ctgtgagaag ttgcgatagg ggaacgcaaa aatttatgat
    12301 aagcgtcagt tgctacaatc tctgaaccgc caacaccgaa aaaatagaca cgtttagatt
    12361 cattgataat agtagccgct ttttttagat ccttttgttg taacaacttt tttgtgtcat
    12421 ttaaagttga aatactagac tcgaacacct tttgcgccat agtgagctca gtatctgttt
    12481 tctgaatatt ttcgtggata gaaatagcag atagatcatt ttcttggatc aacatggcca
    12541 ttttaaaatc tttaaatcca ttataaccaa gtttttttgt aaattgaaaa aaagtagagt
    12601 cagcaatgcc cagttcactt gctaaattgc taataggact atgacttact ttgcttggat
    12661 tttctaaaat ataatcggcg atagcctgtt cttttgggct gaagtcgttg tacattgttt
    12721 tgatttgtag tcttatggag acgctcatga gaattcctca ttttcataat aagattatca
    12781 ttttttccgt tctcattaat gttaaagata caaggagagt aggaaaaaat caaacaaaaa
    12841 atatttttgt aaaatctatt tacaaaaaaa tttttttgta taatgagggt ataagaaatg
    12901 gaggcgctat catggaaatt ggtgtaattg gtttgggaaa aatgggattg aatttagctt
    12961 taaacttaaa agagcaccat cacaaagtac aaggactcga catttcaagt acagctgtta
    13021 gtcaggcaag agaaaatgac attcctgctt atcaagagat ctctgaattt ctagctactt
    13081 ttgagcagaa aaaaatcatc tggttaatgc ttcctgctgg agagataacc gaaaacatgt
    13141 taagaaaact ttttccaaaa ctcggaccag gagacattat tattgaaggc ggaaactctt
    13201 attataaaga ttcaatccgt cgagcagaag agtttcagaa aaatgaaatc ggttacttgg
    13261 attgtgggac ttctggagga atcgaaggag cacgacatca agcctgctta atgattggag
    13321 gagataaaga aacttttcta tccgtggaac aattattcaa agatgtagca attgaaagag
    13381 gatatctgta tgctggtgca tccggaagcg gacacttctt gaaaatgatc cataatggaa
    13441 tcgaatatgg aatgatgcaa gcaatcggtg aaggattcca acttgtacaa aaaagtgagt
    13501 atgcttttga cttggaacaa gtcgcacgtg tttggaatca tggttcggtg attcgcggct
    13561 ggctgatgga aatcatggaa gatcagttaa acgaacatcc caatttaagt aattatcggg
    13621 gaatcgtttc tgcatcaggt gaagcaaaat ggacggttga aacagcgcta gaaatggctg
    13681 ttccagttcc agtaattgca actagtttgt tcatgaggaa tctttcacag gaagaagata
    13741 gtttttcagc aaaagtagtt tcagcactaa gaaatgggtt tggcggacat gaaatagttg
    13801 aaaagggtga gtaaaatgcc agattatcat atagcaatcg ttaattccag cagtttcgga
    13861 agagtctttc cacaccactt ggaaagatta aagtcagttg gagacgttca tttctttact
    13921 gttgatcaag agattccagg aaaagaacta gcggagttac ttaaaggatt caatatcatt
    13981 attgcaagtg ttacgccatt ttttcgacga gatttttttg aaaacaaaga tgaactgcta
    14041 ttgatttccc gacatggtat tggttacaac aatattgatt taaaagcagc aaaagaacac
    14101 cagacaatcg tatctatcat acctgcttta gttgaacgaa atgctgtagc agaaaataat
    14161 ataactaatt tgttgtccat gcttcgacgc acgacacaag cacaagcaag agtcaaggac
    14221 gatcgatggg aagatcgggc ggagttcgtc ggtaggacgc tgtttaacaa aacagttggt
    14281 gtgattggtg caggaaatac cggaagcgga gtaatcgaaa ttttgcgtaa cggttttcgc
    14341 tgtgatgttc tagcttatga tccttacaaa tcagatttat acatcgaaag ctttggtgca
    14401 aaaaaagtag aacttcaaga attactggaa caatcagata tcatttgttt atgtgcgaat
    14461 ttgacagaag agaactatca catgatttct gataaagaag tcgatcagat gaaagaaaat
    14521 gtttatctat ctaatagtgc aagaggcgct ctagttgatg aagaagcgat gattaatggt
    14581 ctgaaaagcg gaaagatcgc aggatatgcc acagatgttt tagaagaaga accgggacgt
    14641 caagatcatc cgtatttagc gtttgaacaa gtagtgatta cgccacatat atcggcctac
    14701 acaagggaat gtttagaagc aatgggtgaa aaatgtgtca gagatgtcga acagatcagt
    14761 cagcaccttc ttcctgaacg ttctgtccag acaaagagca actatataaa aggatgatga
    14821 agaaaatggt gaacggttta aaagtgaaaa caggccctca attttattta tatgaagaag
    14881 gtggtatttc aaaagtttct gatctcttga aatcatacgg cgcgaaaaga gtactggtca
    14941 cccacggaac ggtatcatgg gaaaaggcgc tacctaaatt agtatttttg aatgacgaaa
    15001 cgattcaatt tttttatcat cgttattctg gagaatgtag ttatgctgaa gccagacgaa
    15061 tagctacaat catcaaaaaa atgaaatcga tttcgtagtt ggcgttggcg gaggaaaact
    15121 gaccgatcta gtgggttata gtgccaatct tgcaagaatc gatttcggag tcatccctac
    15181 tttagctagt aattgtgctc catggacacc tcttgctgtc atgtataagg agaatggaca
    15241 agcagaaggg aaaacagaac acttttacag acaagctgct ttttttataa cagatcccca
    15301 attagtgatt gattcccctg ttccatattt cattgccggg ttagcagata cactagcaaa
    15361 atggtatgaa tctgagctca tcttagaaca agattttttg caagatgaat catttttgaa
    15421 gctagcacaa gatactgcga agatctgcaa agaagagatt ttgaatcatt ctgctaaagc
    15481 aatccaagat atggcacaaa gaaaactgac atcggagttc aaacagcttt cagagattat
    15541 ctttgctgtt gctggtttag ttggaggatt aggagataaa tacgcaagaa atgcggcagc
    15601 acatgctatg catgacgcta tcagtaaata tattccggaa agccatcgtt ttctacatgg
    15661 agaaaaagta gcgtatggga ttttctatca actggcacta gaaggtcgct gggaaaaaat
    15721 agacgagtta tatcctttgt atcgggaatt agaactgccg gtttctctag aacaaatggg
    15781 attatttccg aaagataaac agataataga taaaatggct gaatttattg attcgaaaga
    15841 gaaagtgcat ttgattccta tagaggtaac acagaaatca ctgatacagt caatgatgga
    15901 actggaaggt tatatcagaa agatctgaag gaggaggaca catggaaaca ttaagtgtag
    15961 tacaaagttt gttgattgct ttatgggtag ccgcggttat gtcccgctgg ttaggtggag
    16021 gagccacgtt gaccttacgt ttttctcctt tgatgactgg attagtcgtc gggttgatca
    16081 tgggggaagt tgcacaagcg atgattgtta cagccgcttt gcaaatgatt tatatggggg
    16141 ttttttctcc aggaggatca atgccagctg aaccatctat tgcagcagct atcgcagtac
    16201 cagtcgcatt attaggggat ctgtcgccag aagcagcgat tgccgttgcg gtgccagtcg
    16261 gattgctcgg aagttacttg tatcagtttc gttttttcat caatactttt ttaggtaaat
    16321 atacagacaa agctgtagaa gatttgaata caaaagctat ggcccgatca attattcttt
    16381 atccaacggt tgcctcattt ttattattcg ttccgcttgt tttcattgct ttatatttag
    16441 gggcgccatt gatcgctgat gtaatcaaag ctttagaggg aacagtcgtt atccacattc
    16501 ttgaagtagt aggtggaggg ttagcggcaa tcggtatcgc gacaactgta tacgttatcg
    16561 gtcgaaaaga ttatctggtc tttttcttcc ttgcttattt tatgagtgtt gttttgaaat
    16621 ctttagatat tacgatggtt acttatgcca tttttgggat tattatcgct ttgatctttg
    16681 tccagtcgca aaaagggaaa caagtacagc ctgccacaag caataacaat tcagcatctt
    16741 ttgatgacga agatgactat gatgacggat tttaatttag gaggaatggg aaatggctga
    16801 aataatggat aatcaaacag gtgctcctga agaaatcacg aaaaaagatg taacaaaagc
    16861 ctatctgaga tggcattttg caaacgaaat tcctcactct tttgaacgtt acttggcgcc
    16921 atcactacta tacggaatga tgccaatctt gaaaaaactt tataaagatg aagactcttt
    16981 aaaagcagca tataaacggc agttactgtt cttcaacact caattaagct ggggtggcgg
    17041 tgtgattact ggcctaatgt cttctatgga acagcaaaga gcagaagaag agtatgaaga
    17101 aaaagagatc ttgatgcagg atgacttgat gtataacacg aaagcgggat tgatgggggc
    17161 actagcagga atcggagatg caatcgattc aggaaccgtc caatatattt ttatcgcaat
    17221 cgcggtacct tgggcacaac agggaagtcc tttaggcgca ctttttcctt ttatctgctt
    17281 tgggttgtat caggttttac taggggtatt tttcgcaaga caagctttca ctatgggccg
    17341 taatgctaca ggcctaatgc aaaacactgg tgttcagaca gcgattgaaa tgctatcagt
    17401 tttagggttg tttatgatgg gggtgcttgc gggaaactat gtaaaagtag aatcttcatt
    17461 gaaatttgcg atatccggac gtgagtttgt tatccaggaa attcttgatc aaatcgtgcc
    17521 agggatatta cctttagctg tcgtaatggg tgtgtacttg ttctatacga aaaaaggatt
    17581 gaaagtcaca caagcattat tatggctgac tggaatatta attgtgctag caggaatcgg
    17641 tattttataa aaagaaggga acgtgaataa gatgggtgta gtcaatttag cgcgtgtgga
    17701 tgagcgtttg atccatgggc aagtaatggt aacgttatct caaaaaagtg gagtgaattc
    17761 catttttgtt gtagacgaag ttgtagcaaa agataaattt atgagagatc tttacaaaaa
    17821 tgcaggaagc cgtacaggac aaaaaacaat tgtcattaca ccagagaaag ctaaattcta
    17881 ttgggatgaa tatcaattta aagaatacaa ttgtattttg atcgcaaaaa cagtccaaac
    17941 gatttacgac ttagtaaaac acggaatccc catggaagaa ttgaatattg gagggattgc
    18001 tcaaaaaaat cctgatacag atcttttagt gacgaaatct gtttatttaa ataaatcaga
    18061 tgctgaaaaa ttgaaagaaa tgaatgaaca atatggcgta aagaatattt attttcaagc
    18121 cactccatct gcacctaaaa caggattaaa agatgtattg aacaagtttg atttgtcata
    18181 aacaaatgct tagaaaaaag ataaagaggg cgaaaaaatg aagaagaacg agctgtttcg
    18241 tgattgggaa tttcgttatc gctatattta ccgtaagcgc cgtacaaaaa agagtaaaca
    18301 gcgttttctt tcagcattag tatcagatat ttacagtatg agaacagatg tgacagtcat
    18361 tgcttacgat acgctagcct accgatcaaa aaatatttat gttggagata tcgaaaaagc
    18421 agagaaagtt atctgtactt attacgatac acccgttcat gcattaggaa gttatttcat
    18481 gtttgattgg aaagaccaaa ggaaaaaaac aatctactct atattattgt ccttcatttt
    18541 gttgttcagt ttaggttggt ggggaatgat gatatataac aaaaatcctc atcacgtatt
    18601 cgatctgcta tccgtataaa caggtatcac tgtactagca tttgggagct actttttctt
    18661 attgggaaaa gcagctcgcg gatggcctag cagacaaact tttattcgaa atacttcatc
    18721 catattaacg atgctagaaa tgatccgtac gattgatgat ccgagtgtag cgtatgcgtt
    18781 tgttgatgaa ggctgttatg gagaaaaggg cttagacagc gtgagatcgg gtatgaaaaa
    18841 agaggctatt cttttttatc tagactctgt tggggcagat acaccgctac agttttcggg
    18901 aaattatttt tcaaataaag aacagtggct gaaacaagtt gataagttga aagaaaaaaa
    18961 cgtcaattat atttttagtg caagaaaaaa gcaagcgcag ttcttctatt tgaccaaaac
    19021 agatttacga gggaaaacat ttaattggca aaatgccaat cagattattg ctctttttcg
    19081 ataagtaaaa agtgcaaaac aaggagtgag aagactaatg ttggaaatca tgatcgttac
    19141 acatggtaag ttgagcgaag gactgaaaga tgcggcggaa gtaattgtcg ggacatcgag
    19201 ccatattgaa acaatgtgct tagagtctgg ggaggacatc caaacattcg gagagaaggt
    19261 caaagaaaaa ttaactatga tcaacacagc agaacccatg ctagtatttg ttgatctaat
    19321 tagcgcaagt ccgtacaatc aagcgctctt ggcagtcaat gaactgactg aagaaaagaa
    19381 agcagccact tatgtcatag ggggcgtgaa tctgccaatg ttgttagaag caatcaatca
    19441 tcagatgctt cacacaccga tagaagaagc ggtggaacaa attgtcaaac aaggaaaaga
    19501 taatttaact gtttggcatg cttcagcgga agaaaaaaaa ttagatgagg acgattttta
    19561 gaaggaaggc tgaaaagatg aagtggggat ttagatggta tggtgaaaaa ggggattcga
    19621 tcccattaaa atatgttcgc caaataccgg gaataaatgg gataattgga actttgctga
    19681 ctaaaatgcc tggagatgtt tgggagattt cagaaattga ggagttgaaa gcatctgttg
    19741 agagccaagg actggaactg cttggaattg aaagtgtagc gatccacgat gcaatcaagg
    19801 cagggacaga tgaacgagat tactatattg ataactatat acgaacaatc aaaaacttgt
    19861 ctcgatgtgg ggttcgattg atttgttata gcttcaaacc aatttttgga tgggcgaaaa
    19921 ctgatttgtt taatgaaaac aacgatggaa gctattctct tttatacgat cagaaaatcg
    19981 tcgatcagat ggagccagga gaaatgtatc aattgataca cagccagtca aagggattca
    20041 aattgccggg ttgggaagaa gaacggttga aaaaattcgc tcagctggaa aaactgtatg
    20101 aaggaatgac cgaagaagaa ttatttgaaa atctgactta ttttttagaa aaagtgattc
    20161 cagtgtgcga aaaagcagat gtaaaaatgg ctatccatcc agatgatccg ccatgggaac
    20221 tttttggttt tcctagagtg acgaaaaatc ttggcgactt gaagaaaatt ctaaatgcag
    20281 tagattctcc atataatgga ctaacgctgt gcacaggatc tttaggggca aatccggaaa
    20341 acgatttagt tgaaatcatc catgaggtag gttcgcgcat ccattttgtc cacttcagaa
    20401 acgtggagtt tttaggagaa agaaagttca aagaaacggc acatccctct acagaaggct
    20461 cccttgatat gtatcatatt atgaaagcgt tggtgcaaga agggttcgac ggtcctatac
    20521 gccctgatca tggtagaacc gtgtggggtg aagtggctat gcctggatat ggcctgtatg
    20581 atcgtgcaat gggactcact tacatgcaag gtctatatga ggcgataagt aaggaaaaac
    20641 cactgggaga gcattatgaa taaaatcaag ctcttcatct ttgatatgga tggcctttta
    20701 ttagaaactg gacgtttagc ttatcgtgct tatgtaaaat cagcacaaaa gtatgattat
    20761 gaaatgcgta aggaagtcta ttatttacta actggccaaa cagaaatggc gataagagaa
    20821 caaatgggca ttttgtacgg agaagatgtt ccatatatca aatggcgaga agcaatcaat
    20881 caatataaag aaaaaatcgt gaaagaagat aagagagtat atacgaaaaa aggagcagaa
    20941 gaaattttat cttttgcaaa agaaagagga atccatacaa tcgtggcttc gtctaataca
    21001 cgggtaaaag tagaaatgta tttaaaaatg gaaaatctat atgccttgtt tgatcaaatc
    21061 atttcagggg atgatgtaaa aaaaggaaag ccggaaccag agatcttttt gaaagcttgt
    21121 tcaaaaatga atattcctcc aagtgaagca cttgtatttg aagactcgat tgcagggatc
    21181 gaagcagcaa ggcgagcggg cattttgtct tttctcatca aagatcattt gatagggttg
    21241 cccgatcata atgggaagca taagttgaaa gtagatgtaa gtttatatga atccaataaa
    21301 gcagactatg aattttatga cctgcatcaa gcaaaacgat ttttagaaag taaagggttg
    21361 tatctctaat aaagaggact attttctagt cctctttatt tattgtcctg cacgactgag
    21421 ggaacagatg aaaaagaagt aattttttat tttgaagtat ctaccttatt tgtagtgaac
    21481 aatttagaac aaacacaaaa cgcatctact gttatctacc agtagatgcg tttaaagaga
    21541 agaacgagaa tcgtccatat gagggtttcc actccttatg cagatttttt taattcttgc
    21601 actgcttgtt cgatcgtaac acctgtcgct acatgattgg tattttcttt gtcaaaaacg
    21661 acaaatagat tcaaatctgt atccaaggtt actcgatatt gtatatcttt gttatagaat
    21721 gtcatagcca ttctcctttc tttaaatact tgctgaaagg caacgaacgc gttgataacg
    21781 aaattccatt tataagtata ccaccaattg aaaggttttc atagttaaga aattttaaag
    21841 tcaaaagttg cagataaaag caaataaaca agaaaacaaa aagtgaatca atcgcggtta
    21901 ttcaactttt tcttcgattc gaagacaata gaagacaatg aattttatat ttcattgcat
    21961 tatccttgtg ttattagaaa aagcatgata tattaaatga gtaatctatt ttgaaacgta
    22021 atttgagcga tatatctaca tagataaaac tccttttgcc tatcaaatat ttattgcaac
    22081 gaaaaaacgt acattgatac gtatcaggag gaatttattt atgaataacg gtacagtaaa
    22141 atggttcaac gcagacaaag gttttggctt tatcactggt gaagatggaa atgatgtatt
    22201 tgcacatttt tcagctatcc aaggtgacgg cttcaaaact ttagaagaag gccaagcagt
    22261 gtcttacgat gttgaagatg gtcaacgtgg ccctcaagca acaaacattg ttaaagctta
    22321 ataaaaattg acttttaacc gtcttttcga aagaaaa
//
LOCUS       DAIGWC010000046        21822 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.047, whole genome shotgun sequence.
ACCESSION   DAIGWC010000046 DAIGWC010000000
VERSION     DAIGWC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.047"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(109..555)
                     /locus_tag="NOB74_001785"
     CDS             complement(109..555)
                     /locus_tag="NOB74_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HCI1220973.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(582..758)
                     /locus_tag="NOB74_001786"
     CDS             complement(582..758)
                     /locus_tag="NOB74_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HCI1220974.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(920..1348)
                     /locus_tag="NOB74_001787"
     CDS             complement(920..1348)
                     /locus_tag="NOB74_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI1220975.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            1440..2300
                     /locus_tag="NOB74_001788"
     CDS             1440..2300
                     /locus_tag="NOB74_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HCI1220976.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLKQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            complement(2392..2742)
                     /locus_tag="NOB74_001789"
     CDS             complement(2392..2742)
                     /locus_tag="NOB74_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCI1220977.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(2757..4484)
                     /locus_tag="NOB74_001790"
     CDS             complement(2757..4484)
                     /locus_tag="NOB74_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCI1220978.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEEAKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            complement(4698..5624)
                     /gene="trxB"
                     /locus_tag="NOB74_001791"
     CDS             complement(4698..5624)
                     /gene="trxB"
                     /locus_tag="NOB74_001791"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HCI1220979.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(5769..7202)
                     /locus_tag="NOB74_001792"
     CDS             complement(5769..7202)
                     /locus_tag="NOB74_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI1220980.1"
                     /translation="MGFRKDFLWGGATAANQCEGAYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQVKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(7202..8605)
                     /locus_tag="NOB74_001793"
     CDS             complement(7202..8605)
                     /locus_tag="NOB74_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI1220981.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLSADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            8836..9738
                     /locus_tag="NOB74_001794"
     CDS             8836..9738
                     /locus_tag="NOB74_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI1220982.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            complement(9778..11658)
                     /locus_tag="NOB74_001795"
     CDS             complement(9778..11658)
                     /locus_tag="NOB74_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1220983.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEAEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVSFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAVSGIYLMASGTISYIMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(11754..12605)
                     /locus_tag="NOB74_001796"
     CDS             complement(11754..12605)
                     /locus_tag="NOB74_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1220984.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVIQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            complement(12931..14715)
                     /locus_tag="NOB74_001797"
     CDS             complement(12931..14715)
                     /locus_tag="NOB74_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1220985.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRTTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVLVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            complement(14715..16466)
                     /locus_tag="NOB74_001798"
     CDS             complement(14715..16466)
                     /locus_tag="NOB74_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1220986.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTK
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            complement(16607..16831)
                     /locus_tag="NOB74_001799"
     CDS             complement(16607..16831)
                     /locus_tag="NOB74_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HCI1220987.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            17082..18668
                     /locus_tag="NOB74_001800"
     CDS             17082..18668
                     /locus_tag="NOB74_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HCI1220988.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETVEEIE"
     gene            complement(18734..20509)
                     /locus_tag="NOB74_001801"
     CDS             complement(18734..20509)
                     /locus_tag="NOB74_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HCI1220989.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVEKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGCLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(20722..21624)
                     /locus_tag="NOB74_001802"
     CDS             complement(20722..21624)
                     /locus_tag="NOB74_001802"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HCI1220990.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
BASE COUNT         6238 a         4712 c         3800 g         7072 t
ORIGIN      
        1 aacagctaga agaaagaata agattctttc ttctagctgt tttttagttc tttttttacg
       61 aacacaaaaa actgcggaca atcactgtcc gcagtttaaa tgataaaatt aagattgtaa
      121 tagttctttc acaatcgcat tcacttggtt tccatctgct tttcctttga ctttaggcat
      181 aattgcaccc ataactttgc caaattcttt cattgatgaa gcaccagttt gagtgattgc
      241 ttcttgaaca agttgtcgaa tttcttcatc ggaaagttgt tccggcatat atttttcgac
      301 tattacaatt tcacttttta ctttttcagc taaatcgtca cgtcctgctt cttcaaactc
      361 atgcaaagaa tcacgtcgct gtttcatttc gcgagacaac accgttagtt cttcttcttc
      421 tgtcaagtcg tgaccttctt taatctgctc gttttgtata gatgacttga tcattcggat
      481 gacttgtaaa gattccttat ctttcgcttt catcgctgct ttcatgtcat cgtttaatct
      541 acttagtagt gacacactac caactccaat tcatcacaga actagaattt tttgcgtttt
      601 ctagctgctt cagatttttt cttgcgtctt acacttggtt tttcgtagaa ttcacgttta
      661 cgagattctt gtaaagtacc cgcttttgac acggaacgtt tgaagcgacg aagagcatcg
      721 tcaagtgatt cgtttttgcg aacgactgtt tttgacatgt taattccctc cctccgagct
      781 taaaaagtaa ccgtaattgt tattgaaata tatctcaaaa aacaagactg tcctgtaaat
      841 attatatcta atgctgtttt gaccgtcaag gaaatcttgc ttttttttaa aattatcaaa
      901 tgttatttta tttaaaccct tattgacaat tttcacatct tccgaaaatc tcgaatctat
      961 gcccttcgat cgtgcatcca cctagctgtt cttcgaaata attcatcgga cacatatgga
     1021 tttctttcgt tgttccgcac actgtacaga taaaatgatg gtgatggccg atttccccct
     1081 gacagcaatg aaaacgaaac ttcatttctc catttaaatc ggtttcttcc agtaaatcga
     1141 tctctgcaaa atcatggaga ttccgataaa tcgtatcata acttacccct ttgaattcct
     1201 gattcatata gtcaaaaact tctttagcag atacgtagcg gttacgcttc actaaataag
     1261 ttaacaatgc ttctcttttt ttagtatatt taaaaccgtt atttttcaat gtttctaatg
     1321 attgttcgat caatgtctgt tttttcatga cttattcctc caaatcaaaa tgattacgaa
     1381 gtacgcattc tagagtatgg tataataaac ataaaaaaaa tgcaagtgag gttttatcca
     1441 tgtcttccga ttctacagaa atcgttactt tttttgtcat ctccgactct gctggagaaa
     1501 ctgcgacaaa actagcgcaa gctactatgg ctcagtatcc taccgttgag ttcaacctat
     1561 tccgcagaac gttcgtgaca gatgaaaaaa cattaaagca ggcattgcaa gatgcattag
     1621 aagaaaaagc acttgtcctg catacattaa tcaatcaaga actgatcgag ataacacgtt
     1681 ctttttgtga agaacatcaa ttatttagtt ttgatgtgat gacgccaccg atatcagaaa
     1741 ttgaacgttt aaccggtatc aagccaattc ggcaacctgg tgccctccat ttattgaatg
     1801 agaactattt caaacggatc aaagcaatgg aatttgctgt aaaatacgat gatgggaaag
     1861 atcctcgtgg ttttttagaa gcagatgtcg ttttgctagg cgtatcccga acttccaaaa
     1921 cgcctttgag cttgttttta gctaacaaaa atttaaaagt tgccaattta cctttgatcc
     1981 cacaagcaca tattcccaaa cagctttggg agatcgatcc taaaaaaatc gtgggactaa
     2041 cgaataaccc agatatttta aataatatcc gtaaagaacg gatgcgctct tacggattaa
     2101 accctgatac tgcttattcc gatatcgaaa aaattagagc tgaactcgat tttgcgaatg
     2161 atctttatga aaaactagga tgtgtagtga tcaatgtggc atctttatct attgaagaaa
     2221 cggcttcgct tattttgaat gctttagacc tagaagatca tagttattat ggaactgaaa
     2281 caacagaaaa aagcgattaa tcatttttgt ctttttctta aaaaacactg gagtgtgaca
     2341 acgaagaaat ttcgttgtca cactccagtg tttatctatt tgcacctatc gttattgatg
     2401 ttccacatgt ttgagtgtct ggttcaaaat atccagtaca tgagaatcat caagactata
     2461 caaaatcgct tttccctcgc gatgagactt gacgacatga ttttctctta ataaacgtag
     2521 ttgatgcgat acagcagact gctccatttc cactgcttgg gtgattgctg tcacattttg
     2581 ttccccgtct ttcagatata gcagaatttt aagacgagtg ggatcactca acattttgaa
     2641 taattgactg actttctcta cttttgattt ttgcgtgtct ggcaatccat tcacctccaa
     2701 cttgaaaaaa gactgacttc taaagtttac cactttttcc atcagtctca agttttttat
     2761 tcttctgtca tctttttgat aatcgcttca taagaggcta ctttttcggc tgcgtcttct
     2821 gtagagcttc cttttacacc aatataaaac ttgattttcg gctcagttcc tgaagggcgg
     2881 atagcaatcc agccattttc ttccaatgta tatttcaata cgtcggatgg cggtgttgtt
     2941 agtttttcta cgtttccttc acggtctgtt ctcgtcaatt ctttaaagtc ttctgtttga
     3001 ataacttttg ctccggcaaa ttctgtcggt gcttctttac ggaatttttc catcaaagca
     3061 gagattttcg cagaaccttc ttgtccgctc attgtcacag aaatcgtttt ttctgcaaaa
     3121 tagccatagg tttcaaaaat cgtttgcaag ccgtcataca acgttttgcc ttgtttttta
     3181 tagtaagctg ctacttctgc taataaaagc aatgcttgga tcgcgtcttt atcgcgaaca
     3241 aaaggtttaa ctaaataacc ataactttct tcgaatccaa acataaaagt atgtgaatgg
     3301 tcttcttcga attgttggat tttttcagca atgaatttaa accctgtcaa cacattgaac
     3361 atggtagcac cgtagtgttc cgcaattgct gtaggcaatt cgctggaaac gattgatttc
     3421 aataccgctg cgttttctgg taaagtgcct cttgattgat gtgcttccaa aatatattga
     3481 gcaaacaatg ccccgatttg gttcccagtc aatacttcat aagaaccatc tggcaaacga
     3541 accgctgcgc ctaaacggtc tgcatcagga tctgttgcaa tcagcaagtc agctccttct
     3601 ttttctccaa gtcgtatagc atattcaaaa gctgaatgtt cttctggatt tggcgatttg
     3661 accgtagtga aatctggatc tgccacagct tgttcgggaa ctagtacgaa ttgttcgaat
     3721 ccagcttgtt tcaacgcacg ttcgcccaac attttccctg ttccatgaag tggcgtgtac
     3781 acaagtttca aatctttccc cattgtttct accaattcac gatcaatcgt cactgctttg
     3841 atttcttcta gataagcagc gtccacttct tctccgatga tcgtgatcaa cccgctatgt
     3901 ttagcttctt cgtcagataa tacttcgact tttagcggat tgctgacttc acggacatat
     3961 ttcgtcaatg catctgcgtc tgcaggaggc atttgtccgc catcttctcc gtagacttta
     4021 tatccattgt aagccgctgg gttgtgagat gcagttacca tgattcccgc aaacgtcttc
     4081 aaatgacgaa ctgcaaaaga aagctctggt gttggacgca gactttcgaa tacataagac
     4141 gggatattgt gatgtgccag tgttttggct gcttccattg caaattctgg tgactgatgg
     4201 cgtgagtcat aagcaatagc gacacctcgg cgttttgctt cttcaccttg tgtatccatg
     4261 aaacgtgcta gtccttctgt tgcttgtctt accgtataga tgttcattcg attgatccca
     4321 ggtcctaaga ttccccgcat gcctgcagta ccgaattcca acggtgcata aaaagcatct
     4381 tcaagttttt caggatcttc acccagatca tttaattgtt tttttaagtt ttcttctaaa
     4441 ttttcttcat gtacccattg ttcatacact tgttcccaag acatgaaaat aacacctctt
     4501 tctgaaatat ggttcttaat aagtatagca ttcacttatt agatatgaaa gtatgaggac
     4561 caaaaaacgc ttaaatcaag aaaggattct tttatcaaaa ggtgttggac gtgttcgcat
     4621 aaatcagatt cagtaaattt cacgcgaaaa aaaagagtaa aagaacaatt gaacccgttc
     4681 ttctactctt tttaaactta tgcagttgtt tcttctaaag attccaagta tttatacact
     4741 tgttgtccag caataccgcc gtcaccaaca gctgtagtga tttgtcgcaa atctttttca
     4801 cgaacatctc cgatggcaaa aacgcctggc atattcgttt tcatttcgtt gtctgttgga
     4861 atccagccag cttcgttcgt caaacctgct tctctaaaag gtgcagttaa tggatccagt
     4921 ccaacataga tgaatactcc gtctgctgct aaatcaaatt cattgccggt tttgacatta
     4981 cgtgctttca cacctgtcac taccatttcg tttccaacga tttcgtcaac gactgtatcc
     5041 cacataaagg aaattttttc atttgcaaat gcacggtctt ggatgatctt ttgtgcacgt
     5101 aattcatctc tacggtggac gatcactact tcagaagcaa attgtgtcaa atagatggct
     5161 tcttctactg ctgagtcccc acccccgatg actactagac gtttgttacg gaaaaacgca
     5221 ccatcacaga ctgcacagta agaaacgcct cgtccagcaa attcttcctc gccaggtacg
     5281 cctaatttac ggtggataca gcctgttgcg ataatgactg tttttccttc gtaactttta
     5341 tcttcacaga tgacttcttt atggctgccg tgatccttga tatcttgaac gattccataa
     5401 gcattttctg tcccaaatct tgagacactt tcatacatct tataagctag atcggggccc
     5461 atgatcgaat cgaatccagg ataattttcg atttctgccg tattgttcat ttggccgcca
     5521 ggggcacctt gttcgatcat caatacggat aagtttgaac gtgaagcata taaagcagca
     5581 gtcatcccag caggacctgc gccaataacg attacatcat acatatgtag attctccttt
     5641 acttaatcaa gtaagcatac tttacagcca atgcgaaaaa aagtctattg ttctgcttgc
     5701 gtttctcgaa tagctttatt atactcgaaa aatccgctga aaaacaatag acttttataa
     5761 atcattgatc aatcgttcga aagattttct ccatttgaat caattacttt tttataccag
     5821 ttgaatgatt ttttctttga acgggctaat gtgccatttc cttggttatc acgatcgaca
     5881 taaatgaatc cgtatctttt cttcatctca ccggtaccag ctgatactaa atcaatacat
     5941 ccccaagtcg tatagcctaa tagatcgact ccgtctagtt ctactgcatc cttcatcgcc
     6001 tggatatgcg ctgccaggta atcgattcgg taatcatctt ccacataacc attctcatct
     6061 ggcgtatcga ctgcacctaa gccgttttct acaataaata atggtttttg ataacgatca
     6121 taaatatcat tcatcgttat tctcaagcct aatggatcaa tttgccaccc ccattcactt
     6181 gcttgcagat atggattttt gacagaagca aagatatttc ctgcagtctg ttccaagagt
     6241 tcgttgtcgg tagtcgaaac tcgggaagaa taataagaaa aagagataaa atcaacagta
     6301 tgttctttca gcaatgcggc atcccctggt tccatttcga tctgaatgcc atttcgttcc
     6361 atttctttca atgcataagc tgggtattct cctcgtgact gaacatcaat gaagaaataa
     6421 ttttctcgat ctgattttct agaagcccaa acatcttcag gattgcaagt gtatggataa
     6481 tatgctcctg ctgccagcat acagcctact ttgttctccg gatctacttc atgagcaatc
     6541 ttcgttgcga tggcacttgc aaccaactca tgatgtgccg cttgatattt gacttgttct
     6601 tcgttttctc cttcttcaaa gtacagtcct gctcccatga atggtgcatg aaggatcata
     6661 ttgatctcat tgaatgtcag ccagtatttg acaagtcctt tatatcgatt gaagatgact
     6721 cgacacagat tttcataaaa accaacgagt tctctggaac gccacgcacc atattctttg
     6781 atcaaatgca ttggacaatc aaaatgcgta atcgtcacaa gtggctcaat tccgtgcttt
     6841 tggcattctt taaagacatc ctcataaaat ttcaagccag cttcattcgg ctctttctca
     6901 tcccccattg gaaaaatacg actccaggcg atagacattc gataagtctt gaaccccatt
     6961 tctgcaaaca aagcaatatc ttctttataa cgatgataca tatcgattgc aatttttgct
     7021 ggataaaaat gatcctcatc aaattcaaac atttttttct ttccggtgat aacaggaaaa
     7081 cggtcttttc cgattggcac aacatctacg tttgctagtc cgcgtccacc ttcatcataa
     7141 gcgccctcac attgattggc tgctgtagca ccgccccata aaaaatcttt tctgaacccc
     7201 attatacttc ctccattata tgtgtattac ctgataattc tcttgccagt tcatcttgaa
     7261 cttcgattcc ttcttctttt aatcggctga ttgtttcctt gaattgcggt aaatactgct
     7321 ggtgtgcaat aaacaactca tccatgatcc gttttgctgt ctttcctgat cgtataagtg
     7381 gattgatcgt aaacgcctgt aaagctgtcc cataatcacc agtcacagct gcttcgatcg
     7441 tcagcaattc catattcttc attacttgca accagcctct ttcagcagca ggaagagaac
     7501 caaacgctac atttctcgct ccttgtgcgc caacataggc agtgacttct acaacacaat
     7561 ctgccgacag gtcaggaaca gctccatcat tctttgtaga tacaacgatc tgtgtttctt
     7621 tatttccata gattgaagca atcgtttcac aggcagcgtc tgaataataa gcgccacctc
     7681 gtttttgcaa ttgttcaggt ttatggtcta attctggatc tttgtataat tcaaatagct
     7741 ctgcttctgt ttctttcact tgctgcgctc ttgtaccaat cgtttgatat tcttctaaag
     7801 catgttccag catttcttct tcacgatagt aatagcggtg gtagccacaa gggatcatgt
     7861 tcatttgttt taattgttct ttgaaaaacg ggatatcaaa gatatttttc ggtaatccat
     7921 tatcttcatc gtataaacga tcaatcaatt ctgccgtgcg gtcatttcct ttattatctg
     7981 ctactttgtg ccaatggaaa tgatttagac cggcaaactt gtagatcagc tcttcttttt
     8041 tcttgccaag cattgctggt tctgtcatca tcgccatcac tggcacattg cataatccaa
     8101 tcactttatc ccatttgcca tatctgataa ctgcttctgt caccatccca cttgggttcg
     8161 cgaaattgat cagccaagca tttggacata aacgcttcat gtcctcaacg attgccaaaa
     8221 cgactggaac ggtacgaaaa gctttgaata tcccgccagc accatttgtt tcttgcccaa
     8281 tcatcccata ataactaggg atccgctcgt ctttgattcg tgcatctaat tgaccgacac
     8341 gaaactgagt cgtaacaaaa tccgcatctt tcaatgcttc ttcccgatcc agagttgcat
     8401 agatcttgac ttcatatgga gaagcatccc acatacgctg agacatctga ctaacgatct
     8461 caagcttttc ttttccttct tctacatcta cgagccagat ttctcgtatc ggtaattcct
     8521 catatctttt gataaatcct tccatcaact caggggtgta actgctgcct ccaccaatcg
     8581 tagcgatttt gattcctttt gccatgttct cactccttta cttttttaca ctttcattat
     8641 cttttttgta aacaaaacaa acaatagaaa tccgtttctt tccagtaaca tttacaaaag
     8701 ttactgtttt ctagtggatt tttgtaaata tcttgtcaaa aaaagcctat tttaagttat
     8761 atagtataaa tccgtttaca aaacattttc aaaaaagtta taatttacgt aaaaaaataa
     8821 gaagaaggta tctacatgtt attacgtgaa aaaatcaaag aaatctcctt ttctccttca
     8881 gaaaatgaag tgatccagtt tctcttaagc gattctccag cacttggcga aatgaccatc
     8941 caagcgatag ctgagcgatg ttatgtccac ccgtctacac tcatccgtgt agcaaaaaaa
     9001 atgggttttg atggctgggt cagttttcgt aatgcttttt tagctgaaac agcctatctt
     9061 gaagggaatt ttcaagacgt agatgcgaat cttccttttt ccaccacaga cggtattatg
     9121 acaatcgcaa ataaaatggc ttctttagaa cagatgacga ttcatgatac actttctctc
     9181 attcatcatg accaactgca aaaagctaaa tatttactgc tccaggcaaa aaaaatcgtg
     9241 atcttcgcca gtaactcgaa tactttgatt tctcaagatt tcatgctgaa aatgaagcgc
     9301 atcaaaatgg atgtcacaat tgtcaccact tttggtgaat cattctatga agcgtacaat
     9361 tgtacgagcg atatgtgcgg gattctgatt tcttatacgg gtgaaaacaa tgtgatcctt
     9421 cgtaccgcag aaatattgaa acaaaatgat gttccaattt tagctttgac cagtatcggt
     9481 gattcaacgc tatctgcaat gagtacagcc gctttgcgac ttacgacacg cgagcgactg
     9541 tattcaaaaa ttggtaattt tacgatcaat acatcaattt gttatcttct agacgtgtta
     9601 tatagttgtg tttttgcaga aaattatcaa cagaatttag tccatctaat ttctgtcggt
     9661 caaaaattcg ataaacgccc tatcagctca gccatcatga aagagccttt caattttgaa
     9721 aataaagaag tggaataaaa agaatagtta agcctagtcc attcttcacc taaccgttca
     9781 ggtcagtgcg gtgataagtg catcgtctgg cccgaccgtc tccccttggt tttccaaaat
     9841 atccaaataa tccgtgtaat tggtgacgat cacaggtgtt tctaaactgt atccttcctt
     9901 ttcgattttc tttttgtcga agcgtagcaa cagatcgcct tgtttcactc tttctccttg
     9961 ctgcactaag ctttcaaaat atttcccttc caactgcaca gtatccaatc cgacatgaat
    10021 cagcaattcc agccctgttt cagaaaccat tccgattgca tgtttcgtcg ggaacagggt
    10081 cataactgtt ccgtcaaaag gggcacgtac ttctcctttt tcagggtaga ttaagattcc
    10141 tcgacctagt gttccttgtg caaaagctgc atccttcgct gcatttagtg gagcgatttg
    10201 tccttgtatc ggtgttttta caatttcttt acctgatttt ttctgtatag catctgtttc
    10261 acctgcttca tccttccaaa agaaaaaagt cagcgaaaac ccgattaccg aagcaatagc
    10321 aatgccgata aacgcttgaa acataccact ggcgtctgtt tccgtgatgt agtttaccac
    10381 cccaaaaatc cctaatccgc ccattatgta gctgattgtt ccagatgcca tcaaatagat
    10441 tcctgaaaca gcaccaccaa tcatcgagta aataaatggc ttcttcttcg gtaaggtgat
    10501 tccataaata gccggttctg ttacgccgaa gattcctgaa atcacagctg gcatgcaaag
    10561 cgccttcatt ttttgatcct tgaacttgaa atacatcgcc aataccactg ctgtctgtgc
    10621 aaaactcgcg ccataaacgc ctactaacat ctgactccac ccattttgcg ctagctgcat
    10681 aatcgcaaga gggataatac tccaatgaag tccgaaaatc accagtactt gccaaagaaa
    10741 ccctagaact gcaccataca cagctggaga aaagtccatc aatgcttgga atcccgtgct
    10801 taatagatct gtcagtatac tgacaatcgg accgataatc aaaaagccag caggaagtgc
    10861 gattaataac acagaaaaag aaaccaaaaa ggtctggacg actgcaggaa tccatttctt
    10921 ggcaattttt tggacttgtc cggcaaatgc gataatgaag ataacaggta cgacgctact
    10981 agtataactg ctgcccaccc atgggatacc caaaaatgtt tcataagccg gaagacccag
    11041 caagctataa ggcgcaggac tgccatcagg gaaaccactt tgtagtgctg ctccttgtac
    11101 agtcggataa caaagtgctg caccaatcac gagccccacc atcggattca gatgaaattt
    11161 tttcgctgct gtgtacccta agatcactgg catgaaataa aaaattgcat cccctatccc
    11221 attcagcatg atgtacgtac ccgatccttc agtataaaat ttgagaaaca agaacaaagc
    11281 atttaatcct ttgaccattc ccgctgcagc caaagcacct aaaaaaggct ggaaacagcc
    11341 acttaatatg tcgattaatc gattgaacag attactactt gaagaaacct cttcttctgc
    11401 ttcatcggaa atcccggcta ctgtcagtac ttctgcatag acatctggca catgattccc
    11461 gattacaact tgatattgcc cgccgctttt catgatggtg actatccctt ccatcttttt
    11521 caaaacatca tcctttgctt tattttcctc ctttagtttg aaacgaagtc gcgtcacaca
    11581 gtgtgtcaag ctacggatat tttcttttcc tccgatattc tttacgatgt tttctgctaa
    11641 ttcctggtat tttcccattt ctattccctc caattaatta gtggaaggtt tagccaactg
    11701 aatgtcacta cccttatttc atacgttctt gttaatttgt cctccttttt tatttattta
    11761 caacgattct catgcactaa acgcgcagta tggatcgtta aatacatttt ttcatccgtg
    11821 gacatctggt agtcgaaagc cccggttaaa aagtctgcta ttttctcaac gcaaccaaac
    11881 gtatccttat attttttttg aataacttgg aacaattcct cagaaacttc tccatcttct
    11941 gatttcgctc catctaggac acgtgtcaga aaaaaacgca ggtgtgtgac gaatcgaaaa
    12001 aagtggactg aatcttcatc aaatgtaatc ttatagtaat agcggacgat atttaaaata
    12061 tcctgtattg ttgtggtaaa caggtaggta ttgtcttgct ggctttgaat gccttgtgca
    12121 ttgactaaat gcaatgcgat aaatccggct tcgtcttctg ataacttgat gtggtattta
    12181 tccgagattt tcttcactgt ttttttccca atggcatact ctttaggaaa cagttgtttg
    12241 atatcataca gcaatacatt tggcacaaag atccccattt tttgacgttc gatagctgta
    12301 tacaagtgat ccgtcaatga aatatacaca gaatcattta aatggacttg cagagcctct
    12361 tttgtatatt caatgatttc acaagaaatt tctaagtact caagaggaat cgcttgtgcc
    12421 aattcttgga actgttgtga aagtccgtca tttgtcaact gaaatttttt gtcgatgcat
    12481 gagtcaagaa tcgggtcacc caccttcttt ttgaatgcca atccttttcc catcacaatc
    12541 atttcccgat ctctttcatc ccttgttatt acgacgttgt tattcagtac tttctcaatc
    12601 agcatgtttt gctcctttcc atgatatata gggctgtatc caaaacaaaa agaaaaaccc
    12661 aaaaagccgt ccatgaaacc atgggagact catcaggttt agcttgcatc aggcaatcac
    12721 tatccaagtt gtatcgtttt ctttatatta tcgaaagcaa acgattttgt caacgctttc
    12781 ttaggggcta ttaggcactt ctgactagct gacgtcgtct tttttaaatc tggtaactac
    12841 gacactaact ctcacagatg aaaaatatgg gaagctatgt tttattttca ctctagtgct
    12901 taggtcaaaa tgctactgtc acaacatctt ttatatacca ctactttgca gtttgtacat
    12961 atctgcatac aaaccatttt gcgctagaag tgtttcatga ttcccgcgtt ctactatatg
    13021 acctttgtct aaaactaaaa tcaattctgc atctcgaatc gttgacagcc gatgggcaat
    13081 cgcaatcgtt gtccgtcctt gtcgcatttt cgccaatcct tcttggatca atccttctgt
    13141 ttcagtatcg atatttgctg ttgcttcatc caatactaga attttaggat cagtcacgat
    13201 tgttcgcgca aaagtgatca gctgtcgttg tccactagaa tagctggcac catgttcgat
    13261 cacttttgag tgatatcctt ttggtaattc atcgatgaat ttgtttgctt gaacaaactc
    13321 agccgcatgg cgtatctgtt cgtctgtgat agctggattc atcatccgaa tatttcctgc
    13381 gatatcccca taaaacaaga aagcatcttg caagaccagc cccattttct tacgtaactc
    13441 ttccattgga tattctcgaa tgtcatgatc atcaatcaat atctgacctt cataaaattc
    13501 gtaaaaccgc atcaacacat tgatgatcga gcttttccca cttccggtgt gtcccactaa
    13561 tgcaacggtt tctcccggat tagcaacaaa agagatattg tttaatacat tgtgctctcc
    13621 atcataagaa aagcttacat tgcgaaactc aatcttacct gaagtaatca tttgatctgc
    13681 tccagggttt tgttgtggtg catattcttc cgtatccata atcttcaaga tacgactacc
    13741 agcaaccatc ccatctgtga agatgctcaa aaagtccatc atttgagaca ttggattaaa
    13801 aaatccctgg acataagtcg taaatgcata gatcagtcca acttctacgg gagaatgcaa
    13861 cgcatcgatc ccaaataaag tcaacgccaa cgcaatcgcc aatgcatata gaaaattgat
    13921 gatcggactt aacagaatcg aattcgtttt gatcatcgca tagcgcgtgt ctaaatactc
    13981 attgttcact tgttcaaatt ctttagctaa acgagcttct tggcgaaact gctggataat
    14041 acgcatgccg gaaatcgatt cattcaattt tgtattcagc tgacttaatt tttcccgcat
    14101 atttcggtaa atacgagaac taaatttctg gtaataccag atgacaattc ctaaaatcgg
    14161 caagaacacc aaagtccaca aggcaatttc tccattgatt tgaaacatgg caatgaatga
    14221 agaaacgact gcaaagatcc cagtcaatac catcaaaaag acgtaccaaa attcaaatag
    14281 cgtttctgtg tcattcgtca ctcgagaaac ggttgatcct gccggtgtct gatcaaaata
    14341 acgcatacct agtgtatgca gcttttcaaa taattttacc ctaatatact gataggtctt
    14401 caatgaagcc atggaataca aataccattg gaaaaaccaa atgatacttt ttactaggac
    14461 tccaaataag tacataccag caaaaaacaa aataacttgt gtcgtagccg actgtttagc
    14521 cagatgatca tccataaaag tttggatgat ccttggcaat aggacattga tcacagacag
    14581 agcaaacgca aataagatag caacgatgaa cgttgttcta aaaggtttgg cgaacttcat
    14641 cagtcgtttg atgatctttt tctgttcttt aagtggaatc gattttgtcc attccgattg
    14701 ataattttca tccatcaggc ctcgcctcct tctatcttcg cttctaattg ctgtttctcc
    14761 cacatttgtt cataccagcc gcctagtgca agcagctcat gatgggttcc tcgttcaatg
    14821 attttccctt gatcgacaac aatgatttct tttgcatgca tcacgctact taaacggtga
    14881 gctgcaatga tagttgtttt ctcttttctt atttctttta aattatgcaa gatagcttct
    14941 tctgttttgg catctactgc agaaagtgca tcatctaata ttaataattc aggatttttg
    15001 atcaatgctc gagcaatcga aatcctttgt ttctgtccgc cagataaaga gactccacgt
    15061 tctccaacta aggtatcata accttttggt aattccttga tttcattgtt gataaatgct
    15121 aaagaagccg catgctctac ttcttcttct gaaagttttg gattagaaaa acggatatta
    15181 tctcgaatgg tcatcgaaaa caagaagtga tcctgaggca catagccgat tgatcctaat
    15241 aaagcattca atgaatattc tttgatcgaa cgtccgccaa attggatttt cccttgataa
    15301 tcatcgtatt cacgcatcag taatttgatg atcgttgttt ttcccgcacc agttttccca
    15361 acaataccta atgtttctcc ttcttggatt gcaaacttga tttgttctaa tgctggtgat
    15421 tcttctttcg gataattaaa agaggaaata gctacattca gctcgccttt tgccggggtc
    15481 tgcactgcac ccagttgttc cacgatatgc gttttttcat gcaaaagttc attgacgcga
    15541 tcataagaag catttcctct ttccaatacg ttgaacaatc gaccaatcgc aaacatcggc
    15601 caaacaagca taccgatata actaataaat gagaccatct gcccgatcga gatcgtgcct
    15661 tccaagacat actttccacc taaaataatt gttgcaacat aagacagacc gataatcaag
    15721 gtaatgaatg gatcaaataa ggagtctaga aaattgactc gtttgttttt aataattgca
    15781 tcttcaatct tttcttcaaa atccgctaga tcttcttttt cttgtccaaa tgttttaatg
    15841 actttgatcc cagtgatact ttcttgtgtc ttatcattga tactagaaaa agcttcttgc
    15901 gaatcacgaa aagcatcatg gagtttcgac cccagcactc gtgaagtgac ggccagcaaa
    15961 ggcagaggaa tcagcgcaat cagtgttaag cgccaatcaa taaacaaaat catcgcaatg
    16021 atcgttgttc cgcccgtaat cactgaatct gcaaaggtca agataccagc tcctgctaca
    16081 ttctggatcg cattcaaatc attcgttgca tgagccatca aatccccagt ccgatatttt
    16141 tggtaaaaga gattgtccat ttttgtaaaa tgtttgaata actgctgccg aagttctttc
    16201 tccaaccgag ctgcacttcc ccaaatattc gtccgccaga tataacgaaa aagatattgt
    16261 aagaaagcag cgataatcaa taggaagatc cacccgaaaa tgatctttac tgataaattt
    16321 ttatcggcaa tctcatcaat gatgatccca atcacttttg gaggaactaa ctgtaccaag
    16381 gccactgcga atagcgagaa aaccccaatt aaataatgtt tcttttcctg acgaaaaaac
    16441 cagcctaact ttctaaaaat cgacatttta ctcctccttt gtctttatca agagcctagg
    16501 attgtctgtg cttgtctttt tgctgaataa tctgaatagt ctaacaaatt acaaaataaa
    16561 aaacggactg aaaaaatcag cccgtaaaaa gtcgttgggt cagaacctat tttttccctt
    16621 ggttcttcat ttgctgcatc atctggcgaa ttttcttctc agatggtttt tgtcccattg
    16681 acatcatcat tgatcgcaac atgtcctcat taacgggagg atttttttct aaatagtctt
    16741 tcatatattt acgcgctagg aaaaagccac ctactgcgcc gattagcaaa gcaataatag
    16801 caataagtac gacaatacct gttgataaca tataaatctc tcctttctat ttccgaattg
    16861 ctctcaatga cttattttac taaagtttat tgaaaaaaga aaggcgtatt ctttagtttc
    16921 atgcaaaaaa tagtggtttt tttagaggag aacaaaattt ctttcgtcat ctagcaagac
    16981 gagccacaaa aaaaaattag gcataccgaa tatttttctt taattttttc tttttgaggt
    17041 gtagaatgta atcgtagata aataggaaag gtggtttttt cttgaataat caatccaata
    17101 aacaatttca taagcatcga cttattgaac atacaaatgg tttatcttta gctgaagtaa
    17161 atggaacagt tgatgtacca aaggggaaaa gtttttttaa aacacttctt gcttactctg
    17221 gaccaggtgc attagtagca gttggttata tggatccagg taactggtcc acttcgatca
    17281 ctggtggaca aaatttccaa tatttattga tgtcagttat tttgatgtct agtctgattg
    17341 ctatgctttt acagtatatg gcagcaaaat taggaatcgt aacccaaatg gatttggccc
    17401 aagcaatccg agcacggaca agtaagacat tgggtgtcat tttatggatc ttgactgaat
    17461 tagccattat ggcaacagac atcgcagaag tcattggtgc agcaatcgcc ctctacctgc
    17521 tctttgatat tccattagtg attgccgtct ttattactgt attagatgtt ttcgttctct
    17581 tactactgac aaaagtcggg tttcgtaaga tcgaagcact ggttgtctgc ttaattttcg
    17641 tcattttatt cgtttttgtc tatcaagttg gcttgtctaa cccagattgg cacagtttat
    17701 ttgctggctt tatccctaac agccatacat tctccgactc acctgtcatt ggtggcgaaa
    17761 ctccgctgac tggagcttta gggattattg gtgcaacagt catgccgcat aacttatatc
    17821 ttcattcagc agtttcacaa actcggaaga tcgatcacca agacgaagaa gatgtagcac
    17881 aagctgtacg tttttctact tgggactcta atatccaatt gtcgatggct tttctagtca
    17941 atgcgctgct attgattatg ggtgtcgctg tcttcaaaac cggttctgtt caagatcctt
    18001 ccttttttgg tctgtatgaa gctttatctg atccatcagc tatgagcaat ggtatcttga
    18061 ttgctgtagc aaaatctggt atcttgtcca ctttatttgc tgtagcactt cttgcttctg
    18121 gccagaactc tactattact ggtacgttga ccggtcaagt catcatggaa ggattcatcc
    18181 atatgcgtat cccgatttgg ctaagaagac tggtcacacg attgctttct gtgattcctg
    18241 tattgatttg tgttttgttt acaagtacaa aaggaacgat cgaagaacat accgctttga
    18301 ataacttaat gaatgaatcc caggtgttct tggcttttgc gttgccgttt tcgatgatcc
    18361 ctttactgat gatgaccaac agccaagcgg agatgggtag ccgatttaaa aattcattca
    18421 tcgtaaaact tcttggctgg ttctctgtga ttagtctaac ttacttgaac ttacgaggat
    18481 taccaggaca gatcgaaagt ttcttcggcg agcaagccac ttccgctcaa ctagcattgg
    18541 ctgatcacat cgcttatgta atcattgttc ttgtccttct cctgttggca tggacgattg
    18601 gtgatttata taaaggaaac aaaaaatatg aacagcgttt gcaggaaacg gtagaagaaa
    18661 tcgaataaaa actgattttt ccacacaaag acccttgata gttaggttaa aaatctagct
    18721 accaagggtc tttttattta gaagataaag cttttttcag atttaattta ctgaaaacta
    18781 gcatgcttgt tactacgatg aattgcgtta acggcacgcc tgcgccagtg tagacactta
    18841 aaaaataatc ctttttttct ggcgcataag aacaaaacca cgagacaccg aaaagaaaaa
    18901 ccaattgtgt cagtattaat ccggtgacca caatcaaaga ggaactataa taggcacgat
    18961 cagcttttgc aaatacggtt cctagtatca taagtaatat ccctgctatt gaagcaatca
    19021 gcacgggaat agccagaact tggtaaattt ttatgatgac attcgcgact tttgctgatt
    19081 ttgttaattg gaaattaggt gttctcggtt cattactatc gatccaattc tccattagcg
    19141 gaaggtttaa taattcttga gcctgtttga cttgttcttg cgttccgaaa ctataatttc
    19201 ctccttgatg gaaatcttta tatcgccatg cataagcgta tcctgattga aggaaatcga
    19261 atacgattgg cagatcactc atcgtctttc catctcctga tcccatcaga tagaactctt
    19321 ttttcttttt gatggttccc ttgtgatagg cttcttctaa ttcttggttg acttttttcc
    19381 aaaaatcatt ggtttctttt gcattgtttt ggtaataacc agattcgctt accacatctc
    19441 gcaatgccca aaagatgata tctccgggta attcttttac ttttccacct tgagtccacg
    19501 cgtgagtcgt atataattcg tcaatacggg tagaaacagt atggaatgta ggagatgcgg
    19561 ctaatgcttt atttagtgca gcatgtgaga cccatatctc actgttttct ttattcaagt
    19621 tcgtttcatc atctattcgg atcagttgtt tcatcaaaca tccaaattct ccactggaac
    19681 ggtcattgat ggttgcaata ccgtatgttg tctcattttt atattcgatc cactgataga
    19741 cgatggaaaa gccaactata ggaagtaaaa acaatgaaag tttcagccat tcccgtttcg
    19801 agagaagaaa gagtcgtttt tttaacttct ctacttcttt gaaagaaaag tcttgcccta
    19861 gcaagatctg gacgaaactg atacccaaag ctactacagt aaaaggaaga agccagatag
    19921 aatcttcgcg aatgaaccaa aagaaaggaa aagcgacaga aagccctaaa aaccatggca
    19981 gcaattttct gctagaaccg tatttgcggt aataaatagc tagtaaacaa gcgataatga
    20041 tctcaacagc cggaatcacg agggcattac gatacgttcg agtggaatat tcatgtgtaa
    20101 aactaatcgg agaaaacaaa aaataaaaat agaaacttaa aagaagatac ttgttcttca
    20161 cgatcggttt aaacgcgagt gcaaccaata tactggcaaa aatactgaac atgccgaaca
    20221 aaactgcata agaaagatgc agtttatgtg caagtactaa aaataagctg taggagattc
    20281 ctttggaaag tgttgtagtc gtatactccc ctagccattt accgtccaaa atattttgag
    20341 catagcgaat cagcagctgg tcatcatagg ttgccgacat gtctgttcca tagattgctt
    20401 tactatataa atacaaacga ataattgtaa ataatagggc tatgccaaga ataaagtatg
    20461 tatgtttctt ttttagttgg ttgatcaagg gttttaaagt gttcagcatc ttttcgtcct
    20521 tccaatcacg ttttgccact tgcttgtgaa acttttcgtt tttttacttt tctaccagta
    20581 taccctgttt gtctaaattt aaaaagaggg gggagaagat gcatgatgaa aaagactgca
    20641 aaaagcactc ctttgtttct taaacaaaaa aggacaaggc aatgtgcctg gtcctttttt
    20701 gctgctgtca gatagaaaat cttagagtat cacttcttct gctaataact caggaaacac
    20761 ttctggatcg aatatttgtg ctttgaacat ggcgatttct tttccatatg gtgcgtaagc
    20821 tttcttttta tctttgccga catagggagt ttccaagatt ttcgaaatat tgtcaaacat
    20881 tggatcatgg acgatcttat tcagcgtgtc gaatccgatt gttccaaaac caatattggc
    20941 gtgccggtct ttatgcgaac cttgcggatt tttagaatca ttgatatgga gtactttaag
    21001 ccgatctaac ccgatgatct tatcaaactc ttccattaca cctgaaaagt cttctttaat
    21061 attataaccg gcatcattcg tatgacaggt gtcaaaagta acggataatt tttcattcaa
    21121 ttttactcca tcgatgattt gcgctaattc ctcaaatgtt cgaccgattt ccgtaccttt
    21181 acctgccatt gtctccaaag cgatttgtgc cgtctgttct tttgtcaaaa cttcattcaa
    21241 gccttcaata attctagcaa ttccggcttc tgttcctgcc cctacatgag cacctgggtg
    21301 aagtgtaatt tgagtagcgc ctaaagcttc cgcacgaaca atctcttctc tcagaaattg
    21361 gacggcaaaa ggaaacattt ctggtttgat cgtattcccc aaattaatga tataaggggc
    21421 atgaacgacg atatttgtta gaccgttttc tgccatgtac gcttttccgg catcaatatt
    21481 catctcttcg atggcttttc ttctagtgtt ttgaggggcg cctgtataga tcataaaagt
    21541 cgaagatcca taactggctg cttcttctgc tgctcctaac agcattttct ttccgctcat
    21601 gctgacgtgt gagcctaata acatggatgg attcctcctt gaaaggcaat tgttactaac
    21661 aattcctata tattggtaag atgatataca aagaaaatga ttgatttttc tttgccctgt
    21721 tctccatagt aactgaaatt ttctctaaag aaaagcttaa gaactctttt ataaaaaaga
    21781 tcattttctc acgttttaac tcctattatt tgtcaaatta ag
//
LOCUS       DAIGWC010000047        21582 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.048, whole genome shotgun sequence.
ACCESSION   DAIGWC010000047 DAIGWC010000000
VERSION     DAIGWC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21582
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.048"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            262..963
                     /locus_tag="NOB74_001803"
     CDS             262..963
                     /locus_tag="NOB74_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI1220991.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1572..2588)
                     /gene="tsaD"
                     /locus_tag="NOB74_001804"
     CDS             complement(1572..2588)
                     /gene="tsaD"
                     /locus_tag="NOB74_001804"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HCI1220992.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2585..3049)
                     /gene="rimI"
                     /locus_tag="NOB74_001805"
     CDS             complement(2585..3049)
                     /gene="rimI"
                     /locus_tag="NOB74_001805"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCI1220993.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(3056..3598)
                     /gene="rimI"
                     /locus_tag="NOB74_001806"
     CDS             complement(3056..3598)
                     /gene="rimI"
                     /locus_tag="NOB74_001806"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCI1220994.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3582..4304)
                     /gene="tsaB"
                     /locus_tag="NOB74_001807"
     CDS             complement(3582..4304)
                     /gene="tsaB"
                     /locus_tag="NOB74_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HCI1220995.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4495..5475)
                     /locus_tag="NOB74_001808"
     CDS             complement(4495..5475)
                     /locus_tag="NOB74_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1220996.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5499..6983)
                     /gene="galT"
                     /locus_tag="NOB74_001809"
     CDS             complement(5499..6983)
                     /gene="galT"
                     /locus_tag="NOB74_001809"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HCI1220997.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6995..7984)
                     /gene="galE"
                     /locus_tag="NOB74_001810"
     CDS             complement(6995..7984)
                     /gene="galE"
                     /locus_tag="NOB74_001810"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HCI1220998.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            8232..8399
                     /locus_tag="NOB74_001811"
     CDS             8232..8399
                     /locus_tag="NOB74_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HCI1220999.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(8461..10272)
                     /locus_tag="NOB74_001812"
     CDS             complement(8461..10272)
                     /locus_tag="NOB74_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HCI1221000.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(10269..10634)
                     /locus_tag="NOB74_001813"
     CDS             complement(10269..10634)
                     /locus_tag="NOB74_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HCI1221001.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(10797..11192)
                     /locus_tag="NOB74_001814"
     CDS             complement(10797..11192)
                     /locus_tag="NOB74_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI1221002.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(11210..12172)
                     /locus_tag="NOB74_001815"
     CDS             complement(11210..12172)
                     /locus_tag="NOB74_001815"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HCI1221003.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(12172..12384)
                     /locus_tag="NOB74_001816"
     CDS             complement(12172..12384)
                     /locus_tag="NOB74_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HCI1221004.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(12405..13103)
                     /locus_tag="NOB74_001817"
     CDS             complement(12405..13103)
                     /locus_tag="NOB74_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HCI1221005.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(13123..13665)
                     /locus_tag="NOB74_001818"
     CDS             complement(13123..13665)
                     /locus_tag="NOB74_001818"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HCI1221006.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(13797..14801)
                     /locus_tag="NOB74_001819"
     CDS             complement(13797..14801)
                     /locus_tag="NOB74_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCI1221007.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(14798..15787)
                     /locus_tag="NOB74_001820"
     CDS             complement(14798..15787)
                     /locus_tag="NOB74_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCI1221008.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(15784..16590)
                     /locus_tag="NOB74_001821"
     CDS             complement(15784..16590)
                     /locus_tag="NOB74_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221009.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            16756..17712
                     /locus_tag="NOB74_001822"
     CDS             16756..17712
                     /locus_tag="NOB74_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1221010.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(17789..18307)
                     /locus_tag="NOB74_001823"
     CDS             complement(17789..18307)
                     /locus_tag="NOB74_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI1221011.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(18395..18544)
                     /gene="rpmG"
                     /locus_tag="NOB74_001824"
     CDS             complement(18395..18544)
                     /gene="rpmG"
                     /locus_tag="NOB74_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI1221012.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            18772..19218
                     /locus_tag="NOB74_001825"
     CDS             18772..19218
                     /locus_tag="NOB74_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HCI1221013.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(19413..21308)
                     /gene="asnB"
                     /locus_tag="NOB74_001826"
     CDS             complement(19413..21308)
                     /gene="asnB"
                     /locus_tag="NOB74_001826"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HCI1221014.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         6505 a         4564 c         3710 g         6803 t
ORIGIN      
        1 gaaaaaattt ttttgaataa attaaaaaaa taaattatat tatcgttgtt agcgtttact
       61 atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa ttattcaata
      121 ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa acttgtttct
      181 aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa atatagtgaa
      241 caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt ttcaaaactc
      301 agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat caaggaacat
      361 actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga tcccagacaa
      421 cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga aagtgcaact
      481 tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg aatgtttgga
      541 gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt ctaccttcct
      601 gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta tatgatacaa
      661 aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt gacctctagc
      721 gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg cgtaccaaca
      781 aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc agtgaatagc
      841 ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc cgggctgtta
      901 gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc tatgagagaa
      961 taacgcgaac aaaaataagc agtgaccctg ataaatatca gggtcactgc ttattttcct
     1021 ccctaaaact tctgaaagat ccggcagttt tagatcactg gacaagactc aaagattttc
     1081 tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgtta gattaactag
     1141 atgaagcgtc ttgtcctcat ccgatctaga ttattcgata ttcctcgaca ataaacgatt
     1201 actcagtgag ggcaatcaga ggaacggata atgataaata agctgtaaaa aatagcaaaa
     1261 taacaataat gattaaaagt atgtaaaaaa tagggctttg acaaaaacgt gtcacagccc
     1321 tatttcgatt aaacggtgtg tacctgtcaa ctcttcggtc acaagtcata atgttcataa
     1381 acatgaggag ctgttttttg aaattgttcc ttgtgaatca gagttaaacg acaggcttac
     1441 gaactcttga ttaaacggcg ttcaaaagct tgcatacgcg gtaataagaa cagccaggtc
     1501 aaaaacatga gaagccgttt ttcctgggct gttcttatta cttgatgcag ggcagctttt
     1561 tcacaacctc tttattcaga taaaaccaag cttggatcag cattcaactg atagctagca
     1621 aaatttcttt tttgcatttc cacatgtgct gctgctccaa tcattgcagc attatctcca
     1681 caaagtcgaa gagggggaat cactagttct acctcaggga gtttagctgc caaagcatcc
     1741 tgcaatcctt cacgcaaccc ttgattggcc gctacacctc cagctataat cagttgcttg
     1801 actggataat tttgacaagc tcgaagtgtt ttagtaatca atacatcgat cacacttgct
     1861 tgaaagctag ctgctaaatc atttttgtct agatcttctc cacgctgttg tgcattatgc
     1921 accaaattga taaatgcact ttttaatccg ctaaaactga aatcataatt atcttcatgg
     1981 atcatcgctc gcggaaaatg gtaattatct tttccctgat gagctagctg atcgatttct
     2041 tttccgcttg ggtaagaaag acctaatact cttccaactt tgtcataagc ttctcctgct
     2101 gcgtcatctc ttgtctcccc aatgatttca tatgatccat cttcttgcat atagactaat
     2161 tctgtatgtc ctccgctaac aagaagtgcc atcaatggaa actggaatgg tttaaccaga
     2221 cgggctgcat agatatgccc tgccatatgg tttacaggaa taagcggcaa ttggtgtgcc
     2281 caagcaaaag ccttagctgc agaaatacca atcagcaacg agccgacaag tcctggtcca
     2341 taagtgacag cgactgccga taaatcttct gccgacacac cagcttctac cagtgcatct
     2401 tccaagcata aggtgatttg ttctacgtga tggcggctag ctacttcagg tactacgcca
     2461 ccaaaacgtt tatgactgtt tatttgagaa gcaacgatgt tagataagat ctctgttcca
     2521 tttctaacga ccgctacact cgtttcatca caacttgatt caatcgccag aatcaattct
     2581 tcattcattt catcgtctcc gtttttaact ttctgctcat aatgatcgca tcttccgtcg
     2641 gattgcgata atatgatttc cgtttaccta atatacgaaa cttttctgat tcataaagtt
     2701 ttcttgctgc ttcattagat agacgtactt ctaaaaaaac atgcagcgaa tcttttattt
     2761 gttccgtaat cagtaattgt aacaaatgcc gtgcatgccc ttttccttgt tctgaaactg
     2821 caacagcaat atttgtgatc tcgacttcat ctattacttt cgagtatcca ataaagccac
     2881 agatctggtt atcttcagct aaaagcagat aatcagagtg aggctgttgg atgtctgcca
     2941 aaaactgcat tttcgtccaa ggtgaaccat gtggataagc attttcgcta atcatccata
     3001 cgcattctgc caagtacgct tcatcaaaat ctttttttct gcaaatcaac taatctcact
     3061 cattttctaa aagttttatc atatccaacg catcttcttt tgtttcagtg taatatcttt
     3121 ttttgatcgt tgttgcttga aaccccaatt tccgataaag tctttgtgca tcttgattac
     3181 tcatacgcac ttctaatgac atcgtctcac agcgattcat tatagcaaag ttctcgattt
     3241 cgtcaataag cagcgaaccg attcgtttac gctgatatgc cggtcgaacg gcaatattcg
     3301 tgatatggca atctaaaccg aacgctcttg aaccgataaa accaatcatt cttccattat
     3361 caaagatacc tagatataga tgaggaagcg gtgacttcaa ttctgatata aaggcacttt
     3421 ttgtccatgg caattcgcca ttatagactt ctcgttcgac atccagcagc tctttgatat
     3481 cttctgtagt caattctctt agtacgtaac gacgatcgat ttgttcgact gttttttctg
     3541 tataaatcat tttatcttga aaaaagcttc tggcatacgc tctaaatttt ttcaacataa
     3601 ctttcgtctc caggtgtgtg cgtctccaac catttttctt ctgcttctac tcgttttaaa
     3661 tagcgaggaa gaaaagcttg tttctctgca actggttcaa ctaaagcacc taattgagcc
     3721 acagttacac cacttggaat atcccatgct ggaactgtat taatcatcgc actaggcaat
     3781 atttccttta tttcagagaa gaatttgtga caatcactcc cgacgaaata aatagcttca
     3841 ttcagctttt gtagttgtgt gaacaaatca gaagcagaaa tatgtacatc ttcaagtaca
     3901 gtttctaatc tattttcttt ccagcggtat gccccagcgt atacattttt tcttcgagca
     3961 tcaaacatgg gcacaataat attatccaca ccgatgcaat tagccgcgat ggttttcaga
     4021 ctagatactc ctactagctc tttatctaat gtataagcaa tcgtttttgc tgtcgttaca
     4081 cctatacgaa gccctgtata agaaccggga ccatcagaaa ccgcgattcg gtcaatgtct
     4141 tttggactta tttgaagatc tgcaaacaat tggtcgattg caggcatcag tgttacactg
     4201 tggttgcgtt tgatatttgt ttgtatttgt ccaagaattt gttcgtcttc taccacaccg
     4261 atcgccaaag tttggtttgc agtatctatt cctaatgtaa tcatatattt gatcctttct
     4321 gctatgacat tctcgccttc cattgtagca tactttttta ttctgaggat gaaaatacca
     4381 aaggcaaaac tagtacaata atacatgatt atctgctggc gggcaaattt tgccccttcc
     4441 tgaaacacaa aaaagctgcg gtatcactcc attttcccac agcttttcca tcttttattt
     4501 cgttgattct cgaataatca actctgtttc cacaataatc tttcttgaaa ccggtgcttt
     4561 ggaattactt aattgaagaa tcgtctccac tgctagctct cccatccatt cggtataaac
     4621 ttttacagta gaaagcgagg gcgttacata tttcgctaca ctgacatcat tgaagcccat
     4681 cacagaaata tcttctggta ccactaaacc tttttcttga atcgctttca gtgcgccaat
     4741 cgctaatgca tcattagctg caaaaagcgc atcaggaaca tgcggattcg tttttaaata
     4801 ttgcttcact gcttgatatc ctgactcgac agaaaaatct gcttcgataa ttggaccttc
     4861 gtcgtagcct ttttctgcca aaacttgttg aaatgccata attctgggat cttttagccg
     4921 ctgatggttt ttcttcgtat attctgttcc agcaagcata gcgatatgtt gcgctttatg
     4981 ggagacaaag tgttcaatga ctttttgaac acttgactta aagtcgacaa ctagagagtc
     5041 gattccttga gaagtgccgt cagaatctac caaaagcaag gcattttggg atcctttcat
     5101 ttctaataac tgagcttcgt cgaattttcc tagtgcgatc gttccatctg ccggaagatc
     5161 actaatggaa tcccacgttt ctttcaataa agtaacgttt gcttcttctg cctttttttc
     5221 gattcctagg cgaatagata aataataaag atcttcaagc tcttccgtat cgtcgtacca
     5281 ctggatcagg cgaagcgttt gcttagtatt tgctgcattt ttacgatgtt tcgtataatt
     5341 taagcgttct gctgcttcaa aaattttttg ctttgtggct aagccaacgg aaagatcagg
     5401 atcatagttg agaactcttg aaacagtagc aggagaaact cctgccaact gcgcaatgtc
     5461 tttaattgtt gccatttgtc tctcctcctt ttttacgttt ataaaatcgc agtaaatcgt
     5521 tcaaacgctg cctgtccttt ttcatctcgc ttgaatactc cagcgtcttc cagtacacgt
     5581 gcaaaaacct gacctacaga tttttgtacg acatcggtga ccgtatcttt cgtcaaatca
     5641 ggatgttctt tttttaattg ttctgcccac ggacgatgat attcagccat ctggttttct
     5701 tctcctaata agaaatgctc tacttctact agttctggtt tcaaacgagg tggtaaaaca
     5761 gcaagcccca ttacttcgat caacccaatg ttctcctttt tgatatgttg gacatcttta
     5821 tgtggatgaa aaatcccatc aggatgttct tctgaaacat tgttgtctcg aaggacaagg
     5881 tccaactcaa agtaattgtc ccttcttcgt gcaattggcg taatcgtatg gtgtggtgta
     5941 ccatctgctg aaaaagctct gatagatact gtttcatccg aatatgcttt ccatttttcc
     6001 aatactgagt tagctgcttc aataagcaag tttttctctg ttgattgcaa acggatcaca
     6061 gacatcggcc atttcacgac tcctgcgatg acttgcggat aatcttctag tttgataagt
     6121 ttttctatcg gtgcttttgc cataggaaat tcatgacgtc ctgcctgata atgatcatga
     6181 gaaagaatcg atcctccaac aattggtaag tcagcattcg aaccaacaaa gtaatgaggc
     6241 aagacttcag taatccgaag cagtctagca aatgtttcct ttgtgatttt catcgggcgg
     6301 tgttgttctg ataaaatgat cgaatgttca ttgtaataag cataagggga atattggaat
     6361 ccccagcttt caccgtctag attcattcga ataatccggt gattggtgcg ggctggatag
     6421 ttcaagcgac ctctatatcc ttcgttttcc atgcaaagca tgcaggtagg atagtctact
     6481 tttaccgcct cgcgttctgc tgcgatttgt tttggatctt tttctggctt agataaattg
     6541 attgtgattt ccagttcacc atactccgac tctgccggaa atttgatgtt ttttgcgatg
     6601 gctcttgttt tgatgtagtc atttttctta cttaaattaa agaaatactc agttgcttcc
     6661 tctgggcttt tcgaatagtg ctgtgcaaag aatgcattga cgactgaagg tggcggtgtg
     6721 agaaaatcca ttaattgcgc ttcaaaaatc tcttgttctg ctggcaattc tgaaagaaca
     6781 ccattttctc ttgccttagc gacaagctga tccaataagt ctacagattc ttccttaact
     6841 ggtcttactt caatgctttc tagagcatct tctcctacca tccctaaaag acgattctgt
     6901 aaatataagc ggtccatttc catccatccg ccagcttcga tcgcaagtgt ggcaaaatca
     6961 caaatcgttt gactgattga catatctcat tcccctattc ttcataacca tttggatggc
     7021 tgacatgcca atcccatgct gttttgataa tcgctttgat atctgtgtat tcaggtttcc
     7081 agcccagaat ctctctcgct ttttcacttg aagcgactaa tcggctagga tctccagctc
     7141 ttcttggtgc tatttctgct ggaatttctt ttcctgtcac ttctctagct gcttctagca
     7201 tttccttgac tgagtatcct ttgctgctgc ctaaattgaa gaagttgctt tcatttcctt
     7261 ctttcaagta ttccaaagct aaaatatgtg cagcaatcaa atcttctact tgaacataat
     7321 ctctgataca tgttccatct ggtgtatcat aatcgtctcc ataaacagcc aaggcttttc
     7381 tttgaccaag agctacttgt aaaatgattg ggacaagatg cgtttctggt gtatgatctt
     7441 ctccgataga tgcatctgct tttgctccgg ctacattgaa gtagcgcaaa gcgacatagc
     7501 gcatgccata tgcttggtca caccacttca tcattttttc catcatcaat ttactttcac
     7561 catacggatt tttaggatta gctggtgtat cttctgtgat tggagactct ttcggctctc
     7621 cataagttgc tgcagtagaa gagaatacga ttttattcac gttgaactcg tgcatgactt
     7681 caagtaagat ttgcataccg tatacgttgt tgttgaaata catcaatggt ttttcgacag
     7741 attctcctac taaagagctt gcagcaaaat ggattactcc ttcaatcggt tccttttcaa
     7801 atacggaacg tagaaattct ttatcccgga tgtctccttc ataaaaatga gcatctggat
     7861 gtactgcttg tttgtgacct gtgagcaaat tatctaccac agctacttga tacccctttt
     7921 gaactagctg gtctacagcg tgcgaaccga tataaccggc tccgcctagt actaaaattg
     7981 tcataaaaaa cactcctttg attagtaaaa ttgtgtttgt tgattctata taatttaaaa
     8041 aacgaagttt acttttatgg tgaaaacaaa caaagtaaaa tttcgtaaat tcatatggta
     8101 aatttataat aaaacattta gtaaacattt tcaagggttt tttgcaaagg tttacaaaca
     8161 aacgtaaaac tagccttttt ttctcttttg ttccataata gatataacaa ataataaatg
     8221 aggtggattc aatgaaaaaa tttgtatctg gaatattagt aggaagtctg gcaacagccg
     8281 ctgccgttgc tggtttggtt gcttctgtga aaaaaacagt gatcgatcca attgacgaaa
     8341 aagaagcaat gatcgaagaa aaccgtaaaa aagcaatgcg taaacgcgtt tctcgttaat
     8401 aattatttaa aaatacgcat gaagactttc taaaaaacag ataagtcatc atgcgtattt
     8461 ttatttgtca gtcaatataa gttgtgctat tttatctgcc tgtctcagat tccatggatc
     8521 tgtataaggt ctagctactg ctgcagttag ccaatccaca ccttcaacag gtattccata
     8581 gcaataaaag tcagactgga tttcccctga agcatcaatc acgcgattcg tacctcgctc
     8641 aacatctata gcttctgaat gataacttcc tgtattatct gaaaatgaaa aagggcgaac
     8701 aagtttgttt tccttcaaat tttttatgac aggattactt gaacgagaaa agcttgtttg
     8761 tggcaatcga gcttcaatca aatagcgact gctgatttct ttatcttgta gagaaataac
     8821 atagcggttg tgcttttgct gaatatcaaa tggcggttcg atcaaatgaa aaatacccgc
     8881 atctatcagt gctgctaatt ctttcgtccg aatgattggc ggaccgatcg ttaaaaagct
     8941 atttagatga gtaaaccatc cccatagtat ttctttgtat tccttagcag aaaaaacgtg
     9001 ccattcaata gcctgccgga ttggatcacg ccagtctttt aatgcatcaa atgttgaagc
     9061 aaatgctcct gtgcaattgc ctttttccgc ttcttttatc tgcccttcaa taaatattcg
     9121 gctagcttct gaaaagggct cattctgata ggcaagagga gtttctaaat acgaccaatc
     9181 ccatctataa gggattagtg ctggatgctt tccgagacac tcctctgaag agagggagag
     9241 aaaatcatgc tcaaaatttt tctttggaat cggcaagtga tattcttcga tgattttctt
     9301 gtaataaaac aactcaacgt cttttttcag atagtcaaaa aatgtttcgc cagtcaaaaa
     9361 tcccgactga tgccattgct ccaggttttc ttttgttagt aaccgtggcc atgccattgc
     9421 tccgccttgc ttttgatttc ttcctcgagg gtaataaggg agcccccttc ttgatccact
     9481 gtatacaatc ggttccttgc ctgatggatg atagaccagt tttccctttt cgttctcgaa
     9541 gcgccctcct cttgatactg taaacaatcc gacataatca aaaaaactta agcctagacc
     9601 tcttaaaaag acattttctt taggcggtat cttcgaaaga tctacatctg caggattaga
     9661 aggaagctga tacagtaaaa catttttctt tgcgtagtct acccacactc tttcttcttc
     9721 tgtctcatca ttttcccagt gaccgcttgc taaaacaagc tgatcgatag aatagctttg
     9781 ctgatctgtc tgtaaaagat aaccatcttt tcttttgctt acttttttta ctaaagaata
     9841 aacaaactga atagaagctg gaaattcttc ttgcaacttt gagaaaaacc agcgttgata
     9901 gagtccgtat aaacatcgag tagattgctg atctttttcc agacgattga tttcttctat
     9961 aattagttgc ttatttttgg ttaccgtctg ttcgatataa tctgtagcag gtcctttact
    10021 ccattgaaac aagttgggtc cctgtgttac caatcctcca ctggacaatg tttcatctgt
    10081 aaaaagcgtc acttgttgag aaacagaatt cattaataac tccggtggct gattcaaccg
    10141 ccaaactcga cctccaggac cattgggatc gaaaagaaaa agttcaagag aatgtctgtc
    10201 ctgattatta tggagaatcc tttctgctac acttaatcct ctaggtccgg caccaatgat
    10261 ccctattttc atttgcatgc ctccatttcg ataaattttt tcaataaaac agcatggttc
    10321 tgatgttcat tttttgcacc ataaacaaaa gtaatgactg gatgttcttt cataagttga
    10381 ctgagtttaa aaatagcttg cttcttttct tcttcgaaaa tcaattcttg ctggtatttc
    10441 tttgcaaatg aagcaaatcg ttctggtaca tggtcaaaag ttttgcgtgc ttcattacta
    10501 ggtgcaattt ctttcaacca cagatctaac tgcgcttttt cttttgaaat tcctcgtggc
    10561 cagaatctat ccacgagtat tctatagcca tcctcttttt cagcatcaag gtaaacacgt
    10621 tttaatttga tcatagttgt ttccttcttt ctaccttttc gcttagctta tatatgtaga
    10681 taatagcaca aaataaaaaa aatgaacggc acaactatcc attgcgccgt tcatgtgatc
    10741 ttggtcaaaa tctaatgatt gattcggttt ttaaagctgt catacaatca tctgttttat
    10801 acttttttac ttttgatttt tccagaccat ccgtcatatc cacccttaag taaataaatc
    10861 tcttgataac ctgctttacg taatttattt gctgtacgga tgctcaaact tttcttttga
    10921 tcgtaaatat agacaggctg gtcttttcga atagatccta atgaatcttt caaaacagtg
    10981 taagggatgt ttcttgcacc taaaatatgc ccagcatcaa acacatcttt ttcgcgaaca
    11041 tcgattactt gtgcttttct cattccttct cgaaattctt cttctgtcaa agtcgttgct
    11101 gaacgtttgg ccattactcg tagatagact tcccaaagga tgattgcaag cacaatcaat
    11161 agcaaaatga tattaattac ccataaaacc atgtaatgcc tccgtttttt taagcaaatt
    11221 tcaaggctaa tgaggcagca ccaatgacac cagcttcatt accaagctct gctaatttga
    11281 tttttgttga ttctcttact tgcgggaaag taaattcttt aaaatatttc tctacacggc
    11341 tacgtaaaaa ttctcctgct gccgatactc ctccacctaa cacgatactt gacggattta
    11401 atgtattccc caagtttccg caagctaaac ctaagtagaa gcatacgcga tcaacaacca
    11461 tcaatgcaaa cggatcgtct tcttgagcca tttcaaagat atctttactt gttacttctt
    11521 ctccgttgtc tagcattgct ttcagttttg aatcccctgc gtattcttct gccaagaaac
    11581 gacctaggcg taccacacct gtagcgctag atacagtttc taaacatccg cgtttaccgc
    11641 aagtacattc gaacccttca ggatccacag tgatatgtcc gatttctcct ccagctccgc
    11701 tcacgccgtg aatcaaattt ccgccagcaa cgatacctcc gccaacacct gttcctagag
    11761 taacgaatac aacgtctgga tcgttttctc cagcaccttt ccatcgttca cctaaagcag
    11821 caacattcgc gtcattatcg atagcgaatt tgattcctgt tcctgcctcg atcagttttt
    11881 tcacaaattg aacttctgtc cagtttaagt tatacgcacc aataaccgtt ccagcttcgc
    11941 tgtccacgct tcctggggta cccatgccga ttccgataaa gtcttcggct ttcatattat
    12001 ataaattcaa acgatgattg attgattcaa tgatttcagg aacgatatgc ttaccatcat
    12061 ccaaaatatt ggtatcgatg ctccattttt gctgaatctc tccttctggt gttaaaattg
    12121 caaattttgc tgttgttcca cctaaatcaa tcccaataat cttcttgtcc attacaaatt
    12181 tcctttcttt cggctttctt caattcggtg ctctcttttt aatatgcgcc acgctgtcat
    12241 gtatgtatca tgatcaatca aacggctatc atacagatta cgcaattcga tagtcattaa
    12301 ttcaatgtca tagatgcgtg cacccacata gataaagatg ccaaattttt tgaacagctg
    12361 ctgtacatca tataagctct ccatctttaa gcacttcctt catattatac aagtaaacca
    12421 tattttttta aacccagtaa aatacatatt acaaaaagaa atacaaaaac tagtgtagaa
    12481 agaatccttt ggtgtatcga atagcttgtc tgttgtttcg gtagacccaa aacattccct
    12541 aacactaatc cgccaattag cccaccgaca tgtccccaaa catctacaga ggtatccaga
    12601 agaccaaaaa caaatgtcaa cacaataaat aaaagaaaat gtctgactag ctgctggatc
    12661 gctgggttat gtttaaaatg aaaccctaag ataaacaacg caccgaacaa accgaatatc
    12721 gaagtacttg caccaccaga cagaacattc gcttcgttaa aagcaaagct tgctgtattt
    12781 cccattatcc cgctgaacat ataaatcaag aaaaaacgcc aatggccata gattgcctcg
    12841 atttgctgcc ccataaaata cagtatcagt gagttcatta cgaaatgcat cagtccaaaa
    12901 tggatgaaga ttggtgtcac taaacgccac cattcattga agtgaacaag ataaggacca
    12961 tacattccgg cataataagg gatctcaagt cgcggaaata attccatcat gaggaagacc
    13021 gctgtctgta tccctaaaaa agcataggtc cataacggtc gtcttaacca tgcacgcaat
    13081 tttatttgct gttgataatt catgaaaacc tcccatttca ttttagtcaa taaacaattg
    13141 ttggatcttc tgatcaaagc tctccggttg ccattgttca ttcaattgtt cacgaaaaac
    13201 aaggctacat gtttttttat gaaaattatt taaataccgg tcgtaataac caccgccaaa
    13261 accgattcga taaccggctc tattgtagat aatacctggt acaatgagga gatcgatcat
    13321 ctccggcaaa tagagcttct ctgattgtgg ctcaagaaca ccaaaactcg aacgtacaag
    13381 aacggactgt tcatccattt cataaaacgc catctgacgt ttcggcaaag ttttaggtac
    13441 aactattttc ttttgttctt tttctgctcg ttggataacc ggctgtgtat ccagttcaaa
    13501 ttcattcgat aaagtcgtcc ctatcacttt tgctgacttc cagtactcgc tggcgaatag
    13561 ctgtttatag attcgctgtt ctttttcctt tttcttgcca cttttggcca gatttttcag
    13621 cttttcgatt cctttccggc gtaatcttac tttcaattgg tccaaaaact cacccttcct
    13681 tctctcataa aatggtatag gaaaaaaaga aaaatagcaa tcgaactttc aaataaatgc
    13741 ataaatagaa taaaaagaag acctagaaat gattggcctt ccttttttaa tgaatttcaa
    13801 ctgttcagcg cgtgtttttg tctgataaaa agtgcataca gaaaatatgg cgcaccaaaa
    13861 agggcaatca aaattcctgt aggtacttcc ccacttggta gaatcactct agcaaccata
    13921 tctgcactaa gcagaaaaat ggaaccgaac aaaccgctca gaacaaaggt ccagttattt
    13981 tctttacgta cgactagctt cgcagcatga ggagctagta gtcctacaaa agataaacta
    14041 cctgtcaccg ctacactacc gcttgccaaa gcaacagcta acaacaaaag gattttttga
    14101 cttttagcca cgttaaggcc taatccttgc gcgcgttctt gaccaaatga tagcaataca
    14161 atcctctgtg cataaagtcc tcctagcgga attaagataa ccgcccatgg aagcaatgcc
    14221 caaacataag gccagctcgc accccagatt gatcccgcta accatgcatt cacaaatcca
    14281 taattttcct tagataattg gatcgtgcat agcaatgtta atgcagaaag gccggcatta
    14341 acggcaatac cggacaataa gattcgattc atacccaaaa agccatttcg atcataggcc
    14401 gcaagataga cacagcaagc agctaaaaca ccacctagaa aggctacaac tagcaataga
    14461 aacggcagcg aatagtgcga aaagaaacct aaataaagca tcactaaaaa tcctgctccg
    14521 gcattaatgc ccaatatact agaatctgcc aattcatttc ttgttactcc ttgcaagata
    14581 taaccagaaa cgccaagaca agctcctgct aataaactga tcagtaatcg aggaactcga
    14641 aattctctaa caatcagcgc caaagaagat gattctttcc ctatgaacgt ggcaaaaagc
    14701 tgatccaggt aaataaaagg cgtaccaatc attaaactac ctatagacag gatgacaagt
    14761 acaaaaagca agaaatagaa cgtccaatat atttttttca ccgttgttcc ctccttactt
    14821 gtatcagtaa aaacggaacg ccaatcaatg caatgactaa tccaaaaggt gtttcaaaag
    14881 ggggattgat catcctcgct gtaaaatccg ccaacataac caatccaccg ccaactaaaa
    14941 aagagacagg tagaacataa cgatagtccg ttccaaccat tccgcgaaca actggcggaa
    15001 ccaacagccc aataaatgaa acaggtccga ctaacgaaac ggcaatggct gctaacactg
    15061 caactagaca gaaaacaatc aaccgcgttc gtttaggatg acttccaaga gctaatgcat
    15121 gtgtttcact caaatgaatc aaagatattg cttttcctaa tgaaaaagaa accaaaacag
    15181 caagtatata taaaggaaac aatactgcta attgtttcca tgtgatattg gcagctccgc
    15241 ctacaaacca aaaagcaaga tcctgctgca gattaaagaa ttgggtaagt gcttggctga
    15301 tagcagtaaa aaaagaacta atagctacgc cagctaaaat cagctgtaaa ggattcatgc
    15361 ccattttcga aaactgcaaa aaaccaaata cgagcaaagt tacagcaaaa gaacctgcca
    15421 atgacattag aaacacagaa aaatcagaag ctttaggcca aaaagcaaaa ctaagggcca
    15481 ttgccaacga agcacccgcg ttgattccta gtaagcctga atctgctaaa ggatttcttg
    15541 tcactccttg catcaatgca ccgctcaatg caaaacaact ccctacaaga aatgctcccg
    15601 ccacacgagg caaacgaata tttcgtatga tttggtgact ttgttttgat ctatcaaaat
    15661 caaacaacgc ctgccaaaaa tctgcttttt ccacagtcgc tgcgccattt gaaagagcaa
    15721 caaaaaaaat aatcaaaaga acaaaacaga ccaaaagcag gagtctattt ttcttcatag
    15781 tcctcataat tgatcctcct gctcttttgg caacaaatca taggttagaa aaactggttt
    15841 atttgttctt ggaagcgtga caatcgttgc atcaatctca aatatttttt tcatacactc
    15901 ttttgtgatc acttcttcag gtgtaccttc tgtgatcaac ttaccgtttt tcattgctaa
    15961 taaataatct gaaaaacgtg aagcatgatt aatgtcatga atcgacatca agatcgttgt
    16021 ttgtttcatt tgattgattt cagtcaataa ctgtaggatc tctaattggt gtgccggatc
    16081 taaaaatgtt gtcggttcat ccaagatcaa gatatctgtt tcctgagcaa gcgccatagc
    16141 gatccagaca cgctgggttt gtccaccaga cagcgttgcg atatcccgca tacgaaatcc
    16201 agctagacct gtagcatcca acgcccactc aattgcttca tgatcttgcg tgtccatgcc
    16261 actgaacagt ttttgataag ggtatcgtcc gtaagatact acttcttcta ctgtcatacc
    16321 tgtagggtgt tcactagttt gtgctaataa tgcaattttt tttgcaagtt cttttgaact
    16381 gtatgtagag atatcagagt tattgacaat gatctttcct gatttcacag gtagtatacg
    16441 ggtaaaactt ttcaataaag tagattttcc acttccattt ggcccaatca aactagtgat
    16501 tttcccttca ggaatcgtaa cagacatgtt ttcaatgatt tttttgtttt cgtagccggc
    16561 tgcaatgtca gctgctctta atctcgtcat ttcacccatc ctttcgctga aaatcattct
    16621 caattatgac gctgtttcaa catttcgtca agcgctactt tcatatctat agccaaatga
    16681 agcggttgac agcgttcgaa atatcaggaa taataaccaa tgagaaagat tctcaattat
    16741 gttaggagga aagaaatgaa attaaaaaca aaagtattca cattatctag catattgctg
    16801 ctggctggag tactgagcgc ttgctccccc tcttcagata aagaaacagc tacaactgcc
    16861 aattcgacga cttcatccaa tagtactcat acagtcacag atacacttgg acataaagta
    16921 gagattccaa acgcgcccaa acggatcatc ggcagttact tagaagacta tctgattgca
    16981 ctaggggaaa aacctatcgc ccagtggact gttggcagtg gttccattca agattatctg
    17041 caagatgatt taaaggatgt cccaacgatt tcttatgacc ttccttatga gaaagtgtta
    17101 agctttgagc ctgatttgct gttgatttct tcttccgcta ctgtcgaagg cgggaaatac
    17161 gaacaatata gcaaaatcgc gccaacttat gttgtaaaaa acggaacaga tgtcacatgg
    17221 gaagaacaac taaaagatgt cggcaaagct ttggcaaaag aaaaagaggc agaaaaaatc
    17281 atttccgatt atcaaaaatc catcaagaaa actcgagaag aactagcaga taaaatcgag
    17341 aacaagacag ctgcagtgtt gtgggtgacc aacaactcag cctttatggt cagcaaaaat
    17401 cggtcaagtg gaagaatcgt atacgacgat ctggaatttg gtgttcctga tctagtggaa
    17461 gaggtctcca aaaaagccac ttctgactgg tctgctgttt cctctgaaaa gctagctgaa
    17521 ttagatgctg actacatcat ccttgtgaac agtgacaaag atgctgccat gttcaatgaa
    17581 ccaagctgga agaatctaaa agcagtgaca gacaatcatg tactgcaatt cggacctgaa
    17641 tctagttggc tatataacgg acctattgcc agtcaggaaa tggtcaatga tatcaaagaa
    17701 aaactaaatt gattttaact aaaaaaagca tcttcacgat tagtcgtgag atgctttttt
    17761 tcttattaac aaactagacg catagatttt attcttcttt tgaagcaacc ctatttttta
    17821 ctctttccca tttttgaaaa cgatgggcat atagattttc ttgatccgtt atcccctcat
    17881 actcctctat aagggcgaag tctgaaaaat caatattccc aatatacgta tcgccttcaa
    17941 acgtgctatc gatcaatgtt cgccagatcc gaccagtgta aggaagaagt tcttgaaaaa
    18001 tccgactacc acccgaaaca tagatatctt ctgagatcgt ttgactatac gacaaaagtt
    18061 catcgatcga atgcattact tccgcatttt ctttcgtgcg aaaatttggt tgcgttgtca
    18121 acacgatgat atggcgataa ggaagtgaaa gatcccccat tccttcatag gtctttcttc
    18181 ccatcactaa aattcgatcc attgtatgtt cgcgaaagaa acgcatatca tttggcaatc
    18241 gccatggtaa caaaccattt ttgccgatca gaccattttt atcttgtgcc cacatggaaa
    18301 taaacatatt atccgctcct tatgatttta gatgttttga gataaaaaaa gtctcaattc
    18361 tttgaccagc aaggaattga gaactttaaa aacattattt tgtttcacgg tgcaaagtaa
    18421 ctttgcgttc gcgtgggcaa tatttttgtt tttccaaacg atcaggattg ttacgtttgt
    18481 ttttgcttgt tagatagtta cgttctttac aagaagtaca ctctaaagtg atgtttacgc
    18541 gcatgttttt ccctcccatt tttacaagaa tcctctaaga tgactctcag acttgattat
    18601 cttaccatga ttttttctag attgctagtg tttttcacga ttttgttaag taaaactact
    18661 tgacgataaa tacaacggtt ttacttctca aacaaaatct ttttcttttt gtataaatac
    18721 ccttacactt gtttatatag attatgtttt ttaataaagg gggatactaa tatgccatgg
    18781 aacatgaagg actttcctgc atcaatgaaa aacttagata aattgacaag aaaaaaagca
    18841 atcgacatcg caaatgcatt attagatgaa gggtaccctg ataaccgtgc gatcccaatt
    18901 gccattgatc aagcaaaaaa atggtatgaa gatgctagtg aatcagaaaa acgaactttc
    18961 gaaaaagaaa aaaatccaag caagacggat gaacacgata cgaatcctcg tgctggaaaa
    19021 ctgcttgatt cagatgtgat cgtagaatat gaggaagaac aatggatcgt gaaatctaaa
    19081 ggggcaaaaa aggcaagcaa ccattttgat acaaaaaaag aagcaatcga aaaaggaaag
    19141 caagtagcac aaaacaaaga atcaactttg ttcatttata aaaaagatgg gacaaaagaa
    19201 aaagaaatcg attattgaac atatgtaaag gggttgtgac gaaaatcgtg tcacaacccc
    19261 cttatgttcg aaacaatggt gttcctctgc caactccgaa ccataagtca taatatctat
    19321 aaaacgggaa gagctgtttt ttgaaattgt ttcttatcac tcagtgttaa acggtaggag
    19381 aaaacctctt ttttattgat atttgatttt catcaaacag tcacatagtc gattgcttct
    19441 gcttgcggaa tcgtttcatc tacaaagtag actttatacc atgtcaagaa actgaagatt
    19501 gtccagattt ttctttgctc ttctttacgt ccttcgtgat ggtcatctag caacttcatg
    19561 attttttctt gatcaaaaaa ttcttttgca aaatctgctt cgaataatgc tttgacttgt
    19621 tcgtagccgt gttcttcttt caaccaagct ttgattggca cagggaatcc taatttcaca
    19681 cgattcgacc attcttccgg aagatgtttg ttcgcagctt gtctgaaaat atcttttgtg
    19741 ttgttttgat tcaataaaaa cttacttggt atttgttgag ccaatttcat gacttcgata
    19801 tccaataaag gtactcggac ttccaaagaa cttgccatag aaagtttatc tgcctttaac
    19861 aagatatctt ttggcatcca ttgatgaaga tcgacatatt gcatcttatt gacttcatct
    19921 ttgattcctt ctgttttctc gtaatgaaca gtcatgattt catccacaga tggtgctgtt
    19981 tgatattttg gtgttaacac ttctgatgct tctgattctt cgaacactcg agcatgaccg
    20041 ataaaatatt cttttgcagg agcaagtgat tcatataaat ggatccgtcc atggaagttt
    20101 ttcatttttc cgattttacg tcctaaatta tagcgtgttc cttttggtaa ttttttcaat
    20161 ccttgagcaa tcacacggat gaattttgaa ttcgtatgga atccatacgt ttggtatccc
    20221 gcaaacagtt catccgcccc ttctccagat tggactaccc gcacactttg tgaagcaaga
    20281 tttgctaaaa agtacaaagg tacgcaagaa ggatttgaat caggttcatc taagtgatac
    20341 tggatcaaag ggaatgcttt gaacgacatg tctccgtcga tcactgctgc tgtattatct
    20401 aagtccaata gttcggttag ttttctggct tcaatcgctt cattataggt tttatcatca
    20461 aacccgattg agaaagaatg atctggtttc aatacagagg ttacataact ggaatcaacc
    20521 ccgctggata agaaagaacc aacttctaca tcactgaccg tatgtgcttc aatagaagct
    20581 tgaacggttt cgtcgatttt ttcgatccat tcttgtcggg aatgcgtttc ttttgtttca
    20641 aaatctgcat cccaatattg ctgaatgtct atttttccat ctttatacgt ataataatgg
    20701 ccttcaggca aacgatagac atctttgaag aatgtttcgc cgtttaatgg agaatattgg
    20761 aaagtcatat aaggtttcaa cgcttctttg ttcaattctt tgttaaaatc aggatgaggc
    20821 agaaaacttt tgatttctga accaaacata aatgttccgt tcatttctgc ataataatat
    20881 ggtttgatcc caaagtggtc tcttgcaccg aataactcat tcttttcatt atcccaaata
    20941 gcaaaagcaa acattccgcg gatcttttgc aataattctg ttccccattc ttcgtaacca
    21001 tgcaaaagga cttctgtatc tgcatgtgtt tgaaaaacgt ggccagctgc aatcaattct
    21061 tctctcaaag gctggtaatt atagatttcg ccattaaaaa taatgatctt tgtccgatct
    21121 tcattgtaaa taggctgagt accgccctct aagtcaataa tacttaatct tctgaatcct
    21181 aaagcaacat gtttatcgat atattctcct gaactattag gtccacggtg aacgattcga
    21241 tccatcattg tattaataat tgtttttttg ttgtccttgt cgttaacaaa acctacaata
    21301 ccgcacattt aactttcaca tcctaatata aaattactgt ttatttcatt catatgcatc
    21361 ttatcataga ataaatagcg gacgaatatt ttctctctta caatttcgtc acgtgaaaac
    21421 aaaagatgaa agtttctgtt tttacagaaa ataaagtccc aatatctaat ttaccatgtt
    21481 ttcttttttg aggctacctt attctcttcg tgttaaaaaa atattagtgg atgctatttc
    21541 caaaaaaacc agcaaaaaaa gacacgacct aaagatcgtg tc
//
LOCUS       DAIGWC010000048        21120 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.049, whole genome shotgun sequence.
ACCESSION   DAIGWC010000048 DAIGWC010000000
VERSION     DAIGWC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21120
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.049"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(52..1155)
                     /locus_tag="NOB74_001827"
     CDS             complement(52..1155)
                     /locus_tag="NOB74_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI1221015.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            1707..2255
                     /gene="aac(6')"
                     /locus_tag="NOB74_001828"
     CDS             1707..2255
                     /gene="aac(6')"
                     /locus_tag="NOB74_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCI1221016.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            2801..4462
                     /locus_tag="NOB74_001829"
     CDS             2801..4462
                     /locus_tag="NOB74_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1221017.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(4532..4879)
                     /locus_tag="NOB74_001830"
     CDS             complement(4532..4879)
                     /locus_tag="NOB74_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HCI1221018.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            4963..5904
                     /locus_tag="NOB74_001831"
     CDS             4963..5904
                     /locus_tag="NOB74_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1221019.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            5905..6948
                     /locus_tag="NOB74_001832"
     CDS             5905..6948
                     /locus_tag="NOB74_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1221020.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            6954..8024
                     /locus_tag="NOB74_001833"
     CDS             6954..8024
                     /locus_tag="NOB74_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221021.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            8014..8967
                     /locus_tag="NOB74_001834"
     CDS             8014..8967
                     /locus_tag="NOB74_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1221022.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            8979..9989
                     /locus_tag="NOB74_001835"
     CDS             8979..9989
                     /locus_tag="NOB74_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1221023.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(10274..11095)
                     /locus_tag="NOB74_001836"
     CDS             complement(10274..11095)
                     /locus_tag="NOB74_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI1221024.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(11192..11470)
                     /locus_tag="NOB74_001837"
     CDS             complement(11192..11470)
                     /locus_tag="NOB74_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221025.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            11738..13747
                     /gene="metG"
                     /locus_tag="NOB74_001838"
     CDS             11738..13747
                     /gene="metG"
                     /locus_tag="NOB74_001838"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HCI1221026.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(14226..14813)
                     /locus_tag="NOB74_001839"
     CDS             complement(14226..14813)
                     /locus_tag="NOB74_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221027.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            14988..16310
                     /locus_tag="NOB74_001840"
     CDS             14988..16310
                     /locus_tag="NOB74_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1221028.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            16465..17241
                     /locus_tag="NOB74_001841"
     CDS             16465..17241
                     /locus_tag="NOB74_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCI1221029.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            17234..17803
                     /gene="rnmV"
                     /locus_tag="NOB74_001842"
     CDS             17234..17803
                     /gene="rnmV"
                     /locus_tag="NOB74_001842"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HCI1221030.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            17796..18680
                     /gene="rsmA"
                     /locus_tag="NOB74_001843"
     CDS             17796..18680
                     /gene="rsmA"
                     /locus_tag="NOB74_001843"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HCI1221031.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            19131..19760
                     /locus_tag="NOB74_001844"
     CDS             19131..19760
                     /locus_tag="NOB74_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221032.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(19884..20993)
                     /gene="ugpC"
                     /locus_tag="NOB74_001845"
     CDS             complement(19884..20993)
                     /gene="ugpC"
                     /locus_tag="NOB74_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HCI1221033.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
BASE COUNT         6871 a         3785 c         4275 g         6189 t
ORIGIN      
        1 aaatgtcctc aatttgatga cagcctgctt gatgggggtt ttagcaatta tttaactgat
       61 tttcttatat ccttgctggc tttcttgtgt agcatgataa gtttctacgt caagaatggc
      121 ctgtttaaat ttttctcggg tgatttcata aggcacatgt ttaatatcat ttgttgccat
      181 ggctttatct aagattgctt ctaaatcggt cgtgacattg agattcatgt cggttaacga
      241 tactggaagt tggttctttt tcataaacac atagatttta tcaaacaaat cgaactgctg
      301 atccatcatc aataaggtca gtacaccata actgacagat gctccgtgaa ggtatccctc
      361 cattttttct agaacagtcg taccgtaata gaatgagtgt gccatagcag aattatagtt
      421 attgttaact aaaacagaaa ccaatccggt agtaacaatg atatccgaaa cgacttgttc
      481 aattgcatat gagggacgat cgtcggcact atctttcaat gcttgcgtac cataagtcaa
      541 gagacgatca atgcacattt ttccgatttg gattcctaat ctatccgtgt agcctagatc
      601 atcgccacga gcagaaaaag tagattcgac ttctttggat aaagcatcgc caatacctgc
      661 ccataagtat ttatcaggtg cttcggcaat aattgctgta tcaatgaagg tgtgtacagg
      721 tggttttgaa ggaaagaaga gtccgtccat tacgccttct tcgttataga tgacacatac
      781 cgcagtgacg ggcgaacagt tcgaaccaat agtgggaaag gtgaagactg gtttagctag
      841 tttttcacca atgactttta cagtatcgca agcacggcca ccaccgactg caaacaggac
      901 gtctgctttt tggacacttt catgctggat caactgttca atatttccat aagttgaatt
      961 acccccgtac cagagactgg cgacaacctc tatttcctgt gtcaaagcta cttttatttt
     1021 gttttctgcc tttgaaagtg cagtcttccc tccaatcagc actacttttg tcccatattc
     1081 tttgacgatt ccatttgctt tttcatacgc atctgttcca atggtataat ttggtaagaa
     1141 aacactttga ctcatattca tttccttctt tcttcgttga aacgggttaa aattttaaag
     1201 agtgatcgat ctgactgcgg ctgtagatgg agtagaggtg aacctaagac aggataagtg
     1261 atgaataagg tggcatgaac accttgaaat catcaataag tatcctaaaa acgaacaagt
     1321 acaaaaacat tgaaaacgac aataatgaat ttttgttcct cttagtattt ctaccgattc
     1381 cctttgcttt tttgtaatta tctaaaaatt ctaaaaatta agattattat atgaaaacag
     1441 gttttatttg tcaattcata attggttttt tttaaagcaa aagataatct atatcatgat
     1501 gaacaaacag agttttttcc tccaattgat ggctttcctg atctttccta ttttgaataa
     1561 agtgtttctg tataattttt tattttataa gtaagataaa taatgaaaga atagagatac
     1621 tgattggtag ctaaagattt ttgagcgaga acatttcgtt ttttcaaaag gactgttaga
     1681 ataagcaaga acaaggggga agacgtatga taatcagtga atttgaccgt aataatccag
     1741 tattgaaaga tcagctttct gatttactga gactgacttg gccggaagaa tatggagaca
     1801 gctcggcaga agaagtagaa gaaatgatga atccagaacg aatcgcggta gcagcggtag
     1861 accaagatga gttagtagga tttattggtg caatccctca atacggtatc acaggttggg
     1921 aattgcatcc attagttgta gaaagctccc gacgaaagaa ccaaataggt actcgattag
     1981 tcaattactt agaaaaagaa gtagcttcca gaggaggaat cacgatttat ttaggtacgg
     2041 atgatttaga ccatggaaca acgttaagtc aaacggacct gtatgagcat acatttgata
     2101 aagtggcttc catccagaac cttcgtgaac atccgtatga attctatgaa aaattaggtt
     2161 ataaaatcgt aggtgtctta ccaaatgcaa atggctggga caaaccggat atttggatgg
     2221 caaaaacgat tattcctcga ccaaattctc aataataaaa agaggttgtg acagaagtaa
     2281 tcagcttcaa gaaataagaa ggaatttacg aaaattactt cttgaatttt tgtgaaattc
     2341 caacttattt ccgaagaagc tacttttgga acaccgtgta ccagaggttg tgaaaaagtc
     2401 gcttagtttc gagtagtaag aaaaattttg tgaaaatggc tttctacatt tttgcataaa
     2461 tttggcttaa taccgagaaa ctggcttttg aacaccgttt attcagataa gggactgtga
     2521 caagactttt gtcacagttt ctttttgttt attctttttt atctttgtat ggcaataata
     2581 gacaatataa cgaaaattat ttaatggctt ttggaagacc atggaaaacc ttgtacaaag
     2641 ctattttttc tgaaaaattc cttgaaacct cacgaaaaaa tcattatttt atgaaaaaga
     2701 caaaaaaaag tgttgatttt ttaataatta ttcattaaac tcttaaacaa cttcagaaaa
     2761 tattaattat tctgaaaatt ccaataaagg ggtacgtaaa atgaaaaaga aatttacatt
     2821 tggtttggtt gcggtatgcg gccttgtact tgctggatgt tatggcggca gttcagccac
     2881 aagcagtagt tcagcaaaaa gcggttcagc agatggagga ggcgtattta acttagtcgt
     2941 gcctcaagaa atgcctacag ctgacttatc agttgcaaca gatacaatca gttttacagc
     3001 attgaataac gtttatgaag gaatttaccg tcttgatgaa gacagcaaac cacagccggc
     3061 aggagctagc gagttggcag aagtcagtga agacggatta acttacaaaa tcaaattacg
     3121 agaagacgca aaatggtcaa atggtgatcc tgttacagca gcggattacg tttatggctg
     3181 gcaacgaaca gtagacccag ctacagcttc tgaatatgct tacctgtatg cgccagttga
     3241 aaatgcagaa gacattacag ctggaaagaa agataaatca gaactaggga tcaaagcagt
     3301 tggtgactat gaattagaaa tcaaattgac gaaacaaaca ccatatttcc aatatctgct
     3361 tgctttccca tcatttttcc cacaaaaaca atccgtagtg gaagaaaatg gggatgccta
     3421 tgcatctgca agtgataaag ctgtttataa tggaccattc acattagaag attttgatgg
     3481 accaggaaca gatacagaat ggacttataa gaaaaatgat cattactggg acaaagatac
     3541 agtaaaactt tctgaaatca aagtcagtgt agtaaaagaa tcttctactg cattgaactt
     3601 attcaaagat ggccaagcag atgacgtgat cttgtctggt gagttagcac agcaaaacgc
     3661 aaacgatcca gcttatactt ctgttaaaga agcgcggaca agctatatcg aattcaatca
     3721 acgtgaaaag aattcaccat tcaacaatgt gaacctaaga aaagctattt cttattctat
     3781 cgatcgtgaa gctttagtaa aacaagtact aggtgacgga tcagttgtct ctacaggatt
     3841 gatcccatca gatatggtaa aaagtccaac aacgaacgaa gactttgcaa aagaagctgg
     3901 aaaattagtt tcttatgaca aagataaagc aaaagaatat tgggaaaaag cgaaaaaaga
     3961 attgggcgtt gattctttag aatttgattt gatggcttct gatgatgatt catcgaaaaa
     4021 agtaatcgaa tatgttcaaa actcaatcca agaaaacttg gatggcgtaa cagtcaaacc
     4081 aacacctgtt ccattctctg tacgtcttga ccgctcaact tcgggtgatt ttgacgcagt
     4141 actaggcgga tgggctgctg actatgcaga cccaagcagc tttactgatt tgtttgtcac
     4201 aggtaattca tacaaccgtg gtcgctggag caatgcagaa tatgacgaag cagttaaagc
     4261 agcttcatca acagacgctg gcgatgaaca agcccgttgg gatgatttcc aaaaagcaat
     4321 caagatcatc tctgatgata tgggtgtcgt tccggtgtac caaaaagcag aaggtcacct
     4381 agtgaatgaa aaaatcaaag gtatcgttca ccatgcggca ggcgcttcat gggattacaa
     4441 atggacatac gttgaagaat aatcgttaat accgtgagca tgagaaaaaa cgaggctgcg
     4501 gcaaatgtcg caacctcgtt ctcatattca cttatcctaa caaagaaaaa agcatgaaaa
     4561 tagcagaaag agcaattagt attccggcaa tgatcagcca aaagctgtac ataccgtagc
     4621 tggcagacga gagcgtggaa aattctggtt ttttctttcg gttccttgtt cgtgcaagat
     4681 ggaccgatcg ctgaaaatga tcgaagaaac ccgaagaaaa gacccataaa aaaccgccga
     4741 taatcagaaa cggcaatgac cataagaata gatcattaga taattgaatg agtgtaaagg
     4801 aatggttgat gagatttttt attaaaataa ccagaatcag tagaaaagct actgcgtagg
     4861 ggatagattt ttttttcatt tgattgctcc tttatttttg gttcattatc taataatgta
     4921 gcgaaacatc tgtcagaagt caaaagctag ggggaaacat tagtgaatag ttatatcaaa
     4981 tatgtattaa aacgtgtctt tttcatgatc atcacgcttt ggttaattgc aacaatcacc
     5041 tttttcttga tgcaattgct gccgggcacg ccatatacga atcaggaacg tttgagtcct
     5101 gaaacaatcg agatgctaaa taaacaagtc ggtttggata aaccagttat cgtacaatat
     5161 gggatttatc tttctaattt gcttcaagga gattttggaa tttccttcca atttaaaaac
     5221 cagccagtcg cacatttgtt agctggaaga atcggaccat ccttgcagtt agggttacag
     5281 gcaattatct ttggaacagt cctagggacg attttaggaa cgatctctgc catgaagcaa
     5341 aatacatggg cagatacatc ttctacactc gtagcgatat taggtcgttc cattccaaac
     5401 tttgtatttg ctgttttatt acaatatatc tttgcaatca aattacaagt tttgccaatc
     5461 gcaaaatggg atggctttgt gtacacaatc ttaccaacaa ttgcgttggc catgtcgccg
     5521 cttgctgact ctgctcggtt tatccgtacg gaaatggtgg aagtactgca tagtgattat
     5581 gtggaattag caaaagcaaa aggattgagc cgttgggaaa tcgcctttaa acatggtctt
     5641 cgaaatagtt tgattccatt gatgacttta ttaggaccgt tagctgtagc attgatgacc
     5701 ggatcactgg tggtagaaaa tatctttgct attcctggta tcggggaaca attcgttaag
     5761 tcaatcacaa caaatgatta tcctacgatc atggctgtaa cgatccttta ctcatttatg
     5821 ctgatttttg ttattttgat cgtggatcta ttgtacggtc tagttgatcc aagaattcgt
     5881 gtttcagaag ggagccgagg ataaatggaa atgataccaa agcgttatga aacagttgca
     5941 gatatccctg cggatgaatt tcttccatta caaaaaaata ccgaagaaga acgtgaacag
     6001 attactgcac cttctttgaa ttttatccaa gattcatggc gccgtttaaa gaaaaacaaa
     6061 gctgccgtta tttcaatggt tttactattg gtcatcattt tgatctctgt gatcacaatc
     6121 tttgtttctc ctcatgatcc aactgcccaa aacgtggctt atatcaattt gcctcctcgt
     6181 attccgggaa tcaatatcga tggattgaat ggaaaagcaa tggttggtgg tgaacttgtt
     6241 gataaatatg ctcaagcaaa cgtcccttca aacgtaaatt tctttttagg aacagacggt
     6301 ttgggacgtg atgtattaag ccgcttattt atgggaatga gaatctcgtt gctgatcgca
     6361 tttattgctg cattactaga tgtaacgatt ggtgtagctt acgggttggt ttctggtttg
     6421 ttaggcggac gtgtcgataa cgtgatgcaa cgttttttgg aaatcttatc aggaattcca
     6481 aacctcgttg tcatgatttt gatgttggtc gtttttgaac caggaatttt ttcaatcgtg
     6541 gctgctatgg ccatcacaaa ctggatacca atggcacgta tcgttcgtgc acaaacaatg
     6601 aaattaaaag atcaagaata tgttttagct ggattgacat taggtgaatc aagaatgaaa
     6661 attgcattca aacatatttt gccgaatatc tctagtgtca ttattattca aatgatgttt
     6721 agtattccat ctgctatttt cttcgaagcc tttttaagct ttatcggttt aggtcttacg
     6781 cctccgtcag cttcattagg aacgatgttg agcgaagggt acaagacatt cctgtatctg
     6841 ccttatctat tatggattcc ggcagtaact ttatcggtta tcatgattgg ctttaactta
     6901 cttgctgatg gattgcgtga tgcctttgat cctaaaatga aagagtgaag acgatgacga
     6961 aaattttaga agtgaaagac ttagaaatct cttttgatac gtatgctgga aaggtacgag
     7021 cgattcgcgg tgtcaatttt catttgaata aaggagaaac attggcgatc gttggggaat
     7081 ctggaagtgg aaaatcagtg acgaccagaa gcatcatgcg cttgctgtca agcaacgcca
     7141 atatagatgc tggtcaaatc ctctttaaag gtaacgatat cgttggaaaa tcagaaagag
     7201 agatgcaaaa aatccgtggt aaagaaatag cgatgatttt ccaagatcca atgacctctt
     7261 tagatccgac gatgcccatt gggaagcaag tcgctgagtc ccttagaaag cataataaag
     7321 tttcaaaaaa agagggacaa aaagctgcat tagaattgct taaattagtt ggaatacccg
     7381 aagctgagaa acgtatcaac agttatccgc atcagttctc aggaggtcag cgtcaacgga
     7441 tcgtgatcgc gattgcactg gtatgttatc cggaaatcct gattgctgat gaacctacaa
     7501 cagcgcttga tgtgactatt caagcacaga ttttggagct gctgaaagaa attcagacaa
     7561 aaatcgatac atcaattatc tttatcactc atgaccttgg tgtagtagcg aatgtcgctg
     7621 atcgtgtcgc tgtcatgtat ggaggaagaa tcgttgaagt tggaacatcg gaagaaattt
     7681 tctacaaccc gcaacatccc tatacttggg gactgcttgg ttcaatgccg acattagata
     7741 gtgcgaacga tcgattgtat gctattcctg gttctccacc ggatttattg aacccgccaa
     7801 aaggagacgc attctatcca agaaatgaat tcgcgatgaa aatcgatgca gaacaagaac
     7861 caccattttt tgaactatca aaaacacaca aggcagcaac ttggctactt gctccgcagg
     7921 cacccaaagt gacaccgcca gaagaaatcc aacgtcgctg ggctatcttt aaagagaaac
     7981 aaaaacatac ttacggtcaa ggaggaattg ctgatgccaa ataaactact tgaagttaaa
     8041 ggattgaaac agtatttcaa tgtaggaaaa aagaatgaag tacatgctgt aaatgacatc
     8101 agctttcaca tttatgaagg agaaacattc ggtttagttg gagaatctgg aagcggaaaa
     8161 tccactactg gccgtacgat cattcgcttg aatgaaccta ctgatggtga gatattattc
     8221 gacggtcaag atataacgaa gatcaaagat aaaaaaggtt tgacgaaatt ccggcatgat
     8281 gttcagatga tctttcaaga tccatacgct tcgttgaatc ctcgtatgaa agtcagagat
     8341 atcattgccg aaggaattga tgttaatgga ctagctaaat catctgaaga gcgtgcaaaa
     8401 aaagtcgatg atctattgag aactgttgga ttgaatccaa gccacggtac tcgttatcct
     8461 catgaatttt caggtgggca acgccagcgt attggtattg cacgagcatt ggcagtaaaa
     8521 ccgcgtttta tcatttgtga tgaaccaatt tctgcactag atgtgtcgat ccaagcccaa
     8581 gtggtcaatt tgttgcaaga tctccaaaaa gaacatcaat tgacctatct atttattgca
     8641 catgatttgt cgatggttaa acatattagt gaccgaatcg gtgtaatgca taacggcttg
     8701 ttattagaga tgggaacaag tgatgaaatc tataatcacg gtgttcatcc ttatacagaa
     8761 agtttgttat ctgctattcc tctaccagat ccagaccatg agagaaaacg cagaagaatc
     8821 aaatatcaac ctgaaccaga tgacggacaa gtacgtcaac ttcgtgaaat cgcaccagaa
     8881 cattttgtct atgcaactga gcaggaagtc ccatattacg caaaaaaact aaaacgacaa
     8941 aaggaatctc ttctggttgc taactaggag ggacatagat gctaaaagct tttaaattcc
     9001 gtatgtatcc gacagaagaa caaaaacagc aattgattcg tacttttgga tgtgctcgat
     9061 ttacctataa ccatttgctg aaaaagcggc agaaaagttg gcaacaaaca ggagtagcca
     9121 atttttcgct cacacccgct acattaaaaa aagaataccc attcttaaaa gaagtagaca
     9181 gtcttgcttt agcaaatgca cagcttaatt tggatcgggc ttttcgcaat tatttcaagg
     9241 gacgtgccag cttcccaaag cttaaaacga aaaaaagtat gtggcaatct tatacgacca
     9301 acaaccaaac ccgtacgatc tatctggaaa atggctactt aaagttacca aaacaaaaag
     9361 aactaatcaa gataaatcag catcggccag ttgaaggatc gattcgctcc gctacgattt
     9421 ctgctcgata taatgaagaa ttttatgtcg cactactttg tgatgtttcg ccagtaaaaa
     9481 aagaatcttt agctaaatgg atcgggatcg cctatcatcc gaagacattg atccaaacat
     9541 ctcgacctct agaagtaact ttaccaaaat ttcaccagac agaagaaaag ctgcaacatg
     9601 cacagcggaa attgaatgtg aaagtccgct ccgctcacca tagaaagatc aggttagatc
     9661 aggcaagcaa ttatcagaaa caaaagagaa aagtaatgga tctttatctg aaacaaaaga
     9721 accagcgaga agattatctt gaacaattat ctgggaaatt ggtcaaacaa tatgactact
     9781 tatttgtaga atcttttcca aaagaagagg cacatgctga tttttctatt cacgactggc
     9841 ataaattaat aacaaaattg cgttataagt cccaatggta taataaaaaa tttcttttga
     9901 tcaataccga cggagcagaa gaaagcaatt ccgtaagaaa gagccaagta gtagaaaaaa
     9961 tgggcagaca ttcggttatc aagggataaa aaatgaatga aactgatagg agcgttaggg
    10021 ttagccttgt taataaaaag tcttaatgac ttttgtttct aggaattttt cttttgaaga
    10081 aaagctcact aattatgaca aaccaataaa acaatagcag aaaaagttcg tacgagcttt
    10141 ttctgctatt gttaattttt tattcagaaa gtttacgaat acatcaaaat tctgaaacaa
    10201 aaaacgtaac tcacaaagag ttgtttttgc gttttttctt gaatgattag gtctgaatct
    10261 tttgctcaca accttattca tggtgccccg gcttgagctg atagattttt gaaggacggc
    10321 cgattcctac aggacgttca ccgatctcat cgaaatattg gagcatagct ttcttaaaat
    10381 tggaatgatc gatcgtttta taatcgatcc ctaagaattt agcaaatact tttcgagctt
    10441 ccgtaatcgt gaaatcttta cctaaaactt gtagaacttg cggctcgtgt tccattttat
    10501 tgactacacg gttgaatgct ttcaagatga tttgactatg gtcaaaagcc aaagtatctt
    10561 tgccagaaga ctctccagtg actaaatcaa gcgagatagc cacttctccg ctagataaat
    10621 ggatcttgtt actatgacgt tctagtgtga accagcgtac ttccttggca tcatctccgg
    10681 cgattagcgg ttcttctcca ataaaggcta agtagctgac tgtgacgacc cagcctcgcg
    10741 gatctcgatt aggcgtactg aatgtatgca gttgctcaat attttctttt gaaataacca
    10801 caccagtttc ttcctttgtt tctcttaaga cgctttctcc agttgactca tccttttgga
    10861 caaagccacc aggcaatgcc catgaatttc gataaggatg cccttttctt tggatcaaca
    10921 aaactttcag ctgatcttct tctttgttat agcacatcag tacgatatcg acagtcaaag
    10981 agggcttgtc atattctgga cgttcctgtt tttgatacca gttaagaaat tcttcttcac
    11041 ttgctttatg ttcataatat aatttttctt cttctttaga agcaaaacgg ttcatctgac
    11101 cacctccatt gacagtaaaa gtacttttta ccttattgta gcagactctg aaaaaaaacc
    11161 aaggatttac ttgaaaaatc taggttatca tttaaatatg aaaaataaat ggaagtatga
    11221 gattgaataa aaagaaaagc agataaaacg gcaatacttt ataccgctct tcacgaatgg
    11281 caaagaagcc acaaataacg atatatacgt caatgataaa acgcaaaatc caagctgctg
    11341 tcataaaact gttcaaatgc ccatggaggt taaaataacc atacatacga atataaaaat
    11401 agctgaatat taaatgtgct aatgaaagaa aagcaatact aagtgtaaaa aaaagatgtt
    11461 tcttctgcat gattgttcca gtcccttact aagatagata gtctttatta taccacgtgt
    11521 gaggggagaa ataaaaagcc gttttttagt agatatgaaa caaaacaaaa acccgcattt
    11581 attcaaccta ttcatccttt taaaggatag attgaacgta gatagaagtc gtttatccag
    11641 tctttttcat tttgaaaaaa agctaacagc atgctttttt tatggtatac tagcaaggaa
    11701 acgaattcgc atcatgcgat aaaggaggaa gagccccgtg gcagaaaagg aaacttttta
    11761 tatcactacg ccaatctatt atccaagcgg caaacttcat atcggcaact cgtatactac
    11821 gattgcatgt gacgcaattg ctcgttataa acggttgatg ggctttgatg tgttttatct
    11881 cactggagtg gatgaacatg gtcaaaaaat cgaaacaaaa gcagaagaac taggtgtaaa
    11941 accgcaagaa tatgtagata aaatggcggc tgatgtcaag aaattatgga aaacgcttga
    12001 tatcagttat gataaattca ttcgcacgac agatgattac cataaagcag ctgttcaaaa
    12061 aatatttgat cgtttattag aacagggaga tatttactta ggtgaatatg aaggctggta
    12121 ctctgtttct gacgaagaat tctttacaga aacacaactt gcagaagtgt acaaagatga
    12181 cgaaggtaac gtgatcggtg gtaaagcgcc aagtggacac gaagtagaat tggtaaaaga
    12241 agaatcatac ttcttccgca tgagcaaata cgcagaccgt ctattggaat actatgaaga
    12301 acatcccgaa ttcatccagc cagaatctcg taaaaacgaa atgatcaaca actttatcaa
    12361 accaggatta gaggatcttg cagtttcacg aacaactttt acttggggag taccagtcaa
    12421 gagtgatccg aaacatgtgg tgtatgtatg gatcgatgca ttatccaatt atattactgc
    12481 actaggatat ggctccgaag atgaaagtct attcgaaaaa tactggcctg cagatgttca
    12541 gatggtcggt aaagaaatcg ttcgctttca tacgatctat tggccaatca tgctgatggc
    12601 ccttgatttg cctctaccta aaaaagtatt tgggcatggc tggctattga tgaaagacgg
    12661 aaaaatgtct aaatcaaaag gaaatgtcgt ttatcctgaa atgcttgtgg aacgttatgg
    12721 tttagatgca ctccgttatt atttgcttcg tgctgttccg tttgggtcag atggtgtctt
    12781 tacgccagaa gattttgttt cccgtgtcaa ttatgatctg gcaaatgatc tagggaactt
    12841 attgaatcga acgattgcta tgatcaacaa atattgtgat ggactcgttc ctgactatgc
    12901 ctcacttgtc actccatttg atagtgaact gtctacgacg gctgctaacg ttgtcggacg
    12961 ttaccatgat gcaatggaaa aaatggaatt caatacagca ttggctgaaa tctgggtgct
    13021 gatttctcgt gcaaacaaat acattgatga aacagaacca tgggtattag caaaagacga
    13081 agaaaagaaa gctgaattga atagtgtcat gatccattta gctgaatctt tgcgtatcgc
    13141 agcgatatta cttcagccaa tcatgacaga aacgccagag aagatcttca atcaactagg
    13201 attggactct gaaacaatga atcttgaagg attacacttt ggcgaatttc cttcaggaac
    13261 aaaagtagtt gcaaaaggta caccaatctt cccacgttta gatatggaag aagaagttgc
    13321 ttttattcaa gaaaaaatgt ctgaaggtac tcaaacaaac gaagatacag tcaaatggga
    13381 tccagaagaa acagaacttg tttcaacgaa agaaaaacaa atcaaatttg atgtatttga
    13441 aaaagtagaa ctaaaagtag cagaagtcat caactgtcaa aaagtagaag gggcagataa
    13501 gttgctgcaa ttccgactag atgctggaga cagccaagac cgtcaaatct tgtcaggaat
    13561 cgctgaattt tatcctgatc caagcgaatt gatcgggaaa aaagtcgtca ttgtagcaaa
    13621 tctgaaacca cgaaagatgc gtggacaaat cagtcaagga atgatccttt ctgcagaagc
    13681 accagatggc tctttacaag taatcgaagc accaaaatcc atgccaaatg gctcagaaat
    13741 cgcatagaaa ttcaaagggg gtatgacact agttgtgtca tacccccttt ttccgaaatt
    13801 tgagaagcaa ttttcgtaaa ttccttctta ttacttgaag ccaatcatat aatacagaaa
    13861 cagagaacta tccaaaataa atcctagaaa aagaagtacg agcttcgctg atttttgtta
    13921 atttagaata atactaatag gaatcgtaaa aacagaaaaa aagcataatg ataaagggtc
    13981 gggcagattt taattgattc atctggtact cttttttatt gtccttacat tcataaagtt
    14041 tgaatgcaat gactttatta catctatatt tatatctaac agtagcgttg atgtgttaat
    14101 tataagttct atcactttat gttcaattag tttgtgctct tatatgtgtg attgaaaata
    14161 tagataaaaa aacaatcatc ggctttgact tcgatgattg ttttctttat tttgtaaaaa
    14221 tcctatcact tgattttatg gtaacctttt atttttgtct tcaaacggct tggtaagaga
    14281 gcagtaagca gtgcaaatgg gatcgaaaag acataccaga aaatcgtacg tccgatacca
    14341 taatgttgat agagctttgt caacatcacg tgtaacaaga tcaaccctaa aagcaaggag
    14401 ccagctataa accaatgatt atcccaatgc atgacttcac taagtgccat cactccaaaa
    14461 ggatagaaat aaaaatagat cccgactaag gtcatccgcc agttctttgt aaatgttccg
    14521 atattcaata aaaagaaaat cgctgaaagc aaaataccga taggcggaaa aagcccaacc
    14581 aaaaaggaat acaacatccc ccacaagatc atcacaggac ctttgatcaa tgcaacgatt
    14641 gcgatgaaca aagtcagcaa tattagtttt tgtgataacg ttgcaacagt cattaatcca
    14701 aataaaatta atgtgaacca atgccaatgg gactgctgtt gttctttacg ggaaaaatcg
    14761 acccggttgg ataaataatc tgctaatttc ggataagaac gcttaaaatc cataaactgt
    14821 tcctccttcg tggaaaaggt aggtttagta tacgaaaaat aaaaaagaaa tacatccgtc
    14881 ttaagaggga gtttttcact gaaagtggag aaaaaagaat ggtaaattaa aatattctca
    14941 gttatactga aaattatacc aaatttcaaa gaagaaagag gatgggaatg aaaggcaaac
    15001 taaaacgaga aatcaatctg tttggcgcat tagctaccgt tatgggaacc gtgatcggtg
    15061 caggcgtctt cttcaaaact gctgctgtta ctgctagtac tcagtctaca agtttgacat
    15121 tgctagcttg gcttttgggt ggtttcttaa cgatctgtgc tggattgaca gtggctgaat
    15181 tagctacagc aatcccggaa actggtggag ctgtaaaata tattgaagct gcgtatggaa
    15241 aattgcccag ctttttatta ggatgggcgc aaagcttgat ttactttcct gctaatattg
    15301 ctgcattatc gattatcttt gcgacacaat tgacgaactt attacaatta tctaccgatt
    15361 atcttttgtt gattgcagtg atcaccgctg tttctgtgac agggttgaat ttgttaggga
    15421 caaaagtcgg tgcttctgta caatcagtga cgttgattgt taaattaata ccaattgctg
    15481 tgattgtcat atggggatta ttgaccccag gacaaggaac tgtccagtta tttccaatcg
    15541 aagctggaaa agatgttact tttgtcgaag gattgagcag tgcgttgtta gcaacgttgt
    15601 ttgcttatga cggctggtta ggtgtcggtg caatggcagg ggaaatgaaa cggccggaaa
    15661 aagatttgcc taaagcaatt attcttggtt tgagttttgt aacagtcgtt tatctattga
    15721 tcaattttgt ttttttgaaa actttgccga ttgatcatct tgccggtaat ttgaatgcag
    15781 cttctgaagc atcagacgtc atttttggag gaatcggtgg aaagctggtc actattggga
    15841 tcttgatctc ggtatacggt gcattgaacg gttatacact aactgggatc cgcgtgcctt
    15901 atgcgatggc tttagaagac gagctacctt tcagtaaaca gctgacaaag ctttcaaaga
    15961 agtttacggt tccttatgtt cctgcggttt tccagttagc agtagcttgt attatgatga
    16021 gccttggttc tttcgacttt ttaacagaca tgttgatttt tgtgatgtgg ctattcagtt
    16081 tactgatttt tatcggtgtc tttattttaa gaaaaaaagc gccggaattg ccacgtccat
    16141 ataaagtacc actttatcca atcgttccga ttattgcgat tctcggtgct attttcattt
    16201 taggtatgac gatgatgacg caaacgaaat tagcattgat cggtataggt gttaccttga
    16261 taggtatccc agtctattat caaaaaaaga aaaaacgctc agaagagtaa aatatttcaa
    16321 caacagacag aaaaagtacg aactaggtcc tctagatctt cgtgcttttt ctatttcaat
    16381 aaaacaagtt cttctatttt gatttttgct acttctgcaa gtagtgctta tgtgctaaag
    16441 taagaatgaa aaggagagat aaacatgata tttgattctc atacccattt aaatgctgaa
    16501 cagttcaatg aagatattcc agaaacgatt cagcgagcac aagaaatggg ggtaacgaaa
    16561 atggcggtcg tgggcttcga tacgccaacg attgaaaagt ctttgcaatt aagccatgac
    16621 tatccaaata tatacagtat tatcggctgg catccgacag aggctggcag ttatacgaaa
    16681 gaaatcgaaa ataaattaca agaacaattg actttaccaa aggttgtagc attaggggaa
    16741 attggcttgg attatcattg gatggaagac ccgaaagaag tccaagataa agtatttcgc
    16801 agacagattg ctatcgcaaa agaaatgaac ctaccaatca gtattcatac tagagaagca
    16861 cttgaagaca cgtatcaaat cctaaaagaa gaagatgttc gagatatcgg tggaatcatg
    16921 catagtttca gtggtgatta tgaatgggca aaacgatttc ttgacttagg gatgcatatt
    16981 tcatttagcg gtgtcgtcac tttcaaaaaa gcattagacg tccaagaggc tgcagcaaat
    17041 gtaccaatcg aacgattact tgtggaaaca gatgcccctt atctggcacc agttcctttt
    17101 agaggaaagc gaaatgaacc aggctatact cgttatacag tagaaaagat tgctgaactt
    17161 cggaatcttc cgacagaaga agtggctgcc caaacatgga caaatgcgca ccgattattt
    17221 ggtctaagcg aacatggata agatgaagat ccaagagatt atagtcgttg aaggaaaaga
    17281 cgatacaaga aggctgcggg aagtagttga tgcagatacg atagaaacaa tagggtctgc
    17341 aatcaatgaa gagatcctga tgcaaattga acatgcccaa gagactcgtg gagtgatcgt
    17401 ttttaccgat cctgattttt caggagaaaa aataagaaaa atcattatgg aagctgttcc
    17461 tcaggcaaaa catgcttttt tgccgcgcac acaagctaaa ccaaagaaaa agggaagcct
    17521 tggtgtcgag catgcaagtg atgctgctat tttagaagca ttgaaaaagg tcgtgacgcc
    17581 agacatttcc caaacggctg tttctgaaat cactagacaa gaccttttag actatggttt
    17641 aatagctggg gcacaagcaa aagaaaaacg agaaaaacta ggtgacgagt tgcgcatcgg
    17701 ttacacgaac ggcaaacaat tggaaaaacg tttgaagatg tttcgtatta cgccgaaaga
    17761 actcgcccaa gcaatgaaaa tagtggagga acaacatgag tgaatatcgt gaaattgcga
    17821 caccctctag aacaaaagag attttattga aacatggttt ttcatttaaa aaaagtttag
    17881 gacaaaattt tctgactgaa ccaaatattt taaggaaaat cgtagaaact gcgcaaatag
    17941 atgaacatac gaacgtgatc gaagttggac caggaatcgg tgcattgacg gaacaattag
    18001 ccaagcatgc aaaacaagtc gtagcatttg agatcgatga tcgtttgatc cctgtattgg
    18061 ctgatacgat gcaaccctat gacaatgtga ctattgtaca tcaagatatt ttaaagaccg
    18121 atttgtcaac agctgttaga gaaacatttc atgaggagct tccgttaaaa gtcgtagcga
    18181 atttacctta ctatattacg acaccgatca tgatgcattt tcttgaatca gatttggttg
    18241 tggatgaact agtcgtcatg atgcaaaaag aagtagctga tcgtatctct gctgaaccag
    18301 gaacgaaagc ttatggttca ttatcgattg ctgttcaata ttatatggaa gccagtttag
    18361 cattcatcgt accaaaaaca gtatttgtcc ctcagccaaa tgtagattca gcgattttga
    18421 aactgacaag aagagatata ccggcagtcg aagtgacaga cgaaaaagca tttttccgat
    18481 tgacaaaagc ggcatttcag caaagaagaa aaacgctttg gaataacttg cagcattcgt
    18541 atggcaaaga tgaccagaca aaagcatggt tagcaaaaag cttggaaaca gctggaatcg
    18601 atccaaaacg tcgtggggag actttgtcat tacaagaatt cgccgcatta agcaatgcga
    18661 tgtcagaaaa tatgcagtaa aaaaagaggt tgtgacagaa gttgtgaaaa agctgtcctg
    18721 catcaagtaa taagaacagc caaacaaaaa tagttcctca tgtttttcgt ttgtttgggc
    18781 ttattaccgc agatgcaagc ttttgaacac cgtttaagaa agaggttgtg ggcctgccgt
    18841 ttaactctaa gtcacaagga acaatttcaa aaaacagctt ctcatgtttt tgagttagtt
    18901 ggtcttatta cttgatgcaa gcttttgacc actattatgc cgaacaagga gatgtgacac
    18961 aaattttgtc acatctccta tttttgtttc ttgatcaaaa aattcttata cttgatactc
    19021 acactcattt tgtatggatt tagaaaagaa tatgtgtctt gacagttatt agtaagtgag
    19081 ttatactaag tcgacattta tgtgtcaaga catattagga gagagaaaaa atgagaaaaa
    19141 attcagttcg aaaactaacg atttctgctt tattgattgg gatgggggtc attatcccaa
    19201 tggtcatgcc taaaatcatg attccaccag cttcctttac tttggcgtct catgtgccat
    19261 tatttattgc gatgtttttt acaccaggag ttgcagtggc tgttgcgcta ggtacgacat
    19321 ttggtttctt tttaacaacg ccggttatca tcgcattgcg agcattgtca catcttgtgt
    19381 ttgcgttgat tggggcttgg tacttgcaaa agcatccgag tatcgtttta aaaaatggac
    19441 agtttacttt tgctaattgg cgtttccaag ggttcaattt tgtgatcggt gtgattcatt
    19501 ctttagcaga aatgctagta gtcagcatct tttactttat tggtaatatg cctgaaacat
    19561 attattctca aggatatttt tatacagtat tcatcttgat ggggattggt gggcttatcc
    19621 acagtttagt tgattataat attgcttatt ttatagcagg aacactcagc aaatattttg
    19681 atatccccgt atttacggca gcaaaaaaag aaaatcggaa agagtcgatt caagggtacg
    19741 cgaagaaaac gacatattag acatgatctc tcaaaaaaaa aactctcatc tagtaatgga
    19801 taataaatcc tctaagatga gagttttttg tcctaaaaag agctgcacca acatcttctg
    19861 gcacagctct aacagggggc aatttatgga agtttgatga cttgttctgt ttctttatca
    19921 aagaagtggc ctttgctgat gttgaaggca aggtcgacta tttcgcctgg tttatggaaa
    19981 tctcttgcat ctacttttga gatgaactca gtagaaccag tttttgtgta aagcatcgtt
    20041 tcagctccaa gtaattcgga aacgacaact tctgatttca ctacggcttc aggtgaagct
    20101 tcaagggcta cttgttcact gtggatgtct tctggacgaa taccgaagat aacttctttt
    20161 ccttcataac ctttttcaac taatactttg ttttttcctt caggaatacg aagcttaagc
    20221 ccatgtccat ctgtgataac accatttttc aatgtcacat taaagaagtt catggcagga
    20281 gatccaataa agccggcaac gaacatattg acgggtgtat cataaacttc tttcggtgta
    20341 ccgatttgtt ggataaatcc gtctttcatg ataacgattc ggtcagccat agtcattgct
    20401 tctgtctgat cgtgagtaac atagatggtc gttgtttcaa gacgctggtg aagtttggca
    20461 atctcagcac gcatggctac acgtaattta gcatctaaat ttgataatgg ctcatccatt
    20521 aagaagactt ttgcatcccg aacgattgcc cgtcccaatg ccacacgttg gcgttgtcca
    20581 ccagataaag cagctggttt tcgtttcaag tattctgtca gacctaagat ctctgctgca
    20641 ttgtccacac gttttttgat gtctgcttta tcatatttac gtaatttcaa gccaaaagcc
    20701 atattatcaa aaacagtcat atgaggatac aatgcgtagt tttggaaaac catggcaata
    20761 tcacggtctt taggtgccac gtcattcatg acttttccgc cgatatttag ttctccttca
    20821 gagatatctt ccagtcccgc gatcattcgc aaagtagttg actttccaca accggaagga
    20881 ccaacaaaaa cgataaattc acggtctttg attgatagat taaaatcagt tacagaataa
    20941 ttttctgcat tgtcatattt tttatatacg tttttcagag ccatttctac cataatacgt
    21001 tccacacttt cttttttagt tttattaact atttaaagta taaatgaaag cgttaactaa
    21061 cttcaatgtc atgttgaaca agaatttttt cttttttttg tcaatgtgct agttttaagc
//
LOCUS       DAIGWC010000049        20661 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.050, whole genome shotgun sequence.
ACCESSION   DAIGWC010000049 DAIGWC010000000
VERSION     DAIGWC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.050"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            112..306
                     /locus_tag="NOB74_001846"
     CDS             112..306
                     /locus_tag="NOB74_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221034.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            575..874
                     /locus_tag="NOB74_001847"
     CDS             575..874
                     /locus_tag="NOB74_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221035.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(971..1405)
                     /locus_tag="NOB74_001848"
     CDS             complement(971..1405)
                     /locus_tag="NOB74_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1221036.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1637..2347)
                     /locus_tag="NOB74_001849"
     CDS             complement(1637..2347)
                     /locus_tag="NOB74_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCI1221037.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2337..3197)
                     /locus_tag="NOB74_001850"
     CDS             complement(2337..3197)
                     /locus_tag="NOB74_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HCI1221038.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3202..3840)
                     /locus_tag="NOB74_001851"
     CDS             complement(3202..3840)
                     /locus_tag="NOB74_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HCI1221039.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3855..4154)
                     /locus_tag="NOB74_001852"
     CDS             complement(3855..4154)
                     /locus_tag="NOB74_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1221040.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4197..5681)
                     /locus_tag="NOB74_001853"
     CDS             complement(4197..5681)
                     /locus_tag="NOB74_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI1221041.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5701..6162)
                     /locus_tag="NOB74_001854"
     CDS             complement(5701..6162)
                     /locus_tag="NOB74_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1221042.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="NOB74_001855"
     CDS             complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="NOB74_001855"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HCI1221043.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7465..8235
                     /locus_tag="NOB74_001856"
     CDS             7465..8235
                     /locus_tag="NOB74_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI1221044.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8508..9335)
                     /locus_tag="NOB74_001857"
     CDS             complement(8508..9335)
                     /locus_tag="NOB74_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1221045.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9903..11138
                     /locus_tag="NOB74_001858"
     CDS             9903..11138
                     /locus_tag="NOB74_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCI1221046.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12137..12397)
                     /locus_tag="NOB74_001859"
     CDS             complement(12137..12397)
                     /locus_tag="NOB74_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCI1221047.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12424..13725)
                     /locus_tag="NOB74_001860"
     CDS             complement(12424..13725)
                     /locus_tag="NOB74_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1221048.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14017..14475)
                     /locus_tag="NOB74_001861"
     CDS             complement(14017..14475)
                     /locus_tag="NOB74_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1221049.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14488..15819)
                     /locus_tag="NOB74_001862"
     CDS             complement(14488..15819)
                     /locus_tag="NOB74_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HCI1221050.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15830..17272)
                     /locus_tag="NOB74_001863"
     CDS             complement(15830..17272)
                     /locus_tag="NOB74_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1221051.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17259..18023)
                     /locus_tag="NOB74_001864"
     CDS             complement(17259..18023)
                     /locus_tag="NOB74_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HCI1221052.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18127..19002)
                     /locus_tag="NOB74_001865"
     CDS             complement(18127..19002)
                     /locus_tag="NOB74_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1221053.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19257..19341)
                     /locus_tag="NOB74_001866"
     tRNA            complement(19257..19341)
                     /locus_tag="NOB74_001866"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19305..19307),aa:Leu,seq:caa)
     gene            complement(19359..19430)
                     /locus_tag="NOB74_001867"
     tRNA            complement(19359..19430)
                     /locus_tag="NOB74_001867"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19396..19398),aa:Gln,seq:ttg)
     gene            complement(19440..19512)
                     /locus_tag="NOB74_001868"
     tRNA            complement(19440..19512)
                     /locus_tag="NOB74_001868"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19477..19479),aa:His,seq:gtg)
     gene            complement(19574..19658)
                     /locus_tag="NOB74_001869"
     tRNA            complement(19574..19658)
                     /locus_tag="NOB74_001869"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19622..19624),aa:Leu,seq:caa)
     gene            complement(19679..19749)
                     /locus_tag="NOB74_001870"
     tRNA            complement(19679..19749)
                     /locus_tag="NOB74_001870"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19715..19717),aa:Cys,seq:gca)
     gene            complement(19795..19866)
                     /locus_tag="NOB74_001871"
     tRNA            complement(19795..19866)
                     /locus_tag="NOB74_001871"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19832..19834),aa:Gln,seq:ttg)
     gene            complement(19878..19950)
                     /locus_tag="NOB74_001872"
     tRNA            complement(19878..19950)
                     /locus_tag="NOB74_001872"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19915..19917),aa:His,seq:gtg)
     gene            complement(19953..20026)
                     /locus_tag="NOB74_001873"
     tRNA            complement(19953..20026)
                     /locus_tag="NOB74_001873"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19992..19994),aa:Trp,seq:cca)
     gene            complement(20033..20113)
                     /locus_tag="NOB74_001874"
     tRNA            complement(20033..20113)
                     /locus_tag="NOB74_001874"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20077..20079),aa:Tyr,seq:gta)
     gene            complement(20115..20190)
                     /locus_tag="NOB74_001875"
     tRNA            complement(20115..20190)
                     /locus_tag="NOB74_001875"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20155..20157),aa:Phe,seq:gaa)
     gene            complement(20226..20298)
                     /locus_tag="NOB74_001876"
     tRNA            complement(20226..20298)
                     /locus_tag="NOB74_001876"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20263..20265),aa:Asp,seq:gtc)
     gene            complement(20308..20380)
                     /locus_tag="NOB74_001877"
     tRNA            complement(20308..20380)
                     /locus_tag="NOB74_001877"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20345..20347),aa:Val,seq:tac)
     gene            complement(20396..20467)
                     /locus_tag="NOB74_001878"
     tRNA            complement(20396..20467)
                     /locus_tag="NOB74_001878"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20432..20434),aa:Glu,seq:ttc)
     gene            complement(20482..20571)
                     /locus_tag="NOB74_001879"
     tRNA            complement(20482..20571)
                     /locus_tag="NOB74_001879"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20535..20537),aa:Ser,seq:gga)
BASE COUNT         6524 a         4329 c         3280 g         6528 t
ORIGIN      
        1 aaaactttca aattgattct ttttatttat cataaagata tagatacata atcattttca
       61 cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca aatgtattat
      121 gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat cagtaacgaa
      181 tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg tgccataaaa
      241 ataaagaacg agctagaaaa agaactgact tgtggtaaag ctgttgtaga tatcatcgaa
      301 aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac aaattgctaa
      361 gattatagaa ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt
      421 ataccatatg attatttcaa tatgtatcct ggaattggag atctcgtaga gctatatcaa
      481 gatgaatcaa atatacttgt cattcatcat gaaatataga gacttataaa attgtttatt
      541 tttataatgt atcagtatag aaaggaaata aaacatggat tatactgttg aatttgacag
      601 tgaactactt aagcaatttc cacaagaaga acatttcatg tataaagaag caatttccca
      661 caaagtgaca gagtatttgg agcataattt ttttcgtata aagccagtgc gtactcgttc
      721 ggcaaaagga atatacgaga tgaaagtcaa aattaataaa aaaaattatc gcatagcatt
      781 tgctttaaaa aaaaatcatg tgttcatttt ttatattagt tcgaatttgc aaaaaattgt
      841 atttgataaa gaggtgagta aaaaaataaa atagctgagc attggaggat agattgagtg
      901 atactaagtc tatcctcttg tttttctaaa gaactaagct agaatttttt cttttgtacg
      961 ttattatatg ttatttgtca ttaccaaaaa gcaccttttt tcttctagta tctatgacat
     1021 aagaaatacc acccatttcc tttacttgaa caaatcctac tgattcataa aatttttttg
     1081 ttttctcagt atcatctgtc aataattcga tttggactgg tccataacta gtgatcttct
     1141 ccaaagcttc attcaaaagc actttgccta ttccttggcg ctgatacctc ggatgaatga
     1201 ggatatcttg aataaatgcg atcgtcgcaa aatcagtgat ccaacgaacg attccgataa
     1261 tcttcccttc cccattacgc tttatcagag attcagattg ttcaaatgct ctagctaacc
     1321 ttgcagtgtc ttttgtgtaa ttcgtccaac caacgctctt atataattca gaaatctcat
     1381 cgatcataag ggaatcaata ttcatttttt tcttcctttc ttatacaatt ctccctctaa
     1441 taatacagtt ctttgactat ttaatctatc acatataact ctcctgtaaa gattctctcg
     1501 attccttaaa attcctcttt ccttttagaa tgcatacttt ttgataaata aaaaggttgt
     1561 gataaatttt cttcacaacc tctgtttctc tctatcaagt gttatctttt aattttctac
     1621 ccttacccta gcatctctat tgcccgtagt atgcatactt tccatgtttg cgaaaataat
     1681 gtttatctag taaatattgc gggatttcac atatattggg gttgatcagc tcgttttctt
     1741 tggccatcag acaaatttca tctaagatca aactgttttc tactgctttc ataggtgaat
     1801 ccccccatgt gaacggtcca tgtccataga caagtactcc agggacttcg tttggatcta
     1861 attttctttc cttaaacgtc tcgacaatca cattccctgt atgaacttcg taagcttctc
     1921 ttacttcttc tttcgttaat tggcgtgtac aaggaacctt accataaaaa gcatcagcat
     1981 gagtcgtgcc ataagctggc aaatcgcgtc ctgcttgcgc ccacatgacg gagtgcgtgg
     2041 aatgagtatg agtaatagca gttatatctt caaaagtttg atacaaaaca acatgtgtgg
     2101 ggagatctga agatggtttt aagctatctt cttctattat atttcccgac aaatctgtta
     2161 ccaccatttg atctgcttgc atgcattcat atctgacacc gcttggctta atgacgatga
     2221 ctcctagctc acggtccact tcactcacat tgccccaagt caatttgact aatccgtatc
     2281 gcggcaatgc cagatttgct tcaaggacac gttgcttcat tgctgcaatt ttttcttcac
     2341 aagacatcat agccagcctc cttcaattta gaacttaagt agtcttttgc ctgctggatt
     2401 tctcttcgaa agtcttggct tttttcactc cacatttcaa tcagaaatgt tccatcataa
     2461 tctagacgtt tcaaatgtct taataatcca agaaaatcaa cacaaccgct accaaaagga
     2521 acatcacgaa actggcctga atattctttt gttacagggt aagtatcttt taagtggata
     2581 gcagtgatat aatcgatccc tttctcaagt tctcgagccg gattattttc cggccatgcg
     2641 gacaaattgc ctaggtctgg atatacttgt agaaaaggtg aatgaatctg ttctttgatt
     2701 tctaaaaatt ttgaaatgga gttcataaat ggatcatcca tgatttccac ggaaagaatg
     2761 atgccatatt tagaagcttc ctttacgctt tcttttattc cttcgataaa gtcttctctg
     2821 gaattcattg atttctcttc ataataaaca tcgtatccag ctatttggat tactttgacg
     2881 cttagattat gcgccaaatg gattgctttt ttcattagtt gtttcgctgc ttttttcttt
     2941 tctggatcag cagaaccaaa cggaaatcgc cgatgcgcac ttaaacaaat cgaatggata
     3001 cgtacaccgg agctgaacat ctcttctctc agctcagcta tcttttcttc agaccaatct
     3061 aatcgtgcta accgctcatc cgtctcatca atcgacatct cgataaaatc gaagtccatt
     3121 tcttttacaa gggaaaaacg ttctttccat gaaatatctt tgggtaacgc tttttcataa
     3181 atcccaattt gagccatttc cttaccccca gatacgaatg atctcatctt tgaagttttg
     3241 tgcggccttc atcggatcat ttgctgctgt aataccacga ccagtgataa aggtatacac
     3301 atcgatccct tcaaataagt gtaatgtgtg tggatttaat ccaccagtta cagaaacatt
     3361 aaagcctagt tcaatcagtt ttttgatctt cgataaatct ttttcacccc aagtttcacc
     3421 agataacagc gcatcacggc tttgatggta gattacctgc cggataccga tgttatgcca
     3481 atccatggct tgttcaaaag tccaattgcc gtagagttct acttgcaatt cacctatttc
     3541 tttttgtgct gcctccatag ttggaatcgt tgcacaacaa atgactgtca tccagtctgc
     3601 tcctgctttt gcaacattac tcgccactgt tcctccagcg tctgcacatt tcgtatcagc
     3661 gactagtttt ttatctggga acatactgcg aatacagcga atcgcttttt gtccttcctg
     3721 taagcaaaga attgtgccca cttcaataat atctactaca tcaccaactt tcataacatc
     3781 tcctaatgca tgttctaagt cattgtgatc taacgcaatt tgcaaattcg gcctgctcat
     3841 cttagttcct tcctttactt gtttttttgg taccactttg tttcagcaaa tttttcactg
     3901 atttctttga ctgacatcac atttttgata ccgataactg taactccttt tttctctgcc
     3961 tgagtaaaca tattcaaaaa attgactggc gtaaaaacta catcgtattg gccagctgaa
     4021 ctttttccct ctgaaatggc acaatgatgg attttggtaa ttggtacgtt tagttctttc
     4081 attgcttttt ccacacttct catcatcatc aagcttgttc ctgatccatt tgcacacgat
     4141 actaaaattc tcatcttaat ccctccatta tgagtgttgt ctaatcagat tttcttttat
     4201 actctctgct tttctgcata tgtgtcatag tcttctacaa tcaaaaaata accatcagga
     4261 tttttccgat attgtaactg cggaatagcc aataaaccaa tgacaactac ggcaattcca
     4321 gcataaccta ggactttcat gattactgta aacaatggcc aagctgttgc ccagtcgaac
     4381 atcccgatat aaccaccgta tgttgacatc ccaatccatg tagcgaataa tgctgaaccg
     4441 cctacttgta tgattcctga aagaaacggg aacaggcaag cggctttgaa tccacctcgg
     4501 ttattggcat aaactgctat aacggcatta tcaaagaaca acggaatgaa accggctatg
     4561 acgatcgttg gtgatttcaa taaaatcagt aaaccaatca tcaaaaactg tcccaaagca
     4621 ccaaacaaga acccaatcgt taccgcattt ggcgaaccaa agccaaaagt agcagctacg
     4681 tcaattcctg gaacagctcc tggtaaaatc gtgtttgaga ttccttggaa agattgagtt
     4741 agttcatcga cgaatgtccg aacacctaat tgcaagatcg ccagatatac cgcaaaattt
     4801 aaagaagtcg tcataatgta gaataagaaa ctctgccctt cttgcatgaa ttgcgcttga
     4861 atcaaataat ctttgcctag tacaatcaga atgatcccaa agaaaaatag catgagtaac
     4921 gaagtagcaa ccatattctc attgaaaatc gacaagaatc ctggtaattt gatatcttca
     4981 atttttttgt cttgcttgat tgatctattt ttcttttcat cccgcttttt catccactca
     5041 gctaattttg caaatataaa gattccgaac atttgctgat gtgccactgc aaatccggca
     5101 ccttctgtca attcctgcgt gattcctact gttaagttag aagctactgt ccaataacaa
     5161 cctaaaatca gtcccataaa aatcaatgct tgtatcctac ctagatcagg aaagcaaaac
     5221 agtaaaatcc aaaaagcggt agctgcttgt tgaacctgaa cgtttccggt agtgaaaacg
     5281 gaacgcagtt tcgtatattt ctgaaaacgg actaataaga tatttaaaac aaatgcaatc
     5341 agtaataaaa tcatcacatc tccaaaggta cggccaaatg tctccattaa tccagcatcc
     5401 acagcatttt gtccaaaata aggatctgta accatggcat ccaaattgaa ccgttccttt
     5461 agtccaacca agattggccg aaaattattg accaaaccac cagagccaac agtcaaaata
     5521 aagtaaccga ccgttgcctt taagaatcca gcgatgcatt catgaagcgg gcgtttcagc
     5581 aaaatatagc ctaataacac gataaaacca atcaggtatg ctggctgcgt caagatattt
     5641 gttgcaaaat acgtccaaat gcttaacaaa aattccccca tcttttttct cctctatcaa
     5701 ttaattatat tctgccatca caacttggta atcatcgatg gagttcgtag agatgagacg
     5761 ctcaaccaat ccatctgtca ttaataattc ggataatttt tggatatttt ctagatgttc
     5821 ttctggatct tttgctgcga gtgtaaaaaa caaactagcc gttttctcct cattctcccc
     5881 ttcactttca aaacggattg gctgtttcaa cttggtaaat gaaatagctg ttccaaaaac
     5941 accatcactt ttttctgaag aatgcggcat tgctacttga ggtgcgatca caatataagg
     6001 accgtatttt tctacacaat ggatgatctc ctccacatac gtttcatcaa taatttcctt
     6061 atcgatcaat acaagacagc tttcggcgat agcttcacgc caatccgtga tttctttatc
     6121 tgggtaatga atcaattgat ggtcaaaaaa gtatttcagc aagaaactcc ccttctttct
     6181 tataaaaacg acggaaacgg tgtatcattt tcaatcgaga agacatcttc aaatcctcga
     6241 taaaaattaa actcaagatc atctttgttt gtcggataga tgaatttccc gcctacttgc
     6301 cagatataag gtttaaatcc atacttcagg cgatcctttt tgaatttcca aatttcagtg
     6361 atctcttttg gatcagccat aaaattagac caaatatcgt agtggacagg aatcactact
     6421 tttgcattca atgactccgc catgcgcagc atatcaacag aagtaacttt gtctgttatc
     6481 cctcgtgggt tttcaccata ggcccctaaa cagacatcga ttttgtgttc attaccatgt
     6541 ttggcaaata aattggagta atgtgaatct cctgcatgat aaagattccc tcctgatgtt
     6601 tcgaataaat agtttactgc aatttgatcc atctcctgag gcatttttcc ttttaatacc
     6661 tcttctggat cttcacaagt gaccaacgct gtccgatcaa acgcttctaa agctactaca
     6721 ttgatgtctt tgattttgac tgcatcacct ggctttactg taatcgtttt ttcttcagga
     6781 attccccatt tttgccacgt gcgaaccact tcttttggcc caatgaatgt tgcttcagga
     6841 caattttgat gaactgctgc ggctgtatgg atatctagat gatcggaatg gatatgtgta
     6901 acgattaaag cgtctacatt ttttatcgca aaaggatcga ttacgaaagg ctgagtacgt
     6961 aaattaggct gcatattttg aacgccactc atacgcatca tctgatggcc ttttttcatc
     7021 atgccattcc catgactacg ttttcccgtc ccacaccata gatcacataa aatattcgtt
     7081 ccttcatgac ttttcagcca aattcccgta cagcccagcc accacatagc aaaagttcca
     7141 ggatccacta cttctgtttc gatttcttca ttcaagtatg tgccccactc aggaaatgtt
     7201 tctactaacc acttttcttt tgttacttca ttgacagttt tactcatttg cttgctcccc
     7261 ccatatcgtt gttccaactt acaagtaaat attaatgtgt atcagcatcc atgaaaaccc
     7321 ttttatatga ccgtttgttt tttatatgat tttctttcag taatcaatga ttgtttcagt
     7381 ataataaaga cagatatgaa tgtttaaatg aacaactagt caaataaatc catggatcaa
     7441 gatgtccctc aggaggcaaa agtcatgaaa aactcacttg tcaatattga aaaacgtcaa
     7501 aaagaaattt tggaactgct tcagcagact gaacaactat caactttcga attagctgaa
     7561 tcccttgatg tatctattag tacgatacga agagatttaa atttattaga agaaaaaaac
     7621 gagatcatac gcaattacgg ttattgttct tataattaca aaaaccagac tgattttgat
     7681 caatctggtc ctgaaaggat taaacaagcg attgccagag aagctagtaa atacattaac
     7741 gattatgata cgctgtttat caattctagc tcgactgcgt tgaaaacact ggattttctt
     7801 caatctaacc atttgacagt cattacaaac aacgtgaaaa tcaattactc tccgcacaaa
     7861 gataattgta gttatatttt aactggtgga gagatgcgct ttccaaaaga agcactagtg
     7921 ggcgacatcg cattaaatac gatttcttca gtcaatgcag acatttgtat cattggctgt
     7981 agcggagtcg atgtagtaca tggggtcaca acaaagatat taaatgaatc aacgatcaac
     8041 gaaatgatgg tcaacaagac aatcaaatgt aagattttag tcgctgatca tcgaaaaatc
     8101 ggactgacat caaagttcaa gattgctgat atttcagtct ttgattattt gatcactgat
     8161 aaattttgtt ctgaaaaagt attagaggag atcagaaata cggggataaa aaccattcaa
     8221 gtagattcat tttaagaacc aggacgtaaa tatgtaaata ggattatcaa aaaaatgaat
     8281 aacaaattta tcgataaatg aaaaacacgc tacgctcaaa ttgataaagg aatcccaaga
     8341 tgtatccatc caatcgatac catcataatc tattgcttct tttataaccg ttatatgttg
     8401 cctaaatagg aatcaaacaa tatcgaaaaa aggaggtatg acaaaagtca cacctccttt
     8461 tttcgaataa acggtattca aatcagaaca ctgatttcac aaccacttta tttcaggtcg
     8521 ttttcaatca cctttaccgc gtaatcattt ccgttgaaac gcgctatttt ttttgcgtcc
     8581 atatatcttt ctaaataatc atcttctcct aattgcttat ggcaagaagc aatttcataa
     8641 agcaagtatt ccaatgcata agtcgattta tgtttcttat tatactcaat acccttctca
     8701 cataattgga ttgctttatc ataatcctcg attttacggt aataggtggc gatatcataa
     8761 tatacaatgc agaccatcag attatcaaaa tcagtctcac tcaatatttt aagtgtacgc
     8821 tccacataaa ctttcgcaaa atctaattct ccttttgaca agtagatcat tgccacgttt
     8881 gcagctgctt gtaagtgatg gatatctgtt tcggtcgttt gttccaacac ttgattaaaa
     8941 taaaataatg ctgcatctgg ttttttcgca taaagatgat caagcagtcc ttgataaaat
     9001 aaaatttgat ttaaaagatc agaattactt actttttcct gatcgatcgt ttgtaaaatt
     9061 ttataagatt cttggtattt tgatacagaa ttcaatgatt gaatctcatt tatttttttc
     9121 ctgattttgt cttcttctgt ttctactaat atatcggaga tctcgacatt cagctttttg
     9181 caaagcgcac ttaagatatt gatgcctggc gacatattct tgttttcgat attgctgaca
     9241 gttgcttgtt cacaaatgcc ttctgctaat tgtacttgtg ttaacccctt tttctttcgg
     9301 tattctttta gtaatgctcc atctacttta atcaaaacaa tttccttccc tttaaaaaat
     9361 tatttctcct ttatatcata cacaaaaaaa agttctaaac aaccaaaaat gtttagaaca
     9421 gaataaaaat tttaatttta aaataatatt caaattaaac aactggcgta tctgctcctt
     9481 gatttctttt tgtgttatct gaataattat cgtttacagt tataacacat agtgaaaatt
     9541 gtcatggcga gaaagtctaa gaatattttt aaacataact atttctttct tacgtgtgta
     9601 taatgacgac agcacaccta tcaattaata taattatttt atttttttat gttctcatgt
     9661 ttatttttaa tgacacaact tctcgtattt atctggcaca acatataaat cgatcaaaaa
     9721 attgttgcgt gtttttttga aaattggagt ttcaacttga ttacaaaatt taaatttaga
     9781 agttgtgaaa acagcgagag acagtttaat attcaaaata tacataggct actcgaacgc
     9841 tgtgtttttt agtatactag taagaaacga agggatagac tcattccaat aaggaggatt
     9901 tcatgaagac aattcttttt gctcctgcag tattcaattt agctgagaca acacgaatga
     9961 ttgaggttgc caaagctatg aaagaccgtt attactgtgt attctttggc ttttctaaaa
    10021 cttttgctcc tttgatcaca gaaagtggct ttgagtatca tttactagcg ccgatcctta
    10081 cgaaaaaaca agaagaacaa atcataaaat ttgaccagtt gcgtacactt aaaaaccctt
    10141 ttaccaaaga aatggttgcc tctcgtatca ctagtgaaca gagtctgatt gctaagtttg
    10201 agcctcgact gattgtgaca ggttcgaatg tgacaatttt tttatcggcc cgcaataaaa
    10261 agattccttt agtatatgtt aaaccctatg ctttgagtga accttttttt caatcagagc
    10321 atgcgctgat gccccacgag ttacgtttct tcggcccttt aagcaatccc ctttggcact
    10381 ggacaaaaaa gcgtatagta aatacccgat ggatccccaa tgccttcaaa cacgctgcac
    10441 aaaaagaaat gcttccttta ccaaaaacaa gtttacaaat gatggatgct gatctaaatc
    10501 tcatcacaac gcctaaacta tttttggaag aagaacagct gccggaaaat tatcgaatcg
    10561 ttggtccaat ttttgctaag ctcagtactt ccttgcctga agaagtgcta acttttatac
    10621 agcgaaagca acaagaaaga aaacgtatta tctatttcgc aatgggtagt tcaggcaatc
    10681 cgcgtatgtt acgcaaaatt ttgttcttct tacaaaaaca accggatcta gcggttattg
    10741 cacctattga ctatctgctt gatgacattc aatctgactc agaagatctt ttaataacag
    10801 aatatctgtc tagtcatctt ttgcatgaat tcattgattt ttcttttatc cacggcgggg
    10861 aagggaccgt ccaaactgcc tgtgaatccg gcaaaccgtt tatcggtgtg gggatgcaat
    10921 ttgagcaaag ctgtaatatt gactattgtg taaaatacgg aaacgcaatc gccctcacaa
    10981 aaccagtgac tgaaagaaaa ctgcagattg ctctgcgcga agtttcttca cccaagattc
    11041 gtcagcaggc acgcacgctg caagccgttt ttccaataaa tggtccacaa caagcaattc
    11101 aagaaatcga aaccttcctg agcaaccacc caatatagtt tcaagtagaa aaagcttttt
    11161 taatagagac tcatcagtaa tttcgctatt cgagacccag acagtgaaaa tacaaaaaaa
    11221 gtaaatagtg gattgaaaag ttagagttac ttaaattacg gtgtctaaaa aacacaaaat
    11281 catccttaaa ataaaagatc tgacgctatc caaatgagca taggtagcgt ctgccattta
    11341 ttcttagtca aattctttga cacctttctc tggttggatc atctcaacgt ttcttcaaaa
    11401 gaaagaccat aataattagg caaatacatt ttcttaaaat gtgtcatata gatctagaag
    11461 catcgctttg tagagatttg tgccgctagt cccctcaaca attactaaat caaatgtagg
    11521 atttaccact ttatctttga taatcaacct ccctcttctg ttgagacaat gatctcgcaa
    11581 tccgatgcat actcctatat aaactgccag caatccccac atattgagta gatcatgtca
    11641 gaatgttcta tgtcgtcagc aacgatacac taaaagtcac gttcaccatg actgattgct
    11701 attcccagca caattatttc tatacacgtt tcatgatttg aataaacact cacatcatac
    11761 atattaccat tcatacacca tactgcagcc cctactatat ggttgtaagc tcccaaatct
    11821 atatttgact tgatcacttt ggtagtagat ctactaattc taaatccatt gctgataaaa
    11881 tttccatttt ttcctccttc tttctgccaa aacagttaaa acaataataa tctttatgta
    11941 aaaaagggct gtgacaaaag ccttgtcaca gtcccatatt ccgaataaac ggtggtcaaa
    12001 agcttgcatc tgcggtaata agttcaacca aacgaaaaat aagccaacat ttcacaaaaa
    12061 tttaagaagc aattttcgta aatttcttct tatttcttga agctaaccac ttctgttaca
    12121 accactttta gaacatttaa agcttcgatg tgacaaacca tctatgctgc tcgatcataa
    12181 aattgatagc aaaaattcca caaagtacat atgtccccca tgaaaacaaa acattcatat
    12241 gcggtacaat gatctttgga agaatcacga tcaaaaatga tgccagtgcc caaatccatc
    12301 gattgatttg aatatgatat gtagctagca tattcaatat aaggtgacta gccgttaata
    12361 aaaagataaa aacaaaaaat aaaatcagcc aatacattgt ttcccacctt ctaaaaacca
    12421 aacttagaca gtctggactt cgttttctcc acgactttgt tcatctgaca gcatcttttt
    12481 atcataagct tttacaaatg gataatagat aataaatgct atcaatgtgt tgatcatgat
    12541 caagataaca acacgccagt catttcctgc tgaaagataa ccgccgattg gagctggtaa
    12601 tgtccatgtt ggcaaaacag taaatctatt gaccatttct aatttgactg caaaataact
    12661 gataatagtc aaaactaaag gaactaagtt gaacgggatg aacatgtaag gattcaacat
    12721 cataggagct ccaaaaatta tgggctcatt gatattgaag ataccaggaa taatagaaaa
    12781 acgaccaacc tctttcaaga attttgattt acagaagaat ataaacaaaa cagataccac
    12841 gatcgttgct cctgcaccac caattgttac cgtccattga taaaactgtt caggagcgat
    12901 atagggtaat tgggtggcag ctgtaccatc tgccaatgcc tttgcattct catccaacat
    12961 gatcagccac attggacgaa caacagcccc tacaatactc atgccatgga taccaaatga
    13021 ccacaacaaa tggatcaaaa acattggtag taaaacacca agcaaattat tccctaaaat
    13081 attggttaaa ggctcgaata acgataataa ggcagcgttt acatcaaagc ccgcgacgct
    13141 tcgaatcagc caagtaattg ttaaaatgac tgcacctgga atcaatgcct caaaactacg
    13201 ggcaacagca ggtggcactt gttctggcat tttgatagta atatttcgat ttttaaagaa
    13261 acgatatact tccactgcaa aaatcataga taagatcccc gcaaacatcc cagatgctcc
    13321 caaagaactc ataggtaaga cccagccaag aggtgcctct tcaggagtta aaacgtttac
    13381 aggaacttgt aacataaaga acgttcctaa agataatata ccacctgtca cactatctaa
    13441 tccatatgat ttagctagat ccgaacccat aacaaaagtt gcataaatag ccatcaatcc
    13501 catcgtcatc ctaaagggta aaacaatcgt tgccgaataa ggggcaataa attcattcca
    13561 tccaggaaac ggtaaattga taaagaccat aaaaaatgtc ccaatcaaaa tcaatgacaa
    13621 tgttgaaaca accccattac gaattgctaa taaatgacgc tgtgtaccaa tttttgccat
    13681 tggtgggaca agtttctctt cgacccattt catcagcttt tccactaaaa ccactccttt
    13741 tcaataaaat atgaaccatt cattgcatga caacgcaaag aatgttcata actaattata
    13801 taattaagaa attttatttc aatatattct cttaaataat caaatttatt tttaagaatc
    13861 ctgaaaataa gttttctaaa tcataggagc aacaaaaaaa ttcgataatt aacaaaaatc
    13921 aaaatgatta aatctagtga ttgaaacata tcatttcaaa aaaattttgt aaattcaccc
    13981 ataaatatca ccctatttaa cttttttcat cgtacactaa aattcaaaac aactatcttt
    14041 aatctttact tcttggtttt gttttaataa atttccttca aaaatgcctg gagaaactac
    14101 aatgatcacc gtatcttttt gtgcttgctc caacttcttc aaatctataa tagctaacag
    14161 tgtcccttct tttacctcct ggttactttc aacccgtatc tgaaacggac ttccttcgag
    14221 ttcaactgta tctaaaccca tatggatcag tatttttctg ccagattcac tttcgatcgt
    14281 tatggcatgt cgggtaggaa atatattatc gattattcct ttaactggcg catggatata
    14341 tccatcatga ttcgttatag cgtatccaac tcctatcatt tttgaagaaa agacctcgtc
    14401 ttttactgct gttaatggaa taatttgacc actagctaca gcttttagaa tgtttcttgt
    14461 tttaaagaaa tgcacttttt atcacctcta ctttaatgct ggccaatatt ttttgtttac
    14521 tttgatcatt tcatctagta ttttttttgc gactctggca tttggtacgg tttgattcaa
    14581 tgtaaatgct tgtaaagctt tttgataaga accttcaaag taagcatcta ctagtaactt
    14641 ctctactgca acttgtgcct ccatcaatcc tttatgaaaa tcactgattg gttttcttag
    14701 tgtaattggc tccacaccag ttgcaccaac atatgccggt atttcaacaa ctgcatctga
    14761 ccgtagattc ggaatcgccc cttgattagg aacgattagc ataaagcgac gacgatcatc
    14821 attcaacaag gaaatagcta tatcgacgat atattgtcca tgctccccaa aattaaagtt
    14881 caatacttct tccacaatac cgcggcgtat tttatcagcc atttctttgg tatttttctc
    14941 tcgtccatcc atgaccatat tagcacgtgt atactctttg tcagtatgct caacgaccat
    15001 atcaggatat aagtaatact ctaagtaatt attcgggata ttacttggaa aatttttcgt
    15061 gatgactgac atcatttgaa aggttttttg ccaagtttta tctcctatat taaaatcggc
    15121 gacttgcatt tcttttgtta ttagtttttc aataatctct ggcataattt ctcgttgcaa
    15181 ttctttatca taaatcgatg tataccagcc aaagtggttt aaaccataat acgtaacgat
    15241 ccaattctta cgatcataac cgtaattcac tgcaatcgtt tcttcaattg aaatagtcat
    15301 atcacaggca ttaatcattt ttacattcgg atatttacga cgaacagctt cagaaacgat
    15361 cgactctgga tttgtataat tcaaaatcca tgctttgggg gcatagtctt gtatatgatc
    15421 gacaatttcc aataaacctt tgattgagcg catcccataa gcaaatcctc cgagtccaca
    15481 cgtttcttgt cctactaatc catgtttaag tggaatcttt tcgtcctttt ctcgcatctc
    15541 caatcctcca acacgaattt gtgagaaaac aaaatcgcat cctgtaaaag caagctttgg
    15601 atcatccgtt gcacgaatgc gaatatttga aaaacctttt cttttcagca taaatttaac
    15661 aatcaagtac atatccatat ttctttcttc atcaatatca tataaacgta tttcagataa
    15721 tggcaaccgt ttttcattgt tcaaaatggc ttgaacgatt cctggtgtat acgtactccc
    15781 gcctccagct atagtgataa tctgtttttt catcatcatc ttttcctttc tattcttcta
    15841 ataatttatt gaattctgcc ataacataag tcacttctaa gccgatgata atttgataat
    15901 ttttttcagt tggtttaatg atcccgctta tccctaattg cttgattcgc tgttcctcga
    15961 ccatggtggg atccactacc tctacccgta ggcgtgtatt acaactatag acatccagga
    16021 tattggcttt tcctccaaac gcttgtagca tttttgttgc catatattca taatttttac
    16081 ttgctaaccc taactctgtt tcttctaagg ttacttcatt gccaaactct gccttagctt
    16141 cacgtcctaa tgtctgaatg tttctcttat tgatcaaata ataaaaagta acgtaataca
    16201 aggcaaaaaa gaaaattccg attggaagaa tcaaaatagc attggtagcg attcgaaaat
    16261 tgatgagata atcaacaata catgctccga atgtaaaacc aattcgtata ttgaataagt
    16321 aacagacaat ccctgctaaa ccggcaaaaa gtgcatggat cacgtacaac ataggagaaa
    16381 gaaacatgaa actaaattca acaggctcag tgatatttgc aataaatgaa gttcctgcac
    16441 cgcttcccat gattcctttg accatctctt tattttcttt ataagctgct ttatagatag
    16501 ctagacatat agctggtata ccaaacatca ttactacaaa aaaaactgat aaaaacagtc
    16561 cagcctgagg atctccgttg ataaagcgtg tcatctctcc tctgaaaact tccttgctag
    16621 gagatgtata gcttcctaaa tcgtaataaa tatacgtatt caacacatgg tgcagtccaa
    16681 aggggatcag caaacgattc aaaaacataa atatccccac acctaatgct cccatatcaa
    16741 cgagcagttt tgcaaaatta tcaatcccaa tttggatgag cggccagata aagcccaaaa
    16801 aaacagctgc gattgtttgt agaatcatca ccatagtcaa tgggaatttt tcgcccgcaa
    16861 aataagaaaa aactactggt aatttttgtt ctttaaagcg attatacgtc catgccgcta
    16921 ctaaaccgga aataattcca ccaaaaatcc ccatattcac ttctgggtcc ataatttcta
    16981 agcctttttt caaggtagca atcgctaaaa aaccagtaag tgcaggtatt cctttgtcct
    17041 tatttttgac aaaaccgatt gcaactccta tagcaaataa gatatccaag tttccaaaaa
    17101 cggcatttcc agctgcacca attactggga tgttcagcat atcgtcagct gataaacgca
    17161 tgatcaatcc cgctaatggc atcgctgcaa ctggaagtag catcgctctt ccaagcttct
    17221 gcacatttga tttaacattc atttttattc ctcctctatt aaatatcctc atatgttact
    17281 aactcaatca aaggatcatt tttcactttt tgagcaaatg ctgaatgaat taaaaattcg
    17341 acttggtggg tacgaggata cacaaaactt gaaccattta acaattcctg atccaaatac
    17401 gctgcgtgac acatgacttc gatcgtttta tcttctctca atatcatgag taaacttgcc
    17461 aaatattctt ccacactcgt attgatttgt cgtttttttt catcagtttc tcctacgaca
    17521 tcgaaacaag gctcaaaata atcgacatga cgaacttcat cttttcgttc aaagttgctc
    17581 cgaaccggca aatcatattt ttttgctaat gtaacaacta cctcctgatt ttcatccaaa
    17641 gtatgagtat gatgatgact gtctaaatga gttggtatga tccccgcatg ataaattttt
    17701 tgaatctgag cattccattc ctgatacagt tgatctttgt caatgttaaa tggatgctga
    17761 taataagata aggatctgaa ctctccgctt tcgataagag tatcgacagt tttgaggagt
    17821 ggtttgccac acgtcaatgt taaatggact cctacaccta gcctaggcat ttcctttctt
    17881 agtttcacag catgctcgaa acccggcata tttgccatca atgtagttga tgtcaaaatt
    17941 cctcgctgat aagcatccat aatcccataa ttcacaccat ggctatagcc aaaatcatcc
    18001 gaattaaaaa tcacttttcc catttcattc tccttctttt ttctactaaa ataggcgcaa
    18061 ccaaataatc atagtccatt tactatgtgt catttggttg cgcctataga tagttacgcc
    18121 cttattttaa tagattcttg ctagatgaat tgccaaatag atgatttcat tttcttgaat
    18181 ggcaagttga aattgctgtt cgatgatatc tttaatcttt agtgctgtac aatacgcttt
    18241 gctatgttta aatgtttcag taaaaaaacc aatattttct actggcgttt cttcctgata
    18301 aatcaagcgt ttaaccagga atttgatatg aaccattaag cgatgataag tcagtgattc
    18361 tttatcataa acgtttgaat aggatttttc tagatgggac aaaatcgtgg tcgtcatttc
    18421 tactattttt aagctcttta aactattagg ctctcctagc tcagcattaa tgatatgcat
    18481 agtgatgaat cctacttcat ttgaccctaa ctcggtttga tatcgatgat tgattcgctc
    18541 gaccacttct actgctatat catattcatt tggataaagg aatctcattt ctggcaacat
    18601 aattgctgtg acatctctat cttctctttt tcgttgaata gcaaaataaa tatgatctgt
    18661 caatgtaata tagatatttg aatctaatgg agaggagatc ctagctgtta tcagttcaat
    18721 cacttcttcc gcaaaatcca taaattcgat tggaatctgc gagactatct cactgaatcg
    18781 tttgatcttt tctttagaat ctaatacaaa taatttgtca gcatcctcaa catcaaatgg
    18841 cttactcact ttagcagaaa agccaatccc tttccccatc gcaatttttt ctattccatc
    18901 gtcatcgatc aatacagcat tatgattcag ctttttcatc acatacaccg ttaattcacc
    18961 tcctctatat gataaaacaa aacaacttgc agactccttc atacatattt ttgtctccaa
    19021 acaattttta aagacaaaaa acgacctaag aaagaaccct ttcttaggtc gtgcctaatt
    19081 gaatagtagc accctacata atttacaaaa atagtttaac acataataaa agcgttatca
    19141 atatcttttt tactcgtttt atgataatac ttgtatcgaa ttgatttgga ggtaattaca
    19201 taaaaacaaa aaaaatatag caactctcta taagaaagtt gctatattga taattatacc
    19261 ggcggccggg gtcgaaccgg cacgtcctca acggacactg gattttgagt ccagcgcgtc
    19321 tgccaattcc gccacgccgg caaatttaaa aataataact ggggtagctg gattcgaacc
    19381 aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca agaataaagg
    19441 gcgaatgatg ggaatcgaac ccacgaatgc cggagccaca atccggtgcg ttaaccactt
    19501 cgccacattc gccatcataa aagatgttat ttaatttctc aataaaaaac taagatgaag
    19561 acatcttagt caataccggc ggccggggtc gaaccggcac gccctcaacg ggcactggat
    19621 tttgagtcca gcgcgtctgc caattccgcc acgccggcaa gttgatttat tagtactaag
    19681 gcggtaaccg gatttgaacc ggtgatgaag gttttgcaga cctctgcctt accacttggc
    19741 tataccgcca ttatactatt atcaatctat aaaataaaga ataaattata gaaactgggg
    19801 tagctggatt cgaaccaacg catgagggag tcaaagtccc ttgccttacc gcttggctat
    19861 accccaagaa taaaaagggc gaatgatggg aatcgaaccc acgaatgccg gagccacaat
    19921 ccggtgcgtt aaccacttcg ccacattcgc catggcaggg gcagcaggaa ttgaacccac
    19981 actaacggtt ttggagaccg ctgttctacc tttaaactat gcccctataa aatggaggag
    20041 agtggattcg aaccactgaa ccctaaggaa cggatttaca gtccgtcgcg tttagccact
    20101 tcgctactcc tccatggtgg cgcgggacag aatcgaactg ccgacacacg gagcttcaat
    20161 ccgttgctct accaactgag ctaccgcgcc atattttaaa attattaatt gaataacaag
    20221 aacgacggtt ccgacgggaa tcgaacccgc gatctcctgc gtgacaggca ggcatgttaa
    20281 cccctacacc acggaaccag ttcattatgg aggttaacgg gatcgaaccg ctgaccctct
    20341 gcttgtaagg cagatgctct cccagctgag ctaaacctcc aacattcaat taaaatgacc
    20401 cgtacgggat tcgaacccgt gttaccgccg tgaaagggcg gtgtcttaac cgcttgacca
    20461 acgggccagg taaatttgct acggagagta agggattcga acccttgaga cagtttggca
    20521 ccatctacat gatttccaat catgctcctt cggcctctcg gacaactctc cagagtgaaa
    20581 gaagctcaat actctttctc aaaatgagaa ctccggcagt aggactcgaa cctacgacat
    20641 catgattaac agtcatgcgc t
//
LOCUS       DAIGWC010000050        20361 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.051, whole genome shotgun sequence.
ACCESSION   DAIGWC010000050 DAIGWC010000000
VERSION     DAIGWC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.051"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            292..1431
                     /locus_tag="NOB74_001880"
     CDS             292..1431
                     /locus_tag="NOB74_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HCI1221054.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1498..2073)
                     /locus_tag="NOB74_001881"
     CDS             complement(1498..2073)
                     /locus_tag="NOB74_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI1221055.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2078..3052)
                     /locus_tag="NOB74_001882"
     CDS             complement(2078..3052)
                     /locus_tag="NOB74_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HCI1221056.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3076..3120)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3335..4303
                     /locus_tag="NOB74_001883"
     CDS             3335..4303
                     /locus_tag="NOB74_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1221057.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4416..4694
                     /locus_tag="NOB74_001884"
     CDS             4416..4694
                     /locus_tag="NOB74_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCI1221058.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4812..5048
                     /gene="secG"
                     /locus_tag="NOB74_001885"
     CDS             4812..5048
                     /gene="secG"
                     /locus_tag="NOB74_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HCI1221059.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5151..5906
                     /locus_tag="NOB74_001886"
     CDS             5151..5906
                     /locus_tag="NOB74_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1221060.1"
                     /translation="MKRVKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSL
                     AEHQLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5909..8266
                     /gene="rnr"
                     /locus_tag="NOB74_001887"
     CDS             5909..8266
                     /gene="rnr"
                     /locus_tag="NOB74_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HCI1221061.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8288..8752
                     /gene="smpB"
                     /locus_tag="NOB74_001888"
     CDS             8288..8752
                     /gene="smpB"
                     /locus_tag="NOB74_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HCI1221062.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9054..9773
                     /gene="atpB"
                     /locus_tag="NOB74_001889"
     CDS             9054..9773
                     /gene="atpB"
                     /locus_tag="NOB74_001889"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HCI1221063.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9826..10041
                     /gene="atpE"
                     /locus_tag="NOB74_001890"
     CDS             9826..10041
                     /gene="atpE"
                     /locus_tag="NOB74_001890"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HCI1221064.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10132..10656
                     /gene="atpF"
                     /locus_tag="NOB74_001891"
     CDS             10132..10656
                     /gene="atpF"
                     /locus_tag="NOB74_001891"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HCI1221065.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10643..11185
                     /locus_tag="NOB74_001892"
     CDS             10643..11185
                     /locus_tag="NOB74_001892"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HCI1221066.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11208..12764
                     /locus_tag="NOB74_001893"
     CDS             11208..12764
                     /locus_tag="NOB74_001893"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HCI1221067.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12778..13680
                     /locus_tag="NOB74_001894"
     CDS             12778..13680
                     /locus_tag="NOB74_001894"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HCI1221068.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13703..15109
                     /gene="atpD"
                     /locus_tag="NOB74_001895"
     CDS             13703..15109
                     /gene="atpD"
                     /locus_tag="NOB74_001895"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HCI1221069.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15123..15545
                     /locus_tag="NOB74_001896"
     CDS             15123..15545
                     /locus_tag="NOB74_001896"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HCI1221070.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16014..16244
                     /locus_tag="NOB74_001897"
     CDS             16014..16244
                     /locus_tag="NOB74_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HCI1221071.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16341..17642
                     /gene="murA"
                     /locus_tag="NOB74_001898"
     CDS             16341..17642
                     /gene="murA"
                     /locus_tag="NOB74_001898"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCI1221072.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17655..17831
                     /locus_tag="NOB74_001899"
     CDS             17655..17831
                     /locus_tag="NOB74_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCI1221073.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17966..18262
                     /gene="yidD"
                     /locus_tag="NOB74_001900"
     CDS             17966..18262
                     /gene="yidD"
                     /locus_tag="NOB74_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HCI1221074.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            18326..18709
                     /locus_tag="NOB74_001901"
     CDS             18326..18709
                     /locus_tag="NOB74_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1221075.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            18878..19762
                     /locus_tag="NOB74_001902"
     CDS             18878..19762
                     /locus_tag="NOB74_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI1221076.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            19876..20112
                     /locus_tag="NOB74_001903"
     CDS             19876..20112
                     /locus_tag="NOB74_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HCI1221077.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            20200..20280
                     /locus_tag="NOB74_001904"
     tRNA            20200..20280
                     /locus_tag="NOB74_001904"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20234..20236,aa:Tyr,seq:gta)
     gene            20287..20358
                     /locus_tag="NOB74_001905"
     tRNA            20287..20358
                     /locus_tag="NOB74_001905"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20319..20321,aa:Gln,seq:ttg)
BASE COUNT         6758 a         3566 c         4426 g         5611 t
ORIGIN      
        1 tttttttgca actagcttct gtatatgatg tttacaaaga atggtacaag aaaagatcat
       61 ccttgaaaaa ggaaagctaa caataactag catcatataa gagcttttaa ggatagaaca
      121 gtagaatagg aatctatggg caagtcctct cgtataaata aaataggagg gaagtagcag
      181 catatttttc ataaagtggc tctctttctt catttttact ttggttgctc ctatttgaaa
      241 attcgagcac actcaaatac aataaaaaga aatggcaagg gagaggatta gatgaaaaaa
      301 gaagaaaaaa tcgcgatttt acaagagatt atccgaatta aatcagtgaa tggaaacgaa
      361 ggtgaagtag cagcctattt gaataagctt ttggcaaggc atgacataac aggagagatt
      421 gtttcttaca gagatggtag agataatttg attgctcgtt accaaaaggg ccaatcagga
      481 aaagtgttag gcctatctgg acatatggat gtcgtggcgg ctggtgatga atcgtcttgg
      541 acctatgcac cctttgcagc agaaatccat gggaaccgtt tgtacggacg tggtgctaca
      601 gatatgaaga gtggcttggc agcaatggtg attgccatga tcgaactgaa agagtcagga
      661 aaaccattta acggaacagt caaattatta gccactgtcg gagaagaagt gggtgaacta
      721 ggtggggaac agctcacgaa agcaggctat gtagatgact tagatgcctt gatcatcgga
      781 gagccaacca attacagttt gatgtatacg cacatgggat caatcaacta tacagtcacc
      841 tcgcacggaa aagaagcgca tagctctatg ccagaccaag gttataatgc aatcaatcac
      901 ctaaatgaat tcattacgaa agcaaatgct gaaatgaatc acctcgctga aacaatcgag
      961 aatcctgtcc taggaaaaac aatccataat gttacattga tcagtggcgg gaatcaagtc
     1021 aacagcatcc caagccatgc gcagctccaa gggaacattc gatcgattcc agaataccca
     1081 aatgataaaa tcattgcatt gctgcaatca atcgtcaatg aattgaatca agagacagac
     1141 tatcatttgg aattgatgat cgattacaac aaaatacctg tcaaagctga tccagattct
     1201 cctttgattc attccattca gcaacaattc agccagccat tacctttagt tggagcggca
     1261 gcaacaacgg atgcagccga atttacgaaa gctaaccatt ccttcgactt tgtcgtcttt
     1321 gggcctggtg tcgttacttt gcctcatcaa gtagatgagt atgttgaaat cgataattat
     1381 ttggatatga tcgaaaaata tcaaggaatt attttatcct acttagcgta agattttttt
     1441 aataaatgaa aaaacagagc cagattagca ttattttgct aatccagctc tgtttattca
     1501 gcctattttt ctttttgaat atatcaagcg ttggggcaac atagtgatga ctaatgaaac
     1561 aacgacgata gacaacaagc gatcaaggta gtctgtaccc acctgtacca agatcacact
     1621 tgttgtctga cttaaaccta acccatgtaa tagctgaacg atcatactgg atcctgagga
     1681 ggtgatcccg ccaaataact gaacggtaat gatcgaagaa acgatcgttc caggtaccga
     1741 caaaatcaaa gcgagtaata acagtttcaa gctgttttta tctttgccga gatatcttgg
     1801 caaaatcaat ccagcaagca agcctgtgag aatttggatt ggcgaataat acagagaaaa
     1861 aatatctgta gtcactccac ttaaaatacc gctggacaat cctgtcagca ttccaggtac
     1921 aggcccaagc aatgcaccag caaaaatcgt tccgatagaa tcgagataga ttggcaaacg
     1981 aagccataaa gcaatcgttc ctccaatata attgatccca atacacaaag ccatcactgt
     2041 aagtacgcga gttgccattt tgtttttatt cattttgtta gcccatcttt aacctttcca
     2101 aatctttcat aatcgtttct tcttgtgcat ttaaaagaac ggttaaaaac tttcggaaaa
     2161 aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc caaaattcat
     2221 aacgatcaac caatgtttgt ccgcgactta ttccttgagt ttctacagca gtgaagcttt
     2281 taaagccttc acagatggac tcatcgataa aataagcaac agctaatgga tcattgatga
     2341 cacatcctaa gattctttct tgtttccagt gaaagtcaaa ataaaaacga gtgatcgctt
     2401 ttagatactc tccctcttca ggattcattt ggcagcaata ttcaaggata gtcggtgtca
     2461 agacgatttc tcttgtcaca tctaacccaa ccatttctat cggttgtttg agcttttcga
     2521 atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact ggtgaacagt
     2581 taccatggct tttgtaagtt ccgcccattg agacaaaacg atccatatgt ttcccaacag
     2641 atgggctgtt tttcaaagca gaagcgatat tggtcaaagg ccccaaagca atgactgatg
     2701 tatctgtttt ttctttgaaa taatcagtca gaaaatcaac tgcatggagc gattctgcct
     2761 gtttggctaa gaccatcggg aaatttgtgt cccctaatcc atccaaccca tgagtgtctt
     2821 gcgcactaat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca gggatatcta
     2881 aacgatcaca gcgctccaaa catttcagca cattctgcgt accgatatct acagggacat
     2941 tcccgcaaac gacggtaata gcaactactt cgatatcagg ggatttgaca gctagtgata
     3001 aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tactttacgc attatttcca
     3061 atctcctttc tttagagata cttagttttt tattctggga agtttccgaa ccagtccaag
     3121 acgagtgtct tgtttataat gcacgaaatt agtatactgg cttttattgt gaatgtaaat
     3181 gctctcttac aagtaaatct attgagaaga actttaagta aatgatacaa tgaaaaagaa
     3241 atggaattta cgtgtgccga agaaaaagaa tcctattgat cggtatattg tataataaat
     3301 agattatagt ttggcagaaa gcggcgggtg tacgatggtt attttttatt tcattcttat
     3361 tctgatattt ataggaatca gttaccattt tctttcttat ttttatgcaa agaaattagt
     3421 aagagcgggg gtacagagag gctatgactg gtatgaagaa actgggcacc gcttgatgga
     3481 tcctgctgca gtcacgtcag tagaaaaaaa gcgacaaaaa ttagaagaag agtgtgaaag
     3541 cttctgggaa caaggaatac cgaaaacgat caaaagttat gacgggttga aactagctgg
     3601 acagatgttc ctccaaccaa ctcagcagaa taaatgggtc atttgtgtac atgattatcg
     3661 aagtacaggg aaaagagata tgtctcatat aggtaaaaga tatgcagaga aaggattcaa
     3721 cgttcttata cccgatttac gtgcgcatgg agaaagtgaa ggagaaatca tcggaatggg
     3781 atggctagac cggctagatt taattgcatg gatccaactc atcttagatg aacaaccaga
     3841 tgcatccatt attttgcacg gcagttcgat gggcgcttct actattatga tggcaagtgg
     3901 tgaaaagctt ccatctgcag tcaaaggatt tatcttagac agcggatatg tttctgttta
     3961 tgcggaattt cggtatatgt taagtaaaat cacggtcttt cctaaaaaaa tgatcatgag
     4021 atatgcgaat cactatgctc agaaatacgc aggttattct ttaaagcaag catcagctac
     4081 aagacagctt ggtagtaacc atttgccttt gttagtcatc catggtgaaa gagatcattt
     4141 tgttcctaca gaagcagcat acacgattca aaacgctacg gcaggggata aagcattact
     4201 gcttgttcca gaagcagaac atttggaagc atcgatgaaa gatccgaaaa cctattggac
     4261 agtgattttt tcatttattg aacaaagaat aacgatggat tgattttctc ttcctttttg
     4321 taagcaacac gaggataaat aattgtttat agaccatgag actgttaaaa taaggtagga
     4381 ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagag gaaaaaaatc
     4441 gtcttgcttt attcaatgat gagcaacaag aaatcggaga aatgacatgg tcggatgcgg
     4501 ggccagacat catgatcatt gaccatacat ttgtcgatcc agcatatcgt ggtcaaaaat
     4561 tagctgaaaa gctagtgtat actggagtag aactagcaag acgagagggg aaaaagatta
     4621 tcccttcatg cccttacgca aaaaaagagt ttgagaagaa accagagtat catgacgtct
     4681 tacgccaatc ataataataa cagctgaaag atttgcactt tcagctgttt ttccatttat
     4741 atagagttgt cacggagttt tatctatgat aaagttaaag agacgatatc ttttgggaag
     4801 gaggctgcta tatgtataat ttaattttgg gaatcgtgat cgttttatcg attgttatgg
     4861 tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca tttaccggcg
     4921 gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc atgcagcgat
     4981 caactgcagt catgggagct gtctggatga tcttattatt tgtcctagca tttttatctt
     5041 cgaagtagtc gaataagcct ctcgcacaac ggcgggcggc tttttttatt gcaaagagaa
     5101 cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag gtgaaacgag
     5161 tgaaacaatt accaaaaccc ctttatgcaa aacatggaaa acgagcagtt ttgctgcttc
     5221 atgcgtactc aggaagtcca aatgatgtcc ggatgctcgc acggttttta gaaaaagcag
     5281 attatacagt ctatgcgccg ctatttaaag gacatggaac gatggagcca tatgatatct
     5341 tgcaagaaaa agcagaaagc tggtgggcag atactaaaaa agctatccat tttttacagt
     5401 ctgaacagtt ttctgatatt gccgtattgg gattatcgat gggtggcatc tttgctgtac
     5461 gggcactaga agaagaatca gtaattggcg gcggtttttt ctgttcgccc ctgtctcctg
     5521 tagaaacaaa cgtgcctgaa aattttgaaa aatatgtacg tcaagtgctg aagatagcag
     5581 gcaaatcaga aaaagaaatc aatgaaaaag ctgtgtctta ccgctcgtta gctgaacatc
     5641 aattaatgga tatacaagac caagcagcaa tcgcagaaag tagactatca gatatccaac
     5701 agccaatatt tttagctcaa gctgggaaag atgaaatgat cgacccaaat ggtgtatttg
     5761 aaacggcacg caaattgagc cgccaacgag tgacacttca atggtatcct gaaagcggtc
     5821 atgtgattac agttggcaca gcaagacgcg aattagaaaa agacgtgttg gaatttttag
     5881 aaaaattacc ttggaatgag gaataaatat gacaaaagaa acaataaaag agaaaattct
     5941 ctttttcatg gaaagcagtc gcaaacgtag tttttctatg gaagaaatcg ctgaaggtct
     6001 aggctttcaa aaaagcgatg attttaaatt actagtacaa acgattgctc aaatggaaag
     6061 agaacagagt atcgttttca ataaaaaagg aaaagtcaaa cttcctttaa aaccgatctt
     6121 ggtcgaaggg acatttcggg caaatgaacg aggatttgga tttgtaacga ttgatcccga
     6181 agaagatgat atctatatcc cgaaagaagc gactggcttt gcaatggatg gggataccgt
     6241 agcaattgat atcatgaagc gagcaaatac agatatggat cgcggagcag agggaaaagt
     6301 agtggagatt cgagaccgag cgactactca gttagccgga gaatttgttg cttattcaga
     6361 cgaagagata caggaaacgg atctttatgg tgtggtcatc ccgaaagata gaaagcttaa
     6421 ccaattcaaa gtgtatgcag cggcagaggg agttcgtcca gttgacggaa gtattgtatt
     6481 gatcgaactg acccattacc ctgaaaaagg gtatgcaact agtttagaag ggataatcaa
     6541 gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcgattg tcgtggctaa
     6601 cggtattcct acaaaatttc ctgatgatgt gttatctgag gcagatgaag ttccagacca
     6661 gatcagcgaa aaggatattg ttggacgcag agatttaaga gatcagctca tcgttacgat
     6721 tgatggagaa gatgcaaaag atctagatga tgcagtgacg gtcaaaaaat tagaaaatgg
     6781 taattatttt cttggagtac acattgcaga tgtatcttac tatgtgacgc aaggcagtca
     6841 actggacaga gaagcatacg aaagaggaac aagtgtctat ttgaccgatc gagtgattcc
     6901 gatgatccca caacgtttat ccaatggtat ctgttcattg aatccccatg ttccacgact
     6961 caccatgagt tgtgaaatgg agatcgatcc aaatggacaa gttgtctctc atgagatttt
     7021 tccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc aaatcttaga
     7081 agatcaagat gaagaaacga tgcaacgtta tgctcagctc gtgcctatgt tccaagaaat
     7141 gggtgaattg catcgaatcc ttgaaatgat gcgaatcaaa cgtggagcga tttcttttga
     7201 ggatcgtgaa gcgaagatcc ttgttgatgc tgaaggacac ccaaatgata tccagctaag
     7261 aagcagaggg ataggtgaac gcttgatcga atcctttatg cttgctgcca acgaaacggt
     7321 agctgaacat tataataaat taaatcttcc gtttatttat cgaatccatg aacagccaaa
     7381 agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc tggtccgagg
     7441 aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag tagaagacaa
     7501 accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag cacgctattc
     7561 agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact ttacatctcc
     7621 tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca gtgaagataa
     7681 aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag atcatagttc
     7741 taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga agaaagcaga
     7801 attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg ttgtgaaatt
     7861 cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca atgaattgaa
     7921 acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa gaactggtct
     7981 gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc cagatgaacg
     8041 agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac gtccaaaagc
     8101 acgcaatgga aaatctggaa aacgagaagg aaaacaagca ggcaaacgct cagaaaaaaa
     8161 tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga aaaaagggaa
     8221 aaagccattt tacaaaggtg tcaaaaagaa gaaaaagaaa aaataaaatg agttggagga
     8281 aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag ctcgccatga
     8341 ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg agatcaagtc
     8401 gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca acggggaagc
     8461 tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta atcatgatcc
     8521 gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg aaaacgaatt
     8581 gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg gctatgccaa
     8641 ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag atttgaaacg
     8701 aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat aatttcatta
     8761 tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg ttagcattta
     8821 atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg tgcatgggga
     8881 aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga aaatgttttg
     8941 aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg aaaaaaccag
     9001 atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat ggattggatg
     9061 aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt tgtataatgg
     9121 tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga aatcttaagt
     9181 tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt cgaggaatcg
     9241 taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca tttacattgt
     9301 ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc ttacctaacg
     9361 aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact ttggcattta
     9421 taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa ggatatttcg
     9481 taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt gaagaattta
     9541 caaacttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg gaagttttgc
     9601 taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca ttagcaattc
     9661 cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa gcatttgtct
     9721 ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa taatactcgg
     9781 ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa ttatatcgca
     9841 gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg tcaagttatc
     9901 tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt ccgtacaaca
     9961 atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt tatcgccttg
    10021 attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat cgtttgttac
    10081 tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc tatgctgaat
    10141 caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt tgtcagcggc
    10201 tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat cagcgatatt
    10261 ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca atctcgcatc
    10321 aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg ttctgatgca
    10381 gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa tattttgaag
    10441 gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat cactgtagaa
    10501 cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct tcaaatcgcg
    10561 gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat caatcaatac
    10621 attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa gacgttacgg
    10681 gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct atcaagatct
    10741 cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt taagtgatgt
    10801 tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg gttatgatgg
    10861 aatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg accttttgtt
    10921 catgattgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat tgggaagtgt
    10981 cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga atgttgcaaa
    11041 aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta ttattggtgg
    11101 cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc aattagaaaa
    11161 aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg gccatcaaag
    11221 cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac gtgctttcag
    11281 tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca catggtttag
    11341 aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga atggcgcaaa
    11401 acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc attcgtgaag
    11461 gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag gccttgatcg
    11521 gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc gttactgaca
    11581 aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct gttaacgaac
    11641 caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc ggacaacgtg
    11701 aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgattgat acgatcatca
    11761 accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa gattctacag
    11821 ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca atcgttgtga
    11881 atgccggtgc gtctcaacca gcaccattac tttatatcgc accatatgct ggtactgcaa
    11941 tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat gatctttcaa
    12001 aacaagctgt tgcttatcgt gaactttcct tgctacttcg ccgtccacca ggtcgtgaag
    12061 cttatcctgg ggatgttttc tacttgcact cacgtttatt agaacgtgca gcaaaattaa
    12121 gtgatgatct aggcggcggt tcaatgactg ctttgccatt tgttgaaaca caagctggag
    12181 atatctctgc ttatatccca acaaacgtta tctcaatcac tgacggacaa atcttcttag
    12241 aaagcgactt gttctacgcg ggtactcgtc cagcggttga tgccggacta tctgtctctc
    12301 gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact ttacgtctag
    12361 acttagcaag ttatcgtgaa ttagaagcat ttacacaatt cggttctgat ttggatgcgg
    12421 caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa caaaaactgc
    12481 atgcaccgct agctgttgag aaacaagtag tgattttgta tgccttgaca catggattct
    12541 tggacagtat ccctgtagac agtattttag acttcgaaca tgaattattc gaatatctgg
    12601 ataccaatca ttcagatatt tttgaaacaa tccgtacaac aaaagatctt ccagaagaag
    12661 aaacgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca aaaggaaata
    12721 attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt gagatgaatg
    12781 ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac gagccaaatc
    12841 acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc ttcttcacag
    12901 aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac tgctactcag
    12961 ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag catgctgctc
    13021 agccgtcctg tgaagaaaac cggttatatc gtcatcactg cagatggcgg tctggtcggt
    13081 ggatataaca gttcgatatt gaaacaaacg atgtctattt tagaagaaga ccaccaatca
    13141 cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt taaagcacgc
    13201 ggtatcaacc tagcatatga gctgcgcaat ttatctgatc agccaagctt tgatgaagtc
    13261 cgcaaaatcg taaatatggc aacaactatg taccaaaacg aagtattcga tgaattatac
    13321 gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga aaaaatgctg
    13381 ccaatctcag acttagatcc agaagaagca acgactttcg aacaagaata tatttttgaa
    13441 ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag tttgatctac
    13501 ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc aatgaaaaca
    13561 gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttataa ccgtgcaaga
    13621 caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc actagaatag
    13681 tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa tcggtcccgt
    13741 tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg cattagttgt
    13801 ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag aattagggga
    13861 cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag gaatggaagt
    13921 cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag gtcgcgtatt
    13981 caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg cggaaagaag
    14041 cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag aaattttgga
    14101 aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga aagtcggact
    14161 attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc ataatatcgc
    14221 ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc gtgaaggtaa
    14281 tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca tggtgttcgg
    14341 acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt tgacgattgc
    14401 ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca acattttccg
    14461 tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt ctgcggttgg
    14521 ttatcaacca acattggcaa cagaaatggg tcaattgcaa gaacgtatca catctacgaa
    14581 aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact acactgaccc
    14641 ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac gtaaattaac
    14701 agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg ctttagcacc
    14761 tgaaatcgtg ggagaagaac attataaagt agcaacagaa gtccaacacg tattgcaacg
    14821 atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat ccgatcaaga
    14881 aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa actttaacgt
    14941 ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa cagtgaaagg
    15001 attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt tccgaagtgt
    15061 tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga aaggggtgcc
    15121 ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc tatgatcacc
    15181 atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg cctaaacatg
    15241 caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca gattcagata
    15301 cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat aatgttgttt
    15361 caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt gcggaacgtg
    15421 caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat acgaacgaat
    15481 tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta tctaagcact
    15541 cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag gttatgacag
    15601 aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca aatttttgtg
    15661 aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatca gaggttgtga
    15721 aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct catattttgc
    15781 cgttttttga gctaataccg agggtcagat gattgaacac cgtttatttg gaataaggga
    15841 ctgcgacaag acttttgtct cagtcccttt ttttgcatat ttttagcatt tatttcctaa
    15901 aaaatgtaag gggattccta tatttttaag tatacttgtt tttcctttta tacattttat
    15961 ggtattatca ttttattagt tattataaaa caatcgttag aaaggacgtc attatgcaag
    16021 tatacggaat tgatgcggtg cttcgaatcg tgagtcattt ggcgtttatc tacttagcct
    16081 tctggtcttt acgttcgtta cgcattgaaa cttttttcag accaatgcat aatacgcaaa
    16141 ttagaatggc aatcgtactt ttttcaattt ttttagggta cactgcaagt aattttttct
    16201 tagaagttat cgctttatgc cgaaatcttt tcgttagcct gtaaatttta aaaaaaggta
    16261 ctattttaaa agcaaggatg ttataataga aaagattttg agtaagtgta tgctcattgg
    16321 aattttttgg agggaacaac atggaagaga tcatcgtaag aggtggcaat caattaaatg
    16381 gaacagtaag aattgaagga gctaaaaatg ctgttttgcc tattttagct gctagtttgt
    16441 tagcagaaga aggtattacg acattagaca acgttccgat tctttctgat gtcttcacta
    16501 tgaatcaagt gattcgtcac ttaaacgtag atgtagattt tgatgaacaa aagaatcaag
    16561 taacaatcga cgcttcaaga caattagaaa tcgaagcgcc ttatgagtat gttagtcaaa
    16621 tgcgtgcttc aatcgttgtg atgggtccgc tacttgccag aaatggacat gcaaaagtag
    16681 ctatgcctgg tggatgtgcg attggtaaac gaccaatcga tttgcattta aaaggatttc
    16741 aagctttagg agcaaaaatt attcaaaaaa acggctatat cgaagcaatt gcggatgaat
    16801 tgatcggtaa cacgatttat ttagatttcc ctagtgtggg tgctactcaa aatatcatga
    16861 tggctgccgt aaaagcaaaa ggaacaacca tcattgaaaa cgtagctcgc gaaccagaaa
    16921 tcgttgattt agcaaacatt ttgaataaaa tgggcgctca agtctatgga gctggtactg
    16981 aaacaatgcg tattgaaggc gtggatcatt tacatgcagt caaccactca atcgtacaag
    17041 atcgtatcga agcaggtacc tttatggttg ctgctgcaat gacacaaggc aatgtgctga
    17101 ttgcagatgc tatctctgaa cataactgcc cattgatttc taaattgatc gaaatgggtg
    17161 cagaaatcat tgaagaagaa ggcggagtcc gtgtcatcgg accaaaacat atcttaccta
    17221 cagatgtaaa aacgatgcct catcctggtt tccctacaga tatgcaagct caaatgacag
    17281 ctatccaatt agttgcagaa ggtacaagtg tggtgactga aacagtgttt gaaaatcgtt
    17341 tccaacattt agaagagatg cgccgtatga acgctcatgt caaaatcgac ggaaatgtag
    17401 caatcatgga tggaaaccat gaattgcaag gtgcagaagt atatgcaaca gacttgcggg
    17461 cagcagcagc attagtttta gctggcttga aagcaaatgg aatcacacgt gtgcgtaact
    17521 tgaattatct agaccgtgga tattataatt tccatatcaa actacagcaa ttaggtgcag
    17581 acgtcgaacg tgtagacatg gatcaaactt ctgctgaaaa aacagcacaa acgattgctt
    17641 aaggaagtgg ctgaatgagt aaccaacgat atatcttatt aactttgata aagattttag
    17701 tggtgatctt attgcttatc cttctttttg tggccggaac gatgatcgga tatggtgtca
    17761 tcggtggcgg caatccattt aaagtattcc agccaagttt gtggattcat attcgagact
    17821 tttttcattg ataaataaga atcacagtgg ttctagtcga tatgaagtga gccatgaagc
    17881 agaacatgat aaaagaaaac agaagggaac gttgacgtta gtcgcgatcc ctttttttag
    17941 taaaagaaaa gaaggaatct aattgatgaa gaagatattg atttatttag ttagaggata
    18001 tcagcgcttt atttcgcctg catttccacc tagctgccgt tattacccaa cctgttccaa
    18061 ttatatgata aaagcaattc aaacccatgg tgcgctaaaa gggacggtaa tggggactgc
    18121 acggatctta cgctgtcatc cttttgtcaa aggcggtatc gattatgtac cattgacatt
    18181 ccgattaacg cgaaataaga aagataaaaa agaaccagat tataaaaagg ttgtgaaaaa
    18241 tacgggtagc actgagcgat aaagaaaaag aggaaattta ttgtcaaagt aacaactccg
    18301 caactactta tatgggggac aaaaaatgat cgaagaacta aacaagaaag atttaccatg
    18361 gtccttgtta ttagatgcag atcctgataa agaaaaagtt caagtatatg tttccagagg
    18421 gagtggctgg atatggaaag aaaaagaaaa aacaataggt gtactgatct atgtggcaag
    18481 ggaaaaagaa tacgaaatcg tcaatgtagc agtaacccca acgtatcaag gaaaggggat
    18541 tggcggaaaa ttacttgaga cagcttttca gaagctttca cagctagctt caaaccaaac
    18601 tcggatcatt atacgtactg gcactactag tagcgctgcg ttacacctct atcaaaaaat
    18661 gggctatgtg gagattggtc gagtcaaaga ctattttatc catcattaat ctgagcccat
    18721 ttttgaaaat ggagatcaat taagggatca agtgatttta gcaattcact tacctaaaaa
    18781 tagctttaac taataaactt tcaattcgag aaaatgcttt caaatgctaa atagatacat
    18841 tacaatagct ttagcaaaca aaaaggagaa tatttttatg ggaatattag tttttgattt
    18901 tggtggatcg gctgtcaaat atggttgttg ggatggcaaa gagattaaag gtaagggaca
    18961 atttgcaacg cctgaatctt gggaagaaat gaaaacgcaa ttatttcaag tttataaaaa
    19021 aatactcgtt tcttttgaag tcgaaggaat tggaatcagc tctcctggag tagtgaataa
    19081 tgagaaacag gtgattgagg gaatcagtgc gattccttat attcatggat ttaatatttt
    19141 ccgagatttg gaaactctgt ttcaactccc agtaacgatt gaaaatgacg ccaactgtgc
    19201 cggaatggct gaattttatg aaggtgctgc ccgtgattat caagatgttg cttttgttgt
    19261 ggcaggaact gggattggcg gggcgttgtt cacgaaagga caaataaata aaggggcaca
    19321 tctttacggt ggagaatttg ggttgatgtt cttagatggc gataagacat tcagtaaact
    19381 tggtacagcg gtacagatgg cttggcgtta ttgtgaacgc aaaggtctcg ataaaaatgc
    19441 ttataccgga aaagatgtct ttgaattagc agaaactgga gatgcaatag caaaagaaga
    19501 agttgagagt ttttatacgt atcttacaaa gggattattc agtattcaat tttcgtttga
    19561 tccagaagtg atcgtattag gcggcggggt ttctgcaaaa gaagggctca ttgatgagat
    19621 caaaagccga atgaagaagc tgacagaaca attcgatctg catgatttcg aaccgcagat
    19681 tttattatgt gagtacagaa acgatgctaa tcttgtaggt gcagcagcaa actatctcgc
    19741 tgtacgtcaa ggagagaatt aagagcttta gagaaggtgc agcttgcata aaagaagaga
    19801 atgaaatgaa taggagattt ttacctaagg aatgttttat ttgctgcagt atgataaaat
    19861 atctgagagg tgaaaatgat gtcaaaaaaa aataaagata ttgaagtgcg tatagaagaa
    19921 gtgaaaaaag atatcaaagg taagaattat gaagtcactc agttatttat agggaaaaaa
    19981 atgattggtg agatcttagc ctatgggcca aaagaatatg aaattttctt tggtgaagaa
    20041 gattttggaa aagaaaaaag tcttgaaaat gcgatagaaa cagtgattcg acactggaat
    20101 ctgcacgaat aaaaaaatat caaaaaaact ttcaataaag ggttgcaaaa atctggaaga
    20161 ttaggtatta taactaagtc aggttgatac aaacctttcg gaggagtagc gaagtggcta
    20221 aacgcgacgg actgtaaatc cgttccttag ggttcagtgg ttcgaatcca ctctcctcca
    20281 tttcattggg gtatagccaa gcggtaaggc aagggacttt gactccctca tgcgttggtt
    20341 cgaatccagc taccccagta t
//
LOCUS       DAIGWC010000051        20285 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.052, whole genome shotgun sequence.
ACCESSION   DAIGWC010000051 DAIGWC010000000
VERSION     DAIGWC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.052"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            140..460
                     /locus_tag="NOB74_001906"
     CDS             140..460
                     /locus_tag="NOB74_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221078.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            912..1112
                     /locus_tag="NOB74_001907"
     CDS             912..1112
                     /locus_tag="NOB74_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI1221079.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1259..4048
                     /locus_tag="NOB74_001908"
     CDS             1259..4048
                     /locus_tag="NOB74_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI1221080.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4095..4622
                     /locus_tag="NOB74_001909"
     CDS             4095..4622
                     /locus_tag="NOB74_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HCI1221081.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4643..5833
                     /locus_tag="NOB74_001910"
     CDS             4643..5833
                     /locus_tag="NOB74_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI1221082.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5873..7171
                     /gene="asnS"
                     /locus_tag="NOB74_001911"
     CDS             5873..7171
                     /gene="asnS"
                     /locus_tag="NOB74_001911"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HCI1221083.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8224..8898
                     /locus_tag="NOB74_001912"
     CDS             8224..8898
                     /locus_tag="NOB74_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI1221084.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8895..9236
                     /locus_tag="NOB74_001913"
     CDS             8895..9236
                     /locus_tag="NOB74_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221085.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9266..9625
                     /locus_tag="NOB74_001914"
     CDS             9266..9625
                     /locus_tag="NOB74_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HCI1221086.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            10149..12230
                     /gene="cadA"
                     /locus_tag="NOB74_001915"
     CDS             10149..12230
                     /gene="cadA"
                     /locus_tag="NOB74_001915"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCI1221087.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12541..14007
                     /locus_tag="NOB74_001916"
     CDS             12541..14007
                     /locus_tag="NOB74_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1221088.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            14622..15161
                     /locus_tag="NOB74_001917"
     CDS             14622..15161
                     /locus_tag="NOB74_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HCI1221089.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            15235..15675
                     /locus_tag="NOB74_001918"
     CDS             15235..15675
                     /locus_tag="NOB74_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HCI1221090.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            15688..15897
                     /gene="copZ"
                     /locus_tag="NOB74_001919"
     CDS             15688..15897
                     /gene="copZ"
                     /locus_tag="NOB74_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HCI1221091.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            15897..18083
                     /locus_tag="NOB74_001920"
     CDS             15897..18083
                     /locus_tag="NOB74_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HCI1221092.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            18103..20274
                     /gene="copB"
                     /locus_tag="NOB74_001921"
     CDS             18103..20274
                     /gene="copB"
                     /locus_tag="NOB74_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HCI1221093.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6777 a         3527 c         4407 g         5574 t
ORIGIN      
        1 aaaaagaggt tgtgacgtgg tcacgacctc tttttgacga ttatgataca aaaaacatca
       61 tttatgaaca aaatgtgaat aacgggcgtt cttgagatat gattttaatt gggaaaaact
      121 tatcgataag gaggtcttta tgaaaaaaag actgttatgg tgtttgctgt ttctatccct
      181 aagtttaaca agtcagccag tttttgctga agaaacacag cggtctccta ttacaggcac
      241 acgtctgtac aaaaatgttt atgtacagac aacagatctt gattctgcga ttcctgaaac
      301 agaagaacgg tctttgcagc caagatttgg ttacttttgg tactgtccga cctgtgatta
      361 tgaaagttgc tggcatttct tacattctac agctgcagct tttgctttta ctcatactca
      421 gaaatatgat ggacatcatc ctgttattta tgaggtatag atatgagcaa aaaagaaaaa
      481 ctaatctcgt tgatcgtatt ggtttgcctt gttcttctgg taactgtcat aggctatcag
      541 aaataccatg agaacatcag acctactaaa gaatcttccc cagcctcgac cgttgaaaca
      601 gaaccgataa gtagtcagaa agaataattt ttttagttta aagaagaaca tcagagcaaa
      661 aaaacaccaa ctgaacaata tgtcgtttat tttaaaaaaa gttcggtttt tcactttatg
      721 taatcgctga gaaaactttt tttaataaaa aaagtcgaaa aactctagct tttttgtaaa
      781 cggtatgata tactatagga gtagtttttg ttcggtaatc tgtggtagct tgtttcaaat
      841 aaacatcttc cagatataca ccattcaagt aattgcaaaa tatgtgttga tacacaagga
      901 ggatttttat tatggaaaca ggtacagtaa aatggtttaa ctcagaaaaa ggatttggat
      961 tcatcactgc agaaaacgga aacgatgtat tcgttcattt ctcagctatc caaggcgacg
     1021 gattcaaaac tttagaagaa ggccaagcag taactttcga tgttgaagaa ggccaacgcg
     1081 gacctcaagc aacaaacgtt actaaagctt aattaaccta tactaaaaaa taaacgccca
     1141 gacatttgcg tgtctgggcg tttttgtcta ttttctttaa aaagcgatga gagtattttt
     1201 ctgcactttg tagtataatt tcaaaagaac attagaggca ggagaagagg aagatatttt
     1261 gaaaccaaga acttatgcag tcgttgatat cgaaacgact gggacgaatc caaaagaaga
     1321 tcggatcatc caatttggct gcgtcatgat tgaatcaggt cggatcactt cacgtttttc
     1381 gatcgatatt catccagggc ggaagatttc aaaacaaatc cagcatttaa cagggatcac
     1441 gaatcaacgc gtccaaaaag cgccttattt cgaagatgtc gcccaaacga tttacaatct
     1501 tttggcagac accatatttg tcgcgcataa tatttatttt gattataatt ttttgaacca
     1561 tgaactcatg cgatgcggac ttcctagttt gaagatacca ggcatcgata cagtagaact
     1621 tgcacaaatt ttcttgccga cggaaccaag ctttcgctta gctgatttgt cagaaagcct
     1681 tggatttatt catgagaatc ctcatcaggc agatagtgat gccgaagtga cgggtcaact
     1741 tcttttgctg atcgaagaac ggatgagaaa attgccaatc atcacgttag agcagattgc
     1801 gcgattaagt agacacacag gtatggatac gagtcgtttc atttatcatg tgattgaaga
     1861 aatgaaagaa aaaccagagc cacttgatcc ctcattagaa atcgtcgatg ggctagcttt
     1921 gcagaaaaaa gaagtggaac tattcacatc cgtccattat ggcgagcgga catatccaag
     1981 aaaaaaacaa gcaaaagaaa aaatgtttgg taaaacactg atgtatcgaa aagaacagaa
     2041 cagactgatg aatgcggtct acgaccattt cacaaaagat gaatcaaaag atttgatgat
     2101 cgaagcagct acaggaatgg gtaaaacaat cggttatctg ctgccattga gttatttggc
     2161 tacacctgaa aaacccgctg tcatcagtac cgtttcgcta gttttgcagc agcagatcat
     2221 agaaaaagac attccattgc tgaatcaatt gctagatcag cccatacaac ctgtaattat
     2281 caaaagctat cgccactata ttgatttaca gcgttttaaa ggcacacttg tggaaccgcc
     2341 agaacaaaaa caatatgctt tgtatcaaat ggcggtctta gtttggctga cgcaaacgaa
     2401 gaccggtgat ttggatgaat tacatttaac aaatttgaac cattcattct ttgcagatat
     2461 cgcgcacaga ggtattggat ttttagcaag aaatcagtca ttttacgaac aagactttgt
     2521 tcgtttcttg caaaagaaaa tcaggcaaag taattttttg attgtcaatc atgcgttttt
     2581 aatacaagaa acacagcgaa aagaaccatt gcttccagct agtccatttt tgttgatcga
     2641 tgaagtacat catttgccgg aaatcgctga aaaagtaaat gacaaacgat taagtattaa
     2701 ctatttccat aaacaaatcc agcaattaga agaaccaaat cagctgtttg accgaataca
     2761 aagctattta ccgaaagaac atgaagcctt acgctggtta tcgatttatc gagaagaact
     2821 ttctgcgcta tgcgaagcac agatttgtat ggcagaagga ttaatgagtt tagtgagcgg
     2881 caagcaacct aacggacagt atccagaaga agtcatgatg acaaaagaga tgttggatca
     2941 gctgccactg gaatctggga cagccattga tcacctgcag cttttttatc aggagatcca
     3001 gcagctacag tcacaaatgc gtctgacttt tgagattatc caagaaagct ggacaaacca
     3061 gatgcggatc gatttagcaa gtttatatag cttatttgat caattagaca agcagtactt
     3121 gctgatggat caatggctgg aagactggcg agatcatttg atccattggt tcgttcctgg
     3181 gaacacagcg cagcagatga tttttcatct ccatgatttt caagcggcta tgttgccgtc
     3241 gactgtttgg tatcctcgat atgatcgtat tctttatatt ggaggaacgc tgaagatcgg
     3301 ccctaatcga cactatctct ctaagcggct tggcattgaa gcagcacctc ttaaagtgat
     3361 tgcctctcct tatgattatg agaaacaggc aaggatctat gtgccaaaag aggcacctgc
     3421 cgtccatcaa gtcagcaatc aagcatatat cgattattta gagacagcac ttacaggtct
     3481 gatcgaacaa gaagatcggc caatacttgt gttattcact tctcatgatg ttttgcagaa
     3541 ggtctatcag aaaatgcatc tgtctatgct agaaaaagga cgagaaatac tagctcaagg
     3601 gtttggcgga agccgggaga agcttttgaa acgcttcatt ttgtcagaaa aaagcgtatt
     3661 gtttggcgct gacagctttt gggaaggtgt agatttgcct ggggatgctt tgcagatcgt
     3721 tgtagtcaca cgtttaccct tcgataatcc gcttcgcccg atggtcaaag ctaggaacgc
     3781 ttatttagaa tcagagggga tcaatccttt ttaccaggaa tccgtaccta aagcagcttt
     3841 gaagttacgc caagcattag gtcgcttgat aaggacggag acagatcgtg gcgtattgct
     3901 tattttggat cgaagactag tcactgcaaa atatggtgca cggatcatcc atgcattacc
     3961 gaaaaaagta ccgatcaaag agctagctat ggaggaaatc tatcaggaca tccatgaatt
     4021 cttaaagaaa aatgaagaag gaagttagag gagctgtctt ttttcataat taaaatctgc
     4081 tataatgaaa aggaatgaag ataaaggagc gacgaccctt gaagaaaaaa cagacaaagg
     4141 aaaaaacgat taatcgcgtg ttacttggct tgatcgtatt tttattagcg gtcatcgtga
     4201 tcagctcgat tttttacttg cgttccagtc gtccggcggt gcaggcgaag aaagaagcag
     4261 tagaaatcgc aaagaaatat gcaaatcttg aggaagccga tcatttttat tggtttactc
     4321 gaaagaagac atacttttca ctgacaggta caaatgataa aggaaaagaa atcgccgtta
     4381 tcattcctaa atctggtgaa aaagtaaaag tattggatca aacaaaggga ctgactgaaa
     4441 acgaagcaaa acagacaatt gctgcggccc atcctgaaat ccaaatcgaa aaagctgctt
     4501 tagggatgta tgatgatcag cctgtgtggg aagtagtagg aaaagaaaca aatgggaaac
     4561 tgaattatta cctgattggc tttgaatctg gagatgaagt caagacaatc aagggaattt
     4621 aaaaggtaaa ggaatgaatg ggatggagtt atcaaaaaga acaaaacgat tagaaccgtc
     4681 tgtcactttg gcagctgcgg caaaggccaa ggcattaaaa gcaaaaggca gagatgtgct
     4741 gagtttgact gtgggagaac cggattttgc gacaccagaa aacatccaag aagcagcaat
     4801 cgaagcaatc cgcaacggga aagctagcta ttatacacca acagcaggaa tcccagagct
     4861 tcgacaggca atcgttgatt atctgaagaa aaactatgga cttgtctatg aaccttcaca
     4921 aacagtcgta acagacggag cgaaatttgc tttgtatacc cttttccaaa cgatccttga
     4981 cccgcaagat gaagtcatca ttcctgtgcc ttactgggtc agttacggtg agcaagtaaa
     5041 actggcagaa ggacttcctg tctttgtgaa aggggaagaa tccaatagct ggaaagttac
     5101 tgttgaacag ctagaacaag cacgttcaga aaaaacaaaa gccgtaatca tcaattctcc
     5161 atcgaatccg actggaatga tttatagcaa gaatgaactg caggcaatcg gtgaatgggc
     5221 agtaaaaaat gatattttga tagttgctga tgatatttat ggtcgtttag tttataatgg
     5281 caatgagttt actccaattg caacgatttc agaagcaatc aaaaatcaga ctatcatcat
     5341 caacggcgtg tctaaaacat atgcgatgac aggctggcgc attggttatg cggtgggaaa
     5401 tcctgtgatc atcaatggaa tgatcgctgt tgcttcccag tcaaccagta atccgacagc
     5461 agtcagtcaa tatgcagctg ttgaagcatt gaaaggcgag caagatacag tggaagaaat
     5521 gcggaacgcc tttgaagaac gcctgaatac gttatattcg cttgtggcag aactgccggg
     5581 tgtttctctt gaaaagccac aaggagcttt ttatcttttt cctaatgtaa aagaaacgct
     5641 acgcatgtgt aaatatgaaa atgtcacaca atgggtagaa gatcttttag aagaaacagg
     5701 ggtagcgctt gtgactggcg aaggctttgg ggcaccagaa aatgtccgca tgagttatgc
     5761 tactgatcgc gctacgttag aagaagcggt acgcagaatc aagcaattta ttgagagtaa
     5821 aagtcaaaat taatcctaaa gaaattcaag gaatataaaa ggagagtcat acgtggaaca
     5881 aattcaaatc atcgattcga aaaaccatgt gggagaaaca gtaacaatcg gcgcttgggt
     5941 cgcaaataag cgatcaagcg gaaaaatcgc atttttacaa ttaagagacg gaacagcctt
     6001 tttccaaggt gtagttgtaa aaagcgaagt gtcggaagaa gttttccaaa cagctaaaaa
     6061 tctacaccaa gaaacatccg tgttagtaac tggagaaatc cgtgaagaca gtcgttcaaa
     6121 atttggttat gaaatcggaa ttacaaatgt ggaagtggta agcgagagcc acgattatcc
     6181 gatcacacca aaagaacacg gaacagactt cttgatggat catcgtcatt tatggctgcg
     6241 ttcttcaaga caacatgcga ttatgcagat cagaaatgaa atcattcgtg caacgtatga
     6301 attctttaat caacatcatt ttgtcaaaat tgatccgccg atcttgactg gttctgcacc
     6361 agaaggcact acggatctat tcgaaacaaa ttactttgat caaaaagctt atttatctca
     6421 aagtggccaa ttatacatgg aagctgctgc tatggctttc ggaaaagtct tttcattcgg
     6481 tccgactttc cgtgctgaaa aatcaaaaac acgacgtcat ttgatcgaat tctggatgat
     6541 cgaaccagaa atggctttca ctcatcaaga agaaagttta gaagtacagg aacaatatgt
     6601 agcattctta gtacaaaatg ttttagatca ttgcgaatat gcattagatg tactaggacg
     6661 agacaaagaa gtcttaaaaa cttatacaaa attgccattc cctcgtatta cttatgatga
     6721 tgcgatcgaa ttactgaaga aaaatggatt tgatgacatc gaatggggcg aagactttgg
     6781 ttcacctcat gaaacgttca ttgcgaattc attcgaacag cctgtcttta tcctaaacta
     6841 tccaaaagcc atcaagccat tctacatgaa accacatcca acaagagaag acgtggtgat
     6901 ctgtgcagat atgatcgcac cagaaggtta cggtgaaatt attggcggaa gcgaacgggc
     6961 aacagactat gatttcttgc tagaacaaat ccgtaatcac ggtttggatg aaaaagaata
     7021 ttcatggtat cttgatctac gtaaatacgg ttctgttccg cactctggtt ttggtctagg
     7081 tcttgaacga acagtcactt ggattgctgg tatcgaccat gtacgtgaag ctattccatt
     7141 cccacgtttg ttgaaccgaa tttatccata agaggtgatg aaaaagctgt tctgcatcaa
     7201 gtaattagaa cagccaagca aaaacagctg ttcatgtttt tgaattggcg ggacttatta
     7261 ccgcagatgt aagcttttga ataccgttta gtggagaggt tgtgaaaaag ctgtttagtt
     7321 tcgagtatta agaaaaattt tgtggaaatg gctttccaca tttttgcata aatttggctt
     7381 aataccgaga aactggcttt tgaacaccgt ttaaggaaga ggttgtgcgc ctgccgttca
     7441 gctccgagtc acaaggagta atttcaaaaa acagtttttc atgtttgatg actattgtga
     7501 cttgtgaccg aggagttggc cggagagcac cgtttattct aaaaaagaac tgcgaactct
     7561 cgcagttctt tttttaaaat acgggataaa ggaagtttcc agcagacaag agaagaaagc
     7621 aaaagaaatt gctatttgat tcacaaggtt ctataacgaa atcgcaatca atcaaacatt
     7681 tacaaagaag gtaattcaaa tggaaatctg atttgatgat gcttctgctg ttgaaataaa
     7741 gcagcatcta gcacctgaaa acaaactaat agtaacattc gaagatggag taggtccgta
     7801 ttttcagcat gcaataatcc atatgtaagt tcaattcacc cttgaaatca tcggaccaga
     7861 taaagttatg accaatctat cccaagcaat ctagaagaga tattagtaaa gggacattta
     7921 ctagaagtct tagatgagcc tataaatata tgttctgatg gcgtcatcag tggtctgatt
     7981 gacggaagct taggtgtgat cgatctctct ggaccaaaca acgaaggaat caaggggaat
     8041 ccggcacgtt aagaaaaaaa tagcataaaa aactagacac ttgatgagcg ttcattcaat
     8101 tgtttgaagg gactaggctg gtgtcatttt ttatacatat attttctctt tcgtcttgat
     8161 agggcttatg ggataatata aggaagaaaa tcatcgtttt attcaaaaag gagtttttga
     8221 caaatgaaaa aacgtatatt atttatcggt gatagcatta cagacgcagg aagagaccga
     8281 gcagaagcaa ctgatctagg taaaggttat ccacttttga ttgccggaaa actaatctcc
     8341 caatatccaa cgatggaatt tgaatgcatg aaccgtggga taggaggaga caaaattgca
     8401 gatctgcaag tacgctggca agaagattgt ttagctttac aacctgacta tgtatcgatt
     8461 ttgatcggaa tcaatgatac ctggcataat actagcgatc aggctatatt cggaactgag
     8521 aaatctgctc agcaatttga atccgtttat cgaaaattac taaatgaact tcaaacagtg
     8581 ggaatctgca acatcatctt gatggagccg tttgtacttc ctataaccga cgaccgtcat
     8641 ggctggcgta aagacttaga ccctaaaatc caaattgttc gtaaacttgc taaggaatat
     8701 ggcgcattgc tggttccttt agatggtata ttcaatgctt tagggattgt ttatggtttt
     8761 tcgaaatata caagagaaga tggggtccac ccaacgattg gcggacatga gatcattgca
     8821 caaagctgga tagatgcaat tgccgcagtc gattttttta gtggagataa aaatgagcga
     8881 aagaaaagtg agaaatgatg gaaatacggt gggcagtaaa agaagatcta cctcaaatca
     8941 atcagctgat tactgatcat ccagaatcat tcgtaaaagc aaaaacggca gctgacctaa
     9001 atgataagaa taaactattg ctcgttgctg taacaaaaga aaaacggatt atcggatttg
     9061 cgcaagcgga cgtgcaacag tcagaagaac gattggatca gcgaccatca ggaaaactaa
     9121 tccaacacac attagtaaca aaagaaaata cggaagaaat ccaaaaaaaa tttgcagaat
     9181 atttgatact ggaagctaaa aaaagaagaa taaaatcatt ttttgcccag ttttaatcaa
     9241 aaacagtaat agaaggagaa atacaatgag ttgtttagga aatgtcatct ggtttatatt
     9301 cggcggacta atcggtggtc ttagctggtt agcagcgggg atactttggt gtatcacgat
     9361 cataggtatc ccaatcggta tgcaatgttt taagatcgcc tccctttctt ttgcgccttt
     9421 tggcaaagaa gtaatttatc accagtctgg catgtcattg attgttaata tcatctggct
     9481 gatcgtttca ggcctaccaa ttgctctcgc acatgtcgtc agcggcatcc ttctatgtat
     9541 cacgatcata gggatacctt ttgccaagca atctttcaaa cttgctcgat tggcgttgat
     9601 gccattcggt gcagaaattg tataaaagag aataataaag gttagataaa gcatagagtc
     9661 aggtgggata catgtatttc acctgactct atgcgttctc ctgtataagt tcttccatgt
     9721 gacttttacg tcttttattt atatggggtt actgtttatg gaaagttgaa ataattttca
     9781 ttaaagaact ctttctatat ttttgaaagc gtagtggagc ttcgaatatc tgggaaggac
     9841 attttgcagg gattgaaaaa agatattgtc ctatcgaaaa attaatgaat ttagacaaat
     9901 tgccagcaac aggcttcaaa cttagttgct atcctgtcaa gatcaagaag gcaagtgcgg
     9961 gttggataag agcagtggca atgatcgaaa agaaaaagaa agaataagcc aaaacatctg
    10021 tatggaagaa attttccgat gcagatgttt ttcatttttt ctttcggata ccttgacata
    10081 tgaataaccg ttcatttata attagttatg aagagatatt catatgttga ggcgaggagg
    10141 tcattaaaat gaaaagttac agattagaag gtttagattg tgcgaactgt gcaatgaaaa
    10201 tcgaaaaagg agttcagaag atcaatggag tcaaggaagc aacggtaaac ttcacttctg
    10261 gaaaactaac gattgacgca gaggaagatc atttggctac gattgaacaa gaaataaaaa
    10321 aagtagtgaa ggaattagaa ccagatgtca aagtaacaga aatagataag gaaaaagtat
    10381 ctgaacatgg aaatgaaaaa gagagaaata cgctgttccg gattttattt tcccttgcag
    10441 gtatcgcttt attgctatta tttgatttta atgaaccaat tcgcttgata gggtatttat
    10501 tgatttatct gctgatagga tatgatgtag tgaagaaggc agtgatgaat atcgtcaaag
    10561 gaaaaatctt tgatgagaat tttcttatgt ctgttgctac gattggcgct atgttgatcg
    10621 gtgaatatcc agaagccgta gcagtgatgc tattttatca aatcggcgag tatttccaag
    10681 gattggcagt cagtcattca agaaaatcga ttcgcgaatt gatggcgatc cgtccagaaa
    10741 cagctcacgt gcagacgacg gaaggattga tgaccgtgaa ccctgaagac gtgcagatcg
    10801 gtcagtttgt acttgtgaag cctggtgaac gtgtaccgtt agatggaacg atcatcgaag
    10861 gagaatcatt agtcgatacg tcagcactta caggagaatc agtccctaaa tctgtatatg
    10921 ttggtgaaac agtattaagt ggatttatca ataaaaataa accattttta gttcaagtag
    10981 aaaaatctta tgaaaattct actatcagca aattattaga attagtagaa aatgccagca
    11041 gtaaaaaagc accagctgaa aatttcatta ctaaattcgc gcgctattac acaccagtcg
    11101 ttgtaggatt ggccgtttta ttagctgttt tacctccact tgttgtttct ggagcggcgt
    11161 tttctgaatg gatctatcga gcattgacat ttttagtgat ctcatgtcca tgtgcattag
    11221 tgatctccgt accccttagt ttctttggcg gtatcggagg agcaagtaaa atcggtgtat
    11281 tagtaaaagg ttcaaattac ttggagttgc ttgcacaaac tgagacagtg gtattcgata
    11341 aaaccggcac attaacgaaa ggtgactttt cgatccagac gatcgataca aaaatcgatc
    11401 caaagatatt catgcaatat gttgcgagtg cagaacagtt ttctacacat ccgattgctc
    11461 aatctgtttt agaaggctac gcaggtccgc ttttaccaac agctaatatc caagaatttg
    11521 caggtgaagg gatcttagct gaagttgatg gcaaacaagt attagcaggt aatcacaaat
    11581 tgatggaaag atttgaaatc tcttttcctt caagtcaaga aatcggtaca ttgctttatc
    11641 tagcgatcga tcaaagttac agtggttatc ttgttattgc agataccttg aaagaagatg
    11701 ccgtagacgc attggttcaa ttaaaaaagg ctggtgtgaa gaacacagtc atgttgacgg
    11761 gcgattcgaa aaaaattgct gatcatatcg ggaagcaagt aggcgtggac aagatatata
    11821 gcgaattgct tccagaagat aaagtgcagc ggttagagga aatcttacaa agaaacaata
    11881 aaaagaccgc atttgtcgga gatggaatca acgatgcacc ggtgctagca agagcagatg
    11941 taggaatcgc aatgggtgga ttgggaagcg atgctgcaat tgaagcagca gatgtagtca
    12001 tcatgaatga tcaaccatcg aagattgcag aagcaatcca tttagcaaag aaaacattga
    12061 aaatcgtcaa acagaacatt gtctttgcta ttgggataaa aattttggta cttgccttag
    12121 gtgcttttgg ttttgcatca atgggagatg cagtatttgc agatgttggg gtgacagtat
    12181 tagctgtttt gaatgccatg cgaagcttgc atgtaaaaaa taaacgttga tcaatgaaga
    12241 ggacgaatga acgtcctctt ttttttatat ccttttctta atgaaaaatg taaagaaaat
    12301 agataggatt ataaaataac taatgttttt aattttgcag aaaattcaaa atagcttgaa
    12361 attcaataag gtaaatgaaa taaaagaaaa taacttattt ttttgatgga aaaaatatga
    12421 aaaaacgatg tgtattaaat aaaagaatac acacataaaa taacactgtc ttgtaagttt
    12481 gttaaaaatt gaatatgatt acatctggat aacaaatttt tatcataaag gagagaacga
    12541 atgaacaaca aacaattacg ctggtttact gttgcgttaa ttgcatttaa catggtttgg
    12601 ggcatgggga atgtagttaa taactatgct cagcaaggag tatcagttgt cacctcttgg
    12661 ctattgattt tggccattta ttttattcca tacgcattga tcgttggaca attagggtca
    12721 gccttcaagg atagtaaagg aggcgtcagt tcatgggtcg aaaatacgac atctaataaa
    12781 cgactggcat actatgccgc ttggacttac tgggtcgtcc atattcctta tttggcacaa
    12841 aagcctcaag caatcctgat tgctggcggt tgggcagtcc aaggaaatgg aaatatcgta
    12901 aatacgatgt cagtacaaat ggtagcagtt atttcactta ttatatttct tgccttttta
    12961 tatttatcaa caaaaggact ttctactttg aaagtgattg gcggactggc cggaacagcg
    13021 atgttcgtca tgtcgatctt atttattctt ttagctgtaa cggcaccgtt catcaatcca
    13081 acgatggaat ttgccacacc acatatgaat caagtgaaaa catatattcc aacatttgat
    13141 ttcagttatt tcacaaccgt ttcgatgcta gtatttgcag ttggaggagc ggaaaaaata
    13201 tccccttatg tcaactctac aagaaatcct gcaaaggaat ttcctaaagg gatgatcttc
    13261 ttagcagcaa tggtagggat ttgtgctgta ttaggctcag tcgcaatggg tatgctgttt
    13321 gctagcgata atattcctaa agacttgatg gcaaatgggg catacagtgc ttttcaaatt
    13381 ttaggtaatt actatggtat cggtaactca ttgatgatca tttacgcatt gacaaacatg
    13441 attggacaaa tctccgcatt agccttttca attgatgcac cactaaaaat cttgttagca
    13501 gatgcggatc cagaatttgt accaaactgg ctacgtaaac gtaatcgtaa aggtacattg
    13561 gtgaatggtt atcttctgac aggtatacta gtaggaatca ttattttgtt gccgatcttt
    13621 ggtatcaaag atatgaatga attagtaaaa tggttgacga acttgaactc agttgtcatg
    13681 ccaatgcgtt acctatgggt gttcttggca tatatgatgt tgaataaagc ttataagaaa
    13741 ttcaattctg aatataaatt tgttaaaaat ccaaaaatcg gttttatctt tggtgcttgg
    13801 tgctttgcct tcactgcgtt tgcatgtatc ctaggaatgg tgccaaaagt agattatact
    13861 gctgatccta aagcatggtg gttccaatta ttcacgaata tcatcacacc aattgtcttg
    13921 atcttattag gtatgatctt gccagcaatt gctcgtcgag acaaaaacaa agaaatcact
    13981 gaaccagaaa cagtggttca gccttaaaat agaaatactt gttacaagag gttgtgacag
    14041 aagtggtcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttctca aatttttgtg
    14101 aagtttcggc ttgtttttcg cagaagctac ttctggaaca ccgtgaatca gaggttgtga
    14161 aaaagctgtc ctgcatcaag taataagaac agccaaacaa aaatagcccc tcatattttt
    14221 cgttttgctg ggcttattac cgcagatgca agcttttgaa caccgtttaa gaaagaggta
    14281 gtgagcctgc cgtttaactc cgagtcacaa ggagcaattt caaaaaacaa cttctcatgt
    14341 ttgttgacta ttgtgccttg tgaccgaggt gttggcagga gaacaccgtt taaggaagag
    14401 gttgtaaaat cagcgatttg acctgagtat tagaggaaca aacgaaaaaa tagctcctca
    14461 tattttgccg ttttttgagt taatgctgaa ggtcagctga ttgaacacca tttattcgaa
    14521 acaagggact ttgacacgac ttttgtcaca gtcccttgtt tttttgcggc gttataagtg
    14581 gtatgatcga accaaattcc aaagagaagt gagggagaag aatgaagatc atcgtgattg
    14641 gacaaagtgg gtcgggaaaa tcgaccctcg caaggaagat caaagaaatc accgactttc
    14701 cgctactgcc gctagacctt ttatggcata caacagacta cagtattcag gcaaaaaagt
    14761 ggtttttgca agaacagcaa tcgtttatgg tatctaatcc gtcatggatt gttgaaggaa
    14821 attatacttc tacattagag gaaaggatta aagaagcaga taagatcatt tggcttaaag
    14881 tgccgcgtta tctcgccatc taccgagtag tttggcgttc tctaaaaaga aagataaaca
    14941 aaaaatctcg gccagatatg cctgaatcat tttcagagaa actaaacagg gaatacttag
    15001 aatttttatc ttttatctgg cattttgaag aaaacaatga accgaaaata cagcagctga
    15061 tccaagtagc taatgcaaga aataaactga tcatccttaa aacaagacga gagaaacaag
    15121 aatttttaac taaattgaaa atagagagca aaaataattg acagtttttg tttacaagcg
    15181 taatctgtat tcataagcta atgattacat ttgtaaacga aaggtgtgaa ataaatggaa
    15241 aaagtcaaaa cgccagtaaa gatcagtgat tcagagtggg agatcatgcg tgttatttgg
    15301 acacttggac agacgacagc ccaagaaatc acgcagatct tagctgattc gatggattgg
    15361 aaaccagcaa cgatcaaaac tttgctggga cgtttggtaa aaaaagaagt gatctggaca
    15421 gaacaagaag gaaaaaaatt catttatcat ccagctgtct cggagatgga aacagttcgc
    15481 agtgcgacgg aaaatctttt ttcccatatc tgtgcaaaaa ggattggaga gacgattgcg
    15541 gatctagtag aagaagccac tttgactcaa gaagatatca atgagatttt gaaacaactg
    15601 gaacaaaagc aaccagtaga tacgatcgaa tgtaactgta tcccaggtca atgtgaatgt
    15661 aaacaacatc aataggagga agaaaaaatg aaacaacaat tttcaatcga aggtatgagc
    15721 tgcaatcatt gtgcagcaag agtagaagaa acagtaagcg cacttgacgg cgtgcaaaaa
    15781 gtgaaagtaa atttgaaaaa agcaaacggt acggtcaagt ttgatgaaac aaaagttcaa
    15841 tccgaaaaga tttgtcaagc aatcaatgga ttgggttata aagcagaggt gatttgatgg
    15901 caacagcaga aaccaaaatg gatacgttcg tcattacagg tatgacttgt gcaaattgtt
    15961 ctgctaggat cgaaaaagag ctgaacggac aacctggtgt ggtcaatgcc acagtcaact
    16021 tggccactga aaaagcaagt gtcaaatatg aagggacgac cactgaaaaa ttaatccaaa
    16081 gcgtagaaaa catcggttat ggtgcaattt tgtacgatga agcccacaaa caaaaaattg
    16141 cagaagaaaa gcaagcgtat ttgaaaaaaa tgctattcga tcttatattg agtacggttt
    16201 tgactttgcc gttgatgttg tcaatgattg ctatgatgtt aggaagccat gcggcgattg
    16261 ttcacttttt tcattttcca atcgtccagt tagtgctgtc tgctcctgtc caattttatg
    16321 tcggtgctcg tttttataaa ggtgcgtacc atgcaatcaa gacgaaagca ccaaatatgg
    16381 atgtattggt agcaattgga acatcggctg cctttgcatt gagcatttac aacggatttt
    16441 tccgtggaca cccccaagat ctttattttg aaagcagcag tatgatcatc acgctgattt
    16501 tgctcggcaa atatttggaa catacagcaa aaacgaaaac aggtaatgca atcaaacaat
    16561 tgatgtctct tcaaacaaaa accgcccaag tgataagaaa cgggaaagaa gaaacgttag
    16621 cgattgaaga agtagtcgtt ggtgatcaac tagtcatccg tcctggtgag cagattccag
    16681 cagatggtcg aattatttca ggaagcagtg cgatagatga aagtatgctt actggtgaaa
    16741 atcttcctgt agaaaagaat ccggatgaca cgctttttgg cgggacaatc aatacgaatg
    16801 gtctgctaca catggaagtc acacaagtcg gcaagcagac agtattagcg caaatcattc
    16861 aaatggtgga agatgctcaa gggagcaaag ccccaatcca aaaaatcgca gatcggatct
    16921 cagggatttt tgttccgatc gtattagtca tcgcgtttat cacgctcata gctacaggtt
    16981 tgatcactgg tgattggcaa ctcgcattga tccatagtgt ctctgtatta gtcattgcgt
    17041 gtccatgtgc attaggttta gcgaccccaa cagctattat ggtaggaacg ggtgttggtg
    17101 cacgaaatgg aattttaatt aaaggcggag aagcattaga agcagctgct cacttagaca
    17161 gcattgtttt ggataaaact ggaacgatta cagaaggaaa gcccaaagtt acagatctag
    17221 tcggttcaaa agaagtccta tctatttttt atactttaga acaagcttct gaacatccac
    17281 taggtaaagc aatcgtggaa tacggaaaac tgcaagaagc agcaacatac gatatgattg
    17341 attttacagc ccacccaggt gctgggatca gcggtacgat taatggagta cgctattttg
    17401 cgggtacacg taaacgatta attgaattga acctatcatt tgatgaatac caagaacacg
    17461 cgttagaatt agaacagcag ggaaaaacag tcatgttttt agctgatgaa aagcaagtga
    17521 tcgggtggat tgccgtggct gatcaaatca aactagaagc caaacaagca atcaagcagc
    17581 tccagaataa aggattagat gtttttatgc tgacaggaga caacaaactg gcagccgaaa
    17641 cgattggtaa acaagttggt attgatccaa agcatatctt tgctgaagta cttccagagg
    17701 ataaagcagc ctacgtagaa aaacttcaga aagatggcaa aaaagtcggt atggcaggcg
    17761 atggaatcaa tgatgcaccg gccttagcat tagctgatgt cggtatggca atgggaagtg
    17821 gaacggacat tgcgatggaa acagccgatg tgacgctgat gaatagcagt ttggcatcca
    17881 ttgcacaaac aatcgagttg tctaggttga cattgagaaa aatcaaacaa aatcttttct
    17941 gggcttttgt ctataatacg attggtattc cttttgccgc actaggcttt ttgaatccaa
    18001 tcattgcagg aggagcgatg gcgtttagtt ccgtcagtgt attgttgaac tccctgagct
    18061 taaatcgaca catgaaaaag taagagaagg gatggagtaa aaatgaatgg gaacgatatg
    18121 gagaaaaaac atgagcataa aaaagaagta gtaaacaaag aaagtacaga atctcatgaa
    18181 aaacagatgg agatgaaaca tgaccatagt cagatggatc attccatgca catgggacat
    18241 aaccatggag atatagcaaa cagcaaacaa atggaccatt cgatgcacat ggatcacgaa
    18301 cacggcggca tggatcattc catgcacatg gggaatttca aacaaaaatt ttggctatcg
    18361 cttatcctag ctatcccaat cattcttttt tcaccaatga tgggaatgga atttccattt
    18421 caagtaacgt ttcctggttc tgattggctc gtattgatct tagcaactat actatttatc
    18481 tatggcggtc agccattttt aagtggagct aagatggaat tgaaacaaaa aagtcctgct
    18541 atgatgacac tgatcgcgat ggggattaca gttgcatata tttatagtgt ctattcgttt
    18601 atcgcaaatc tgctcaatcc acatacacac gtcatggatt tcttctggga attggctact
    18661 ttgatcgtta ttatgctact aggtcactgg attgaaatga atgctgtgtc gaatgccagc
    18721 aatgctttac aaaaactagc agaattactg ccagaatcag tgaaacgctt gacgaaagat
    18781 ggaaaagaag agacagtttc attgaaagaa gtaaacgaag gtgatcgttt gatcgtccgg
    18841 tctggtgata aaatgccaac agatggtgta atcttgaaag gtgaaacaat tgttgacgaa
    18901 tcagctgtga ctggcgaatc aagaggaatc aaaaaacaag ccaatgacaa agtgattggc
    18961 ggttctatca atggggatgg aacgatcgaa atcgaagtaa ctggaactgg tgaaaatggt
    19021 tatctagcga aggttatgga aatggtgcga aaagcacaag gagaaaaatc caagctagag
    19081 tcattatctg acaaagtggc aaaatggctg ttttatgtcg cattaattgt gggtatcctg
    19141 gcattcatcg cctggttgtt cttgacagat cttcctaatg cattagaacg tatggtaaca
    19201 gtctttatca tcgcctgtcc tcatgctcta ggtttagcta tcccattagt tgttgctcgc
    19261 tccacatcaa tagcagctaa aaacggatta cttttgaaaa accgcaatgc actggagcaa
    19321 gccaatgatc tagatgtgat catgctggac aaaacaggaa cactaacaga aggaaaattt
    19381 actgtaacgg gtgtcgaagt acttgatgat gcgttcaata aaaatgaaat ccttcaatat
    19441 ctaggagcct tggaagcgaa tgccaatcat ccattggctg ttggcattat gaattatttg
    19501 aaagaacatg aaatcaagcc ttatcaagct gaaaatctaa aaaatctttc aggagtcggg
    19561 ctagaggcaa cagtcaaaaa acaacaagtg aaaatagtta atgaaaaaga agttgagcgt
    19621 ctcggattaa acgtagaaca agcattattg aaaccttacc aagaacaagg aaataccatc
    19681 agcttcctga ttttagaaaa tcatctagct gcaatcgttg ctttaggtga cgtagtaaaa
    19741 acagaagcaa aagaatttat ccgaacattg aaagaaagaa aaatcactcc tgtcatgctt
    19801 actggtgaca ataaaaacgc tgcccaagca gtagcagatt atttagggat cgaagaatat
    19861 tatggcggtt tattaccaga tgataaagaa gctgttgtcc agaaatacct tgaccaaggg
    19921 aaaaaagtaa tcatggtggg tgatgggatc aatgatgcgc caagtttagc ccgtgcttca
    19981 atcgggatgg caatcggtgc agggacagat atcgcaatcg attctgcgga tgtcgtattg
    20041 acaaacagcg atccaaaaga tattttgcat tttcttgatc tagccaagca aacgcgaaag
    20101 aaaatgatcc agaacctctg gtggggggca ggttacaata ttcttgcaat tccgctagca
    20161 gccggaattc ttgcgccaat tggtatcata ttaagtccag cagttggtgc tgtcttgatg
    20221 tcgttaagta cggtagttgt agctctaaat gctttgacat tgaaaatcaa ataataatga
    20281 aaaaa
//
LOCUS       DAIGWC010000052        20252 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.053, whole genome shotgun sequence.
ACCESSION   DAIGWC010000052 DAIGWC010000000
VERSION     DAIGWC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.053"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            225..1082
                     /locus_tag="NOB74_001922"
     CDS             225..1082
                     /locus_tag="NOB74_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HCI1221094.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1197..2117
                     /gene="pstC"
                     /locus_tag="NOB74_001923"
     CDS             1197..2117
                     /gene="pstC"
                     /locus_tag="NOB74_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HCI1221095.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2117..3001
                     /gene="pstA"
                     /locus_tag="NOB74_001924"
     CDS             2117..3001
                     /gene="pstA"
                     /locus_tag="NOB74_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HCI1221096.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            3016..3822
                     /gene="pstB"
                     /locus_tag="NOB74_001925"
     CDS             3016..3822
                     /gene="pstB"
                     /locus_tag="NOB74_001925"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCI1221097.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3838..4596
                     /locus_tag="NOB74_001926"
     CDS             3838..4596
                     /locus_tag="NOB74_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCI1221098.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4609..5286
                     /gene="phoU"
                     /locus_tag="NOB74_001927"
     CDS             4609..5286
                     /gene="phoU"
                     /locus_tag="NOB74_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HCI1221099.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5524..6554
                     /locus_tag="NOB74_001928"
                     /pseudo
     CDS             5524..6554
                     /locus_tag="NOB74_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
     gene            6551..7318
                     /locus_tag="NOB74_001929"
     CDS             6551..7318
                     /locus_tag="NOB74_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCI1221100.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7418..8986
                     /gene="liaX"
                     /locus_tag="NOB74_001930"
     CDS             7418..8986
                     /gene="liaX"
                     /locus_tag="NOB74_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HCI1221101.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9283..9603
                     /locus_tag="NOB74_001931"
     CDS             9283..9603
                     /locus_tag="NOB74_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HCI1221102.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9603..9953
                     /locus_tag="NOB74_001932"
     CDS             9603..9953
                     /locus_tag="NOB74_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCI1221103.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10120..11058
                     /locus_tag="NOB74_001933"
     CDS             10120..11058
                     /locus_tag="NOB74_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HCI1221104.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            11073..11903
                     /locus_tag="NOB74_001934"
     CDS             11073..11903
                     /locus_tag="NOB74_001934"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCI1221105.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKLHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11947..12972
                     /locus_tag="NOB74_001935"
     CDS             11947..12972
                     /locus_tag="NOB74_001935"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCI1221106.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12987..13925
                     /gene="galU"
                     /locus_tag="NOB74_001936"
     CDS             12987..13925
                     /gene="galU"
                     /locus_tag="NOB74_001936"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCI1221107.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            14050..14490
                     /locus_tag="NOB74_001937"
     CDS             14050..14490
                     /locus_tag="NOB74_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HCI1221108.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKATAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14493..15095
                     /locus_tag="NOB74_001938"
     CDS             14493..15095
                     /locus_tag="NOB74_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCI1221109.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15154..16260)
                     /locus_tag="NOB74_001939"
     CDS             complement(15154..16260)
                     /locus_tag="NOB74_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCI1221110.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16470..17471
                     /gene="ccpA"
                     /locus_tag="NOB74_001940"
     CDS             16470..17471
                     /gene="ccpA"
                     /locus_tag="NOB74_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HCI1221111.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17807..20152)
                     /locus_tag="NOB74_001941"
     CDS             complement(17807..20152)
                     /locus_tag="NOB74_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCI1221112.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
BASE COUNT         6441 a         3576 c         4307 g         5928 t
ORIGIN      
        1 ttaactttgg ggtatctctt gttttttggg gaaagcaaga aataagctaa tatatgctat
       61 taaaagagac acatttcaaa gccagtatag catagaaact tttaatgaga tagttttttt
      121 tacaattatg agaatttatt ttgttattta atgattttga ttcgttttca tcaagtaatg
      181 aaaatgataa aataaacata ctttaggatt aaaggagatt tctaatgaaa aaacttaaat
      241 tattcttacc aataatagga ttagccattc ttttatcagg ctgttcaaag tggattgatc
      301 gaggagaatc cattacggct gttggctctt ctgctttaca gcctttagta gaaacagttg
      361 ctgaaactta ccagacagaa aatcctggaa aattcatcaa tgtacaaggg ggcggaagcg
      421 gaactggttt gtctcaagta cagtcaggag cagtcgacat cggaaactct gatttgtttg
      481 cggaagaaaa atcggggatc gatgcctcag cattagtcga tcatcgagta gcagttgttg
      541 ggatcactcc tattgtgaac aaggatattg gcgtaaaaga catcagtatg gaaaacctga
      601 aaaaactatt tacaggcgag atcaaaaact ggagtgaagt cggtggaaaa gatcagccag
      661 tagttatatt gaaccgcgct tcaggaagcg gaacccgtag cacgtttgaa aaatgggtat
      721 tggacggaga aacagctgtt caggcacaag aacaagattc aagcggaatg gtgcgccaga
      781 tcgttgccga cacacccggt gcaatcagct atgttgcttt ttcttatgtt tccgatgatg
      841 tagatacgtt gaatgttaac ggtgtagaac cgacagatga aaatgtgaca acgaacaaat
      901 ggacgatttg ggcatatgag catatgtaca caagagatca tccaaaaaaa ctgacaaaag
      961 aatttttaga ctatatctta tctgatgaag tacaagataa catcgttgga gaactaggtt
     1021 atatccctgt ttctcatatg aaagtcgaac gtgattggca aggaaatatc gttaaagagt
     1081 aatctttaca caaaatttac aaacttagct aaacttttac atgttattaa aaccaaattg
     1141 atgttcaatt tgtacactga gtgagtatgt taaacctgat taagggggag tcatctgtgg
     1201 aagatgtgaa aaaagtatta ttaacaaaat caaaacgttc aaaaatggaa cagcgtggaa
     1261 aattcatcag ttttttatgt atcgcgctga tcgtgttggt tgtattatct attttttatt
     1321 ttgtagctag taaaggattg gccacctttt ttactgataa gatcaatgta tttgattttc
     1381 tgtttggtac agattggaat ccaagccaaa tcggagcaaa tgggaaacca atggtagggg
     1441 cattgcctat gatcacaggt tcgtttattg tgaccttttt atctgctatc gttgccacgc
     1501 catttgccat tggtgcagca gtattcatga cggagatctc tcctaaaaac ggaacgaaga
     1561 tcttacagcc ggtcatcgag ctgcttgtag gtattccttc tgtcgtttat ggttttatcg
     1621 gtttatcagt tatcgtgcct tttgtcagaa gtatttttgg cgggacaggg tttggtatct
     1681 tagctggtac atttgtgttg ttcgttatga tcttgccgac tgtcacaacg atgactgttg
     1741 atgcattaaa ggcagtgcca cggcactatc gggaagcttc attagcgctt ggtgccacaa
     1801 gatggcaaac aatctacaaa gtcgtgctac gagcagccgt gcccgggatt ttaacagcag
     1861 tcgtttttgg tatggctcgt gcgtttggtg aagccttagc tatccaaatg gtcatcggta
     1921 atgcagcatt gatgccaaca ggacttacta ctcctgcttc tacattgacg tccatcttaa
     1981 caatgggaat cggaaataca atcatgggaa cagttgaaaa taatgtgtta tggtcattag
     2041 cgctgatctt gctattgatg tcattattct ttaatatcgt gatccgtatg attgggaaga
     2101 aaggagagct gaaataatga acgcaaaacg ctcagataaa attgctacag gtgttttata
     2161 tatagtttcg gggatcatcg tattgatttt agcagcttta ctactttata tcttagttcg
     2221 gggaataccg catatttcat ggtccttctt gaccgaacct tccaaagcct accaagaagg
     2281 cggtggaatc gggatccagc tatttaactc gatttatttg cttttgatca cgatgatcat
     2341 cagttttcct atttctttag gtgcgggtat ctatctttca gaatatgctg gaaaaaactg
     2401 gctaacagat gtgattcgca cgtcgattga aatcttgagc tcgttgcctt ctgtcgttgt
     2461 cggtttattc ggtttcttgg ttttcgttat tcaattccag tatggtttct cgattatttc
     2521 tggtgcattg gctttgactg tattcaactt gcctcttttg actagaacag ttgaggagtc
     2581 tttacaagcg gtccattaca cacaacgaga agcaggattg gccttaggtt tgtcacgctg
     2641 ggaaacagtg ataaaagtgg tggttccaga agcgacacca gggattttga ctggtgtgat
     2701 cctaagttct ggaagaattt ttggtgaagc agctgcattg atctatacgg ctggacaaag
     2761 tgcacctgcg ttagatttta cgaactggaa tccattaagt gtttcaagcc cgatcagcat
     2821 tttccgtcaa gctgaaacat tagctgtcca tatttggaag atcaatacag aaggcacgat
     2881 gcctgatggt gtttctgttt cggctggcgc ttctgccgtg ttgatcattg ctgttttact
     2941 gttcaacttc ggcgctcgtg cgattggcaa acgattatac cgaaaaatga cttcagccta
     3001 aggagaagaa gcaaaatgaa aaaatataac tggaatgaaa caaatgtcat caccatgcca
     3061 aaagagaaag aagtagcact atatacggat gatctacatg tctggtatgg cgacaatgaa
     3121 gcaatcaaag gagtggatct ggaatttgaa aaaaataaga tcactgcact gattggtcct
     3181 tccggctgcg gaaaatctac gtatcttcgt tcgttgaatc gaatgaatga tgggatcgct
     3241 aatacgaaaa tcactgggaa aatcatgtat caaggcgtag atattaatgc gcctcaagtg
     3301 gatgtttatg agatgcgcaa acggattggc atggtttttc aacgtcctaa tccgttcagc
     3361 aagtcgattt atgacaatat tacatttgct ttgaaacagc acggcgaaaa aaacaaaaag
     3421 aaattagatg aaatcgttga aacaagcttg aaacaagctg ccttgtggga ccaagtaaaa
     3481 gacagcttgg acaaaagtgc cttggcttta tctggcgggc aacagcaacg tttatgtatt
     3541 gctcgtgcga tcgcgatgaa acctgatatc ttgctgctag acgagccggc aagtgctttg
     3601 gaccctattt cgacaggaac ggttgaagaa acacttgtaa acttgaaaga agactatacg
     3661 atcatcatcg tgacgcataa catgcaacaa gcagctcgta tcagcgacta tactgccttt
     3721 ttctatctag gaaaagtaat ggaatatgac aaaactaaca agatatttac cagaccaaaa
     3781 attcaggcaa ccgaagatta tgtgtccggt cattttggtt aagacggagg cctcaacatg
     3841 acaaaagaaa ttatttcatc taaagatctt catctgtatt atggaaagaa agaagcacta
     3901 aaagggatca atctaagttt caatcaaggg gaaatcactg cgatgatcgg tccttctggt
     3961 tgcgggaaat ccacttatct gcgttctttg aaccggatga atgacctgat tccgaatgta
     4021 acgatcaccg gaagtgtttt atataaagac aaagacatct atggtccaaa aacagatgtt
     4081 gttgaactaa gaaaagaaat cggcatggta ttccagcagc caaacccatt tcctttttct
     4141 atctatgaaa atgtcatcta tggattgaaa ttaaaagggg aaaaagataa aaaagtcctt
     4201 gatcaagtag ttgaagaaag cctgaaggca gcgtctgttt gggatgatgt gaaagacaaa
     4261 ttgcataaaa gtgctttatc tttatccggt gggcagcagc agcgtgtatg tatcgcacgt
     4321 gttttggcag ttaatccgga aatcatctta ttggatgaac caacaagtgc gcttgatcct
     4381 gtttctactg ggaaaatcga aagtatgctg ttagaattaa gagagcggta tacgatgatc
     4441 atcgtgaccc ataatatgtc tcaagcttca cgtatttcag ataagacggc attcttttta
     4501 gatggtcact tgatcgaata caacgatacg aagaagatat tcatgaatcc agaaaaacaa
     4561 gagacagaag attatatttc aggtcgattt ggataaggag gaaacggaat gctacgtaca
     4621 caatttgaag aagaattgct gaatctccat aatcagttct acgaaatggg gatgatggtg
     4681 agcagcgccg tgcacaagtc agttcgtgca tacatcaaac acgataaaat cttagcccaa
     4741 gaagttatcg aaaacgatat aaatatcaat aacatggaaa cacgcttgga aaagaaaagt
     4801 tttgaaatga tcgcattgca acagccagtt acaactgatt tgcgtatgat cattacggtc
     4861 atgaaagcta gctcggattt agaacgtatg gccgatcatg cggtgtctgt tgctaaatcc
     4921 acgattcgcg taaaagggca gacgagaata ccggaaatcg aaaaagagat ctccgatatg
     4981 tccgattatg tgaaaaaaat ggtggacaac gtcctagtag cttatgtcaa aacagacgaa
     5041 aaagacgcac gtacgatcgc caatatggat caaagagtca atgactattt caatcgaatc
     5101 tataatgcaa caatcaaaaa tatgcaggaa aatcctgaga cagtcatcag tggaacagac
     5161 tacttgaatg ttgccagtta tctagaacgg atcggagact atgtgacaaa catctgtgaa
     5221 tggatcgtct acttggctac agggaaaatc actgagttaa atacgaacca caatgagatt
     5281 ttctaaactg aagctgtgat tatgccgttt gtttaggaaa agaggttgtg aaatcagcgg
     5341 ttgtgaaaaa gctgttctgc atcaagtaat aagaacagtc aaacaaaaaa tagctcctca
     5401 tatttttcgt ttggctggac ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     5461 ggaaagggtt tgtgacaaaa catgtcacaa acccttttca tcatttcata gaaaggataa
     5521 agaatgcaaa aaaaaattag catcatcact atatttttta tttgtgtgct tacttcatgg
     5581 gttattcagc atcaagctgc tttatatgaa gtacctgtca tcgagatcga aaaagtacga
     5641 ataaaagagg atcatcaatt gattacagga agactgatga acacggatca aaaaggagaa
     5701 tcgatttatt tatcggttcc ttatcaaaaa aatcaaatag aaacagcaaa tataaaagcg
     5761 agacaaatgt atctagtcca aatgcatgga gatgaatggc agctagtagc aaaaaaaaat
     5821 gatggctggc ttttcttctt cacaagtatc ttcattggcg ccatgttgct tattggcgga
     5881 aaacagggtc tatttgcttt aggaagtctc atcatcaata tcgttttact ttacttttgt
     5941 tgctcatctt tactaaaaca gaagggattt ctctattaaa tatatctatc ctgttcgtcg
     6001 ttatagggat gattattagc atattggctt taaatggatg gaatagaagc agtataatca
     6061 aaatttcagc tgcagttacg agtgtttttt tagcattttt tatttgtctt ttgacaatga
     6121 atcattggaa agaccaagga ctgcgctatg aggaactgaa ttatctgaca cgaccgtatc
     6181 gttctgtttt tctttctagc gtactgattg gaacagctgg aggaacactc gataccgtta
     6241 tcacagtcat tgcgacatta gaagaattga ctaagcgaca accagaaata acagcgaaac
     6301 agttatggct ttcaggaagg caagtgggtc gagatgtgat tggctcgatg accaatatcc
     6361 ttttgttcgt ctatatcagt gggtcagttc catcgcttct tttatattta ggaaatcaat
     6421 ggtcgttcaa agaaacgata gaacagcatt tatcattgga atttttacgc gtcattgctg
     6481 gcagcttagg aatagtatta tcgatcccta tctcggtcct cttttttctg actgccagga
     6541 ggctgaaacg atgaatgtac ttattatact tgttgggatt ttagcaatca gcgtgctact
     6601 tattggcggt acgcaaggta tgtatattct tttaggctta ttcatcaatt tagggatctt
     6661 tttcctgttg ttattcggtt atcatcagaa gtggccgata ctggcattgt cggtcatagg
     6721 atttttattg attgctgtgg ttatcttatt ttttatcaac ggttataatc taaaaatgcg
     6781 tgcagctttt gtgagtatac tgatcttttt attttgtttc ctactattgc ttcctatcac
     6841 tgatttttta gcgatccaag gttttacatc ggtagaacta gaagaattat ctggcttaga
     6901 taagacttta gcgattgatt ttagattact tacgagatcg ttgcttctga ttagtcttag
     6961 tggtgctgtt ttagatgcta gtgtagcaat ttctagtggg acattcgaag tatatcaggc
     7021 aaatccgcaa ttatcttttt accaattgcg ccattctagt ttcgctattg ctaaaaaaat
     7081 attggcgtca acagtaatga cacttctttt tgcattcatg ggaagttctt tagcgttgat
     7141 cctctggttt attgatttag acattccttt tcagcaagtg atcaatgaaa aatcatttgt
     7201 tctagaatat acgatggcta ttcttaccac attgtctgca ctacttgttc ttcctttaac
     7261 ctgcgtgact acagcatatc tctttacaaa aaagaaagaa caactcaaga tggagtaaaa
     7321 gttacaactt aagtcctatg acatttttac tgaatcagtg cataatatgg atgtaaggaa
     7381 aagcttgcaa acaattttgc ttaaggaggc aatttccatg aaagaaagag aacgtatttt
     7441 agatttagtg aaaaaaggaa tcctttcgac tgaagaaggc ttagatttat tagaaagcat
     7501 ggcaactgaa aaagacgaaa agcaaataaa aaaagaagca gacaaggtaa ctgctagtca
     7561 taaagaaaaa gatcaggcaa gtcaattgat cgataaactt gaaaacggcg aagaagaaat
     7621 ttctgagcca gttgatccaa aggaaagaga aagacaagat caagaaaact tagaaaagat
     7681 cttagatgaa ctagcaactg aagcgaataa aacttcggcg cgtctagatg aagtaaatgc
     7741 tcaattcgct gacaataagg cagcacgcaa tgagaaacag gaagcattga tgcagctgaa
     7801 tacaaaagaa gaattaggcg agttgacaga agaagaatta gcacagcgtc agacgttaga
     7861 agcagaaatc aaagaattag aagctagtgg cgatacactg ttagaagaac aattgaaatt
     7921 agaagcagaa ttaaaagata tccgtaagaa tcaatggtct gagaaaaaag aaacgtttac
     7981 tgataagttt gaattgccag atgattggaa agatcaagca acagatacac tgaatcaagt
     8041 aggcgaaaaa atgtcagaag ctggatcaca gttaggcaaa ttcttgaaga aaacattcca
     8101 aactgtttca gaaacagtga atgacaacat ggaatggaaa gatgtcagct tacgtgtccc
     8161 tgggattgcg acaacgaaat ttgagcatga attttactat gaagctcctg cagcaagtat
     8221 ccttgatatc aaggcagcaa acggaaacgt gacgttaaaa acgtgggaca gcaacgatgt
     8281 gaaagttgaa gctaagatca aactttacgg aaaaatgggt gctgaaccat ttgaagcatt
     8341 ctctgaacgg agccagattg aggttaatga agatcatatc tccttccaaa ttccaaataa
     8401 acgtgtgcgt gcagaccttg ttttctactt acctaaacga gtatacgacc acgcagctat
     8461 taaacttcta aatggcaaca tcatgattga aacattggaa gctaaagata tttatacaaa
     8521 atctacgaat ggtaacatca tcgtggacca attaactgca acgatgctgg aagtagaagg
     8581 tgtaaacggc aatatcgata ttcgaaacgg gaacatctta gattctatta tcgaaacagt
     8641 aaatggtaca gtgacatttg gtgcgacagc agaaaacctt tctgtgtctt tggtaaatgg
     8701 tgatgtacgt cttacgatta aagaagataa tttgaaaaaa gtagaagcaa gttcagtgaa
     8761 cggaaatgtc aaagtcgctt taccagatgg catcggtttg gaaggacatg ctaaaacaag
     8821 tcttggaagt atcaacagcc gtctgtccaa ttacgaagta gttcgtgaga aaaaagaacg
     8881 gacaaaccaa atgttgcaat tccgtcgtgt ttcagatggt gaaatcacgc aagtgcaact
     8941 ttcaacgaca acaggaagta tctatttaaa agatacagat aaataaagag gttgtgaaag
     9001 agatgttcag ccttgagcaa taagaagcga ttttgtaaaa tagcttcccc tattttacaa
     9061 aattgtgcct tattgccgat aggctatctc ttgaacaccg tttaccaaga gattatgaac
     9121 ctgccaatta tcgccgagtc acaaggaata atttcagaaa aagctcgtca cgttttatga
     9181 atatggtaat ttgtgaccga gaattttgca gaaagacacc gattaagaag aaggttgtca
     9241 caacgatttt cttcatttaa aatagtagaa cagaggtgag acatgatgaa aaaaaagttg
     9301 acaaaatcca ataaaaatgt tgttttgaca gggactttag caggaatagg agaatacatc
     9361 gggattgatc cgactgttat ccgtgtgctt tatgtattcc tgagcttagt tgcttttgga
     9421 agtccaatca ttttatacat tttattagct ttgattatcc catctgcgcg ttctgcacga
     9481 acaaactatg gacataacaa tgcatattat gaaaaaaaca attatcgtga acaaactcgt
     9541 gaacaaacaa aaaaacgcaa agaagcggaa aaaatcgatg atgacgaatg gagtgacttt
     9601 taatgtcgta ctttcaacgt attttagtta atacgttaac attcatatca ttggctgttc
     9661 tttttcctgc gatggtccat gtgagcagta tttggacggc cgttcttgcc agcttcgtat
     9721 tgtctgtgtt gaatatgttt gtcaaaccga ttttgacgat actgtccctg ccctttacat
     9781 tagtcacatt gggattgttt acgtttgtta tcaatgcagc gattcttaaa atgacctcct
     9841 tttttgtggg agcagaacat tttagttttt cttcattcgg tgcagcgttg ttagtagcta
     9901 tcttgatgtc gcttgtcaat gtaattgtca gcgaacataa cagtagaaaa taaaagaaag
     9961 ctgtgccgaa ctatcggcgc agttttttta tttagaatca ggaatgcgtt ttctattaca
    10021 ttggtaatta aataaaaacg ttttttttaa ttggtagtac ttttggctag acaatgataa
    10081 aatgatagag aacactctaa tagaaatgag gtagcatgaa tgtcagaagt tgtaaaagtt
    10141 agccaattag tgaaaaaatt atctttggaa atcgtgacag gcgacgagaa aagcttagac
    10201 cgtgtcatcg taactgggga catctcacgc ccaggactag agttgactgg ttattttaat
    10261 tattattccc ataatcgttt acagctattt ggcagtaaag aaatcagttt tgcggaacgg
    10321 atgatcccag aagagcgttt gatcatcatg agaagattat gtagtgaaga tatgcccgca
    10381 tttattattt caagaggatt accggctcca gaagaaatga tccaggcagc aaatgaaaat
    10441 gggatagctg tactgcgttc tcccatctca acttctcgtt tattaggaga attatccagt
    10501 tatttagatg gtcgccttgc ccctcgaaca agtgtccacg gtgttttagt ggatgtttac
    10561 ggattaggtg tactgattca aggtgacagt gggataggaa aaagtgaaac agcgttggag
    10621 ttgatcaaac gcggtcatcg attgatcgca gacgatcgag tagatgttta tcagcaagat
    10681 gaattaacgg tgatcggaga accgcctaaa atcctggaac atctaattga aatccgagga
    10741 atcgggatca ttgatgtaat gaatcttttt ggtgcgagtg cggtacgtgg ctctatgcaa
    10801 gtccagttgg ctgtttatct ggaagcatgg gcaaaagata agaaatacga ccgtctgggc
    10861 tctgaagaca cgaccgttga aatcgcggaa gtgggcattc cacaaataaa aatccctgtc
    10921 aaaacaggac gaaacgttgc aatcatcatt gaagtagccg cgatgaattt ccgtgcacgt
    10981 acaatgggct ttgacgcaac gaaaacattt gaagaaagat taagtcgctt gattgaagaa
    11041 aactcaggca acgactagca aggagtgaca atatgttagc acaaatcaat cgagttgctt
    11101 ttgagcttgt agggattcct atctactggt atgcattgat catcgtatca ggtatcatta
    11161 tcgccatgtg gcttagcagc agagaggctg ttcgggtagg attaaaagca gatgatgtga
    11221 cagattttat gttgtgggga ttgcctatct ccattattgg cgctcgctta tattatgttt
    11281 tatttgatct tccccagtat atagctgatc caatccaaat attcaatatc cgttcaggag
    11341 gcttagctat ttatggcgga ctgattgcag gcgcgatcac gctgtatttt tttactaaat
    11401 atcattttat ttctttgtgg acttttttag atatcgctgc accaagtgta ttattagcac
    11461 aggcaatcgg tcgttgggga aatttcatga accacgaagc atatggacca gacacgacgc
    11521 gaagcttctt agaaagtctg catttaccgc aattcatcat tgataatatg tatatcgaag
    11581 ggatctatcg tcaaccaaca tttctttatg aatcactttg gagtttgatt ggatttattt
    11641 tgcttttgtt tttacgaaag aaactacacc ttttgaaaaa aggcgaagtc cttttatgtt
    11701 atctaatgtg gtatagtttc gggcgtttct ttattgaagg attacgtaca gacagtcttt
    11761 actttttagg tgtgatccgt atttctcaat tattatctgc tgtgttattt gtcggtacat
    11821 tgattctatt tatttggcgc agaaaaaaag gaaatttacc ggattatgac cgctcattag
    11881 gaaaaaatca acaaattatc tgatttttag agcgttaaaa atgaaaaaaa tttcaggagt
    11941 ggtaaaatga attatagagt agcggtttta ggaccaggct cttggggtac tgctttggca
    12001 caagtcctcg ccgaaaacgg acatgacgtt cggatttggg gacatcgtgc ttcacaagta
    12061 gaagaaatca acacccaaca cacgaatcaa cgttatttac cagatcatta tctacccgat
    12121 tccatccaag cattcaccaa tatggaagat gcagtaaaag acgcagatgc ggtgctattc
    12181 gtcattccaa cgaaagcaat acgttctgtt gcaaaagaac tagtgcctaa attgaataca
    12241 aagccagtga tcatccatgc aagtaaagga ttagaacagg gaacacataa aaggatctct
    12301 gacatcttgt tagaggaaat cccagcagaa aaaagaaaag ctgttgttgt tctttctgga
    12361 ccaagccatg cagaagaagt agcgaaacat gacatcacta cgatcacagc tgcaagtaca
    12421 gatgcaaaag cagcaaaata tgtacaagag ctgttcatga ataattattt tcggatctat
    12481 accaatcctg atgtgatcgg tgtagagatg ggggcagctt tgaaaaatat tattgctatt
    12541 ggtgctggcg ctattcacgg cttagggttt ggcgataatg caaaggcagc aatcatgacg
    12601 cgcggattag ctgagatcag ccgtttaggt gtagcaatgg gtgccaaccc gctgaccttt
    12661 atcggattaa gcggagtagg cgatctagtc gttacttgca caagtgttca ttctaggaac
    12721 tggcgcgcag gcaacttgtt aggacaaggg cagcccctag aagaggtgct agccaatatg
    12781 ggaatggtcg ttgaaggtgt gaatactacc caagcagcga tggaactagc ccaaataatg
    12841 gaaatcgaaa tgcccatcac tcaaacaatc tatgaagtgc tgtatgaaca aaaagaaatc
    12901 aaaacagccg caaaagaaat catgttacgt gatgggaaaa aagaaaatga attctcatta
    12961 acaatttttt gaaggagcga atgtatatga aagtcaaaaa agcagttatt ccagcagcag
    13021 gattaggaac aagattttta ccagcaacaa aagctatggc aaaggaaatg ttgccaattg
    13081 ttgataaacc aacaatccag ttcatcgttg aagaagcgtt gaaatcagga atcgaagaca
    13141 tcttgatcgt tacaggaaaa gctaaacgac caatcgaaga tcactttgat tcaaatattg
    13201 aattagaaac aaacctaagt gaaaaaggaa agaccgaatt attgaaatta gtagaagaaa
    13261 cgacagatgt caacttgcat ttcatccgtc aatctcatcc aaagggttta ggacatgccg
    13321 ttcttcaagc aagagccttt attggaaatg aaccgtttgt cgttatgcta ggcgatgata
    13381 tcatggaaga tgaagtacca ttgacacagc aattaatcga tgattacgaa cgtactcatg
    13441 cttctacgat cgccgttatg caagttcctc atgatgaaac ttcaaaatac ggaattatca
    13501 atccaggaga agtattggaa gatgggttat acaatgtcaa aaactttgtt gaaaaaccag
    13561 atccaagcaa agcaccaagt gatttagcta ttattggacg ttacttattg actccagaaa
    13621 tttttgatgt attgtccgag caacaaccag gagccggaaa tgaaatccaa ctaactgacg
    13681 caatcgatac attgaataaa acacaacgcg tatttgcccg taaattcaca ggtaaacgtt
    13741 acgatgtcgg tgacaaattt ggttttatga aaacaagtat tgaatatggt ctaacacatc
    13801 cagaagtagg tgcaccttta cgtgagtata tcctgtcttt aggtaaaaca ttagaagcag
    13861 aaggaagcaa gatcgatcat aatccaaaag gaataacaga aatcaaagaa gaaaagaaaa
    13921 aataaccctt ttttctaacg agcttcagct gctaattgaa taaaaagtag ttgaagctcg
    13981 tttttatttg tttaaaaaac acgaaaatgc tatccttata gaaaagagag acaagaaggg
    14041 agtttgatca tgtcaggagg agaaattgca ggattgattg cagcaatcgc ctttgcgata
    14101 cttgtcgttt ttatcgttcg tgtgttgttg caagtttcta aaactttaga aaaagtagat
    14161 cagactgtag cagaagcaaa tacgacgatc gaaatcgtca caaaagacgt agatcttttg
    14221 tctagacaag tagaaggctt gctggtcaaa agtaatgaac tgctcttgga tatcaatgga
    14281 aaagtcgcaa cgatcgatcc attgttcaca gcagttgctg atttaagtga aagtgtatca
    14341 gaacttaatc attctagtaa aaacatcgcg acgaaagtcg gcggaatcgg taaagcgaca
    14401 gctaaagcga cggttgccgg aaaagtcggt gggacagcga tgaaattttt taaaaacaaa
    14461 aaacatactg aaacgacagg aggaaaataa aaatggctaa aaaaggtgga tttttattag
    14521 gtgcagtagt cggaggaaca gccgcagcaa tcgccgcgtt attgttagca ccaaaatctg
    14581 gtaaagaact tcgggatgaa ttagctgccc aagcggatga tttgatggat atggcttcag
    14641 attacacaga tatggcgaaa gaaaaatcga ctgagttaac aggtattgca aaagaaaaag
    14701 cgcaagatct ttctcaacaa gcaggtgatc tagcaggtag tgtcaaacaa aaagtaagtg
    14761 aatcagcaga tgaagcagga agtgaatctg acgatatctt gttaaatctt aaagaacaat
    14821 cagctgactt atctaatcgt ttcaaaaaaa cggcagaaga tatgaaaaaa cctgcagatg
    14881 aattaggaag tattgctaaa gatacttcag aagatatcat gattgatgta aaagacgctg
    14941 ctggtaaagc aggagatact gtcaatgaag gaatgtcaga agcaaaacca gttgcagatg
    15001 acacaaaaga aatgatgaaa atggcaaaag aagatgcgaa agaagctaaa aaagaaataa
    15061 aagatacaat gacagattca tctacaaatc actaaaatca caaatttata gaataaaaag
    15121 gtgggagcgg actagctctc acctttttta ctcttatttt tctaaaacaa gtaattcttt
    15181 tggtgtagtc gtgaatggca cacagccatc gcttgtcaca tatacacagt cttcgatacg
    15241 tacccctact ttttcaggaa tatagattcc tggttcaaga gagaagcaca tcccttcttc
    15301 gattactaag tcatttcctt ctacaaggga agggaattcg tggacggttg ttccgatccc
    15361 gtgacctaaa cggtgattga aatattcgcc gtagccatag ctgttgatca cgtttcgtgc
    15421 gatttgatca agttcacctg ctgtcacacc tggacggacg gcttcttgtg cggcaagctg
    15481 tgcttcaaga gtgatgttgt atattttttc ttggaagtcg gttggttttt gataagcaat
    15541 tgtacgagta gcatcactgc aatagccatt ccaaacaacg ccaagatcga ataacacaag
    15601 ttcattcggt gaaatcttcg tgtttcctgg tgtaccatga gggcttgcag catttgctcc
    15661 tgcaaggact aatgtgtcga aagacatttg tgaaacacct tgttttttca attggtattc
    15721 gatttctgca atgatcgctt gttcagtcac gccttctttc actgctttaa agccaatctc
    15781 aaatgcaaca tcggcccatt taccagcttc gatcagtttg tctttttcct ctagagtttt
    15841 gatcagttgt agacgttgga tgatggaagt tagatcagtg taagaatccg ttcccgtcaa
    15901 gatatcagag atagcatcga agcgctcgac agtcaaggcg ttcttttcaa tccctacatt
    15961 gccaggctga ccatagcgag cacgaagttc ttttccgatg atctcccaag ggttttcgct
    16021 gtctaaatag ccacggacat catacgccca actactgttt tgagcatctt caacttccaa
    16081 agcaggagtg aaaaggaaag gatcttgttc aagagggata aaaagagcta gtacacgctc
    16141 atgaggatca ctttcgtatc cggaaaagta agcgatgtgg ccagggtcgc tgatataagc
    16201 caattcgact tggtgttgtg ccatccattg acgtagttca ttgattttta cgttattcat
    16261 ttggcaacct actttctaaa ttaattttgt attcaataat tgtaccactg atttattaaa
    16321 agaccaacgt tctaaaaact gaaaaaagta aaaattttca tgaaaacaga gataaaacgg
    16381 ttgcaattct tgagattatt tgatattcta ttttagaaat gtaagacgta ttttcagaaa
    16441 acatataaaa tatgaatagg agaacacaaa tggaaaagca aacaatcact atctatgatg
    16501 tagcgagaga ggcaaatgtt tcgatggcta ctgtttcacg tgtcgtaaat ggcaatccaa
    16561 acgtcaaacc agcaacaaga aaaaaagtct tggaagttat cgatcgcttg gattatcgtc
    16621 caaacgcagt tgcgcgtggc ttggcaagta agaaaacaac aacagttggg gtaatcatcc
    16681 ctgatgtcag caatatgttc tttgcttctt tagcacgtgg tatcgatgat gtggcaacaa
    16741 tgtacaaata caatattatc ttagcaaatt cagatggtaa cgaccaaaaa gaagtcaatg
    16801 tattgaataa cttactggct aagcaagtgg acggcgtgat cttcatgggt caccatatca
    16861 cagacgaaat ccgtggagaa ttttcacgtt caaaaactcc tgttgtatta gctggctcta
    16921 ttgatccaga tgaacaagta ggtagcgtaa acattgatta tgtatcagca acaaaagatg
    16981 cagtaaacaa attggcaaaa agcggcaata aaaaaattgc ttttgtcagt ggtgcgttga
    17041 tcgatcctat caatggacaa aatcgtctga aaggctataa agaagcatta agcgaaaata
    17101 acctaccata tagcgaagga ttgatctttg aagcacaata caacttcaaa gatggtctat
    17161 ctctagtcga tcggatccat aatagcggtg caacagctgt ctatgtttca gatgatgaat
    17221 tagccatcgg tattttggat ggtttattag accgtggcgt gaaagtaccg gaagaattcg
    17281 aaatcatcac aagtaacaat tcactactga cagaagtagc tcgtcctcgt ttaacaagta
    17341 tcacacaacc attatacgat ttaggggcgg tatctatgcg cctattgacg aaaatgatga
    17401 ataaagaaga agtcgaagaa aaaacgatta tcttgcctta tggaatcgaa gaaaaaggat
    17461 ctacaaaata ataaaaggac aaccattcag aggttgtgag cctgccgttt aactctgcgt
    17521 tacaaggagc aatttcaaaa aacagcattt catgtttgat gaatattgtg actcgtgatt
    17581 cggagttggc aggagaacac cgtttattcg ggaaaagggg ctatgacaaa attttgttat
    17641 aatccttttt tttgtcttaa aaaagagaga aagtggttga aattacattt atcgtatata
    17701 aaacaatccg tgtatagatg ctgcattatg ttcaccacca tcaaaaaaat aagggactgt
    17761 gacaatacta ttgtcacaat cccttattac tgtgtattct attaaatcaa tcatctttct
    17821 catctgattc tttggttgct tgattcgctc ttgcataagc tgaagcggtg ttccagtaat
    17881 ctgtatagtt ttcatcggta ccgccaacgc caaatttaaa ggcgcttttc ttcggtccat
    17941 ttttcgccca tagcgattca actgtttttc ctggtgtttg gatggatttt ttattgacag
    18001 taacttttcc aggtgtttga ccagtaaatc cagatacttt tttcttcatc acatcagatg
    18061 ataattcgaa tttctcatca gtgccaaaaa tgtcaggttt tgcttggtaa gcttgattga
    18121 tcagattggc aagataatta gccgaacgta tccttgcttt gctgtccatt ccggtattgt
    18181 catcgtgccc tgcccagcta ctgatggtaa tagacggagt agagacaatt agccatgaat
    18241 ctcggtattc attggtagaa ccagtttttc cgacccaatc tgcttttcct agatttccgt
    18301 ttaagcttga gatggcatct ttgaatggtg tagtgatttt tgcattgatc acactgcgca
    18361 tcatgtcatt catgatcgat gccgttgctt ccgaatagat ccggacagag ttgctttcgt
    18421 gtttataaat tacatttcct gcgttatctg tgatggaatc gatgatatag ccttcttcat
    18481 agacgccgcc gtttgctaaa gcctgaaatc cattggtctg ttgaagcgtc gtgacatcta
    18541 ctgtacctaa aggagcagat tcaacgcccc aattgtcatt tgccgggtag ttcatctttg
    18601 ccaagtagtg ctcgtaagca tattgtttcg atccaccgga attcaacaca tcttgatata
    18661 agtgataagc cgggatattg ttggaccatt ctagtgactc acggacggtt tggaaggtgt
    18721 tcgatccttc gttagtagca ttgacgattt tctcgccagc attttctcct tcttgccaag
    18781 ttgttgcata atctgataca cgggattctg atccgataag ccccatgtcg attgcaggtc
    18841 cataaacaag aactggtttg attgatgagc cagcttgacg ttctgtatcg aaggcatggt
    18901 tattttgatt ctgactgtaa ttccgtccgc caacgaatcc gtagatgcgg ccagttctgt
    18961 tatccatcaa tacatttccg gtttctactt gactgccagc accatcatct aacatgtatc
    19021 cataattttc tacgccattt tgcaatgcag catagacatc tttatcgatt gtcgaatgga
    19081 ttgtatatcc tttattttgg atcgtttgct gtgccttttg ataataagcg tcactgaccg
    19141 atgaatcaga catatcagcg ttgtcttttt cagccaattg ttgtgcaatg attcttgttg
    19201 cttcattcat cacagtataa tacaagaatt ctctgtcagt ctgttctgcg atttgttgtg
    19261 gtagaaagtc ttttgtaagg tcataggctt ttgcttcttc gtattgttct ttcgtaattt
    19321 ggccttcacg atacatactg aataaaacaa aatcttttct ggcaaggccg gcagaaagat
    19381 cttcttttag cgcacctgtg ttcgtgtatg gactatacgt gatcgggctt tggggtaatc
    19441 cagcgatata agcagcttgc ggcagcgtca catcttttgc atctacacca aagattcctc
    19501 ttgcagcttc ctggactcca gcaatgtttt gtcccttatt attacgacca aatggtgaga
    19561 cattcaaata cgtagcaatg atctcatctt ttgaaaagta tttttctact tgtgcagaaa
    19621 gaatgatctc atttgcttta cgtttgaatg ttgtttcatc tgtaaggatc tgctgtttga
    19681 ctaattgctg tgtcaaagtt gatccaccag aagagccaat accagtagct tcagatacta
    19741 atgctcgtaa aacagcttta ggaacgtaac cttggtgttt atcgaagtat tcatcctctg
    19801 tgctgataat tgcagttttc aataaaggtg aaattttatc agatgaaata gtcgtgcgca
    19861 tcagatctgt ctggattttt gatatctctg tattatctgc ataaacaatc tttgacgttt
    19921 ctgtaatgtt tcctagttct gtctgcagtg cttttttagt cggcaattgt gtgtcttcga
    19981 cgagataggc aaaatagcca gcgcctattc caatacctag agctgcgaac atcaaaagaa
    20041 gaacagtaat aaaaacagtc aatgattgaa aaactctaaa aataatctta ggaacaaacc
    20101 atttttcttt ttttcttcta ttctgttttt ttcgagtatt tttgcgtggc aaaagggtca
    20161 cctcaactaa tggttttatt tcgctaatta tagcaaataa tagaacaaaa aaacagacaa
    20221 ggctgttttt ggcaggaatt tcttttttaa ag
//
LOCUS       DAIGWC010000053        20185 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.054, whole genome shotgun sequence.
ACCESSION   DAIGWC010000053 DAIGWC010000000
VERSION     DAIGWC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.054"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            212..1018
                     /gene="proB"
                     /locus_tag="NOB74_001942"
     CDS             212..1018
                     /gene="proB"
                     /locus_tag="NOB74_001942"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HCI1221113.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1015..2262
                     /locus_tag="NOB74_001943"
     CDS             1015..2262
                     /locus_tag="NOB74_001943"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HCI1221114.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2338..2682
                     /locus_tag="NOB74_001944"
     CDS             2338..2682
                     /locus_tag="NOB74_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221115.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2799..3125)
                     /locus_tag="NOB74_001945"
     CDS             complement(2799..3125)
                     /locus_tag="NOB74_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221116.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3498..4700)
                     /locus_tag="NOB74_001946"
     CDS             complement(3498..4700)
                     /locus_tag="NOB74_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1221117.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4817..5332
                     /locus_tag="NOB74_001947"
     CDS             4817..5332
                     /locus_tag="NOB74_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI1221118.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5531..5977)
                     /locus_tag="NOB74_001948"
     CDS             complement(5531..5977)
                     /locus_tag="NOB74_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCI1221119.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6024..7502)
                     /gene="msr(C)"
                     /locus_tag="NOB74_001949"
     CDS             complement(6024..7502)
                     /gene="msr(C)"
                     /locus_tag="NOB74_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCI1221120.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7856..8485)
                     /locus_tag="NOB74_001950"
     CDS             complement(7856..8485)
                     /locus_tag="NOB74_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI1221121.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8469..8933)
                     /locus_tag="NOB74_001951"
     CDS             complement(8469..8933)
                     /locus_tag="NOB74_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1221122.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9420..10688)
                     /locus_tag="NOB74_001952"
     CDS             complement(9420..10688)
                     /locus_tag="NOB74_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI1221123.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10919..11656)
                     /locus_tag="NOB74_001953"
     CDS             complement(10919..11656)
                     /locus_tag="NOB74_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1221124.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11723..12292)
                     /locus_tag="NOB74_001954"
     CDS             complement(11723..12292)
                     /locus_tag="NOB74_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCI1221125.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12420..13292
                     /locus_tag="NOB74_001955"
     CDS             12420..13292
                     /locus_tag="NOB74_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1221126.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13634..14506
                     /locus_tag="NOB74_001956"
     CDS             13634..14506
                     /locus_tag="NOB74_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1221127.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14503..16461
                     /locus_tag="NOB74_001957"
     CDS             14503..16461
                     /locus_tag="NOB74_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1221128.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTLGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16712..17563)
                     /locus_tag="NOB74_001958"
     CDS             complement(16712..17563)
                     /locus_tag="NOB74_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1221129.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17686..18153
                     /locus_tag="NOB74_001959"
     CDS             17686..18153
                     /locus_tag="NOB74_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCI1221130.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18416..18898)
                     /locus_tag="NOB74_001960"
     CDS             complement(18416..18898)
                     /locus_tag="NOB74_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCI1221131.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18998..19861)
                     /locus_tag="NOB74_001961"
     CDS             complement(18998..19861)
                     /locus_tag="NOB74_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI1221132.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6069 a         4156 c         3663 g         6297 t
ORIGIN      
        1 aaactactcc tattctaaca tatccgaggc tgtaaaagac tttctttaca aattcttcaa
       61 gaaattctgc tatcttaaag taaaccatta attcgttctt tttccaaacg actacaagtt
      121 gtacaaaaaa actatttttt acatgacttt actcgtcaaa acaagtagaa tagaacgaaa
      181 ttaatgagtg gatatttgat tgaggtgtca catgcgtaaa gaaattaaaa atgcaaaacg
      241 aattattgtc aaagtaggaa caagtacatt gatttatccc aatggaaata tcaatcttgc
      301 ggcaatcgat cagttagctt ttgtcctttc tgatcttaga aatcggggaa aggaagtgat
      361 cttagtctca tcaggagctg taggcgttgg tatgcataaa ttacatttgt cagaacgtcc
      421 gactttgatt cctgaacagc aagctgcggc ggctgttggt caagccgaac tgatgaatat
      481 ctataatcaa agattcagtg tatataatca acagacggca cagatcctcg tgacaagaga
      541 cgtggtagat tatcctgaaa gtcgtaaaaa tgtgaggaat acattggaac agcttttgat
      601 tatggacacg atccctatcg tgaacgaaaa cgatactgta gcagtggatg aattagatca
      661 tctgacaaaa tttggcgata atgatcagct gtcagccatc atggcaaaac ttgtcgcggc
      721 agaccttttg atcgtccttt ctgatatcga cgggttttat tcagataatc cgactacaaa
      781 tcccgaggct cagatgtatc gctatatcga taaaatcgat gaaaagattc tggcacaagc
      841 aggtggtgct ggtagcacat ttggaacagg cggtatgcag agtaaattaa aagccgcttc
      901 taggatattt gaagcaaaca gcgcaatgat tttagcaaat ggaaaaaatc cggcaattat
      961 ttttgatatt cttgcaggaa aagaagtagg tactttattt aaggaggact tgaaatgact
     1021 gacttgatgc aattaggaca acaggcaaaa gatagcgcgc aacaactagc acttatgcct
     1081 acaaaccgca aaaatgagct acttgttcaa atggcacaaa ccatcaaaaa gaatcaacaa
     1141 gcgatcattg aagcaaatca taaagactta gaaaaagcag tcgaaaacaa tatcagtgaa
     1201 acgatgcaag accgcttgca gctgacacct gagcgaatca atgccatggc tacagagatc
     1261 gaaaaaattg cttcgttaga cgatcctatt ggaaaagtag atgagatgtg gacgaacacc
     1321 gacggattga gaatcggcaa aaagcgcgtg ccactaggcg tgaccggcat catttacgaa
     1381 tctcgtccaa atgtcacgac agatgcagct agtctagcat tcaaatcagg gaatgccgtt
     1441 atccttcgcg gtggcaaaga agcattcttc tcgaatcaat tattagtcca attattgcag
     1501 caagtactgg tcagtgctgg cgaatctcct tatgccatcc agtttgtcga tgatacttct
     1561 catgaaactg caggacagtt gatgcgattg acagaatact tagatgtgct gattcctcga
     1621 ggcggagcaa aattaatcca acgagtcaaa gaacaggcaa cggtacctat cattgaaaca
     1681 ggtacaggaa ataatcacgt atatatcgat aaagaagcac agttatctat ggcagtgaac
     1741 atcatcgtca atgcaaaagc ttcccgtcca tctgtctgta acgcggcaga aacattgctg
     1801 atccattctg agatcgcacc ttttttcttg ccagctattg aaaaagaact ggtagaacac
     1861 ggggtctctt tacgtgcgga tgctcgtgcg ttagaatatc tagagacggc tgctttagca
     1921 gaagacacag attgggatac tgaatatcta gattatatcc ttgctgtcaa agtggtcgat
     1981 tctttggatg aagcaattgc acatatcaat cggcataata ctaaacattc agaaacgatc
     2041 gtgacagata gttatgcggc tagtcaacgt ttcttaaatg aagtggacgc ggcggctgtc
     2101 tatgtcaatg cctccactcg ttttacagac ggatcggtat ttggttttgg tgcagagatt
     2161 ggtatctcta ctcaaaagtt gcatgcccgt ggtccaatgg ggttaaatga attaacttcc
     2221 acaaaatata tcatttatgg cgatggacaa atccgcgaat aatgtttcgt gtgaaacatt
     2281 attcccgcct tttgcctttt ttctgtaaag gttctatcca actagaaagg tgtcaatatg
     2341 tttgaaattt taatgatttt ttttatttac cttatttctc tgaatatcgc tgcttttctg
     2401 ggagtcggta ttttatccct tttctttcaa ttcaaaaaac gaagcatagg gagtcaacgg
     2461 gaaaaatggt cgcagtattt tgacaaaatc gggcaaaaag ggctggttac acgcttgcac
     2521 attagttaca tggttgcatt atgcttatta gcgacaatca attactattc ttttttcgat
     2581 cattcaatcg cttatacgat tacgctactg attgctggga tttttcactt atcttataaa
     2641 tatcagctga ataaaaacca cttgaatcgg actttccgct aaaaaatatc cgtacgataa
     2701 gtagagtgcc ttgaagatcg gcaaaaaact gccggacttt ttagaggctg tgacaaagat
     2761 tttgtcacag cctctttttc catataaacg gcgttcgcct accagctgcc tggtaaatct
     2821 gtttcctctt cgttaagaag cgaaaatccg tcaaatgttt cgccatcata ataacgaagc
     2881 agctcatcca tggacaagtt catcgttttt tctttttctt cttccgctga ttcagccagt
     2941 agctgttccc gatacacctg atacatacca gctatttttt gctgcatcgc ttttctagtt
     3001 tcaccttccg cattgattat tggcaattct ttgatatagc cacgataaat caaccgatca
     3061 tctgaaaatt caatgggtaa ttcaacgagt gtcaacccga cttcctgaaa atattcttcc
     3121 agcatctatt atccccccat tctttttctt aaatgaattt tagcttacct actgaaaatt
     3181 ttccagtttc attattttga gaaaaaaagg gaatgtgaca aaaatcgtgt cacatcccct
     3241 ttttccgaat aaatggtgtt cttctgccaa ctcctcaatc ataagtcaca atattcaaca
     3301 aacatgagaa actgtttttt gaaattgttc cttgtgattc agagttaaac gacagtctca
     3361 caacctcttg gtaaacggcg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
     3421 aaaaatatga gaagctattt ttgtttggct gttcttatga cttgatgcag gacagctttt
     3481 tcacaacctc tgatttctta ttcttcttca tttgtagcaa aataattacg gtgataaatg
     3541 atacaacata cactgataag aacaatggca cctgcaaaat aaaacgcata gctttcacca
     3601 atatgttcac caatcacacc tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca
     3661 aaactatagc tggacgaagc aacgtttcgt tgcagacctg gtatttccat agcaatcgtc
     3721 gtcaacagtg tattgataat tccttggaaa aatcctgcta acacaatgct gatcggtaca
     3781 aggactggca tagaagttcc agctcctaat aacagcaaac aaataatgaa taagacaaat
     3841 gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc
     3901 gaagcaatag ccagaagcac accccagcca aaaaatacaa aaccgacttc taattcagaa
     3961 tagccaatca ataaaaatgg cgcatacgca agtaaagtaa agaatccgaa attatataac
     4021 aatgcgatta gtccaactga acgaagttta tgattgctta acgctttgac accttcccaa
     4081 aggcctactt ttctctttgg tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa
     4141 ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac gccatgaacc actgcccaag
     4201 accccaccga ctagagggcc aacagccatt ccgcagccaa gtgctgcttc atacatcatg
     4261 attgcttttt ctgtgttacc aactaaaata ctgacgatcg ttgctaaagc agtagagaca
     4321 aataaagcat tcccgacacc ccagccggca cgtaacccaa tcagcattcc gatattccca
     4381 gataatccgc caagaccagc gaatacaacg atgataaaca atcctgtcat caatgttttt
     4441 ttcaaaccga tccgactaga taagaaacct gtaaatagca tcaccacacc agtgactaac
     4501 atgtaactag taaataacag ggtcgtttca gctggcgtag cgtttaactg tgcagcaatc
     4561 gtttttaaga ttgggtctac tagacccact cccataaaag cgatcataca ggtagctgct
     4621 acaactagcg ctgaactttt cccctttgtt tcttcatttg tttgttcttg tatatctatt
     4681 tgattctcca atatttccat ccctttctct ctattagcat catacatgat ttattttaca
     4741 tgtaaatatg cacatgtaaa acgtggaaac tttactgtga tataataaag aaaataagac
     4801 gagaggtagg atttttatga atactttagc ctatatatta ttatgcgtgc ttttatccaa
     4861 accacgttct gggtatgaat tgaagcagct gatcacaatt ttttgggaag cccatcacag
     4921 tcagatctat acaacgcttg ccaagttaga ccagcagggt tatgtgaccg ttttggacaa
     4981 agacgagcac tctcaaaaaa agatctacca cttgactgat gaaggacgtg ctcttgtaga
     5041 ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa gatgaatttc tagcaaaaat
     5101 ctatgctttt tcgacgctcg ataaaacaac agctactgga ctgctattca ctagagaaca
     5161 acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg aatgacctct cgctagacaa
     5221 gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga attatgcttt gtcagcagga
     5281 actccaatgg tgtcagcaag taagagaaca aatgcagcag ttttttgagt aagggataaa
     5341 cagaaccttt ctagaaatat ctattgaaga gcaaattatc ttcaataaaa gagcaataca
     5401 gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc tatcgttcgg atcactattt
     5461 ttctagaact gcattcaaga gactatgaca aaaagcatgc caaggccttt tttcaaataa
     5521 cagtgttcca tcattcatta ctttgaattg cttttagcac acttcttgaa agcgggccaa
     5581 cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat tttccaagca ttcatataag
     5641 cagagaataa ttgatcaggt attccttgtt ccatgatcac accgaataaa gacatacatg
     5701 tcaccattcc taaaaccatc aagcatgaaa tagttaagat catttggacc ttgctttctg
     5761 gatttactgg tagtttaaag gcaatttttt tcgccagcac accgatgatg aagacatcca
     5821 aaatgaaagc caccacgaat ccaggcacta gaccaatcaa caaacttgat aaatgaagat
     5881 cttgatgcag ccataaatta tacgcgctca tccccaagac catcaaaaaa cacatcattg
     5941 ttgtaaaaat tattccttct tttttatttg taggcaatct gtaccactcc tttaaatttg
     6001 tcacgaaaat catcgtagca catttaaaaa tttctcgtaa gtactttttt tattttctgc
     6061 ccttttattt cataaacttc atcagccgta cgctcgacaa agtaagaatc atgagaagta
     6121 aacaaaatcg ttcccggata tatttgcatt agcttctcta aagcttcgat cgttgccata
     6181 tcaataaaat tagtcggttc atctaacagc aacacattac ttggcttagt aaaaagcaaa
     6241 gcaatcgtca gacgggtcgc ttctccccca cttaatgtac ataacggttt cgtcaaagtt
     6301 tcctgagcaa accctaagtg attcagcaaa ctacggacaa gcgattctga aaactctgtt
     6361 tgtctcatga caaaacgaat gatggattct tcagatgtca tttgataacc cttttgctga
     6421 tatacttgaa agcttacttt cggagagaga aggattcctt ctccttgttt gcggatatgt
     6481 tctaataagg ttgtcttacc tgaaccattt tcaccgacaa tcgcgatttt tttacctaaa
     6541 gaaaactgaa aatcaccatt taccagtaat gttctcccac ttctttccaa ttggacattt
     6601 tgtcccatga tgggatagcg gctgtggagt tcaagagatt ttggtactgg aaaacggatt
     6661 tgtttcatct gctgcggctt ggttgtttct cctatttttt ggagtcttct ctctaatgtt
     6721 ttcgcattct tttggatggc tttttgtaca ctgtcttttt gtttagagga agacaaccga
     6781 tccggtctga tttgttgctt tttcttttta ctggacactt tttccaactt ttccgcttgt
     6841 tttttctttt cttggatcga tttttccaat cgttttttct ctttcatgat cgactctgct
     6901 tctcgtagct gagtcttttt ctccaattcc ttttgagtga gataggcact ataattcccc
     6961 gaaaactctc ggatttctcc gtcttttact tcccagattt tcgatgctag ctcatctaga
     7021 aaatagcgat catgactaac aaaaaccagc gtaccataat aataacgaag ctcttcaatc
     7081 agtcgatcaa tactttttct atctagatgg gttgttggct cgtctagaag catcccttgt
     7141 tcataagaag aaagaagacg tatcaactcg atctttcgtt cttcccctcc gctccatttc
     7201 cgctctgaag tttcttccag tcttaactgg aaatgactgg ctaattccaa atttaggtcc
     7261 tttgcttcag cgagataggt taattgaggc aggtagttga aggtgatctc tgtttggatt
     7321 ttcccatgat cgggaaaaag ttcaccggct attagtttga gcaaagtcga tttaccgaca
     7381 ccattttctc ctatgatccc tatacgatct tgctgataga cacgaagaga atcaatagat
     7441 agttctagct ggttgccaaa gctgacttgt agatttgtta tatttactgc taaattttcc
     7501 atatgtttta cactcctatt tcatgtaaaa caacaattat cgatactaaa aaagagcaga
     7561 aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta ctctgaacga aataactatg
     7621 actaaatcac caaatctgtc atagctttca cctattctac tgtcgttcga aaaaatggac
     7681 atactccatc catgaaattg ttgtttatac atgtcttttg aatttattta gttgttattc
     7741 aaaagttcga aacgtaattt catcgatgca gtcatttttc cgacctcctt ttttattagg
     7801 ttaccacaca cgattcaaaa aaagcaatag ctactgaata gtaactgaaa accttttatt
     7861 cgaacgtagt gatcttttct ggtgctaaac gaacagactc gtaaccttct tctaccgctt
     7921 ttcctattga taaaataata actggaacat aacggtcttt atccaaacca aatgcctctg
     7981 ccaactgatc tgcttcgact ccaccaattg gatttgtttc atagccatga tcacgcgcaa
     8041 ctaacatgaa ttgcatagcc gctaagctag aatcgacttt gactacatcg ttcatttctt
     8101 ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa ttgttgatct ctgacttctt
     8161 ttggcatctt ccctgattcg taagcttggt tatagatttc ttcgccatat tcgtaacatt
     8221 gcatatcgcc aaaaatcatg accattgcag aagaagtatc attttgtctc gtattgaaac
     8281 ggatcaaagg acgcaagatt tcttttgctt cctcgctttc agcgaccaca aagcgccatg
     8341 gttgcatatt gacagaagaa ggtgcagtcg tcgcttcttt gatcatttcc agcatttctt
     8401 cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga tcttctacca gtcataattg
     8461 ttgaaaaatc atttttttgt tccattatta ttaacctctt tcgtttctgt tgttatattg
     8521 caaagttggg tattcaattt atctaaaagt gttagaaatt gtttcatttc tacatcgctg
     8581 aaagccgggg atagcacgga acctgtatct ttatggtcca tttcacaatg ctcgattttc
     8641 ttctgggctt tttctgttag cgctacatac acttcccggt tgttctgagg atttctctga
     8701 cgcgaaacat agccatttgc ttccaatacc ttcagatgac gagtaactgc tccttgatca
     8761 atctgcaact tttcttgcaa actgctttgt agcaatggat tttcttcttt cagtctcatc
     8821 atgatctcgt atctagtaag acttataccg atattttctt caaagatctg gacgattttt
     8881 tgatcggcta atttgatttg atataaaagg tgactaatct cttctaaaga cataatttcc
     8941 tcctttctaa taattgactc gtcaacgatt gacttgtcaa taatagaata aaaaaagaaa
     9001 aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc aatagaaaag tatagagaaa
     9061 agaaattttt tgtagaatga acggaaaaaa tgataaagaa agcacaacgc taaaaccaag
     9121 attattgatt cttatcaaac tatagaagat agctcttctg cagtagaaaa ttttacaccg
     9181 ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg aatattagaa attggatcag
     9241 tatgcttaaa cagtaataaa aaagttatga caagatgttg tcacaacctt ttttgagtaa
     9301 acggtgttca aaaacttgca tctgcggtaa taagttcaac caaacaaaaa acatgaaaat
     9361 ctgtttttgt ttggctgttc ttactacttg atgcagggca gctttttcac tacctctttt
     9421 taataaccat aaaatcctat tccttcatat ctccagccca tcggtgttag ccaatctctt
     9481 tccttagcac tcaaggtata gtgatgggta ccagtttttt catttggatt aaatagtcga
     9541 taaattggct tggaaccacc agaataaaaa cttagacctt cataacgcca accgattttt
     9601 gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat ggtctccact gtaaggattg
     9661 tataaacggt agacaggttg tccgctgttt ggtgcttgcc aagcaatccc ttcatattcc
     9721 cagcctacag ttggcagata atttttttct ccggcattca atgtatataa atgttctcct
     9781 gtatgacggt tatacagacg atacatcgga gaagttgaag ttggtgctgt atcatactgt
     9841 gtcagattat aggtttcgat tacattgttc aatgtagaac cataattagg cgcagtggca
     9901 taacgacctg ttagccaagc cgtagcatct ttgtaagagt tcgtattgct tttccatgca
     9961 ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct tcaataccgt tacgttatct
    10021 tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg cattcaccgt aatccattgc
    10081 ccattcacat attccgaagt aggcatcgta acagattggc cattatagct tcctttaatc
    10141 ccaaatagat tgtaattagg ggcagaagcc aaagtactgt tcccccagcc actttcaacg
    10201 atggcttgag caatcatgac tgatgcatat aagtcattgg cacttgccaa actttgtgca
    10261 gttgaggcaa tactatcaat gaacgcttgt tgagaattag cagatgagcg agcataaaaa
    10321 gcatagccag tatagttttc gaattcagac aaatctgctt gatgggtatg tgtcaatgtt
    10381 tgcccatctg tcaattggtt cgtgatttct tctgcattct ctggattgtt ctgagcttct
    10441 gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt cagttgttgg ttcttcggtt
    10501 gaaattgtat tttctgagac agtagctgac tgcaaagtac tctctgtatc gttttcaatt
    10561 cctgtttctg aagaactcga tgtctgagtt gcgacagttt ctgtcgattc ttcagctagc
    10621 actgttgtgt tggcaactgc tagatttcct aaaagaataa cgctaaataa taaattcttt
    10681 gctttcatct tttttctcct ttgaattatg aaacttttcc taaataacag tgtaactaaa
    10741 aaagtaaaag caagtcaatg tccatattta aataacattt gtttcttttt gataaatttg
    10801 ctttttctac ataaaaagac gtaaatgaag aatattcttc tccattcacg ccttaaattg
    10861 atggtcgttt gaataactat ttaacaagta attctctttg gatattatcc gttatggatt
    10921 atacttcctg tgtcgtcgga cggataatca tgttactgac agacatccgg tctggcgttt
    10981 ctatcgcaaa tgctacagca gaagctatat cttcggaggt caatccccat tctttttgcg
    11041 cttcatgaag ttcaagagca gcctttttgt cgctgatggt ttgatataat tcagtttgaa
    11101 cagctcctgg agagatgatc gtagatttga tgttattttg ccgttgctct tgacgtaatc
    11161 cttccatgat tgcacggaca gcaaattttg ttccgcaata aacggcggaa tcaggataaa
    11221 caacatgtcc cgccacagaa tcagttgaaa tgatatgccc agatttttgt ttttccatga
    11281 ttggaagtac ggcggaaatt ccatttaaca cacccatgat gttgatatca agcatatttt
    11341 gccattcatc acggtgacct tcaactaatg gagcggttgg catgattcct gcattattgt
    11401 acaatacatc gattcgaccg aacttttcca tcgctaaatc gataactgct tggacttgtg
    11461 caaaatctct tacatctgct gtttgaatat atagctcagc ttctggtaaa gattctttta
    11521 ttgcttttag gcgatcttct cggcgtgcag ctataactag tttagcccct ttttctgcta
    11581 atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc catgatgaca atcacttttt
    11641 ctgataaatc attcattcta ttctcctcct gttttgaaaa atctcttgct tatactcact
    11701 atctcttatt tcatcttact gttcaaataa tccgttcgac aggtttgacg attttggcag
    11761 ggattcctgc aacgatggta ttgtctggga catctttcgt aacagttgca ttcgctgcaa
    11821 caatggcatt ctcgccaatc gttacgcctg gcagaatagt tgctcctgct ccgatccaag
    11881 catttttctt gatgtggatt ggctttacta acaagcctct tcgttctttt ggatcggtta
    11941 gatggttcac cgtgatgagg ttgacacgag gaccaatcaa tactgaatct tctaaacaga
    12001 tgccacctaa gtcaacgaac atcacttgac gattgataaa gacatttttc cctatactaa
    12061 tatgtttgcc gaaatctgta taaaaaggca gcagaacagt caccgtatca tctactttgt
    12121 cactaatgat attttctagc cgtttgcgga tatctgctgg ttcatggtac ccagtattca
    12181 gcgctgctaa aggctcttcg ttttcagctt ggatctgatg gatcacttca aagagcggat
    12241 ccgttactcg aatctcttta ttgacgattt gtttttcgat gaggcttgtc attttgctcc
    12301 ctccttttat ccttacttta taacggacgg cttatcatgt ctaatactta taaaacatac
    12361 ttaactattc cttttaacta tacttagtgg tatgcttttt taaaaacagg agggaaaaaa
    12421 tggatattcg tatactgacg tattttttag cagtagctag agaaaaaaat atcagccgag
    12481 cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa acaactgaaa gatttagaag
    12541 aagaacttgg tgtgacactt ttcactcggg gctcccgaga gatacagttg acggattctg
    12601 gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt ggtagaaaaa acggcgaaca
    12661 atttaacaaa tgacgcaatc atctctggag aaatctacat tggcggaggc gaaactaaag
    12721 caatctcttt catttctgat agccttcatt cgttgatcaa ggcgcatcct gatatccagt
    12781 ttcatttata tagcgggaat gcagatgata tcatagacaa actggatagc ggattacttg
    12841 attttggact cgtaatcgaa ccgacaaaca aacaaaaata ccagtcattt cgactgccag
    12901 cccaagatcg ttggggactt ttgatacatc gaaatcatcc tttagcaaag caaaccgtca
    12961 tccatccgca ggaactgaaa actgttcctt tgatcatttc ccggcaaacg tcagtggaca
    13021 gtcaactagc tgaatggcta ggtttcagca tagatcagtt atcgatcgtc ggaacatata
    13081 acttattgta caatgcttct ttgatggtcg ataacgggac ttttggtgca ttagctctag
    13141 atgggatcat caatacttat gggacggaaa aaatattcat cccactcgat ccgccattac
    13201 aagcttcact gaatctcatt tggaaaaaag accagcctct ttctcctgct gctcgtaaat
    13261 ttttagatgt cctaacggag aaatacagtt aagtagagtt tttttccttc gctttcagct
    13321 ttttaacaac gaataagata agcaaaagat ccaacgatta aataacataa gtttcttaat
    13381 ttatttcttc cttttatttc tgataattcc agtaaattac tataattata aaaaaagaat
    13441 tgacaaaaca taactgtcta tataaaattg attacgttaa caataattcg tttcatgtga
    13501 ctggatcata ctaggcatga aaaatctctg aggaacatgg tttccctagg aggtttttcg
    13561 tgtctatttt tgtttggccg caatcaactg gtctagcaaa cgtgaaaacc aaatcttcaa
    13621 aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa aatgcagtat tggtagatga
    13681 cggtggacag gaaaaagtag ctattggaaa agggattgga tttgacagaa aaagaaatga
    13741 tttgattttt gatcgtgatg tcgaacggat atttgtcatg gaaccagaag gtcaaatcaa
    13801 gttgcaaaat ttacttaatc agattgatga acgcttttta tttgcagcag aaacgatcat
    13861 tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa catgtattga tcgctttgac
    13921 cgaccacatt gctttttctg cggagaacat taataacggt atcgtcatcc gcaacaaact
    13981 tttaagagaa atcgaagtgc tttacagtga tgaattcagt attgctcaat gggcagtaga
    14041 gtatctgaca aaagagcttg ggattccata tacttatgac gaagcaggat atatcgcaat
    14101 ccatattcac agcggacgaa gcggtcggaa caataaccat cgcagtatcc gtgaagtgac
    14161 gattgtatct gacatcatcc atttagtgga atcagaattg gaaacagata tccattcaga
    14221 accattttca ctgaattatt caagactggt gaatcattta cgactgcttc tacaacgaac
    14281 ccatgcgcaa caatatgctg ttttagacac ggaaatcgta gaaatggtca aacgaaaata
    14341 cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg ctgaccaaag aataccagct
    14401 cgcgatcacg aaagaagaac tgggttactt ggccatccat atcgagcgtt taagaagcgc
    14461 aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa aattgaaagc atatctacaa
    14521 cgaatgggac gttcccttca acttccagtt gcggtcttac ctgctgctgc tttactagta
    14581 gggatcggaa actggtgggc atcttatagt aacgacattg tcgctcattt tttacaagct
    14641 ggcggtaacg cagttttagg tcaattacct ttgctgtttg ccgttgggtt agcactaggg
    14701 atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt tggtcgcatt tgaagttcca
    14761 gtaaatgttt taaaaactga ttcagtagct actttattga atatcaaacc agaatcagtt
    14821 gatccatctt ttgctcagat cagtaacgta tttattggta ttattgccgg attgattgcg
    14881 gcagctcttt ataatcgttt ccacgaagca aaattaccga tggctttatc tttctttagc
    14941 ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt tgctgatcag tgcagtgcta
    15001 ctgctcgtat ggcctccggt ttactctgct ttagtttctt ttgctaaatt cattttgagt
    15061 ttaggctggg gtggtgcagg tctttatggc ttcttcaacc gtttactgat ccctacagga
    15121 ttgcatcaag caatgaactc cgtgttctgg tttgacgtag caggaatcaa tgatattggt
    15181 aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa tgtatcaagc tggatttttc
    15241 ccaatcatga tgttcgggct tccagcagga gcatatgcta tttacagaaa tgcacgtcca
    15301 gaaaacaaag caaaaacagc ttccttgatg ctagcagcag cttttgcttc attctttact
    15361 ggtgtgacag aaccacttga attttcattt atgttcgttg cttggccatt atatgtcttg
    15421 catgcaattt tcactgggat ttctttagca gtgagtgcat tcttccattg gacagcagga
    15481 tttgccttta gtgccggatt tgtcgattac ttcctatctt tgaaaaatcc gattgcgaat
    15541 cagccattga tgttgatcgt ccaaggatta gtaacagcag tgatttacta ctttggcttt
    15601 aactttgcta tcaaaaaatt ccatctgatg actcttggcc gcgaggaagc agatctttca
    15661 gatgacgata ctgcaacgac taattcagac aataaatatg cggcacaagc aagcaaaatc
    15721 tacgctgcat taggcggagc cgacaatgta acttcgatcg ataactgtac tacacgcctt
    15781 cgtttgcaag tcaaagatac aggcctgatc gatcaaaata aaatcaaagc cactggcgta
    15841 cctggtatga agatcatcga cggaaaaaat gcgcaagtca tcgtaggtac agaagtacaa
    15901 ttcgttgcag atgagatggc aaaactacat ggtggtgctg cagcacgacc tgcacaaaca
    15961 aacaccgtgg ttaaaacaga aacatttgcc ggtgaaacga tcgaacaaga tatttacgct
    16021 atcgcaaatg ggaaactgat tccaatcact gaagtttcag atgatgtatt cgcggaaaaa
    16081 atgatgggtg acggctatgc tgtattacca gaaaatggag aaatcttctc tccaatcgct
    16141 ggtacgatca caaacatttt cccaacgaaa catgctgtcg gaatccaaac agatgctggt
    16201 atcgaagtct tgcttcatat gggcatcaac actgttgact taaaaggcga accattcact
    16261 ttatatgtag aagaaggtca aaaagtcgca agaggtcaat tgattgcttt agttgatctt
    16321 gccgctattc aatctgcagg caaaaacacg gatatggtcg ttgtattcac aaatggcgac
    16381 aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa aagcaaatga taaaatcggc
    16441 tctgtttcca acaaagcctg agccatcgtc ttccccagac ttttttatcg ataaacaaac
    16501 aggagctgag acaaaaatct tgtctcagct cctttttccg aataaaaacg gcgttctcct
    16561 gccaactccg cggtaataag tccagctaaa cgaaacatat gaagagctat tttttatttg
    16621 actcttctta ttacttgatg cagaacagct ttttcacaaa atttttcttc atactcaaaa
    16681 ctaatcggct ttttcacaac ctctttatac attattcctg atccaatatt tcttttaatg
    16741 ctgcttcaag agaagttaat ggttttccca atactttttc taaatcatca gaggaaatag
    16801 ctaactgatc ctttttaata tcatgttgga tcgctaaaaa catgtcagct gcttcttgag
    16861 ggaatccggc ttcttttaga ttttcgacaa acgctgcatc acttgcttca ataatttcta
    16921 actctttacc tgtcgcacgc tctaatgcct tggctaattc ttcatagtca gttagattgc
    16981 cggataattc taagatttct ggagagtcac tttctactag tacttttgct gcagcttctg
    17041 catattcacg tttcaatgcc caacctgttt ttccatttcc tgcagcataa acgaattgac
    17101 cagtttttaa agcctgccca atgataggta attcattctc tacataccaa ttattccgta
    17161 aaaatgtatg ggaaatacct gaatccttaa tcattttttc agtgaattgg tgatctggcg
    17221 ctaatacact gatcgagtga tcggcatctg caaaacttgt ataagcgata taagataccc
    17281 cagctgcttg tgctgccttc actacattct tatgttcggc ttgacgattt cctggaacgc
    17341 cagagacaaa aagcaatcga tctattcctt tcaacgcttc tttcattgag tctaaatcat
    17401 cataatcacc aatacgtata ttaaatccag cttctttcag tgcttctcct ttttcttcac
    17461 tacgtactag tacatagatt tcattttgtg gaaccatctt ttttaagaat tccagcgcat
    17521 aaccaccaaa acctccagtt gctcctgtta ctaaataatg catatttgcc actccctatt
    17581 ctttttattt gttaagattt acagctgtac atttataaat tacaccttta tcataaagag
    17641 tgtggtaaga taagtcaagc aaaaaaaatg aaaggatgac aactgatgaa gtattctctg
    17701 caatttagtg atgcaatcca tgtacttgcc tatattgaaa tgtttcaaga tacccgatca
    17761 ctttctagtg agatgattgc cagtagtatc gaaacaaatg cagcaaatgt acgtaaaatc
    17821 atgagtcagc tcaaaaaatc cggtttgatc tttacaaaaa ccggaaaacc gcagccttcc
    17881 cttgccaaaa gtccagatca gatttcttta ctagatgtct atcgcagcat cgaaggtaat
    17941 acacagctta tccaagtcga tccaaaaaca aatccaaatt gcgtcgttgg tgcgaatatc
    18001 caagaagctt tagaagaaag ctacgctcgg ctgcagaaaa aggcagaaga agaaatggct
    18061 aagatcacac ttgatagtct gatacataaa atagccgttt tggaaaaaga aaaaagacca
    18121 gaaaacacag gcctcgtaga gagattttta taattctctc tactgtgcct gcatttttct
    18181 gatcggaatc gtctacataa attcttttat tctccggggg acaaaagcct tgtcatgccc
    18241 ctttttcctc tctaatgctc aggtcaaagc gctgaagtca tgacgtcttg ataaacggtg
    18301 ttcaagtagc tgaccctcgg cattagttct gaaaaatgca aaatatggaa agctatttcc
    18361 catttttcct ctctaatgct caggtcaaag cgctactttc acgacctcta tattatcatg
    18421 gtttattgac taccggtatc cagatttctc ccatatattt cccgttggta actcccattt
    18481 cgactacagc atttggaccc ccaacatagg cgtaatcttc tacttctctt aaaacatgcc
    18541 caaaggccgt attcgtcaaa tcatttctta attcttcagg cgattctgct aaagcgctta
    18601 caacaagata cgttcctttt gggaatggga tgattcgcgt agtgtttgga acatcctgac
    18661 tcgtttgaac accgacatag tacatcattt tcccgttata gggttcgttg actgtaaaga
    18721 aataatgatt ttcagcagct tgtttcaatg catctattgt tccattaccg ataacttttt
    18781 gctcaaatgc ttgtttctct gcagccaaac cgacaaaatc cgtattgcta ctcttcaatt
    18841 ccacaccaat acccgtcacc gtaaaatctg gtttttcttc gatcctatac tttgccattt
    18901 ctcccaccct ttctattata ttaagttcat cttacataaa attaaaggga aatgacacga
    18961 ttacgctctt ttttctaggg atatttttat tttttaacta tttttttgct ttcactgcaa
    19021 tccaaatctc actgtaaaca ttactgaaat cctctcccca ttttgtaaaa gagatctcgg
    19081 gagcttcgac taacccataa tctgaagaag gaagccattc tgcatagatt ttcccccaag
    19141 tatcttgtaa agtttgggga aatggccctt tattaggaaa aatggcccaa gtgtgttctt
    19201 ctatagcaag catttctaaa tcagcgtacg gattttcttt tgtcgtagca aagccaatca
    19261 tgtgcatcaa actgcccttt tcttccaagc ggtctccatc aaatccataa gaaacgttga
    19321 ttacttgatt tggatataaa tctcctaact tatgcatctc ttccctttga gtctccgtga
    19381 tcgtctgcgc taacttttgt atttcttgat tgactccttc aaatttgaca ggaacttttt
    19441 tcgccacacc tgccacataa aactgttctt tcttttcgat acgaaattcc atcgattttc
    19501 ctcctctgac atcaataaaa aatgtcaagc gtggaaaaga tttttgtatg ccgtatctgc
    19561 tgatttctga aggcagatat cctgaccaat cacgaaaagc tcttgaaaaa ccttcgactg
    19621 tttcatatcc atatctaaac gccgtttctg tcactcttga tccatctaga agatcgcgat
    19681 tagccaaagc caatctacgg tttttgatat agtccattag cgacatccct gcaataaacg
    19741 taaagatgcg ttttaattga tattcagaga ttcctgtatt ttcggctatt attttatagg
    19801 aaagtccttc tgtcaaatgt tcttcgatgt aatcgatcaa ttggttcaga tctttaagca
    19861 tatttatctt cctccttgat tgccttttta tcatattatc aaagaaagtc aattacttga
    19921 tgaatcagga accaatttag tcagatgtag aaaatgttgt atggatctaa agaaaattct
    19981 caagcagcgt ttcgtaacgg ataattggta ttatctgcct atctatgttt tacctttaga
    20041 aaaataaatt ttggggaaga cagattctaa gtaaacaaag cggtaaaaat atcttttatt
    20101 cccttagtta atccgcttac tacctactgt acaaagcaaa ttgttgttca aactgctgat
    20161 cagaacgctg cttggatttt tcttt
//
LOCUS       DAIGWC010000054        19889 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.055, whole genome shotgun sequence.
ACCESSION   DAIGWC010000054 DAIGWC010000000
VERSION     DAIGWC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19889
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.055"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            5..928
                     /locus_tag="NOB74_001962"
     CDS             5..928
                     /locus_tag="NOB74_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCI1221133.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDGSVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRST
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            946..1209
                     /locus_tag="NOB74_001963"
     CDS             946..1209
                     /locus_tag="NOB74_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221134.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAAAVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            1221..1550
                     /locus_tag="NOB74_001964"
     CDS             1221..1550
                     /locus_tag="NOB74_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HCI1221135.1"
                     /translation="MMIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSKYQNEIDEFKRKDQEELYKPK
                     RGRFKFV"
     gene            1547..1873
                     /locus_tag="NOB74_001965"
     CDS             1547..1873
                     /locus_tag="NOB74_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221136.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKTWQQKTARNPAYRNSLIVQEVV
                     LDEGTT"
     gene            1857..2195
                     /locus_tag="NOB74_001966"
     CDS             1857..2195
                     /locus_tag="NOB74_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HCI1221137.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            2195..2587
                     /locus_tag="NOB74_001967"
     CDS             2195..2587
                     /locus_tag="NOB74_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HCI1221138.1"
                     /translation="MIKTRDQSIFDELFKISQNKLGYKTYDYKTLEDVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQLSDMASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            2598..3110
                     /locus_tag="NOB74_001968"
     CDS             2598..3110
                     /locus_tag="NOB74_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HCI1221139.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELSLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            3156..3524
                     /locus_tag="NOB74_001969"
     CDS             3156..3524
                     /locus_tag="NOB74_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HCI1221140.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFVDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEDESITLDELDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQVE"
     gene            3578..3865
                     /locus_tag="NOB74_001970"
     CDS             3578..3865
                     /locus_tag="NOB74_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221141.1"
                     /translation="MTNISDIERMTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQ
                     AEKKVGKKTVPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            3882..7001
                     /locus_tag="NOB74_001971"
     CDS             3882..7001
                     /locus_tag="NOB74_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCI1221142.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFSAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQKLVVA
                     IGAIVAAIGPLIFMIGSVIIWINRVKVAFKALSESSKLFSGLSKAMGLLTNPVFLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTVQEAPGKAADWIKNKWTGTKEFFSNLWSSIANSASEIWNSLKEGVIS
                     VIDDLVSSAGEKWEGFKNTISTAWKTITSKIKSGFDFILKYIGPFVSSFSDVFSNIVK
                     AITSIFAEVKNIIVNAWEIIKSLIAAPLLFIIDLITGDFEQMKEDLDLIWNTLVQSVV
                     NIWTSVKNIFTEYIGAIVNSAVSLWTGFIQSISNIWNEVVYQATMIWIDLKLFFTNLW
                     IDIKYSAIQMWINLKFSIIQTWIDTKYGAIELWNNLKQWFFQTVNNIVQTLIKSWNSL
                     KQGTIDLFNNTVQGAKDIWTSFKSWIGDLITGTKDNIIQGWENLKQGTIDTFNNLVNG
                     AQEAWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDSFLEGLQNAWKSVQDFVG
                     GIGDWIREHKGPIQYDRKLLIPAGQAIMNGLNKGLTGGFNDVQNTVGSMADFIAELFN
                     ANSDVDIAANLKNANKNIGAQVEHKINMGGSTKPAVFKINLGRQSFRLFMDDISQAMG
                     EGADINLEF"
     gene            7034..7801
                     /locus_tag="NOB74_001972"
     CDS             7034..7801
                     /locus_tag="NOB74_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HCI1221143.1"
                     /translation="MYSFKDTTINLTSSKRFLPTSAMMYDGMYLEDLIDGYQTLTVEG
                     REMLSVEVEQQEIQIGSIITNQKIPSRTLKITYKLEDRDPEKLQFKFKELLNYLYRNE
                     DVEIRFHDELDYYYYGRYTSTDTVPGDSNSIISSFNVFCADPLKYTKECVSDGYIGNP
                     IQFPITPRKIEVTLSMNNSIKITNGEQNITITDAAIKTGDVLVFDFSDEQVTVNGEDC
                     TSMIDLESDFENFYLKQGQKITSNNGKLKIFYRGATI"
     gene            7798..10629
                     /locus_tag="NOB74_001973"
     CDS             7798..10629
                     /locus_tag="NOB74_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HCI1221144.1"
                     /translation="MSETVYFFDHLQKLIKRKNTRSLIEVSQEKEISSDKSDLMKDTL
                     YVTTKYDKEIEDARYMAIRENESSFSLYRITKVSDPFETLEFTGLGFATNELDAYIIK
                     DIRPSGQPLKNVLDRLIEFTEGNWRVGHVEAMLPTVTATFYYVSVKEALKELQTLGME
                     FVFRCSLNSDGIKDKWIEVYEQIGEESNTRFVYGSKALTVVREIDRSSISTSMIGRGR
                     GEEVGDGYGRRIEFTDVEWKKSNGDPLDKPKGQNRLEDPESTQKYGIPQKDGSMRKRE
                     TVVVFDDIDDPTDLLKNTYSTLIDSARPLVQFKAEVTGGDVIGNTVTIHRYDKGYHYK
                     TRIYKTTFNRLTGQTNIELGDNLTQDVRKQTASIVNNINSLESSKMTFYESTEIGKYQ
                     DDIMRGAGDNGGSIYWVNGIEAGVSDSREIYETVYMDGPNIPRSRFFMVQNNSGISFK
                     QCKKGEWQTIQDVHNGDSTTAWTLDGTFNANFIRAGILSGILVQGVALKTFDDKDFQL
                     VAEGGELSFEKQVKSTGLDDVHGERLGSIVSTYGSKGINGFAVWKEPNYIFSINAGDG
                     GDRGNPIFQIPADVTADKRKYNLYGDGNFSEGNITIDGRLDVKELYVNGTKIDTNGGG
                     NSGGNDNGWNGQYPPEVTTDRDKRYWQIWATAIGAGFTQQAAAALLGNAQGESDANPT
                     ADEGNGAPGFGYGVWQWTDSSGATSGRVYMINLMTKAGISDDPDTITAQFKLLMWHAP
                     NGQWIATSAYPYTWTQFMNLTDINTAAQAFVANFERPRDPHPERTAWSQEWYDKFKDL
                     EIPVSKGYMKPIADPITVTSEFGWRTSPITGAQEFHNGIDLVNGNPNTPIFASADGEV
                     IVAGDANYFDWYGNWTVIKHADGMYTGYAHQSRVDVSKGQKVTAGQQIGLMGTTGPST
                     GEHLHFQFMDEFYPSSSGHFHNARDYIDF"
     gene            10604..12361
                     /locus_tag="NOB74_001974"
     CDS             10604..12361
                     /locus_tag="NOB74_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HCI1221145.1"
                     /translation="MQETTSISKGGIVMAETQHKMVLSTTEPNNGINLVRIRQGDVLT
                     QKFVVEVVEHGKLKTFEGLVPFFINTTKFGENQPVEQKVQEYSPAQARLVYTLSEPDW
                     QWGGENTAHFSFRSLNGDGTWSEQFSTQDFTYRVISGISRSQLRDSGYVWTFEDLLRK
                     FKDYMDQGKNDWEQWLEDNREILENIDPGGMIINILNEAKGDYESLADRLNQKYQVPV
                     GSSQIRETTRFFDYDTMKYVDLVPRNLNTVVNSVNNSKFNFSFITDIHADNHNLRIDG
                     VGYKDASYLRHWRAIPQFQKLGNKTDVMIYGGDNIDGGLGSLGSDIGIIDEWSARHSM
                     LGTLKRFTNAAVAGQEKPVIICKGNHDACFDPAWRKRKGMLCNADFEEYWNGLYGGVL
                     FPDKNAAIYRFDTCDFYEGGTGDKYVDGYSDTAPGAFSAKQINAFGEWLVNVPRNYHV
                     ALVGHTPLGLSKFPVRNENMISTLIEGFKSGSPVTIDWSKLGQPNDGSFGGLKTFAMN
                     TKGAGVVVGYFCGHWHEQVEGAFGTVKMILCDVGFSHTASQVDTPDELAFYKIEVDTA
                     TRKVTSKGVGRARDFTYNY"
     gene            12378..13160
                     /locus_tag="NOB74_001975"
     CDS             12378..13160
                     /locus_tag="NOB74_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221146.1"
                     /translation="MLDFQSKPNIFEEMSYEEAVKWLLRQAAIHYDGSDHDAHVLATE
                     SNAGFATPETVMQARGRWLRDYKLPQKYPNILDIPPGKYATKAGWGADNPDGIEDDSF
                     VEMMVFADHDSRKLIVAFARYSGEIYIKMTHNSEPVEGYNSLGWRRVYTTSVLFEGEL
                     RKGQSVNLPDDTFRYQTLRIHYTDGDGDFVEEVKRQRYARITKANLWNGDAGVTFIEF
                     ELTIEARKITMSNGRALDISSGNVSNPAMSNNVKITKIEGVK"
     gene            13160..15346
                     /locus_tag="NOB74_001976"
     CDS             13160..15346
                     /locus_tag="NOB74_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HCI1221147.1"
                     /translation="MAHVIKKGSIKVPTQPKDYDLQATGLVFKSYDNQIALEFNVEQQ
                     NGTPADLLGANLRLLMFIYDEVDGMITKEPIPFITKNLITESFLNGQVVYILPEAMKA
                     YNGMVEAYVYIEYPDGSTSDNLGFTFRMKRSAIDGLAQDKADYFIADFQQLLDGVKQE
                     ATDAVNAALTNVDSTIEKANQQINEFVEGATQAIDQTVDEVTEQLQATQTKIDTVSQN
                     VTSAQNNLKAVEDKMNQTNQQIGDLGKLKKMYSNSIDFGNYDYSGNPNLMSKLKSSDF
                     NVGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQLASGKTYTLSAKVRFDEGTTGAI
                     DKLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYMSISFV
                     DRDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWLGKAPLGENIANKSVTFPIKSSA
                     YSLYQANMEEEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWG
                     LTFTPQKVGVNYPKRLTIIQYPQSTTGACQIDWLKIEKGDTRTPNISQFKYFGEGLKD
                     SNNPNDYSWDVTPEYTEKGLNDAVNVYDPQRVEGLKNFADGIQIAGDKVISENDCTVY
                     TLTKDNSQSFIDGYATFIKHGKEVIVNGTVKFKKAYAFGVPLDDEVPDEFVAKIVHGM
                     LTGPSGTSSVSKAMYVRKDLGTIITNSEFAANEWFTFHGNYWVGEE"
     gene            15349..15795
                     /locus_tag="NOB74_001977"
     CDS             15349..15795
                     /locus_tag="NOB74_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221148.1"
                     /translation="MKNIWKYGRTGGEYAGQVLDDMVMTVPFTDVPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLVNVLDHNDLNNLKAMYESLENENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADGLAQINSKTMLASFQNSKDIAEIKEQLNPASKGGE"
     gene            15797..15934
                     /locus_tag="NOB74_001978"
     CDS             15797..15934
                     /locus_tag="NOB74_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HCI1221149.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEAEKIINKDKSA
                     S"
     gene            15971..16264
                     /locus_tag="NOB74_001979"
     CDS             15971..16264
                     /locus_tag="NOB74_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221150.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
     gene            16287..16484
                     /locus_tag="NOB74_001980"
     CDS             16287..16484
                     /locus_tag="NOB74_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCI1221151.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            16495..17514
                     /locus_tag="NOB74_001981"
     CDS             16495..17514
                     /locus_tag="NOB74_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HCI1221152.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            17771..18418
                     /locus_tag="NOB74_001982"
     CDS             17771..18418
                     /locus_tag="NOB74_001982"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI1221153.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
     gene            18701..18774
                     /locus_tag="NOB74_001983"
     tRNA            18701..18774
                     /locus_tag="NOB74_001983"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18735..18737,aa:Ile,seq:cat)
     gene            19320..>19889
                     /locus_tag="NOB74_001984"
     CDS             19320..>19889
                     /locus_tag="NOB74_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HCI1221154.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT         6891 a         3205 c         4266 g         5527 t
ORIGIN      
        1 cttaatgaaa aagaaacaac ttttaccaat gaacttgcaa atgtttgctc aaacatggga
       61 tccagataat gtcttggtat atgaaacgaa agagggaaaa attcctgata aatataatac
      121 gctcattttg agtgaagtta tggaaaattc taagatcatg cagttagcaa aatacgaaga
      181 aatgactgac aaagaaaaga aatttgaata ctttgcagaa ggaccaggcg catactgggt
      241 gggtgaaggt gaaaaaatta aaacgtctaa acctaaatgg atgcaagcta cgatgactgc
      301 aaaaaaactc ggtgtcattc ttccggtttc tcgtgaatat ttaaattata aattatcaga
      361 tttctttgag gagatgcagc caaaaattgc tgaagctttc tataaaaaat ttgatgcagc
      421 tgccttatta aataaagaaa acccatttcc tcagtcacta gacggatcag ttattagtgc
      481 ggggaatgtg gttgaaggcg gattgactta tgataatatc ctagccttag aagacaagtt
      541 agcagaaaat gaattcgaac ctaatgcgtt tatttcaaac cgaaaaaatc gtacagaatt
      601 acgttctgca gctcaaacag tcgggtcaaa tgttgagttt atttatgatc gctctactaa
      661 tacaattgac ggattaccag tagtagacct taagtcttta gataaaggaa cactttacgc
      721 tggagacttt aattacatgt tttatgggat cccatataat atttcattta agatttctga
      781 agaagcccaa ttgtctactt taactaatga agatggaacc ccagttaact tgtttgagca
      841 agaactgatt gctttgcgtg caacaatgga tgttggattt atgattgtaa aagatgaagc
      901 atttgggaag atttccccaa aagcgtaacg cctgctaccg gtattgtgcc aaatcaaaag
      961 acatggaccg gtaaagtagg cgatactaaa acatttacta tttcagctgt gcctgcagat
     1021 gctagcgatg cagctgctgt tgttgcagct actacagcaa cttcaagtga tggagctatc
     1081 gcaacagtga ccaaaaatga aaatggtggt tttgatggaa cgattgcagc agaagggtca
     1141 gcaacattca catttacttc tggagaattc actacttcaa tcaatgtgac aggtcaacct
     1201 gctagttagg aagtaaaaat atgatgattg cagatgatat taaaaaactt cttaaaggaa
     1261 caatagatga aaagcttgaa gttattgagc gaagaacgaa tgagcgtatg aaaaccttgt
     1321 taaatacgca agaagttcct aaagaatttg aaacagttgt atatgaagta tcgttgaaaa
     1381 gattcaatag aattggtcaa gaaggtatgc agtcatattc tcaagaaggt ttatctatgg
     1441 cttttcctga ctcggatttt tcaaagtatc aaaatgagat tgatgaattt aagcgtaaag
     1501 atcaggaaga gttgtacaag ccaaagcgag ggaggtttaa atttgtatga gatttacaga
     1561 tgaaattata tttgttaaac gttcatctga ctctaaatat gatccagatc tcggtgagtg
     1621 ggttgaaggc aaaccagaaa gaacaagaac agaggcaaac gtgacagata ttggcactga
     1681 tagaagtgtg actatttttg gtagtgtgga agaaggggcg aaggtcatta ggacgcagcc
     1741 tcttttttct atccctacat ttgactatat cgagattgaa ggaaagactt ggcaacaaaa
     1801 aacagctaga aatccagcat atagaaatag tttaattgtg caagaggtgg ttcttgatga
     1861 aggcacaact tgaatataaa ggaatcgatc agctgatgcg acatctgaaa aaagcagcaa
     1921 cgcttaatga cgttcaaaaa gtcgtgaaaa gtaatactgc tgaaatgact gaacgaatgc
     1981 aaaaaggtgc gccagtggat acaggttact tacgaagatc aataaacatg aatcttttag
     2041 aagctggttt aactggtatt gtaggaccga cagcagatta tgcaccttat gtagaatatg
     2101 gcactcgatt tatgtcggca cagccttatg ttagaccagc gtttaattac caaaaagtca
     2161 aatttatggc tgaaatgaaa gccttggtga aatgatgatt aagacaagag atcaatcaat
     2221 ttttgatgaa ctttttaaaa tatcccaaaa caaacttgga tataaaacat acgattacaa
     2281 aactttagag gatgttggtt atccttttgt ggaatttgag aacactcaga caatccatga
     2341 agtaaataaa actgacatta aagggtctgt gattgtggtt ttatccgttt ggggattaca
     2401 gaagaaacga aagcagttgt cagatatggc atctgctctt tttaatgaag ctagattgat
     2461 agaagccaca gaaggctatt attgggcttt aaattatcaa gcaagtggaa ttcaagtgat
     2521 ggacgacaca acaacgaata caccgctaaa acgggcggtt gtcacacttg aatttagaat
     2581 tagataggag gaagaacatg gaagcattaa aaggtattga tgtcattttg ctttatcgct
     2641 tattgaaaaa agaaactcag gaagccgctt ggaaaatggc atttcaaaca gaacacgaaa
     2701 atggtttatc aagagattca gactctacag tgacaaaaga tggaaacgtt caaagtttaa
     2761 gcccggttga atatgatttt tcggctactt caatagttgc taaaggagat tctcatgtag
     2821 atgaaatgaa acaagcttta ttaaatgggg atatcattga aatttgggaa attaataaag
     2881 cagaacaggg aacagatgat aatgcaaata agtacaaagc tacttattac caagcatatg
     2941 tgtctgaatt tactccatcg gctgctgcag aggataacgt tgaattaagt ttatcatttg
     3001 cagtaaatgg tgttggtcaa gatggttatg caaccttgac agaagatcaa gccgatgttg
     3061 ttcaatatgc attcaaagat accgtgaaag caacttcgac aggagcataa gagggcttag
     3121 atgctctctt ttttatttta ggaggatgaa aaacattgaa attaaaaatt aaaggtaaag
     3181 aatattcgtt taaatttggc actaaatttg tacgtgaatt agataaagtg atgcctttcg
     3241 tcgatggaaa tatggaattt ggaatgggac tctccgcaaa agtcttacca gagctacgtt
     3301 cttataacgt taacacgtta tcacgagttc tggaaatagc aaatagaact gaagatgaat
     3361 ctattacatt agatgaattg gatgattaca tcgatgaagt taaagacatt gaaaaattgt
     3421 ttgatgaagt cctaaaagaa ttggcggagt cgaacgcggg aaagttagcg gtccgaaacc
     3481 tgaatcagaa attgaaagaa gcggaaaaac aacaagtgga atagattctg cactggcata
     3541 cgaacaaatt cttatcaatt cttttcgata tttgggaatg accaatatct cagatatcga
     3601 aagaatgacg ttatatgaat acaacattcg tatgactgca gcccagttat cttggcttga
     3661 caaagaaaag ttgattcacg aattagcgtg ggcaaatcag caagtccaag cggagaaaaa
     3721 agtaggcaaa aagacagttc ctgtatatcg atcctttgaa gaattcttca attatcaaaa
     3781 aatcgaagat tcaatcatgg gagtttccga actttcaaaa caagataaaa aattccaaag
     3841 cttactaact aaagctaact cttgaggaaa ggaggagaat catggaacaa ttttctgttg
     3901 aagccttatt aaaagccaca gatagtggat ttgtaaagac ttttaaagat gcacaagatg
     3961 ctgttaaaac ttttgaaaag aattcaaata gtatgacaac cgctgttggt aaagtgatgc
     4021 aaggtactgg tgccgcaatg acaaagtata ttaccactcc tcttatagga gtaggcgtag
     4081 cagctgctaa agttggtggc gacttcgaag cacaaatgag tcgtgtaaaa gctatatcag
     4141 gagcaaccgg cgacacattc gaacagatga aacagcaagc gattgatcta ggagcaaaaa
     4201 ctgcttttag cgcaaaagaa tcagctgctg gaatggaaaa cttagcttct gctggattta
     4261 gcgcacaaga aatcatgaaa gcaatgccgg gtcttttaga cttagcagct gtatctggag
     4321 gggatgtggc tctagcttct gaaaatactg ctactgcttt gagaggattt ggtttagaag
     4381 caagtgaagc aggacatgtc gctgatgtat ttgctcgtgc tgctgcggat accaatgctg
     4441 aagttggaga catgggagaa gcattgaagt atgttgctcc tgtagctaat tcaatgggga
     4501 tttctttgga agaaactgca gcagctattg gtattatgag tgacgcaggc attaagggtt
     4561 ctcaagcagg tacaacgttg cgaggagcat tgtctaggtt agcaaggcca acaaaggcta
     4621 tgcaagatac aatggataat ttaggtgttt cgttttatga tgctgacggt aaaatgaaac
     4681 ctttaaaaac tcaagtagaa ttacttaaaa aagcttttga aggcctgacg cctgaacaac
     4741 aacaaaatgc tttagtaaca ctatatgggc aagaatcatt atcagggatg atggctttga
     4801 ttgataaagg acctgattca ttgggcaaat taacaaaatc tctgaaagat tctgatggtg
     4861 cagctgacga tatggctcgg accatgcaag ataatatgaa ttcttccatc gagcaaatgt
     4921 ttggagcttt tgagtcagca gctattgtaa ttcaaaagat tctagcacca tccatcaaaa
     4981 aagtagcaga tgccatatcc ggcttagtag aaaaatttgt aagtgctcca gaatcaactc
     5041 aaaaattagt agtggccata ggagcaattg tcgctgctat aggaccgtta atttttatga
     5101 ttggttcagt aattatatgg atcaataggg tgaaagtagc ttttaaagct ttaagtgaaa
     5161 gttcaaaatt gtttagtgga ttaagtaaag caatgggtct tcttacaaat ccggtttttc
     5221 tggttatagc tgcggtagca ctactcgttg taggtttcat ctatctttgg aatacgagtg
     5281 aagattttag aaacttttgg attggcttat gggagggaat caagtctgct gtaagctcgg
     5341 cagtagaatg gattcagaat gcatggaaat ctacaggaga atggtttaac aatttatgga
     5401 agtccattaa agaaggcgca gacaatgttt ggactacagt tcaagaagcc cctgggaaag
     5461 cggcagattg gattaaaaac aaatggactg gaacaaaaga gttcttttca aatttatggt
     5521 caagtattgc aaactctgct tcagagattt ggaatagttt aaaagaaggt gtcatatcag
     5581 ttattgatga tttagtttca agtgctggtg aaaaatggga agggtttaaa aatactatat
     5641 ctactgcatg gaaaacaatt acaagtaaaa tcaaatctgg ttttgatttt atactaaaat
     5701 atattggtcc atttgtaagt agcttttcag atgtgttctc taatatagtg aaagcaataa
     5761 caagtatatt tgctgaggtt aaaaacataa tagtaaatgc ttgggaaatc attaagtctt
     5821 taatagctgc gccactactg tttattatag atttaattac tggtgacttc gaacaaatga
     5881 aagaggattt agatctaatc tggaacacac ttgtccaatc agtggtaaat atttggacat
     5941 ctgtaaaaaa tatatttacg gaatatatcg gtgcaatagt aaatagtgcc gttagtttat
     6001 ggactggatt catacaaagt atttctaata tttggaatga agtagtttat caagcgacta
     6061 tgatttggat tgatttgaaa ctatttttta ctaatttatg gattgatatt aaatacagtg
     6121 caattcaaat gtggataaat ctaaaattct ccataattca aacttggatt gatacaaaat
     6181 atggtgcaat tgaactttgg aataatctaa aacaatggtt tttccaaacg gttaataata
     6241 tcgtgcaaac tcttataaaa agttggaaca gcttaaagca aggaacgata gatttattca
     6301 acaatacagt tcaaggtgct aaagacattt ggacttcatt caaatcttgg attggtgatt
     6361 taattactgg aaccaaagat aacatcattc agggatggga aaacctaaaa caaggtacta
     6421 tagatacttt caacaattta gtaaatggtg ctcaagaggc atgggataat ttagtaaatg
     6481 ctgttagtga cacggttgat agagtaactg gctggtttga taacttgaaa aatatcgatt
     6541 tactagcagc cggaaaagct atcatggata gttttctaga agggttacaa aatgcatgga
     6601 aatctgtgca agattttgtt ggaggtattg gtgattggat tcgtgaacac aaaggaccta
     6661 tccaatacga tagaaagcta ttgattccag ctggtcaggc tattatgaac ggtctgaata
     6721 aaggtctgac aggaggattc aatgacgtac agaatactgt tggaagtatg gcagacttta
     6781 tcgcggaact tttcaatgca aattctgatg tagatatagc tgcaaatttg aaaaatgcaa
     6841 ataaaaacat tggtgcacaa gttgaacata aaataaatat gggtggctct actaaaccag
     6901 ctgtatttaa aatcaatctt ggaagacaat cgtttagatt gtttatggac gatatttcac
     6961 aagctatggg cgaaggtgca gatattaatc tggaatttta ggagggaata ttttggatca
     7021 acgagaaaat aaaatgtact cattcaaaga tacaaccatt aatctcacta gttctaaacg
     7081 attccttccg acgtctgcca tgatgtacga tggaatgtat ttagaagatt tgattgatgg
     7141 ttatcaaaca cttacggtgg aaggtagaga aatgctttct gtagaagttg aacagcaaga
     7201 gatacaaatt ggttcaatca ttacaaatca gaaaatacct tcaagaacac taaaaataac
     7261 atataagctg gaagatagag atccagaaaa actacagttt aaattcaaag aactgttgaa
     7321 ttatttatac cggaatgaag acgtggaaat taggtttcat gatgaattag attattatta
     7381 ctacggtcgc tatacatcaa ctgatactgt tccaggagac tccaactcga ttatttcgag
     7441 ttttaatgta ttctgtgcgg atccactaaa gtatacgaaa gagtgtgtta gtgatggcta
     7501 tattggaaat ccgatacagt ttcctataac accaagaaaa attgaagtta ctttatccat
     7561 gaataattca atcaaaatta caaacggaga acaaaatatc acgataactg acgcggcaat
     7621 aaaaacagga gacgtgttgg tttttgattt ttccgatgag caggtaactg taaacggaga
     7681 agattgtact tctatgattg atttagaaag tgattttgag aacttttatc ttaagcaagg
     7741 tcagaagata actagcaata atgggaagct taaaatattc tatagggggg cgacaatttg
     7801 agtgagacag tttatttctt tgatcacttg caaaaactta ttaaaagaaa aaatacaaga
     7861 agtttgattg aagtctccca agaaaaagaa attagttctg ataagagtga tctaatgaaa
     7921 gatactcttt acgttacgac aaaatatgat aaagaaatag aggatgcaag atatatggcg
     7981 attcgtgaaa acgagtcgtc tttttcgttg tatcgaatta ctaaagttag cgacccattt
     8041 gaaacattag agtttacagg gttaggattt gcgacaaatg aattagatgc ttacatcatc
     8101 aaagatatta ggccgagtgg gcagccctta aaaaatgttc ttgatcgatt gattgaattt
     8161 actgaaggaa attggcgcgt tggtcacgta gaagcaatgt taccaacagt aactgcaact
     8221 ttttactatg tctctgtaaa agaagcgttg aaagaattgc aaaccttagg tatggaattt
     8281 gtctttaggt gttctttgaa ttctgatgga ataaaggata aatggatcga agtatatgaa
     8341 caaattggcg aagaatcgaa tacacgtttc gtatatggta gtaaagcatt aacagttgta
     8401 agagagatag atagaagctc aatctcaact tcaatgatag gtcgtgggcg aggcgaagag
     8461 gttggtgacg gttacggtag aagaattgaa ttcactgatg ttgaatggaa aaagtcgaat
     8521 ggtgatcctt tagataagcc taaaggccaa aatcggcttg aagatccgga atcaactcaa
     8581 aagtatggga taccacaaaa agatggatca atgagaaaac gagaaaccgt agtagtgttt
     8641 gatgatatag atgatccaac agatttactt aaaaatactt attcaacctt aatcgattct
     8701 gctagaccgt tagtacaatt caaagctgaa gtcactggag gagatgtgat aggaaataca
     8761 gtgactattc acagatacga taaaggttat cactataaaa ctcgtattta taaaactaca
     8821 ttcaatcggc ttaccggtca aacgaatatc gaactagggg ataatttaac acaagatgtt
     8881 agaaaacaaa cggcttctat tgtcaataat attaatagtt tagaatctag caaaatgaca
     8941 ttttacgaat cgacagagat tggaaaatat caagatgaca ttatgcgagg tgcaggagat
     9001 aatggcggtt ctatttattg ggtaaatgga attgaagctg gtgttagtga tagtagagaa
     9061 atctatgaaa ctgtttatat ggatggacct aacattccta gatcacgctt ttttatggtc
     9121 caaaataact cagggatatc tttcaaacaa tgtaaaaaag gtgagtggca aacaattcaa
     9181 gatgtacaca atggtgatag cacgaccgct tggacgttgg atggaacttt caatgctaat
     9241 tttattcgcg caggcattct gtctggtatc ctcgtgcaag gggtagcttt aaaaacattt
     9301 gacgataaag atttccaatt agtggcagag gggggagaac tttcttttga aaaacaagtc
     9361 aagtctactg gactagatga tgtacatgga gaacgcttgg gctcaattgt atctacttat
     9421 ggttctaaag ggattaacgg ctttgctgtc tggaaagagc caaactatat tttttccatt
     9481 aatgctgggg acggtggcga tcgagggaat cctatttttc aaattccagc agatgttact
     9541 gctgataagc gcaaatataa tctttatggt gacggcaatt tttcagaagg aaatataacc
     9601 atagatggac ggctagatgt aaaagaactc tatgttaacg gtacaaaaat tgacactaat
     9661 ggaggaggca attccggagg gaacgataac ggttggaacg gacaataccc accagaagta
     9721 actactgatc gggataaacg atattggcaa atttgggcaa cggcaatagg tgccggtttt
     9781 acacaacaag ctgctgcagc cttacttgga aatgcacaag gagaatcaga tgctaatcca
     9841 accgctgatg agggcaatgg cgcaccaggg ttcggttatg gtgtatggca atggaccgat
     9901 tcttctggcg caactagcgg acgtgtctac atgatcaatt taatgacaaa ggctggcatc
     9961 agtgatgatc cagacacaat cacggcacag tttaaattgt tgatgtggca tgcaccaaat
    10021 ggtcaatgga tcgcaactag cgcttatcct tacacatgga cacaattcat gaatctgacc
    10081 gatatcaaca cagcagcaca agcattcgtg gctaactttg aacgtccacg tgatccacat
    10141 ccagaacgga cggcatggtc acaagaatgg tatgacaagt tcaaagattt ggaaattcct
    10201 gtatcaaaag gatatatgaa gccgattgcg gatccaatca cagtgacgag cgaatttggc
    10261 tggcgcactt ctccaatcac aggagcacaa gaatttcata acggtattga ccttgtaaat
    10321 ggaaatccta atacacctat ttttgcttca gcggatggcg aagtgattgt tgcaggtgat
    10381 gcaaattact ttgactggta tggaaattgg acagtgatta aacacgctga tggaatgtat
    10441 acaggatacg cgcatcaaag ccgagtagac gtctcaaaag gtcagaaggt aactgctggt
    10501 cagcaaattg gactgatggg gacaacagga ccatccactg gagaacatct tcattttcaa
    10561 tttatggatg agttttatcc atcttcttca ggtcatttcc acaatgcaag agactacatc
    10621 gatttctaaa ggagggatag tcatggcaga aacgcagcat aaaatggtcc tatccaccac
    10681 cgaaccaaac aacggaataa atttggttcg aattcggcaa ggggatgttt taacgcaaaa
    10741 gttcgttgtt gaagtggtgg aacatggcaa actaaaaaca ttcgagggcc tagtgccgtt
    10801 ttttattaat acaacaaaat ttggcgaaaa ccaacctgtt gaacaaaaag tacaagaata
    10861 cagtccagcg caagcaaggc ttgtttacac cttaagtgag cctgactggc aatggggtgg
    10921 tgaaaacacc gcacatttca gtttccgatc acttaatggt gatggaactt ggagtgaaca
    10981 atttagcaca caggatttta cctatcgagt catttctgga atatctagaa gccagttacg
    11041 tgactctggc tatgtgtgga catttgagga tttgctaaga aaattcaaag attacatgga
    11101 tcagggcaaa aatgactggg agcagtggtt agaagataat cgtgaaatac tggaaaatat
    11161 cgatccaggt ggtatgatca ttaacattct gaatgaagct aaaggcgact acgaatcatt
    11221 agctgatcgt ttaaaccaaa aataccaagt gccagtcggc agctcacaaa ttagagaaac
    11281 aacacgcttt tttgattacg acacgatgaa atacgttgac ctagtgccgc gcaatttgaa
    11341 tacggttgtc aacagtgtta ataacagcaa atttaacttt tctttcatta cagacattca
    11401 cgcagataat cacaacttgc gtatagatgg cgtcggttac aaagatgctt cttatttaag
    11461 acattggcgc gcaatccctc aatttcaaaa attagggaac aaaacagatg tgatgattta
    11521 cggcggagac aatatcgacg gcggacttgg ttcactcggc agcgatatag gcattattga
    11581 tgaatggagc gcgcgacatt ccatgttagg cacgctcaaa cgcttcacta acgcagcggt
    11641 agcaggacaa gaaaaaccgg ttattatctg caaagggaat cacgacgctt gtttcgaccc
    11701 cgcgtggcgc aagcgaaagg gaatgttatg caacgctgac ttcgaagagt attggaacgg
    11761 tttgtacggt ggcgtgttgt tcccagataa aaacgcagca atttaccgtt tcgatacttg
    11821 tgatttttat gaaggcggca caggcgacaa gtacgtggac ggttacagcg atacagcgcc
    11881 gggagctttc agtgccaaac aaattaacgc tttcggagaa tggttagtga acgttccgag
    11941 aaactatcat gtggcgttag taggacatac gcctttaggt ctcagcaagt ttcccgttcg
    12001 caatgaaaac atgattagca cgttgataga agggtttaaa tctggtagtc cggtaactat
    12061 cgattggtct aaattaggac aaccgaatga cggttcgttc ggcggattaa agaccttcgc
    12121 aatgaataca aaaggcgccg gcgttgtagt aggttatttc tgcgggcatt ggcacgaaca
    12181 agtcgaaggg gcgtttggaa cagtaaaaat gattctttgc gacgtcggct tctctcatac
    12241 agctagccaa gttgatacac cggatgaatt agcgttttat aaaatagaag ttgacacagc
    12301 aacaagaaaa gtgacaagca aaggcgtagg gcgcgcgaga gacttcactt ataactatta
    12361 aggcggtgaa caattaaatg ttagattttc aaagcaaacc aaatattttt gaagaaatga
    12421 gttatgaaga ggctgtgaaa tggttattgc gtcaagcggc tatccattac gacggctcgg
    12481 atcacgacgc gcacgtccta gctactgaaa gcaacgcggg ctttgctaca ccggaaacag
    12541 ttatgcaagc gcgtgggcgt tggttacgcg attataagct accacaaaaa tatccgaaca
    12601 ttttagacat tccgcccggc aaatacgcaa ccaaagccgg atggggcgca gacaaccctg
    12661 acgggattga agatgacagt tttgttgaaa tgatggtatt cgcggatcac gattcgagaa
    12721 aattaatcgt cgcttttgct cgttatagcg gcgaaattta catcaaaatg acacataaca
    12781 gcgaaccggt agagggttat aactcgttag gctggcggcg cgtttacact acttctgttc
    12841 tttttgaagg cgaattaaga aaaggacaat cagtcaatct gccagatgat actttccgtt
    12901 accaaacgct tcgtatccac tacacagacg gtgacggaga ctttgtagaa gaagtgaaac
    12961 gtcaaagata cgcgcgaatt acaaaagcga atttatggaa tggagacgcg ggagtgacgt
    13021 tcatcgaatt tgagctgaca atcgaagcgc gaaagataac gatgtcaaac ggcagagctt
    13081 tagatatttc atccggcaat gtttccaatc ccgcaatgag caacaacgtg aaaataacta
    13141 agattgaagg tgtgaaataa tggcgcatgt catcaaaaaa ggctctatca aagtacctac
    13201 acagccgaaa gactacgatt tgcaagcaac ggggcttgta tttaaatcat acgataatca
    13261 aatagcgtta gagttcaacg tcgaacaaca gaacggcaca ccggcggact tgctaggagc
    13321 taacttgcgc ttgttgatgt ttatctatga tgaagtagat ggaatgatca cgaaagagcc
    13381 aatccctttt atcacgaaaa acctcatcac tgaaagcttc ttgaatggac aggtcgtata
    13441 tatcttgcca gaagcgatga aagcttataa cggtatggtg gaagcttatg tttacatcga
    13501 gtatccagac ggatcaacaa gtgataactt aggcttcacc ttccgtatga agcgttcagc
    13561 aatcgacgga ctagcgcaag ataaagcaga ctactttatt gcagactttc aacaattact
    13621 tgatggagtc aaacaagaag caacagatgc tgttaacgca gcattaacaa atgtggattc
    13681 tacgattgaa aaggcaaacc aacaaataaa tgaatttgta gagggagcca cacaagcaat
    13741 tgatcaaact gttgacgagg taacagagca actacaagct actcaaacta agattgatac
    13801 cgtttctcaa aacgttacat cggcacaaaa caatcttaaa gcagttgaag acaagatgaa
    13861 tcaaaccaat cagcaaatcg gcgacctcgg caagctgaaa aagatgtaca gtaacagcat
    13921 cgacttcggg aattatgatt atagtgggaa tccgaattta atgtccaaac taaaatcgag
    13981 cgattttaac gttggttacc acgggtcact aacttcggat aacgaaaagc tacattttac
    14041 ttctgatggt acaggaagca ttattatgtt tacgcgtatt aatacacctc agcttgctag
    14101 tgggaaaacc tatactctga gtgcgaaagt tcgatttgat gaaggaacta caggagctat
    14161 tgataaatta cgtttggtgt atcgtacatc accaggagaa aagatattat tggaagcaaa
    14221 tagtacaaat attacaacag atgatgtagg gaaagaaata acaatcaaag gtacagctaa
    14281 cgttaattat caaatcacaa atttagatcg attttatatg agtattagct ttgttgacag
    14341 ggataaaata aatggcggat ttaagttgta cgacatcaaa atcgaagaag gctcaacagc
    14401 caccccatat cagccaaact tacttgatga cccttactgg ctaggtaaag cgcctttggg
    14461 tgagaatatt gctaataagt ctgttacgtt tccaatcaaa tctagcgcct acagcctata
    14521 ccaagctaac atggaagaag aatttgtttt aggtcaaacc tatacaatta ccatgaaggc
    14581 aaccaaacca cctatccaaa cgttcattgt ttacaacgag gatagtggag attatagata
    14641 tggtaactta gagccagtag aagggttagt tgatacatgg ggtctgactt ttacaccgca
    14701 gaaggttgga gttaactacc ccaaacggtt aactattatc cagtatcccc aatcaacaac
    14761 aggtgcatgt caaattgact ggctcaagat cgaaaaaggc gacacacgaa ccccgaatat
    14821 tagtcagttt aaatactttg gtgaaggctt gaaagacagt aacaatccca atgattacag
    14881 ttgggatgtc acacctgaat atactgaaaa aggcttgaat gatgctgtta atgtgtatga
    14941 tcctcagaga gttgaaggtt tgaaaaactt tgccgatggt attcaaatag caggagataa
    15001 agtgatcagt gaaaatgatt gcactgttta tacattaact aaagacaaca gtcaatcgtt
    15061 tatcgatggg tatgcaacat ttattaaaca cggaaaagaa gttattgtaa atggtacagt
    15121 aaagttcaaa aaagcttatg cttttggtgt accacttgat gatgaagtcc cagatgaatt
    15181 tgtcgcaaaa attgttcatg gcatgcttac aggtccgtca ggaacaagta gtgtatcaaa
    15241 agcgatgtac gtgcgaaaag acttaggaac aattattacg aatagcgaat ttgctgcaaa
    15301 tgaatggttt acattccatg gtaattattg ggtaggggag gaataaaaat gaaaaatatt
    15361 tggaaatacg gacgaacagg tggagagtat gctggacaag tgcttgatga tatggttatg
    15421 actgttccat ttaccgatgt tccaccactc gaaggaattc gtgctgatgg ggaaccacta
    15481 acgattgctg atcagatgtt tgatcctaaa ctgaaccaat ggattgtttt agtgaatgta
    15541 ctagatcaca acgatttaaa caatctcaaa gcgatgtatg agtcgttaga aaatgagaac
    15601 ggcgatttaa aacagctcaa cgccaaactc atgctaagcg atgtagcgat taaacaggaa
    15661 aatactgcat tgaaagaaaa agcggatggt ttagcacaaa tcaattcaaa aacgatgctt
    15721 gcttcgttcc aaaatagcaa agacattgca gaaattaaag agcaactaaa tccagcttca
    15781 aagggaggtg agtagtatgt ttagttttag cgatgtgaaa atgatgtatg attggggctg
    15841 ttttactgac gatcaagttc gactattcgt tccactatgc attacagacg aagaagcaga
    15901 aaaaatcatt aataaagata agagcgcatc ttaagtgatg cgtttttatt taaggtaaag
    15961 gagttgtcac atgattaatt taggagaatg gggaacaatc gcaggatcaa tcactgcgat
    16021 tgtttctttg attttattag taataagacc agtcactgca tctttctcga agattactga
    16081 aactctttca aaagtaagtc acaatttaga tttgctgact aaagatttag aatcgagcaa
    16141 atcagatcga ttgatgattc atgaagaact aaagaaacac gatgaaagat tagatacaca
    16201 tacagaaaaa ttggtagaac acacacaaca aatcaaaact ttatttagag aaagatctcg
    16261 gtaaaaaaga aaggagttaa gaagaaatga ttttacccga taagtattat caagtcatta
    16321 aatggacagt tttaacagta ttgccagctg catctgtatt agttgcaaca ctaggcaaag
    16381 cgtatggatg gaatggaaca gatatgacag tactcactat caatgcagta gcaacatttt
    16441 taggcgttat cactggcgtg tcggcttata atttgaaaaa ataggaggaa acaaatgaaa
    16501 aagaaaatta ctattactgc gatgagccta ttaacggctc tttttttatt gccaattaat
    16561 gggtttgcct atacgattaa caatgaattt aatttaggcc caaacgaagg tagctcacaa
    16621 gtagcaaata atcagtacat tttactgcat gaaacggcta atgaaacagc aacaggacgc
    16681 aatgaagcgc agtatatgca acgttcatgg actagcgctt atactgctta tattgtggga
    16741 gacggcggaa ttgtttatca agtcggtcaa cctggttatg tacagtacgg tgctggttcg
    16801 tatgctaatg caaatagtcc tgtgcagatt gagttacaac acacacatga taaagcaacg
    16861 tttgagaaaa actacaaggc atacgttgaa ttagctagag attcagcaat gaaatatggt
    16921 attccactta cactagacac accgtataat caaccaggga tcaaatcgca tttatgggta
    16981 acacaaaata tttggggcga tcatacagat ccttacggtt atctttctga aatgggcgta
    17041 agtaaagaaa aattagccta tgatttggct catggattta ccgatgaaaa tccgacaact
    17101 tcagatgata aaccagtcat tgatccaact cgagcaggtg ctgcaaatcc taccctgaca
    17161 gatggaacaa attacgccca cattgatcag ttcggagaaa tcgaaaacgc aaacttacat
    17221 gtggctggtt ggcacatcgc taactataaa tacgagtata tcttcattat ggattacaat
    17281 actgggaaag aattagctcg agtaaaagct gatggaatat atagaccaga tgtaaatcaa
    17341 gcttataata ctttaggaaa tgttggctat catgtatctt ttaacatgcg caacttccct
    17401 aataagaaag tctatgtaat gatgcgggca acgaatgatc cagaagggaa cactaaaggc
    17461 ggagcacaag attttcatga taaacgctgg tatttaaata ttccgcaacg ataaaaatag
    17521 cccctcgttt ttgaggggaa gtacataatg caaatttgtc cataacttat tgattatctt
    17581 gtaaaaatgc ggtaatttaa tagttagtga gaagaggtgc ttaattatag ttaaaaaaga
    17641 ggaaatagaa gcagcatgta accaagcaaa tgttaggttt attggagaag ctttatctgg
    17701 atatcctaag tataaatact tacacaactg gttacaaagt aaaagttttt atcttaataa
    17761 agaaagatgc atgcctaata aaaattatag ggtttataaa agaggaacta ttgtatatgt
    17821 tgattttggg gtgaacgtgg gttatgagtt atctggtaat cattttgcta ttgttttaaa
    17881 taataaagat aattcgaaaa atggtgttgt atgtgtagta ccaatctctt caaaaaagaa
    17941 aagtaattat gtatctgtag gaaaaatatt agaagttgct agtattaaac aatttataag
    18001 ccaagctgat aaattaaaag agaaacttag gataattatt ttactttcat taaatagagg
    18061 catcattgat gaaagcgatt tgaatagttt tattaaagat attgaagcta aaggtgaaaa
    18121 gctttcagtg gaagaagtag aaaaacgagc tgtaaaacat aatttggttt gcgagacaag
    18181 ggaacaagta attaaagaaa taaaatcatt atctgaagat atggtaaaat atcagaaggt
    18241 gtttaattgc tacaagaaat atacacaaga atcctatgta atgccactta atatccaaac
    18301 gattagtaaa aatagaatta gaagaattaa caagtttgat ccttctggaa atatgaaggc
    18361 acctggaaat gtcctcaatg aagtagatga aagtttaaaa aaatatttta caaagtaaac
    18421 gatatttttg ttgacatttt tctgttcgtt agttaccatg tagttataga aggacgtaag
    18481 cgcctatttt taatgtacac atcgggacgt atgcgcccac atagaaacat agttgagaga
    18541 catctatatg gtgtctcttt ttttattaat atgcaaaaaa gtctagtttt ttcaataata
    18601 tttatgtaat aataaattag ccaccacaac aaagaatgaa acccattatt atctagtcta
    18661 tgtccattct ttttgtttgc agtagttgtg atggctttcc gtactcttag ctcagttggt
    18721 tagagcagac ggctcataac cgtccggtcg taggctcgag tcctacaggg tacatactct
    18781 aagtgattta aattgcgaat aaaatataaa aatgactccc cttttgactc ccccaagcag
    18841 tatatggatg tctctaaaag ttgttttttt agataataaa aagctgataa taagcgaaaa
    18901 acacttaaaa tcagctttaa accctattct cgaaatccgg cgaaccggct aataccggcg
    18961 cgcaggttca aatcctgtac cttccttata tcaacgatta gaggttgtga agaagctgtc
    19021 ctgcatcaag taataagaac ggccaaacaa aaatagcttt tcctattttt tcgtttgatt
    19081 gggcttatta ccgcagatgc aagcttttga acaccgtttg ttcggaataa ggggctgtga
    19141 caagactttt gtcacagccc cttattgttg tacttttaac ctacaatatt ttttgattcc
    19201 ccctgagtac tattttttat aaatgctagt aaatcaatct tctttggcct ttttttgata
    19261 aaaaaaatac tagatgtaag ataaaagtgt aaaaacgatt tgttttagga ggggaaacga
    19321 tgtgtaccgc aatcacttat gcaacgaaag accattattt tggaaggaat tttgattatg
    19381 agatgtctta taatgaagtg gtcactatta ctccaagaaa ttatcgtttc gattttagaa
    19441 aggtaaaaaa tttagataaa cattatgcaa tgataggaat agcagctggg gtatccaact
    19501 atccactcta ttatgaggct acaaatgaaa aagggttgag tatggcagga ctgaattttc
    19561 ctggcaatgc tgattataaa gaattacaag aaggaaaaga taacgttgca ccatttgagt
    19621 ttattccatg gatactaggg caatgctcaa ccatagacga agctaaagaa ttattggcta
    19681 ctatcaatct agtcaatatc gattttagtg aaaaactacc cttgtcacct ttacactggt
    19741 tattagctga taaagaaaaa tcgatagtaa ttgaaagtat gaaagatgga cttcatttat
    19801 atgataatcc tgtcggtgtg ttgacaaata atccgccatt tgattatcaa ttatttaatc
    19861 tgaacaatta tcgctcgcta tcaaatgga
//
LOCUS       DAIGWC010000055        19507 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.056, whole genome shotgun sequence.
ACCESSION   DAIGWC010000055 DAIGWC010000000
VERSION     DAIGWC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.056"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="NOB74_001985"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="NOB74_001985"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HCI1221155.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="NOB74_001986"
     CDS             complement(1173..1868)
                     /locus_tag="NOB74_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HCI1221156.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="NOB74_001987"
     CDS             complement(1881..2597)
                     /locus_tag="NOB74_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HCI1221157.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="NOB74_001988"
     CDS             2927..3532
                     /locus_tag="NOB74_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HCI1221158.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="NOB74_001989"
     CDS             3857..4180
                     /locus_tag="NOB74_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HCI1221159.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="NOB74_001990"
     CDS             4362..5732
                     /locus_tag="NOB74_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCI1221160.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="NOB74_001991"
     CDS             complement(5862..7163)
                     /locus_tag="NOB74_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCI1221161.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9351)
                     /locus_tag="NOB74_001992"
     CDS             complement(7393..9351)
                     /locus_tag="NOB74_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HCI1221162.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="NOB74_001993"
     CDS             complement(9528..9794)
                     /locus_tag="NOB74_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI1221163.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="NOB74_001994"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="NOB74_001994"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HCI1221164.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="NOB74_001995"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="NOB74_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HCI1221165.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /locus_tag="NOB74_001996"
     CDS             13138..13701
                     /locus_tag="NOB74_001996"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCI1221166.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="NOB74_001997"
     CDS             complement(13954..14475)
                     /locus_tag="NOB74_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HCI1221167.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="NOB74_001998"
     CDS             complement(14478..15320)
                     /locus_tag="NOB74_001998"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HCI1221168.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="NOB74_001999"
     CDS             complement(15313..16038)
                     /locus_tag="NOB74_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HCI1221169.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="NOB74_002000"
     CDS             16214..16510
                     /locus_tag="NOB74_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221170.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17078..18670
                     /locus_tag="NOB74_002001"
     CDS             17078..18670
                     /locus_tag="NOB74_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI1221171.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="NOB74_002002"
     CDS             18683..19423
                     /locus_tag="NOB74_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI1221172.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5580 a         4002 c         3702 g         6223 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaa
//
LOCUS       DAIGWC010000056        19098 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.057, whole genome shotgun sequence.
ACCESSION   DAIGWC010000056 DAIGWC010000000
VERSION     DAIGWC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19098
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.057"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(224..454)
                     /locus_tag="NOB74_002003"
     CDS             complement(224..454)
                     /locus_tag="NOB74_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221173.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(890..1456)
                     /locus_tag="NOB74_002004"
     CDS             complement(890..1456)
                     /locus_tag="NOB74_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI1221174.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1456..2412)
                     /locus_tag="NOB74_002005"
     CDS             complement(1456..2412)
                     /locus_tag="NOB74_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HCI1221175.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2412..3068)
                     /locus_tag="NOB74_002006"
     CDS             complement(2412..3068)
                     /locus_tag="NOB74_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCI1221176.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3438..5456
                     /locus_tag="NOB74_002007"
     CDS             3438..5456
                     /locus_tag="NOB74_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI1221177.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5526..5732
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5883..8297
                     /locus_tag="NOB74_002008"
     CDS             5883..8297
                     /locus_tag="NOB74_002008"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HCI1221178.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8645..10198
                     /locus_tag="NOB74_002009"
     CDS             8645..10198
                     /locus_tag="NOB74_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCI1221179.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10579..12363)
                     /locus_tag="NOB74_002010"
     CDS             complement(10579..12363)
                     /locus_tag="NOB74_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221180.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12378..14099)
                     /locus_tag="NOB74_002011"
     CDS             complement(12378..14099)
                     /locus_tag="NOB74_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221181.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            14199..14960
                     /locus_tag="NOB74_002012"
     CDS             14199..14960
                     /locus_tag="NOB74_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI1221182.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15927..16195
                     /locus_tag="NOB74_002013"
                     /pseudo
     CDS             15927..16195
                     /locus_tag="NOB74_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16867..>19098
                     /locus_tag="NOB74_002014"
     CDS             16867..>19098
                     /locus_tag="NOB74_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221183.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6282 a         3389 c         3810 g         5617 t
ORIGIN      
        1 tcagtcacga tatcaaacaa aaaatatacg tctttcttca ttctagtttt cgcagcaggg
       61 attttaaagt agttcttatt agaatagtag agattaatta ataagctatc ttcgattgct
      121 aaaaagaaaa cttctgaatc ccacacctta taaaaatctt tgacaaatct attcgaagga
      181 tcaaatttaa accataattg cgtctcatta aaaagcataa ccattactcc gatctatttt
      241 taaacttagt ctctacctct aatatatatc gagtttttat tttgccttca gagaatactg
      301 tttctttttt tgcagttaca ggttgtttat tttcggaaaa agctaatata gctaaaattg
      361 aaacatccat ctggaattta tcttttttac tgctttgatc ataaaagtct gcatattcat
      421 cactgatatt ttttctaata aattcttcca tcataaaaat cacctcaaaa cgattatacg
      481 aacttacgtt cttgttgtaa agcgatattt gaggggcaaa aaaggggcat aatttgactg
      541 atattaagtt agctattgat atatgaatga catacaaaaa tataaaatct tttaaaaatg
      601 cttatatatc aatgtttttg ccattctttt atatatctgt tatatgtcaa aaaaatgtgt
      661 tcaatttcaa tttgtatttg aataaagagg ttgtgaaaaa gctgtcctgc atcaagtaat
      721 aagaacagcc aatcaaaaac agcttctcat gtttttgatt tggttggact tattaccgca
      781 gatataagct tttgagcacc gtgaataaag aggttatgaa atcaacgctc taacctgagt
      841 attagagaaa aaaacgcaaa acatatcatt tatgttttgc gttttttatt tatctttttt
      901 tctcaataca atataaaata ggcggctggt tcttttggtt gataaaccga taattcagca
      961 cattatatgt ttcctgtggc agtttggaac aaaaagaatc aaccatatcc agttcttttt
     1021 ctccaccttc atgaccatag tagacgacaa ggatcaatcg tccgcgaggc acaagtcgtt
     1081 tcaatatttc ttccatagct gtgcgtgtag tctctggcat agtgatgatt gctttatcac
     1141 tttttgggag ataccctaga ttgaaaatcc ctgctttgag attttgttgt tcagctatca
     1201 cttctcctaa cgtttcgtgg ccttgtagaa acaatgagac acgttcttct aactgacgct
     1261 gttctagcct ttcacgagta gcatcgattg cttgttgctg gatatcaaaa ctatagacat
     1321 gaccagtttt tccgatgtgt tctgctagaa aaaccgtatc gtggccattg cccatcgttg
     1381 catctacgac gtgatcccct ggttgcaaga tttcttgcag taatgtatgg ctgaaatgca
     1441 aagcagtttg caacatcaga cgctcacctt tttccgtaca tcatattttc cttggaagct
     1501 atctctgcga agaagttctt catcaattgc attcaagact tcccattttt tcaagctcca
     1561 cattggtcca atcaaggaat cccacggcgc atcccctgtc aaacgatgga tgatgatctc
     1621 ttttggtatc atttccagct ggtcgcaaat gacattgaca tagtcaggac ggctcattaa
     1681 ttgaaggcga ccttcatgat agtcccgcaa cattctcgtt ttgcgcatca gatgcatcaa
     1741 atggagcttg attccttgga tatctgaatc taaaatggtg cgtctgacat tttctttcat
     1801 catttctaaa ctttcgcctg gtaatccgtt gatcaaatgc gtacaaacac ggatattatg
     1861 tttgcgtaat ttagccacgc catctaaata agtttgataa tcatgtgctc ggttgatcag
     1921 ttttgaagtt tcttcaaaag ttgtttgcaa tccaagttct acccataaat acatccgctc
     1981 gttcagttca gcaaggtaat caactacttc atctggcaga caatccggtc gtgtaccgac
     2041 tgataatcct acgacacctg gtaaattgac tacttgctca aatcgttctt tgattatttc
     2101 aactggcgca tgggtgtttg taaaattttg gaaataaacg atgtattgtt ggacatgagg
     2161 ccatttttga tgcatcatgt cgatttcttt ctggaattgg attggaagag ggtcttcagg
     2221 tgcaacgatc atgtctcccg aaccagatac actgcaaaaa gtacaaccgc catgggcaac
     2281 agtcccatct cgattcggac agtcaaatcc tccatcgatc ggcaccttga aaattttccc
     2341 gccaaactca tttcgtaaag cgtaattcca agaatgatat cttttatttc cttctgaata
     2401 aggaaaagtc attaaaagtc cttctttctg taagagttat ctatttgttt tcttttttct
     2461 ctatacactg gataagtcag gcacagccaa gaaagactga gtaagtagcc gccgatgata
     2521 tcagtaggaa aatgaacgcc cagataaatg cggcttatcc cgacacttac tataataaac
     2581 atcatcagca attgaagcaa tgtgcgtaag gttctttttt gaacaaaagc tggaagcaga
     2641 aatagtaaag aaccgtaaag aatcatactg cctgctgcat gtccactagg gaaactgtaa
     2701 cttgtttcaa ctactaagtg cgccaatgaa ggacgctctc gcatgaaaaa tagtttgatc
     2761 accgggttga tgattccagc aattacaata aatccagaaa cgaaccaaaa tgtttctgcc
     2821 ctttttttct tataccacat ccataaagcc gcacaagcaa ataaaatgat gacggtaaga
     2881 ggattaccga atttagtcat aaagagttgg tagctgttca gatcaggata agaagctctg
     2941 acaatgcctg taaaccactg atcgaaacca gaaagccacg acagatggaa ctttacgatc
     3001 cagcccaaaa tgaaaaacag gacaagaaag aagctaccag ccacctgaaa tgatgtttta
     3061 tatttcatac aattcctcct ttgaagcaat gacttattat agcatttttg gtccagcgaa
     3121 aaaaacggta aagagataaa accaatgtat gattcctctt tgaataacca atattcttat
     3181 aaaaaaaata actgtaatcg gaaagacatt ttttggtaat gcaaatgaaa tgttagggaa
     3241 ataaaatcag tgtttttcga aatcctttta aacaagaacg tagacgtagg aagaacttga
     3301 aaatgaacag aagttgttca ttacggtaaa ttacaatatg attacaaaaa acaacaaagc
     3361 tcttaaataa cttttaataa atattaagag aagttataat tattaataat agataaattg
     3421 aagttggagg atagaagatg gaaaacattg caagaaaaga acggagacgt ttagaacaga
     3481 ccaaacgttt tcgaaaagca aaacgagggg cagcaatcgt gggaactgcg atggtaggct
     3541 gttctgtcgc tgccccatta gtacagccgg ttcctgttca agcggatgaa acacctgttc
     3601 agttcggcgc aagaatcaat acagcggcat ttatcacaga aattgctact tatgctcaac
     3661 caatcgctca agccaacgat ctatatgcat cagtgatgat cgcacaagca gttgtagaaa
     3721 gcggttgggg cagtagtgcg ttatctcaag caccttatta taatcttttt gggataaaag
     3781 gcagctatca aggacaaacc gtctacatgg atacgcttga atttttaaat aatcaatggg
     3841 taaataaaaa ggagcctttc cgacaatatc cttcttttgc tgaatctttc aatgacaatg
     3901 cctatgtact tagaaatact tcatttggca acggttatta ctatgccggt acttggaaga
     3961 gcaacacgaa atcctataca gatgcgacag cttgtttgac agggcgttat gcgactgatc
     4021 ctggttacgc aggcaaatta aataatatca tcgcaactta cggattgacc caatatgata
     4081 caccagctag cggaaacgca ggcggtggag cgactacagg tggcaataat actggaagtg
     4141 caggtagtac tggcggttca agcaattctg gtaatacaaa ctcaggttca gcaacttcga
     4201 ccacttatac tgtccaatct ggtgattctg tttggggaat ctcaaataaa ttcggtatca
     4261 caatggatca attgatccaa tggaacaaca tccaaaacaa tttcatttat ccaggacaaa
     4321 aactgacaat caaaggtagc caggaaaatg gctcttcgac gaataattcc ggtaacaata
     4381 ccaactcttc aggaaatgct ggtacatcaa acggaggaca aacaactggt gcgaaataca
     4441 ctgttcaatc tggtgattct gtttggaaga tctcaaatga tcacggaatt acgatggctc
     4501 aattgattga atggaacaat atcaagaaca atttcgttta tccaggacaa cagctaatcg
     4561 tatcaaatgg cggttcttct aatgctggag caaatactgg ctcaaatact gggaatacaa
     4621 gtggctctag ttcgtccagc tcaagttctt ctaatacagc ttcaggaacg aaatatacag
     4681 ttaaagccgg agactctgtt tggagcgtct caaataaata cggaattacg atggctcagc
     4741 taatccaatg gaacaatatc caaaataact ttatctaccc aggacaacaa ctgactgttt
     4801 caaacagtgg atcaacaaac agcacgtcag gtaatacagg ttcgtcaacc aatacaaata
     4861 acagcagttc agttaatact ggcagcagtt cgtctcaagg cacttatacc gtgaaagcag
     4921 gtgaatctgt ttggagcgtg gcaaataaaa acggcatcac gatggatcag ttaatcgaat
     4981 ggaataatat caaaaacaac ttcatttatc caggacagca attgatcgtt aaaggtggaa
     5041 cttcggcaaa tacaaataca ggttcaacta cttctgcagc gaaaccaaat acaccgaata
     5101 cgtctgctac gacaagtaca tcatccactg gtaatacgat gtataccgtg aaagcgggcg
     5161 agtcagtttg gagcgtagcg aacaaacatc atatcacgat ggatcagtta atcgaatgga
     5221 ataatatcaa aaataatttc atctatccag gacagcaagt gattgtgaag aaaggttcat
     5281 ctcaatcaac aaaccaacaa tcagttactg gttcgaaaac ctatactgtg aaatctggag
     5341 aatctgtttg gagtgttgct gacagtcatg gaattacaat ggctcaacta atcgaatgga
     5401 acaatattaa gaacaacttt atttatccag gtcaaacgtt gattgtagct aaataaaata
     5461 gctgttcgaa gaaataacga ttgaattcca caaaaatatt tgttactata aggctactta
     5521 aatatgacaa cacttgaaaa ggaagtagta aaaagactga agtttcagag agcgcatggc
     5581 tggtgagaat gtgcacggat gcttttgaac tcgcctttga gttgcccttg ctgaataccc
     5641 gagtaagcaa gcggcggtga cggccgttac aacgttcgag gccttttcac taaggtaaaa
     5701 ttaggtggta ccgcgtagat tacgtcctat aaaaagagca atctttttat aggatttttt
     5761 tatttctttt gtgaagtttg agaaaacaaa gcaaaaggaa ataaaaataa acagattctg
     5821 ccggtttttt cgttatattt ataatagaaa caagtgtttt caatagaaca ggaggacagc
     5881 aaatgagtta caatcataaa gaaattgaga aaaaatggca aaaatactgg gcaaaaacga
     5941 atactttcaa cacccatgat gatcctgaaa agccaaaatt ttacgcactg gatatgtttc
     6001 cctatccatc cggtcaaggg ctacatgtag ggcatcctga aggttatacg gcaacggata
     6061 tcctttcacg tgtgaaaaga agtcaaggat acaacgtgct gcatccaatg gggtgggatg
     6121 cattcggtct gcctgctgaa caatatgcgc tagatacagg aaacgatcca gctgagttta
     6181 cccaaaaaaa tatcgaaaca ttccgacgcc aaatcaattc tttaggattt agttatgact
     6241 ggaatcgcga agtgaataca actgatccgg agtattataa atggacacaa tggatcttta
     6301 cgaagcttta tgaaaaaggt ctagcttatg aagcagaagt agcggtaaac tgggtacctg
     6361 aattaggaac agttatttca aatgaagaag tgatcgatgg gaaaagtgaa cgtggtggct
     6421 atgatgtagt cagaaaacca atgcgccaat ggatgctgaa aatcactgct tatgctgatc
     6481 gcttattgga tgatctagaa ttagttgatt ggccagaaag cattaaagaa atgcaaagaa
     6541 attggatcgg tcgttcagta ggagcaaata ttgaatttaa agtggctggt acggataaat
     6601 cctataccgt atttacgaca cgaccagata ctctattcgg tgcaacttac tcggttcttg
     6661 cacctgaact agatcttgtt agagaaatta cgacccctga acaaaaagct gctgtagaag
     6721 cttatatcga agagacagct aaaaaatcag atctaaagag aacggatctt gcaaaagaaa
     6781 aaacaggagt atttactggt gcttatgcaa tcaatccagt taatggcaag gaaatcccaa
     6841 tctggatcgc cgattatgta ttatcttcat acggcacagg agccatcatg gctgttccag
     6901 cacatgatga acgtgacttt gaattcgctc aaactttcgg actagaaatt cttccagtta
     6961 tcgaaggtgg agatgttgaa aaagctgctt acacagaaga tggtacgcac atcaactctg
     7021 aatttctaga cggcatgaac aaacaagaag caatcgataa aatgaatgaa tggctagaag
     7081 aaaatggcgt agggaaaaaa gaagtcagct atcgcttacg tgactggcta ttctcccgtc
     7141 aacgttactg gggtgaacca atcccaatca tccattggga ggacggaaca gtcacagctg
     7201 tcccagaaga agagctacca ttacggttgc ctaagacaaa aaacatcaag ccaagcggta
     7261 ctggagaatc tccattagca aatatcgagg agtgggtcaa tgtcgttgat cctgtaacag
     7321 gtaaaaaagg ccgtcgcgaa acgaatacaa tgccacaatg ggcaggaagc tcatggtatt
     7381 acctgcgtta tatcgaccct cataacaaaa aagaactagc agattatgaa aagttgaagc
     7441 gttggctacc agttgacatc tacattggtg gagcagaaca tgcggtactt catttactat
     7501 atgcacgatt ctggcataaa ttcttatacg atatcggtgt tgttcctaca aaagaaccat
     7561 tccaaaaact atacaatcaa ggaatgatct taggcgaaaa caacgaaaaa atgtcaaaat
     7621 ctcgtggtaa tgtagtcaat cctgatgatg tggtcgaaac ttacggtgca gatacactgc
     7681 gcatgtacga aatgttcatg gggccattag atgcttcgat tgcttggagc gaaaatggct
     7741 tagaaggaag ccgtaaattc ttggatcgtg tatggcgttt gatcgttgat gagaacaata
     7801 aaatgcgtga ccgtatcact acattgaatg atggcaagct tgataaagtg tatcatcaaa
     7861 cagtgaaaaa agtgacagaa gactatgaaa atcttcattt caatacagca atctcccaat
     7921 tgatggtctt tatcaatgaa gcctataaag tggacgctct gccttatgaa tatatcgaag
     7981 gatttgttca actactcgca ccgattgctc ctcacatggg tgaagaacta tgggcaatcc
     8041 ttggaaatga tggtggtatt tcttacgcac catggccaac atacgatgaa gcagcacttg
     8101 ttgaagacga agtagaagtt gttttccaag taaacggtaa agttcgtgcg aaaagcaatg
     8161 ttccccgaga cttaggaaaa gatgagctag aaaaagcagc attagccaat gaaatagtgc
     8221 aagaatatat tgaaggcaaa acagtcagaa aagttattgc ggtaccaaac aagttagtca
     8281 atatcgttgc taattaattg gctctttgtc aataaggact gatgagttgt gcaaaatcaa
     8341 atctgggcca gaatgaactt cattctgtct cagatttttt gttatttcaa attgattaat
     8401 tgattgatca aaaaggtttt gattttcatg ttctcaaaca cgttcaatgt ctttttcttc
     8461 tgaatggtct tgtaagagat ctctgtaatc atcaaatttt tgtctattaa tcttagtatt
     8521 ttttgatgta taaactacct gaaattgaga gtacatacca aattcataaa ttttttatta
     8581 gtgggactag tgattgtatg gattttgacg cataatgaat gaagtatgag aaaaggagag
     8641 acaaatggat caagaactat ttattatcga agtattatca gctaaacaaa aaattatcga
     8701 gaaagcgaaa aaaagagcga aaagaataat gttcaagctt ttaagcttag tatttttctc
     8761 tggtttgctt tttttcggag ctgtatcgtt cctatatcgc catatgagtg cagtagtccg
     8821 ttcagctgaa gggatgcaaa aattaaataa tttgtatcac ttttcgtggg gagttggcgg
     8881 aataacaatt gttgtgctta ttgtttttct tctacttatt tggctccgtt accatcaatt
     8941 gtcgcgtcat ttcgatcaat ggcttagtca aagagcacaa cagtttttac ataataaacc
     9001 aacttctcaa gatgatgact atctttattt tgagaagact tcgacgagtc aagcttttcg
     9061 gatacaaaaa agtgattgcc agttattgct gagatcactt gatgatttac ctatctactt
     9121 aggcgaaagc aaatcaaaat tcggaatgaa cacattccat atttttttac tagaaaacga
     9181 acccagatgg gaaaaaagcc agtcttcgcc tggtggatac ctgacaacta agatgagtac
     9241 attagtcact ggttttttcc tcattctttt agctggaaca atctattatg ggagatacac
     9301 tcagccaaaa atgtcttctc atataaatgc tgcttctcac atgacaatga actcaactaa
     9361 cgatacgcat atacaaaaga caaatgaagg gttgttagct gatcctaagc aaaaggtaaa
     9421 tttgacaaca caaaagataa atgatctcaa acttgataca gagacgcact ctctctatat
     9481 gacaacagat agtggtgcta attgggtatt tgtgccgatt gattcgcaat ggttgcgttt
     9541 tggcgaatac accctgacaa cggggctgat tcctgaaggt tattggatgg acaacacata
     9601 tgatatttcc gccgatttct catggtttat ctattcttct ggggatgatg tacgtctgct
     9661 gacttcaaga gataatggta aaacatggca aacgtctatt atcacccaat cagttcagcc
     9721 gatacgttat cgaaaagcgg tattttatgg caacgatggt ctatttatct gtacatcagc
     9781 cagtgggatg tctgcagaaa ctttgtacat ttacactact atggatggcg gaatcacttg
     9841 gataaaaagt ggaagtacaa tgatcaatca gccagtacaa aatgtcagct tcgttacaac
     9901 ttctttaggt tttgtttcga cacgtgaaag tttgttttat acaaacaacg gaggacgctc
     9961 attcaaagaa tcagttctgt cgattccgga aaactatcag acagggggga tagatctttt
    10021 tcaatcacca aatgaagtta ctcaaataag cgcgaatacg ttagagacaa aattttattt
    10081 gttgaaaaaa ggaccaatcg atgcagggaa aatgtttgcc tgcctcttcc gttcaactga
    10141 taacggggaa acatggcaat tcgttcagca actatcgcaa gtagaacaag gagattaaag
    10201 aagagagatt gtgagcctga cgttcagcac cgagtcacaa gaaacaaatt caaaaaacag
    10261 cttctcatat ttgttgaata gtgtaactcg tgattcggag ttgacaagag caacaagaag
    10321 cgattttgaa gtatagcttc tcgtatttta caagatcgtg tcttattgcc gataggttgt
    10381 ctcttgaaca ccgtttattc gtaaaaaggg attgtgacaa gtcttttgtc actacttacc
    10441 gaacgaaact gaaggagcta tccaaaaagt atcattagta ttattctttg tgtttctagt
    10501 ggcaccacta gtacatttaa aaaagctatc gatcatggac taatcataca tgatcgatag
    10561 ctttttagat aatgtttgtt acgctatctg aaattgacta ttataaagac tggcataaag
    10621 cgttggtgat tggagtagtt cagaatgtgt tcctttttcg acgatatcgc cattcttcat
    10681 tacaaggatc atgtctgcat tttcaatcgt tgacaaacgg tgtgcaatca caaaacttgt
    10741 cctatctttt gtcacagctt ccattgcttg ctgaatcaat gcttctgttc gtgtatctac
    10801 gctagaagtt gcttcatcta aaataacgac aggaggattc gctagaatga ctcgagcaat
    10861 tgtcaataat tgttgctgtc cttgagataa cgtgccgttt tcgctagaaa tgatcgtatc
    10921 atatccgtct ggcagtgttc gaataaagtg atcacattgt gcgatttcag ccgcttcgat
    10981 aatttgttct cttgtggcat ccattttccc gtaggcgata ttatcagcta ccgttccttc
    11041 aaacagccag gtattttgta aaaccatccc aaaagaacga cgtagttctc cacgtgaaag
    11101 cttggtaata tcaagaccgt cgaattcgat ctttccttta ttcagttcat aaaaacgcat
    11161 cagcagattg actaaagtcg tttttcctgc accagttgga ccaacgatcg ctaccgtttg
    11221 ttttggcttt actgaaaaat cgacttgatt catcaatatt ttatctgatg tgtaaccaaa
    11281 ctgtacattt ttgaaagcta tttttccttt cggttgttct aaaagtcttg catctggaag
    11341 gtctggaatt tcatctgttt catctaatat ctcaaatatc ctatcgattg ctgccattgc
    11401 ggattggatc gagttgatca cataagaagc ggtagaaatt ggttcagaaa tctgattgat
    11461 gtactgaaga taagcttgta agaagccgat cgtcacacca cctgatagaa caagcatagc
    11521 accgaatacc gcacttatga tgaaggcgag ttgattaatg aaacgaatgg ccggatagat
    11581 agcacagttc ataaattgag cacgtttaaa agcgttgtat tgctttttat ttacttcgtg
    11641 tatagcagct tctgcatgag cttgctgatt gaatgttttg accactagat taccagctaa
    11701 gatttcttcc attcgattat ttaaaacacc cagttcatac tgattctgtt cagaaatctg
    11761 tttgtttttg ttcgcaatct tagttgtaac aattgaactg ccaacgatca gcaataagac
    11821 gagcaaagta agcttgcttt cgatataaaa cagcatcaga ccagcagcag ctattgttac
    11881 gacagaagta aaaaattgat tgatacctgt caataacact tgagaaagtt gattgagacc
    11941 ggtagttgtc cgactaatga tgtcacctac ttgatgattg tcaaaaaacg acatcggtaa
    12001 tgttttgaat ttttttgtga tttcttttcg caccctcaat gtgatctttt cgcttaacgc
    12061 tgccattgtc cgttcctgaa taaatgaagt gatgctgctt aagactgaac agccgatcag
    12121 caataagaca gggaacaaca atgcttgttt gatatcactg aaagaaagct gtccaatacc
    12181 tgtttttctt atttctgata agagatcatc gatcccgatt cccatgatca agggcatggc
    12241 tacgactaat aggttcccga ataaactgca tagaaacaat ccgtaaaaat atttatgttc
    12301 aggtttgatc attttccaaa aacgtatcaa agcacgcgtg ttcaacgttt ttttcttttc
    12361 catcgtatcc cttctttcta tattccttgt gattttgcaa actcctgata agtttggcaa
    12421 ttagacagta gttcttcatg agtaccttgt ccaacgattt ttccttcatc taaaacaatg
    12481 atgttatctg cttgttggat tgtactgagg cgttgagcaa caatcacgag agttttctcc
    12541 gacatgtgtt tatgaagggc tgctcttaat gctgcatctg ttttatagtc taaagcggag
    12601 aaactatcat cgaatacata gatctctgct ggtttgatca acgctcgagc aatacatatc
    12661 cgctgtttct ggccccctga ataattagaa ccgccttgag caacaaagct gtccaatccg
    12721 tcaggaaggg tgtccactag ttcttctaat tgagcgatct tgatcgcttt agacaactct
    12781 tctgttgagg catattcatt tcccatctgc aagttgctta aaattgtccc gctgaataag
    12841 aaagccttct gagggacata actgatgtgg gagcggatct gttcttgagt catttgagta
    12901 agaggaatac caccaagggt tacttttcct atcgtagggt cactaagtct caagagaagt
    12961 ttcgccaaac tactttttcc agatccggtc ccgccaacga tcgctgttgt ttttccttta
    13021 ggtattgtga aatcaatatc ttctagaact ggatcagaga tttcagtata tttaaatgtg
    13081 acatgttcaa aagcagctgc atttgtctga tcaaaggttg gttcagctac tgttttgatc
    13141 gtctcttcct caatttcgat ctctgcttgc agtatttctt ctatccgtcg taatgaggca
    13201 aacgatttag ggataatgac caataccata gctgcgatca tcaagtaagc aagtgtcagc
    13261 atagagtatt cgactacagc agtcacgaca ccgatttgta atgctccttc tgctacaaga
    13321 tttccgccaa accacaaaat agaagcataa acgattccca tgagcaaaaa agcaattgga
    13381 gtgacccaag caaatattcg gttcactttg atcatttgat tagcatagtc agcaaagctc
    13441 ttattcgttc gcttttcttc atatgattga ttatcaaagg cacggatcat attaatccca
    13501 gtaaagaatt ctctcaatgt gatggtgatc cgatccattt ttggctggat actcaaagat
    13561 aaaggtgccc ctcgtttcat cagtcgataa acaatccata cataaaaaac aacagagatc
    13621 aatgtaaccc atgttagtaa tagagaataa cgaaacatca tgagaatggt gaaaacgcaa
    13681 ataaccggtg ctggtaagat catttggcaa aataaaacaa tcatttgctg gacattatcg
    13741 acatcattcg tcattcttgt caaaagagat ccagaactaa aacgactgat atccttcatt
    13801 gacagctgtt ggaatttacg gaaatatttc tcccgcgttt ggaatccaaa cctagcggaa
    13861 gccaatgctg aaaagtaact agaggcaact gcagcgattg ttcctagaaa cgctacaagc
    13921 agcatttcaa ctccaatttt ttttataact gaggcttcgc cacttgctat acctgtgtcg
    13981 atcagctttg ctactaattt tggtacacct aatgtaccgg cgatttctaa acagatcatc
    14041 acaaaggtaa ggagagcgag tcctttgttt ttctgtaaga atgtttttaa gatagacata
    14101 ttattcctcc ttttttcctg atacttttcg attctatacc ttcaagtaac ttgaaggtca
    14161 atagaaaaaa gaataaactg aaaaagaggt gagaaaaaat gaaaaaaatg tatacgattg
    14221 gccaagtatc ggaactattt gatttgccaa aatcaacgat ccgctattgg gatgaacaag
    14281 gattaatccg ttcaagtaga caagaagaga atgattatcg attgtttgat atcgatgata
    14341 tttttatgct ttatgatatc gttttttata gaaaattaga tataccgatc aaacagatga
    14401 agaatttata tggaaaaaca ttgacggagt tatatgagac acttgatgaa acagaaagaa
    14461 gaatccataa agaactggtg gtgatgaaac aaaaacaaaa agagataagg gagcaaaaaa
    14521 aacagttgaa attgatgatc gatacaaacg aggaagaatt tcctgtagaa gagatccctt
    14581 ttgactgtat gatctcaacg gagtttgaag atattgtgga aatcaaaaaa tttctaccta
    14641 actattcaag ctttgggatg atgagtatgc cagcttccag ttcacagacg atgtatggat
    14701 tttttatcga ccctagtgaa gtacatttat ttactcaaga cgtgatttgg gagaaaaaag
    14761 atacggctgt ttatcgtcga ttcttattga aatccgagat gaaccatgcg gaacgtaata
    14821 atattttaga aatcagagaa agaatgtatg aaaaaggatg gaaaacagga gaagtgatcg
    14881 gccagtatct attgacgaat acggatgaaa acaatatcag aactgaatat tatcatgcat
    14941 ggatagaaat gaaaaaatag gaaatatgtg tttaagataa ctcgaaaatg atggttgttt
    15001 tagttataaa gaaaaatttt ctggttcgat tacgggttta atgtggggga ttattagtcg
    15061 tggatagata gaattttagt tttttagagg aaatatgtct ttaaaaatgg aatggttgca
    15121 attcttagcg atatatacga tgtaattgtc ctcttaaaaa agtatggaaa aataattgta
    15181 ttgggtgtta tgtataattc atggtgaact gagactaatg agaagaaaaa ttcatattgt
    15241 tatgagtgag attgtatcag atgagaatga taaattaaat aggtgcataa aagcattaca
    15301 cttaaaatac attgttgctt acattattac aatatgttaa taaggcaaaa ataaatagat
    15361 ggattgaata aacatatttt ttaatcaaat agtccctact gtgactttcc tcagctatcg
    15421 gtgatactac cgatagcatt tttttgctta taaaataatt ataagtattt agagattttt
    15481 cttctaacat tcttcaaaca agaaaaatca caaaggttat tgttattttt atatattctt
    15541 tttaagaatg attgtttttt tatagaaatt ttaaaaaata aaacacgtta ttgatggata
    15601 gttagtttgt tatttggtaa tattatagaa gttgactggt agtgatttat ttttcgtcgt
    15661 tttataaaaa tgttattttt tggaaaaatt cacaaatatg taacgaatgt ttttctggaa
    15721 tttgctgtgt taaaaagcag tatgactaat ataaatacta ttgtcattta tgcaattttt
    15781 tatggatagt aattttagag gggaatcaat gaaggaagaa tagaagggaa aaatagttgc
    15841 aaatacgcca gttagcaaaa atagcaatac atcttcaagc tttaaaattc gagagaatca
    15901 tcttggtagt ggaatcaact acaacaaaag gattaaacca attaatagat agaattacca
    15961 atggaaaaat agaaaaggta gttattctat acaaaagttg tttaattcgc ttcggttatg
    16021 aacttagtga aaccctttgc aatatatggt acagaatata gaaattattg acattacaga
    16081 aaatgatgaa gatttaatac agattgtcac tatttgtaga taccttttac aaggaaaccg
    16141 agccaataaa gctaagaaga tgattaagga gttgatggaa gacgatacaa gttaagaaag
    16201 tgaaactacg cccaaataaa gagcaaaaag agtaattgga cgtggaaaat gcaagaaatg
    16261 aaccatcgat tcggtggaca gtttattagt aatgacggtt tgagaacatc catgacgaga
    16321 atgaaggaac atcctaaatg cgtttagttg aaccaagtgc caaataatat ggccaaataa
    16381 gcgatcagtt atcgatgaat cccaagtatt ctaaactata tattcatttt gatgctaagc
    16441 attgatatat ttttttggga ttgatgaagg ttaaccaata cagggactca ctgatgaaat
    16501 tctagagtct gaccttggta tcaacgattt agtgattgtt tctaatggaa aagtataaaa
    16561 gtatataagt acattaacaa aataactatt agggttacgc tccagcttgt gcaaggcact
    16621 ggcaggagga atcgtgaaat cataattatg gttaagccac acggacaact aaaagtcata
    16681 caaagctatc gaatcaatca acagaagaca atcggcaatc attagctttg tttacagctt
    16741 acattgcaac gcttgagttg aaccgaaaat acgagggagg taacgcagcc attttgagtt
    16801 ggggaatctt tttagaaaat tatcgggtac cttgttgttt agtcaaaatt ataaggggga
    16861 gtaatagtga ggaacaaatt tcataaactg ttaagtatgt ttctagttat gcttattgtg
    16921 atcaatcaat ttgggaacat aacggttcta gctgagtctt tagcagaaca gccagagcgt
    16981 tcgctgacga tcgaagttga tcaagaggag gctgctttgg gtgagcagtt ccagttgcga
    17041 gtcagaggaa caccagacct gctaaatgca ttggtcattg ataagagtga ggatttgatt
    17101 gaaggggaag tgaagcaact caatgattac gaacgtctga ttacttattc ttcccagcat
    17161 tcaggtaaat acgaattgac cgcaagaagc ggtgatattc aatcaaatac ggtctcaata
    17221 gaaatcagtg taccagaaga aagcacaagt gagtctttta atgtaccaga agaaagcaca
    17281 agtgaatctt ttaatatacc agaagaaagc ttaagtgaat cttttaatga agccagatca
    17341 tctgagccat ctataacgca ggaatctcag attgaaagac aagaggagct cttgaattat
    17401 gacatcggca tctctgctga gcgccccact ttgccgagca ggcatacaca aacgttaaag
    17461 ggatacattc aaggaggcgc tggcgatatt cttgaagaat atggggagat ggtcgtacga
    17521 gttcctagag catcgattgg cttaattgag ttcattagag tggaggtcgc tgatgattca
    17581 cctttaaagc cactggcatt ttaccaagaa ggcacagacg ttgtttttcc atttaccttt
    17641 gattatgaag gattaaatga agccgctcag tcgtatacat tcagtatcac gtttgaagtt
    17701 gctttctttc aatcaggcgg tactgagcca aataatgact ttcaagtgag tcttacttat
    17761 gctgagcgag cagcaaacac ggaattttca attacgccta ttccttcatc aagacccatt
    17821 ttttcgaaat tatactatgg ctctagagaa atcgacagcc aaggaaatct tgggaatctg
    17881 ctgattgacg ggcaagacgt gaccaacagt aataaattta ttttgcaggt aaattatgaa
    17941 ggatcacgaa aagacggtgt agtggttacc gatgtactac cgcaaggaac aactttggca
    18001 ccgaatccga ctacatggag ttccactgga aatagagaac ctatttcagg tggggttcgg
    18061 atcgcagaag taacgaatcc aggtgaagca aacgttagaa ctcattatgt ttccgaggaa
    18121 tttgtggaca aagtatcttt taataaggaa acgaatacac ttgttgtgga ctttggtaat
    18181 ctagcagagg gtcaatcgta ttttattgaa tatgctcttg aagtgaccga tgtcgacttg
    18241 ttcaatgaag gaagacaaga ggatgggttt tctcggaatc gagcgagtat gacctacaat
    18301 aatcaggtaa tgagccgaga ctaccgcttg agaatccctg aaagtaatct tccggcaatc
    18361 tctttaagaa aaagtgtgga caaaaatgtt atcaatctca atgaaaatga actaacgtat
    18421 actctgcatg tctcgatgtt ttctggaaca agaaatacgc ttgttattga agatgttttg
    18481 gaagaaggca tggaatttgt gtcatttcta tcagatattc cctctttcat tgatgccgaa
    18541 gtcaataatg gaatagttcg tttcagtgcg aataatacga ttggtggtcc gacaagtttt
    18601 accctctctt ttaaggtcaa tgtagaggcg tatgcggtcg gcgatcaaat tttaaacttt
    18661 gcaacgcttg tgaatagtga caatcgattg aatacgagta ctgtaagaac aaggaaaatc
    18721 gatgggcgta ttaaagtaat taaaactgat gagaatggcc aaaggctggc aggagcaaaa
    18781 tttgaaattt tatcaagcga ttcacaagtg atacaagaag gtataacggc agaaaacgga
    18841 gaatttttaa gtgaaccgct tcctgtaggt agctatcaag tccgagaaac agaagcaccg
    18901 gaagggtatc ttttagatgc gacggtacat gatgttttta taaatgaata ctccatagaa
    18961 gaagtgacgt taaccattga aaacatcctt gatacgggtg gtgttgaact aattaaacat
    19021 gctgaaggca gtggtgaagt ccttcaagga gctgtttttg agttacagaa ccgagaagga
    19081 gaaacgctac aaaccggt
//
LOCUS       DAIGWC010000057        18822 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.058, whole genome shotgun sequence.
ACCESSION   DAIGWC010000057 DAIGWC010000000
VERSION     DAIGWC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.058"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(99..1229)
                     /locus_tag="NOB74_002015"
     CDS             complement(99..1229)
                     /locus_tag="NOB74_002015"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HCI1221184.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1788..2861)
                     /locus_tag="NOB74_002016"
     CDS             complement(1788..2861)
                     /locus_tag="NOB74_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1221185.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRK"
     gene            complement(2858..3685)
                     /locus_tag="NOB74_002017"
     CDS             complement(2858..3685)
                     /locus_tag="NOB74_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1221186.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(3686..4492)
                     /locus_tag="NOB74_002018"
     CDS             complement(3686..4492)
                     /locus_tag="NOB74_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1221187.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(4504..5589)
                     /locus_tag="NOB74_002019"
     CDS             complement(4504..5589)
                     /locus_tag="NOB74_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221188.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(5606..6148)
                     /locus_tag="NOB74_002020"
     CDS             complement(5606..6148)
                     /locus_tag="NOB74_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1221189.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            6406..7395
                     /locus_tag="NOB74_002021"
     CDS             6406..7395
                     /locus_tag="NOB74_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCI1221190.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            7392..8129
                     /locus_tag="NOB74_002022"
     CDS             7392..8129
                     /locus_tag="NOB74_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HCI1221191.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            8126..8677
                     /gene="coaC"
                     /locus_tag="NOB74_002023"
     CDS             8126..8677
                     /gene="coaC"
                     /locus_tag="NOB74_002023"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HCI1221192.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            8693..9325
                     /locus_tag="NOB74_002024"
     CDS             8693..9325
                     /locus_tag="NOB74_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI1221193.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            9410..10057
                     /locus_tag="NOB74_002025"
     CDS             9410..10057
                     /locus_tag="NOB74_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1221194.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            10062..11045
                     /locus_tag="NOB74_002026"
     CDS             10062..11045
                     /locus_tag="NOB74_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HCI1221195.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(11448..12962)
                     /locus_tag="NOB74_002027"
     CDS             complement(11448..12962)
                     /locus_tag="NOB74_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HCI1221196.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYSVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            13100..13906
                     /locus_tag="NOB74_002028"
     CDS             13100..13906
                     /locus_tag="NOB74_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221197.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(14081..14650)
                     /locus_tag="NOB74_002029"
     CDS             complement(14081..14650)
                     /locus_tag="NOB74_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1221198.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(14733..16793)
                     /locus_tag="NOB74_002030"
     CDS             complement(14733..16793)
                     /locus_tag="NOB74_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HCI1221199.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(17070..18548)
                     /locus_tag="NOB74_002031"
     CDS             complement(17070..18548)
                     /locus_tag="NOB74_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1221200.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT         5585 a         3768 c         3272 g         6197 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaatt ctaagaatag gtcattatag atgcctaggt atttcgatcc tagatctttg
     1861 tagacttcaa gatgggagat cgtgtcatca gatggataga attgttcgtc cgacgaaatg
     1921 tcttttggca ataacgcttt tgcttcttca tttggtgtag aataaccaat atactctgca
     1981 ttttgtgccg cattttccgg ttctagcata aagttgatga aatcataggc accttcttta
     2041 tttttcacgg tttttggcat aacgatatta tcaaaccaaa gattggatcc ttctggtggg
     2101 atcacataat gtaaatgttc attttcccac atcatatcgg cagcttcgcc agaaaatgtc
     2161 actgccacgg aggcttcttc attgatcata tacattttga tctcatctgc cacgattgct
     2221 ttgacatttg gtgttaaatg attcaattta tttgctgctt ctgtcagctg tgccatattc
     2281 ttactattca aagaatagcc taaactattc aaagaaagcc ccataacttc tcgtgcaccg
     2341 tcaatcagca tcaaactgtc ttttaattcc ggcttccaca aatcatccca atgcttaatt
     2401 tgatttgcat caaagaattt atcgttatat acgatcccta aagttcccca aaaatatgga
     2461 atcgaatact gattatctgg atcaaaatcc aagtctaaaa atcgtggatc aatattattt
     2521 aatcctttga tcttcgaatg atctaatgga agtactagtt tttctttgat cattttttgg
     2581 atcatatatt cacttggtat agcgatgtcg tagtttgtcc caccttgctg gatttttgtg
     2641 aacatcgctt cattagaatc aaatgtttca taattcactt tgtatccata ttctttttca
     2701 aatttcgtga tcaaactagg atcgatataa tctccccagt tatagatggt aagtaccttt
     2761 gctccactca tgccacttgt tttttcaagt tgacgaacac caagcagcag caccgcaata
     2821 atgatgagaa tacctaaaaa cagagattgt aattttttca tcgcagccgt gccaccccct
     2881 cgcgtactct tctgtttttc ttcagccgtt ttggacggtt ttctttacta ataaagtagt
     2941 atccaatgac caatatcatg gagaacaaga aaactaacgc acttagcgca ttgatttcta
     3001 aactgattcc ttgtcttgca cgagaataga tctctactga gagcgtcgta aagccatttc
     3061 ctgtgacgaa aaatgtaacc gcaaaatcat caagagaata ggtaaatgcc ataaaatatc
     3121 cagctatgat tcctggagaa agataaggca aaatgatatt tttgactact tggaaattat
     3181 tagcaccaag gtctctagcc gcatcgacca ttgaatcgtt catttcctgc aattttggca
     3241 agaccatcaa gacgacgatt ggaatgctga aagcaatatg ggaaagcaat acactctgaa
     3301 aacctaatcc gaatcctagt agtgtaaaga aaatcaagaa actagcaccg ataataacat
     3361 caggagagac taataagatg ttattcatgc tcaacaacgc tgtccgtgca cgtcgttttt
     3421 tcgtgtaata gattcccata gccccaaatg tcccgatgat cgtggcgatc aatgcagata
     3481 agaaagccag catgaacgta ttcaatacga taatgatcaa acgtgtatct tcaaaaacag
     3541 cttcataatt ttcccaagta aatcctgtaa agctgttcat cgttcctcct tcattgaagg
     3601 aataaaaaat cagatagaag atcggtgcat ataagaataa aaagacgatc cctaaataaa
     3661 gatacgacca tttaaatttt ttcatttatg agcgacctcc ttttttcttc tcgcctgtca
     3721 ggagcatcac gatgaacata gcaatgatta aaatcacacc gattgtagaa cccatccccc
     3781 agttttgtgt aaccaagaaa tgctgttcga tagccgttcc taaagtgatc acccgatttc
     3841 cgccaatcag acgagtcagc atgaataaag aaagagaagg aataaatact gcttggacac
     3901 cacttttcac accatttaat gataacggaa aaatcactcg tcggaaggtc tcaaagctat
     3961 tcgcgcctaa atctctacta gcactgatca aagaaggatt catctcttcc aatgcattga
     4021 aaattggcat aatcataaat ggaatctcga tatacgttgc cacgaacaga aaactgaagt
     4081 ctgtgaataa tatctgtttc ggcccgatcc cgataaaatc aaagaaatga ttcacgctgc
     4141 cgtgcacact gaaaatccca ataaatgcgt aagctttaag cagcagattc acccatgtag
     4201 gcaaaataat cagcatcagc cataattgct tgtgcttcag ttttgttaaa aaataagcag
     4261 tcgggtaact gatgatcagc gtgaaaaacg tgatcaaaaa tgcataccat acagaattga
     4321 tcgtcataga aagcgatgtc cccgacgtaa aataagatag ataattattc agcgtgaatt
     4381 gcccattcat atcaaaaaaa gattgataaa tgatcattaa tacaggcgcg atcacgaata
     4441 aaccgagcca caaaatataa gggacggaat agatcctgcg cattgttttc attcttgtcc
     4501 cccctattct tcgtagctgt caagacgtgc atcgaattct tcttcagact cgttgaaacg
     4561 catgacatgg atatcttctg gctcaaaggc caatcctact ttgcttcctt ctttagcttt
     4621 tttcgttgaa tggaccatcc attcattttg ctgttcatca taacagatga tttcataatg
     4681 gacaccacga aacagctgag tatcgaccgt tacgactagt tttcctttat ctggtgtcgt
     4741 gatcgtcaaa tcctctgggc gtaaaacaac ttcaactggt tcatttagac gcatcccgcc
     4801 atcgacacat tcaaattgct taccaacaaa ctcaactaga ttatcttcga tcattacacc
     4861 gtccacgata ttgctctccc caacaaaatc agcaacgaaa tgattgattg gctcatcata
     4921 aatatctacg ggtgtaccac tttggacgat tttcccttta ttcatgacaa aaatctcatc
     4981 actcattgcc aacgcttctt cttggtcatg agtaacaaaa ataaacgtga ttcctaatcg
     5041 ttgttgcaga tcccgcagtt catactgcat atctgtacgt agtttcaaat caagcgccga
     5101 taacggttca tctaatagca atactttcgg ttcatttaca attgctcgtg caatcgctac
     5161 acgctgtctt tgaccaccag acatttcact aatctcccgt ttttcgtatc caggaagctg
     5221 gaccatacgc aaagcatctt ttaccttctt ttcgatatct gatttggaca ttttcttgat
     5281 cttcaatcca aaagcaacgt tatcaaaaac attcatatga ggaaaaagtg cataatcttg
     5341 gaagactgta tttacttgtc gcttattagc tggcaaatca ttcaaccgtt tcccttcaaa
     5401 atagatgtcc ccttctgtag cttcggtgaa tccagctata atacgtagga tcgttgtttt
     5461 accacagccg gaaggaccaa gcagtgtata aaattttcct tgttcgatct caaaacttac
     5521 tttttttaat actgtttcat catcatagcg tttcactact tgatcaaatg aaatgattgg
     5581 tttccccacg tttttacccc ctatattaca aatatgattg cgttgcaaca atcaatactt
     5641 ttgttcgttt tttgagatga ttccttaatt gatgttgttt tgtcgcttga taatagatcg
     5701 actgtcctgc ttttgccaca tagaccgtct ctcctaagct taactctaat tccccttcta
     5761 atacaaaaat aaacgtttca gataatgaag gttcaaacgt cttatattct cctgcacctt
     5821 caaaagtcag caagacaggc tccatttctt tttcattcga atcagccacg agccattcca
     5881 attcataccc gttttcttca tcgaaataaa ccgtatgatc ttcttttgaa taaaccactt
     5941 gcagattcgc tgcttcttga tgaaaaaatt cttctggagt cacacctaag acttcaagaa
     6001 tagaaaagaa tgtttccatt gatggtgaac ttaaatctcg ttccaactgg gaaatatacc
     6061 cttttgacaa atctgtgcgt tcgcctagtt cttcttgtgt caaattcttt tggatgcgca
     6121 aatttcttaa cttctcacca atttccataa tttcctccga atcgaagttt tctaatagta
     6181 aacttcctgt ttactaccac tcgtattagt atacgaaatt tattgaaaaa ggcaaccctt
     6241 tgtaaaattt tttttgctga atatttcttt atcttttgga ataaattcta gttgtttgat
     6301 tctttatttt tcacctaatt tttgtctaaa tttacggaag aacaagaata aaagagtagg
     6361 ctttatggta tgataaaaga aaattttaaa aggagtgtct cacgaatgaa cgcttttcga
     6421 tcttttcagg taataaagga acctgttttc catacagcaa tcagtgatct gccatttact
     6481 gagttggctg aaaatgaagt cttggtaaaa attgcctatt ctgatgtcaa ttataaagat
     6541 gcattggcaa tgagcgagtc tggtcaggtg atacgaacat atccgatgac tccagggatt
     6601 gatttatccg gaactgtcgt ccaaagtaac aatccacgtt tttcaaaaga agatcttgta
     6661 cttgctactg gttttgggct tggcgtcacc catccaggcg gttatagcca atatcaaaaa
     6721 gtaccaggag actggttagt tcctctacca aaaaatatga cgctgcgtca agcgatgatc
     6781 cttggtacag cagggtttac tgctatgttg tgtgtgaacg ctttaatccg tcaaggtatg
     6841 acctccgata aaaaagttgt cgttactggt gcttctggcg gtgtaggcag tacagcgata
     6901 gccctgttac ataaactagg attccagtca atcattacct tttccagaaa agaagagtct
     6961 gtcacatggc taaaaagtct aggtgctttg caagtcgtac gacctgatga atttctgcca
     7021 gagacaacaa aagctttagg aaaacagcaa atcgactatg tcatcgacac agtaggtggc
     7081 gagcagctaa gcagtcttct tccattgatc tcttataacg gtgcagtagc tttatgtggc
     7141 aatgctgggg gaatcaaact aaacgcgact gtcttgcctt ttattctgcg aaacatccag
     7201 ttgattggaa ttgattctgt caatgtacca atagatcaac gtctttcttt atggcaacag
     7261 atggcggatt tgcagattgc agatgaactg gtcgtccaag agattactct ggatcaattg
     7321 cctgaaacag catctaaact acttgctgga acacaccaag gaagaacact agtaaatgta
     7381 ggtgaccata aatgaagatt ctaatcacag ctggaggaac gactgaaaaa atcgatcaag
     7441 tacgtgctat tacaaatcat tcgacaggac gattagggca agcattagct gattatttag
     7501 ctgccaatcc ggataccaca atcgattacg tgactacgaa acaagcactg aaaccgaaaa
     7561 gacactccaa tataacgatt tatacgatcg aatctgcact ggacttattt ttacaattag
     7621 aagaactaac gaaaaaagaa cactacgatg cgattatcca cagtatggca gtcagtgatt
     7681 ttactcctgc ttttagtttt tcagaagaac agctggcaaa aaacctaccc acttcttcaa
     7741 cgcaagaaga actggacaat tggtttgcgg aaaatgaaca gacagatacc actgtttcaa
     7801 agatctcttc taacaccgag catcttgtgc tcgttttgaa gaaaacacca aaaatcattt
     7861 cttatctacg tgaatggcag ccaaaagcaa aaatcattgg tttcaaacta ttagtagatg
     7921 taccaaagga atctcttctg gcagtcgcaa aaaatagtct gataaataac aaaactgatt
     7981 ttattttcgc aaatgatttg acggaaatcc atggcgagac acaccacggc tatctcttat
     8041 ctaaagatgg aacagtggaa gaagctcaaa gtaaatctga gattgctgca ttgattactg
     8101 agaaaattag actggaggaa tcaaaatgaa aaagatctta ctaggcgtta ctggaagtat
     8161 ttctgcttac aaaagcgctg atcttacaag tcaattcgtc aaattaggtg cccaggtaga
     8221 tgtgattatg tctaaaagca gcacacattt tatcacgcca ttaaccttgc aatctctgtc
     8281 gaagcgcgca gtccatacag acgtcatgca agaatcaaat ccgcaggtaa tcaatcatat
     8341 cgaactagca aaacaagctg acttgtttct catcgcgcct gctacagcaa acattatcgg
     8401 caagctagca aacggcattg cagacgatct tctttcaaca gtcgcaatgg cgcttccagt
     8461 gggaacacca aaattgattg cccctgccat gaacacgaat atgtatcaaa acccgatcac
     8521 tcagcgtaat ctggaaacat tgagatctgt cggctatcag gaaattgaac caagagaatc
     8581 tcttttagct tgtggagatt ttggaaaagg tgccttagct gatattcaga cgatcatcga
     8641 acaggtcatg ctgactctta atgaaagaaa tgcttagaaa aaaggagtac ttatgaaaaa
     8701 tacaaaaaac tttacattaa ctgcgatgtt tttagctatt ttgattttat tagctgttac
     8761 gcctttaggt tttatcccta tcggtccaat caatgcaaca accatgcata ttcctgtaat
     8821 cattgcttcg atcgttttag gaccaagact aggtgctttt cttggcggta catttggact
     8881 gatcagcatg atccgtagca cagttatcca aacacctttg tcttttgtct tttctccgtt
     8941 tatcccagtc atcggaacag aacatggaag ctggaaagcc ttgctgatcg cgtttattcc
     9001 tcgcatcttg attggggtgg ttccttattt cgtttataaa ggtctgcgca aactaatgaa
     9061 acaaaaagca gattccgttt ctttattctt agctggactt tccggttcat tgaccaatac
     9121 gattttagtg atgaatatga tctacttttt attccagcaa gattatgcca aagtcatcgg
     9181 aacaaattta aatgctgttt attcagctat tctagcggtt atttttacaa gtggtatacc
     9241 tgaaggaatc gtcgcaggtc ttgcgactgc agcagtatgc aatgtcttgt taagatactt
     9301 caagcaccct tctcttacta actgatagtc atcgtagccg atctctgatt tttttctctt
     9361 ttggtgttac tattgaatgg aaagatttga cgtcgaaagg atgatccaaa tgaaaatttt
     9421 tgttgtaggt gcaaacggac aaattggccg acacctgata aaagatttag ctccaagttc
     9481 ccatgaaatt tttgcagggg tgagagatgt tgcttcccaa acattagtaa aaaaagagaa
     9541 tgtttcgtat gtctcttttg atttaacttg gtccgtggaa aaaatgaccg aagcattcaa
     9601 aggcatcgat gtattgattt ttgctgccgg ctctcaagga aagaatcttc tgcaagtaga
     9661 cttggatggc gcaatcaaaa cagtgatcgc agctgaaaat gcgcatgtct ctcgctatct
     9721 gatggtcagt gctgtttatg cagatgaacc agcaaaatgg cctgagtcca tgacagatta
     9781 ttatattact aaacattatg cagatgaatg gctgaaacga actaacttag attttgtcat
     9841 tcttcaacca gtcacattga ctaacgatga agaagttact tccattcaat taactaagcc
     9901 taatgagaag gcatcaaaaa cgatcactcg ctctacagtt gctgctgtac ttgccgctct
     9961 agtggaagaa acggatattt ctcgtacgac tctagtactt tctgaaggta gcaaagagtt
    10021 gaatacagca ttccaagaat gggcaaagga ggaatagatc catgcgtgcc atttcaatca
    10081 agcatcctgg ttctgtagat gtattagaac aaattgaagt gcctgttcct aaaccaaaac
    10141 aaggcgaatt actgatcaaa gtccatacag cagctgtcaa tcgaacagat attatgaaaa
    10201 gagaatcagt ctctttgaaa cctccctacc ctattttggg agtcgaagta gctggagagg
    10261 tagttgagaa taaaagtgat atctccactt ttactcctgg gacaaaagta tacggattag
    10321 tcaatctagg tggttatgcc gaatatgctg tgatgcctgc cgatcgtgca atccttctcc
    10381 ctgatacgct agactatgtt tctgctgctg gaatctcaga agtttttttg actgcttatc
    10441 aaacacttta ctggcttgga aaattacaag aaggcgaaac tgtcttgatc catgcaggag
    10501 caagtggtgt gggaacagca gcgatccaat tagctagaca gctttctcac gcgaaaatca
    10561 tcgttactgc aggatcagaa gaaaaactcg ccttttgtaa agaacttggt gcagatgaat
    10621 tgatcaacta taaaaaacaa gactttcaag aagaggtacg aaaaatcact gaaggtcggg
    10681 gagtcgatgt tattttggat ttcatcggcg cttcttactg ggaaaagaat ttagcttcta
    10741 tagccgttga tggacgttgg gtcttgattg gtatgctagg tgggaccatc gtgcctgaga
    10801 tagaccttgg tgtattgatt gggaaacgtg tccaactgct tggtacatta ttgacaccta
    10861 gaagtgatca gtataaagca gagctcgcac aaacttttat gcaaaaagct gggccttttc
    10921 tagaaaatgg caagattcgg ccaatcattg accgtacatt ccaattcagc gcagtcaaac
    10981 aagcgcatga atatatggaa gcaaacaaaa acatcggaaa aatcattttg aagataactg
    11041 aataaaatca tgctgatcaa aaaagaggct gggacagaag cgtttaactc caagaaataa
    11101 gaagaaattc acgaaaattg cttttcaaat ttttgtgaat ttcagcttat ttccgaagga
    11161 atttcttctg cttccgccgt ttatacgtgt ttagagcgtg agacaaaagt gttctttact
    11221 tttgtcccac gctctttttc cgaataaacg gtgttcaaaa gcttgcatct gcggtaataa
    11281 gtccaaccaa gttaaaaaca taagaagctg tttttacttg gctgttctta ttacttgatg
    11341 cagggcagct ttttcacaac ctcttcacta aacagtgttc aatcagctga ccctcggtat
    11401 tagctcaaaa cgctgatttc acaacctctt tttatttacg ttctatttca ttcattttcc
    11461 gaagcaaatc gagctgcttg tatgcccgct tgtcgcccaa aaataatgat ctccgcaact
    11521 gaatttccac cgatccggtt gtttccatgt aagccacctg tgacttcacc agcagcatat
    11581 aaccccctaa ttggctggtt ttctttatct aatacttcag tgttcgtatt gattttcaca
    11641 ccgcccatcg tgtaatggat tcctggtgcg attttgatcg cataataatt cggagacgat
    11701 aagtcatgtt ccatggctgt ggcacggttg aattgagcat cttttttctc cgcaacatcc
    11761 gtattccatc catcaactgt ttttgctagt gtttcttttg gtaaatcgat tttttctgct
    11821 aattcttcca ttgtctttcc agttgtgaca tatccttttt ggtcataaaa ttcaatagct
    11881 gtggcacgat cacgcacgcc ttggtcaaaa atcaaataag ctgatttttc aggcaatgct
    11941 gtaattgctg cagatacttt atcccttgta tccatttcat tgacaaatct tttcccctct
    12001 tgatcgacca agattgctcc ttctccgcga acaacctcac caatcaagac cccctcatcc
    12061 tgctgcacag ttggatgaat ttgtatttta tccatatcaa cggtttgtcc acctaatttt
    12121 tcaatcatgg tgataccatc tccagttgat ccttcttgat ttgtcgtaat ataatcagct
    12181 aaatcgggac gatatttttc aataaattct ttgctggcac caaaaccgcc tgtggtaact
    12241 acgattgctt ttccggtgac ctcttttggt tcttctcctt gaacatgtac agtcacttca
    12301 ttgaccgttt ccccattttt cttaatgtct gtcacatctg cgttgacaaa aatagggatt
    12361 tcccgctcat ggacgttatt caataacccc tccactaagt atccaccaat agccgagcca
    12421 tcagacggac gatgtgtcct cttttcactc atccctccag tgatcgttaa gttgtccagt
    12481 ttgataccgt tttgatctag ccaatcgacc gcatcagcag agtgatcgac agagtatcga
    12541 agcatttctt tatcattcgt tcctccacca ccttttagcg tttcttcata gaaggcatca
    12601 ttcgagtctt tgattccttc ttctttttga aattttgttt ctgaagcatt cataccgctt
    12661 gatgatttag atgtgtttcc tccggcaaca ggcatctttt ccaaaattac tggattcaac
    12721 ccagcatctt ttgcttcgat agctgctgcc atccctgcac caccagctcc aataatcacg
    12781 acatcataag attctttcat ttcttttgga tctgtatata cttgttcaga agcgcctgat
    12841 gatacttcgg cagattcctt cgtactagaa cttgtctgcg ctgtattttt ctgatctgcg
    12901 ccgcatgcgc tcatagcaag aagtgcaacg gctgttaata aaccagcaac taattttttc
    12961 atttgtatcc cccttttctc cttatactat attaagtgat ttttttcaca atatcaactc
    13021 tgtttttctt taagtcatat agctttggta aacacacgct tcttagtata attaaggata
    13081 tacatgaagg agttatttta tgaatcattt gaaaaccttt tttacgaaca gtacaaaaac
    13141 tgcaggtaga atcacaaacg gaatctatat tttattacgt atcatcgtcg ttattatgct
    13201 agtggatcag gtctggaacc aacactgggg aaatacaatg cttttattac tgacattaat
    13261 tttatttgaa atcccttatt ttctggaaaa gatattaaag atacagattc caaatatgct
    13321 agaaatcatt ttgttatctt ttatttttag ttcaacagtt ttaggagagt taagtgattt
    13381 ttatggctat ttttcaatgt gggatacttt tctacatgca ttcagcggat ttttagctgg
    13441 gggtgtcggc ttttcccttg tttatttgct caataaaaat acaaaaacca tgaacttgac
    13501 tcctttatta ctagcagttg tttccttctg tttttcgatg acagttggtg ttatgtggga
    13561 gtttgtggaa ttttcagcag ataaattact gcaattcgat atgcaaaaag atacgatcat
    13621 ccagcaaatc aatagtgtgg agttaagtaa agacggaaac actgtctatc atgttccaga
    13681 tatcactcgg acaatcattg aaagtcaaaa tgcagatggt aaaacagata aaacaatcat
    13741 ccaaaatggt tacttagacg tgggaatcat ggatactatg aaggatttat ttgttaattt
    13801 tattggagca gttgttttca gtgtatttgg ttacctctat agtcgaaacg attaccaaaa
    13861 atttacgttc atcaagaatt ttattcctaa aaaaatcaaa cgataaaaca tgctaaaaaa
    13921 caagagaagg ggcagtgaca atacttttgt cactgcccct tcttttttga atgtatggca
    13981 tgccattagt tatccgatag tattaactca aaaaagtaag atatgaggaa tgactatttc
    14041 gttttttatc ccaatactga ggacttattt caccatttcg ttatttatct aatttactta
    14101 aaacctgcat aactttttca taatctggat taggtgtgcc gtctagattt tcagcaataa
    14161 aagtaaaacc cattttttta taaagagcaa tcgcctgatg gctccatgtc tgtgtgtgaa
    14221 gatagattgg tccgtccgta tggagggtag gaaattcttg caagactctg gcagtcaatg
    14281 cttttgcgag cccttttcct tggtaatctg gtttcactgc taaccaatga aaaaccggat
    14341 acacttgctc tcttgatttt tttcgccaag cggtacaggt tgctactttt tctccttttt
    14401 ttgtctctac aaaaaacatc cttctttcaa gttcttcagg ataaggagca aagttttgtt
    14461 gaaaatactc aagtgcttca tctgtcgttt gaaattcccc aacggaagtc tcaatctccg
    14521 cccaagcaga ttcatcttct ttttgataaa atcgaaattc aaaaccttcc gctaaaggcg
    14581 tgattggaac attttgttga agtggtcttg tcatccagat ttctgcgtaa ggtaacgttt
    14641 tatctaacat ttttctatcc ctcctcgtct ccattatgcc aaataacata tgactcagct
    14701 acttatttga ctataacaga tagagatata aatcagaacc agtcatctgc gtcaaattca
    14761 tttcgattag cgtataccca tgttcctgcc atacctcgca tgaaatctcc taaagcagaa
    14821 gaaggaatac ctccaccagg tgcgggtgtt cccggactag gaagtggtac ttgcggctgc
    14881 agatgctcat cggtggaatc aatagttgac aagcgttttt tcttcgtttc cttctggtca
    14941 tctgattcct tctgatcttc cgactgttta gcaacaaatt ctttttctga ttgttgtttt
    15001 attttaggct ctaaaatttc attttccaat ccagaaactt gtggggccaa atgagcttct
    15061 tgccttatcg ttttattaga ttctgagatt tttctagata ttcttgctaa ctctaggctt
    15121 cttgtttgtt ttactttccc tgttggagaa actgcatgag ccatttgttg ttttttttct
    15181 gacaagcttt cttcttgtct tttttgttct ttttgatcta tctgtttgtt taatggtaaa
    15241 acatgtaata gtgactgagc atggagttct tggagtgaat acgggtcatg ataactatac
    15301 ataatcgtaa aatcacctgt ttgtttggtc aaataaccat cctccaatgg tacttcattg
    15361 attgtaaccg atacatcctt taacggtacg ggtttaccta aggaatttgt tgctgattgg
    15421 atcaactctt ctttgtttat tttttcgttt ggatgaacaa taagatcatg accttctaat
    15481 gaacgattgt ctggtatata aacataagta aaggtaattt cccctcctga ttgcttccta
    15541 ttattcatca gttctgagtg aagtacttca aggatctccg accagtgact ttttctgtct
    15601 aatccgtttg cttgcatcca atcagaaata gaagtgactt tcccattttg ttcataagtc
    15661 gataaatcta tatttggcac tcgatcagaa aattcagcag gtaggcgcaa atcaggaata
    15721 cgatttacac tactcatatg tgtttctgct tgaagttctt tatttgtttg actatctata
    15781 aaatgagtga tgacagtcga tgaagcagca gatgcttcta cataaactac agctgttgtt
    15841 tctgccacat ttgatgtttt cgagtctata taagttaata caacgggata ttctcccgga
    15901 gttgtagtat ctactgtccc gttcattttg atttcttctt tatttcctga agttccatcg
    15961 ctttttgtta catattcaac aagatcttta ggggcgtaac tctctcctgt tcttaagtga
    16021 agatcttttc ctttgatagc tgtttgatca gcacgaacat ggatcacagc agatgcagtc
    16081 attgttttta aagcaattgg atcaaaatag gacaaggaaa tagtagatgt tcctgtatta
    16141 gtcgtatcca cgatattccc attgtttgaa attactttgg acatatctcc ttgtgttcca
    16201 tctgcgttct tcagcctttc taccagatca gatatcgaaa cttttgtccc tgccagaaca
    16261 tcgattttct ttctttcaaa ctgtgaataa tctttttcat atacataaga aacttgtgcg
    16321 cttccaccgt cctttatatc tgtcaaagca tgattcaaaa tatcagtgat ctgttttaac
    16381 tgatcacctt ttgtaggatc agtcatatcg gaaaagatag aaagcggcac actgcttccg
    16441 gtttccgatg tccataatgt tttgttagga attaaccagt agtggtttat cgttggagga
    16501 taactgactt tattatagga agtcaatgca ggaagtagct gttttccatt tgcatcagtg
    16561 aaagtatgag taatagtgat aggggaatca gtggtctcag aaacagaggt acgtacgacc
    16621 ttgatggttt gtgtcgttgc ctgaacgggt acatgcatat agacacctac agataaactg
    16681 atcagcatcg tgcgcatcat aaacttaacg tagtgttttt cagaacacga ccgttcctta
    16741 tctaaacgac aagcgtgttt atttagttgt tttgaacgtc tttttgaaca catttattct
    16801 tagtcctccc tactcttgtc taaacatgaa gtagtaattt tcataagatg atttcattat
    16861 ataaataaaa tcaaaagaag atggactatt aggagagtat tttttttgat tttttattgt
    16921 ttcaagaaaa tcggaataat aacttatgta ctttttaatt ttgttaagta atatatctag
    16981 ttatatctag ttatatctag ttaccttttc tttgaaaaaa acataaatca gctaataaat
    17041 atgtgagaca aagctgccat ccataaatac tagctgattt tttcagttaa atgtctattt
    17101 ttttctctga tgatggtatt tccaaaatat tcccagtcat ctggagtcgg tggatttttc
    17161 caaattatct gttctttatt aaatttttca agtaaacaat cagataaata aatattcgta
    17221 cgagaagtga ttcgactctc aatcacaata ttgtaatttt taaatccttt cacttgagaa
    17281 ataatgtaat cggtataagc agatccttgc gaaaaatcaa tacagacatg aatcggtgct
    17341 tcaaaatatg ataccggaca aataccgacc aataaaaaga gataatcata aaataagcga
    17401 atcatgaaac gttcatcttt tcccaagaaa tagcgtttat tctcttgtat gaccttttgg
    17461 attgctgtac tgaatattgg atacgtctcg aagaaaaact gtagctgctt tttagacgta
    17521 aagctagtca tctcaaagtc gaatatccaa ttttttcgat tgacatgcat catacccata
    17581 cgaagttctt ttcgtatata tagtctttct tcttcagaga tttcaatcga aaatggtaat
    17641 tgatcaatca attccactga cattttttga ctaatcatgt ggatatcatg aaaatgagct
    17701 tccgcaagtc caaatgcgcc atctaattca aattcttctt ccgtgatcaa aaacaacatg
    17761 atataagaaa tctcatcaat gatctgctct ttagggatat gaagaaaaga aatatgtgat
    17821 aaatccttga tgatcttcat tccttctgag ctcttaaagt attcatctga aaagaaacgt
    17881 tttccgattg gttgattccc ataggccctc aacaaactaa tagtggttag caaattgaat
    17941 ttgattcgtt ttgttgcaga cagttttaaa ttgaacagat attcaaaata ttgcacgata
    18001 ctctttgctt cattcatgac gctttctcta aatggcatag aaaaaccatt aaagaccccg
    18061 aaatataccc caaataatac gttccgtatg tttatttctt ccccaactaa tatgtttttc
    18121 tttaacttta tttgatgctg ttcaagaaaa gagactaatt ctcttctttt tacataggct
    18181 cttgatatgc ttaaaaaatg attctctgca aatttttcga tcgttacttt tgaatccacg
    18241 atctccgtta acagtcgagc aatttttgat cgttgaaagt agattcttct taaatttttg
    18301 atatccgtca aattcagacg ttcgacatgg atctctgctt cttctgaaat ttggatctct
    18361 ggctttgttt tgaattcagt aaattcttta tttaattcta tgatataatt tcttgtttta
    18421 aatttagaca aacctaatgt ttcatataac ttaggcagca ctacataatt ctttttctca
    18481 aattctaaat atctagctag cagcagtttt tctctatctt cctcttctat aaggtaatcc
    18541 aacttcatat cctacacctc aaaaaatgcc tcataccaat tacttgatat gcagatgaaa
    18601 gttcatcttt tcacctatac tgattttatg atggattatg cttgtttttt catcagttat
    18661 tctcattttt tatctttttt ttgagaatat tgcaaaaaat ggaaaaattt atgaggaaat
    18721 attctatatt ttttgtttta ttgtgttaaa atgtacaaga tttgcgccat ttgcgtaaac
    18781 aaccacaaaa aagagcagga cggccaccgt cctgctcttt ta
//
LOCUS       DAIGWC010000058        18539 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.059, whole genome shotgun sequence.
ACCESSION   DAIGWC010000058 DAIGWC010000000
VERSION     DAIGWC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.059"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(543..1157)
                     /locus_tag="NOB74_002032"
     CDS             complement(543..1157)
                     /locus_tag="NOB74_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1221201.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1763..2140)
                     /locus_tag="NOB74_002033"
     CDS             complement(1763..2140)
                     /locus_tag="NOB74_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221202.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2440..3321)
                     /gene="galU"
                     /locus_tag="NOB74_002034"
     CDS             complement(2440..3321)
                     /gene="galU"
                     /locus_tag="NOB74_002034"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCI1221203.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(3364..4383)
                     /locus_tag="NOB74_002035"
     CDS             complement(3364..4383)
                     /locus_tag="NOB74_002035"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCI1221204.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(5016..6020)
                     /locus_tag="NOB74_002036"
     CDS             complement(5016..6020)
                     /locus_tag="NOB74_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1221205.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(6033..7082)
                     /locus_tag="NOB74_002037"
     CDS             complement(6033..7082)
                     /locus_tag="NOB74_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1221206.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(7099..7920)
                     /locus_tag="NOB74_002038"
     CDS             complement(7099..7920)
                     /locus_tag="NOB74_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI1221207.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(7907..8686)
                     /locus_tag="NOB74_002039"
     CDS             complement(7907..8686)
                     /locus_tag="NOB74_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1221208.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(8703..9173)
                     /locus_tag="NOB74_002040"
     CDS             complement(8703..9173)
                     /locus_tag="NOB74_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1221209.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(9185..9604)
                     /locus_tag="NOB74_002041"
     CDS             complement(9185..9604)
                     /locus_tag="NOB74_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HCI1221210.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(9685..12462)
                     /locus_tag="NOB74_002042"
     CDS             complement(9685..12462)
                     /locus_tag="NOB74_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI1221211.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            12653..12877
                     /locus_tag="NOB74_002043"
     CDS             12653..12877
                     /locus_tag="NOB74_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221212.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            13656..15371
                     /locus_tag="NOB74_002044"
     CDS             13656..15371
                     /locus_tag="NOB74_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221213.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            15374..17137
                     /locus_tag="NOB74_002045"
     CDS             15374..17137
                     /locus_tag="NOB74_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221214.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(17177..17713)
                     /locus_tag="NOB74_002046"
     CDS             complement(17177..17713)
                     /locus_tag="NOB74_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCI1221215.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(18036..18458)
                     /gene="mgsA"
                     /locus_tag="NOB74_002047"
     CDS             complement(18036..18458)
                     /gene="mgsA"
                     /locus_tag="NOB74_002047"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HCI1221216.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
BASE COUNT         5495 a         3804 c         3150 g         6090 t
ORIGIN      
        1 aaaatctcgt cctgtttttt tcattttaca atcattgaaa aattgaattt cattgcaaaa
       61 aaaataataa acacttataa atatccatta tctatccttc aatttttgtg tattttattt
      121 ctattagaaa aaggtatcct gttggacaat tttgttatat caggtaaact tcattgcaat
      181 aatgataaca aatgtactat aattactttg taaagagttt tggggaagac tctttcatca
      241 acgtgtatta agagacaaga aagaatccat atggattctt tcttgtctct ttttccacta
      301 ctttttattt ttctgacact acatattctt ataactcatt tctcataact gtgaaacaac
      361 ttataaaaat aacaaacttt aaacaaaaca agcttaaaat caaagatgat ccatcttaaa
      421 ataactaaaa caaaaaaagt agtcgttgtt aatcctcatt aataatcgtt ttcttttttt
      481 caaacgctcc atttttatgt ggaacattat ttttttaagg aactttgtca acatgtggat
      541 aactattttc cacttgtgtc ctggactagc tgttttgctg taaaatacaa aacttgctgc
      601 agcaaaaaga tcgttgcaag agaggctgtt ccgcagatcg ctggatctag atttggcaaa
      661 gtcaagactg catcatgtaa attggcgtgg ttgtccaaaa ccaaatcagc aaattcaaat
      721 aatcgcaaac cactgctatg ttgcgatttg atacttcgtg acaaatcaaa tccagtaaca
      781 atgattaatg gatgaccatt ttctttgatc cactgagcta gttcgatgat tgccgggttt
      841 cttccttcat tcgaaagaag aagaaaaatg tcttctgatt tgacagaaag ctgatcaata
      901 attgcctgtc ctgcaccttc tagcgtttca tagacacctc cggctggatt ttcaatcaat
      961 atacttggta caagatccgg ggtttgatcc caaaattcaa atgctacacc acttagtgtg
     1021 cggctagcat atatctgcaa tctaccacct tgattaattt gtttcgcgat ccaagtgcca
     1081 gcttgaagca tcagcggctc ttctatcctt aatttctctt ccaattggtg ataatagtca
     1141 aaataacata aactcattta tctctcccgc ctagctatac ttgacatgaa tagaaacagc
     1201 tgcctaatct aaggaagtac ataaaaaaac agtagttaga cagtaacaca tgtggtcttt
     1261 gctgtttcaa acacaaaaaa ggcattgaac gaatacgccc aataccttga catagcaaat
     1321 aaaacaacgt gcagaccatg gaaaatatct acataggggt agaattttca ccctagatta
     1381 ggtacaataa attaggtcga tgcactgcat tgactatggc aaaatgatcg gtcagggtgt
     1441 atgtgtgtga ctggtcattc cctgattctt agcgccaact aagggtcagg gagccttttt
     1501 ttattcagct gtttctatct gaatttattg taagtaatct cttatccaag tgcaagcaag
     1561 aaaatacaaa aaaacattgg tatgatttat atatatataa ataacataaa aaaaggaatg
     1621 gcttatcccg atacaacaag cattccttta aaaaagattc ttttatataa gtgaaaaaag
     1681 cttttttcca ccaattaaat aaatctctca tctcaatagt ttatccatta ttttatcttt
     1741 ttttgcgtat acctactaaa tattaccgtc ttcttctcgt tcttctactt tgttcgagag
     1801 aatctgtact agaaaaagta gttgtatgtc taccttttct gcctatccga gactttcttt
     1861 tcatatatgg gatataaatg attagataca gtacagcaaa aaataaagca aatacgcaag
     1921 cttcccaact acctaacgcc aattcaacca tcaaggtagc aaccccaacg gatgctgcat
     1981 accagataaa aatcagaaac gtttcttttt ttctgaccat gcgaaacatg ataaatagac
     2041 taataagcaa tagtggcaac acaaatatcc aattgcttcc ttccatcagc cacttgagta
     2101 tatcaagcag cgactgtgca acagcgacta attttcccat agtgaacaca cacctttttt
     2161 tataattaaa aaattcgcct ttttattcta ctatgaatct tctggcttgg ctttcatttc
     2221 tcttatgtaa tcattttctt ttatacaact taaaaaaaaa ttaaaccatt agcataatat
     2281 tttctgaatc tattcacgaa agtctttttc tatctttcgt tttccacgac tcaactgatc
     2341 tagagtcaaa aaactaaaac gacagttgcg caaatgacgc acaagctgcc gctttaataa
     2401 caaatagcct ttcattctca gcaggccact tatttccagt taactttctg ttcttagctt
     2461 tttactcaac tggataatat atgcacttaa tgaagtccca atttccgaat gttgaagtcc
     2521 atattcaata tttgtcttca tatatcctaa cttatcgcct acgtcgtatc tttttccttt
     2581 aaactctctc gcatagaccg cctctgtctg gttaagagtc tgaagtgcat ccgttagctg
     2641 tatctcgttt cctgctcctg gttcttgagt ttctaatatc tcaaatattt taggagtcag
     2701 tagataacgt ccgataatgg ctaaattact tggtgctttt cccatttcag gtttttctac
     2761 aaaccctttt actctgcaac gacccttttc gctatctgtt ttaggatcaa taattccgta
     2821 tttagatgtt tcattttctg gtacacgcat gacggcaaca gcggaagctt gtgtttcttc
     2881 ataatccatc atcaattgtt gagtcaatgg gatatcatct ttcatcaaat catcccccag
     2941 catgacgaca aacggttcat ttcctataaa tgcttttgct tgaagcacgg catcccccag
     3001 tcctcttgga tgagattgac ggatgaagtg aagattgact tgagtcgttt cttcaactaa
     3061 agcgagtaat tctgtttttt ccttttcccg caaattgttt tccaattcga tatttgcatc
     3121 aaagtgatct tcaatgggtc ttttttcttt tcccgttacg atcaagatgt cttcgattcc
     3181 cgaatccaat gcttcttcca caataaactg gatcgttggt ttatccacga ttggaagcat
     3241 ttcttttgcc atggcttttg ttgccggcaa aaaacgtgtt cctagcccag cggcaggaat
     3301 gactgctttt ttgaccttca cttgctgttc ctcctaaacg acgattaact attgatcatc
     3361 tatttaacga agagaaaatt cattctccat ttttccgtca cgtaacatga tttcttttgc
     3421 tgcttttttg atatcttctc cattatacaa aacattatag attgtttgag taattggcat
     3481 ctcaacacct agctgttgag ctagctctac tgctgctttt gtcgttgcca caccctcaac
     3541 gaccattccc atgttttcta gaacttcttc cagcttatgt ccctgtccta acaagttacc
     3601 ggcacgccaa ttgcgagaat gaacacttgt acaagtaaca atcaagtccc ccacaccact
     3661 caaaccgata aatgtcagag gattggcacc catcgcgaca ccaagacggc tgatttctgc
     3721 caatcctcga gtcatgattg ctgcttttgc atcatctccg aatcctaatc catggatagc
     3781 gccggcacca attgcaatga tatttttcag tgctgcacca gtttctacgc caatcacatc
     3841 attatttgta taaatcctga aataatcatt catgaacagt ttttgtacat aggctgctgc
     3901 tttttgatca atacttgcag ctgtaattgt tgtgatatca tgtactgcca cttcctcagc
     3961 atggctagga ccagataata caacaattgc ctgtcttttt tcttctggaa tttcttcagc
     4021 caaaacttct gagattcgtt tatgcgtatc ttgttctagt cctttacttg catgtataat
     4081 gattggctta gtattcattt taccaataag ttcctgtgcg actgaacgaa tcgcttttgt
     4141 tggaacaaca aataaaatag catctgcgtt atccactgct tctgccaatt ctttatatcc
     4201 gataatcgat tctgggatcg tcaaatcagg taaaaaatgc tgatttgtat gatacttatt
     4261 gatttcatca atctgttcag gtacatttcc ccaaatacgg acatcatgcc cgttttctgc
     4321 caatgtttgt gctaaagcag tgccccaaga tccaggacca agaactgcga ttttttgttt
     4381 catggatatt cctccaaata aataattgat aatttccatt atagtataca tttcttaaag
     4441 ttgggactaa tttccattgt ttttaagtgt ttgtttactt cttttatcgt ttttacttga
     4501 aataatcaat gatatgttac aatagtctac attttatttt tacactcgtt atgctttgct
     4561 tgttcctaag aggaagcagt tttgacaatg ttactaccag cattactatt aggaggttag
     4621 gaaacttctc ctagtgagta ttgatttaaa atacataaga gacagattga acatttctaa
     4681 atctgtcagg tcctgcaacg gacagattgt ctctgttgac ggttgacata ggaacttttg
     4741 ttttagtcaa cattctggat acaaaacgct atgtaaactg gcgcaactcg ttgtacttgg
     4801 acttttacta cggatccatg caacaactaa atagtactat tgcataacaa aaaatggttg
     4861 gcacccacat gtcccattaa acagattata agttgaactg tagataatgc aaaaaatgtg
     4921 ttttataacg taattgatgc caatatttta aaaaaataaa gggagcagtt atcgctgctc
     4981 tctttatttt ttatattctt tttatccagt ctatcctaat aatcaaactg acgatagtag
     5041 cggcgtatct ctaatggatg gcagttcaac tgctccacat gagcatcgat gcgttgtgtc
     5101 actacatgca tcaataagaa agacaaaaca cgtccgcgat atttttcact gataccttct
     5161 actggatagt cttttgtgtc tatcaatgta taattgctgc aaatttttgg caaaagttta
     5221 gccacacgtt cagataacac tctctgttca tcttcgccta aaaataatgt gactggggtt
     5281 gtttcttcta cgatctctaa cgtcccgtga agaaactcgg cagcatggat agatttcgat
     5341 ggaagccagc tttgttcttc ccagtaacac atggcatatg aataaacagc tccccattga
     5401 ttccctgctc caataaaata atgcatacta tcacgtcgat gtttttctgc aaatgataag
     5461 ccaaatgcat ctgctttttt ctctgcttcc actaaccctg ttggtaaata acgttcgagc
     5521 tgttcatagt attctgaata agcttcgaat tctccattca aatacatcaa tcgatctgct
     5581 gccataaaaa atttgatttg ttctgttcca ggagctggat aagtgaccac aaaatcgcat
     5641 agctgagaca acttactgtt cgctttatcg ataaatccaa tcagtgtcgc tcctactttc
     5701 ttgatttgtt ctactgcttt cactacttct tgagttgtac cggtaacaga ggacaaaata
     5761 acgatagaat cttttgttaa tcttttgttt ccagtagtgt aatattctgc agcatgctgt
     5821 acaaagacag gcaagttgct tttcccattc atataagtga cagcttgcat cgaggaagca
     5881 tacgttccac cgattcctag ataatagaca gcgtcaaatt tttccgcata aagtttatcg
     5941 atgatttctt ctacttgcgg acgtaaagct agtgcgcctt ttattgcttt gatttgttct
     6001 tcttcattga atttcagcat gatttccacc tcttataatt tacttttcaa gactgtatca
     6061 aagtcttcaa aaatcttttt gttcaagtca atacctttag ctactgcggt tttataagcg
     6121 aatagttgaa acggaacgac aagcgctaat acagacagat attcatcaca ttctattgct
     6181 aatccaagtg ttttctcgtt tcttgctttt tttgtggtaa tggtgagagt ctctccaacg
     6241 taccgactca tatatctttg caacttttgc gaacgttcct tatttacact ttccccttca
     6301 ataaagaata gcaaatgcga agcatctgcc tccaggtatg ggccgtgcat ataagcttct
     6361 aactcaaatc cttgtgacgg aacgcggatt gtttcagtca atttcgtctc tgcttcttta
     6421 gctgttcccc agtttggacc atatccaatg gtgacgaaac gctgtgctaa acgaaataaa
     6481 ctttgatatc catcaaaaaa ttcttccgtt ttttgaataa tcgctggtaa atggttgatt
     6541 attttgcgca actgttgcat gtagtcttgt tctatttttt tgctgatttt atttttactt
     6601 attccaattc ctatccctaa gagtagtaac tgtaaaacag tcgcagaata gccttttgta
     6661 acgaagccta ctgattctac cccggcacct aaatcaataa tttgtgcagc ttctaaagca
     6721 agtggacttt gcacgtcatt tgtgatagca acaacaggta acccttgttt ttgtatcatt
     6781 tttactgctt caacagtaga agcacttttc ccgctttgtg acacagcaat cacagtatcg
     6841 attgaaggag aaagttttcc ataattgaaa aaataaaaag gttcttgaat atcgacagta
     6901 agatcaccat aagattccaa tgctggcttc gctgctaaac aagcgttata agatgaaccc
     6961 gttgctaaga tcagtaaatt cactgttttt ttcatatgtt ctcttgtcga aaaatcattc
     7021 tttttcaaga tcgtacttag tacttccttt tcttcataga tataatcttg catcgtaaac
     7081 attttctctg ctcctttttt aaaaaatccc tatccacgaa ccaaaaattc caaagaaagc
     7141 tagtccgatc aagatcgtta atggtttcac ttctttcttc aatagataaa acactatgcc
     7201 aaatgctcca agacataaga tatttggaac gatatcatca aaaatacttt gaacagtcac
     7261 agcattttct cctgaaccga tttttaaagg aatattgatg gtgatcatcg tggcagtcat
     7321 tgctccaacg accatcagtc caataataga cgcgcctaat gtcaaacttt ccatcatacc
     7381 gtttgcctgg atctttttca aaaaacccgt tcctaagcga tatccccaac ctgttgctag
     7441 atagcgaaac agaatgtgcg gaatattgaa aatcaaaatg aacaagatag ggcctaaaat
     7501 atttccttgc atggctaaag aggtacccac acctgtggca atcaatcgca aagttcccca
     7561 aaagaaagaa tctcctaacc ctgcaagagg tcccatcaaa gatgttttga tactatcgat
     7621 cgcagtcaca tcaaattcag gatcatcctt attttcttcc tccattgcag ccgtgattcc
     7681 taaaatcagt gtaacgatat gtggggtcgt gttaaaaaac tctagatgcc gtttcaaagc
     7741 tgctgccatt tcttctttcg actgatataa ctttttcaaa atcggaatca ttgcataaac
     7801 ataagccata ttcatctgac gttcataatt ccaagaaaac tccatttgaa aagaacgcca
     7861 aaatacgtga tttagctctt ttttcgttat tttgctgttt ttgatctcag aattcttcat
     7921 cttcttctac ctcccctgca gttgtttgaa gtggtagttg acggacattc ataatattga
     7981 ctaccacaac tgctaaaatc gcaccaaaaa tagctactcc ggtcacagga atctctaagt
     8041 aagaagctat agcaaaacct aagaaaaaat atggtgcaac ttgtttgttg atcagcaaac
     8101 gagcaagcat cgcaaaacca agagctggaa tcaaccctgt agctactgac aacccctttt
     8161 gaacgaagtc aggaatcata tttaatagat ttccgatcgt attgcttccc accatataag
     8221 aaaccattac cacaacacca agcatcaagg aaagaccgat accggcaagc aagtgcatat
     8281 gctcgactcc tttataattt ccttcttctg cataattgtc tgctttatgg ttcataattg
     8341 gaatcaaaag ccctaagtaa atatttttca atatcaatgt caacgtagca atcggcaaac
     8401 ctagtaaaag cgcggtttct gtaccggctc cagctgtaat agcaaaagcc gtccctaaaa
     8461 tcccaccggt cacaacatca ggtggaatcg aagcacctac tgagaacgat ccgataaatg
     8521 ctaactctaa agttgcgccc ataatgatcc cagtttttac atcacctaac acgattcctg
     8581 taaacagccc cgtcacaatc ggacgagaaa gcaacgatgt ccctagtgca tattctgatt
     8641 gtgcgacaaa tgcaacaatt cctaataaga ctgcttgtac aatcattgag gttcttcctt
     8701 tcttacaaaa cttctcttac atccactttt ttatctgctg gtacttgacg gatttctact
     8761 tctatttgtt tgtcaattaa tcgtttcaag cgttcctcct cttctggtaa aatatttacc
     8821 gcttttccga tgctgcgagt accaggtttt gccttgatcc ctcctaagtt gatggttttg
     8881 atttctggat acgcttctgc cagcttatat gcatcctcga tcgattccac tacgatgaat
     8941 aacttatatt tatctgtcac cccgcttttc aacgcggcaa tcgagtcatc aattgatttg
     9001 atcactagtt tgactccttg tggcttggct aatttgatcg ttgtctttcg tatctcattc
     9061 gtaggtacat catcattagc aatcaaaata cagtctgcgc ctattgtttg tgtccatgaa
     9121 aaagctactt gtccgtgtaa taaccgatgg tcgactcttg tcaatacaat catttttctt
     9181 cctcctaaaa ttcgtcttct tctattttct gattgagccg ctcgttacaa aactggatca
     9241 ttttttttga atcagttagc acctgctgga tcaaaacagt tgtctctact tcagcgtcca
     9301 accgagatac tagctcaatc aatagtggca aattcaatcc ggcaacgaga tagacatgat
     9361 cccgattgat atattgtaag aattcgttgt tgacacttcc gccaaaaaga tccgtcagaa
     9421 caatgatttc tttatctttg tacctcataa aaagctgcct tactgtttcc gctaaatcaa
     9481 aattctcatc agtatagcaa tcgaatacag taatagaatg atttttccca tagatcagct
     9541 ctaatgaatc taatatccct gaagcaaatt ttccatggga agctaagata atttctctat
     9601 ccactttttc atctcctctt ttcacttaca catactaaaa aagcaagttg catgccaaaa
     9661 ttagtggcaa caacttgctt atgttcaaaa ttcttcttct atcgagagaa actctgtatc
     9721 ttcactcaaa atatcataga tataggcaat ctcagaattg gggatcatga cactataatg
     9781 ctcttcaatg acactaaacg cagatttaat agcagataac ccttcttttt gacactgctt
     9841 ccatttctct aatccttgat aggtttcgat tggcatttgt cggatcaatc gttcaatgag
     9901 acagctcaca tggacataca acgctaattt tttgggattg ctgatgcttc gattcaactg
     9961 cacctctaat tctctcataa aatgatcgat ttctcccatc accttctctg tatctagaat
    10021 agtcacggaa tccagtactt tttccaatga aaaattacga atgatgcgct gattgaatat
    10081 ttccttctct gaagcattca tagtagtgtc caaccattca gctagtacag acatcttttc
    10141 ccccgagatg aggtcttcta atgaaagata gtcgatattg gtgatatcag gatctgtggt
    10201 gccaatcatt cctacgactt cgtatatgga aaataatggg tcactgtttt tcttatcttt
    10261 taattgctga tattcatatg ggatgatttt caactgacaa gccgtaggta agcttttttc
    10321 tagcagttca cttaagtgga ccgccgtacc gattccagtg aagcaagtag taatgagtgc
    10381 tttgggtttg ttttcctctg gatagagcag tcgccattct ggctggatct gtcgaacagt
    10441 ctcttctgct atctcttcta atgatacatt tttttgcagg cattccccta ctgtgattgc
    10501 taaaggtgtc gtcacattat tcaaaatcaa aagcggtacg gataactgtt ttttaaaaaa
    10561 ctgatggatt tctttcagag atcccatgtc tactaatatg atcaatccat ttgaaacatc
    10621 gctgttttcg caataatcaa ggatttctga agcaatctgc tgtggtgtga catctagtgg
    10681 catatcaaat gattcaaata gatcctcttg taataaacga tttactacat ttgccatact
    10741 gctagcagtt gcataaccgt gagcagcaat catcgctttt ggcagtcgtt tttcttttga
    10801 ccatttcgct ttttttagat agatcgtcag taaaatccga tccatacttg tgtcttcaat
    10861 atctaatttg atcttactta attccagaat tcgttggaca tagtgataac tagatggata
    10921 agactgagaa acttgttgtt ctaattcttt gattagttgg ataatatcat gttcttccgg
    10981 taaccatttg atagtgcttc gctgatagag atagtaactc aaggcataga cactgtttcc
    11041 atcgaatttg atttgatagg cagtttccat ttgtcgaaag gtctctcgga tagattgtgt
    11101 ccaataaacc agcagctcgt gtttttcttg tctactggtc tcaaacagca aaaaatcaaa
    11161 taattgaatc acttcttgct ttaattttcc ttcgcaagaa tatagcagac agttattttt
    11221 cttgaaatca attaggattt gctcaaaact tttaacgatt cgctgctgtt cgggctgttg
    11281 cttctccatt aattgctcta aggtctggtc ttgcgtaata tagattcctt gctgtgctgt
    11341 atttttagta ataggctgcg caagtagttc tttttgcaaa tgatggatcg tgacatggat
    11401 ttcaggctgt tcacgctgtt cagcatatgc ttttgctgct gaaactttga cgatattttt
    11461 cagctctcct atgtttccgg ataatttctg acttgttaaa agtgacaaag ctggtccact
    11521 gactgacaaa gggctcccca tttttctttg ttcttcgaga aaaaaagagt aaatcagttc
    11581 tagccgttca ttacgactac gctgattaag tgcaggtagt tcgattcgga taggtattct
    11641 tcgaatgaaa gttgttaaga aatgactagt aatctcttca gtcgtagcaa aaaagagacg
    11701 tgttttgatc cggcgtgaca aattaggttc tcccatacga taaatcacac cttgatcaag
    11761 ataggtgaac agtttttcct gaccttctgg tgttaagcga tgtacctcgt ctaaaaacaa
    11821 gatcccacca tctgctgctt caaaagcccc ttttttattt tcttctgcac cagtgtacgc
    11881 tcccttaaca tgtccaaaca aattgctagt caaaagttca ggattatctg catattgtgc
    11941 acaattaaaa gtgatgaatg gtgcagaatc ttctagcaga tcatgaagca gacaatactg
    12001 atagaccaaa ttaactaaat aacttttacc tgtgccactt tcgcctgtaa tcaaaagtgg
    12061 taatccgcca tctggatagt aaagagctgt tttgatttgt tcgatacttt ctttcaaact
    12121 ggcgtcgtat ccgatcataa aagagaataa gtcttttggt tgcgcgaaaa aaggctgttc
    12181 ctctttgaga tcatcgatag aaaaataaaa attcgtgcgt aacttaaaaa attgtttttc
    12241 aaaagcttct ttgtggaaat aaatcactgg tcgagaattg attttgacta gtagttgctc
    12301 atcatttaac tggttcaaat aatgactgac tgtgtttctt tttaccccaa aatgatcagc
    12361 taacctttgt gctgtaaaga cctcgttcat atgttctaaa tcgaaaaagg ctgtctggtt
    12421 ctctaagtaa cataaaattt ccttcttcaa caacttattc acccctcctc catcatagaa
    12481 aacggattca ttttgtcaat aaaatcttta ataaagaatt gaaaaatata tcttattata
    12541 gacagcagcc tacttatccc ttataatttt tattctaaaa aacgtacagt tccttccagt
    12601 ttttatactg gaatttcaac atatgaaaga ataaggaggc tatgactatt caatgaaatc
    12661 ggataaatat aaaaacagga aacatacttc ctggaaaact tttcgagaaa tcatcggatc
    12721 ttatctcgct gtagttgtat ttttgccttt gctttatatg gctatgacag aacaaactcg
    12781 ttttattggc gtagatacgc aatatatagc cgaaacagga tttttattca tctttatctt
    12841 gatttttgcg ttctataaat ccttccatac aaaataagat tcacagattt caactttcct
    12901 gtctgttttt agctattaca aatccttata tgtggtataa caacaattta ttggcataat
    12961 gaggaaaaac gagttatgat gctttcagag agtaaagagg tactgttgtc accatccttt
    13021 ttattgatta cgtacaccac tcttagtttt ttcccattga ttacgaaaac aaggtagaaa
    13081 cattgatgtt cctaccttgt tttctttttt tattttcaga tcaaaatctc aagtggcttt
    13141 tgacttgatg tcgggaggtt gtcttcgttc catcaaacct gatagaatct gcgccaaacc
    13201 atagttttct ccactattat ttattcctct aagatagtac ccacaataaa cgaataaata
    13261 tttttctcat tttcatactc cttctttgaa aatcaattag atttctctca acccactttt
    13321 ttacaaaaat tacgtagcaa aaaagattgc aagaacaaat taaaaaagaa gtaaatagag
    13381 tttcatctat aaacatttac ttgatatatt ttttatgcag aattcattta tagaaaaatt
    13441 aagtaaaata gacgttccta tgaatgaaga gactggcatg ttttctcatt ttcttttttt
    13501 taaaaaaaat agtctattca atttctaaag cttcttcata ataaaacttt catttatgaa
    13561 aaggcttgtt ctcttttcat tctaaatttc ctaagctaca atgtggtagt acttgttttt
    13621 tcaattgtgg acaaataaat aataggagga atcatatgat tcagttatta cgttatgcaa
    13681 aagactatcg taagcaaatc attttgggcc cgttcttcaa atttcttgaa gctgtcttcg
    13741 aacttgtcct gcctttaatg atggcttcct tgatcgataa tggactaaaa atgaatgacc
    13801 gaggaaaaat cattgaaatg ggcttatgga tggtcgctat gtctgtgatt ggtctgattt
    13861 gtgctatcat ttgccaatac tatgcttcag tagcttcaca aggatttggt acagagttac
    13921 gtaatcagct aatcaaaaaa atcaatactt tctctcacaa cgagttgaat cattttggaa
    13981 cagatacctt gatcacccga atgacaaacg acatcaatca gcttcagcta gctttagcaa
    14041 tggtcattcg tttattgatc agagcaccgt ttttaagtat cgggtcagtg gtcatggctt
    14101 ttgtgatcga ctgggaagta ggtctgtttt tcttagcatt attgcctatt ttctcaatca
    14161 ttttattttt tatcatcaaa aaaaccgttc ctctctacca aaaagtgcaa gaaaaactag
    14221 atcagctcaa tgaacacgtt agtcagaatc ttagcggtgt tcgtgtcatc cgcgcatttg
    14281 cgcagacaaa aaaagaaaca gagaagttcg ataaaagcac aaatgatcta gcgaacaatt
    14341 atttacgtgt ttccaatatc tctgccctat tatcacctgc tacaaccttg atcatgaatg
    14401 tcgggatcat ctgtttgctg acagttggcg ggatcaaagt aaatattggt agcttgcaac
    14461 aaggacaagt tcttgctttg atcaattata tgaatcaaat gcttttggca ctgatcgttg
    14521 tttcaaacct cgtcgtgatc ttcacacgtg ccgaagcttc aggaaatcgg gtgaaagagg
    14581 tgctagacac agaaaattcg attcttgaag ctgaggtcag tactactccc gatttttctt
    14641 ctgaagcaat tatcgctttt gaccatgttg acttccgtta tactcctgat tctggtcttt
    14701 ctctccaaaa tattacattt cagctgaagc gaaatacagt ccttggaatc attggtccaa
    14761 ccggaagcgg gaaaacgact ttgacacaat tgattccgcg tttctatgat gtcagttccg
    14821 gtacagttat aatggacgga atggatgttc gttcttggca gctggatcat ctccgtcagc
    14881 aaattgctct tgttccccaa acttctgtac tatttaccgg gactattcgt gaaaaccttc
    14941 aatggggtaa gaaagacgcc acagaaaaag aatgttggga agctctgaaa atcgctcagg
    15001 cagaagaatt tgtccgtcag cttccaaatg gtttagatac aaaagtcatg gaaaatggga
    15061 aaaatttctc tggcggacaa aaacagcgac tgacgattgc aagagctttg attgccaagc
    15121 cagcattact gattttagat gactctttaa gtgcgttgga ttatcaaaca gacttggatt
    15181 tgcgtaaggc gctacagact tatcttggca gtacagtgat tattatctcc caacgtgtcc
    15241 gctctattca agaagcacat catatcttag tgatggatca aggtaagatt gctgctcagg
    15301 gtacccatga agaattactt gctcaatcag cagaatatca ggaaatcgtc gcatcacagg
    15361 aggaagaata gttatgaaag taaaaaaatt atccttgcag acgctccgcc gattcattcc
    15421 ttaccttact gcctatgcaa aagacatttg gctagctgtg atactaggaa tcatcaatgg
    15481 gattgcaaca gttgtgatga cgttacaaat tggtcaaagt atcgatcaaa tgattggaga
    15541 aggacaggtc cgcttcaatc gactgttcca tttacttatt ctattcggtg gtatcgtttt
    15601 aatcaacgta gtcagtcaat ggctcatcca agtgttaagc aatcggttag cttacttatc
    15661 cgttgcaaaa ttaagaaaag atgcatttgc tcatctgaat cgattgccac ttcgttatta
    15721 tgatcaaaac tcccacggaa atatcgtcag tcgatttaca aatgatatgg acaatatttc
    15781 cattgcaatt tctgcggcct tcaatcaatt attttctgga gtggcaatca tcattctttc
    15841 gtttattttt atgatgcgtc taagtccact tctgacattg gtcgttcttt gttctacacc
    15901 aattattttc cttgtgagtt ggatcgttgc tcgtgcttca caaacaaatt tcgatagaca
    15961 gcaaaggatt attggggata tctcgggctt tgtgaccgaa cgaatcggta accagaaaat
    16021 cgtgaaagct tttcagcaag aagaagctag tcaacagcaa tttgaactgc taaatgctga
    16081 tctatatgaa aaaggacaac gggcacaatt ttcttcttcc ttgacaaacc cgtcttctcg
    16141 ttttgtagat caccttgctt atttatcgat tggtttagtt ggcggcctat tggcattgaa
    16201 gagtggttcg tcaatcactg ttggtgtgat ttccagcttt acgatctact caagtcagtt
    16261 ttctaaacca tttatcgaac tttctggaat cacgacacaa ctgcaaaccg ctttttctgg
    16321 tctagaacga gcatttgatt tgatcgatca gccagaagaa aagcctgatt tgccagatgc
    16381 ctatgccttg gaacccaaaa atatcaaagg aaaagtctct tttgatcatg tttctttttc
    16441 ttatgacccc aagcagcgtt tgatcgaaga tttcaatttt actgcttatc caggtcaaac
    16501 cattgctata gtaggaaaaa caggggccgg aaaatccaca cttgttaatt tgctgatgcg
    16561 tttttatgac acaacaaaag gaacaattac agtcgatgac catgacatcc gctctatcca
    16621 acgtgataca ttacgtaaaa gttttggaat ggtgttacaa gatacttggc tatttgacag
    16681 tacattgcga gaaaatcttc gttttgggaa tccggaagca agtgacgcag aaatcaatga
    16741 tgccctaaaa gcctcttata tgtatgaatt tgtagaacgt ttgccggaaa aattagatac
    16801 taagattggc ggtcaagggt taaagatatc agatggacaa cgccaactgt tgacgattgc
    16861 tcgaacgatg atcagtaatc cccctatgtt gatcttagat gaagctacca gctcagtcga
    16921 tacattgaca gagaaaaaaa tccaacaagc cttcttagca atgatggaag gaaaaaccag
    16981 ttttgtgatt gcccatcgcc tgtccacaat caaaaatgcg gaccagatat tagtgatgga
    17041 tcagggagct attgtcgaaa tgggcaccca tgatgagctg cttcaaaaag atggttatta
    17101 ccgacggctc tatcaagcac aattcacagc acaataaaaa caagcagtct tctgggatgg
    17161 gaagactgct tgttttttat ttagcgtgga tcgctaaact tcttaaaatt tttttgtaag
    17221 gaatactacg tcctacgtaa taaatggcaa ttgattgaat cggtaaccat attactgttt
    17281 ttaacaggcg gggcgcccaa acgacccagc tgaacaatgg cacatggtac atcaacgcaa
    17341 gccataatgg tgtcaaaaat aagttgatga tcagcgtgac actaagcgta gccagaatgg
    17401 catttttcca agtgatctct tttcgataga aaaagaatcc gtagattgct ccttcaataa
    17461 atgcattcaa tgtaaatcca ataaagaatg cagatttcga gaagagggcc attcctacta
    17521 aatcagctaa aactgcgcct atccctgacc aaaaaggacc aaaaagaatg cccatgatca
    17581 cttgtggaat aaatgtgaca ctgattttaa taaatggggt ctcgattgct accagtcggg
    17641 acaaagtgac catcaatgca atcaataagc ccataatagc aatcatacgt gcgtctaacc
    17701 ggtgtttctt catttttagc atctccttta agagctgcta catcgtatca tgcagcgaat
    17761 gcgaaaataa aaccgcgaac attacgtcct tcgtccaaga ggcaacatcc catcctctta
    17821 gcacttaacg ctttattttc tactctgtat tatttttggg atcttttccc acagaaacta
    17881 tagcatattt tcacatttac tgcaaatacg aaaaactaat attattgttt atattatcca
    17941 atacgttcgt attatatcgc atattatcag tttgtttagc ttttatagct acatataggc
    18001 gaacattaaa cgttattttt ccatacgctt atccatcaaa atgaaagtgg atgcttgtct
    18061 atttcatgga cgattcttcg aaaatctagg aagccggctt ccagtcctct tagtagcacc
    18121 tcagctgttc cgatattcgt agctaacgga atctcataga catcagataa acggataagt
    18181 gctgttacat ctggttcatg gggctgtgca gccagcgggt ctcgaagaaa aatcaccaaa
    18241 tctaactgat cctccgaaat catggctcca atttgctgat ccccgcctaa cggtccggat
    18301 ttaaaccgat ggatcggcaa gccggttgct tccgtgatcc tctgcccagt cgtcccggta
    18361 gcaaaaagtt catgtttttc caatattgtt ttatacgctg ttgctaattt caccatcata
    18421 ggtttttttc ggtcatgagc gatcaaagcg attttcataa gagacactcc ttttgatatt
    18481 gttaacatac ttatttactc cagtgtatca gtttttattt cttatggata tttattaaa
//
LOCUS       DAIGWC010000059        18530 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.060, whole genome shotgun sequence.
ACCESSION   DAIGWC010000059 DAIGWC010000000
VERSION     DAIGWC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.060"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            125..772
                     /locus_tag="NOB74_002048"
     CDS             125..772
                     /locus_tag="NOB74_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCI1221217.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    901..1117
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1165..3810
                     /locus_tag="NOB74_002049"
     CDS             1165..3810
                     /locus_tag="NOB74_002049"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HCI1221218.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4120..5433
                     /locus_tag="NOB74_002050"
     CDS             4120..5433
                     /locus_tag="NOB74_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HCI1221219.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5423..6076
                     /locus_tag="NOB74_002051"
     CDS             5423..6076
                     /locus_tag="NOB74_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI1221220.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6131..6823
                     /gene="radC"
                     /locus_tag="NOB74_002052"
     CDS             6131..6823
                     /gene="radC"
                     /locus_tag="NOB74_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCI1221221.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6973..7173
                     /locus_tag="NOB74_002053"
     CDS             6973..7173
                     /locus_tag="NOB74_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI1221222.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7427..9106)
                     /locus_tag="NOB74_002054"
     CDS             complement(7427..9106)
                     /locus_tag="NOB74_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCI1221223.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9108..9320)
                     /locus_tag="NOB74_002055"
     CDS             complement(9108..9320)
                     /locus_tag="NOB74_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HCI1221224.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9713..11443
                     /gene="efrA"
                     /locus_tag="NOB74_002056"
     CDS             9713..11443
                     /gene="efrA"
                     /locus_tag="NOB74_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HCI1221225.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11440..13200
                     /gene="efrB"
                     /locus_tag="NOB74_002057"
     CDS             11440..13200
                     /gene="efrB"
                     /locus_tag="NOB74_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HCI1221226.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13295..13492
                     /locus_tag="NOB74_002058"
     CDS             13295..13492
                     /locus_tag="NOB74_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221227.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13645..14130
                     /locus_tag="NOB74_002059"
     CDS             13645..14130
                     /locus_tag="NOB74_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HCI1221228.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14234..14827)
                     /gene="clpP"
                     /locus_tag="NOB74_002060"
     CDS             complement(14234..14827)
                     /gene="clpP"
                     /locus_tag="NOB74_002060"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HCI1221229.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            15007..15534
                     /locus_tag="NOB74_002061"
     CDS             15007..15534
                     /locus_tag="NOB74_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221230.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15625..16362
                     /locus_tag="NOB74_002062"
     CDS             15625..16362
                     /locus_tag="NOB74_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCI1221231.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16366..17283
                     /gene="miaA"
                     /locus_tag="NOB74_002063"
     CDS             16366..17283
                     /gene="miaA"
                     /locus_tag="NOB74_002063"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HCI1221232.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17285..18514
                     /gene="hflX"
                     /locus_tag="NOB74_002064"
     CDS             17285..18514
                     /gene="hflX"
                     /locus_tag="NOB74_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HCI1221233.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5991 a         3205 c         4027 g         5307 t
ORIGIN      
        1 agatgcaagc ttttgaacac cgttttattt gtctcacacc cttttccttc ctacttgtaa
       61 ccttgctccc gtgttagaaa catgttacac taaatatgtg aaattattaa caaggagcgt
      121 cgttatgcga gaaaaaacag atacactgcc aaaagcaact gcgaaaagat tacctttata
      181 tttacgctac ttgaagatgc tggatgactc aggtataagt agaatcaaat caaatgagtt
      241 cagcgaaatc acccaaattc cttctgcaac gatccgcaga gacttctcgc aattaggcga
      301 gctaggcaga agcggatatg gctatgatgt cccttttctt atcgatgtat tcaataatat
      361 ccttaatact aaagaagaaa aacgaatcgc attagtagga tatggaaatc ttggcaaagc
      421 attgaaacac aacaatttta gaagaaatga aaatctaaat atcgtgtgcg tctttgataa
      481 tgatccagca ctgatcaatc gagtaattga tggagaaatg atctatccga ttgatcgttt
      541 cgcggagata gccaaagcaa aaaatgtgac agtagcaatc tctacggtac caagtaaata
      601 ttcacaatct gctattgatg aaattgtcaa aggaaatgta accgctatac ttaattttgc
      661 gcctgacaga gtaactgtcc cagcttatgt caatgttcaa tacattgatt tgacaaccga
      721 gttgcagacg cttatttact ttgatgagaa ttactcagaa gttttttctt aggaaaattt
      781 gagtaggctt attgatcttg cgagaactcg tcgtaattct ttcaaaaatt ttttagtact
      841 aaatgaagtg gttttttcac gaccacttgt tgactaaaaa aaaaaaccat tgtagaatga
      901 agcataacgc tgaacaagag gagtaactgg cacattcatt cttagagaga gaactatctg
      961 ctgaaaggtt ctcaatgaca accagtgaag gtagcttggg agtttctgtc ttgaatggag
     1021 tagagataga cgagtcgtga tcgttaactc acttgagagg caataatgat tgattattgc
     1081 aatttaggtg gtaccgcgta aatcatacgt cctagaatac gaaagtattt taggacgttt
     1141 tttagtttaa aggaggaaaa cagcatgacg gaagaaaata acctatcaac aaaatataat
     1201 ccgcaagaag ttgaagctgg acgttatcag cattggttag aacaagattt gtttaaaccg
     1261 agcggagata aaaaagcaaa accttattca atcgtaatcc cgcccccaaa tgttactgga
     1321 aaacttcatt tagggcatgc ttgggatacg accttgcaag atatgctgat tcgtcaaaag
     1381 agaatgcaag gatatgatac tttatggctg cctggtatgg accatgcagg aatcgcgaca
     1441 caagcaaaag tagaagcgaa gcttagagag caagggattt ctcgttatga tctaggtcgt
     1501 gaaaagttca tcgatcaagt gtgggaatgg aaagaagagt atgcgagcca catccgcgaa
     1561 cagtgggcta aaatgggctt atctttagat tacagtaggg aacgttttac attagatgat
     1621 ggattatctg aagcagtacg taaagttttt gttaccttat acgaaaaagg tttgatttat
     1681 cgtggtgaat atatcatcaa ctgggatcct caagcacgaa cagctctatc tgatatcgaa
     1741 gttattcata aagatatcga aggcgccttt tatcatatga gctatgaact agcagatgga
     1801 tcaggcgtag tagaaattgc gacaacccgt ccagaaacga tgttgggaga tacggcgatt
     1861 gctgttcatc cagaagacga gcgttatcaa gcgctcatcg gcaaaaaagt gattctacct
     1921 ttagtcaata aacaaatccc aatcattgca gatgaatatg tagatatgga attcgggaca
     1981 ggtgtagtaa aaatcactcc agcacatgat ccaaacgact ttgaggtagg taatcgtcat
     2041 gatcttccac gcgtaaatgt tatggatgat gatggtacga tgaatgaact agcaggaaaa
     2101 tatgctggaa tggaacgttt tgctgctcgt aaagcaatcg tgcaagatct gaaagaaatc
     2161 ggtcgattga ttaaaatcga tacgatgatc cacagtgtgg gtcattccga gcggacaggt
     2221 gtcgttgttg aacctcggct gtctactcaa tggtttgtaa aaatggcgcc gttagcgaaa
     2281 aaagccattg ataaccaaga aacagatcaa gcagtggaat tcttccctcc aagattcaat
     2341 caaacgtttt tacgttggat ggaaaatgtc catgattggg taatctcacg acaattatgg
     2401 tggggacatc aaattcctgc atggtatcac aaagaaacag gtgaaatgta tgtagggatg
     2461 gaagcaccag cggatagtga aaactgggta caagatcctg atgttttaga cacttggttt
     2521 agttcagctt tgtggccttt ctcaacaatg ggctggccag atacggaaag cgaagattat
     2581 aagcgatact tccctactag cactttagta accggttatg acatcatttt cttctgggta
     2641 agcagaatga ttttccaaag cttggaattt actggcgaac gtccatttga gaatgtcttg
     2701 attcatggat tgattcgtga cgaacaaggg cggaagatga gtaaatcatt aggtaatgga
     2761 atcgatccga tggaagtaat cgaaaagtat ggagcagatg ctctccgctg gttcttatcg
     2821 aatggttctg caccaggaca agatgtccgc ttcagctatg aaaaaatgga tgcttcttgg
     2881 aactttatca acaaaatctg gaatgcttca cgtttcgtta tcatgaatat cgaaggaatg
     2941 accgtagaag agatcgattt atctggagaa aaatcagtgg ctgaccggtg gatccttact
     3001 cgtttgaatg aaacgatcga acgagtaact gagctatttg atcgttttga atttggtgaa
     3061 gcaggtcgac aactgtataa ctttatctgg gatgattttt gtgactggta catcgaaatg
     3121 agtaaagaag tactttatgg agatgatgct gtttcaaaac aaaccacccg tagcatctta
     3181 gtccatacac ttgatcagat cctacgttta ttgcatccaa tcatgccatt cgttacagaa
     3241 gaaatatggg aacatattcc tcatcaggga aattctctag tagtggcaga atatcctgtt
     3301 gtacgtccag agtttgatga tgaaacagct tctaaaggga tggaagtatt gaaagaattg
     3361 attcgagccg ttcgaaatat tcgttcagaa gtgaatacac cattgtctaa accaattacg
     3421 ttgctaatta aaacaaacga tgctaaaatc gatcaatttt tagttgaaaa tacaagctat
     3481 atcgaacgct tctgtaatcc cgaagagttg acgatatcaa gtgagatcac tgcgccagat
     3541 ctagcgatgt cagctgttct gacaggtgca gaaatcttct tgccgttagc aggattgatc
     3601 aatattgaag aagaaatcaa acgattagaa aaagaactgg aaaagtggac aagcgaagta
     3661 aaacgtgtcc aaggaaaact ttctaatgaa cgttttgttt ctaacgcgcc ggaagaagta
     3721 gtagaggcag agcgtgcaaa agaaaaagat tatttagaga agcaaacggc tgtcaaagaa
     3781 cgaatcgaaa gtttgcgtac tattcaataa gaatagaaaa agagagtgtg aaatcagcta
     3841 gctattacta aaagctagct gattgaacat cgttacagga aagagtttga gcctcactct
     3901 tagcttcgat tcataaggag atgtgacata aattttgtcg catctctttt ttagtctact
     3961 cttattatgt aggagaagga gggaggtgga tcatgtatca agagtcaata aagtagttga
     4021 taaaatcgtt cctctctctg tttcttttct ctttgtcata cttttatttt tcttatgtgt
     4081 tctatttgtt ataataaaag agaaatgggg gaattgttga tgacgattga agaagcaata
     4141 gaatggatcc atagtcgatt accatttggt tcacgtcctg gccttgaccg agtcgaagct
     4201 ttattagaag tggtagggca tccagagaga aaagtaaaaa cgatccatat cgctggaaca
     4261 aacggaaaag gttctactgt agcttatttg agaagcctat tagaagaggc tgggctgaca
     4321 gtaggtacat ttacttcacc ttatatcgaa acgttcaatg aacggatcgc aatcaatggc
     4381 aaaagcattc cagacaatga tttgatccag cttgtaaaaa aatatcagcc actgatcaaa
     4441 caacttgatc aatttgaagc agtagctggt attactgaat tcgagacatt aacagcaatg
     4501 gcatttgatt attttttgat gaagaaagtg gacgtagcga ttatcgaagt tggcttaggc
     4561 ggcttattgg attctaccaa tgtagctgta ccaatgctga cgggaataac aacgattgga
     4621 cttgatcata ccgaaatact tggagataca attgaagaaa tcgctgcaca aaaagctgga
     4681 atcatcaaac aaggcgttcc agtagtaaca ggaaatattg ccccagaagc ttttactgtc
     4741 atccaacaaa cagctaaagc aaaaaatgca ccgctttatg tatacgggga aaattataaa
     4801 ataaactatc tgcatcctga tgagatgtgg ggagaagtat ttgaattttt taatgaaata
     4861 ggaaagatcc ctcaattaac cactccgctt ttagggcaac atcaagctga aaatgcagga
     4921 gtagccatcg aattgtattt tgtttactgt caattggaaa agctgccttt ccgagaaaaa
     4981 gatgttttga agggattgaa gaaatctcga tggccaggaa gaatggagcg tttgagtaac
     5041 gagccattag ttgttttaga tggtgcccat aatacgcatg caatgaaccg gcttgttgag
     5101 aatttgaaaa aagaattcaa aggatatcaa atcaacattt tgttttccgc cttacgaact
     5161 aaaaatgtta gagaaatgct agaacgattg cagcaagtac caaatgtcca tatttatttg
     5221 acgacctttg aacatccaaa agccatcgaa ttaagtgaag tatcagattt agcaagtgag
     5281 agagtatcaa tcgtttcatt gtggcaattc ggattagcag atatattgga aaagatgaca
     5341 aatgaagacg tattagttgt gaccggttca ctttatttca tttcagaagt tcgccattta
     5401 ttaatacaat taggaggaga tcatgaagta taatgcagtg atttttgaca tggatggttt
     5461 gctgttcgac acagagttag tgtattacga agccacacaa gtagtagcag acaagatggg
     5521 ttttccttat gataaagacc tgtatttaaa attcttaggt gtttcagatg aagaagtatg
     5581 ggcgaattat catatgattt tctcggaatt tggcaaaaca agtgtacaaa gattcataga
     5641 tgattcatac caggaaacgc ttgaacgttt ttcgcaagga gcggtacaaa tgaagcccgg
     5701 tgtgttggaa ctcctctctt ttttagaaga acatcagatt cccaaagttg tcgcttccag
     5761 taaccaacga gcagtcattg aacttttatt gaagaagaac aatctgtttg aacgatttga
     5821 gacgattgtt tctgcagaaa atgttcaacg agcaaaacca gacccagaaa ttttcttgtt
     5881 agctaatcag aagctaggta cagcgaagaa agaaacattg attttagaag attcacaaaa
     5941 tggtatttta gcagcttctg cggctgagat cccggtagtc atggtaccag atctgcttcc
     6001 accatcccaa gaattgatca aaaaaacagc tggggttgtt tcttctttac atgaaatccc
     6061 tgcattgtta aaataaaaat ccatctcttt tcgtatctta ttttagataa gatagaaagg
     6121 agatgttttt ttgggaaaac gattgatcaa agaagtacct actagctctt taccaaggga
     6181 acgtatggaa atttatggcg cggaagcttt atcggatcag gagcttttgg caatcttact
     6241 gcgtaccggt caacaccctt atagtgtgat gtcgattgct ggaaatctgt taaaaacgtt
     6301 tggaggactg gcctctttac gacaggctac tttgcatgag ttagaagaga ttcgagggat
     6361 aggacgcgtg aaagcaatcg aaatcaaagc cttgatcgaa ttaggtcgac gaattcagac
     6421 ggatcatgaa agagcggctc caccggttcg taccagctac gaattggccc agcaattgat
     6481 tctggaaatg aaagatcaca aacaagaaca tttggtttgt atttatttgg acacgaagaa
     6541 tcaagtgatc ttaaaaaaaa cagtgttcat cggttcgctg aatcagtcag tcgctcatcc
     6601 tagagaaatt ttccattatg ctgtacgtta ttgtgcagca aggatcgttt tagcgcataa
     6661 tcatccttct ggtaatgtta ttccatcgca gcaggatatg aattttacca aaaggataca
     6721 aaagtgtgga gaaatgatgg ggatcactgt actggaccac ttgatcatcg gacgcaaacg
     6781 atattttagt ttgagagaag aaggaatgat ggaagagaag taagttgctt tcttgcaaaa
     6841 aaaatgaagc aagtgtacaa ttatattgta attttgtttg ggaatagaag ttgaaacatc
     6901 tgttgcacct ctatcgtaca cgagcaatgt tacaatttaa attagtgctt ttggcacgag
     6961 gaggatatta ttatggaaaa cggaacagta aaatggttca acgctgaaaa aggatttgga
     7021 tttatctcac gtgaagatgg aagcgacgta ttcgttcact tctcagctat ccaaggtgac
     7081 ggattcaaaa cattagaaga aggtcaagca gtgactttcg acgttgaaga atcagaccgc
     7141 ggcccacaag ctgcaaacgt tgtaaaagct taattttatc tgtaaatcaa attgatggta
     7201 gacatcaatt tttacgagag aacaaagcga gtaacaaaaa tacctgccac aagagacaat
     7261 ttctcttgtg gcaggtattt ttttgtatga aaaagtaaat aaatttaaga ggctatgaaa
     7321 gagccacctt gtatcaagga ataagaacaa acaaaaatgg cttctcatgt ttttcatttg
     7381 ttttctctta tattcaggac aaggtgctga tttcataacc tcttatttat tcttcatctg
     7441 gtgtcattac cattggcaaa atcattggat gtctttctgt acgttcgaat aagaaaggct
     7501 gaagcgcgcc agtcatcgct tctttcaatt tatattctga acagtcaggt ccattcaaac
     7561 attctcttaa agcgtggaat aagattcgct gagcttcatt gatcatttct cctgattctc
     7621 gcatgtagac aaatccacga gagagaatat ctggaccagc caagatttct tttttcttga
     7681 tatccactgt cgcgacagct aatacaagac cttcttctga aagcaggtga cggtcacgta
     7741 aaacgacatt accaatatca ccgatcccgc taccatcgat atacacatct ccagccacaa
     7801 aatgcccagc aggacgcgca gaatcgctag ttaacgctaa aacatcgcca ttttccatga
     7861 tgaagcagtt ttctgcagga acacctacat cttgtgctag agaagcatgt actttcaaca
     7921 tgcggaattc tccgtggaca ggaataaaat attttggctt catcaaacga agcattaatt
     7981 tttgttcttc ttgtccaccg tgaccggaag tatggatgtt attgattttt ccgtgaatca
     8041 cttctgcacc agcttcagac agcaaattga tcaaatgatt gacacttgtt gtattaccag
     8101 gaataggtga acttgaaaag atcactgtat cgtctggctg gatttggatt tgacggtgag
     8161 taccattcgc gatgcggctc aacgcggcca tcgcttctcc ttgagaacct gtacatagga
     8221 tcatcgtttc attggcaggc aagcgattga tttcgtgtgc atctacaaat gtgccgtctg
     8281 gaactttgat atatcctaaa cgttgaccgt tgacgatggc attttccatg cttcgtccga
     8341 aaacagcgat tttacgacca gttgccacag cggcatctgc tgcttgctgc aaacggaaga
     8401 tgttagaagc aaagctggca aaaatgatac gtccttcgat ttttgaaaag atcttcaaaa
     8461 tagaatgccc aatcgttttt tctgatttag taaatgttgg aatctcagca tttgtactat
     8521 cagataaaag gcacaagact ccttcttccc cgatacgagc cattttatgc aagtttgctg
     8581 gttcgccaac aggagtgaaa tcgaatttga agtctccagt cgctacgata tttccagaag
     8641 gtgttttcac cacgatccct aatgcatctg ggatactatg ggtcgttctg aaaaagctga
     8701 cagaagtctt tctaaaacgg atgatcgtat cttcattgat ctcatggagc tctgcatctc
     8761 gaagcaagcc atgctcatct aatttgtttg tgatcaacgc taatgcgaga ggaccagcat
     8821 agataggaat atttgcttgt ttcagcaagt agggtattcc gccgatgtgg tcttcgtgcc
     8881 cgtgagtaat caccaaggct tttactttgt gtaagttttg tatgatgtag ctgtagtcgg
     8941 gaatgacata gtcaattcca agtaaatcgt cttccgggaa tttgatcccg gcatcaatca
     9001 aaatgatttc atcttggaat tgtaccccat acgtattttt cccgatttca cctaatccac
     9061 caatagcaaa gacgcctgtc tcgttatttt tgatggaaag tttcatatta aaactccact
     9121 aatgagaaat cagcattttc tttttcgtac tctagatgac ttccttctag aagttgaacg
     9181 aattcaatat tgtatggggt attttcttcc acacgttggc gagcgtctac atcgcttttt
     9241 gcctcaatgt aaagagattt tgtttcttcc cgtttagggt tgcgtacttt tgtttcttga
     9301 taataaactt tatagatcat tgttttgtct cctttatctg cgtaaagcag tgatttagct
     9361 agttgatttt tttagacaac acaaaacgag gggacaagcc acctggtttt tcatatgctt
     9421 tgactagaat actggattcg agtcaaagag acaagcctcg tttttgctta tctgttcgga
     9481 tattttttca accgtacctt ctgtataaaa aatatacaac aattaattgt tattctagca
     9541 taaaacagca aataagtata gaaatcaact agattgaaag aaaaaatcaa tgtttatcat
     9601 cccgctataa tcataatgac ttttttatga gagaagtgtt ctattaatag gctcgttgtg
     9661 ctatcatttt tagtaatgaa aatgtaacaa aagattaaaa ggagatgaga aagtgaaact
     9721 aatgtggcat tataccatgc gttataagaa attcttgttt ttcaatttca tatgcgtatt
     9781 tggttttatt ttgattgaat taggacttcc tacgatttta gcacgtatga tcgatgtagg
     9841 aatccgcaat gatgattttg attatgtgaa gcaacaaggg atatttatga tcgttattac
     9901 tgtaatcggt attattttga atatcttgtt aggttatttt ggttcgagga ttacgactaa
     9961 tatcgtagca gatattcgag atgatttgtt cgaaaagatc caaagttatt cgcatcagga
    10021 atacgaaaat ctaggcgtat cttcattgat cactcgtaca acaaacgatg cttatcagat
    10081 catgttgttc ctgcaaaata ttttacgtat cggttttatg gcaccaatga tgttcattgt
    10141 cagtttgtac atggtcatgc gtacaagtgt gacactcagt ttgtatgtag taggtgcatt
    10201 acctttacta ttattggcag tcgtagcgat tgctaaggtg tctgaaccgt tatctaaaaa
    10261 gcaacaaaaa aacttagata aaatcaacag tatcttgcgg gaaaatcttt caggattgcg
    10321 tgtgattcgt gcattcgtca atgaaaagtt tgaagaaaaa cgttttgctg tagtcaatga
    10381 gaattatgct tctagttcaa aaagcttatt ccgtttgatg gctgttgcac aaccgggttt
    10441 ttatttctta tttaatatcg taatggtatt gatcatctgg agcggggcag tgcaaatcga
    10501 tgcaggcgag cttcgtgtag gagatttgat tgcgtttatc gagtatatat tccatgcctt
    10561 gttctcattc atgttatttg ctagtgtgtt catgatgtat ccaagagcag ctgtttcagc
    10621 tggacgtatc caagaagccc tagatgccaa accttcgatt gtagaagatc caaatggtat
    10681 atctgataca aaaactaaag ggtatatcga atttcaaaat gtaacatttg cttatccagg
    10741 ccattcgcaa gagccagtga tacgaaatgt cagttttaca gcctctccag gagagaccgt
    10801 tgcttttatt ggaagtaccg gtagcggaaa atctacgttg atccaattga tccctcgctt
    10861 ttatgatgtg agtgaaggaa agatcttgat cgatggagta gacgtgagag attatcggct
    10921 aagcaagttg cgagataaga ttgggtttat tccgcaaaaa gcgctgctat ttactggaac
    10981 gattgcagat aatttgcgat acgggaaaga agatgctacg caagaagaaa tggaacgtgc
    11041 agctgagatt gctcaagctt cagaattcat ttctcgaaaa ccagatggat ttaatgaaca
    11101 tttatcagaa ggtggttcca atttttcagg tggacaaaaa caacgattgg caatagccag
    11161 agccatcata cgccgtccgg aaatctatat ttttgatgac agcttttctg cattagatta
    11221 tcaaacggat gcgaagttac gtgctcgtct gaaaaaagaa acgacagaat ctactgtatt
    11281 gatcgtagca caacgtgtgg gaacgatcat gcatgcagat aagatcatcg tattaaatga
    11341 aggagaagtc gtcggtatgg ggacgcatcg ggagttgttg gaaaaatgcc cgatttatta
    11401 tgatattgcc gcttctcaat tatcaaagga ggaattagca tgaaaaaaac cttttcttcc
    11461 ttaaaacgtt tagctcgata tatcagaccg tatcgtgaga cttttctttt agtgatccta
    11521 tttacagttc tgacagtggc tttcaacgtg gctttgccat atgttacagg acttcctact
    11581 acagaaatca gccgtaatat tgccaatggc gaatcaatca atttttctta tatattcaaa
    11641 tgtctcattt ggatcacagt tgttggaata gggtattgta tttcgcaatt actttctggt
    11701 gttttgatga caaatgtcgt tcaaagtgcc atgcatgatt tgagaagaga catagaagaa
    11761 aaaatcaatc gtcttccggt ttcatatttc gataaaaacc agcaaggaaa tattttgtct
    11821 cgtgtgacga atgatgtaga tgcagtcagc ggtgctttac aacaagcttt tattggtatc
    11881 gtaaatgcga tattgggaat tacgttggct gcagcaatga tgttttatat ccagccgatg
    11941 atggcgctga tctctatgat catgattcca acatcgatct ggatctcaaa acgagtgatc
    12001 aatgcttcgc agaaatattt tcaaagcatg cagaattctc ttggtgagct aaacggctac
    12061 gtccaagaaa atatgacagg ttttagtgta ttgaaagtat atggacgcga aaaagaaaca
    12121 ttggaaggat tcaaaaaagt taatcacagc ttgaaatact ttgggtttcg tgcagcattc
    12181 atttctggct tgatgatgcc tctagttcaa ttaactgcct atgctactta tattggtatg
    12241 gctgttctag gaagctttta tgttattact ggggcgatcg ttgtcggtca actacaagca
    12301 ttcatccaat atatttggca aatcagtcag ccaatgggga acgtgacaca attgtcttca
    12361 gttttgcaaa gtgcatcagc ggcaacgaaa cgtgtattcg agattttaga tgagccagaa
    12421 gaaaaagaaa acaaagtaga tgcttcactg ccagaaacga ttttaggaga tgtgacattc
    12481 gatcatgtcg attttgcata tgatccgaag aaaccattaa tccaagattt gaattttgaa
    12541 gtgaaagctg gtcaaaccgt agctgtggtc ggtccgaccg gtgccggcaa gacgacattg
    12601 atcaatctat tgatgcgttt ttatgacgta gacaaaggag caataaggat tgatggaatc
    12661 gacaccaaat caatgagtcg cagtgatgtg cgttcgctat ttggtatggt cttgcaagat
    12721 gcatggcttt atcaaggaac gattgcagat aatatccgct tcggaaagct tgatgcgaca
    12781 gattatgaag tagttgatgc tgcgaaaaca gcaaacgtag atcattttat ccgaacgatg
    12841 ccagatggat atgatatggc catcaattct gagggagaca atgtgtcttt aggacaaaaa
    12901 cagttgctga cgattgcccg agcagtggtc tccgatccta aaatcttgat tttagatgaa
    12961 gcaacaagtt cagtagacac ccgtttagaa gcgttgattc aaaaagcaat ggatcgcgtg
    13021 atggagggac ggacaagttt cgtcatcgct caccgtttat cgacaatccg tgatgcagat
    13081 ctgattctag tgatggatca aggtcagatc attgaaaaag gaacgcatga gagtttattg
    13141 gcacaaggtg gattttatga aaaactgtat aacagccaat ttgctgagga agcagaataa
    13201 gtcatataag aataaaacag tttaaaactt attttttgtt ctctattctt gataatggta
    13261 aagtaaagtt atcaagaaaa gtgaggacac ggagatggaa cagtttttaa atgaaaaaat
    13321 tactgaagcc aaaagagaag ttgatcgttt aacgcacgtc tgtcagacga agccttttga
    13381 ttcagctgat ttttttgaaa atgagtttca aatcgaacgc ttggcagcac aaatagaagt
    13441 gtacgaatta attttaaaaa aagtaataga agaaaatata gatgtacaat aaaaacaggt
    13501 aaaacgtcag ttaccagata ctgtaaatag acatctggcc tgagcaggtt ttacctgttt
    13561 tttttcttat gaaataaata tatgctatga tacctttatt caataggatt agtttctaca
    13621 aaaaatgaaa ggagaaaaat aaatatggaa cggtttatag catcaaatgc cacagtgatt
    13681 ggtgatgtga cattgtcaga agatgtgacg atctggtatc aagctgtttt acgcggggac
    13741 agtaattgga taaaaatagg acaaagaacg aatatccaag atggtacaat catccatgtc
    13801 gatcatgatg cacctgtaga tattgcggag aatgtgacgg taggacatca gtgcatgcta
    13861 catggctgta caatcgaaaa aggggcgctg atcgggatgg ggaccacgat attgaatcat
    13921 gcggttattg gtgagaatag tttgattggt gctggatcat tagtaacaga aggaaaagtt
    13981 attcctccta atgtcttggc ttttggtcgc ccagctaaag tgatccgtcc tttgacaaaa
    14041 gaagaaatac aaaaaaacaa agaaaacatc cagcattatg tcgagatagg tcggatgcat
    14101 gcgcaaggaa aattcaagga gcaaagatag gcagtagcat ccataaaata aaaaaggatg
    14161 gtcagtttga gttgaccatc cttttttatt tggtttagat aagagagctt aaaaaagctt
    14221 cctttgaaac agattaattt aatgaagaac tgttttccat gacttcatcg atcaatccat
    14281 atgcttttgc ttgttcagct gtcatatagt tgtcacgatc tgtatctttt tcaatcactt
    14341 caagcggttg tccagtgcgt tcagctaaaa ttttgtttaa gcgttcgcgt gtttgcaaaa
    14401 tatggcgtgc cgcaatttcg atttcagttg cttgcccttg agcgccgcca agaggttgat
    14461 ggatcatgat ctcagcattt ggtaaagcaa atcgtttacc ttttgtacca gctgtcagca
    14521 agaagcttcc cattgaagca gccataccca taacaattgt ttggacatct gctttgacaa
    14581 agttcattgt gtcgtaaata gccatacctg ctgtaactga accaccagga gaattgatat
    14641 aaagatagat atctttttca gaatcttgag cgtctaagaa aagcaattgg gcgatgatcg
    14701 aattagcaag atcatctgtt acttggccgc ttaacatgat gatacggtct ttcaataaac
    14761 gtgagtagat atcgtaagct ctttcacctc gtgaagattg ttcaatgact gtaggaatta
    14821 aattcataat agagttcctc cttgatttcg tttagaaata gtgtaccata atttagtttc
    14881 taatacctaa aatgtagtat acatttttgg tcaaaaaagg tcaaataaaa aacttaggca
    14941 aattagtcgc ataaacccgc tttatggtat gataagcaga gaaacaaaac aaggaggaac
    15001 aacagattga tagttggtat tactggcctt atcggagtgc tgacaggtgc tgtagttgtc
    15061 tatatcggca tgatactgca aatgcgtcac ttggaaaata aagaacagcg tagacgtgaa
    15121 ttggaattga aagtcaaaga aatcgagacg ctgaatcaat taaataaaaa gatcaacgag
    15181 atcttgcaaa aacggacaac gctgatggaa gaatatgtca gctttgatgc atttgatgat
    15241 tgttatatca cgattgacga ttttgcgtat ctccaatcat tttcagcgca aaatagtttt
    15301 tatctgccaa attatatttt agacgagcta tttaagaata tctcccatcg aaaagtgatt
    15361 ttatctccag atgaaacaat gaagattggt ggatatgctt ataaaggcgg acgcgtgatt
    15421 ttagagaatt ttacggatag tctgactgaa atgatcaatg aaaaaaaagc tcagttgaag
    15481 actatgacgc gccagccgat tggtttcttc tcgaaagatg atgtttggag ctgatatttt
    15541 gaagcattgc cgttgcacat gagagcgtgg taatgctttc tttttttctt aatgatacaa
    15601 tagaactgaa cggagtgaag aaagatgtta caaatctatg cccatcgcgg aagcagcggc
    15661 acccacccag aaaatacgct tcctgcattt gcagaagctg tacgagtagg tgcagatggt
    15721 atcgaactag atgtccatct aagcaaagat ggttatttga tcgttatgca cgacgaagaa
    15781 gtggaccgga cgactaacgg taaagggctg attcgagaaa aaacattgga agaactcaaa
    15841 aaattgaatg cagggggcaa attcagcaaa gaatttccag cagctaaagt tcctgaattg
    15901 agagaagtgt taggactgct cctccaaaaa aattaccgag ggatgctaat gattgaaatt
    15961 aaaactgatc agtatgaata tcccggtatc gaagaaaaat tagccgaaac attaaaaagt
    16021 agagattggc cttttcaaca tgcatattgc agctttcatt tggattcttt ggaaaaaatc
    16081 gcattactgg aaccggagat acagctggac ttattgatga gtacttctga taaaaagatc
    16141 caactagcag cagaaacccc ttatatagaa ggagtacatc caaaaaatac ttggttgttc
    16201 gaacatccag tccaggcagc tgattttcca aaagcaattc gtgcatggac gattaacgat
    16261 gaagaagaaa tggccaaatg tcaagaactc aaaatagatg gaataataac tgattttccg
    16321 gagaaagctc ttcggtggaa acaatcaacg aaaagtaggt aaaatatgga aaaagtatta
    16381 gtgatcgtcg gtccgacagc agtcggtaaa acagcgctaa gtgtggaact cgcacaacta
    16441 tttggaggag agatcatcag tggtgattca ttgcaaatct ataaaaatct ggatatcggt
    16501 acagcaaaaa tcaaagaaga agagatgaat aatgttccgc atcatttgat tgatgtgatc
    16561 gaacctactc aacgttactc agccgctgat tttcagcatt caggtcgaca attgattacc
    16621 gagattgcga accgagggca cctacctatc atagctggtg gtacgggtct ctatatccaa
    16681 tcccttctat atgattatca gttaggagcg acagaagaag cgaatcctga gattagaaaa
    16741 aagtatgaaa cgttagctga aacaattggt tcccaagcat tatggaatca gttgaaagaa
    16801 aaagacccgg cagctgctga gaaaatccac tggaacaatc aacgcaaagt gataagagct
    16861 ctggaagttt tagagacgac aggacatagt atcacggcac ctaaagaaga gccaaagcaa
    16921 ttgtatgatt acctcatgat tggattagat acgaagcgta gtattcttta tgaacgaatc
    16981 aatcaaagag tcgatttgat gctagcagaa ggtttagtag cagaagcgcg taaggtgtat
    17041 gagcttggag aagtccaggc cagtcaaggt attggatata aagaattttt cccttatttt
    17101 gaagggaaag aaacattgga agaagcaaca gaacaagtca aactacattc gagaagatac
    17161 gcgaaacgtc agttgacgtg gtttcgtaac cgtttggatg cacagtggtt tgatcttata
    17221 agtgagccaa atcaaaaaag tcagattgag caaacaatca aaaaatggct ggaggcggaa
    17281 taaaatggaa gaaaaagtga tcatcgtagg ggtagaaacc gaagcaaacc agcgttactt
    17341 ttcagagtca atggaagagc tagttcagct gacgaatacc gcatcaggag aagtcgtatt
    17401 cacaattaca caaaagagac cacaagtgga tcggcaaacg attatcggta aagggaaatt
    17461 acaagaatta gttcaacaag cggatgcgca tgaagcggat ttgatcatct ttaatcatga
    17521 gctaactccg agacagagcc aactgattac cgatgctgtt ggtcttccgg taattgatcg
    17581 cgtgcagctt atcttagata tttttgcgat gcgtgctcgt tcgaaagaag ggaagctgca
    17641 ggttgaactt gctcagttag aatacctgct gcctcgttta gtagggcaag ggaaaacatt
    17701 atctcgtctt ggcggtggga tcggaacaag agggccaggt gaaacaaagt tagaaacaga
    17761 ccgccgacat atacggaata aaatttttgc tgttaagaaa gaattgaaag aagtagaagc
    17821 tcatcgagag cgcaatcgcc aaaaaagaaa aaatagcgag atttttcaga ttggacttat
    17881 tggctacacg aatgccggga agtcaactat cttgaatcta ttgacacaag cggatactta
    17941 ttcgaaagat caattgtttg caacgttaga tccattgact aagagatggc gttttgctga
    18001 aggatttgag attactgtaa cggataccgt cgggttcatc caagacctgc ctacgcaact
    18061 gatcgatgct ttccattcta cattagaaga aagtcaaaat atggatcttt tgctacatgt
    18121 agtcgatgct agttctccag atcgtatttt acaggagcag actgtcttaa aattgatgga
    18181 tgaactgaat atgaaagaaa tgccgatact gactgtttac aataaggcag accagatcga
    18241 cccagcgatg ttcacgccta cgctattccc aaatgtattg atttctactc agacgaaaga
    18301 aggtaagatg gcgttgatcg aagcaatcaa acgtcagctg atggaactaa tgacccctta
    18361 tacactttct gtgccaagca acgaaggaca gaaattaagc gagttgagaa gacaaacaat
    18421 ggttttggac gaagcgtaca tggaagaaac aaacgaatat gaagttaaag ggtttgcaaa
    18481 aaccaattca aaatggttaa gaaaaaacca ataaaatttt atttttttaa
//
LOCUS       DAIGWC010000060        18444 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.061, whole genome shotgun sequence.
ACCESSION   DAIGWC010000060 DAIGWC010000000
VERSION     DAIGWC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.061"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..1050
                     /locus_tag="NOB74_002065"
     CDS             <1..1050
                     /locus_tag="NOB74_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HCI1221234.1"
                     /translation="FLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMT
                     TGAVVSGAFLGNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILG
                     HNSHSADLASINEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALV
                     LSFIHEKSLTVGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGG
                     LLIKYLIVDTIVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSF
                     DDVGLSKTYLTRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVF
                     TILGGFLLNRRRVKN"
     gene            complement(1331..2350)
                     /locus_tag="NOB74_002066"
     CDS             complement(1331..2350)
                     /locus_tag="NOB74_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1221235.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(2372..3379)
                     /locus_tag="NOB74_002067"
     CDS             complement(2372..3379)
                     /locus_tag="NOB74_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI1221236.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(3372..4037)
                     /gene="pgmB"
                     /locus_tag="NOB74_002068"
     CDS             complement(3372..4037)
                     /gene="pgmB"
                     /locus_tag="NOB74_002068"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCI1221237.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(4030..6324)
                     /locus_tag="NOB74_002069"
     CDS             complement(4030..6324)
                     /locus_tag="NOB74_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCI1221238.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            6584..8749
                     /locus_tag="NOB74_002070"
     CDS             6584..8749
                     /locus_tag="NOB74_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1221239.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            9053..9886
                     /locus_tag="NOB74_002071"
     CDS             9053..9886
                     /locus_tag="NOB74_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCI1221240.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(9988..11688)
                     /locus_tag="NOB74_002072"
     CDS             complement(9988..11688)
                     /locus_tag="NOB74_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221241.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            12195..13355
                     /locus_tag="NOB74_002073"
     CDS             12195..13355
                     /locus_tag="NOB74_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1221242.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            13371..13814
                     /locus_tag="NOB74_002074"
     CDS             13371..13814
                     /locus_tag="NOB74_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1221243.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(14297..14827)
                     /locus_tag="NOB74_002075"
     CDS             complement(14297..14827)
                     /locus_tag="NOB74_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HCI1221244.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            14932..15483
                     /locus_tag="NOB74_002076"
     CDS             14932..15483
                     /locus_tag="NOB74_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI1221245.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(15636..16109)
                     /locus_tag="NOB74_002077"
     CDS             complement(15636..16109)
                     /locus_tag="NOB74_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI1221246.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            16247..17719
                     /locus_tag="NOB74_002078"
     CDS             16247..17719
                     /locus_tag="NOB74_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI1221247.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            17716..18426
                     /locus_tag="NOB74_002079"
     CDS             17716..18426
                     /locus_tag="NOB74_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HCI1221248.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
BASE COUNT         5672 a         3333 c         3809 g         5630 t
ORIGIN      
        1 tttttaccga cagcatttct tgtttgtgca attgtcggag tgactgtcgg cagttcattt
       61 acaacgattt cgacgattgg aattgctttt ttggggatcg gtcatttact tggattcaat
      121 gatgcaatga ctacaggcgc agtcgtttcc ggtgcctttt tagggaataa ctgctcgcct
      181 ttatcagata cgaccaactt ggcagcgggt attggaggag ttaatctatt cgaacatatc
      241 gctggtatgc gttatacgga tttcccagca ttcgtccttt cgttgatttt ttatacgata
      301 ttaggacata acagtcattc agccgatcta gctagtatca atgaaatgat ccaaaacatg
      361 aaagcgagct tttggatctc tccttggaca ttgattccac tagttatttt atttgggggg
      421 gcaatcaaaa aaattccggc tatccctaca ttactagcgg gatcgacagc tgctctcgtt
      481 ctttctttta tccatgagaa aagtttgacg gtcggaaaag cagcagacat cttgatgaat
      541 ggttatgtcg caaatacacc tgatccaaag ctagatgaac tgctttctcg aggcgggatc
      601 atgagtatgt taggttctgc tagtttgatt ttacttgcat tggcattagg tgggttactg
      661 atcaaatatc tgatcgttga taccatcgtt caagaattaa aagaaaagat ggaccgacct
      721 tctcgtttag tcgggtttac tgccttgagc tgtatcggaa tcaatctgat cgttggagaa
      781 cagtatctgt ccatcattct tccaggagaa acattcaagc gttcttttga tgacgttggc
      841 ttatcaaaaa cctatttgac acgaacacta gcggattcag gtgcgaccgt caattctctc
      901 gtaccgtggg gagtcagcgg cacattcatt atgggaacga tgaaagttag cgcgttgcat
      961 tacttgccat tcgccttttt ctcgattctt gcacctgtct ttacaatatt aggcggtttt
     1021 ttattgaatc gtcgacgtgt aaaaaattga aggaaggaaa aaagaggctg ggacagaagc
     1081 gtttaactcc aagaaataag aagaaactca agaaaattgc tttttaaatt tttgtgaatt
     1141 tcagcttatt tccgaaggag ttgcttctgc ttccgccgtt tatacgtgtt tagagcgtga
     1201 gacaaaagtg ttctttactt ttgtcccacg ctctttttta cagataaaca atgtgttaga
     1261 agtagtatct tcttttacat aaaaagctga ccataggata aatggtcagc gtatttagtg
     1321 agtcagctat ttagtatggg ttttctaaag gaacgactgt ctctcttttg atcaagcgat
     1381 gagggatgac caaacgtacg ccactgctca attcttcatg gatcaattcg cgcagctttt
     1441 gcatagcgac acgtcctaat tcggagatat cgatatcgat acttgtaagg taagggtgtg
     1501 ttaatgttga gaagatcgag ttgttgaagc taatgacgga gagtgtctct ggaatgacat
     1561 agccatacat ttgcgccaac tgcatcgtgc gaagggcgaa gatatcgtca atgaccacca
     1621 atgctgtggc ttcgttttct ttcaacgttt tctcaaagga cagataatcc tccggatgct
     1681 ctagtactac actggataac gcaggaagac cagccatcat cattgctttt tgataaccga
     1741 aatatcgttc gaaatacaaa ctttcatgag tcgtgtttgt cacaaacagg atattcttat
     1801 gtccattctg gatcaaaaat tctgttgctt gtttacctag aagctggtta tcattatcta
     1861 cataaacgat ttcgttctca tgatgataag gctgtccgat caaagtgaaa gggatgtggt
     1921 tttggtataa ataatcaatg acagtatctt gactatctga atacactaga ataaaaccat
     1981 ctacttgttt ttgtaaatgc atacgctgga cgttctctaa cagcaattca aaatttttag
     2041 cagtagcgat tgctgtagtc atatcataat tccgcgcttc ttcgttgatt gcttccatga
     2101 tctcaagata aaatgggtta ccgatccgct cttttgaatc aagagggggt aagattacgc
     2161 cgatggcact ggaaatgcgt tttcctagat tgcgggcagt catgttagga acataaccta
     2221 gttcatccat aatttttcgg actttcttct ttgttgtctc ggaaatacta ggatgatcgt
     2281 tgatgacacg agagacggtc gaggtggcaa caccggcttt tttcgccaca tcttttacgg
     2341 taatagccat gataaaaaca cctttctctt gttattgtgc agagaaccga taaatcgtct
     2401 gactgatccg ttcttgacca ggatggaggt tgatcgatcc aaatttgggg aaatgaacga
     2461 tatcagggat ttcttgcggt tcgattgcta atccgtagtt tgaatgcatc tgttttccat
     2521 tgacagagaa atcagcttcg aatccagtcg tagaaaataa taccatactt ttattagaag
     2581 ttgctatagt catttggcga ccagaatgct tctcgaataa ttgtaaggaa gttttggaaa
     2641 gcctaggatg atgcaaaaga aatacatcat ctagtccatc tggataacat gcaaggatct
     2701 cttgcagtgt tggggatttt ctaaagtcga ttggcagttt ttcttttttt gtccaatttc
     2761 cagtaggcag tttttcttga tctaattcaa gcacaccatc taaaaagacc gttaactgat
     2821 gttcatagat gtctcttgtt ccatttcctg aaaggttgaa gtaggcatgg ttggtcggat
     2881 tgcagatggt ttcaacaagg ctactagcag aggttgtcat ctctaattcg ttttttgtta
     2941 aacggtaagt gatcgtagca gtgattggtc ctggataggt agaaaattca tcttttaagt
     3001 aaaagaccac acctattgat gatggagttt tgaaaacttc tacttcccaa aattggaaag
     3061 accagccttt cgtgccaccg tggatatggt gtgatccgca gtttttctcc aatctatgct
     3121 caccccaaga agcatcccgg atccttccgg ctacaggtcc gacagttgct ccaaaaaagc
     3181 ttttgtctgt tagaacatct tcgaaacgat cgtaagacaa taaaacattt tctgattttc
     3241 cttctttgtc tggtgcgaag atttggtgca ggcgggcacc gtaattgaga agaacgactt
     3301 ctaagtagtc gttcttcaat gtgattttct ttatttcagt ctctggaact ggtacgacgg
     3361 agatctctgg attatccatg gtcatgccac ttttctttca agtaatcgat cgtaagaaaa
     3421 gtcgtatcag ggacaagcgg gatctcctct ccaaggtctt cagcacgtcc cacgccaatt
     3481 ggttgagcgc cacttgagag gatggcttgg ataccggctt gcgcgtcttc gatcccgata
     3541 cattcttctg cttttagtcc gacagctttt gctgcaagga ggaagatatc tggcgcaggt
     3601 tttccgtttg ttgcttctgc cgggtcggca atagcatcaa agtaaggtgt aagacccatt
     3661 ttttcaagta ggaatggccc gtttttactt gcagaagcaa gagcaatctt gattttttct
     3721 tcttttaaag aatccagtaa aggcacgacc ccggggaaga catcttttgg ttcgatcgtc
     3781 tggatcatct ctaaataata atcgtttttt cttttcgcta attctgcaaa ttcttccttt
     3841 gaaaaagagt gttcttttcc gccataagct aaaagcaaag agagtgagtc ttctcggctg
     3901 acgcctttta gctgttcgtt gaatgtgtgg tcgatcgtaa tgccgatttc ctgaccaagc
     3961 tttcgccaag cacgataatg gaattcagca gtatcggtaa tgacaccgtc taaatcaaac
     4021 aatacccctt taaacatttg cttcctcctt tcttagcgtt atttctagac gatccgctaa
     4081 agaataagac tgttcataga cgtaaatttc tagaggagaa ccttctaata actcgaaagt
     4141 aacttgttca tctgtgactg agatgaacaa taaacgtccg cgataattga tatggaaaga
     4201 ataagctttc caagtttttg gcagaaatgg tgcgaatctc aactgatcat gggcagtttt
     4261 catttgagca aatccttgga caatcgacaa ccagctacca gtcatggaag tgatgtgcaa
     4321 gccgtcttct gtgtcgttat tgtaattatc caaatccaag cgagctgttc gctggtacat
     4381 ttctacagct ttgctttcca ttcctaattc tgctgctaaa atcgaatgga tacttggcga
     4441 aagggaagac tcatggacag tcattggttc atagaaatca aagttttttt gcttttcttc
     4501 ttttgtaaaa gtatcattga agaaataaat cccctgtagt acatctgcct gcttgatgaa
     4561 gcaagatcta aggattttgt cccaagacca atgctgattc agaggaagat cgcttgtggg
     4621 aatatcggat acaggcatga gatctttatc taagaatgtg tcatgctgga caaagattcc
     4681 taattcttcg tcaactggga agtacatgtt ctctgcgata tctttccatt tggctagttc
     4741 ttcttcgctg atagtgatag cagcttcttt ttgataagtt aaataatttt ctcgcgtgta
     4801 acgcaagacc caagctgcga tcgtatttgt ataccaattg ttattgatat tgttctcata
     4861 ttcgtttggg ccggtcacac cgtggatcat gtatttattt gctcgttttg aaaaatggac
     4921 acggtctgcc cagaagcgtg cgatttctgc taaaacttcc agtccttcat ttttcaaata
     4981 ttccgtatcg ccggtgtaat tcgtataatt gtagattgca taggcaatcg cgccatttcg
     5041 gtgaatctcc tcgaatgtga tttcccactc gttatggcat tcgacaccag tgaaggtgac
     5101 cataggataa agcgcgcctt ttaatccttg ttgctgagcg ttgtggattg cttgcggcag
     5161 ttgattatgc cgatatttca gcagattctt agttacttca ggtttggcta aagcaagata
     5221 aagagggaca gcatacgctt ctgtatccca gtaagtggct ccgccgtatt tttctcctgt
     5281 gaatcctttg gggccgatat tcaatcgttc atcttcgccg tagtaagtag agaatagttg
     5341 gaacaaattg aatcgaatac cttgttgtgc ttcttcgtct ccttcgatga ccacatcggc
     5401 aagcttccat cgttctgccc aagccgctgt ttgctcttct tttgcttgga tataattgtt
     5461 tgtctggttc gttaattctg agacagcttt ttctgcttgc tgcgcttctg gaatatctct
     5521 actagtaaga acgataattt ctttttccac tgaccatgtc tcaccttgag ataattctgc
     5581 agacaagcaa ccatgtaatg ctaaagtatc ttcgtgatag tcagggatga ctgattttcc
     5641 attaacgaaa tggcgcattg ctgcagtaac agtaaattgt tcaatcccaa agttgtttgg
     5701 aatagtttta gtcgtcaaat agccgatttc ttctatagtt ccacgatcaa tctcattcca
     5761 aaaatgttca tcatagttgc tgtcttcgtt ttgaacattt ccatccaatt ttgatacgag
     5821 tttgactgtt ccgctacctt caagcatttc tatagttaaa tagatataag ctgattcttt
     5881 tttgacaatg ctcagaaaac gttcgaagga aatgcgtact ttattagtag aagtagtgat
     5941 tgtgaatgta cgagataata caccattttt catatctaat tcccagtaaa agtcttctgg
     6001 ttccaaagaa gccaagtcga tcagctgatc gttgatcgaa atatctatcg cgataaagtt
     6061 caaggcgttg atcacttttc caaagtattc tggataacca tttttccacc agccgacacg
     6121 tgtcttatcg ggataccaga cacccgccaa ataagtacct tgatggtggt cccctgagta
     6181 agtttcttca aagttcccgc gcatccccat ataaccgttt ccaatacttg ttaaagattc
     6241 ttgcagtcga agattttttt tatctaattg tgtcgtgctg attttccatg gatcaatagc
     6301 aaatagtcgt ttgatctgtt tcatttttct cctcctaatg agctgtttta tacgttcata
     6361 ataaacgcaa ccgattgcac aagtcaatag acaaaagaaa atatttcata gaaaaaagct
     6421 taaaaaaata aatttttagg agaaaattat agaagggaac acacgtatta taggttttat
     6481 agaatggtat agacagaaaa ataaaaaata aagcatttac aaaaaagaaa acgcacgcta
     6541 taatacgttt aacgaaaccg attgcgtaaa ggagctaaac ggaatgaaaa agatatttag
     6601 ttttgagttt tggcaaaaat ttggaaaggc tttaatggtt gtggtagcag ttatgccggc
     6661 agctgggttg atgatcagta tagggaaatc aattcccttg atcaatcctg attggacgcc
     6721 gcttgtcaca acgggcggag taattgaaaa tattggttgg gcaattattg gtaatcttca
     6781 tattttattt gctttagcaa taggaggaag ttgggcaaaa gaaagagcag gcggagcatt
     6841 tgcagctggg atctcattta ttttaatcaa tcggatcact ggggctatct ttggtgtcac
     6901 aagtgacatg cttgcgaatg aagatgcatt tacccacact ctgttcggta cgaagatcat
     6961 ggttaaagga ttttttacaa gtgtattgga agcaccagct ttgaatatgg gagtattcgt
     7021 agggatcatc gctggatttg tcggggcaat ggcttataat aagtactata attatagaaa
     7081 attgccggat gctttgtcat ttttcaatgg aaagcgcttt gttccgtttg ttgttatctt
     7141 atggtcaaca atcgtggcat tgattcttgc tgtggtgtgg ccaaacgtac aggctggaat
     7201 caataatttt ggtttatgga ttgcagaatc acaagaaagc gcaccgattc tagcaccgtt
     7261 tttatttgga acattagaac gtttactatt gccatttgga ttgcatcata tgctgacgat
     7321 tcctatcaac tatacacagc ttggcggatc gtatgagatt ttatcaggcg cacaggcggg
     7381 gacacaagta tttgggcaag atccgttatg gttggcttgg gccactgatt tagtgaatct
     7441 taaaggtgca ggggatatgt cgcaatatga gtttgtgttg cataactgga cgccggctcg
     7501 tttcaaagta ggacaaatga ttggttcttc aggtatcttg atgggaatgg cttttgcgat
     7561 gtatcgtaat gtcgatcctg ataagaaagc aagatataaa tcaatgtatt tttcagcagc
     7621 gttggctgtc tttctaacag gtgtaacaga accattggag ttcatgttta tgtttgctgc
     7681 tgtgccatta tatgtcattt attcagtgat ccaaggggct gcatttgcga tggcagatat
     7741 cttgccattg cgggtccatt catttgggaa tatcgaattg ctgactcgga caccgttagc
     7801 tatcaaagcg ggtctaggtg gagatcttat caacttcgtg ttgtgtgtga tcgcttttgg
     7861 tgttgttacg tatttcttag caaatttctt gatcaaaaaa ttcaactttg ctacaccggg
     7921 acgtaacgga aattacgaca atgacagtga agaaaccgtt gtatctaaca gcggaacagg
     7981 aacagcagat cagcaagtgg tccagatcat tcatttgctg ggaggaaaag aaaatatcaa
     8041 agatgtcgat gcttgtatga ctcggttacg cgtaagtgta aatgatcgag aaaaagtagg
     8101 gactgaagaa gcctggaaac gagcaggggc gatgggattg atcgtcaaag acaatggagt
     8161 ccaagcagtt tatggaccaa aagcagatgt cttgaaatca gatatcgaag atctgctgca
     8221 atcaggagca gagattccag agccagaaat ggtttctaca ggaaatggac aagcaggtag
     8281 taagcaatac ttaggtatag aacaagaact agtttccgca gcttctggag aagtgattcc
     8341 tttatctgaa gtaaaagatc cggtattctc acaaaaaatg atgggtgacg gctttgctgt
     8401 tattccaaca tcaagagaag ttgttgcgcc gatcgctgga aaagtgacaa gtattttccc
     8461 tagcaaacat gcaattgggc tggaaacgaa agatggtatc gaagttttga tccatatggg
     8521 aatcgataca gtccaaatga atcagccagc ttttgagatt gctgtcaaag aaggccaaga
     8581 agtaggaaca ggaacgaaat tagctgagat ggatcttgat gtgatccaaa acgaagaaaa
     8641 agatccaacg atcatgatcg tatttacaaa cgataaagta gaagaagtag tgatcaagca
     8701 attaggtaca gtgacagctg gtaaagtgat cggctccatt aaaatgtaag gagaggttgt
     8761 gaaaaagctg tcctgcatca agtcataaga acagccaaac aaaaatagct cctcctattt
     8821 ttcgtttggt tgggcttatt accgagaagc agcagtttga atactgttta gtggagaggt
     8881 cgtgaaaaag ctgccctgca ccaagtgata aaaacagcca aacaaaaaat agctcctggt
     8941 ccattgagct tattactgag gagttagcag gagaacacta tttgctggag aggttgtgac
     9001 aaaaattttg tcacaaccct tttgtttcga aatgaagaca aggagaaaac caatgaaatt
     9061 catgacactc aacacgcata gctggcttga gccagaacca gagaaaaaat tgcaagaatt
     9121 agcagataag atcctgttag aagattatga agtgattgct ttacaagaaa tcaaccaatt
     9181 actggaatct gaagaagtag aacctgcgaa gctaatgaag ttctgtccgg taaagaatca
     9241 agtacctatc cgtaaagata attttgccta ccgtttagtt cagcttttaa aggaacacgg
     9301 aaaagagtat ttttggagtt gggaaatgag ccacatcggt tatgataaat atgaagaagg
     9361 aaatgcactg cttacgaaaa aaacattgga aagtcaggtc cttaccgtct cccaatttca
     9421 aaagaaagaa gattatcaga cacgcaagat cttgattggg aaaacaaaga tagatgatca
     9481 ggacattttt gtctcgagct gccacttttc ttggtggaca gataaaaaaa gtggctttta
     9541 ttttgagtgg aaaaacttgg aaaactactt tttggaaact cgcgtaccac tttttttcct
     9601 aggtgatttc aataatccag tagactctca aggttattat actgtaagag aaagttgcct
     9661 tcttcttcaa gattcgtatg ttgtcgcgaa tgaaaaagga aaagcagcta ctgtggaaaa
     9721 gaaaatagat ggttgggaac aaaatacaga aaaattgcgt atagatttta ttttcgtccc
     9781 tgaaggaatg caggttaaaa aatatcaacg gatttttgat gggatcgata gtccaatcat
     9841 cagtgatcac tacggggtgg aaatcgaatt agatgtgaac gaataaaaaa tataacatat
     9901 aacataaaaa aactgattaa aataaaactc tccaaacgat tataccgttt ggagagtttt
     9961 ttgatcggat gtatttatcc cttttgccta agcacgtaaa agcttgtatc tatgataaat
    10021 aaataaacat agcaaggtaa accagccaat caaagtaaga gaaagaatga aatagaaata
    10081 gattggcgtt tgataatgaa gcgtgagctc gttgattcct ttttgctgct tcacgattgg
    10141 ggtcccgata tctgttactt cataatcagt caatgttttt ccattttgct gtagcacagt
    10201 ccgatcgtag acgataacag ggatatgaac agttttgtcc ccagtgtttt tccacttgat
    10261 tgtcaaaaga ccgcctggat gtgtttttat aaaagttgtt tcgttttcta gtatttcttc
    10321 gttataccgg tcgtatttat tgtcttttgt ctccttatag attggcagat agtcaggtgt
    10381 ggttttttgg aaaacgaaca agctggtaga catatctttg ctgaagaatg ttttccttgc
    10441 ttcttccggc gtatcgaata gataagtatg tcgactgaca aatgtttcat tttcccactt
    10501 ttccagatgc tggtataagt tctggatcgt ctgtgctgaa aaaataagaa tgccaaatat
    10561 acttaaaaga cggaaccact tttgttcaga ccactggttc agtgaaaggg caaggtaaag
    10621 tagaagcaat agcgtaaatg gcacgaaaaa tcgaaatgga aactggatca aactaataaa
    10681 aggcacattt ttttcgatca atgtcgtcca tggaatcaag ctagtagaaa gaaaaaagaa
    10741 aacaagactt gtgtacaaca cgattttttg gaataaggtg ttcttttgtt gaaagaaaat
    10801 aaaaagcaaa aaacctgata atatcaatat aggaaaggcc ttagggtaat ggagccaata
    10861 actgccatcc agatctatcg ccttttgact catttctctg ttaacaaagg gaggaagaat
    10921 cttattccca ctgtaaacaa tagctaatcc tgcccaaata tttgctgtca gaacaaaata
    10981 aagcaagacc gacttaatca gttgaagcag tgcttttcct ttttcagtct ggttaaaaaa
    11041 gtaataaaga taaaaaggga tatacatcaa agctaacatg atcgaagaca gtaaatggat
    11101 ctgtgtcata agtcccactg agacagcgac tttgataaca gggaactttt tatgaaggac
    11161 gaaatcagca atagggatca tacataaagg ataaaaacaa gtcccccagc tagtgaatcc
    11221 ttggttgata gaccagtatt gaatagaata cgtactcatg aataaaacgg ctactggtac
    11281 acttacccaa tttcgaacat tgacatatct cagtaaaatc agcatagaaa atcctgaaat
    11341 aagataaaga atgaaatttg aaagaatctg ataatgaaac cagctacctg caagcaacac
    11401 gatcaatcct tgtaaataag cgaaaaatgg gccgtaaacg gcattcacga tcctgccact
    11461 ttgctggaat ccataaaggg aaggaaaata atggaaatcc ccatatttaa tttgttgcgc
    11521 ggcatcatag aaccgattgt aatggaatgg ggcatcagca cccaaaatta gtttatgtgt
    11581 gaataaatga ggcatgagaa atgccaaagc aatgaaaaaa attgctaaaa atgggccata
    11641 ttttttcaat tgtcgaactc ctttgcaaac tttagataaa ttcatcatat atcctatgcg
    11701 agaggtaggc aagaaattag aaaattcatg aaaatattta tgaattttac aagaaaaaca
    11761 taagtgaaag ttctaaggag agaggatgcg acataagttt tgttgcatct ccttgttttg
    11821 aaacagaatt tttcttaata ctcgaaacaa agtagctttt tcatgacctc tcggtaaacg
    11881 gtgttcaatc agctgcttct cggtaataag ctcactagcc tagaaaatat gagaagctat
    11941 tttctgacta gcgctcttat tactcaaagc ataacgcagt tttcacaacc tcttccttaa
    12001 acggtgttca aaagcttgca tctgcggtaa taagcccaac ccaacaaaaa atatgagtag
    12061 ctattttttt gggctgtact tattacttga tgcaggacag ctttttcaca acctcatcgg
    12121 ctttcatttt ctattttttt cctgaaccca tataataaaa gaaagaacaa aaaaacttgc
    12181 aagggaggac acatgtgaag cagagtaagc aaaaacagtc tcgtcgactt ttgtttcgtt
    12241 tgtttttatt aatatgtatc gtcgtagggt tactgatcgc tttatatcca ttttatgtgg
    12301 attctttaaa tagttttatt gatcaaaaac gtatcgaaca agtacaaaaa cggaccgcag
    12361 ctgaaattga agtgcagcga aagaaaatgg aggagaaaaa ccaacgatta actgaccaag
    12421 gattcaatcc tggtactgat cctttcaatg aaaagaacag aaatgaaagt acaacatcca
    12481 gccaattaga ggaatggctg atcggaagta tcaatatacc taagatccaa ttaaatattt
    12541 cactttatga tcggctcaat ggtaggatcc ttgaaaatgg agcaggcgtc ttgcaaggaa
    12601 cctctttccc gcttggtgga aattcgacgc attcagtgat ctctgctcac agcggtttac
    12661 ctaatcgacg gttatttacc gaattagatc gtttagaaaa cggagacacg tttattttga
    12721 ctgttttggg ggagaaattg gcttatcaag ttaaaaatat acaagtggta ctgccagatg
    12781 acacgtctgt tctaacgatt tcagaaggag aagacttagt taccttgctt acatgtacgc
    12841 cgtatatgat caacacgcat cgtttgctag tgacaggaca tcggattcct tataacgaat
    12901 cggtaaaaaa agaagaagga aaaggaaatc aggaaagaac catgcggcaa tggtttattc
    12961 ttgcaggaac gataatagct gtagtcatac tgttagtgtt tatcggacga ctaatctatc
    13021 agtatagatt aagtaaaaaa gtgcttgatt tttcatttat tattagtgat tcgtcaggga
    13081 aaccggtaaa tggtagttca ttcattttga aacataagaa aaaaacactt actagaaatg
    13141 gtgtgccgtt ttcagtacaa agcgaccatc atgggaaagt caagctggat caattgcctg
    13201 gtggaactta tcgaatcgtt tcagctgatg atcctaaagt tgctgtttct tttggtatta
    13261 gaaaagtaaa acaagagaag atatactttt ttgaggggcg aaaacttgta aaagagcttc
    13321 aaaaaaatgg tttttatttt aaaatcaatg aataagtaag gagagaaaaa atgatccgca
    13381 caacaacaaa attgtctgcc aaagaactgg aatctgttct atcgatttgg ctgcatgcta
    13441 acttggattc tcatgaattc attccatcaa cttattggga gaatcaagta gaatctgtta
    13501 ggaaagcttt accagatgca gtgatttact tagcagaaat agatcaagaa attattggtt
    13561 ttgctggggt gattgatcag tttatcgcag gaatctttgt gaaaagggaa taccggcaac
    13621 aaagaatcgg tacgcaacta atgaaaaaaa taaaagaaac caataaaaca ctgactttga
    13681 cagtctatca aaaaaatcaa tcagctattc atttctatct ttcacaaggt tttacaattc
    13741 aaacacagca aaaagatgaa gcagtaaatg aggaggaact tgtgatgaaa tggaatcaaa
    13801 acgctgattt ttgatgaaca gaataacgaa ataatgctcc cagcctaatt ttttgctggg
    13861 agcattattt cattttgaag tcactaattt aactgtgtga atatgcagtt gttacaatct
    13921 ttgataaacg gtgttcaatc agctgaccct cggtattagc tcaaaaaacg gcaaaatatg
    13981 aggaactatt tttccatttg tttctctaat actcaggtca aaacgctgat ttcacaacct
    14041 cttgataaac ggtgttcaaa cggctgcttc tcggtaataa gcccactagc ctagaaaata
    14101 tgaaaagcta ttttctaact agcgttctta ttactcaaag cataacgctg atttcacaac
    14161 ctcttgataa acggtgttca atcagctgac cctcggtatt agctcaaaaa acggcaaaac
    14221 atgaggaact atttttccgt ttctttctct aatactcagg tcagaacgct gatttcacaa
    14281 cctctctttc acaaccttat tttactcgtt tataattttc atcgaagtat tttccgctac
    14341 ggatatcatc tggcattcca tcgtatggtt cttcgctaat aacatcttca ttgtctatac
    14401 ctgcatcacc catataagtg atcgtagcaa attcaggaac aagtaatttt ggataagttt
    14461 catatttttc acgagctgct tccatttctg cgatatgttc gttttggaaa gtaacagtga
    14521 tttctggatg ttcttcaacc catttaggga aaaagatcat tccgtgaagt ttcttttcat
    14581 ttggcataaa gtccaatgcc acgtctgtcc ctgttggctc tgtccaagtg attttgaata
    14641 cgccgtccgt caatttaacg atatcagctt cttggtcttt tacccaacgg cctttgacca
    14701 ttccgccatg gatacggtaa tcaacagtat ggtcattttt ggcataccat tcatattccc
    14761 aaccattgtc atacgtatag ataaagtgag ttccaataaa atcttccaat tctttaaatt
    14821 ctttcatgtt taagcatctc cttataaatt aaaacatgta ataaactaca tgttttcgat
    14881 tactcattta tgatagaatg gatttaaaga tttgtcaagg agggaaaact gatggcaaga
    14941 aaaaatacac ttcgatatat tttgttaggg ttattaagta agaagaagat gacaggatat
    15001 gaattgaatc aatcgttcaa aaatgaaata ggagaatttt ggcaagcaaa acatagtcag
    15061 atttatcctg aacttgcaaa aatggaagag caaggaatca ttcagcatca agtagagatc
    15121 acaggtgaaa aattggaaaa gaaagtttat gaattaacag aagaagggaa ggaacaattg
    15181 gcagagtgga ttcatacacc caccaatgaa ctaccggtta atcgagacga atttgttctg
    15241 aaattgtatt tcgtcaaaga cgtgaatgat ccggcattag tagaaattat tcagcagcag
    15301 cgtgaccttc atgaagaaaa acgacttcat ctattagagc gaaaaaaaac gatctttcct
    15361 actgaaaaag aaaaacatga aaattacgga cactacctga ttttagcgca tgcgatcaat
    15421 cgggaaacag aatatgcaaa ttggctaaca gatgtattag aagaaagtaa ccgaaaaaaa
    15481 taaaaaaata tccgaacagt gatggagaat tcctttctat atgaaagaaa cgcagatcac
    15541 cgttcggata ttcttatgtt caaacaggcc ttttttcaag tatttatgta gcatctactt
    15601 attaaaaagc ttggtactta ggagattagt ggcgtttaga gttcttttaa caactgttcg
    15661 tagtcagctt tttcatcgac aggaaggagc ttgtaagtta attcgtctgt ctcgttgtca
    15721 tgaatgatgt acatcttagc attctcttct ttgaagttac cgatttgtaa aatcgtatag
    15781 cgttcgtcga tcaattcgat atctttgatt gcttttgaaa aaactttacg gacatggtgc
    15841 attttctttt ggcggatttc tgccttttct gcagcttttg acaaagtaaa tccgtcatct
    15901 aaatattttt tgatcagttc tacttttatg actgtaggta aacgatattt tctaggacaa
    15961 ttcgcatcag cttcgatcga acgaatgaat cccttttgtt cccaatacct taattgacgt
    16021 ggagacacac ctacgatatc acttaattca ctgatgccaa caaccaattg atcattttcc
    16081 aacaaacgtt taagggaagc cccaaccatt tttgtcactc cttttgtcct cttgcttccc
    16141 ttaattatat ccgtattaac ttatgtgtca agtaggttga caaatagcga atttaggact
    16201 aaagtattct agtagtttca gaaaaaattc agaaagaagg agaaatatga gtaacaacca
    16261 acccgtagat atttacggaa aaccatataa tcggacactt ttagttgttg tcttattaat
    16321 tggtacattt tgtaccgttt tgaatcagac cttattgacg acagcttttc ctacattgat
    16381 gaaagctttc gatatttcag cgtctgatgt gcaatggtta acgactggtt tcttgctagt
    16441 caacgggatc atgatcccaa taacagcatg gctgatcaat aaattcagtt caagaaattt
    16501 atatctttct gccatgacga tctttttgat cggaacgatt acttgcttta cagcacctaa
    16561 ttttagtaca ttactaatcg gtcgtttgat ccaagcttgc ggtgtgggag tatcgatgcc
    16621 attattgcaa aatatcatgc tatctatttt cccgccagaa aaaagaggat cagcaatggg
    16681 gatgtcaggg atcgttattg gacttgctcc tgctttaggc cctacattat ctggttatat
    16741 cattgataac taccattggc gtgacttgtt tggtatggta ctgccaatcg ttgttcttgt
    16801 cttggtttta gcattcttcc taatgaaaag tgttattcca ttgtcaaatc ctagcattga
    16861 tattttatcc gctattttat caacgattgg attcggtagt ttactttacg gattttctag
    16921 tgtaggagat gacggctggg gaagcttgaa agtaattggt ttcttagttg ttggtgtgat
    16981 tttcatcgcc ttgttctcat ggcgtcaatt acatttggaa catccattct tggaacttcg
    17041 tgtattcaaa tcatctacat tcacgattgc agctgtttta gctggtgtaa caaatatggc
    17101 gatggtaggg gcagaaatgg tcgtaccatt gtatattcaa aatattcgtg gagaatcagc
    17161 attccattct ggcttgatgt tgttgccggg tgcattgatc atgggggcta tgatgcctgt
    17221 gacgggtgcg attttcgata aatacggcgc gaaacgttta gccatcacag ggatgttcat
    17281 tttgacagcg gcaactgcac catttgcttt cttgacaaaa acgactccag ttttatatat
    17341 cgtgatcctt tatgcgatcc gtatgtttgg gatctccatg gtcatgatgc cggtaacgac
    17401 ttctggtatg aatgcattgc caaataactt gatcagtcat gggacagcgg taaataatac
    17461 attccgtcaa atcgcaagct cgattggtac agctattttg atcagtgtgt tgacgaatgt
    17521 gacaaaagca aatatcccaa gcaaatctgt attggataat acgccattag cttataaaga
    17581 tcaggcaatc aatgccacac tgtcaggtta ccatgccgcg tttatcgtag cgatcatctt
    17641 tgggattctt ggctttatta ttgccttttt attgaagaaa aaagaacctg ttctaatgaa
    17701 agcgggggat aatgcatgat tattggagtt ttgattgtca gcttgcttgc ttttgcttta
    17761 acgaacgtgt tcgctaaaaa aacatggcaa acctttttat ctttgatttt cggactaatc
    17821 ttcgtcgctt cactaagttt gatcgtcgct aatttgtcca atcactttgg aatggaaaaa
    17881 gtaacggaaa caaaaacaga aaaaattgtt tccagtgctg attcccaagg agcagatatg
    17941 cttttgtata aagctttagg gaatggaaaa gaaaaagtgt atctttaccg aacaaatgaa
    18001 aaacaagaaa aaccaaaagc aactggtacg gataacgaaa caaataaagt agaaaagaca
    18061 gacggcgatg ctgaaaaagt gacgaaaact acttattggg aatacaaaaa cgacatgtat
    18121 aaattctggt tcaatattgc tgataacaat cacgaatatg acagccgagt gaatacattc
    18181 aaaatcccag agacatgggt agaattaagt acggaccaag cagccaagtt agctgaatta
    18241 gtgaagaaac agcaaagtac gatggaaagt gaagcaaaag cttatgttca agacggtatg
    18301 gtaaaagcaa tgactgaaaa tccaaaaatg agcaaagcag agcaagaaca acgtacgaaa
    18361 gccttagctg ctgaattcca acaacaagca ttcgcaaaat tagtgaaaga agcaaaaggc
    18421 gaataatatt ttgaacacca tgta
//
LOCUS       DAIGWC010000061        17152 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.062, whole genome shotgun sequence.
ACCESSION   DAIGWC010000061 DAIGWC010000000
VERSION     DAIGWC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.062"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(734..1912)
                     /locus_tag="NOB74_002080"
                     /pseudo
     CDS             complement(734..1912)
                     /locus_tag="NOB74_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
     gene            1942..2352
                     /locus_tag="NOB74_002081"
     CDS             1942..2352
                     /locus_tag="NOB74_002081"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221249.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            2433..3053
                     /locus_tag="NOB74_002082"
     CDS             2433..3053
                     /locus_tag="NOB74_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221250.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            3754..4038
                     /locus_tag="NOB74_002083"
     CDS             3754..4038
                     /locus_tag="NOB74_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221251.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            4041..4958
                     /locus_tag="NOB74_002084"
     CDS             4041..4958
                     /locus_tag="NOB74_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1221252.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTGLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            4951..5733
                     /locus_tag="NOB74_002085"
     CDS             4951..5733
                     /locus_tag="NOB74_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1221253.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            5734..6414
                     /locus_tag="NOB74_002086"
     CDS             5734..6414
                     /locus_tag="NOB74_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1221254.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            6407..7303
                     /locus_tag="NOB74_002087"
     CDS             6407..7303
                     /locus_tag="NOB74_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1221255.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            7498..9147
                     /locus_tag="NOB74_002088"
     CDS             7498..9147
                     /locus_tag="NOB74_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCI1221256.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            9741..10676
                     /locus_tag="NOB74_002089"
     CDS             9741..10676
                     /locus_tag="NOB74_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221257.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            10669..11439
                     /locus_tag="NOB74_002090"
     CDS             10669..11439
                     /locus_tag="NOB74_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1221258.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            11855..12838
                     /locus_tag="NOB74_002091"
     CDS             11855..12838
                     /locus_tag="NOB74_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HCI1221259.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            13285..14322
                     /locus_tag="NOB74_002092"
     CDS             13285..14322
                     /locus_tag="NOB74_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI1221260.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(14411..14734)
                     /locus_tag="NOB74_002093"
     CDS             complement(14411..14734)
                     /locus_tag="NOB74_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI1221261.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(14721..15428)
                     /locus_tag="NOB74_002094"
     CDS             complement(14721..15428)
                     /locus_tag="NOB74_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI1221262.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            15514..15855
                     /locus_tag="NOB74_002095"
     CDS             15514..15855
                     /locus_tag="NOB74_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HCI1221263.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(16026..16874)
                     /locus_tag="NOB74_002096"
     CDS             complement(16026..16874)
                     /locus_tag="NOB74_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221264.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         5461 a         2916 c         3575 g         5200 t
ORIGIN      
        1 taatgaaaaa cgagaaggaa gatgacttta aagtagttta gtatgaaggt cgattgataa
       61 aacgatgtgg attaatgcta aataatgagt aatttttcaa taatacaaaa actgtgtaca
      121 gtattagaag tagagaaacg ctagcgtcga aaaaaagata tttttcgtga aaagtaatag
      181 gggctaaaaa gaaagtatac aatttattta tgtttctaag catataaaaa agagcgttga
      241 aaggaatatt tccccttcaa cgcttctttt ttagaagatt ttaatgacca tctcaacttc
      301 attttcaggt ttaggtaatt catggaagct tgtgtttatc gtgcttaatt gatcaactaa
      361 ccatgtttta ctttttgact cgtagacaaa tctaaaatta atatcattgt tctcgtgttg
      421 aagaggtttc tccaaataat ctggtgaata ttcatagtca acgtaacctg ctaatacaaa
      481 agaaagcagt ccattattta gtgtcagatt taacggatgg tcgtaagctt ttattttttt
      541 aatgtcatat tgtacatctt atgaagactt aatgactact tgtagtcaat agatttaaag
      601 tatttatttt ctcatttatg tatcaagaat aaatactgat ataataaaaa ttatatcaat
      661 gttttgatga agtaatttgg agggagcgtc aataattttg tgtaaataac tcgtccttct
      721 gcaaaataat gggttactca gtaaacattg aagctaatgt atccgtcact tgttggaagc
      781 ctttatggct tctatttaag aatttttgat tgtatgtatc aaagatggat actaggaaac
      841 gctctagtga ttcttcattt tgaaactgct cttttctgcg gctgtatttc ttgatttgtt
      901 tcttgaaaga ttcgattaaa ttagttgagt aaatgcttcg gcggatacca ggcggaaact
      961 cataaaaagt caataaatct tgatttttta tcagtgactg cgtcacttta ggataagttt
     1021 tttgctactt ctcaatcata ctccctaaaa aggtatttgc ctcttccttt gagctagctt
     1081 gataaacagc cttaaaatca tcacagattt cttttcgatc tttgacacgt actttatgag
     1141 caatattacg ggaaacgtga acacagcaat gttggtattt agctttagga taaatctggt
     1201 gaatcgtatc tttcatgcct tttaagccat cggtaataaa cagtaagaca tcatgaaccc
     1261 ctctggagta aatgtcctgt aacaactcat tccaaacgta ggtcgattca gtcggagcaa
     1321 tcgcataact tagtacttct ttagtgccgt cttctcgtat accaatggca atatagattg
     1381 cttctttgga gacggtttgc cgttttaaag gaatataagt agcatccatg aaaatagcga
     1441 catacttatc atttagagtt ctaactttaa atgcatttac ttcttcagtc agcactttag
     1501 tcatgttgga catggtttgg ggcgtgtagt gatgcccata cattttctca atcaagtctg
     1561 cgatttccga catggtaata ccttttcgga agaggtgaat gacggtctcc tctaagatat
     1621 cattcgtccg tctataagca ggaacagtct gttgcttgaa ctcgccgttg cggtcgcgcg
     1681 gaatctggag atgaagttcc ccgtactcgg tcttgaccgt acggtcatag gagccgttac
     1741 gagaattccc cgtgttaaaa ccaatgcgat cgtacttttc gtaatcgagg aaagccgtta
     1801 actccgtttt gagaagcgta ttgacagctt tttccaaatg gacacggaat aattcattca
     1861 aatcgccttt gttcgctaga gtctttagaa tttctgtagt aaaatcgttc atatggaagt
     1921 cctcttttct gtgaatgtgt tgtggtaact ctattctaca gaagggactt ccttttttct
     1981 atttacacaa aatattttac actctcgtca aatataaaaa ctagtacgaa attaatttgt
     2041 aaattattta agcttgataa aataagcaat atcgatgatg taaagtccaa gatattaaca
     2101 agaaaagtaa gcgaaccagt aaagctaacg gcacaagata aaaaaaatgg aattgttctt
     2161 tatggtgatg atgcaaagta taactataat tgggatacct cctcagaagc tgaggtatta
     2221 agtattccta ctaccgatac ttcaggggaa aaagtcacct ttaaaataaa ttttataacg
     2281 gcaatttcta agttggagta tgggaagcaa aaaaagagag ataacaatga tcaatatcta
     2341 cctaaaaaat aacgaattaa tgatgcatat gttaaagttg tttttttgaa ttaaacaact
     2401 caatttattc agttatatgt tcatcgcagc aagtgaacat taatcgagtt ataaaattaa
     2461 taggagctaa aaatataaat aaagttcgat cagaatttat ttttccagaa gattttttta
     2521 actggttttt ttatcaattc agtgaatgca agcgactctt aggtgagaat tattacttaa
     2581 aaggaatcgg cggatttatg gggaatgtgg ctgatgaaca aaatattata aaaggaatat
     2641 ctgaacaaac atcagagctt acagtaacta aagcatttat aagtaatggt gaaagtttga
     2701 aaaatgtaac tgcgcgaatt agaaaagaaa atgaagtaga cattgttttt ggaattgacc
     2761 atgaatgtaa ttcagtgata tatgtaacac aatcagcaaa tttaattctt tttgagaatg
     2821 gttgcaagga cgattttatg gtggtctatt tgtacgatat actaattcca aaacttcgtt
     2881 ccttatatat gtcttctgaa agtatttttg tgagtgaaca aaagggatct ttctcgaaaa
     2941 aaataggtat tgaagtaatt gaatcgatta tgtgtcataa tcatattacg ctagaagaat
     3001 tagaaatttt gatagggcaa aaaaataata acacgaaaat acaagtttct tagaaatcat
     3061 tttttattga gatatctaga taaatgattt attcttcaat caaccaactc gccaagctga
     3121 ggtaatgttt tgaggtaatg ataacataca actttttata ccctagtaaa actctataaa
     3181 caaagactta ttaatttcgc atgaaataca ttcctgtaaa atgcaataaa atagagtttt
     3241 gtttaaccag gtcttaagaa agcccgtaaa gcttcacagt tctcaaaacg ttaattgcga
     3301 ttatcgttcg agttcacgag ttacgagaat cgtactgggc gaagcaatgc tgagcgcagt
     3361 taccttaatc ctaacttttc tggcactttc cacaatttgg aaagtgcctt ttttgtgttt
     3421 ttagctatgt taataggtag gattcttggt ctataatatc attcgatcta taaacaaacg
     3481 ggaaaaagat aaagtatcat caaacaatat tatttatccg cttctgaggt tgtgacagaa
     3541 gtggtcagct tcaagaaata agaaggaatt tacaaaaatt gcttctcatg tttgataaat
     3601 attgtgactt gtgaccgagg agttggcagg agaacaccgt ttattcggaa gaagggattg
     3661 tgaaaagtct tttgtcataa cctcttattt ggtagctaat tgtaaatccc aaacggcatg
     3721 tattattttt cataagtccg tttttaagga ttaatgtttt cttttgcttt ttatatggtc
     3781 tggcttcagc gagaagttcc aacgcatata caaggacgtc tgatgtcaac gataacaacg
     3841 attaccatgg tggccagtcc acttggatta gcactgtttg gtgcgctctt tgattggcag
     3901 acaactcaac cacgtctgcg agacagtctg atttttcttg aaattcaatt ggaaaattta
     3961 cactttcttt atacatttct ggctgctttc tttatacccg tcaactatac ttcacttatc
     4021 aataagaaag aaggataagt atggattttg gaaatgaaac ggtcttgaaa gcaactggta
     4081 taaccaaaaa atacggtgct gccaaagcat tagataaagt atcgatcgaa atcaaacgtg
     4141 gaatgatcta tggtttgatt ggggagaatg gagcgggtaa gtctaccttt atgagaacta
     4201 ttatgggttt gatctcgatt gatgaaggtt cgatcgaatt atttggaacg acgggtttgc
     4261 aggcagcaag acgacgtatg ggtcaatcga ttgaaacccc tgctctttat ccagaattaa
     4321 ctgcaagaga taacctacgt atccaagcag cgaacggcgg tgtgtcggat agagaaatcg
     4381 aagacctgct gaaaatgatg cgattggaaa atacagggaa aaagaaagca aagaatttct
     4441 ctttaggtat gcgccagcgt ttagctattg caaatgcact gatcacgaat ccagaatttt
     4501 tgattttgga tgaaccgacg aatgggatgg atccagcagg gatggcagaa atgcgagaaa
     4561 tcatccaacg tttggtaaaa gaacggggca tcaccgtctt gctttctagc cacttgctag
     4621 atgaattgtc acagatcgcc actcactacg gtattttgca tgaaggacac ttgatcaaag
     4681 aattatcgaa agaagaattg gcacaagaat ctcgtcaatt tataaaaatt gacacttcgg
     4741 cgacggaaca agcagtaacg gttctcgact ctcttggtta tagggattat tttgtccaat
     4801 ctagccgtgt tatccagctt tttgaaggaa ttgaccaagt agcagccatc aatcaagcat
     4861 tggtagaggc aaaagttcct gtggatggta tccacctagt tgggcaaaaa ctggaagatt
     4921 atttcttaca attaactgga ggcaatccac atgtttaatc tattaactgc tgaaaaaata
     4981 aaagtatgga agagccgtaa aatgtgggtc tcactaggac tgatggtcgt acttccgctt
     5041 ttttattctt ggaacgaatg gtatatgcat acaaaatacg gcaatgaatt aaaccaagca
     5101 acggatacag tcatcaacgg tgcaacaggg attttaatgg tggaaaaaat ggctgcatgg
     5161 attcttctgg ctttcgcagc atttgcgtgc ttttatattg gggaagaatt tcaaaacggt
     5221 acgattcgca atacgttatc tttaggacgg aatcgaatga cttattatgt gtcgaaactt
     5281 ctcgttacgc ttttgatcac aacacttggc gtggttttga ttacggggct agccatgatt
     5341 gcttacacac ttgctttcgg atttggtgaa gttgagggaa tcaaaaacta tggaaattat
     5401 gttctaaaag tatttcctgt attgcttctg ctgatattag cgacattatc tgttccagtg
     5461 gctttgacat tcatcactag aagtaccagt gtcagtttgc ttctttcttt tctttatatc
     5521 atgggaacgg ccttcgttcc cggtgttttc gcaaaaatca aaggcttgga atttctaacg
     5581 gagtggttta cggaaacgtg gctcatgtat acggactttg cgcaacaagc aacttattcg
     5641 caagcaccga aaatgattct ggtcagtcta gtaacaatcg tggtatcatc agctctagga
     5701 atgtttattt tccaaaaatc tgacattaag taggtgttcc tgctggaaac tattttgatt
     5761 atcgaagacg atgaagctgt tcattcttta ctggaggagg ttcttgaaca gagatacaaa
     5821 cttcttgatg cttattcagg tacggaagga aaattattgt taagcacata tcctgtcgat
     5881 ttgatccttc tagatctcat gcttccaggg ctttcaggtg aagcattgtt agcagaaatc
     5941 cgacagacat cgaatgttcc gatcatcgtt ctttcagcaa aaagcgatca aagagataaa
     6001 gtttccttgt tggcagcagg agcggatgac tatgtgacga aaccatttga tatcgaagaa
     6061 ctgttgttac gaatcggcat ccaacttcgt catcagactt ctgtccaagt aaaagatctg
     6121 tcgcaacgca tctattacaa ggaaatctta ctggacaaag agtcgaggga tgtaaatgtg
     6181 aatggtgtgg ctgtccattt gacaggaaga gaattcgatc tgctgaagct ttttttagaa
     6241 catccgaaaa aagtattttc gcgagcaaat ctttatgaaa cagtttggca agaaccatat
     6301 tttgatagtg agaaaacagt gaatatgcat atttccaatc ttcgagggaa actagcaaag
     6361 gcacatgctg tgtatattca tacggtgtgg ggagtggggt ttagatttga ttaagtggct
     6421 gttgcttctc gttgttatct ttatgggaag ttttattttc ttcctgcaaa gggaaatcaa
     6481 gagattaact aagaaaatcg ccactctttc tgaacgacaa gaatatggtg gtcgtctttc
     6541 agtcgaattt cgagaaaaga atctaatgga cctagtagat gcactgaata catgggtgga
     6601 tgaaaatgaa caaaaaggac aagcatttca agaaatggaa gaaaacatca gactatcgat
     6661 cgtcggcctt tctcatgatc tcagaactcc tttgactgct attaacggtt atgtacaatt
     6721 actggaacag gtagaggata cggagaaacg ggagaagtat ttaacgatca tcaaacaatc
     6781 tgttgcaaga ttactcagta tgacggatca gttttatgat cttgctcgaa tagagacgaa
     6841 gcaaaaagaa atggatctcc atacgctttc tttttctaaa gaggtggaag aagtattttt
     6901 ctctttttat gaacaatttt ctgagaaaaa tatcgaggta gcgttcgctg aacactcgat
     6961 aaatacaact gtattagcag atccgctcat gttgctgcga gtgctgcaaa atatcataca
     7021 gaatttattg cgttatgcag atggacaagc aaaggtgaca ttttcaaaag aggattcatt
     7081 cattcgatta acagtggcca atcctatcaa accaggagcg caaacctctg ttgaaaaagt
     7141 cttccagcgt ttttataccg aaaataccag ccgcacaaat acggaatcta gcggaatcgg
     7201 gctttacctg tcaaaaaaat tggtggaagg aatgggagga gagatgaccg ctagattaga
     7261 cgggggcatc ttctccatct ccgtcaagtt gcggagggtt taattggctc taatttacct
     7321 gaagtgaatg acaaaaaatt gtatctcgtt ttaaagacat cttctttttt ggaaggtgtt
     7381 tttattttgg tgtgattgat acgaattagg taacgaagac agttattttt gtaccccctt
     7441 ttcaaatagc gcaacagtgc tatactaaaa ctaacaaatc aaggaacgga gagggatatg
     7501 ggccaaagag aatttatcgt tttaattatt attgcagttg ttattttatt agttgtttta
     7561 gacatttttt cacgtttgaa agtaaaggaa acagttcgta gtaattgggg aaaaattcct
     7621 tatcaaccga gatttgataa agaagaaagt ttgaaggatg cgtggctcac ggagaaaaaa
     7681 ttccgttcat gggatagtga aatcgacgat cttacttggt atgacttgga tatgttcgaa
     7741 gtatttgaag ggatcaacag tacctattct agtgtaggtt cagaagcgtt gtatcagcgt
     7801 ttacgtagct ttgattttgg agaagattat cagttagaaa aactaattgc tttttatcag
     7861 gaaaatcctc aactgagaga aagaatccaa tatcaattcg ctcgtttagg aaaaaaagat
     7921 cataattttg caaaacaata tctagcggat ggaaaaagta aaaagattgg acgcgtaggt
     7981 ttatttattt ttcttggctt gcttccgctg gtgggtgtag gtttgcttct tttagggcaa
     8041 gtactaggaa tctatctagc aatcggtggc ttagtattca atacggtcta ttatctagtg
     8101 aagaaacaaa cactagaaac agagctgaat agcatgagtt atttggtttc aacgatttca
     8161 gccgccaatc agttagcaaa aatgacgaca ccacttcaaa aagagctgaa acagcaaact
     8221 aaaccattaa gagacatccc taaattaggt ttttcatttc gaatgaagag cgggagtgaa
     8281 gcagaattga tttttgaata tgtcaacatc atgttcatgc tgccatttat ctcctatcat
     8341 ttcgttctca ctaaattaga aaagcattca actgaagcca tcaagctgtg ggaattgctg
     8401 ggagaattgg aagttgcagc agccgttttg aattatcgca cctatatgcc gatcacttgc
     8461 cgaccagagt ttactgaggg cggtgtgaca gcgaaagata tctatcatcc attgttaaaa
     8521 gaagcggtag ttaatccagt caactggcag aagaatacat tagtcacggg ttccaatgca
     8581 tcaggaaaat ctacgtatgt caaaagtata gccatcagct gtattctagc acagacgatc
     8641 caaacagcga ttgcagaaca gtttaccctg caacctggac atgtgttgac ttccatggca
     8701 atcgaagatg atttatttga aggcgacagt tattttgttt cagaaatcaa atcgatcaaa
     8761 cgtttgctgg accaagtggc ttccaaagaa cgctgctact gcttcgtaga tgagatttta
     8821 aaaggaacaa atacgatcga acggattgct tcttccgctt cagtcgttcg gtggcttgcg
     8881 gagtatccat ctttagcatt tgtcgccaca catgatatcg aattgacaga gattttaaag
     8941 aattattgtg agaatgtcca ctttgaagaa caagtaacag aaggaaaagg aatcagtttt
     9001 gatttcaaat taaaagaagg accttcaagg acccgaaatg cgattgcctt gctgaaagtt
     9061 ttgaattatc ctaaatccat agttgaacag gcccaaaaag aaagtttgtt gttcgatgaa
     9121 cagcgtcagt ggtatccgtt tgattaactt tatcaaacga agcatgatgc gtgggtccaa
     9181 aaagacgatt atcaaaagaa gtacattgat gccaaaaaag tggcagaatt caatgggaac
     9241 gagtctgctg tccagatgat cttggaagat ttagcaaaag acgatacaaa ataaaccacg
     9301 ctgtcttcct tctagcagct tttatcgaaa aaacttagca tcagcgacga gacgcacgtt
     9361 ccatggcaaa gttctccgta aaacaaacag cgaaaacaga aattgaaaat aactatttcc
     9421 attttattta tttcggttaa aataaaagaa aaaagctttc gataaaagga cggaggaaag
     9481 cttaacatga ataaaaaaga caagaacctc agttataagg atcttctata tgtcatcgta
     9541 gtagttgctg tcggtacttt tatgatttta aaagttccag agttgtttag atagttattc
     9601 tatcgaagat gatcatgaac tagaaaacac atctcctctt tgttagcagg tgtgtttttg
     9661 tgtggaagcc aagttgtttt ttcatctgct gtattccatg atacaattaa gaatcatgtc
     9721 tataaggaga taggaaataa atggcaaatg cgcttgaaat aaataatttg aaaaagatct
     9781 atggaagtgg ggtcgaagca ttgcggggaa tcgatctttc ggtgaaagaa ggagatttct
     9841 atgcgctatt agggccaaat ggagctggga agtctacaac gatcgggatt attacttctt
     9901 tagtcaataa aacatctgga aaagtgaatg tcttcggtta tgatctggac aaggatctag
     9961 ttcgagcaaa gcaacagatt ggattggttc cacaagagtt caattttaac ccttttgaaa
    10021 cggtccagca aatcgtcgtg aatcaagcag gctactacgg tgtctctcgc aaagaagcga
    10081 tgaaacgcag cgaaaaatat ttgaagcagt ccaatctttg ggaaaagaga aatgtccgtg
    10141 cacgtatgct ttccggggga atgaagcgaa gactgatgat tgctagggca ttgatgcatg
    10201 aaccacgttt gctgatcttg gatgaaccaa cagcaggagt tgacatcgag ttgagacgcg
    10261 agatgtggga gtttctacga gaattgaacg aaaatggtac aacgatcatt ttgacgacgc
    10321 attatctaga agaagctgaa atgctttgtc gcaacatcgg aatcatccaa tcgggtgaac
    10381 tgatcgagaa tacaagtatg aaagagcttc tgtcaaaact gcaatttgaa acatttatct
    10441 ttgatttagc gccatatgat accaaacctg tgattgaagg atatgcttgt acatttgaag
    10501 atgagcagac aatcgctgtc gaagttgaac gaaatcaagg ggtgaacgga atcttcgatc
    10561 agcttacaag acaaggaatc aaagttcttt ctatgaggaa taagtcgaat cgtttagaag
    10621 aactgttctt gaaaatcaca gaagaaaata atcatacgga ggagaaaaat gtttaatctt
    10681 tattttactg cattaaaaag tttagctatc aaggaaacga accgctattt gcgtatatgg
    10741 gtccaaacac tggttccgcc agtgatcacg acatccttgt attttgttat tttcggaaaa
    10801 atgatcggtg ggcggatcgg tgacatgggt ggtttttcat atatggaatt catcgttcct
    10861 ggtttgatta tgatgtctgc tatcactagt tcgtatgcca atgtttcttc gtccttcttc
    10921 tctcaaaaat ttcagaaaaa tatcgaagaa atcttggtag cacctgttcc tacgcatgtg
    10981 attatttggg gctttgtgat tggtggtgtg ggtcgcagta ttctcgtcgg ctctctcgta
    11041 acgatcattt ccttgttctt tgtaccactt catgtgtatt catggttcat ggtcatcatt
    11101 acattattga tgacggcaat cttgttttca ttagcaggac tgctcaacgg gatttttgct
    11161 cagtcttatg atgatgtatc gatcgtgcct acatttgtct tgcagccgtt aacttatcta
    11221 ggtggcgttt tctatgccat ctctatgtta ccgccctttt ggcaagctgt ttcaaaagtc
    11281 aatccgatcg tttatatgat ctccggtttc cgttacggat tccttggaac gatcgatgtg
    11341 ccagtagcaa catcgatgat cgtacttgtg ttattcatcg ttgttttgta cgccgttact
    11401 tggtatttga tcaataaagg aagaggattg agaagttaga aaagaggttg tgaaatcagc
    11461 gttttgacct gagtattaga gaaacaaacg ggaaaatagt tcctcatatt ttgttgtttt
    11521 ttgagcgaat accgagggtc agctgattga acaccgttta gtggagaggt tgtgaaaaag
    11581 ctgttctgca tcaagtaata agaacagcca aacaaaaata gctcctccta tttttcgttt
    11641 ggttggactt attaccgcag atgcaagctt ttgaacacca tttattccgg aaaatggact
    11701 gtgataagat ttttgtcaca gtcttttttt tgctcaatca gaaacatctt ttaagctgtt
    11761 cactttgctt ctttttttgt ttcctagtat aatgacaatg tttttgagaa agattgcgac
    11821 ttcactgctt gatagaatgg agagtaacaa ataaatgact actaattttt ggaaagagct
    11881 gccaaagcct ttttttgttt tagcaccaat ggaagatgta acagatgttg tatttcgcca
    11941 tgtcgtaaag catgcagcag caccggatgt cttctttact gagtttacaa actcagacag
    12001 tttctgtcat ccagatggaa aagacagtgt acgaggaaga ttaacattta cagaagatga
    12061 acagccgatg gttgcccata tttggggaga caagccagaa ttttttagag aaatgagcat
    12121 tgctatggca gaaatgggct tccaaggaat cgatatcaac atgggctgcc cagtccctaa
    12181 tgtagcagaa cgtggaaaag gcagtggctt gatccttcgt ccagaagtag cggcacaatt
    12241 gattgaagca gctaaagctg gcggtttgcc tgtcagcgtc aagacgcgta tcggctatac
    12301 ggaaatgtct gagatggaag aatggatcag tcacctactt catcaagata tagccaatct
    12361 ttctgtccat ttgcgtacgc gtaaagagat gagtaaagta gatgcacatt gggaagtcat
    12421 tcctaaaatc attgctttac gtgaccaaat cgctccacaa acactaatca cgatcaatgg
    12481 agatatcccc gatcgccaga caggagaaga attggccgag aaatatggcg ttgatggcat
    12541 catgattggc cgagggattt tcaagaatcc ttatgcattt gaaaaagacc cgagggaaca
    12601 tacagaaaaa gaactgatcg gactacttcg tctgcaacta gatctgcaag atcattattc
    12661 agaaatcatc ccgcgttcca tcacaggact acatcgtttc tttaaaatct atatcaaagg
    12721 atttccagga gcaaatgact tgcgagttca gttgatgaat acgaaatcta ctgatgaagt
    12781 acgagagatc ttagagacct ttgaaaaaga acatccaacg cttttcagtg aacaatgatt
    12841 tcttgcttga acaccgtgaa ttagaggtcg tgaaaaagct gtcctgtatc aagtaataag
    12901 aacagccaaa caaaaatagc tcttcatatt ttgtcgtttt ttgagctaat accgagggtc
    12961 agttgattga acaccgttta tatcagaggt tgtgagcctg ccgtttaact ctgagtcaca
    13021 aggagcaatt tcaaaaaaca gcttctcatg tttgatgaat attttgactt gtgaccgaag
    13081 agttggtagg agaacaccgt ttataagagg ttgtgacaaa agtcttgtcg caacctcttt
    13141 tttaaccaaa aaagtgcaaa tagtttactt taagtaagag aataattatg atgaataaaa
    13201 aaggtggaac aaatagcata ctatatatat tgaaatgaac actgtatgga tgctccaact
    13261 tgatgaagct aaggaggaat tcgtatgtca gaaaaggaat taatgaaggt agtcggtttt
    13321 tatgaagggt tgccgatcga tgatccaaaa agctttattg atgaaaaaga acagatacct
    13381 gtacccagtt cacgggatct tctggtaaaa gtcaacgcag tatctgttaa tcctgtcgat
    13441 acgaaacttc gccaagataa cgggataaga aatgctttac gtatcttagg ttttgatgga
    13501 gtcgggaaag ttgttgctgt aggtgacgaa gtgcaaaaat tttctgtcgg cgatcgcgtt
    13561 ttttacgcag gtacaacaac aagagcagga agcaatcaag aataccaact agttgacgaa
    13621 cgtattgtcg ctcttgcacc aaaaaatctt tcagatgaag aagctgcagc cttgccgttg
    13681 acctcattga ccgcttatga attgttattt gaaaaatttg gtctaactcc agaagaaaat
    13741 gccaatcgcg ggaaaaaaat cttagtgatc aacggatccg ggggcgtcgg ttcgattttg
    13801 aatcaactag cgcattgggc tggcctagaa gtctacgcga ctgcaagtcc gaagaatttt
    13861 gaatggctga aaaaaacagg tgtagactat ccaatcgatt atcatcacga cttaagtaaa
    13921 agttttcgtg aattaggaat cgatcaagta gagtatgtcg ctgtattatt cgatattacc
    13981 cgctactttg atcaaatcaa gcaccttgtc cgaccatttg gacatgtggg aacgatcgta
    14041 gggatcaaag agccgttaga tataggtgtt tggaaaaacc aatctatcag cttcgactgg
    14101 gagtatatgt tcgctaaaac agactataac tatgaaatcg aaacgcaagg agaagcttta
    14161 gcgcacattg ctgctttagc aaatgaaggg attatccgca gtacattgag caaggtctat
    14221 tcagatggga tgaatgcgaa gaacttgaaa caagcaacca aagacgtaga aacaggacat
    14281 atgttaggaa aagtcgttgt tagtggtccg ttcaacggat aagcaagaat acgccgattt
    14341 ttttcttatt tgactttgat aaaaacaaga gcgcatgaca gtaatttgcc ataagctctt
    14401 gtttttttat ttataataag cgaatcaacg aaagggaaag aattcctgcc aagacgatca
    14461 ccaataagct ttttgaaaga atagcagcta aaagtgtagg aactgaagcc aaagcatttt
    14521 cgagattgat ctgcggcaga tgtccgatat tttgggtaaa tagactgctg aaccataaag
    14581 cagacataat gacgatcggg acaaaactta aatactcaag caacggttgc ggtaaatcga
    14641 attttttcag taagacaaat ggtaggaccc tagaaagcca agttgctaaa gtacaaccta
    14701 aaatagtcag caatgtaaac tcaaaagaag gcatgtttga tccacacccc caatccgcac
    14761 ccaatcagtg ttacaactac aatcactaag ttgcttggga taaaaatcag tccgacatat
    14821 accagaatca aagtgagacc aatcaggatc aactgtaatc gtttagaggt gtttctatca
    14881 gaaatgactt gaagataaag taacccgata aacatagcga cgatggcgaa atccaaacca
    14941 aactttttcg gatcagtaat aaaattccct aaaagtgcgc caacaagaga agaacccacc
    15001 cacgtcaaat aagaaatcca attagctgta ttcatccaac gaaagtttaa cttttgtcca
    15061 gtatagttca atttattcat tcccagtgcg aaactttcat ctgtcagcaa tgtgccaatc
    15121 agcagatttt gaagcagccg atttttcttg aaataaggag caatcgtcat actcatcaga
    15181 atcattcggg aattgactag aaaggtcgag aaaacgatgg aaagcaatgg gctgtgacta
    15241 gcaagcatgc tgactgtgat aaattgggca gaaccagcat agaccagcag ggacatcaac
    15301 gtgacgacta gtggatgaaa tccggcagct ttcccaacga taccaaatgc aagtccaata
    15361 ccgatataac cgaaaacggt aggtaacgtg tctttgatcg cagtttttat atctaacttt
    15421 tcatccaata acaaaactcc tttagcacga cataaatttt cataattgtc gttaaacttg
    15481 tgaatattct aaatttttaa tgagcatttg tcaatggtgg gattgaaacg taaagaacta
    15541 gcgggtcgca gatttacacg tattgtttcg gtgggaggag gcgcgaaaaa tcttgcatgg
    15601 ctacaaatcc aagctgatat tttcgatgca acggtctatt gtttaagtgt ggaggaagga
    15661 cctgcattag gcgcaacaat gattgctgca ctagggttag ggtggttcga cacacctgaa
    15721 agttgttgtc agaattttat ccaatataca gatgcagtgg aacctctctt acaaaatgta
    15781 gaaaagtatc ataaaatcta tcaacaatgc cggaaaatct atccagcaac gaaggaaatt
    15841 tgtcatgact tataaaacaa aacgcgtacc taatagtcaa atgactaata ttgggtacgc
    15901 gttaagtctt ctttacttca tcctttgcat gattcgtgtt tttaaagcaa ggtctgctgt
    15961 atttcttgtg gatttaggat ggttgttatc gtttacttgc tatttttcat tgaaatcgtc
    16021 tttctttacc gtttctttag ttttttatct atttttttct tttggttaga aaattctttt
    16081 tcccgaaagt cttctttcag gatttttata gagtagcgtt ttgaataaga ggcgtcagta
    16141 tgatcgactt ggcagacgaa ccaagagaac atttgccttt tttctgcatg aggtgcttct
    16201 gctaataatt ctttccataa ataataacag tcctctatca gaagaagggt tcgttcatcc
    16261 tcaggctccc aatagaatgt ttcgagagta gcaatcactt cattgatcaa ttcgaatgcg
    16321 ggaagatagg cattttgctg aataagcgat tcaactgctt cttggatgaa ctttcgcatc
    16381 tccatgatga acttcgctgt tttcctgttt ttgtttttct tgataatatg atcgtattta
    16441 tggatgatag ttgttaattt atctgaataa tttattgcat gaaatggcat cttaactttg
    16501 aagcgttcga taaagtgcgg atgttctata agaatctctg ttaaaagctc ccgtacaaga
    16561 gaggaactag cggaggaaac aagggacgag agttcggaaa gtgagtagtt ggattttttt
    16621 attggacgtt cttcgtaagc gaataagaca gcagccatgt gtttgcattt ttttccttct
    16681 atggcatata gacaatcaca agtcatgttg gtcttttcat cccaagtgat cactacctta
    16741 taatcttccg tgccagaaac tgttgcggac aagtacttgc ttgtatagtt caaatgacgg
    16801 acaaaaccgt gcagatgata gctgtaaccg cgttccaaaa cgttttcagg aaaatactca
    16861 agccaattat tcatctagtt ctcctttcat gaaacactta tttatattta gtataaagaa
    16921 acgtttaaga aaaaagtagc tgattttaca tatttgataa tcacttttgc tcgaattgtc
    16981 aaaaattcat tctccttttc ttttcttaga gaatgtgaga aaaagtaaaa gaatagcgtg
    17041 ttttaaagat ggaacttttt ttgtttttta tttatctgac aaaaatgaag tgattttgtt
    17101 agaaataaat aattgttcca attgataaaa gaggtatgat gtatcgcaaa ga
//
LOCUS       DAIGWC010000062        16904 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.063, whole genome shotgun sequence.
ACCESSION   DAIGWC010000062 DAIGWC010000000
VERSION     DAIGWC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.063"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..190)
                     /locus_tag="NOB74_002097"
     CDS             complement(<1..190)
                     /locus_tag="NOB74_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221265.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(200..1015)
                     /locus_tag="NOB74_002098"
     CDS             complement(200..1015)
                     /locus_tag="NOB74_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1221266.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1277..1720)
                     /locus_tag="NOB74_002099"
     CDS             complement(1277..1720)
                     /locus_tag="NOB74_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HCI1221267.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1854..2192)
                     /locus_tag="NOB74_002100"
     CDS             complement(1854..2192)
                     /locus_tag="NOB74_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1221268.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2180..2557)
                     /locus_tag="NOB74_002101"
     CDS             complement(2180..2557)
                     /locus_tag="NOB74_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI1221269.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2781..3974
                     /locus_tag="NOB74_002102"
     CDS             2781..3974
                     /locus_tag="NOB74_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1221270.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4140..4562)
                     /locus_tag="NOB74_002103"
     CDS             complement(4140..4562)
                     /locus_tag="NOB74_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1221271.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4957..5151
                     /locus_tag="NOB74_002104"
     CDS             4957..5151
                     /locus_tag="NOB74_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221272.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5148..5642
                     /locus_tag="NOB74_002105"
     CDS             5148..5642
                     /locus_tag="NOB74_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221273.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(5804..6976)
                     /locus_tag="NOB74_002106"
     CDS             complement(5804..6976)
                     /locus_tag="NOB74_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1221274.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7182..7997)
                     /locus_tag="NOB74_002107"
     CDS             complement(7182..7997)
                     /locus_tag="NOB74_002107"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI1221275.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNMI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8147..8593)
                     /locus_tag="NOB74_002108"
     CDS             complement(8147..8593)
                     /locus_tag="NOB74_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HCI1221276.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8590..9594)
                     /locus_tag="NOB74_002109"
     CDS             complement(8590..9594)
                     /locus_tag="NOB74_002109"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI1221277.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9634..9963)
                     /locus_tag="NOB74_002110"
     CDS             complement(9634..9963)
                     /locus_tag="NOB74_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HCI1221278.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10089..12416)
                     /locus_tag="NOB74_002111"
     CDS             complement(10089..12416)
                     /locus_tag="NOB74_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI1221279.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(13259..13552)
                     /locus_tag="NOB74_002112"
     CDS             complement(13259..13552)
                     /locus_tag="NOB74_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HCI1221280.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(13955..15133)
                     /locus_tag="NOB74_002113"
     CDS             complement(13955..15133)
                     /locus_tag="NOB74_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1221281.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(15237..15551)
                     /locus_tag="NOB74_002114"
     CDS             complement(15237..15551)
                     /locus_tag="NOB74_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1221282.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            15658..15873
                     /locus_tag="NOB74_002115"
     CDS             15658..15873
                     /locus_tag="NOB74_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221283.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(16173..16415)
                     /locus_tag="NOB74_002116"
     CDS             complement(16173..16415)
                     /locus_tag="NOB74_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1221284.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(16402..16830)
                     /locus_tag="NOB74_002117"
     CDS             complement(16402..16830)
                     /locus_tag="NOB74_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI1221285.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFLI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         4927 a         3271 c         2936 g         5770 t
ORIGIN      
        1 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
       61 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      121 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      181 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      241 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      301 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      361 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      421 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      481 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      541 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      601 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      661 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      721 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      781 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      841 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
      901 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
      961 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1021 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1081 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1141 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1201 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1261 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1321 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1381 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1441 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1501 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1561 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1621 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1681 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1741 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1801 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1861 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     1921 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     1981 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2041 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2101 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2161 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2221 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2281 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2341 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2401 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2461 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2521 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2581 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2641 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2701 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2761 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2821 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     2881 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     2941 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3001 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3061 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3121 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3181 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3241 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3301 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3361 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3421 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3481 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3541 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3601 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3661 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3721 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3781 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3841 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     3901 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     3961 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4021 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4081 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4141 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4201 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4261 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4321 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4381 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4441 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4501 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4561 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4621 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     4681 aagtattcta ttgatatgaa tcatttaatc gtttattata taaatgtcaa taatctaata
     4741 ataaaataac gtacatattt tattattgca tacttaataa cagaactata gcaaaaaatc
     4801 ccgtgtatca acacgggatt agattaagtt tcctcaatca ctattcataa cacaattatt
     4861 ataacaagta agtaaacaat tgaaaaggac atttattgaa aacggttgtt ttttacttaa
     4921 ggaggaaatt tagcgaaaaa attagttgca ttgtttttgg tcgcaggaag tttgttgagt
     4981 gggtgtggtg ctactacgtc tactactcaa agcacaagtt cagatcaggc ttccagcagc
     5041 agtaccacga tctccgaaag tacggcagat tcatcgaaag aacaagaaca aattgaaaag
     5101 aaaaaagaag agaaacaaaa agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg
     5161 aatctgcttt gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag
     5221 cagctatcca agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg
     5281 attccacaat caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac
     5341 gacaacaagc agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcga
     5401 ggcaagaagc aatcgcacag caacaagcag aacaggcgcg acagcaatca gcagctgaac
     5461 aggcctctca gcaggcacaa gccgcagctc ctgagcaaaa taatgaacaa actgtctatg
     5521 tcacaccgac cggttcaaaa taccatacac ataaatgtgg aaatggtacg tatacccctg
     5581 ccactttaag cgaagctcaa gctcgtggtt taaccccttg ctccaaatgt tatggaaact
     5641 aattcaaaag ttatactata ataataaaat tcttctgaaa cataaaaaaa tagaagatgg
     5701 cgttccagat agtaaaccaa aaataacagt ttacacgtcc atttcgtcag cttctctctt
     5761 ttttcattta gtctgttccc tctgcttttt tggacatctt cattcattct ttctcaatca
     5821 aatagtacac ctctttttct tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa
     5881 actgtttcga atgtttatgt tttacatgga ttttaagcag gagctcctca tgttgcaagc
     5941 gatagttcct gccttttaaa tcagaaaatc tcactagtcc gtattcatca gaagctttca
     6001 caaatggaac tttttctcta gtaatatagt gtttgccgtt gagcgttttt acagaaaaga
     6061 ccattccttc gattggtcgt ccgtttgtgt tctttacata aaaagataaa ggatagtttc
     6121 gcttagcgat ggccaaagaa tctaaataag cgatgagtag ccaaactaag ccgattgatc
     6181 caagtagtat accgataaac caaataaaaa atttccattt tttccattga tcaattcctt
     6241 ggatcgcttt ttttgcctct tttgcttgat aaggaatacg atgccccgtc acaagcagtc
     6301 gatgtgtatt gaccatataa ggagtacagg taagcaaagt cacgagatct ctgccttttt
     6361 ggatacccaa agaatctact tcatcaggta agaccacttg gattttttct acttgatacg
     6421 ccaatgtctt tccattgatc tggatgaaaa actggtctcc ttttttcaac ttaggcaaat
     6481 ctgtaaataa ttttgcttct gggagtccac gatgcccaga aagaacggca tgggtgtttt
     6541 tcccgccagt cggataagaa ctttcttcca ataatgacgt tcctttttgc aaaaatattt
     6601 ccgttgtctg atcgaatata ggtaagctga cattgatttt tgggatttcg atgactccaa
     6661 gcatatgttc cataaaaaag gcattactag gtaaatcttt taatgctttt gcatcaactg
     6721 cttggttgaa actgcctatc cctggtgata cgttttgctc tgccaactgt tggtttttct
     6781 ttgtcatttt ttcctgctgt ttttttattt cctctgaatt cttattcgat gcttgctttt
     6841 gataatggat gatcatttgc tgggcaagaa aatcattcag tgaatcttct acaaaaggat
     6901 aagaaaagat cccgatccca acgactaaaa tgattgccat gaagatgtcc agtattctta
     6961 ttctgctttt attcatcatg tccacctatt ttctaatatg tatatgaaga ggttgtgaaa
     7021 tcagcgcctt gacctgagta ttagcgaagc aaacggcaaa atagttcctc ctattttgcc
     7081 gtttgttgag cgaataccaa gagaccgacc acttgtcaca acctttctcc ccatttgaat
     7141 cactatcgtt tatttatcgt atgatttttg tttccaatag tttaagcttc tgtttcttga
     7201 tggcgttttt tgaaatagat cactgctcct ccaactaaag cagtacctac caagatgaat
     7261 acgatgatcc ccataccacc agttgaaggc aagattcctt taggttggtt atcgatcgtt
     7321 gtttcatcag aagttgttgg atcatcatct actgtaaatt cagtgtacgc agcttcattc
     7381 ttaggtaatg cgtagccttc tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc
     7441 agcccttcga ttgaaaattt cccttctgaa tcagaaatca atttcacttc ttcccagtca
     7501 gaacctgtga cttcatctga ccaagcatat gggtattctc ctgaggcaag gtttgctatt
     7561 tttttcatta atttaacagt tggatctttt gctcttagaa tagaaaattc tgcatcggct
     7621 aatttttctt gcgtgttcac atcttgtttg atgaagtgga aatcaccgta gttttggaca
     7681 ttttctacag taatcatgtt atccgtagtt gtattttccc gattgactac accgtttgga
     7741 ttcccaagat tggcttcatc tgcgccatgg atgataccgg ttgtttgttg caattttccg
     7801 ttttttacta taaaagtagt ttctttttgt ggattggtta attgataacc atctggtgct
     7861 tttgtttcaa ctaaagtata attgccgtct attaatccat tgacactgat ggatccttca
     7921 gtatcagttg tgaatgtcaa cgctgactca gcaggatcat agagagcgac accagtgttt
     7981 tcatcaaaac cggtcacgaa ttgattctct gaatttttga tctggaattg cgcccctgct
     8041 aacttatcta cccctgaaaa gttcccagct ttctggattt tgatattgct ttctttgatg
     8101 acatttttag catataggtg aatcgtgtct aaaggtttgt cagggtctag ggtaagctta
     8161 acacgatatt tggcgacgtt tcgacaccgg gctttggtgt ttctacaaag acgtatacag
     8221 catctttccc atcagattta cctggaagag tcaggttagc taatccttca ccagaagtcg
     8281 ttacacttgc gaagggtgta gcgtctgctg gaactgctgt gtctttactt ggatagtacg
     8341 tagcagtgat gtcatatacg ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg
     8401 tcaattccgt tccgttgttt atttgatttt ctggtgctga agtgaatttc aatttatgca
     8461 aattaaccgt aacattttct ggtgtaggtg atacggctgc agaaacctct gcagttccta
     8521 ggccgagaac gaaaggaagc agcatgatag cagttcctaa aaacgtccat atttttgttt
     8581 tgatgttttt cattttattt ccctcctatt gtttcctttt tgttgttttt tataaaacca
     8641 agctgtccct gttgaaagga ctagcaataa ccctaaaatt gagaaacctc caagcatctc
     8701 ttcgcttgtt tttggaaagc ttcctccatt tttttcattt gatggaccat ttgtctgcat
     8761 ctgaactggc gtttttccat tattcgtcgg atttgctttt ggttcgttga tgatttccaa
     8821 tggtatagga tgaagcggat cataactgcc tttttcaact tcaaagagaa tggttgattg
     8881 actcaatata tatcctttag gcggtttaat ctccactagt tcgtaacttc caaaagacaa
     8941 tccatggaca gaaaatgttc catctttact ggaagtaaaa atcgttgctc ttgaatcatc
     9001 tttggctacc caatgattta tcccgttttc ttgcgctaag tattggtcat tttttttgac
     9061 tagaaattga gcatctgcta gtttttgttt cgtttgccga tccactttga caaattgttt
     9121 gcctcctgtt tggatggcaa gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac
     9181 atcgttatca aatgtcgttt tttcactgtt ttctttcaat gtcatttggt aacggatcgt
     9241 taattttttt ccagcaaacg aactaagatc ttttccagaa tctgataaga caaaaccatg
     9301 ttttattttt tgtgtgtgaa atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt
     9361 ttctggttct agccataact gaggatcagc tgtatctttg atcgtatagg ttcctatctc
     9421 gttgatgttc tcaggaattg ttacggtgat gagataaggg actttatccc catctgcaaa
     9481 atctgtctgc ttattctcta ctgtttttgt taatgtgagt gcagcaggta ttttttgttc
     9541 gctctttgga tacaagtgga tggtcgtcaa tttatgatta gatgaatctg tcacaggaag
     9601 cacaacgaca aatggtgctg atttttcttt tacttaatct gaagtcttta tttccgtaaa
     9661 tcggtaaaca gcgtcacgac cttgctcatc tttgtccgat gcactaaaag aagcaatgcc
     9721 ctcttcctcg tctactgttt ttgtcacatt ttctgccagt attttttcac tatcactttt
     9781 ttgtgctagt tttctttgtg cgtcttccac actacttcct tctgaccgca gcttgtaaaa
     9841 ttcatccgag acatcatata tagcgaaagt aacgccgttc aaccctttta ctccttgaaa
     9901 gttatccggg atatttattc cgtcgttttg actgatactt ggcatcttat cgctttcgaa
     9961 cattcgatta tgcaaagtaa atgtaatagg tgattctcta gctgacacag tcggagaacc
    10021 tataaaaaag accagtagga taaaaaagag aacagcaaat atatccacac gtacattttt
    10081 tgtttttttc atcgctgttc acctgctttt ttcttacgat ggataaaata aaagaagcca
    10141 gaaaaaataa agatcagtcc taaaaagaca aagggcagta gacctatccc acctgtcgaa
    10201 ggaagcaaga gagtcggatt gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa
    10261 ttattgttta cacttccttc gcctaaacta atcgttacta tttgtgatcc aatatctgtc
    10321 cggctgttaa ctgttagggt ataatccaat gattcgccta agacaacacc ggtaacgtgg
    10381 agatttccaa ccgaaatcga gtgactttgg gcatcataat taaaggcagc gtcatcgaca
    10441 gtaatcactg cgttagcttt atagatggta taagttcctg atgtgttggc tatatcagta
    10501 aatgacaact tgggatttgc tgctttgact ttgtctattc cgctattcgt tagtttaatt
    10561 gtatagctgc cagcattaac catatttttt gctgattgtg catctgctgt gtaatccata
    10621 ctgctaagtg ccacttgtac tggagtaagc gaactagtga caccctctgc tagcttgaca
    10681 tggattgacg ggacacctgc ttttccatca tatgtcttac tgccactgag ctctaccgca
    10741 ccgctgattt gcttaatcgt atagacatca gatgtctgca cgatagtaaa taaatagttt
    10801 gttctggcag ctagtttagc tagtccgctt tttgtcaatt gccaagacgt ataggttcca
    10861 atttcagtag gcgcagttac ttcaactccc ttttcattca tcgctttgaa atcagttgga
    10921 ttccatgtga tttgatcaat actgagatca ttgtttaaaa gggatgttga ttctgtttta
    10981 tcattaaagg catatttaac gatcggtaca acagaaagac catcatagta cttactgcca
    11041 tttgcattga ttgatactgt tgcatttgtc ttataatata ggatgacttc agaaatctgt
    11101 tttccatttg cgtcctttac gattacattt ccatttgtat ctaaactagc taaaacactc
    11161 attgctgatt ggttctttgt ttctatcgct gaaacagctg taaaggtata tccgttgata
    11221 gtaggcgtat tagtcgtcag gtcttgtgca gcacttccgt aagtaagatt cattatttta
    11281 gaaggagcaa tcatctgtcc aaaatagtct tgatacttaa tagtgattgg tgtttgtttg
    11341 cctgtatagg tcaccgtatc gacgttactt tctagggctg tgaaagaacc gtttgtttgt
    11401 gcaaaagaat agcccgttac tgctgttgga gtgataacca ctttgtcacc cacatggatt
    11461 ccagataatg tagtcccgta cgttccgatt tttgctgctc caccattgac tgtataagaa
    11521 aaagttcctg tccgattcgc attgacctga accgttgctg cttgataggt tggaaaattt
    11581 gaaacatttc ccttaccatc aacgatctgc ccatttttga tcgagtaccc cgtgaatgga
    11641 atatcatttg ctaactgtat accgattgaa aaagtactca tacctcctcc ggcaggaagc
    11701 cctccccatg ttgagggtgt aaaagaataa cttttatccg cattgggtgt aactgaatcg
    11761 atcgtatttc cagcggtagc cacccccata tagatacttt ttgggaatgt gatagtagta
    11821 ccatttactg tggagccaat aaacagatta tggatatctg gacggttatc aataaaagcg
    11881 attgctttgg ttacgccttg taacgcagtt ttatccgcac tcatcgatcc gttaaccgca
    11941 acaatgactc catctttggc atatatcact gtatatccat ctggtatggt atgtccgttg
    12001 aaattcgcag tggccgcaac agtactaaat gtctggcttc tacctgtttc tgaataagct
    12061 ttctcccctg ctgcttttgc tgctgtgatt tctttttctg tcggatcaat cagttgagtc
    12121 gaggatgtgg ttgaggttgt ctcgttgttg ctagactgat tggtgctttc tatggactgt
    12181 atttcagaat agggtggact atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt
    12241 tctgtataaa cgtttacata aatacttgat aagctcccta agaaagtaaa aatcaagatg
    12301 atcgaaatca taatgggatg taagtatttt cttttagata cagctttgag tctagaaaca
    12361 aaatgttttt gacatatacg ttggatttta ttttgagttt tcttaatcat tttcatccct
    12421 cctctcaata aaaaatcatc aaataatcct ttacacgtta ttctaaattt aatttttatt
    12481 attttattga tgtatagaaa gtttggggct ttttttctct ttttattcta aggttatttt
    12541 agtcttgtcc tttaatacaa agattttatt tttaaataaa aaatactctt tttttacgat
    12601 tattgaaaaa aaaagataaa acttgattaa ttgaagtatt gcttaaattt ggaagctatg
    12661 agggaagaat aaaagagtta ggacgggatt atctactatt tttctttgtt ttaaatattt
    12721 gttatctttg aacataaaag agaaatgtgt cgactgcagt gttgtgtccc tcatcacgaa
    12781 taaacggtgt tcaattagct gatcttgtat tcacttaaaa aatggtaaag tacgagttgc
    12841 tattccccat tttcaatttt ctaacgctca ggacaaaata ctgttttcac aacctcattg
    12901 gaataaaagc atatatattg tttcaagaac gaaatcttgt tatcttttta aagggcatct
    12961 gtccaaaatc taattttagg aggtacgttt tggtatttat tcgtacaaat aaaagagaat
    13021 tatctttatt catgtaacgc atccaattga ttttttcatg tacgctcctg gaacgatttt
    13081 actgacgatt gcttatttaa ctgcgaatcg ctcattagct tttatcatag ctatccatat
    13141 tttgaataac gttcttggct ttgtattata gatacagatg acaaaaaaag ttcaagtatg
    13201 cggtgtagaa ccaatatcgc atacttgaac ttttttcaat gagtataaat taaaacttct
    13261 aattttcaat tcccatcatc tgatatgccc gaccgtctga acttcttttg aaaaagccaa
    13321 atgtgattag ataacgtctt tgttcgacat aatcgccact agaaaatacg ttcagcagta
    13381 tcgaattaac ctctgtttct gtataagtca ctccatggtc aaagcgtttc aagacttctt
    13441 tcaataggat gtatttcttt tttgttgaac ttggtacttg ttttactttt ccatcattca
    13501 tgaatgtgtc taaaactttc atcttttctt gctccgtata agtataaacc atcttctttc
    13561 tccttttgat tctaagaata ctccatttat gttagaatat tctggatttt ttattaaagc
    13621 ggttactctt aagaaagata ttatcatagt gctctttttt ttactactac ttataggtag
    13681 atttattcta atccattatt ctcccctacc aataattaaa gaaaaaactg gatcagggtg
    13741 ttcaaattac atgctaagaa aaaagaaccc ttgaatacca agggttcttt ctcagtctga
    13801 taacaatgat taacgacgga tttctttgat acttgtgaaa agtcgttaaa gtattgatat
    13861 aaaaggattt ttattacctc tgactacata ttgactaatt tgttaaaaaa tcgtttttca
    13921 agaatcctgt aataccagtg ctttcaccgt ttttttaact ctctaaagaa ctaaaagcaa
    13981 tcagaggttt taccttttca tttgacgtta agtggcgata aattttcgaa gttgtttggt
    14041 cagtatggcc taagcgatct ttcaagactt cccagctaca gtgttccgct actaagcttg
    14101 ccattgtatg acgagctaaa tgagtatgaa atggcttatt aattcctgag cgattcacgc
    14161 accgtttgac gtgatcattt acatactctc gacgataagg aacaccacgt ttactagaat
    14221 caagatacac aaacaaatat gtttcttcta taataaacct gtaatgttgc ctcatctcac
    14281 ccaaagcctt aatcaactgt tgtagctttt ccataactag aggagttact agaactcgtc
    14341 tagcagaact aactgtctta gtagtttcaa ttcgaaaatc cttactctta cctttaactg
    14401 ccgtttgctt atagaacaga atttcatttc ttttgaaatc tatatctcca ggctgtagag
    14461 caagcgcctc gctgactcgg cagccagtgt aaaatagaac atggaaaagt acagacatcg
    14521 gtaattcctc atgaacaatg ccataattca aaaaagttct caattcatcg acagtaagaa
    14581 acttgtcctc aatattattt atggcttctt ttaaatcagt taccgttaac tgatattttg
    14641 gcattctcac agacttcatt ggattttcac ttatcaaatt ctttctttga caatatttaa
    14701 aaatcatatt tagaacttga ataagtgatt gtaaactatt tttggcatag ccaacatttg
    14761 ttccattaac gccacattcc tttaaggtaa aaagcaattc ttgaaggcac tctggtgtca
    14821 aatcagacaa ctttttatca ccaatccatc gaacaataat ttttaattgt tcctctcgct
    14881 tatcataggt tatttccttt tgttcattta acgaacggta atattggaac cattgctcac
    14941 ctacaacact aaacttgtca ttgcttgcaa caattttttt cttaagcctt tgttgtttct
    15001 ccatttccag ataagcgagt tgcgcctcac gttttgaatt aaagccacgt cttgttgttc
    15061 gatatgcttg aaagtaccat gtgatcctac cagtagaact gatttgcttc ttgaatcgat
    15121 ctgttttttc catttattga ttcctcctat tttgaaggaa cccaacaagc agaaaccctt
    15181 tggaaatctt tctatctatg tcatcattgt accgcatctt agaaagaaaa tgtaacttat
    15241 aaagatcgaa gtagtcgcaa tttttctcga tagtcattcg aatcactctt tctcatccat
    15301 tctaaaacat catcacgaaa atagtgtcct cgaatcccgt accaacaggg aggaaactca
    15361 ccaagtttta ctaaacggtt cagtgtacta tcacttatct gaaatagtcg ctttaaatca
    15421 gtatttgtta ataccagagg taaatgactg actgcaagca atttttccgt gtaatcttcc
    15481 agtttttttt gtaaaattga atagaactct atttccagag aattaacatt tgttttaact
    15541 tccaactcca tcacccttct ctctcaaaat caaaacgacc accacggtac cccttaaaat
    15601 tgtaaaaaaa cactccagta ctccatcaaa acggactaga aaagaggaat ttttaatatg
    15661 aaacaaggaa ttgcagacat aaaaataatt aaagaaattc ttgaaaaatc tacggctaat
    15721 gcaatagcat tcggaacagg aatcaacttg agtacagtaa aaaaacttaa aagtggagag
    15781 agagctgaag aaaaattaaa tcttgccgat gctattaaaa tcacagaatt tggcatgaaa
    15841 aatatgccaa ccaaaatcga aatatggaaa tagtagtttt tctgatctat cagctgtttt
    15901 gccaaagcac ataggaatct cacctccccc cagtaatggc gggccgattt ggttacggaa
    15961 gtatcattat cgtagtcgcg attctcatat taaaatttgt cgcttaaaag ctaaccttgt
    16021 catggcgtaa ctagagaatc aaaatctaca tgtactgata gatttgctat tcatttgtca
    16081 aagagcgcta ggctattttc agcctatgga aatcctttat tttgacccga taaaaaactt
    16141 ccatagaatg aaaaggaaag ggaaaaaata ctttaacgag ttgtatcaaa ttcaagtatc
    16201 ttctcaatca attttgtttc cagttgtcta cgcatatatt catctacata cataaccatt
    16261 cctttttctt cttcataaac tggtttcatg gctaaccgtg aaatataatt ttgatatttt
    16321 gacagaacga tggacatggc aattgaatca ccagaagctg cggctttgat tgtcgttagt
    16381 ggtatgaatg gtatatatcg tttattttgc ttcatatttg acacccaaat actttcctag
    16441 ctcttccaaa gccatttgtc gttggtacca aacactgccg agacttttcc caataatatc
    16501 gccaatttca cgatcattaa gaccgatgag gaaggacata aaaatgattt cttgtctttg
    16561 actaggtaat gctgcaatcg catttgccaa ctcctcattg gaaataaaga ttttcatacc
    16621 aaggacaata aaagtaccac tactattcaa atttggttcc aaataataga actctgtacc
    16681 taaccctttt tgttccaata tttccattga tatttgccgt tggcgaaatc tagcgtactt
    16741 cttttgaata tttaacgcct cattgcagac tactttctta caaaaactgt caaacgtatg
    16801 ttgaatgtgg gtttcctctg agtcgcccat aatattctcc ccctcaaaaa attcattcaa
    16861 ctcgttttac ttctatccct ttccattatt actacaatct agga
//
LOCUS       DAIGWC010000063        16573 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.064, whole genome shotgun sequence.
ACCESSION   DAIGWC010000063 DAIGWC010000000
VERSION     DAIGWC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.064"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            101..1402
                     /locus_tag="NOB74_002118"
     CDS             101..1402
                     /locus_tag="NOB74_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI1221286.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            complement(1569..3608)
                     /locus_tag="NOB74_002119"
     CDS             complement(1569..3608)
                     /locus_tag="NOB74_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HCI1221287.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDQYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGRKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(3666..4223)
                     /locus_tag="NOB74_002120"
                     /pseudo
     CDS             complement(3666..4223)
                     /locus_tag="NOB74_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            complement(4762..4968)
                     /locus_tag="NOB74_002121"
     CDS             complement(4762..4968)
                     /locus_tag="NOB74_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221288.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(4984..5598)
                     /locus_tag="NOB74_002122"
     CDS             complement(4984..5598)
                     /locus_tag="NOB74_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HCI1221289.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(5745..6428)
                     /locus_tag="NOB74_002123"
     CDS             complement(5745..6428)
                     /locus_tag="NOB74_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCI1221290.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(6537..6995)
                     /locus_tag="NOB74_002124"
     CDS             complement(6537..6995)
                     /locus_tag="NOB74_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HCI1221291.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(7079..8842)
                     /locus_tag="NOB74_002125"
     CDS             complement(7079..8842)
                     /locus_tag="NOB74_002125"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HCI1221292.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(9063..10523)
                     /locus_tag="NOB74_002126"
     CDS             complement(9063..10523)
                     /locus_tag="NOB74_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221293.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(10731..11657)
                     /gene="glsA"
                     /locus_tag="NOB74_002127"
     CDS             complement(10731..11657)
                     /gene="glsA"
                     /locus_tag="NOB74_002127"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HCI1221294.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(11680..13107)
                     /locus_tag="NOB74_002128"
     CDS             complement(11680..13107)
                     /locus_tag="NOB74_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1221295.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(13138..14352)
                     /locus_tag="NOB74_002129"
     CDS             complement(13138..14352)
                     /locus_tag="NOB74_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HCI1221296.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(14693..14935)
                     /locus_tag="NOB74_002130"
     CDS             complement(14693..14935)
                     /locus_tag="NOB74_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI1221297.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(14967..15524)
                     /locus_tag="NOB74_002131"
     CDS             complement(14967..15524)
                     /locus_tag="NOB74_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI1221298.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(15537..15725)
                     /locus_tag="NOB74_002132"
     CDS             complement(15537..15725)
                     /locus_tag="NOB74_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCI1221299.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(15738..16304)
                     /gene="amaP"
                     /locus_tag="NOB74_002133"
     CDS             complement(15738..16304)
                     /gene="amaP"
                     /locus_tag="NOB74_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCI1221300.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4807 a         3434 c         2769 g         5563 t
ORIGIN      
        1 gaaaatcatt ctatcggtcc cttttgagca tgaaaaaaca aaacatacag aagctccgtt
       61 agaattgaat caccacaaca caatcaaagg agcgttctgt atgcctgatc ttcatcatat
      121 caaactacta cttggaatca aagataaaaa cattttcatc acaaatgtgg aatcgaagag
      181 cattaagaat atcaagagtc ttgttgtttc tgcgacgtta agtaaagaaa ttcgtcgctg
      241 tcctttgtgt aaacagatga atcatgaagg catgatcgtt aagaacggaa agaaaaaatc
      301 gctcattcaa cttaataaat gtgcgaacca actgacttat cttgctttag cgaaacaacg
      361 ctaccactgt cgtggctgcc acacctattt tacggcgaat acctacattg tcgatagaaa
      421 ctgctttatc gctaaacaag tgcgctataa aattttagaa gagctaactg aaaaacaagc
      481 aatgacgaca attgctaagc attgcggcgt ttcttggtcg accgtttctc ggacactcgc
      541 ttctctgatc cccatgacaa aagtaaaaag aaattggtta ccgcgttgtt tattaatgga
      601 tgaatttcgt tcactgaaaa atcaagtcgg tccctactcc ttttcttgta tggatggcga
      661 tactggaaaa ttactggata ttcttccttc acggaagaaa aaggctctcg tttcttattt
      721 tatgcaattt gaacgacgcg cacgattgaa ggtaaaggtc atcgtgacgg acatgaatgt
      781 ttcttatgcc tctctgataa aggaatgttt tccaaaggca aaactcgttg tggatcgttt
      841 tcacattgtc aaacatctca ttcgtaaatt tgaggatatt cgcgtacgaa tcatgaaaag
      901 ctttgatcga aacgatccaa cacaagccaa atattatcga caattaaagg cgttgtctcg
      961 gcttctgatc aaacgacagg acaagcttgt ttatgacaaa tggaccaaat ggcgcaattt
     1021 tggttgggcg tatctcaccg aaagtgaagt ggtggatcgt ctgctttcga tctctgacga
     1081 attacgaatc gcctattttt actatcaaga aattcttcaa gcgtttcacg acaaagaggc
     1141 ggacactttc tttaaacttg taagaacgat gcccaattcc gttccaaaag aactgcattc
     1201 tataaaaaaa gcttttataa actatgaatc cggcattcgt ttagccctcg aattgcctta
     1261 ttcaaatgcc aaaatagaaa atctgcatac ccacatcaaa gcattgaaac gagtcgctta
     1321 tggctttcga agctttcgga aaatgaagac cagaattttc ttactaaata atctgattac
     1381 ctatgaatca aaaaacatct aaagtagaaa aggaattcta ccttagatgt tcttatctca
     1441 ctctatcagt cctatttgac aaagagccaa aagaagttgt gaaagagaca tcgtgaaaac
     1501 cgtttatttg aaaaaaggac tgtgacgata acgccacagt ccttttactg tacttaaaaa
     1561 gcaatttttt attgataatt ttggttgagg tattgcaata gttccgatgc tcgtttggtt
     1621 gctgaatcat catcttcttt attttccaac atgctgacca tcatataacc ttggttatca
     1681 agattgaaag caaacaagaa actgttctct tgccccttta catcctgttt ttctttgatt
     1741 tccgctgtac cagttttcgc tgccaacgga atccctaaag cagaaagaga atgtgctgta
     1801 ccatttacat cttgcacaac ttctctcaga tctggcacga tcgtttgtac tgctgtttcg
     1861 ctgatgacat tcttcttatc ttttgtctct ttatctgcaa tcaatttagg atagacaagt
     1921 gtgccattgt tggtaaaaac agaatacatt gctgcttgct ggataggagt aattagaagt
     1981 tcgccctgtc catatccagt atcagctagc aagatatctg agttaaagct atcttcatta
     2041 gaaatttgtg ctggattcat actaattggc aaatcaaggt cttcaccaaa aatgaattta
     2101 tctaagcctg tacgaaattt tttctcaccc attttcaacg tttcttgtgc cgcatatata
     2161 ttatcggaat agatcaaagc agtttttaag tctacttgtg atacatcact actgacacgc
     2221 gttgttttaa aagatcccca agaactgtct ttttgccatt taagcccgtt gatcgtcaac
     2281 acttcatttg gatcgatagt gccgttgtcg agaccgattg ctgctgtaat tattttaaac
     2341 gtagatccag gagcataacc tgtcgcaaat cggctgatga atggatgttc aggattttct
     2401 tcataagctt tgtaatcttc ttgtgagatc ccgtttgtca ttttgtttgg atcatagctt
     2461 ggagagctag caagcgcaag aagatcaccg gtttttggcg ttgtcgcaac agttgatcca
     2521 gcttttcctc ctagactgtc aaaagctgtt ttttgtgcct tcgcatcgat tgtcaatttg
     2581 atatctttgc cattttgaac ttcatgttcg atcagaactt ttttctctac accgtctgca
     2641 tctgtaatgc ttaatttcct acctgttgtc ccacgaagat ccttatcaaa agccatctcc
     2701 aaacctgagc gaccgatttt tccattactg cttaattctg gattcttatc aatatcttct
     2761 gctgtgatat ctcccacgta accaatcagc tgagcagctg cttcacccaa aggataatat
     2821 ctgccgtcta cttcttgaat ggtagctcca gctggaagtt ctggcgttgc tccatcaatg
     2881 attttcaatg ggacaaagta atcgggttgt acccagcttt gtgaaatcgc ctgattgata
     2941 gcatcttctg ttaagtcgaa ggaggaagca atcgctttga tattggctgt tttttcgcct
     3001 ccatctccaa gtttacttgg aacgactcct aattgtttta gtttgcctgt tgttgctaat
     3061 ggttcaccat ttcgatctat aatattccct cttgctgctt cttgtgtggt caggcttact
     3121 ttgtcatttc cttccatttc tggaaaaacc aagttgggtt gccagttgat cgtggtttga
     3181 ccatcatttc tgtctaatgt tcctttataa gaaagatctt tcaattcacc taatgaggta
     3241 ttcatctttg ctttatatga aaaactgtaa gtagaatcgt cttttttatc tacttttaga
     3301 ttcgatatct gaagtccttt gacatcagca gcaccgtata tattctggta ttgatctaag
     3361 atctcttttt cagataatgc acttttattt gccgcctttt ttgatgtcat ttctgcagct
     3421 ttgttataat ctcccttgtt caaagcttgg acaaattgct caactgtctt ttctccagct
     3481 tctactgctt gggtttcttg atagtgctgg tagtaaaaat aaccgccacc cgcagctgct
     3541 attaagatca ctgcgccggc aatataagcg cctgttcgat ttttgccgtg cttgtcactt
     3601 cttttcattt tttcctcctt ctcttgcttg tcattccttt atttcactat ttatacctgt
     3661 ttattctaac atatgtcttt gaggaaatcc ataccacaat ccagaagcac actttctgga
     3721 aggttcgttt ggatactacc aagtaatttc ccaaccgctt tgggtagctt gaatattgaa
     3781 gttacgtctt tcagctgctg agagatagct ttgatcactt gctgctgcct tctgatcctc
     3841 ccgaagtctc cttctttgtc ttcccgaaat cgagcatact ggagtaaagt attaccatcc
     3901 atcacttgct ctcctttgtt tatatatacg ccatctaaat ctagagattt ttctgcatcg
     3961 atcttgactc caccaggaaa cagttcatta acgcaatcga taaaatcttg aaatgtgata
     4021 cttgcataat agggagcttc aaatttgaaa ttttccttta atgtttgatt taataaatca
     4081 actcccccat aagagtaagc tgcatttatc ttattcattc cgtaacctgg aatatcgaca
     4141 tatgaatctc tcatgataga gatcagtttt gcttgttgtg ttttctggtt gtattgtgca
     4201 accagaagtg aatccgagcg acctccacca atcgatcttt tttcaccgca tctcctcctc
     4261 acacagcaat ccacttgtca ggtgaggagc gagtttgtct catcaaataa gtcagtcaca
     4321 aaaatataaa gaaaaggtca gaaacctttt cgaacaagaa ttctgaccta gcatcatctc
     4381 atcgtccgag ttttagcact atacaacgta aagaaaacat tcttagctat tggaaaaagc
     4441 cttaatccaa cagtttctgt tttacccatt ggcgactttc gacgtttctg ggcaacagcc
     4501 tatgtttgta taggagcctc acctaacaag gttattacta tattctattt acgagttcat
     4561 gatagacttt tcctaatgat taggcaatgg aatttgaaat gaaatagtga aatttaacaa
     4621 tctttaatat tttttagaaa aaaataacaa ataagttgaa agaatcccgt tgcaaattct
     4681 ttcagttgca ccaggattct ttgataattt tttagtttta tgtgtttttt tatatgtttt
     4741 ttcacttttc ggaataaata tttatttgtt aaagtaatta aacaatccgc taatcgtttg
     4801 atctggcatt tctatttcct taccatctaa agtaacagta gtaacgacaa aatggtcttg
     4861 caatggcgga acttctaagt actgcccttg cagaaaatca ttcactgttt catattcttt
     4921 tttcatttct tttgaatctg tcgatggttt atagcttatt tttaacataa ctagtgctcc
     4981 tttttattcg ggacgtgcaa tcgtgaaaat ttctcctatt gctgcataat catttcctgc
     5041 caaacggctt acagcattca attttcttgg atcgatcctt cctgtcttat catcatagac
     5101 tgtttcattt aaatgatatt tctgtacttc tagcaaaaat aaatcagctg ttactttatt
     5161 tttattccgt atctcgacat gttcatataa ggatgtttca aaacgaactt ttgcttctgt
     5221 caatgctggt actgaaatga ttactgaatc agttaaagtc aagtcagtca ggtacagttc
     5281 gctttcctca ttaggcagat tggctgctgt tttatttact tcttctacgt tgtcctcatc
     5341 aaggatatgg ataacagctt ctcttgtctc aagaatattc tttgctgtgt cttttactgc
     5401 atcttgtttt ctctggatcg ccaaggataa gatgggtcga ttcgaactga cgatattgaa
     5461 gtaactgaag ggtgcgatat tcactatatc ttttgctgat ttagtcgtta ctactgctac
     5521 tggtctaggg atgactgaac caatcagcaa cttgtaattt tcacgttctg tcaattctga
     5581 aggactccgt tcaaacatgg tttcgccttc tttctataaa attcgttaaa aagcagatct
     5641 tgaagacaaa atgaaaagta atgctttttt catcttctta gaatctgctt taaactatct
     5701 atcaattttt cttttttgtc aagaatctgt gccgtgcgtg ttttttagtt atttgcttta
     5761 cttgcggctt cgacatatct tttagtgatc aattgcggac gggtgataat agatccaact
     5821 acgactgaaa aagcacctaa ttcatatgct ttctctactt gttcaggaga gtcagtatgt
     5881 ccttccataa ttactgggat atcgacttgt tctatgattt gattcaataa atcaaaatca
     5941 ggtgtctgcg tctttcgtga atattctgta tagcctgcta aagtcgtaga caaaagatca
     6001 aaaccatctt cttgcgcttg aagcgcttcc tcaaaagtcg aaatatctgc catagctaac
     6061 cgaccgtgtt cgtgaatcat ttggacaagt tcagcagttg ttttttctgt cggacgttta
     6121 cgagaagttg catccagtgc aatgatttct gcttgcgtct ccaaaagttc ttccacttct
     6181 ttttctgtcg cagtaataaa cacttctgac ccatcgtaat ctcttttgat aatccctatt
     6241 accggtaaat caacgattcg cttgatttca ttgatatctt ctgtcgtatt tgctcgaata
     6301 ccaactgctc cgccttcttt tgcagccaaa gccattctcc ccataataaa agaactgtgt
     6361 agcggctcgt tttccaaagc ttgacaagaa acgacgactc cgcctttgat ttgttccagt
     6421 gtatccacaa tatctcctcc agtaatgtta tataaaaata cagcttcata taaaaatgta
     6481 acccttttct attcaggaga caataatgag ctatttcttt cagcagacct ttcttactaa
     6541 aagaaaatta cttcaaattc ttcgtatacg accagcttct cttctgtaaa ttctatgttc
     6601 aacgcttctt tataagcatg tttaaaaaac tcagcatgga ctttccgcca ataagctaat
     6661 gtccgatccc cttctccttc tttccaagca tgctctttcg tgacttcact aaaaggcaag
     6721 atggtcacat ttatattttt gatgatacaa actggttcat tttttccatt caggaccacg
     6781 tctaattgac caacttttgg taaaggctca ttctcttgtt tatacagatc gtaaccactt
     6841 gatgtaccag tctttatctt ttttacaact agttcgctca actcgtctgc cattttttct
     6901 gtatccccaa atgaaaagaa acctaatttt tctgattgat aactaggata tttttcttgg
     6961 aactttttga catattcttc tacttgctga tacataacat ccaccccttt gctttttata
     7021 atgaaaaaac catccagata ctagtataaa caattatctg gatggtgagc ataatgaatt
     7081 attgaatatt caagacacgc agactatctt caacgatttg ttttggtgtt aaatgataac
     7141 gttcataaag ctgccctaca ggaacgctat ccgtgaattc tttctctgca ccaaaattta
     7201 atacgttcat tgaagaatca ccataataac gactgatatt ttcgccaaat cctcctgaca
     7261 aactaccatc ttctaatgtg atgactaatt cgtgtgtttc ttttaattta tctaatgttt
     7321 ctacgtcatt ttctgtgatc gttcctggat tgatcaacgt tgcttcgatt cctttttttc
     7381 taaaagcttt tactgtttct tttcctaatt caagaaaacc gcctaaagct aaaattgcta
     7441 cttttcctcc attatttact gtttgatagg ctggaatact ataatcattt gcgatagctg
     7501 taccatgttc tacaccatgt gtaggaattc ggattgctac aggctgcgct gtttgttcga
     7561 acgcccaatc tagcatagag atcatatcct cttttgttgc tggagcaaga tatttgatgt
     7621 tcgggatact tgataagtaa ggaatgtcaa atgttccttg gtgtgttcgg tcactagctg
     7681 agatcgttcc gccaccgact aaaataatca ctggattctc gttgatcgct aaatcatgtg
     7741 ataattgatc atatgcccgt tgcaagaaag tacttgattg gaagacgact ggacgtactc
     7801 cctgagaagc caaagcagaa gcgaaagtga tagagtgctg ttcagcgatc cccacgtcaa
     7861 aataatgatc tggatgtttt tcttggaatg ttttcagtcc aaaggcgcct ggtatcgctg
     7921 cattgactgc ggcaatagga gctgtacttg tttgcatttt cttatccaaa taatccatga
     7981 tgatcatatt aaatgtttct ccagaagtta cttgctttgc ctccccggtg gacagatcaa
     8041 atggtacatg ccaatgatat ttcattttat tatcgattgc cggctgataa ccgcgacctt
     8101 tttccgtatg gacgtgaagt acaatcggat gatcaatatc ttttacttct tcaaataaac
     8161 ggatcaccgt ttccagatcg tttccattat ccacgtaacg ataatcaaat cccattgctt
     8221 taaataggtt attgctgctt ttaccgttgg tttgacgaag ctcagctaag tttttatata
     8281 aactgccatg attctcatca atagacatct cattatcgtt tactaatacg attagattgg
     8341 attgtaaaac accaccattg ttcaatcctt caaaagctaa gccaccactt agggagccgt
     8401 caccgataaa tgctaccaca tttcctgatt ctttcttcag atctctcgct ttagctaaac
     8461 ctgttgctaa gctgatagat gtagatgtgt gccccactgt aaaatagtca tgtttacttt
     8521 catgttggtt ggaatatccg ctcacttcac ggtaatgtcc tttttcaaaa ccattttttc
     8581 gaccagttaa aagcttatga ccataagact gatgggaaac atcccaaacg attttatcct
     8641 ttggtgaatc aaatacataa tgaaacgcaa tcgttaattc tactacacct agattcggac
     8701 caacgtgccc acctacatcg ctgtcctttt gcaagatttt ttggcgcatc tcttctgcca
     8761 actgtttcat ttcctcaaca gataattttt tgacatctgc ggggctattg attgcatcca
     8821 atacatgtaa tactgtactc ataatacatt ctctcctccg tactatcttc ttttaatgaa
     8881 aatagatttg ttacacttta tctattctac tacttagagt tgactctaag tcaatagcat
     8941 tttaaaaaaa tttcagagaa agcttgttat ataagtagat cttcgcacga atcaggactc
     9001 aaataaaaac cttctacaga caattaaaaa gctttgtaga aggtctccta attaaggtct
     9061 catcaagaaa tatgtttttt taataggtga agttcctgag caatatgata caaatggatg
     9121 tttgcacctt ttaatgagat tggatagatc tttgtctttt cagtttctaa tccattttga
     9181 tagctagcag catcgcacaa aaccactctt tttttcgcac atagacattc atcaggcaat
     9241 tcttctaatg aacgaaataa aataggattt atttcagcga tgccttcttc cgcatacaaa
     9301 tgaaattggg ttcgataaaa aaattgtttg actgaacttt ctgaaacaac aaaaatttct
     9361 atttcctgtc tccccgcttg ttcactgttg atcaaagaaa gacttttgac gaattttcga
     9421 atgaaatttt cattccatct tagttggatt tgatttttct ttttccactc ttccaatatt
     9481 tctacaattt ttccgtacag aagttgttct ttttctgata gaagatagat cctttccggt
     9541 aaaaatactt gtccatctgc ccacaacgta cggacaaatt gtaaaaagga ttgcttgaaa
     9601 ataaaatttt ctgcatcgtc gatttcagcg atactaataa tctgtaaaat caattcattc
     9661 agtgataggt cattgagaac aaaattttta taaacaactt cgaaatcttt tcttaacagc
     9721 tccatgttct cattggtata atttctactg ttgaacaaag aaaaaatata atagacatct
     9781 tcttcttgta agtctagaat tcctttttgc tcttccaatc cttgacagac taattgaaat
     9841 aacggcttcg tttctgcgct tttcttatct tcttctttca gtccaagggg aaatgccttt
     9901 cttccgattg cgatctctat tcctcgtatg ataaaggact tttcatcttc cgaatatctt
     9961 cttttaaaaa aatgagtctc tacataatca atcaactcgt tacaagcttc ttctacatac
    10021 ggatttttat tttcatagcc ttcccaattg acataacgta ctaaagctag caagatgttc
    10081 cgcgagtcaa attctgggat aatgatttct ttatttttca aataatcatt ttctttaaaa
    10141 aaatccaata cgattttttt gattgtatat actttgctca aagaaataaa ttcaagatca
    10201 gccagttctg tactcgtgaa tataccatta aaataataac ttaaaaactt taaaaaataa
    10261 gattgaccgt acagaaactg tgtgagctca gaaagagcaa taccatgttt gaatacgagt
    10321 ttatacttat gcttctctct tacttgttct tttatacaat attctagaca ctcggctaga
    10381 ctttctagat cgtgaaggat cgttggtgta gtcaccctta gagaaatagc tgtttgttcg
    10441 atgtctattt cttggaattc aaataattgt tcacacagat acacttttct aaatatattt
    10501 cgctcgatgt aattttccag cattcctgat acacgcctcc agtttttctt atgattttat
    10561 ttaatcatat ctgtaaatcg tatttttgtt tcctttttat ttagaaaagc cctttcaaaa
    10621 accaataaaa aaagaaactg ggacaaaagt caaacaagct cacaatttca gcctcattgt
    10681 aggtagcttt gagccgtttg gacttttacc ccagcctctt tcaagaatgg ttattcaaag
    10741 atgtcagcgt ctagttcttt gactacatct ttcaacaatt ggataccagc tgcgctgtta
    10801 ccaaatggat ctagtgccgg gctgaagaca cctatgccgt aacgatttgg cacagctgcc
    10861 atcaacccgc cgcctacacc gctttttgca ggtacaccaa catggacgga aaactctcct
    10921 gattcatcat acaaaccagc agttgtcata attgatttga cgattgtagc actttcttca
    10981 gtaatgattt gtttgccatt ccaaggagca attcctttat ttgccagcac agcagctaat
    11041 tttgctatgc ctgtagcggt gacattgagg gagcattgtc tgaaataagc atcgagtatc
    11101 tccggtacgt ctccttcgat catttgatta cctttcatat agtaagcaag agagcgattg
    11161 atatcacctg ttcttgattc agaatgatag atttcttcat tcaatgtgat attaggatca
    11221 tcacagatct ctttcataaa tgacaagatt cgctcaaatt tttcatctgc atctttaccg
    11281 gcaatcaacg aggttgttgc aatcgctcct gcattaacaa aaggattcat tggatgtttg
    11341 cgatgattga tttccatatt catgatagaa ttgaaggcaa aaccggttgg ttccgtgttg
    11401 attgtttgaa agactttttc tattccgttg tctttgattg ctaataacaa tacgggaact
    11461 tttgacatgc tttcgatggc aaagcgcaca tcggcgtctc ctccctcaat cagttgtttt
    11521 gtatccaaat cataaatcgc catacctaat tgtttgggat ccacttcagc taatgctgga
    11581 atgtaatccg ccacttgtcc tgtttgataa tagtggaaat tttttccaat caattgttct
    11641 aattctttta cttccatttg aataaccagc tttcattttt tatttttctg catgctggaa
    11701 tttatgacgg catgcgtaga tcgtaaatgg aataactaag acgataagat aagaaacaat
    11761 cagaatcgtt tcataaatcc catgctgtcc agctgcgata ctagcaggtg gaacaaatga
    11821 gatacaaaaa gcaaaaagtg aagtcaaaag acctaaacaa gcaacgatta cttttacaac
    11881 ttttccgcct ggaacctgat aggctctttc aagactgtca tctttaaaaa ccagcttcaa
    11941 atagcccgcg aaaaacataa agtacaacat caggtagatt acaacagtca atgacatcgc
    12001 tgcaagaaat gaaagattat tccccccgcc gcttaatgta aagacggctg cccagattgt
    12061 tgcaacgatc ccatttgcga tcatcaaatg agcaggaaca ccgtgtgtgt tttcttttgc
    12121 aaaatattca ggaagtaatc cttcttctgc tgctacgtga agtgcttttg aaggagaggt
    12181 tacccaagaa gcaatttctc cgatgacacc taaacaaaca agaatcgcaa gaattttcgc
    12241 aatccatgca agatttggat caatgtgtct taataggaat tctaacgatt gaatcacccc
    12301 tgtattaaga gacaaaccat gttgaggtac tgtagtagcg acggtcaatc cgccaaaagt
    12361 atctaaaatg attgccagaa taaccaatac aaacattgct aatggataat cctttttagg
    12421 gttttccatt tcatttgcat gactggcaga tgtttctacg cccatatatg ctaaaataaa
    12481 ggaaacaaaa acaaccagcg taggcaattt cgaaaaatca ggaatcaatg ttttcataga
    12541 cagtatcgtt tgtagtggag cgcctgaagc gacataatgg atccctaagc caaacaagac
    12601 taatgctggc aacaagatac cagctacaaa accgatccga gcaatcaatg aagtgtattt
    12661 ggttcctttt aactgtgaga gtaaaatagc ccagaaaata atcaatagga ttgccaattt
    12721 cagatattta ttgttttgta tagcaccaat acccgttgca taggataatg caccagttaa
    12781 gaaatacagc atggtcaagt agccaactgt tatctcaaac cattggaaaa agattgcggc
    12841 aaaaccgaat cgttttccca atgtgcgact gacccaagta tagacaccgc ctttttccca
    12901 tcctttcacc gttgccatct ctgctgcgca caatgccaca gggataaacc atagcaaacc
    12961 gcctaataac aagaaaaata ctaagctgaa gcctgaggtc gcgaatgtgg gatattcata
    13021 taatgaaacg accattgaga tggtcatagc caaaaagcca aagaacgtta atttttttgc
    13081 aggaattttc gttttgcttt gttgcatgaa tcttcctctt ttctatttga atttgtttca
    13141 attgagtttg ttgccaaaga agaaaaagtc caatccttct tcttgttctt cttttgtagt
    13201 agtgatcgtt gtaaagtgca tcgccgattt taaaatcact gttgtcagca cataggcata
    13261 cacggcagta atgatgacac caatcacttg aatccctaag aagtaccagc tgcttggatt
    13321 cgttagtaaa tggctgttag atgcaaagat ccctatcaga atcgtacctg tgaatccgcc
    13381 catgccatga acaccccaca catcaagtgc atcatcccat tgtttctttt tacgaaaatc
    13441 aacagcagca tgacagacga tacccgcaat gatcccaatc agcatggcac tttttgcttc
    13501 tacataaccg gcacaaggcg taatggctgc caatccagca acggatcctg ttagtacgtc
    13561 gacaaaatca aagccatttc cttttacttt tgcaatgatc agccaagtaa tcatcgcaaa
    13621 tgcaagagcg atgaatgttg aaccaaatgc attgactgct tgttcatctg ctcgaagtgc
    13681 accaccggaa ttaaaaccga accagccaaa ccaaagcagt cctgtaccga tagcagctgc
    13741 cataagactg ctatgctgac ttctttctcc taaaggaatc tttctttgac caagtgtgag
    13801 gatacatgct aaagagccga atccagctgt cgtgtggatg actgctccac cagcgaaatc
    13861 tctaaatccc atctgatcca aaaatccgcc accccatatc cagtggcaaa cagggaaata
    13921 aatcagcaga ttccaaaaaa taacaagtat aatatagcct tttaaattca atctccctgc
    13981 aaaagctcct gtcatcaaag gaacggtaat cacgataaac atcagttggt aaagaaagaa
    14041 cattaaaaat ggaatcgttg caccatgaaa catgttgggg aagcttgtaa catgtctcat
    14101 caaaaagaaa tctgccgggt ttccaataac accgccgata tcccgtccaa aggccaatcc
    14161 gaatccacca aatacccaca taatcgttgt tatcccaacg gagagaaaag attgagacat
    14221 gatcgttagt atattattct tccgtgctaa tccgccgtaa aaaaaagcta gaccaggagt
    14281 catcaggcaa accattgctg tacataaaat catgaatgct gtatctcctg tattgatagg
    14341 taatgtattc atttttttcg cctcctttct acgattacga gtataaaaga aggtgtagtt
    14401 gtttttttct tctgtttttt tgaattaata cttgcattta taaaagacag acaattaata
    14461 aaagcttgat gtgttgtgct ctttttcgtt tttcacacaa ataaagacaa aaaataaacg
    14521 gtcttctttt tatagaaaac cgtttatttt cgtctttttt tatttttaaa gatatttttt
    14581 cataaggaat aaagaatact tcatataaaa tatataaaaa agaaccgcag cgagtgtcgc
    14641 tacggttctc aaatttgttc ttcatttcaa cataagtttt tcttcaattt gcttataatt
    14701 tacgtgcaaa gaatgaaacg actaatacta aaatgattgc accgatcaat gatggaatga
    14761 tagccattcc tgcaattgtt ggtccccaag ttcctagtaa agcttgtcca attgctgaac
    14821 ctactaaacc agcaatgatg tttgcgatga tccccattga tgatccttta ttcgtgattg
    14881 ctcctgcaat tgctccaatg ataccgccga cgattaatgc ccaaataaat cccattttaa
    14941 attcctccta actgacttct tacttcttat tgtacacgtg gttcgttatt ttctttgact
    15001 ttttgtgcac ctttgcctac agcagatttt gctttatctg tttggcgtga agcaaattgt
    15061 cctgtggatt ttgctgcttc tgttactttg tcttgtactg tttcttgatc tttttggtat
    15121 tcttcttgtg ttttgatgtc tgcaacattc acattcactt cgataacatc taaatgtgtc
    15181 atattgttta cttcagtact gatcaattct ttgatttggt tgtaaatatc ttcgatgtct
    15241 ttaccgtatt ctacgatcac atctagatcc acagctactt gtttcttacc tacttctgta
    15301 ttgatacctg ctgttacgtt atctgtgttg actaattttt cagccatatt tgagaaaaat
    15361 ccgccatcta atgtcaatag accatctaca tctttcaatg cataaccgat gattttttgg
    15421 atgactttgt cttcataagt caattcacca ttcatcatgc ggttttctcc tttttcattt
    15481 gccaaaactg atccatttgt tgtattcatg tttttgtttt ccatctttgt ttcctcctat
    15541 gatttaaaaa attgatcaac tattcctgac tgtttcaaat aaaaaccgat tcctgcgcca
    15601 attgctgtca tgattatgat caacaatgtc ttgaaaaatc caatcgttaa ccataaaaca
    15661 gctagcagta gtccaagacc cccaaagata atagggagct tgtatgctga aaatagttct
    15721 ttcattattt ggccctccta ttccactcga gagtgcttgt agtctcttgt atcttcttgt
    15781 tcttcataac cgctgtatgt gactgccact ttgaccgttt cttttgttcc gagtacttta
    15841 gttacttctt cttcgatatc ttgcatcaat acacctgttt tccctactaa tgaagaagtt
    15901 cgtttcaagt ctccgttgac atggatatgg attcgatttt tcgttgaacg tatccgtact
    15961 ttaggtgaat gaatgaactc ttcttcgtgt aaatgggaac gtaccaaccc ttcgatcgct
    16021 tttttgtcga ttgttagttt gccatcttcc cgtttcataa cgaaagttcc tcttgacttt
    16081 ggatagaaaa gaacgactag caagatgata atagcaagaa cggcaaatac tacagctgcc
    16141 cagaaaatat attgttgcat gtagtaattc gttaaagtaa agaagcgaaa tcgttccaat
    16201 tgttcaggca taatatacgg cgcattgatc aacgcaatcg ctagaaatac tgaaagtagc
    16261 agtaaactca tgataacacc gattattttt aaccccttat tcattttcca cctcctataa
    16321 acttattttt accctgtaaa taactctacc gacaatcaca gtatagatag cgaacagtta
    16381 gcatagcatc agtaaataaa gcgctaccaa acattgctgg atcataacgg cgttttattg
    16441 ccagtctgat actgaaataa caattgctta cttattctct atttactttt gattgctggc
    16501 tatacttaaa ggatattatt caagattaaa aattgcaaag attatgctca gttattatta
    16561 caagattcta ttt
//
LOCUS       DAIGWC010000064        15229 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.065, whole genome shotgun sequence.
ACCESSION   DAIGWC010000064 DAIGWC010000000
VERSION     DAIGWC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.065"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            278..787
                     /locus_tag="NOB74_002134"
     CDS             278..787
                     /locus_tag="NOB74_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1221301.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="NOB74_002135"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="NOB74_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI1221302.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="NOB74_002136"
     CDS             2322..3302
                     /locus_tag="NOB74_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1221303.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="NOB74_002137"
     CDS             3424..4842
                     /locus_tag="NOB74_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HCI1221304.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="NOB74_002138"
     CDS             4913..6382
                     /locus_tag="NOB74_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1221305.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="NOB74_002139"
     CDS             6392..6859
                     /locus_tag="NOB74_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1221306.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="NOB74_002140"
     CDS             6895..7767
                     /locus_tag="NOB74_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI1221307.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="NOB74_002141"
     CDS             7848..10382
                     /locus_tag="NOB74_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI1221308.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="NOB74_002142"
     CDS             10538..11311
                     /locus_tag="NOB74_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1221309.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="NOB74_002143"
     CDS             11304..12095
                     /locus_tag="NOB74_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI1221310.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="NOB74_002144"
     CDS             12105..12596
                     /locus_tag="NOB74_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1221311.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="NOB74_002145"
     CDS             12614..13024
                     /locus_tag="NOB74_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1221312.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="NOB74_002146"
     CDS             13028..14428
                     /locus_tag="NOB74_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HCI1221313.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="NOB74_002147"
     CDS             14451..14825
                     /locus_tag="NOB74_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI1221314.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5286 a         2135 c         3045 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactccta
//
LOCUS       DAIGWC010000065        15137 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.066, whole genome shotgun sequence.
ACCESSION   DAIGWC010000065 DAIGWC010000000
VERSION     DAIGWC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.066"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            5..2377
                     /locus_tag="NOB74_002148"
     CDS             5..2377
                     /locus_tag="NOB74_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221315.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="NOB74_002149"
     CDS             2438..3898
                     /locus_tag="NOB74_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HCI1221316.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /gene="topB"
                     /locus_tag="NOB74_002150"
     CDS             3909..6113
                     /gene="topB"
                     /locus_tag="NOB74_002150"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI1221317.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6129..6278
                     /locus_tag="NOB74_002151"
     CDS             6129..6278
                     /locus_tag="NOB74_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221318.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6353..6946
                     /locus_tag="NOB74_002152"
     CDS             6353..6946
                     /locus_tag="NOB74_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HCI1221319.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6959..7858
                     /locus_tag="NOB74_002153"
     CDS             6959..7858
                     /locus_tag="NOB74_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HCI1221320.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7861..8358
                     /gene="ssb"
                     /locus_tag="NOB74_002154"
     CDS             7861..8358
                     /gene="ssb"
                     /locus_tag="NOB74_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCI1221321.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8724..8984
                     /locus_tag="NOB74_002155"
     CDS             8724..8984
                     /locus_tag="NOB74_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221322.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9429..9635
                     /locus_tag="NOB74_002156"
     CDS             9429..9635
                     /locus_tag="NOB74_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HCI1221323.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9635..9886
                     /locus_tag="NOB74_002157"
     CDS             9635..9886
                     /locus_tag="NOB74_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221324.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            9902..10339
                     /locus_tag="NOB74_002158"
     CDS             9902..10339
                     /locus_tag="NOB74_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221325.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            10332..11039
                     /locus_tag="NOB74_002159"
     CDS             10332..11039
                     /locus_tag="NOB74_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221326.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11419..11598
                     /locus_tag="NOB74_002160"
     CDS             11419..11598
                     /locus_tag="NOB74_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221327.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11923..12186
                     /locus_tag="NOB74_002161"
     CDS             11923..12186
                     /locus_tag="NOB74_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HCI1221328.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12180..12530
                     /locus_tag="NOB74_002162"
     CDS             12180..12530
                     /locus_tag="NOB74_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI1221329.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12554..13168)
                     /locus_tag="NOB74_002163"
     CDS             complement(12554..13168)
                     /locus_tag="NOB74_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1221330.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13482..13904
                     /locus_tag="NOB74_002164"
     CDS             13482..13904
                     /locus_tag="NOB74_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221331.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13914..14117
                     /locus_tag="NOB74_002165"
     CDS             13914..14117
                     /locus_tag="NOB74_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221332.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14328..14912
                     /locus_tag="NOB74_002166"
     CDS             14328..14912
                     /locus_tag="NOB74_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1221333.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5566 a         2454 c         3066 g         4051 t
ORIGIN      
        1 gaacatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 actagtacga ttgcaaaatg aattaaacga acaaattgaa aagatgtttg aacaccaaaa
      121 aatgacgaac ggtcaaccaa tgaacgacaa gaggaatggc cgttcatggt ttaaccagca
      181 agaacgaatc gaaaataaag tccaaagtct gagagaagag atcaagcaac aagaagaata
      241 cgtggaaaag cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 actggatatg acgatcgata atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg gctttttcag ccgccacgat ccgaaaatac caacggaagt tggaaacatt
      421 agaacagctg aaagaaaaat cagaaaaagg aaaagaaaat atcctccctg aagtacaagc
      481 gatcattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 aggctatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctag
      661 accaactgat tctatgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tcgaattgat
      781 cgatcaactc aaaacattgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaggaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccaa tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaaggg ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actatacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgtgg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cgtcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 tgcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctttagaaac gccagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtaa ttttaaaagg
     2221 aaaaagttat ggaaaagaga tccaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg agacagtgtc agaagtggca aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg tgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg ttttaaaatg accgagaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagatt atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ccctaagcaa caatttaaag cagccactga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtggaa aatcttcatt ttgaaacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaat atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaaa gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagataaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctgaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtctcta tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagtcga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaaatcattt atgaagaagt cgcaaaagaa gaaaaggtca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaac tggtttccgc
     3541 tcacaaagta aatgcgtttt ttggccagca gctttctgtt aacgattcaa tagaagccat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagtttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg cgcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggact ggaacgatca attgaagcat gagatccagc aacaagaaat
     3841 cagaaagcaa aaacgtgcca tgttgtttca acaaggcaga caacaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaagccgtc acaagcgaaa gcttatgccg
     3961 atagcttctc taaagccact cgaaaagacg ggtattttga aatccaagat cgattgtttc
     4021 ctggtgaaac tgtgatcacg tatggttttg gtcatttagt cgaattagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagaacattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatcgctt
     4261 ggacgatcat tcaacaagta ggcgccgatc aaggaaaaac ctttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagac gcaaaagaga
     4381 cctatccaaa atttgaagaa gcacaagcac gtcagatcgc cgattggtta attgggatga
     4441 acggtagccc actgtatagt ttactcttgc agcaaaaagg cataccagga agcttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attgcaggaa aagattagaa
     4561 atttcaagaa agaaccttat tttgaaggaa aatccgaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggcat gattcgccaa gttgaaaccg
     4741 agaaaaaaag cgcggcaagt ccacgtcttt tttctctatc cagccttcag tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagaca ctttggaagc catgcaaggc ttgtatgaag
     4861 ggaaatatct aagctatccg cgaacggata ccccttacat tacggaaggg gaatatgcgt
     4921 atctgttgga tcacttagac gaatacaagc attttttgag ggctgaagaa atttcgactc
     4981 ctattcatac accgaatagt aggtacgtga acaacaagaa agtccaggaa cattacgcaa
     5041 tcattcctac aaaaacagtt atgacagaag cgacgtatga aagtctgaca cctttacaac
     5101 aagcgattta cgagcaagtt ttaaaaacga cagtggcgat gtttgcggaa aaatatacct
     5161 atgaagaaac aacgatcttg acgcaagtcc agcagcttca gttaaaggca atcggaaaag
     5221 taccgataga tctaggttgg aagaagttat ttggcaaaga gagcgacgga aaagagaagg
     5281 aagaagagcc gctacttcct aaagtgacaa aaggagaaat ggtgacggta gatctacaag
     5341 tccttgaaaa agaaaccaag ccaccacaac cttataccga aggtacgttg atcactgcga
     5401 tgaaaacagc tgggaaaacc gtggatagtg aagaagcgca atccatattg aaagaagtgg
     5461 aaggaatcgg tacagaagcg acacgggcga atattattga aaccttgaaa caaaaggaat
     5521 atatcaaggt agagaaaaat aagcttgtgg tgacgaataa aggggttttg ctttgccaag
     5581 ctgtggaaaa agagccgctg cttacgagtg ccgaaatgac cgccaaatgg gaaagctact
     5641 tgttaaagat tggagaacga aaaggaacac aaaccacttt tctagccaat atccaaaagt
     5701 ttgtctctca cttattggaa gtcgtcccag gacaaatcca atccattgat tttggatcga
     5761 cgttacaaga agtgaaagca gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt
     5821 gtccaaaatg ccaggaacaa gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg
     5881 aagcctgtga ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gcgacacagc
     5941 tgaaggagat tattcaaaat agccgaacaa gccaaccagt gaaagggtta aaaggtcaga
     6001 agggttcgtt tgaagcaacg attgttttaa aagaagactt cactacaggc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac ttcaagaaaa gaacacgacg cacgacaaaa taatggaggg
     6121 ttaatcttat gcgtaataca acacacaaac aacaagaaat cgaaaatcaa aaagccaaaa
     6181 ttcgttcaga acaagagaaa ttacgtgcca gtaaaagaag acttcagcaa ttaaagaacc
     6241 agcaacggat tcaaaaagaa atcgaattag atcgatagac attaaccttg ttacaaatac
     6301 actatcatga tatatttaat gtagtgtatt tgtaacaaaa ggggggaagt aaatgcaaga
     6361 gaaactgaaa gaattgttgg ctattcgcga tggaaattta tctatgaagg aagccagaaa
     6421 attaggaatc gcagcaacca ctgtacaaag attggtgaat caaggaaaat tgatcaaagt
     6481 tgatcgtggt tattatgtag aggatggtca tggaatagat gatttatttt ggcttcagca
     6541 acgtttttcc aggggaatct tctctcatga aacgacttta gatatttacc agctttctac
     6601 gaatatgccg aaattcattc acttaacttt tccccatgga tataacgttg atcgttcaat
     6661 tacaaaagag cagcagttac aatttcattt cgtgaagaaa gaagtttatg aactaggaaa
     6721 agtagaggga acttcctttc aaggaaatcc tattactatg tatgataaag agcgtacact
     6781 ttgtgatatt tggaatccga gatatgaaat tgaatatgaa atgaaattag aagcattaaa
     6841 agagtacatg gaagacccat tgagagatcc aagtaaatta agagattaca tgacaaaact
     6901 acatgtagaa aaagaaatga aataccacat gcaaagctta tattgatgga ggaaaaagat
     6961 gacaccgaca caatttgcag caaaaacaag aaatttagca aagaggacag gattaaatgc
     7021 acagttagta caacggcatt ttatgatgga tcgtttaatt gaacaaattt ctgaatctaa
     7081 gtataaaaat gatttcattt tgaaaggtgg ctttttatta ggatcaaaat atggaatcga
     7141 tagaaggacg acaattgata tcgacacgac atttagaaat agcaaattaa ctgaagaaaa
     7201 attgaagagt atttttaatg atttaactag gaaacccacg aaagaaggta ttgttttctc
     7261 tattcaagga atgaaggaaa caagagaagc cgatttttat cctggatttc aaattaaatt
     7321 ggtggctaat ttagagaaag tacgtgtgcc atttaaaatg gacgtgacaa caggagattc
     7381 tatttatcct gaagtagata cacactatca ccaattaatg tttgaagata aaaaggtgga
     7441 gattccagct tatccaacag cacaaattat tgcagaaaag ctaagtgcta cgttcagctt
     7501 tggcacagat aattcgagag caaaagatta ctacgactta tttaccattc cgaaactaga
     7561 aaatatcgat acgaaagagt tatacaaaag tgttcgaaat acatttacaa aacgtgggga
     7621 tacaaaaccg ttgtcctttt attatgaaag agaaatggat aagatcatag gaaatgacta
     7681 tttggaaaag cagtgggaaa aatatcgctc agttaacacg tttgcgaatt ccatttcatt
     7741 tacagataca gtcaacgaaa ttgatcacct aatgaaaagt gtgatcaaaa ttgaaaatca
     7801 agaaagaaaa cggcagttta aaagatcaca acaaatgaat caagaaatgg agagataaag
     7861 atgatcaata atgtaacttt agtaggacgc ttaaccaaag atccagattt acgttatacc
     7921 gcgagtggta ctgcagtagc gacttttacc ctagctgtca accgaaattt cacgaatcaa
     7981 aacggcaatc gagaagctga ttttattaac tgtgtgattt ggcgcaaacc agcagaaaca
     8041 atggtgacat tagctaaaaa aggtagcttg attggtgtag ttgggcggat tcaaacgcgg
     8101 acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc cgataatttc
     8161 caactattag aaagcaaagc agcgacagaa agccgtgcgc acgctgatca atcgtccacc
     8221 agtccaagca ccaccacttt tgaacaacgg gatacagcga cgcctaataa caatggattg
     8281 aacgctttac agaatccatt tgggaatcca tttggtggac aatcaatcga tattagcgat
     8341 gatgatctac cgttctaagt agcattttct attggttgca tttgctacgg tttatgttat
     8401 aatttagtca acaaaaagaa ttttcaatct ataaccaaaa accactagct ggcgggctag
     8461 tggttttctt ttacgtttct attataagaa ttaacgggta ggcttactgt ctttcttggc
     8521 aaatttacaa tcaagccatt tgcagatata gtgcgcggct acttctgcca tgattgcaaa
     8581 aacaaaatca aaaagaattt tcaaacctat aacctcctcc ccttgccaga ttaggccggg
     8641 gtagcagaca gcaagactat tatagcataa ttgaaatatc caaatgattg gatttttgct
     8701 ataattttag cgaggtgatt gtgatgaaca aatatgttgg tttgcttgat aaaatccgag
     8761 taataaaaac gcaaccgtta ttggttcgct ttactttaca aacgattcat gaatcgatta
     8821 attgtgtagt tgcagatatt gaaattatcg ataaattgct aattatggat gatggaaaat
     8881 acaatattgc cgtcacaggt cacttcaata aacgaaatca gctagttatt gctagcatgt
     8941 atgttagaaa tcccgatcat tttacgcgat cgatgggcat ataaaaaaag aagagttgca
     9001 atcctaatgt aggactgcag ctctttttgt tttacataga aacaagaaaa atgaaaaggc
     9061 ctttttagga aggcgcgagc gccttctcaa ttgaaaaacc tctctcactc caaccgccac
     9121 cgccgttcga gaagaaagga agtgaacgct acgcgttcac taagataaag ggtcttgcat
     9181 agcaagacaa aatagaaaaa acttcctctc accaaaaggt tcgctcctgt tcgttatctc
     9241 tttattgatt tgtcagaccg tcaacaagtt gccttttatc accaaaaagc gacaaggaca
     9301 agggtaaatg gcacgctgca cgcccttgtc cttgtcgctt ttagttgatt cattctggcc
     9361 aacaaatcaa taaagaaaga actaacgaaa ggaagtaaaa cctttcctaa gaggaggcag
     9421 aatcaatcat gcgaaagaaa tttgattatt ggggtgttcc cttcagcgaa ttattcccaa
     9481 actatcatgc accatatact gtcgaatgcg attgtggaga aagagcgaaa tgtatcaaaa
     9541 gctattgttt gtatcaatgt ccaacatgcg ggaaaaaata taccttgtct tatggcgatt
     9601 atattttgat tgatgagaaa ggaaagaaac gctgatgaaa acacaacaca aattattgac
     9661 tgtaaaagaa gtcgttcaaa ttttggtgga caaagaagtc atttctgaaa aagtagcaga
     9721 agctttactt attccgcggt actggacgat agaaacccct ttagtagagg atgcaccgac
     9781 tatgctattt gaagacctag tgaagattgc aggatatgaa ctgcattatc aagaaaacat
     9841 ggaaacttat gaaaacgaat attggttaac caaattagag aactaaaaag gagaaaaaaa
     9901 tatggctcaa aattactatg acgaatttgt caaattacct ttggataaaa tggcacaaaa
     9961 aatggaggat atgacattcc tatacaatga gacacgtgta ccaaaaaaac attataagga
    10021 aagattgtcg gtagctgtgg aagaaatgat tgaatcgggt gtcgaaatga atctcattgc
    10081 gacctactat cgaacgcttg aagaactgaa aaagcaaaat ggacaatggt ttttccaagc
    10141 cttactatgc ttggaagcag gcgtcaagcc aaacactatc aaaccttctg aataccaagc
    10201 tttagaacta acgtatggga aatttgtcga aacgaaaaaa gccaagactg tttcaagtga
    10261 atggttggac tacttagaaa atgtcaacaa gtatggcgca tgttacatca tgaaaaagga
    10321 ggacaacgaa aatgaataag gtgatttatc aactaacaac ggaagatgtg tcacactttt
    10381 taacaaacaa agaacatttg aatgaagtaa tcagacggat tcaaaaagac tttagttgta
    10441 tggaagaaat gaagtacttt attcaaagag tcgaagaaca attgtatttg gaaagtgaaa
    10501 cgagtcaaac gaaggtcaca gtcagcaata attatttaga cgtgtataaa catcgtcctg
    10561 aaacggtaaa aaaaggaacg gagcttctac gactagaaac agaaaaatac atcatgaatg
    10621 tttacctaga aaggagtgaa ctggtcgaaa actttgtcag ctgcacgatt tgcaggaaac
    10681 actattactc agaatcagaa tattattcaa tttttgagag catggaatta atggaagaag
    10741 aaatggaaga gctaaacagc aaaaatgcga cgatagacga ttattatctt gtatttacta
    10801 gatttttgac gtgtggaacg gaatctatcg tgttaatggg aatggattat gaactcgctg
    10861 tacccgaagc atttttgagg gaatatgtag aagaagtaga taacccaggc gacgactggt
    10921 acacgacttt aactgatttt ttagatacct acacttacga cgatacagaa gaaatccaaa
    10981 atgaacttga ccgtaaacga atgccatatc aacgatttga aaggaaaaaa aggcaataat
    11041 catttatacc gaaaagtgag aatgtgtgaa ataagaacaa aaaccttgaa attaagggaa
    11101 tggttcttat ttcgcaccaa tcgctccaac cgcccccgcc gcttaggtgg tgcgaaataa
    11161 gcgggcaaag cccgataacc taagagaaag aaggagatcc atatgaataa aatcattcct
    11221 ctgttgttcg tactgtgtat tggcgagata cttatgcgtc atggtgcagc tgtacattta
    11281 aacttcgtag tattcttagg aatactagta ttttgtttga ttttttggcg ctttgtgtta
    11341 gcccttgtga gtctactatt caagttgatt gcagccatat ttttcatagg gttatttcga
    11401 tgaaaggaga gagtactaat gccaattgca ataggaaata aacggttacc cgtgacatta
    11461 gatgaaaaga gacaaaaaga attgcagcaa ctaaagcaga agtacggaaa aagtgaatct
    11521 aagattatgt gtattgcgtt agatctattg atcgcgcaag aaaaagcagg atttgatata
    11581 ccagcactaa aaaagtgacg tcacttttca tttgaagaaa caaaagtgat agcacttaat
    11641 tgttcctact atttagaata ttttctatgt cctttttatt ccattttgta tcaataacta
    11701 tgaaatcttt aaagtatcca gatcaatttt tttcttacct gattctaaag attttgtttt
    11761 cttaaacata ttatgatttc ctttcgacta ttttcatata aatgttaaca tagtttatgg
    11821 attcatggaa tgttaatcta atttaataga aaaggataat taagtatata cgttttttct
    11881 tatgtatgtt atactatgta tatacagaaa gaggtgtcta ctatggaaat gttacctata
    11941 aaaaaatggg gaaatagtaa tggccttaga ttgccaaagt atattatgga atatcttgga
    12001 attcatacag aagacaaagt gaagataata caagaagaag taaacggtca gaagcggcta
    12061 attatcgaag cggctaatat agaaaatgaa ttaacaattg aacagttatt tgaaaattac
    12121 actgatgaaa gaaatcatgt gacgattcaa aatttaggtg aagcagtagg taatgaaaaa
    12181 tggtgagaaa acctagacaa ggcgatattc tattattgaa tacagcacct cgatctggac
    12241 acgaacagac aggtaaaaga ccttatattg ttttaagtca tgatattatt gcggattata
    12301 gtaacgttgt tacagttgct ccaatttcta gtacaactag aaactatccg ctatatgtaa
    12361 atataaactc agaatatgaa atgaagacaa caggaaaagt attattagat caactaacga
    12421 caattgatta tgaagccaga gagtgtattt ttttggaaaa agcgcatgat agtttagttg
    12481 aggagttatt gatgaaagtt agaacagttt ttcaaaaagt aagcaaataa aatagaaaca
    12541 gcagcatgat caactattcg tgattgacca tgctgtcttt ttttattcta tatacggttt
    12601 gtctcgtaac attgtagtct tttgcaatct tagcgatcgc aacacctttt tttagatcct
    12661 caacgatgtt tttataaaca agacgacgtt ggggatcttt tgcattggca ctgtatagct
    12721 taggacgtcc tttataaaca ccgttcgctt ttgcaatctt aatgccttgt gcctgacgtc
    12781 gtttagattc ggtacgttct tgttcagcga tcatggccaa aatttgaatg atcaaatctt
    12841 taatgaattt atccaggaga ggattgccaa ttgcttcggc catgatcggt agacttgtga
    12901 tgatcagctg cacatttttc ttcttcaagt aattgactga agcgatgatc tcgtcgtaat
    12961 ttcttccaag tcgatcaata gcttccacaa taaaaatatc ttgatctcgg acgaaatcca
    13021 gtgcttcttg aaaaacaggt cgatgagtaa tcgttgcgcc agattgtttc tcaatgaaaa
    13081 ttctctctgc accgaatttt ttcatttctt caatctgccg ttgttcattt tgatcgatgg
    13141 atgagacacg tatgtatgca actctcaaaa tttttaccta ctttctgcaa ctatttaaaa
    13201 aacaccctaa tcatacacga gaaaaccaga tttttcaatg tcgcggtcgt gtctagttag
    13261 ggtatacctt atatagacaa aaactaatga tggaggaaat agtatgtgtc acttttcttt
    13321 ttaaatggca atattttttg taaataaatg tcaatcaaga aaatttaaac gattatgaca
    13381 ttaaaaatat attttatgaa ttttctagta tataacttga tttatctgtt aagatttatt
    13441 aagaaaacgt tttcttattt ttgatttcga ggtgatagac aatgaaaaat aagtttattt
    13501 tatctttagg tattttaact attggaatta gtgtaactgg aactacaatt cctacatttg
    13561 ctgatagtac aaatgaacca actactgtag tagataataa ccaagaatta actcctttag
    13621 ataggaacgg aatagccatt ggtaacccaa ctaacgactt aactgttact gaaaattatt
    13681 taatagtttc tccattactt gctcgagcag cttctaaaac gatacgagtg acaggaacga
    13741 tgatttttga taaagttggt tggccttcta gacctcctca atcacggaat tggaaagaaa
    13801 aaagaaatgg ttattggtac tatggaaaat tgtatttaca aagttataaa tcagctggaa
    13861 acaattggat tgcgacttat tcaggaacct taactagaaa gtagggattt tttatgccag
    13921 aatttgtgaa cacaccaaat ttttatcaag atagcgatat tctaagtaaa attaatttac
    13981 cgaaagaaga atcagcttta caagttcagc gaactttaca ggagacacaa aaaattcaaa
    14041 aatcaatttc taatctagaa gattctgaag aaaaaagaaa aaaaagagac caaaaaacat
    14101 atcaaaaaga aaaataatga ttttaaaaaa agagtgtcta gtcgacattc tttttttcta
    14161 attgaaagtg ttcataaaat cacccatttc tggacacttt ctttttttgc tttatttttc
    14221 aaaaaaacaa ttcatttcat gttcataaac ccataacaat atctatgttc agttaaacta
    14281 tatggataaa gttatgttac aataaaatta atgaaggagt gatttttttg aaaataggat
    14341 acgcccgggt atctactggt ttacaaaatt tggatttaca agaagacagc ctaaataaat
    14401 ttggttgtga aaaaattttt actgatcata tgagtggggc aaaaagtaat cgaccaggat
    14461 tagaaatggc cattgatttt gttcgctctg gcgatacact tgtcgtttgg cgcttagatc
    14521 gtttaggtag aaatatggaa gatttgattt caatcgtcaa tcgactgaat gagcgtggtg
    14581 tgagttttca tagtattcaa gaaaatatta cgatggacaa atcaagttct acaggacagc
    14641 tcatgtttca tttgtttgcg gcatttgcag aatttgagcg taatttgatc ctggaacgat
    14701 ccgcagcagg acgagcagct gctcgtgcaa gaggacggtt tggtggtcgt cctgaaaaat
    14761 tgtctgaaca agatttggaa ttactgaaga ctttagtgga tagcggtaca cctattaaga
    14821 ctattgcgga acggtggaac gtctcaagaa ccaccattta tcgttatttg gcaaaaatgg
    14881 aggagaaaaa tggaaagaca aattctcatt agtttttgtc atttaatgct gaaaattttt
    14941 gccatttatc tagaaaagtg acaatagtat gagaattttt tgtaagtgtc tactgataac
    15001 ttattctcaa atgttgtaag gattttattc atttgttaat attaaagaac ggaactccaa
    15061 aaaagtccgt actctaattt gcagtctctc actcttttag agtgagagtt tttattagat
    15121 tttcaaatta attagta
//
LOCUS       DAIGWC010000066        14993 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.067, whole genome shotgun sequence.
ACCESSION   DAIGWC010000066 DAIGWC010000000
VERSION     DAIGWC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.067"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..607
                     /locus_tag="NOB74_002167"
     CDS             <1..607
                     /locus_tag="NOB74_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221334.1"
                     /translation="ENQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDT
                     PVVYHDAPPFAPATKIVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYD
                     QRETKSPWILTIKLSQPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQ
                     TDYSEYLNNGRAFKLVLTKENQIAGNYSAEMTWTLADAPTE"
     gene            627..1655
                     /locus_tag="NOB74_002168"
     CDS             627..1655
                     /locus_tag="NOB74_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI1221335.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1652..2410
                     /locus_tag="NOB74_002169"
     CDS             1652..2410
                     /locus_tag="NOB74_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI1221336.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2496..3236)
                     /locus_tag="NOB74_002170"
     CDS             complement(2496..3236)
                     /locus_tag="NOB74_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1221337.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3297..4550
                     /locus_tag="NOB74_002171"
     CDS             3297..4550
                     /locus_tag="NOB74_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI1221338.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            4851..5099
                     /locus_tag="NOB74_002172"
                     /pseudo
     CDS             4851..5099
                     /locus_tag="NOB74_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5221..5547
                     /locus_tag="NOB74_002173"
     CDS             5221..5547
                     /locus_tag="NOB74_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCI1221339.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            5615..6328
                     /locus_tag="NOB74_002174"
     CDS             5615..6328
                     /locus_tag="NOB74_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCI1221340.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            6638..7490
                     /locus_tag="NOB74_002175"
                     /pseudo
     CDS             6638..7490
                     /locus_tag="NOB74_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            7611..9476
                     /locus_tag="NOB74_002176"
     CDS             7611..9476
                     /locus_tag="NOB74_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1221341.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            9524..10933
                     /locus_tag="NOB74_002177"
     CDS             9524..10933
                     /locus_tag="NOB74_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HCI1221342.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            11041..11742
                     /locus_tag="NOB74_002178"
     CDS             11041..11742
                     /locus_tag="NOB74_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1221343.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            11901..12380
                     /locus_tag="NOB74_002179"
                     /pseudo
     CDS             11901..12380
                     /locus_tag="NOB74_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            13228..13803
                     /locus_tag="NOB74_002180"
     CDS             13228..13803
                     /locus_tag="NOB74_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HCI1221344.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            13803..14243
                     /locus_tag="NOB74_002181"
     CDS             13803..14243
                     /locus_tag="NOB74_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCI1221345.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            14259..14960
                     /locus_tag="NOB74_002182"
     CDS             14259..14960
                     /locus_tag="NOB74_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI1221346.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         5066 a         2484 c         3161 g         4282 t
ORIGIN      
        1 agaaaatcaa ctttttgcag gagatgtatt agaaattgta ttaaacgacc aagcaggaga
       61 agctgctgct aagggtgtgc agaacaagcc aagtaccaac gatgaaattg ggaatcacaa
      121 tccaagtgat acgccagttg tttatcatga tgccccgcct tttgcacctg ctacgaagat
      181 tgtagtagaa ggtggtctct catttcttgc cccttccaaa ctcgattgtg gtcagatcaa
      241 agcaactggg ttgacgcaag aagcatttgg ccaaatggat atacaggaaa aattatggat
      301 ttatgatcag cgagaaacaa aaagtccatg gatcttaacg ataaaattat ctcagccttt
      361 cacaaccgat gcaggatttt ctatgcagga tgtcctatat ttcaagaaag ctgaggagta
      421 tcaattagtg aatgaagaag aactggaaat tgtcagagga caaaattcaa cgaatgtgca
      481 aacagattat tcagaatatt taaataatgg tcgggcgttt aaacttgtct taaccaaaga
      541 aaatcagata gctggtaatt actcagcaga gatgacatgg acattagcag atgcgccgac
      601 agaataaaga tcaaggagaa tgattgatga atcgaatatg gaataaaagt catcgaaaca
      661 actgctcttt acttctgatc cttctccttg gattcatcct ttggcagaca cctgtccatg
      721 cctccgaatt caattttgcg gtagattttg aattaccggc taatcagatt gataagaaca
      781 aaacatatat aaatgtaagg atggagcctg ggaaaacaca ggaaatcccc tacacggtct
      841 ttaaccgaac agataaatca gtaacagttg agacattgat ccactccgct acgacgaatt
      901 caaacggtgt gatcgaatat ggagaatcaa aaagtaaatt tgatgaaaca ttaagttatg
      961 atatgaaaaa cttagcaaaa acagtgggag aaataactgt ccctcctcaa agtgcggtca
     1021 ctgagacact ttcactgaaa gctccagaaa aagagctggc tggtgtggtc gcaggaggaa
     1081 tcacgtttca agaaaaaaaa gagaacgttt ctaacaaaag tacagttggt gtcgtcaatc
     1141 agttttctca agtgaaagca atcttgattc gaaatagcga aaaagagtct tccccaaatt
     1201 tgaaattaaa aaaaacttat gcggatcaaa gcgatggaag aaatgtgatt aaggcgaatc
     1261 ttcaaaatcc aaatgcttct tatatgttcg gcttgactac atcggttgaa atctacaaaa
     1321 aagaaacaaa agagccttat ctttcaataa aaaaagaaaa aatagatgta gcacccaata
     1381 caaattttga tttacttgtc ccattagaag gaaaaaaatt agctccggga cattatcaag
     1441 cggttgtgaa gggtgcttgg aaagaaaaac gctggaatct ccataccgat tttgaaataa
     1501 ctgatgatgc agcggaccaa ttgaatgaaa aggatattga tttaaaaaat cagccagaaa
     1561 catttgactg gcgatggctg atacttgttg gagtcattct tattggctta tttgctggat
     1621 tatttatttt aaaagaaaga aggaaaaaga aatgaaaaaa acaattgcat taagtaccgt
     1681 tctagctgga agtctattat tatgtacaca aagtgttttt gctgagaata agagctcagc
     1741 cactacagaa ggaacgattt ctgtaacaaa accagatgcc gcaaatcctg aagacgttgt
     1801 tccagttcct cctgttgatc caaatgatcc cgatacgccg tttacaccta acgaaccaaa
     1861 tcagggaaca tccggattac tgacgattga ccaagctcca gatcttgatt ttggaacaat
     1921 caagttaggt acagcaaaaa cagtatatgc tgcattacaa aacggaacgg acagtacagg
     1981 gacagcaaca caagtacaga atttcgtaca agtaacggat aaaagcggaa tttatgccgg
     2041 ttggaaacta tcagtcaaac gaacagaatt tattggtaca acatctgata cgaataaact
     2101 aactggttca aaggtgaaat tcaaaaacgc cgtgattcga aatagcgcaa ctaatagcag
     2161 tggaacgcca tctactattt ctggtactgg cgctgaagga attgagatcc cagcagatca
     2221 ggcagtagat ctagtaactg caggagcaaa tgaagggatt ggcacatgga tttattcatt
     2281 aggagagaat gtggaacaag ggagacaatc agtggaatta tttgttcctg tatccaatta
     2341 tgccgtagac aactacgttt caacattcac atggtcgtta acagatgctc ctacagaagg
     2401 gaaagcgtaa aatcaaatca atgacttcag ggagtggagc cgattcaagg ccaactccct
     2461 gaaatctgct atgcttacgt ctcagctctt attcatcaac tcgaagcagt tttttggaag
     2521 tcatggaaac gttcctttgt cttttcaaag atctttcgac caacgagtaa ggagtcacca
     2581 ttgaaaaatt ctaacacata atgagcagaa tcaattttct gcaattgcga taagttgata
     2641 cagtaagatt ttaatagtaa aaagtaagca tacttttcca actctgtctt caattgtttt
     2701 aaagaagtat tcactaattt atcttctgta gttgttttga ccataacttg gtttttcaaa
     2761 cctttgatac tttcaatata taaaatttcc cgaggataca ggacgagact tccacctttt
     2821 tgatcaataa agattttatc gacatttacg atttgctgtt ctttccaatt gatctgttct
     2881 agcacttgac gaatttgttc agataaattc ctgtcttttc tgatatatcc aatcggaagg
     2941 attttccgat tgatgatctc tactgcaaaa ttcgtataag cggtgaaaaa aacaatatta
     3001 ctatgtgcat tttttttacg tatttgttcg gcgacatcaa tacctgtgag tgattgcttc
     3061 aagtcgatat cgataaagaa aacatcgtga ttatcaatag tacccaactg gatcaactga
     3121 ttgatttgag agatagaagt gagctgcacg atattctcga tatgatgatt gaccaattct
     3181 ttgatgatcc attcgctgtg aaactggtta tcttctatga taaaatactt tttcatatgc
     3241 aggctcctat taaaaaaata tgtgtacatt ttgaaacaaa acaatggagg aataagatgg
     3301 tcgcaacagt gacactttat ttgaccttta ctttgatttt agatttaggt atctatttat
     3361 tcttttcgaa acaactgcta gtaaaaaaca gctttggttt tatagctttg atggtggtga
     3421 cacttttatt tcctatccct aaagtgagct ttccttacct agttggctta ttattgatgt
     3481 ttctttttta ttttactacg aaaaacctgt ttatcagctg tttgatcagt aatctttttt
     3541 ttgctatcac tggactcagc ttttttctgg tttttgatct gatggattat ttaggaaaga
     3601 gacatcttgg aacagcaagt ttttttgcac tacttatcgc atttattttc tatctattag
     3661 taaaaagtat agacaaacag acgagatttc tcaacttgct ttttacttat ccaactgaac
     3721 actattttgg aggtatttgt attttattaa gctggggcgt gatttacttg gtattgggaa
     3781 gtgttcactt ccgctcatct aattatctgc ttctatctct tttgtcgata gtcatcagtt
     3841 ttttttcttt gtttttttcc attatgttga tcagtttcca agtaaaagaa agacaacatc
     3901 aggaatcgct tcaactgtat caaataaatg aagaatatta ccatcatcta gaggaattca
     3961 aacatgatta taaaagtcta ctgttttcat taaaaattac tcttcaggaa aataaaaaag
     4021 aaacgttgga atttttagaa atcttagaag atcattctgc agctattttt gaaaaaccgc
     4081 aaatacaaca gctaacaaat attgtatccc cagctgtcag gggtgtcttt ttaaaatttc
     4141 tagaaaaagc agaatcggag aaaatcccga tccaagtagt tattcctgtc gaagtgaaaa
     4201 caatcccgat tgatctggtt gtttttattc gctgtttatc tatttttatt tctaacgcat
     4261 tcgatcatcg tgtagccgat cagagtccga ttacgatcaa tctgctggaa gaaaaagagg
     4321 gattacgttt tagtatagcg aacaaggcaa atccgacgaa tttgacgcta tcggagatgg
     4381 tcaaaagagg aaaaacctct aaaaaaaatg gcgggttagg tctatacagt gcgaaaaaaa
     4441 tgttggatgt ttacgaaaat gcagaactaa aaatcgaatt ttcaaaacag aatcactatt
     4501 tttttgtaga aatgtatctg gcatctagaa agagcaaatc agcctactga cttactgtca
     4561 aaggataagc ttgaggaaag tctacacgga gatagagaca acaacacagc atattcaaaa
     4621 gaaacagaag cgtgatgacc gttgtcaccc ttctgtttct tttgctatgt agttaaacaa
     4681 agtagttgac acttccgcta cttagtatta gtacgaaagt atacttcatg atactaagta
     4741 gataagaagt gaaaagcgga acccacgatc gtcaaaatgc taactgcttt gcttacacca
     4801 gataaaggga agagcaatat cgcttatttt aggcgtggag aagcaagaaa atccctacga
     4861 tcacacaaaa aatgctgacc cagcagttaa gagagttaga acaagatggc attgtccatc
     4921 gaaaagtcta taaccaagtc ccgcctaaag tagagtactc gctcaccgaa gaaggaaaat
     4981 cattaagaga gattctagta gcgatgtctg tttggggaga agaacgtatc gaaaaacaaa
     5041 aagcctcagg ggaagaagtc acattactgc atacacatgg tggctaccta aattactgat
     5101 ttctatgaca tttattttaa ataaaagaaa acaggagttt ttttaaaagc atcatctatt
     5161 ttttatgtaa aaaaatggta tgattaatca agtaagaaat gattggaaga aggcaagcaa
     5221 atgaatagca tggaaaaagt taaccagttt agagatgaac gtaattggcg acaatttcat
     5281 aacgaaaaag atttggctat ttctatttct ttggaagcat ctgaattgtt agaacttttt
     5341 caatggaaaa cgccggaaga agtaaaagaa acacaattag aacgaatcaa agaagaactg
     5401 gcggatgtat tgatctattc atacatgatg gcagacaacc ttcagctgga tctagatgag
     5461 atcattgaag aaaaattgat caaaaataat ttgaaatatc ctgtagaaaa aagcgcaggt
     5521 gtacgaaaaa aatacacaga gttttagaaa tgtgtcattc ggctgttgga aagagcaaaa
     5581 gaaaaacagt aaaatgagtc tggagggaga gaaaatgaaa aaaaaaggaa aagcaaaaag
     5641 atggctagtc aatatcctct tgttcctctt gttattagta ggactagctt tgattttcaa
     5701 tgaacagatc aaggattatc ttgtcagaga gacaggagat aaatatgcta tagcgaatgt
     5761 aacaaaagaa gatctgaaaa agaataacga taaagatgtc agttttgact ttgatgcggt
     5821 agaaccaatg acgacagaag gggtcatgag gtcgcagatg agaggaacag atctaccagt
     5881 gattgctagt atcgcagtcc cttcagtttc aatcaattta ccgattttca aaggcttgga
     5941 taatacgtca ctactttacg gagcaggaac attatctcca gatcaagaaa tgggaaaagg
     6001 aaattatgcc ttagcaagcc atcgtgcaac gaaccctgaa ttgttgttta caccgctgga
     6061 aaatttagag atgggtgcca agatctattt gacagattta gaaaatgtgt atacatacaa
     6121 aacatttttt aaagaaaaag ttgctcctac agatacccaa ttactgaatg aagtcgagga
     6181 aaaagaaatt gtcacactaa ttacttgtgg cgacatggac gccgtcacgc gactagttgt
     6241 acaaggagaa ctggaaagtg ttacaccgat aaaagatgcg acagatgata tgagatctgc
     6301 tttcaatcta gagacaaaaa cattttagga tactgggaca taagtcgtta cagattaaaa
     6361 acagccaaag gatatgaatc gataaggaaa aaccaatttg ctgaaaaaaa gaggaacgca
     6421 aagaggtgca tctctgattt ggttgttttc tagatagact tgtgttccag tttttttatt
     6481 ttttatatga aaaggcttgc ataaataaaa attcgatggt atgatgattt tgaataagaa
     6541 atggattgtt actgtacggc aggcaaaacc agaattcagc taagaaacag taggcgaatt
     6601 ctaggttttt ttatttttct tgagagggcg aagcaaaatg aaaattgata aaattttgaa
     6661 taacaatgtc gtcatttcga aaaatggatt cggggaagaa gtcgtttgta tgggaaaagg
     6721 actagctttt caaaaaaaag attggggacg agatttcgcc agaagcggtc caaaaagaat
     6781 ttattttaag agattctttt gctaaaaacc aattccagca gctgatggct gatattccgg
     6841 cagaggagat cgaatgggtc aaacaagtag tcgaactggc tgaagataaa ctaaaagttg
     6901 aattttcgcc taatatttat ctgacattga ccgatcatct tcattatgcg atcacacgag
     6961 caaaagaaaa tatccaactg cctaatccat tattatttga aacaaaaaaa ttttatccga
     7021 aagaatatca agcagcgaaa gaggctcttt tgttcgtgaa acaaaagacg ggtgtggaac
     7081 tttctgagga tgaagccggt tttattgcct ttcattttgt gaatagccaa caaggaaacg
     7141 aagacatgca agtgacgatg accgctacca caatggtaag agatatactg agtatcatca
     7201 gtaaattctt cggcatcgtg ttcgatgaag aatctttgaa ttatcagcgt atcattactc
     7261 atctgcagtt ttttgcccag cgttatctca aaggggaagg atctgacgag caagatgaat
     7321 ttctctacgc attagttcaa ggaaagtatc caaaagcgtt tcattgtgtc gaacggatca
     7381 atgagtatct tcgacaaacg caaaaacagg aaatggggat cgcagagcag atttatttaa
     7441 cgattcatat tcaaagagta gtaagtgaga aaaaaagcat ccaatcataa ggattgttac
     7501 tgtatggcag gcaaaacctg gattgaaaaa ataggttcac gaatgtttgt gactgttttt
     7561 ttcaatctgg gtttttattt tttaaataaa aaagaaagaa ggaaaaaaca atggataatc
     7621 aagcagttgg tcgtcgtgta tgggaagcgg taggaggaca aaagaatgtc aaaagtttag
     7681 tacattgtgc tacgcggttg cgattcagat taaaagatga atctttagca gatacgcaaa
     7741 agttaaaaga agacccggac gtgatccaag tcgtacaaag tggcggtcag tatcaagtag
     7801 tgattggcag taatgtagca gatgtttatc aatcgatcgt ggatgaggaa ggtcttgcag
     7861 tttcggagga tggaaaagaa gagtccaaaa atattttgaa tcgtctgatc gatattatct
     7921 ctagtatatt tacacctttt ctaggggcga tggcagccgc cggggtattg aaaggattct
     7981 tatcattggc aacggtgatg ggctggctga cagctgatag cggtacttat caaatattgt
     8041 ttgctgcagc agatggtgtc tttaccttct tacctgtcat gcttgctttt acagcagcta
     8101 aaaagttcaa agccaaccag tttttagcag tagcaattgc tatggcactt gtgtatccag
     8161 ctatcacagc agttgctggt gcgggagaag ctatcagttt ctttgggatc ccagtgattc
     8221 tttcaccatc tggttatact tcttctgtca taccaatcat tctagccgta tgggttcaaa
     8281 gtaaattaga gccattcgta aaaaaagtga ttccgcaatt tctgcaaatg attttagttc
     8341 cgcttgtcgt tttagtagtg atggttccat taacatttct tgctttagga ccaatcggga
     8401 cggttgccgg taatgcttta ggcggtctct tcaactcgat ttatggattt agtccaatcg
     8461 tagcaggtct aatcatggga agtttatggc aagtattcgt gatgttcggc atgcattggg
     8521 gattcgtacc gatcatgttt ttgaatatcg aacaatatgg gtttgatgta ttgatgccaa
     8581 tgcttcttcc agccatcttg gcacaaggtg gggctgcttt agctgtagca ttgcgaacaa
     8641 aagatacgaa acttcgagca ttagggattt cttctacagt gacttcgtta tttggaatca
     8701 ctgaaccaac tgtgtatggt gtgacattac ctttgaagaa accattcatt gccgcttgta
     8761 tttctggagg tattggtgga gctattatcg gattttccgg agtaaaagct ttctccagca
     8821 gtttggtcag cttattgacg attccgactt tcattaatac ggtggatggt gtagagtcaa
     8881 atgtgacagt agcagtaata gctacaggaa ttgcttttgt tcttgcattc gtaggtacat
     8941 tgattttagg atttgacgaa caaacacaag acaatcaatt agaaaacaaa catgcgaatg
     9001 caggagaacc gattacttca gcacggcata ccttaaaaag tcctttaacg ggtaaagtac
     9061 tgccattgag tgaagtacca gaccaagttt tttcttctgg cgtgatggga aaaggtatcg
     9121 ctattgatcc agaagtagga gaactagttg cacctgcaga cggagagatc acgactattt
     9181 ttccaactgg acatgctgta gggatcacaa cgactgacgg agcggagatt ttgattcata
     9241 tcgggatgga tacagtagaa ttaaatggga atggctttga gatcttagtc aaacaagggg
     9301 atctcgtcaa agcaggagat ttattgattc gttttgacat cgaagcaatt agagcagctg
     9361 gctatagcgt aatcactcca gttgtcatta cgaatactga tgcatttgcc gatatacttg
     9421 aattagacca aaaagagatt attgcaaacg aagatgttct ggcaattgta aaataaggag
     9481 gaaatcagga tgcaatcacg tttttcagaa aaatttttat ggggtggagc aactgctgcc
     9541 aaatcaatta gaaggggctt atgatcgaga cggaaaagga ctatccgttg cagatgctat
     9601 gcctggaggt aagcagcgct ttgcgattat cggcagtgaa gaatttgact ggacgattga
     9661 tcaagaaaaa tatatttacc cgaatcatcg aggaatcgat cattacgatc gtttcaaaga
     9721 agatcttgcc ttgtttgcgg aaatgggatt caaatgttat cgtttttcga ttgcctggac
     9781 acgaattttt ccaaatggag acgaaggtac tcctaacgaa gcgggattag aattttatga
     9841 tcagctgatt gatgagtgct taaaatatga tattgaacct gtgatcacga tttctcatta
     9901 cgaaatgcct cttcatttgg caaaagaata cggtggctgg aaaaatcgaa aactgatcga
     9961 cttctatgaa cgatttgctc agacagtatt agagagatac agcagtaaag tcaaatattg
    10021 gatgactttc aatgaaatca attcggcctt tcactttcca gctttaagtc aaggattagt
    10081 aaaaagcaat ggagcaggag agtaccaaaa tattttccaa gcatggcata atcaattcgt
    10141 tgcaagtagc aaagccgtaa aaatcggcca cgaattgcgt tcggatatcc aaatcggctg
    10201 catgattatc tatgcaacaa cttacagcat cgatgccaat ccagtcaatc aggcagcaac
    10261 aatgatccaa aaccaagaat tcaatttttt ctgcacggat gtccaagtac gtggagaata
    10321 ccctgcatac acagcgcgta cccataaaaa atatggagtc gatccggaaa aattagagca
    10381 aacggaaaaa gacttccagt tgctaaaaga atatccagtg gactacatcg gatttagtta
    10441 ttatatgtct acggcaatca atgagactga tccacaagca gcaacttcag aagggaactt
    10501 gctgggagga gtaaaaaatc cgtttcttga ggcaagtgaa tggggctggc agatcgatcc
    10561 agaagggctg agaatcgcat tgaatgaatt atacaatcgt taccagaaac cattattcat
    10621 tgttgaaaac ggtcttggag ccattgatca tatggaagag gatggcacga ttattgatga
    10681 ttatcggatc gattatttac gtcgtcatat cgaagcgatg gctaatgcag tagcagacgg
    10741 tgtagatttg atgggctata cgccttgggg atgtatcgat cttgtcagtg catcaacagg
    10801 agaaatgagt aaacgttacg gctttatcta tgtggatcta gacgatgaag gaaatgggac
    10861 actgaatcga tcaaagaaaa aatcttttga ttggtataaa gaagtaattg cctcaaatgg
    10921 cgtaaacttg taattaaagc agctgaatga aaaagaacac acttctcaca tgtgatttgt
    10981 gttctttttt tattttttat gtgctattct tttagtaata gtaaagcaaa gggtgacgtt
    11041 atgaaaagga cacgtgtact atacttggaa gtcgcagata aaattaaaga agatattttc
    11101 tcaggaaaat atccagtcgg ttcgatgttg ccgacagaaa gtgaattaga agaactgttt
    11161 caagtcagca aaatcactgt ccgaaaggca atcgaactgc tggcatcaga tgaatatgtc
    11221 gcaaagaaaa gtggtcgtgg gacgacggtt ctaagcaatc gtccttacaa tcgattatcc
    11281 aaagcggcaa gctttacgca aatcttggag aactcccgat atgaagtccg gaaagaaacg
    11341 ctggatttgc aattggtcca tataaagaag gaagatcctt tgttttcctt tttcggtgag
    11401 caagctgttt gttttaagcg cttatattat ttgaacaatc agccttatat ttattttgtt
    11461 cattatcttc cacaagaaat gatgcaattc agcagagaag aatttggcaa agaatctttg
    11521 tatcgtttgc tgacgaaaaa aggatatact attgactcat tttctgatga tttctcggca
    11581 gtatttttaa cagaagaaga acaaggaatt ctgaaaacag acgcacagat cggcatcaaa
    11641 cggatacgga aatcgtctac gcaaattggg gaaatgattg aatattcgga ggcggtctac
    11701 catacggagc tgcatcctta ccatattgat tatgaaacat aaataaaaaa agaggttgtg
    11761 aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagctt ctcatatttt
    11821 tcgtttggtt aggcttatta ccgcagatac acggctgttt ctggattacc atttattctg
    11881 gataaggggg tgtggcacga ttttcagaag gaatctatga accaatcact gtattgattt
    11941 tagcttcgat ggtaacccca ttcggcttga cgatcgctta tttcttaggg aaaatcattc
    12001 gtaaaaatat actcaatcgt caagaaatcg atacattgaa gaccgctttt cctatgggga
    12061 tctgtcagat cacagaggga tgtttcccta tcgtattgaa cgacttggca cgcaatgtca
    12121 tagcaacggg agtcggtggg acagtaggtg gcggattaag catgttttgg ggcgcagata
    12181 gccgtattcc ggcatcggga atgtttgcag tcgctacgat gaccagacca tgggcattca
    12241 ttggtgcatt gttagctggt tcttttgtca caggaataac cattttatta ttgaaaaaac
    12301 cagtagatcc gaatgcagaa atcatccaag aagaaaaaga ggaagaagac atatcttggg
    12361 atgatttgac aattagttag gagaggcaga atggattaca agaaaaaagt acaatagatg
    12421 taccttgaga caggaatggt atgaaagaat cagagttaga aagaatcgaa tatacagatt
    12481 ttggtttagg agcgatcgaa actgtccaga gcatcggcac cctccttgaa atgacgatga
    12541 aggaaaaatg agaacctttc gttgtcgaaa gggtctggta taccttatgt cgaaggaaag
    12601 gaaacaaaaa aactttcctg tactattcca aaaaggaaag aaagttatta tacagtaaaa
    12661 aaagaaatta ttcttcatgc tagagatcag tacacgttcg agcccaatat caaacactag
    12721 ttccaggcag gcgcaacagg tgcggttatc actgaatttt cttccagcag tgacgattca
    12781 agtgatattt ttacaaatcc agctatttat cgttaacaaa aagattttta ggagaagctg
    12841 atgaacaaaa atgatcaaat tttgatcgtt tagttcgtcg gcttttttat ttagagaaac
    12901 atcatttatc agtgaaacat aacacgagaa caaaatgatt ttttcgttaa taaaagaaac
    12961 aagtatttgt tgtttaaaat aatacacgtt attggcatat aggacgaaat cccagtatct
    13021 tctataagta agtcatttca tatcgatgaa aacacgttat ttatttttgt tttatctata
    13081 aaatggctga aaaatgattt ttttctaaat actatatata gtggcgtcta tcctatatac
    13141 cactaaaaaa ctacaaaatc tagtctttta ttttaaaaaa acacgtgtag aatgaagata
    13201 gacttttgag ttagggagtg tttttttatg aaacttactg ttttttgcgg ttcccgtttt
    13261 ggtaataaag aaagttacaa atttattgcg caaacgttag gaaaatacat ggcacaagaa
    13321 gaaatcgaac tggtttacgg tggttcatac tccgggatta tgggagtgat tagtaaaaca
    13381 gtactggaaa ataacggaaa agtcacaggt atctatccga atgggctttt tgaaactgaa
    13441 ttgcctggaa aagatgttac tacatttatt cctacagaaa cgatcgatga aagaaaggta
    13501 ttattatttg aaaagggaga tgctgtcctc gttttccctg gaggtctagg tacattggag
    13561 gaattctcac aacttctttc ttggatagca atcggtctga cgcccgacaa gccaatcgga
    13621 atattgaata ttggcggtta ttacagcggc ttgcaacaat tattagaaac ttttgcaaaa
    13681 gaggatttta tggataaaaa atggttggat caagtaatct tttccaacaa tccattggaa
    13741 ctggtcaatg aattacgagc agtatctatt aaaaatcagt tattattgaa ggaggcaaaa
    13801 taatgagtca aatatattta gcaggaccat ttttttcaga ggagcaaatc gatcgagtaa
    13861 gtcgtatcga aaaagcgttg gaggaaaaca aaacagtcac aagtttctac tctccacgtc
    13921 atcaccaaga aagcaattat gaactattca gcgctggatg ggcgcaggaa gtatacgaaa
    13981 aagatatgga agaactgaca aatgcagaat ttgttgttgc tatccttgac tttgagcatc
    14041 aaacaatcga tccaggaacg gcttacgaat taggtgtggc aactatgttg aaaaaaccga
    14101 tgatcattgt acaagaagag acggtaccta cgaacttgat gattacacaa agtctccata
    14161 cgtatttaaa atcagaccaa gctgtacgtg aatatgattt tgaaacattg cctgttgaaa
    14221 cttacgtagg cgagtactta tagaagagga agggttgtat gtcagtgatt ttgatttcag
    14281 gaacgattgg tgcaggtaag agcagtttga cggatatgct tgcaaaagag attgattcta
    14341 aaccatttta tgaaaatgtc gaagataacg aagtattgcc gctcttttat tcaaatcctg
    14401 agcagtacgc ttttttattg caaatcttct ttttgaacaa gcgattttta gcaatgaaaa
    14461 atgctttagt gaacgatgac aatgtgctag accgatccat ctatgaagat agcctgttgt
    14521 tccatctaaa cgctgattta ggtcgggtaa cggatatcga agtacagcag tacgatagct
    14581 tattagatac gatgctaaac gagttagatg atgttgctcc aaaaaaacgg cctgatttga
    14641 tggtccatat caaagtttct ttggacacga tgctagaacg tatcaaaaaa cgtgggcgtg
    14701 actatgaaca gctagaaagc gatgagacgt tatataccta ttatgaaacg ttgaacaccc
    14761 gctataatca atggtatgaa gattttgatg tatgtcctaa aatacaagtg gatggggata
    14821 aattcgattt tgtagaaaat ccagaagatg caaaaaaggt gatccgtcag atccaagaaa
    14881 aattagctga attggaagga aagcctgctg gaaaatattt tacggataac cagcatgcaa
    14941 aaggtcaaga attaggctaa aaataaaaaa ccaaacgacg ggaaagaaaa att
//
LOCUS       DAIGWC010000067        14815 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.068, whole genome shotgun sequence.
ACCESSION   DAIGWC010000067 DAIGWC010000000
VERSION     DAIGWC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.068"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(296..1024)
                     /locus_tag="NOB74_002183"
     CDS             complement(296..1024)
                     /locus_tag="NOB74_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HCI1221347.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="NOB74_002184"
     CDS             complement(1002..2576)
                     /locus_tag="NOB74_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCI1221348.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="NOB74_002185"
     CDS             2805..3743
                     /locus_tag="NOB74_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1221349.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="NOB74_002186"
     CDS             3755..4666
                     /locus_tag="NOB74_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1221350.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="NOB74_002187"
     CDS             4690..6162
                     /locus_tag="NOB74_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI1221351.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="NOB74_002188"
     CDS             6213..6824
                     /locus_tag="NOB74_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI1221352.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="NOB74_002189"
     CDS             6854..8767
                     /locus_tag="NOB74_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HCI1221353.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="NOB74_002190"
     CDS             8895..11876
                     /locus_tag="NOB74_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HCI1221354.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="NOB74_002191"
     CDS             11873..13534
                     /locus_tag="NOB74_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HCI1221355.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="NOB74_002192"
     CDS             13574..14506
                     /locus_tag="NOB74_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HCI1221356.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4815 a         2333 c         2978 g         4689 t
ORIGIN      
        1 atttaaataa ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagt
//
LOCUS       DAIGWC010000068        14795 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.069, whole genome shotgun sequence.
ACCESSION   DAIGWC010000068 DAIGWC010000000
VERSION     DAIGWC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.069"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            143..955
                     /locus_tag="NOB74_002193"
     CDS             143..955
                     /locus_tag="NOB74_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HCI1221357.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            952..1752
                     /locus_tag="NOB74_002194"
     CDS             952..1752
                     /locus_tag="NOB74_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HCI1221358.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1913..3181
                     /gene="rseP"
                     /locus_tag="NOB74_002195"
     CDS             1913..3181
                     /gene="rseP"
                     /locus_tag="NOB74_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HCI1221359.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3249..4958
                     /locus_tag="NOB74_002196"
     CDS             3249..4958
                     /locus_tag="NOB74_002196"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCI1221360.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            5170..9528
                     /locus_tag="NOB74_002197"
     CDS             5170..9528
                     /locus_tag="NOB74_002197"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HCI1221361.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9673..10146
                     /gene="rimP"
                     /locus_tag="NOB74_002198"
     CDS             9673..10146
                     /gene="rimP"
                     /locus_tag="NOB74_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HCI1221362.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10169..11344
                     /gene="nusA"
                     /locus_tag="NOB74_002199"
     CDS             10169..11344
                     /gene="nusA"
                     /locus_tag="NOB74_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HCI1221363.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11366..11659
                     /locus_tag="NOB74_002200"
     CDS             11366..11659
                     /locus_tag="NOB74_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HCI1221364.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11656..11967
                     /locus_tag="NOB74_002201"
     CDS             11656..11967
                     /locus_tag="NOB74_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HCI1221365.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11980..14286
                     /gene="infB"
                     /locus_tag="NOB74_002202"
     CDS             11980..14286
                     /gene="infB"
                     /locus_tag="NOB74_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCI1221366.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14313..14660
                     /gene="rbfA"
                     /locus_tag="NOB74_002203"
     CDS             14313..14660
                     /gene="rbfA"
                     /locus_tag="NOB74_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HCI1221367.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         5060 a         2605 c         3278 g         3852 t
ORIGIN      
        1 atatttcttt tatttaaaaa ttaaaaaaag aaaaaattat tcagttttta aataaaaaaa
       61 caatgatttc ataggaaaaa cagttagata ttgctataat acttaagata gtgggaatct
      121 tttaagtata ggaggaaaaa gaatgttacg tttttttccg caaaaaaaca aatatattca
      181 agaaaaaagc gaatttcaat ttaataccga tggaccaatt cctcagcaca ttgccatcat
      241 catggacggc aatggtcgtt gggcgcaaaa ccgtcgtttg ccacgagttg ctggccataa
      301 agaaggcatg gaaacagtaa agaaagtcac aaaaaaagca tcaaggcttg gagtgaaagt
      361 gttgacgctt tatgcctttt cgactgaaaa ctggaagcga ccaaaagatg aagtaagttt
      421 tctcatgcaa ctacctgtcg acttctttga tacgttcgta ccagaattga ttaaagaaaa
      481 tgtcaaagtt catgtcatgg gttatgaaaa cgtattgcca gaacatacgc aagatgctgt
      541 aagacgtgca attgagcaaa caaaaaacaa tactggaatg gtattgaatt ttgctttgaa
      601 ttatggaagc agagcagaga tcgtgactgc tgtccaagaa attgccgaag aagtagcaaa
      661 aggagaaata cacgcagaag aaatcgatga tgaattgatt gctaagcatt taatgacagg
      721 tttcttgcct aaagagttac aagatcctga gctgatgatc cgtacaagtg gagaagagcg
      781 aattagtaat tttctgttat ggcagatcgc atatagtgag ctgtatttta caaaagcgct
      841 ttggcctgat tttgatggtg cgcatcttga agaagcaatc gcctcttatc aaaatcgaga
      901 ccgtcgattc ggcggtgtaa aaaaaacaga agatgagaaa ggggatcagt catgaaacaa
      961 cgtgtggtca cagcagccgt ggcgctagtc ttgtttattc cgattatatg gatcggaggc
     1021 atagcggttg agcttacagc agcaatctta gcagtaatag gagtttacga gctgtttcgg
     1081 atgaaaggat tgacactctt aagttttgaa ggagttttat ccgccgttgg tgcagtgtta
     1141 cttgttttgc caaaagaaag atggtttttc tttcttccag agaatgtaag tacatttatg
     1201 ttattttatc ttatagttat gattctttta ggaacatcag ttatttctaa aaatacgtat
     1261 acgattgatg aagcaggttt tcctgtgctt gtcagcttgt atgtgggaat aggtttccag
     1321 aattttgtca atgcacgaac agaaagcttg gctgttttga tatttggtct atttattgtt
     1381 tgggcaactg atatcggagc atatatggtt ggtcgacgtt atggtcagca taagttaagt
     1441 cctgatattt cgcccaacaa aacgattgaa ggtgcgctcg gtggtattgg tagtgctgtt
     1501 gtagtcgcat ttctttattt attgctatac ccagcaaaag aactatttaa tcatggtatg
     1561 tttgtcatgc ttctgatgac gattattttt tcagcagtcg gacaatttgg tgatttggtc
     1621 gaatctgcaa tcaaacgtca ttatgatgtg aaagactcgg gaaatatctt accaggccat
     1681 ggtggaatct tagaccgttt cgacagtttg ctgtttgtat ttcctatcat gcatttattt
     1741 ggcattattt agtaagtata cctgcgtttc tttgtgaatt tcataaaaga cgcaggtttt
     1801 tatttttcat tatattgata ctattggtgt ctttggtata ctatggtaaa attatagtgt
     1861 tttatcgttg ttttataaaa aacacaaaaa acaagtaaag gagaaaaaag ctatgaaaac
     1921 gattctgaca tttatcatcg tttttggtat attagtgatt gttcatgagt ttggtcattt
     1981 cttctttgcg aaacgatcag gaatcctcgt tcgcgaattt gctatcggta tgggtccgaa
     2041 aatttatggg catcaagcaa aagacgggac aacatatacg cttcgcctat tacctattgg
     2101 cggttatgtt cgaatggcag gcaatgggga tgatgaaaca gaaatggcac caggaatgcc
     2161 tctttctctt ttactaaatt ctgacggcat cgtagagaag ataaatttaa gtaagaaaat
     2221 ccaattgaca aatgctatcc cgatggaatt gagccgttat gatttagaag atgagctgac
     2281 tatcactggt tatgtgaatg gagacgaaac agaagtagta acctaccctg ttgatcacga
     2341 tgcgacgatt attgaaaacg acggaacaga aatcagaatt gcgccaaaag acgtacagtt
     2401 ccaatcggct aaattgtggc agcgtatgct gaccaacttt gctggaccca tgaataactt
     2461 tattttggca atcctgttat tcatcattct ggcatttatg caaggtggtg ttcaagtgac
     2521 gaacactaat cgcgtaggag agatcatgcc taatggagct gcggcagaag caggcttaaa
     2581 agaaaatgat gaggtagtca gtgtggacgg aaaagaaatc cattcatgga atgatctgac
     2641 aacagtcatt acgaaaaatc cggataaaac attagacttt aagatcgaac gagaaggtca
     2701 ggtgcaatct gtcgacgtga caccgaaatc tgtagagtca aatggcgaaa aagttggcca
     2761 acttggtata aaagccccaa tgaatacagg ttttatggat aagatcattg gagggacgcg
     2821 tcaagctttc agcggttcat tggaaatttt caaagcctta ggatcactat ttacaggttt
     2881 cagtttagat aaattaggcg gacctgtcat gatgtaccaa ttgtcttcag aagcagcaaa
     2941 tcaaggtgta acaactgtta ttagtttgat ggcgcttctt tcaatgaatc tcggaatcgt
     3001 caatctgctt ccgattcctg ccttagatgg cgggaaatta gtcttgaata tttttgaagg
     3061 gattcgcggg aaaccattaa gtcaagaaaa agaaggaata ttgacattag ctggctttgg
     3121 atttttaatg ttgttgatgg tgctagttac atggaacgat attcaacgat tctttttcta
     3181 gaaaaagttg acaaataggg tataataaca aacgataact attttgagga aataaaggag
     3241 tatatagaat gagacaatca aaaatgttga ttccaacatt acgcgaagtt ccaaatgatg
     3301 cagaagtatt aagccatcaa atcttgctaa gagctggata tatccgccaa gtatcagcgg
     3361 gtatttattc atatctgcca ttagcaaatc gtgtattgga aaaactgaaa cgcattatgc
     3421 gggaagaatt tgaaaaaatc ggagcggtag aaatgctgat gcctgccatc ttgccagcag
     3481 aactttggga agaatccggg cgttacgaaa catatggacc aaacttgtat cgtttcaaag
     3541 accgcaatga tcgaaaaatg atccttggac caactcacga agaaactttt actgatttga
     3601 tgcgtaatga aatcaattca tataagaaat tacctttaaa tctttatcaa atccaaccta
     3661 aatatcgtga cgaaaaacga cctcgcttcg gtttgcttcg cggaagagag tttatcatga
     3721 aagatgcgta ttctttccat gcaacggaag aaagtttgga cgagacatat aaagattacg
     3781 aaaaagccta caccgaagta ttcaagcgtt gtggcttaga atttcgctcg attatcggag
     3841 acggtggcgc aatgggcggg aaagactcaa aagaattcat ggcgatctca gaaatcgggg
     3901 aggatacgat ctgttattcg actgaaagtg attatgctgc aaacttggag atggctacaa
     3961 gctactatgt atcaaaaaaa tcgcatgaaa cacagcttga attggagaaa gtagctacac
     4021 ctaacgtaaa atcaattgac gaagtagcag atttcttttc tgttgaacct caaaaaatca
     4081 tcaagtctgt attgttcatt gcggatgaac aacctgtcct tgttttggta cgcggagacc
     4141 atgaagtcaa tgacgtaaaa ctgaaaaact ttttatctgc tgacttttta gaagaagcaa
     4201 cagaagaaga agcacaaaaa tatctaggtg ctgagtttgg ttctgtcgga ccagtcggtg
     4261 tttcagatga cgtaaaagta tatgcagacc gttatgtcca agatttagcg aatgccatta
     4321 ctggagcgaa cgaaacagga ttccactata aaaatgtgaa tccagaacgc gatttcactg
     4381 tactttctta tgaagatctt cgttttgtac aagaaggaga tccttcacca gacaacaatg
     4441 gtgttcttgc ctttactcga ggaatcgaaa tcggacatat cttcaaaatc ggcactcgtt
     4501 acagtgaatc tatgggagca actgtactag acgaaaatgg acgagaaaaa tttgtgatta
     4561 tgggctgtta tggtatcggt gtaagtcgtt tattatcagc aatcgtagaa caacattcag
     4621 atgaacaagg aatcaactgg ccaaaaggaa ttgcgccatt tgatttgcat atcgtccaaa
     4681 tgaatctaaa agacgaatac caaacaaacc tgacgaatga actagaagaa gcgatgacaa
     4741 aagctggcta tgaagtactg gttgatgaca gaaatgaacg cgcaggagtg aaattcgcgg
     4801 attctgattt gattggctgt ccaatcagaa tcactgtcgg taaaaaagca gtggatggaa
     4861 tcgtagaagt gaaaatcaag aaaactggcg aaatggttga agtacgtaaa gaagaattgg
     4921 tgaatacttt accaatcctc ttgaaccaag gcgaataata agcgttaaaa cacagaaaat
     4981 aaaaatagct gaatcagctg tttttgacaa tctgatgatt cgcttttaaa attggaactg
     5041 cgatttgaat cgcagttcca attttttaat gtaaaactca gaaaaaacga gtatactaaa
     5101 aggtactgaa aaagaagagg ataagatgcg atcaattgca ttgtttctca tcagaaaggg
     5161 cgtatatctt tgtcagaaaa acgagattta tttgaaaaac tgttggaaca aatccaacta
     5221 gaggaagcag aaaaaaatca tccactgctt actgctggtg aaatggatag tgtagtggtc
     5281 catcgtaaat cgcgtttatg ggaatttacg ctgcattttt ccaaaatttt gcctattatg
     5341 ctatatcggt cattgactca gcatctgact atcgctttta aagatattgc acaagtcaaa
     5401 ctgaatatct tagcagatga ccagacattc gatgaacagc tcttgcaaga ttactgggcc
     5461 caagctttgg aaaatcagca atgcgataca ccactagcac agcaagtatt gaaaacgcag
     5521 gtacctgtga taaaagatcg taaagtcatc ttgccaatcg acagtacagg agctatttct
     5581 tatttgaagc aacaatactt gccattagta gaagagttgt tcgtcagtta cggattccca
     5641 aaatttcgta tcgaaccaga agtggatgag cagcaagcgg aacgagtatt gaaacttttt
     5701 gaagaacgca aacaagaaca ggcagaagcc tttatgaagc aagcagctga aagtctagtt
     5761 gtccacgaac aaaagaaaaa ggaaagaaaa gagcaatcgc cagctcttga aggacccatc
     5821 cacatccagc taggacgaaa tattccagcc gatgaaccaa cgacaccaat gatcagtatc
     5881 gttgaagaag aacgaagagt cacacttgag gggtacgtat tcgacaaaga agtcagagaa
     5941 ctacgttcaa aacgcaagat cttgactttg aaaatcacag attatacttc atcatttatc
     6001 gtcaaaaaat tctcgaacgg cgaaaaagat gaacaagtat ttgatgcgat cagtgtcggt
     6061 agctggttaa aggtacgagg aagtattcaa gaagatacgt ttgtccgtga tttggtcatg
     6121 aatgcgcaag atatcataga agtcaaacat acacctcgca aagattatgc tcctgaaggg
     6181 gaaaaacgag tagagcttca tgttcatagc aatatgagta cgatggatgc aacaaacagc
     6241 atctctgatc ttgtggcaca agcagggaaa tggggacacc gagctatcgc cattacagac
     6301 cacggtggtg cgcaagcctt tccggaagca catagtgctg gaaaaaaagc aggtgtgaaa
     6361 atcttatacg gcgtggaagc gaatgtcgta gatgatggtg tcccaattgc ttataatgat
     6421 gcacatgaag cattgagtga agccacatat gtcgtatttg acgtggaaac gacaggattg
     6481 tctgcagtat atgacacgat catcgagcta gccgcagtca aaatgtataa aggaaatgtg
     6541 atcgaaagct ttgatgaatt tatcgatcca ggacatcctt tgtcacgaac aacggtagat
     6601 ctgactggta tcacggatgg aatggttcga ggatcaaagt cggaagaaga agtattgcgg
     6661 atgttccttg aattttcaaa agatacaatt ttggtagccc acaacgcggc ttttgatatg
     6721 gggttcttga atactagcta cgcaaggtat ggtattcctg aagcggccaa tccagtcatt
     6781 gatacgttgg aattagctag atatctgtat cctcaattca aacgtttcgg attaggtgtg
     6841 ttatctaaaa aatttggtgt cagcttggaa cagcatcacc gagcaatcta tgatgctgaa
     6901 gcaactggtc acttagcatg gatctttgtg aaagaggcaa tggacaatca taacatgctt
     6961 tatcatgatc agctaaatga gcatatcgga gaaggagatt cttacaaaag ggctcgacct
     7021 ttccatgtaa cgattttagc aaaaaatcag gcaggactga aagatttgtt caaactgatt
     7081 tcaatgtcga atgtcgaata cttcgaacgc gtcccacgaa taccacgctc ccaattgaaa
     7141 aagatgcgtg aaaatctatt gatcggctca gcttgtgata agggagaaat attcgaagcc
     7201 atgatgcaaa aaggggtaga agaggcaaga aaccgagcaa aattctacga ttatattgaa
     7261 gttatgccaa aagcggtcta tgcgcctttg atcgagcaag aattggtaaa aaatgaacat
     7321 gatttggaag aaattatcca aaatttggta gaaatcggaa aaagtttgga taaaatcgtt
     7381 gttgcaacag gtaatgtaca ttatctgaac gaagaagatg ccatttaccg aaaaattttg
     7441 atcaattcta tgggcggagc gaatccgttg aatcgtcata gtttgccgga tgtccatttc
     7501 cgaacaaccg atgagatgct aactgcattt cactttttag gggaagaaac agcgaaagag
     7561 atcgtagtag aaaatacgaa taaaatcgca gatatctgcg aagaagtgat tccagtcaaa
     7621 gatgaacttt atacaccgaa gattccaggt tcagaagatg aaatatcaga attgagttac
     7681 acaaaagcaa aacaaatgta cggagatccg ttacctgaga tcattcaaaa acgattaaaa
     7741 aaagagttga attctattaa tggtaatggc ttctcggtta tttatctgat cgcccaaaaa
     7801 ctagtgcata aaagtaatga agatggctat ctagtaggtt cacgtggctc tgttggctct
     7861 agctttgttg cgacgatgac aggaatcact gaagttaatc cgttagcccc tcattattat
     7921 tgtccagagt gccaatattc cgagtttttt gaagatggta cgtatggttc tggatttgac
     7981 atgccagaaa aacaatgtcc aaaatgtggt gcacgcttaa acaaagacgg tcatgatatt
     8041 ccatttgaga catttttagg attccatgga gacaaagtgc ccgatattga tttgaacttc
     8101 tcaggtgatt atcaagcaga agcccataac tatacgaaag tattgtttgg cgaagactat
     8161 gtttaccgtg ccggaacgat tggtacagtc gccgacaaaa cagcatatgg ctatgtaaaa
     8221 ggatacgaaa gggacaataa tctgcagttt cgaagtgcag aagtcgacag attagcaaaa
     8281 ggcgctactg gagtcaaacg gacaaccggc cagcatccag gggggatcat cgttattccc
     8341 gattatatgg atgtctatga ttttacgccg atccaatatc cagcagacga tcaaaattcg
     8401 gaatggaaaa cgactcattt tgattttcac tcgattcacg ataatgtatt gaaattagat
     8461 attctagggc atgatgaccc aactgttatt cggatgcttc aagatttatc agggatcgat
     8521 ccacaaacga tccctacgga tgacccggaa gtgatgcgga tatttgccgg tcctgaagta
     8581 cttggagtaa gtcaggaaca aatttattcc aaaacaggga cattaggtat tccagaattc
     8641 ggcactcgtt ttgttcgagg gatgctagaa gaaacgcatc ctacaacttt tgcagaacta
     8701 ctgcaaattt ccggactatc tcatggtaca gacgtatggt taggaaatgc ggaagaattg
     8761 attcgacgag gagatgcgac actggcggaa gtaatcggct gtcgtgatga tattatggtt
     8821 tatttgatcc atgctggatt agatagcggg atggcattta aaatcatgga aactgttcgt
     8881 aaaggacaat ggaacaagat ccctgatgaa ttgcgagaaa cctatctatc ggcgatgaaa
     8941 gaaaataatg tgcccgactg gtatatcgat tcttgttcaa aaatcaaata tatgtttccg
     9001 aaagcccatg ctgcagctta cgtattgatg gctcttcgtg tcgcttattt caaggtttat
     9061 ttccctattt tgtattactg tgcatacttt tctgtacgtg cagacgactt tgatctagtc
     9121 tccatgtgca aaggaaaaga tgctgtgaaa caagcaatga aagaaatcac ggacaaagga
     9181 ttagatgctt ccgtaaaaga aaagaatcaa ctgacagtgc tggagttagc caatgaaatg
     9241 ctggaacgag gattcaaatt tggaatgatt gatttgtata aatcggatgc cgttaacttt
     9301 gttattgaag gtgatacgtt gatcgcacca tttagagctg tcccaagttt gggaaccaac
     9361 gtggcaaaac aaatcgttga agcaagaaaa gacggtccat ttttatccaa agaagatctt
     9421 gccacccgcg gtaaagtttc aaaaacattg atcgaatata tgaacgacaa tggcgtattg
     9481 aaagatctac cagatgaaaa tcaattatcg ttattcgata tgctataagc atctgttttc
     9541 ctgtctgctt gtaattttaa gcagagtatg gtatagttct tataggtaat gatactaact
     9601 gtgagtgagc ggatttttcg ctcactcttt ttaatggaat tacgcactta attttttaag
     9661 gaggcgaaac ttttgagtag cgtcgttgaa acagtcacag aaatggtgac accgatttta
     9721 gatgaacaaa attttgaact tgtcgaagtc gaatttgtaa aagaaggaaa aagctggttc
     9781 ttacgagtat ttattgacaa agaaggcggt atcgatatcg aagaatgcgc ctttgtcagt
     9841 gagaaactga gtgaaaaact tgatgcagca gatccagatc cgattcctca agcttatttc
     9901 ctggaggtat cctccccggg agcagagcgg ccattgaaaa aagaaagcga ctatgaaaag
     9961 gcacttggtg attatgtcca tgtctcctta taccaaccag tagatggcga aaaacaatat
    10021 gaaggatttc ttcaatcatt tgatgctgaa cagcttacat tgaaaatacg cataaaaaca
    10081 cgagaaaaag aattgacttt tgaccgaaaa aatattgcaa aagctcgctt agctatccaa
    10141 ttttaatcac ggagaggaat cagaaaaaat gagtaaagaa atgttaaatg cgttagacgc
    10201 tttagaagct gaaaaaggga tctcaaaaga aatcgtgatc gatgctttag aagcagcatt
    10261 ggtttctgca tacaaacgtc actatggcca agcacaaaac gtcgaagtgg aatttgatca
    10321 gaaaaaagga aagatccatg tctatgcggt aaaagaagta acggaagaag tgatggattc
    10381 acagttggaa gtctcattga aagatgcact tttaatcaat ccagcatatg agatcggtga
    10441 tacgatccgt tttgaagtaa caccaaaaga ttttgggcgg atcgctgcgc aaacggctaa
    10501 acaagttatt ttacagcgtg tacgtgaagc agaaagaacg attatttata acgaattcag
    10561 tgcttatgaa aaagacatca tgcaaggaat cgtcgaacgc caggataaac gttatattta
    10621 tgtcaatctt ggtaaaattg aggcagttct ttctaaacaa gatcaaatgc caaatgaatt
    10681 ttatcaacca catgatcgaa tcaaagttta tgtttcccga gtagaaaata cgtctaaagg
    10741 tccgcaagta tttgttagcc gcagccatcc agacctattg cgccgcttat ttgagcaaga
    10801 agtaccagaa gtctatgatg gaatcgttga aattgtcagc atcgcccgtg aagctggcga
    10861 tcgttcaaaa gtggcagttc gctcaaatga tccaaatatc gatgcagtcg gtacatgtgt
    10921 cgggccaaag ggacaacgag ttcaagcaat cgtcaatgaa ttaaaaggcg aaaacatgga
    10981 tatcgtcgaa tggaatgaag atccagctgt attcattgca aatgcattga atcctgcaca
    11041 agtcatggat gtgatcttcg atgagacaaa tccaaaggcc tgcacagttg tcgttccaga
    11101 ctaccaatta tcgctagcaa tcggtaaacg cggacaaaac gcacgtttag ctgctaaatt
    11161 gactaaccat aaaatcgata tcaaatcaga atctgacatg acggaatttt atgaaaatca
    11221 agaacaacaa aaagaaacag aagaactgca tgatgaagca atcgttcagt cagatttaac
    11281 agacgatgaa tatgaaacaa ttgcattcaa caatgaaacg gtcgaagaaa aaccagaagc
    11341 ttaactttag taaggaggca aagagatgaa acaaaggaaa attcctttac gcaaatccgt
    11401 ggtttcaggt gaaatgaaac ctaaaaaaga gatggtccga atcacccgtt caaaagaagg
    11461 ggaagtatcg atcgatccaa ctggaaaaat gcctggacga ggagcgtatg tctcacttga
    11521 gccggaagaa gtacaacaag cttgggataa aaaaattctc gatcgagtac tcgaaacaac
    11581 attaacagat gagttttatc aagaacttct tgactatgtc actcaccaaa aagcacgtaa
    11641 agagttattt ggaaaatgaa tacagttaat cggcaaaaag ccatgaatct catcggtcta
    11701 gcgatgcgcg cgggaaaact aatcacgggt gaagaactga ccattgctga aatccgcaaa
    11761 caaaaagcaa aattggtgtt tgtggcaacc gatgcaagcg agaatacaag aaaaaagata
    11821 aaagataaga gttcatatta tgaagttcct tgctttgagc tattttctga agcagaaatc
    11881 acgcagatga tcggaaaacc tcgcaaggta ttcggaataa tggatgccgg atttgcgaag
    11941 aagaccaagg agctaattga aggttaggaa ggtgattgca tgggcaacaa aagaatctat
    12001 gaattagcaa aagaactcaa aaaatctagt aaagacgtcg tggaaaaagc acaacaactt
    12061 ggcatcgatg tgaaaaacca tatgggtgcg attactagca atgatgagaa gaaattgcaa
    12121 caagcgttca aaaacccaag cacgaaacaa caagctgcac aacaagcaag cagaaaacca
    12181 gccaatcaac agccgaacga tcaacgtaaa aaagaaacaa cgaacaatca acaaaaaaat
    12241 aaaaataacc gcagttatca agatcgcggt caagggagcg gtcaagtgaa tcaaggaaaa
    12301 aaaccaacaa caaaccaaaa taatacggga aataccagca gccaaaatcg tcaaggaacg
    12361 agccaaggcg gcaatcaaaa ccgtactaac aataacaaca aaccaaacaa taacaatcgc
    12421 ggcaaattta ataataataa ccgtaatcgt tataataaaa aaggtaaaaa aggcaaacag
    12481 caacaatcaa ctaaaccagc tgtaccacca cgcaaattcc gtgaattgcc agatgtatta
    12541 gagtatactg aaggtatgaa cgtagcagat attgcgaaaa aaattcatcg tgagccagca
    12601 gaaatcatta aaaaattatt tatgcttggt gtcatggtca atcaaaacca agcactggat
    12661 aaagatacga ttgaactgtt agcgacggac tatggcatgg aaccacaaga aaaagtccaa
    12721 gttgacattg ctgatatcga taaattcttc gaggcagaag aagtcgatcc agataaatta
    12781 gtctcacgtc cgccagtcgt aacgattatg ggacacgtag accatgggaa aacaacttta
    12841 ttggatacat tacgccattc acgtgtaaca agcggcgaag ccggcggaat cacacagcat
    12901 atcggtgcct accagatcga tattgatggt aaaccaatca ctttcttgga tacaccagga
    12961 catgcggcct ttacaagtat gcgtgcacgt ggagcaagta tcacagatat cacgatctta
    13021 gttgttgctg cagatgatgg cgtcatgcca caaacagttg aagcaatcaa ccatgccaaa
    13081 gctgcaggcg ttccaatcat cgtcgctgta aataaaattg ataaaccagg tgcaaaccct
    13141 caacatgtta tgcaagaatt aagtgagtat gagttaattc ctgaagcatg gggtggagaa
    13201 acgatctttg ttgagatctc agcgaaattc ggccaaaaca tcgaagaatt gctggaaatg
    13261 atcctgttag tcgcagaagt agaagattta aaagcagatc caacacaacg cgcaatcgga
    13321 acagtgatcg aagcacgtct tgataaaggt aaaggtcctg tgtcaacctt acttgtccaa
    13381 gaaggaacac ttcatgttgg tgacccaatc gttgtcggta atacttacgg acgtgtccgt
    13441 gtaatgacaa acgatcttgg ccgtcgcgat aaagaagcag gacctgcaac gccagtagaa
    13501 atcactggct tgaatgatgt acctcaagca ggtgaccgtt tcgtagtctt cgaagacgaa
    13561 aagacagcac gtgcagcggg tgaagaacgc gcgaaacgtg cattattaga aaaccgtgct
    13621 gccacaagcc gtgtgacttt ggataactta tttgaaagcc tgaaagaagg cgaattgaaa
    13681 gaagttaacg taatcatcaa agcagatgta caaggttcag cagaagcact ggctgcatca
    13741 ttgaagaaga ttgatgtgga aggtgtccgt gtaaaaatcg tccattcagc tgtcggagca
    13801 atcaatgaaa gtgatgtaac cttagcagca gccagcaacg ctattatcat cggtttcaac
    13861 gttcgtccta caccgcaggc aaaagtgcaa gctgatactg aagaagtcga tattcgtctt
    13921 caccgtatca tctataaagc catcgaagaa atcgaaactg cgatgaaagg gatgctagac
    13981 cctgaatttg aagaaaaaat caccggtcaa atgatcgttc gtgaaacctt caaagtttct
    14041 aaagttggta cgattgcagg tgcctatgta acagaaggat atattcgtag agatagcggt
    14101 gtccgtgtaa tccgtgacgg aatcgtaatc tatgaaggcc aacttgcaag tctgaaacga
    14161 ttcaaagatg acgtgaaaga agtcaaaatg ggttatgaat gtggtgcaat gattgaaaaa
    14221 ttcaatgaca tcaaagtaga tgacgtaatt gaaggattta tcatggaaga agtcaaaaat
    14281 gactaaaaac tgataaaagg aggccaatca ttatggctaa ctaccgtgac cgccgagtcg
    14341 gtcaagaaat cttaaaagaa gtcaatgata ttttgcgcaa aaaggtccgt gaccctcgtg
    14401 tggagaacgt aacgatcaca gatgtgaaag ttacggggga cttacagcaa gcaacgatct
    14461 attacagcat tttatctgac ttagcatcag ataagaaaac agcacaagat ggattgaata
    14521 aagcatcagg attgattcgt cgagagttag ggcacaatct aagtatttat aagacacctg
    14581 aattgttctt tgaacttgat gaatcagttg tctatggcaa ccatatcgat gaattgcttc
    14641 gcgacttgaa caaagactaa tcaaaaactc ccgcaaatcc tgtgaaatca ggggttgcgg
    14701 gatttttttg ttttcattaa gacgtattac ctaagagttc catgacttta gtcttgcggc
    14761 gtgtcagcta accaaaaaag agaaaaagaa aagta
//
LOCUS       DAIGWC010000069        13732 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.070, whole genome shotgun sequence.
ACCESSION   DAIGWC010000069 DAIGWC010000000
VERSION     DAIGWC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.070"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(143..1345)
                     /locus_tag="NOB74_002204"
     CDS             complement(143..1345)
                     /locus_tag="NOB74_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1221368.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1348..1542)
                     /locus_tag="NOB74_002205"
     CDS             complement(1348..1542)
                     /locus_tag="NOB74_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCI1221369.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1589..2437)
                     /locus_tag="NOB74_002206"
     CDS             complement(1589..2437)
                     /locus_tag="NOB74_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HCI1221370.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2642..2992)
                     /locus_tag="NOB74_002207"
     CDS             complement(2642..2992)
                     /locus_tag="NOB74_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221371.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3587..4033
                     /locus_tag="NOB74_002208"
     CDS             3587..4033
                     /locus_tag="NOB74_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HCI1221372.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4657..5649
                     /locus_tag="NOB74_002209"
     CDS             4657..5649
                     /locus_tag="NOB74_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1221373.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5665..6549
                     /locus_tag="NOB74_002210"
     CDS             5665..6549
                     /locus_tag="NOB74_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1221374.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6598..8205
                     /locus_tag="NOB74_002211"
     CDS             6598..8205
                     /locus_tag="NOB74_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1221375.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8206..9690
                     /locus_tag="NOB74_002212"
     CDS             8206..9690
                     /locus_tag="NOB74_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HCI1221376.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9867..10859
                     /locus_tag="NOB74_002213"
     CDS             9867..10859
                     /locus_tag="NOB74_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1221377.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10911..11780
                     /locus_tag="NOB74_002214"
     CDS             10911..11780
                     /locus_tag="NOB74_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI1221378.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12200..13693)
                     /gene="guaA"
                     /locus_tag="NOB74_002215"
     CDS             complement(12200..13693)
                     /gene="guaA"
                     /locus_tag="NOB74_002215"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCI1221379.1"
                     /translation="MITRRIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYD
                     EKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALF
                     QNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSE
                     YGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVL
                     LQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDP
                     EEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVG
                     GLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEK
                     LEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSI
                     DGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE"
BASE COUNT         4214 a         2322 c         2832 g         4364 t
ORIGIN      
        1 ttgaaaaacg ttgatttatc ggcattcccc atccatatta tatttacgtc ttattcccac
       61 tcaatatgag tagcctcgta aagaagctat tatatcagtg ctttttcagc ctattcctca
      121 ttttggtagg gaaatggtag ggttagattt ttactgcttg atttccatta aagtttgcaa
      181 ctttagattt tgttgcacag gtaaatttaa tgtttcctgt catttgttct gcaattcctt
      241 catcattacg gctccataga tgagcgtagt gctttaaagt gatttcaggg ctagaatggc
      301 ctaaccgttg cgacacgacc agaatgtctg cgttaaactc attgattagg tagctaacat
      361 gagaatgacg taatcctttt ccttgtatta ggggtacctt agctagtttg gcataacgct
      421 gaataattcg ttgaacagtt gaacgataga gtgggaggtc agtgtagcta agaataaatt
      481 gttctacacc atgatttttt tgaataactt tccacttttt tagcacttca attgtatcat
      541 cgtccagaga aatgatccgc aagccgcttt cagtttttgt gtaaggtttc cgaataaaat
      601 ctttttgatt tgtcatttcc aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca
      661 cgtcattcca attaagtgct aatccttcgc ttacacgaac accagtcatg taatatagcc
      721 agatcattaa aaaacacata tgttcgtaga aatcatcttt ataaattttt gccaaaactt
      781 cttcaaattc ttcttttgtc cagtaaggaa cgattgattt tccttttgga attgcttttg
      841 ttcttttgga aatattctca ttcagaaatt gcagggtgac cgcatagtct aatgatttac
      901 gaaacatacc gtacataagt gaactgtatg cttgtgagta tccgctatcg ttcaataacc
      961 aaattcgata attttcacaa tctcgcacat tgatttcacg aagcttctta tcaccgaaaa
     1021 attcagtaat ctgaatcaat ccacactcac gagaactcca agtacttttt tgtacgctag
     1081 ctttgtagtg tggaacgtaa gactgctcca taaattcttt gtaagttaaa tcataattcg
     1141 caaatccatt tacaaccatg tattcatttt ttatacgcat gacttctttg tgtgcttcac
     1201 gagctgatga gaatcgtttt cctagagaat cttttgttcc tttcttctgg atcctctttc
     1261 cagtcacttg atctgttcct aactcaacta gataagaaaa gcgaccattt ttatcttgat
     1321 acacacaagg gtattttgtt ttcatagtta ttcctcctgt gaaagaggaa cacctataat
     1381 ttcttcaatt acttgtcggg gtactacccc aactctttta ttattataat atggatatcc
     1441 ctgatttacc attcttgttt ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa
     1501 tcctagagcc tctaaatctt ttcgacaaat tgtatttttc attgtataaa ctcactttca
     1561 aagaaaacac tatcattggg taatagtgtt atttctttat ttttgtataa tgaacggtac
     1621 tttcttgaaa atccatcact tgttcaggac ttcccaactc atttaaagct aaagcattgt
     1681 aaaaaaatgg acgtctaact atatattcgc ttgtatatag tatatcttga ttcgtggaat
     1741 catagggttt ctttaccatc tttttggtga cagttggtag tttgagattc cgggacttga
     1801 aaaaagcttt tttcttatgc tctttcaatt ccagctcttt atcgaaatat ttgctgatat
     1861 agcgcccgcg attttcgata ctgtctacat cgatcttgtt gatcttaacg aaaccctgac
     1921 cccaaatcgt agttaaccgg ttaaatgaga taaaggggaa atcaaacaag ataatatggt
     1981 agtggattgc accgcgttgc tgcttttccc acgtggcgag atactttaaa tttgcttttt
     2041 tagttttata gaggtcataa ttcagtcgtt tgataaattt tttaaattca ttatttgcat
     2101 actcaatgtc ttgaatgttt tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa
     2161 aattcgtgtc tacaaggcgg gcaatctcaa atcgcatact ttgataatgt ttctgtttgc
     2221 gttttaaact gtcatattgt ccttgagcgg ataattcatc atagtttttt cttttttcaa
     2281 gagtaatatc attttcataa atccaagcta atttttgttt tcgttccaga tttacttcgt
     2341 tttcgatcgt tttacgtttg ggagtaatga ttgcttcata atcataaatt tcaatatacg
     2401 tgggagtttc aatgattttc tgattataag cttgcaaaaa tcatcactcc ttgttgcgta
     2461 ttcgattgtc aaagaaccag tcattttctc ctgatgttga tctataaatc aagttaaggg
     2521 ggaaggcctg cgtagcagcc cttctagcct atggggtgtt gggcggtctt aacggacaga
     2581 aacggctctg tgggcgctgc cccgccgttt cgtcctaacc acccaacact ccatagtata
     2641 gttagttttg tgtagtggta ccttgttttc tgggaatcaa agttgccgta tcagcggttg
     2701 ccgataaccc ataactgaca aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat
     2761 tggtaaatgt aattatggct aaaccttgtt gggtaagttc ttccggcgtg atcacaggat
     2821 gttcagattt gactttgaca ctgatttttt cgtagcgaag ttttggtagg atacattcgt
     2881 agctccaacc tagaatttcg ccctcctttt gccagcgagt gacattgacg acttggtatt
     2941 ctttttcgag tgtttctttt ggtaaactga gatcggtaat ttttattggc atcacaattc
     3001 tcctttttta tacgaaagtt tatacgattt gattaaaaaa tatagatggc catctacgac
     3061 ttgtattata tacgagaact tatacgtagt caagagattt tctaaaaaaa tatatacgat
     3121 tttttatacg agtgttataa tgaaaaaaat gataaggagg aatttgaata tgtttggttt
     3181 agtacaacct aataaagtga aggtgggcca acgaatcaaa gaaataaaag acggaatgtc
     3241 tctctctttt acagaattag ggaatcgatt aggtttaaaa aagccgacga tcagttccta
     3301 cgttcaaggc tatgcgttgg ctcctaagag tgtgatcaac caattatcta gtatcagcgg
     3361 aaaacctgtc ggctggtttt attttgggca tgtggaagaa tatatccgag agtatttgtt
     3421 tctcattggt cagaaaaaaa tagtggacga ttatcctgaa atcattgaga aaataaagca
     3481 agaattttat acgggcgagt tcaaaaatcc tgcttgggag aatgagctag gctatccttt
     3541 ggaggaattt atccaagaat gttttgtaga atattcgagt gaaatcatga aggactatgt
     3601 cgtacagatt acgaaagagg tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa
     3661 agcaaaagaa gaagctgtca cgattctttc atctgggatc attgactata tcgagatgag
     3721 tggtgagatc aagtatggag agaaagatcg cattgcgaaa atggtgaaag aatcaataaa
     3781 aacctttgat gtgaaacaag acctgacatt taatgattcc tatttgattg gaaagttgat
     3841 caatattctt ggtacagatg aagatacgga gctgtttctt tcttctttat caatgatatt
     3901 tactgataag catttttcca ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc
     3961 gatgcgacca gcgttaatca aactctatcg ggagaaaaca ccagatgaat tttatgattg
     4021 gtttgagaag taaaataaga aaagtggctt agattacaag ttggtgaaaa aatttttttc
     4081 agcataacat cagtaatcta taaaggggtt gttgattata ctgtagaagt taagtactca
     4141 agagattttt tgtacgtaaa caaagcaaaa aagggtgcag tttcactaga aaatgtactc
     4201 ttttttgtga tttttcttag ttatagagtt tttttgaaac tttaaaaatg agaaaacata
     4261 ttgattttaa agagtgtaga catagcttct tttgctaaat agattaaact tactggtgag
     4321 tggtcttgaa catactttta aatcacattt tactgagttt tattggattt tataattcat
     4381 tggaaacctc gtacttaatc tgtttttatc tatcgactag aatctgtata tattccagct
     4441 atcaatgagg ccgcagaaaa gggtgcttaa aaataatctg ttgtttaaaa tattattatc
     4501 agaatactta gatacaaaat tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg
     4561 atatggtaat ctataaacga aaatagtggt aacgtttcca aaatgcatct tcgttaaatt
     4621 tttatttttt taaacgaaaa tggaaacgtt tctaaaatgt attgggagga gattgaattg
     4681 gaaaagacat tgggaccagg tggtgagata agggcggtac aacgggataa aaaaaatatt
     4741 tcgaagtggg aaaaattaaa gaaacagttg cggcgtgata agtggatgta cttgttgctc
     4801 ttaccaggta tcatcatgac gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt
     4861 gcatttaaag actataatcc tatgctagga attttggaaa gtccttgggt aggactagat
     4921 cactttaggg aatttatcag ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa
     4981 attagtattt atggtttatt gttaggtttt tttccaccaa ttattttagc actgagcttg
     5041 aatcaaatta tcaataaaaa aataaaacag aaaatccagt tgattctata tgcgccgaat
     5101 tttatctcag tagttattat tgtggggatg ctgtttttgt tcctatccgc aaatggacct
     5161 attaatgggt tagtagaaaa ggttacgggg caaccaatta tgttcatgtc taatccagct
     5221 tatttcagaa cgatttatat tttatcggga atttggcaag gaatcggctg gtcatccatt
     5281 ctttacaccg caacgctggc gggagtcagt accgatttat atgaggcagc aaatatcgat
     5341 ggggcaaata ttttacaaaa gatttggcat atcgatttgc ctgcattgag gcctgtgatg
     5401 gtgatcagct tcatcttggc cgccggcggt attatgaatg taggatatga aaaagcctac
     5461 ttgatgcaaa cttcaatgaa catccctgcc tcagaaatca tttccactta tgtatacaaa
     5521 gtcggcttgc aatcaggtga ttatgcctac tctgctgctg ttggtctgtt caatatgatt
     5581 attaatgtcg ttttattact gattgtcaac aatataacca agcggctaaa cgatggtcaa
     5641 ggcttgtaat gaaaggagaa aattatgaat agtgctttat caaaaatcga ccgtcaaatc
     5701 ttatggttga atcgagtgat tgtaactttt ttagtcgtca tcaccattgt tccgctgatt
     5761 tatgtactgg tagcttcttt tatggaccca gctactttga tcaataaagg tataagcttc
     5821 aatccgaaag attggacaat acagggatat caacgggtat ttgcagatga ttccatttta
     5881 cgcggttttg taaattcgtt gttttactct tttagcttca gcttattgac tgtatttatt
     5941 acgatgatca ctgcgtatcc tttgtctcga cctaacttgg cggggaaaaa gattattatg
     6001 actttttttg tcattacaat gttcgtgggt ggtggcttga tacctaccta tttattggta
     6061 aagaacttgg gcatgttaga tagtgtatgg gcgattatcg taccaggtgc tataaatgtg
     6121 tggaatatta tcttagcccg tacctatttt agtgctttgc caaaagaact ttctgaagct
     6181 gctactatcg atggcgccaa tgacttgcaa atactgttca aagtcatgct tccattagcg
     6241 aaaccaatta tgttcgtatt gtttttatat gcctttgttg ggcaatggaa ctcatacttt
     6301 gatgccatga tttacatcaa agatcccgac ttacagccgt tgcaactcgt attaagaaat
     6361 attttgatcc aaaaccaacc ttcacaagac atggtgggag ccaatactgc catggcagaa
     6421 atgaaacaaa ttgctgagtt gatcaaatac gcaacgatcg tcatttctag tctgccatta
     6481 atcataatgt atcctttctt ccaaaaatat tttgataaag gtgttttagt tggttctgtt
     6541 aaagggtaag tattgttcac tatttgtatg aataaaaatt ataaaggaga ttttaagatg
     6601 aaagcaaaat ggatgctgcc aatcgttttt acttccgtac taattttggg ggcttgtgga
     6661 ggctcaaaag aaaagagtaa atcaagccct gattatgaac tagaaaatgt ctcttttcca
     6721 ttgaaagaaa aagtatcttt aaaaatgatg tctcaaagtg cccctttggc tcccaatgat
     6781 cctaatgaca aattgatttt ccaacgatta gaagaagaga ccaatctcca tattgattgg
     6841 acaaactaca gtagtgattt tgccgaaaaa agaaatttgg atatcgctag tggtgattta
     6901 ccagatgcca tcttcaacgc cgctgcaggt gactatgatt tattaaactg ggcggaaagt
     6961 ggcgttattg taccgattga agatttgatc gaagattata tgccaaatct gaagaaaatt
     7021 tttgatgaaa accccgaata ccgacaaatg tctactgcac ctgatggtca catttactct
     7081 atgccttgga ttgaagaatt aggcgaagga aaagagtcga ttcatacagt aaatgggatg
     7141 gcttggatca acaaggagtg gttggataat ttgggtcttg aaatgccgca aaccactgat
     7201 cagttgatga ctgtgttgga ggctttcaag acgcaagatc caaatggtaa tggtgaagca
     7261 gatgaaattc cttttagctt tattaacaat ggaggaaacg aagacttaaa atttttaatg
     7321 ggggcattcg gtctaggtga taatgatgac cacttagtcg ttgataacga tggtcaggta
     7381 caatttactg ctaacaaaga agggtataaa gaagccatca aatatttcaa tgaaatgaat
     7441 aataaaggtc ttattgataa agaggctttc gaacaagatt ggaatacgta tgttgccaaa
     7501 gggaaagaac ataagtatgg cgtgtacttt acttgggata aagcaaatat cacgggtgca
     7561 gatgatagtt atgacgtctt gccagtctta gcgggaccag atggaacgaa acatgttact
     7621 cgtacgaatg gcatgggttt ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac
     7681 ttggaactta cagctaggtg gatagataaa atgtatgaac cgttacagtc tgtccaaaat
     7741 aactggggaa cctacggtga tgaagcacag gcgaatattt ttgaattaaa ggatggtatg
     7801 ttaaaacatt tgcctttaga ggggacagca ccgggggaac taagacaaaa aaccgaagct
     7861 ggaggaccat tagcagttct tgattcttat tacggcacag tcactactat gccagatgat
     7921 gcgaagtggc gtttagattt gatgcatgac acgtatttgc catatattac agaagacaat
     7981 atctatccac gtgtcttttt agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg
     8041 gatatgtggg attacatcta tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat
     8101 gaagaatggg aagaatacct tgctgaattg gaacgtgtag gtttggaaga atggattcaa
     8161 ataaaacaaa ctggctatga taattttttg aagggagcac aataagtgtt agtagaagaa
     8221 acggcgattt tggataaagc aaatcgattt attgaaatga tgcgaggaaa agttaaccct
     8281 cagtatcgac aaaactatca tttttccgca cccatcgggt ggataaatga ccccaatggg
     8341 tttatatatt acaaagggca ttaccatctc ttctatcaat actatcctta cgatagtcga
     8401 tgggggccca tgcattgggg gcatgcgcgc agtagtgatt tggtccattg ggaagatcta
     8461 ccagtagcgt tagccccaga tcaaccttat gacagcggcg ggtgtttctc aggaagtgca
     8521 attgaaagag acggaaaact atatttattt tatacaggct gtcaagaaat tgatggtatt
     8581 agccatcagc atcaatgttt ggcggtctct gaagatggta ttcattttag caaatacagt
     8641 ggtaatcctg tggtagcaga aaaacagcta ggtgaaaatg ggctaataca agaatttcgt
     8701 gatcctaaag taattgttca caacgatggt tactatatgg tagtagctac taaatctaca
     8761 cagtctactg gtagaatagt gatgtttcaa tcgtcagatt tgtatacttg gcacttttac
     8821 tctgtgctgc tagaagggac ttcagagcaa ggaataatgt gggaatgtcc tgatttattc
     8881 catttagacg gacgagatgt cttaatcatg tctccgatac aaatcaagaa gaacggactg
     8941 gaatatcata atatcagttc taccatggct tgtattggtg aggtaaactg ggaaacaggt
     9001 cagatgatag ttgataattt ccatgaaatg gattttggaa tggattttta tgcaccacaa
     9061 acaacaagag atcctaatgg tggacgggtg atgattgctt ggatgcagat gtgggatcgt
     9121 acattgccta cacatgagtt aggccatctt tgggcaggct ctatgagttt gccccgagag
     9181 ttaagagtga aaaaaaatcg attggtacaa aaacccatct caactgtata tagtcattta
     9241 gtttatcaac aaggcagtga aaatattgca gtgactgaca catcagtcgt atttcgaaac
     9301 gcgctgtctg attcttcata tttacatcta gtcgcagatt tggagaaagc tgaagttttt
     9361 acaattgaat tactgcggtc taagacggat tgtctcaaac tagcctatga cactgctaca
     9421 caggtttttg aattggatcg tcagaaacta ggaagagagc ttacaggggc ggaagaagac
     9481 cctctgaatg tacgaaaagt tgaagtacct ttgattgata atcagctcgt tcttgagatt
     9541 tttagagata cctcatcaat tgaagtcttt attaatgggt tagaagttat gacggctact
     9601 ttctatgagc tggaaaaagc tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt
     9661 caagcttttg aaacagcgag tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt
     9721 atttaatagg ttttgaagga taatgttttt agaaaagaac agatagctag atttcccatg
     9781 gatttgctat tagtattttg aaaaaattag taatttatga caaaattcat tatactaaac
     9841 ttgtgcagaa atgtgaggga tcaactatga aagcaacaat gaaagatgtc gcaaaattag
     9901 caggtgttgg agtaggaact gtttcccggg tattgaataa cggttctgtt aaagcttcta
     9961 ctagagaaaa agttgaagca gcaatgacag agttaaacta tcaaccagat ttttatgccc
    10021 gggggttaaa gatgaagcat acgaacacgg ttgctttgat tctacccacg gtatggcatc
    10081 cattttttgg cgaatttgcc taccatgtag aaacagcatt agaaagacaa aactacaagc
    10141 tttatttgtg taactccagt ggtaatagtg aaaaagaaca agaatatatc cagatggtca
    10201 gccaaaataa agtagacggc atcattggaa ttacttattc agatatcgat gaatacattt
    10261 cgagtaatct gccttttgtt agtattgacc gttatttcac tgaagaggtg atttatgtga
    10321 ccgctgacaa tgcggccggt ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc
    10381 agaatgtagc atatatcggt gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa
    10441 aatattttga aatcgagtgc cgtcaactgg ggatttccta taaagcgtta gatatgttag
    10501 aacctttaga ccatctctca gaacgtgtaa caaatttttt gttagagaat cccgatatcg
    10561 atgggatttt tacgatcaac gatccaatgg cattagctgt cattgatatg cttgaaaaaa
    10621 tagggaaaaa cgtaccagag gatgtccaag ttatcggatt tgatggtcaa aagatgacag
    10681 aaggagatcc ttatctagtc tcaacgattg cccaacctac aaagcaaatg gcggaagtgg
    10741 cagtggcaaa attaattgct gtcattaatg gagagacagt agaaaaacgt accgtattgc
    10801 cgattgaatt tggcgaaggt gacacaacga aacctttagt gagaaacgat tttgcttagt
    10861 gcaaatacgt ttcttttttt gaaaatgagt gaatgaaagg tgtagataaa atgttatatg
    10921 gtggaataga agccggtgga acaaagtttg tctgtgggat tggtaatgaa caattacaag
    10981 tgatagaacg gaaaagtttt cctaccacaa caccagaaga aacgatggag caagtgtttg
    11041 atttctttga taagtacaaa ggaaatatcg catcaattgg tgtaggagca tttgggccta
    11101 ttgatattca aatcgaatca agaacttacg gatatatcac caacacaccg aagttagctt
    11161 ggcaaaatta tcattttgta ggagctttgg aaaacgcctt gtcggttccc atctattgga
    11221 ctaccgatgt aaatgctgct tgttatggag aatatatggc agggtatgga aaaggtaaaa
    11281 atagtgttct gtattacacc gttggtacag gtgttggtgg tggtgctgta gtggatggga
    11341 aaatagtcgc aggttttagt catcctgaaa tgggacatat gctcttacaa cgtcataatg
    11401 aagatcaatt tgaaggaatc tgtccttttc atcatgattg tttggaaggg ttagcatcag
    11461 gacctgcgat tgaaaaacgc tttggaagaa aagcccagac tatctcattt gatcatcctt
    11521 attggacgat tgaggcagat tatcttgctc agtgtgtgta taacacaacg ttactatatg
    11581 caccggaagt aataatttta ggcgggggtg taatgaaaca gccgcaacta ctcgagttga
    11641 ttcgccaatc gtttaaagaa aaaatgggtt cctacgtgga tacgcctact ctcgaagaat
    11701 atctactaac tccaaggctt gctgacaatg cgggcttgat tggctgccta gctttagcaa
    11761 taaagaaact caatcattag aatagtattt attagaacta ttcataacat accggaagtt
    11821 taaaagggta ttctgaaact taaatagtct caattcattc ttctttcttg agaatctgag
    11881 tagagacttt tattctgttt caaattaata taattacgaa atgatattga gtacaagaaa
    11941 gttcttttta ccagatcttt taaatcgaaa aatctgatat atatatttat agtactaaaa
    12001 atctgattag ataaaaagct aattcaatag gaaaataaag gtagtgaata aaagcaaagc
    12061 ccttgttagt agttaatcta acaagggctt tggtagggaa aatggtagga aaccatctta
    12121 ttttttacga aaatcaggaa ctttagtaat tgaataatgt tgatttatag gtattcctca
    12181 tccatattat gttggctctt tattcccact ccactgttgc aggtggtttg ctggtaatat
    12241 catacacgat acggttaacg tgtgcgactt catttacgat acggacactg attttttgca
    12301 agacttccca agggatacgg gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac
    12361 ggatacctac agtgtagtca tacgtacggc catctcccat aaccccaaca gagcgaatgc
    12421 ctggtaggac ggtgaagtat tgccagatgt cgcgatctaa accggcattg gcgatttctt
    12481 cgcgcaagat agcgtctgat tcacggacga tttctaattt ttcttctgtc aattcaccaa
    12541 ggacacgaat acctaagcct ggtccaggga atggttggcg ccaaacgatg ctgtcaggca
    12601 tgcctaattg ggtacctaat tcacgtactt cgtctttgaa caatgtgttc aatggctcga
    12661 tcagcttgaa ttgcatgtct tcaggtaatc cacctacatt gtgatgtgat ttgatggttt
    12721 gggcagtttc agttcctgat tcgatcacat cggtataaag ggttccttgt gcaaggaaag
    12781 aaacgccttc ttcaccggca agtttggttg cttcatcatc gaagacatat acaaattcat
    12841 ttccaatgat tttacgtttt tcttctggat cagacacgcc agcaagtttt gataagaaac
    12901 gttctttggc atcgactttt ataatgttca agccaaattt tccgccaaga ctttccataa
    12961 cttgttctgc ttcaccttta cgcaacaata cgtgatcaac gaagatacat gttaattgat
    13021 cgccgatcgc tttttgtaaa agaacaccaa caacagagga atctactccg cctgaaaggc
    13081 ctaataaaac ttttttgtca ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga
    13141 agttatccat tgtccagtca ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca
    13201 agtcatttcc atattcggaa tggcgaactt ctgcatggaa ttggattccg tacattttgc
    13261 gttctgcatt ttggatcgat gcgatggggc aatctttgct ggtagcaacg acatcgaaat
    13321 cagtcggtgc ttgggtaact aggtcaccat gactcatcca aacggtttgt ttttcaggag
    13381 tgttttggaa aagggccgct tctgcagaag tgatttccaa ttctgctttt ccgtattcac
    13441 ggtttttggc tggtttaact tttccgccta atttataagt aatcaactgc ataccgtaac
    13501 agattcctaa aactgggatc cccaaatcaa aaatcttttc atcaatacca aaggccttct
    13561 catcataaac actgtttggt ccgccagaaa ggatgattcc tttagggttc attgccttta
    13621 cttcttctgc ggtaatgcgg tggctcatca actctgagaa aacaccgaac tcacgaatac
    13681 ggcgagtgat cagttggtta tactgactac cgtaatcaag tacgataatt tt
//
LOCUS       DAIGWC010000070        13188 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.071, whole genome shotgun sequence.
ACCESSION   DAIGWC010000070 DAIGWC010000000
VERSION     DAIGWC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.071"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            155..1894
                     /gene="yfcC"
                     /locus_tag="NOB74_002216"
     CDS             155..1894
                     /gene="yfcC"
                     /locus_tag="NOB74_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCI1221380.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2051..3235
                     /gene="iadA"
                     /locus_tag="NOB74_002217"
     CDS             2051..3235
                     /gene="iadA"
                     /locus_tag="NOB74_002217"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HCI1221381.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3346..3549
                     /locus_tag="NOB74_002218"
     CDS             3346..3549
                     /locus_tag="NOB74_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCI1221382.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3650..4312)
                     /locus_tag="NOB74_002219"
     CDS             complement(3650..4312)
                     /locus_tag="NOB74_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221383.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4325..5827)
                     /locus_tag="NOB74_002220"
     CDS             complement(4325..5827)
                     /locus_tag="NOB74_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1221384.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6375..8054
                     /locus_tag="NOB74_002221"
     CDS             6375..8054
                     /locus_tag="NOB74_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCI1221385.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8181..8660
                     /locus_tag="NOB74_002222"
     CDS             8181..8660
                     /locus_tag="NOB74_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HCI1221386.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8879..9559
                     /locus_tag="NOB74_002223"
     CDS             8879..9559
                     /locus_tag="NOB74_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCI1221387.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9567..10898
                     /locus_tag="NOB74_002224"
     CDS             9567..10898
                     /locus_tag="NOB74_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI1221388.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10913..11875
                     /locus_tag="NOB74_002225"
     CDS             10913..11875
                     /locus_tag="NOB74_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HCI1221389.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            11986..12324
                     /locus_tag="NOB74_002226"
     CDS             11986..12324
                     /locus_tag="NOB74_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HCI1221390.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12403..13110
                     /locus_tag="NOB74_002227"
     CDS             12403..13110
                     /locus_tag="NOB74_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HCI1221391.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT         4204 a         2324 c         2888 g         3772 t
ORIGIN      
        1 aaaataatca tacataggag aaaaaaaaca aaatagaaaa aagtgatttt ctaataaatt
       61 attcatgtgg aaatgtcatt tttactgtat aattcatttg attatccatt ttttattcat
      121 caaaattact gaaaaaagaa aggaagaaat aaatttgaag aaaacaaatt cttcaggaaa
      181 accgaaacgc gacttcacta aattatcgac accccatacg tatgtcatta tttttggtgt
      241 agtcatcttt gcatggatac tgacttttgt cgttccagca ggaaagttca gcacgcaaga
      301 tattgaatac aaagatgcaa atggcgaaac aagtactcgt actgttttac gtcaagattc
      361 cttccgttat gcttacgagc tggataagtc gtatgtgttt gatcaattag aagaactgca
      421 agatcatcca gcagaacgtg aaaaactgga tgttccggaa aaaggattgg aaaaagtcat
      481 tgctgacgga gaaaaaaatc ttacgcagga aaaactagat gaaatctcct tgacagatga
      541 tgtgctttac gatcagtacg gcgaaaatat ctatgatact tctaaaaaat tgcataaaac
      601 agccaaaata tggggaacag atgattttgg cggctttggt ttcttaaatt ttgtttttga
      661 aggactagta tctggagata agtatggatc tgctgtaggg atcgctgcat tgatccttgt
      721 tgttggaggt gcttttggta ttattatgcg taccggagcg atcgacgcag gtatctatgc
      781 gtttatcagt aaaactaagg gactggagcg tttagcttta ccgctattat tctttgcttt
      841 ttcattcggt ggcgctacat tcgggatggc agaagaggta attccattct caatggtgat
      901 ggttccattt gtcattgcgt taggatatga ctcgatcgta gcagtaaccg tgacttatgt
      961 cgcatctcaa gtcggaaatg cgacctcttg gatgagcccg tttagcgtag cggtggctca
     1021 agggattgct ggaatccccg tgttgtctgg tgcgacattc cgattgatta tgtgggtagt
     1081 tgttactgca ttagccgctg gttatatgat gatatatgca gaaaaaatcc gtaaaaaacc
     1141 agaaagttcg ttgacttaca aatcagatga ttatttccgt tctcatatca aaaagacatc
     1201 tgatgaaaat aaaaaattca tgcttgggca taaattgatc ttattagaga tgttagttgt
     1261 ccttgtctgg atcgtttggg gcgtgactca aaaaggctat tacattccag aaatcgcttc
     1321 tcaattcttt gtgatgggat tagttgctgg aatcattgct gttcttttca aattagatgg
     1381 aatgaaagtc aatgacatcg cttcttcttt ccaatctggt gcagctgatt tagctggtac
     1441 agcaatcgta gtaggtatgg ccaaagggat tcttcttgtc ttgggaggat ctgatgcatc
     1501 tgttccttca gctttgaata cgattttgca tgggatcggg acggcgttga ccggtgttcc
     1561 agctgtcatt ggtgcttggg cgatgtacat cttccaaagt ttgttcaact tggttgttac
     1621 atcaaattca ggacaagcag ctttgactat gccaatcatg gctccactgg cagatttagt
     1681 aggtgtatcc agacaagtag cagttcttgc ttatcagctt ggttcaggtt ttatggacgc
     1741 ttttacaccc gtatcagcca gcttgattgg tgtgctaggt gttgcacgga tcgaatgggc
     1801 aaaatgggca agattccaaa tcaagatgca aggattcctg tttgttttag gaactatttt
     1861 catcatgatt gccattgcaa taggtctgca gtagtactgg agacctgtaa ataaaaaagt
     1921 aatccaaaca gtagataagg actccaagaa ccgtcatttt acggtaaaat caaaggagta
     1981 aagatcctat cgtttggatt attttttaag atcctatcat cagttatact taaagaaaga
     2041 ggaaaaatgt atgaaaatca ttcgacaaat tgaagtgttt gcaccagatt acttaggaaa
     2101 aatggatgta ctgattgccg gtgggaagat tttggctgta gaagaacagc tagaaggcgg
     2161 ctacgaagga gtggaagtag aagaactttc aggtgaggga aaagtactaa ccccgggttt
     2221 cattgactgt catttccata ttttaggtgg aggaggagaa ggcggttatc aaaatcgaac
     2281 gccagaagtc acattgagcc aattgactac agctggtgta acgacagttg tcggttgttt
     2341 gggaacagac ggagaaggta gagatatgac tgcgttgatc agcaaagcga aaggtctgga
     2401 agcagaagga atctccactt atgtatacga aggttcgtac cgattgccgg taaaaacagt
     2461 aacagattct atcatcaaag actttttgac aattgataaa attatcggaa tcggagaaat
     2521 cgcagtatcc gatcaccgtt cttctcagcc aagttttgaa gagttcgctc gtgcagtagc
     2581 agatgctcgt gtaggaggca tgttatccgg aaaagctggg atcatcaatg tccacttagg
     2641 cggaggaaaa agaaagctag agctattgac acgaatcgta gaagaaacag aaattccgat
     2701 cacacaattt ttgcctactc atgcaaatcg cacaccagaa ttatttgaag cttgcgtggc
     2761 atttgccaaa cgtggtggca cgattgactt cactgctagc gaagatcctg atttttggga
     2821 gaagacagat ggtgaagttc gcttcagcaa agcactgaaa cgattgatcg aggaagatgt
     2881 ttctttagat aatttcacga tgacctcaga tggacaagga agcttgcctt attttgatga
     2941 aaacaatcat ttcctagggt taggagtagg aagtgccaag gcattgctag tagggatcaa
     3001 agaagctgtg caaaaagaaa gtatcccttt ggaaatcgcc ttacgagcta taaccagtaa
     3061 tccagcacgt atattgaaat tggataaaaa aggaaaaatc gaaattggtg ctgatgcaga
     3121 tctgtgtatc ttggataaag aaacgcttga tattgataca gttatcgcta aaggagaaat
     3181 aatggtccaa gaaaaagaag tcaaagtatg ggggactttc gaaaaaagtt tttaatcaac
     3241 agctctaact atctttttta gaaaacgagc gttctgtttg tctgtatctg ttgttgatgt
     3301 taccctgaag gtagatcaat aaacaaacta agaggaggaa gcacaatggc agatttaaaa
     3361 ggacgttcta aagatatgaa agataaagta gtcggtgaag gaaaagaagc atacggcaaa
     3421 gcaacagacg acaagagcaa agaaacagaa gggaaagcac aatcactagg tgctgacatc
     3481 aaagaaaaag ctcgaaattt aggcgacgaa gtcaaagaca agttttctcg aaaagacgaa
     3541 aaaaaataaa aaccacttat tactaattga atcaagcaaa taaaaaatcc gaaccatatc
     3601 tgcgagacag atatggttcg gattttttat ttgatcatta tcctgttttt taaacttcga
     3661 ttttttgaaa ttttttattt tttagttcaa agacttcatc acagcttttt gctacttcaa
     3721 tctcatgagt cacgatgata atacagcgat tttgttcatg ggcgatttct tggaaaagtt
     3781 tgacgatatc ttgtgaagtt gtttcatcta gatttccagt aggctcatcc gctacgatta
     3841 gttgatgttc acagcagata gcacgaacga tagcgactcg ctgctgctga cctcccgaaa
     3901 gtttggtcac ctgttttttt gctaatattt catcaattcc tacacgagcc agtcgatcta
     3961 aagcaacttg tcgataattc tcttgcttgg tcttagtgat ttccattgct gctatgacgt
     4021 tgtctagagc cgataaataa ggaagcaagt tgtaagcttg gaaaataatc gagacatcat
     4081 ttttacgata acttcttaac ccgattttgt tcagtgaacg atcttgatag tatacctttc
     4141 cttcttttgg tgcatctagt ccagaaataa gcgaaagaaa agtcgttttt ccagaaccac
     4201 ttgctcctaa aatagcgtac atttttccag cttcgaaatt cagttctaca tctttataaa
     4261 gcgcatcttg cggatcttga taccaaaatc ccaattgttc tgtccgtaac atcaaattcc
     4321 tcctttagtt taataggatt tttcttgggt ttaatcttaa tatccctata gaagctaaaa
     4381 agacagaaaa cagactgatt ccaaatgcta ctccggctaa tagtcccaat tgtgcaggtt
     4441 tgacattgat ttccaattcg ctgacttgat cagaaacagc aaatggatta ttcgtggttc
     4501 cttgttgacc atcgcgttga ccgccttgtt cttgtctgtt acctggcatt tgtccaccgc
     4561 caggagcttg ctggttttgt gtcgtggttt ctgtctgttg gtcaagtagc tgctgtccca
     4621 cggcattcgc gacgacgttt ccgctaagcg aagcaactcc taatgcaaga atcatacaaa
     4681 tagccacttc ggtaaacaat tggagaatga ttttacttct ggattctcct aaagatagca
     4741 agacgcctaa ctcatgccga cgctcccgaa tggtaatcat aatgatcaga gtaagtatga
     4801 taataccggc tacagccact agtaaaacaa catttttaga aaaacttgcc acgttgttta
     4861 aaggttccaa cattgactga tacatggaat catttgattg taagctaaat gtatctgtgt
     4921 cgatcagctt ctcagcttct ttgagaaact catccatttt atctggatca gatagagtgt
     4981 aaatagcaga atctatcgtg ttatcgtcag atgtcccatt tagttcattt gcaaaagtgt
     5041 aagaagtgta aagtgtattc gacggattca tgaagttgaa tttcataccc atactgccgc
     5101 ttgtttcgct ggattcataa attcctttga tcgtcatttc ataagtggta tcttcatctt
     5161 cagtactcgt gattgtgaaa gtatctccga ctgccaggtc atttgtttct gctagagtag
     5221 aatcaatgac tacattgttt gtgcctttgt cgctgtcatc tattccttca ccatccgtga
     5281 tttttgctgt tccatcagaa aaattactat tttgtgcagt tgctgacaca ccactgattt
     5341 gaaagtctgc ttgagtcatt tgcggattcc cgcccattcc tccagcaggt tcaccgcctg
     5401 catcagtagt ttctgaactg tcttcacttg aatcagaact agtgatggca gttattccat
     5461 cttttgccat agctgaggcg gaactttcaa aggaataact ctttacatta tctaattcag
     5521 ctattttttc cgcgtccgtt aaggaaactg gtgtaagaga aaaactgcct ggatctggac
     5581 gttcttcagt ggtagaaccg cttgaagaag tttgttcctg ttttttaaat gaagcttctc
     5641 gattggcact taaagtcact gttgctccaa cttctttttg tgcttgattc gctgcttctt
     5701 ctgcagcgct tcgaatcgtg aggccagcta gcacaaaaat aagaatggct gtgaacacgg
     5761 caaacaataa caatgaacgt ccccatttta cttttgtact tttccatgca cgtttcataa
     5821 aattcatatt ttgcatccct cctagtagat gcatttgata atagacaacc tatcttaaag
     5881 ctagcttaaa tcttatgctg tttgcacacc atcaacatga ggttctgtat atataaaaag
     5941 tcactatagt tattgcaaaa aatgtggtaa aatgaaaaaa gtatgtttca aaccgacgaa
     6001 gaagaaatga aagaggaata gcaaaagaaa tcctagatgc tacagaggga tttttacgtg
     6061 catagttgtt ctaacaattg ctgatactag cgatttagtt tatttgttgt ataataatgg
     6121 ggaacagctg aatacttata taagtattct ggctatagcg tttcgcaaaa gatccatttt
     6181 gttaatgaag tatatccaaa ataaaatgcc catccaactg tcagaacgcg gatgtgctgg
     6241 taattttcct gctgattctc cataagttga gaaatagtga ttttgcatat gcttcattgg
     6301 aatggctcat atatttagat aaagaagaaa atcgacatct ttaaacttgg atgtcataag
     6361 aagaggtgaa gtttgtgagt accattaaaa ttatcccatt aggcggcgtt cgtgaaaatg
     6421 gaaaaaacat gtatgtcgca gaagtgggcg aggatatttt tattttagat tgtgggctaa
     6481 aatatcctga aaatgagttg ttggggatcg acgtcgtaat ccctgatttt acgtatttag
     6541 aagaaaacat tgatcgtgta gctggtgtct ttttaacaca tggacatgca gatgcgatcg
     6601 gggcacttcc ttacttgttg tcaaaaattt ctgtaccagt attcgggaca gagttgacga
     6661 tcgagttagc aaaattgaat gtcagtcgta atgaagcagc caaaggattt aaggatttcc
     6721 atgtggtaga tgagcataca gaaatagact ttggtgaaac agtagtgagc tttttccgta
     6781 ccactcatac gataccagat tcagtgggga tcaatctgaa aacaaaagaa ggtagtatcg
     6841 tttatacggg agattttaaa tttgaccaaa cggctatccc aatgtatcaa acagattatg
     6901 cacgattggc ggaaatcggc aaagaaggag tcttagcctt actaagtgaa tcggcaaatg
     6961 cagaaaatcc tcagcctgta gcttctgaag cccaaatagc agatgaagta tttgatacga
     7021 tcaaatattg ggaagggcgt atcatcgtcg cttgtgtagc aagtaatttg caacgagtgc
     7081 aacaagtatt ggatgcagca gaaaaagcac aacgaaaagt tgtcttgact ggtcaagatt
     7141 tcgaacgaat tattcgcaca gcgatgcgtt tagaaaaact tcaattacca agtgaagatc
     7201 tgcttgttac gttgaaagac atgaaaaact atgatccaga agaactgatc attttagaaa
     7261 ctggccgaat gggtgaaccc atcaagtctc tgcaaaaaat ggcaaacggt acacaccgta
     7321 atgtcaagat tgaagaagga gatttggttt atatcactac tacgccaagc atcgcgatgg
     7381 aaaccatcgt ggcgaaaacg gaagatatca tttatcgagc tggtggaaca gtgaagttga
     7441 tctctgagaa tatgcgcgtt tctggccatg ccaatcctaa tgacttgcaa ttaatgatca
     7501 atttgatgaa accaacatat tttgtgccag ttcaaggaga gtatcgtgaa ttagctgctc
     7561 atgcagattt ggctcatgca gtagggatgc catacaaaaa tatctatatt actggacgcg
     7621 gagacgtgct ggaatataag aacaagcgta tgagtgttgc aggaactaca agtgcagaaa
     7681 atgtaatgat tgatggatta ggcataggtg atatcggaaa cattgtttta cgtgatcgaa
     7741 aaatcttgtc agaagacggg attttcgtag cggttgtcac tatcagtcgg cgagaaaaga
     7801 aaatcatttc aaaacctcaa attacttcac ggggattcgt ttacgtaaaa gctagccgtg
     7861 atctgatgaa agaaagcagc aatatgattg aaacaatcgt tgagaaacat ttagaaagca
     7921 atgattttga gtggagcaaa ttaaagcaag acatccgaga tcaattaggc cgttacttat
     7981 ttgaacaaac aaaacgccgc ccagtgatct tgccagtcat tatggaagct actcaacgtc
     8041 gaaataaaaa ataaacaaaa agagtaagat gaacctctct atagagtgct cgtcttgctc
     8101 tttttttgcg aaaaacaaat aatttttgaa tacagcatcc ctcgctttat aataaacgat
     8161 agaataaagg gagtgaatca atgatgagtc aaacaaaagt cgaacgttat ttagaagaac
     8221 aaaagatcag ctatcaacca cttgatttta gtcatgtggt agaagaatct ttcacagaag
     8281 aactacaaaa aagagggatt gatccagctt tgatatgtaa aactctcgta gtgaaaggaa
     8341 acaaaactgg ggtgatcatc gcattgattc ctttgaacga tcacttagat tacaaaaaaa
     8401 cgagacaagt gacgaaagat cgtaaagttg gttttcctgg aatggatttt gtattaatgc
     8461 atacaggata tccccacgga gcaaacaccc ctattggaat aaaactcgca catcctgatt
     8521 attgtttttt agcagacagt tctttaaaag aaaaagaaga agtaattgtg tcaagcggtg
     8581 aaatcgggag aagccttcgg ataaaagtag ccgatttaga aaagatcgtc catcctattt
     8641 acgctgattt aattagttaa gggacgagaa gagaagctaa gcagagcaga gacctcaaac
     8701 ttgagattat atctgcttgg tacttggtgc atcctgtatt atctgttaca attgctttgt
     8761 acatactgta ctatcaatcc aatgaaaata tatttagcag ctatattttt tcattgatgt
     8821 gcaagtgatg aaatcgtttt taataaaaaa gatacagaga aaacgcgagg tgtaaaatat
     8881 gaaaattacg tatcatggac attcctgttt aacaattgaa atggaaaatg gccaacgcgt
     8941 gatgattgac ccgtttatta caggaaatcc attgacagac ttaactgcag aagaagtaaa
     9001 gacagattgg ttgctgatta ctcatggtca tagtgaccac ataggagata tgattcctat
     9061 tgcaaaagaa aatcaagcca caattatcag tattgttgag attgctgatt atgcgaacag
     9121 cagaggagta gattcattcg gtatgaatat cggtggaaaa catgcgtttc cattcggcgt
     9181 ggtaaaattc gtacatgcac agcatagttc aagctatgaa gtagacggta tcgttcagta
     9241 tatgggcgag cctagcggaa ttattattca agcagaagga aaaacgattt atcatgcagg
     9301 ggatactgct tatttcagtg atctaggatt gcttgcagaa gaattcgata ttgatgtcgc
     9361 tttcttgccg attggcgata actatacgat ggggccagaa gatgcagcaa aggctgcgca
     9421 aacaattcgt gccaagaaag tagttccaat ccattacaat actttccctg tcattgaaca
     9481 agatcccgaa tcttttgtag agttactgga agatagtgaa ggaaaaataa tgagcgtctc
     9541 ggaaacgctg gaagtgtagg cagaaaatgg cgacaaaaca tgatttgatt ttagaatata
     9601 ttgaaagttt acctgttggc aatcgaattt ctgtaagaag catcgcaaaa gaattgaatg
     9661 tcagtgaagg aacagcgtac cgtgcaatca aagatgcaga aaatgtcgga ctagtttcaa
     9721 caattcaacg agtagggacc atccgtatcg aacgcaaatt aaaaaaacat attgaacgtt
     9781 tgacatttgg cgaggtcgtc aggatcattg aaggggacgt tttaggcggg gcggcaggat
     9841 tagacaaggt cttgaataaa ttcgtcatcg gcgcgatgac taaacatgcc atggaacgct
     9901 atattacgcc aggatcacta atgatcgtcg gcaaccgggc ggaagtccaa aaattagcat
     9961 tggaagatgg cgccgcagta ttgatcacag gaggattcaa tacgactgct gagattgcaa
    10021 agctagctga tgatcttgaa atgccgatct tacgcacctc ttatgataca tttacagtcg
    10081 caaccatgat caaccgagcg ttaagcgacc aattgatcaa aaaagatatc atgcttgtca
    10141 gtgatatcta tatgccagct gaaaagactc attatttgca gcagacagat acgatttctg
    10201 attatcagcg tttgtcagaa gaaacgcagc attcgcgttt tccagtcgtc aaccgccatc
    10261 atcgtttgat ggggattgtt acggcaaaag atgttttagg gaaatcgcca aaccagatca
    10321 tcgatcgggt gatgacgaaa gaaccaatca gtgtaaagaa aacaatgagt attgcctctg
    10381 ttagccatca aatgatctgg gatgggctag aagtcatgcc ggtcgtttcc gatgacttga
    10441 cattggaagg cttgattacc cggcaagatg taatgaaagc gatgcagctt gtccagcgac
    10501 aaccgcagat tgcagatacg atttcggatc agatatctgg aaatatccat acgattgata
    10561 ctgaccgtga aggaaatcgt ttggaaaacc ctaagttcaa attcgtagta gcaccacaaa
    10621 tggtcaatgg cgttggaacc atttcttttg gcgtacttag cgaaatcatt tctgatgtcg
    10681 cacaaaaaac aatggtgatg aaccaaaaac gaaatatctt gattgaacaa gtgaacctac
    10741 attatttgcg gctgatccaa ttggaaagcg aattagacat tcgtccacgt gtattggaaa
    10801 tcggcagacg ttccgctaaa ctggatatcg aagtgtttat tgaaaacacc atcgtttcca
    10861 aagcaatcgt tgtttgtcaa gtaatggaac gttcttagaa agcaggagtg aaatgacagt
    10921 acagcaagaa atagtagata caataaaaaa atacgataaa atcattatcc acaggcattt
    10981 gcgccctgat cctgatgcat taggatcaca agtaggatta gccgaactat tacgggaaag
    11041 tttcccagaa aaagaaatac gtcaagtagg tgaaacgatt gaagggcttc gctttttagc
    11101 agaaatgcaa gaagttgaag atgtcttcta ccaaggagcg ctagtcatcg tgactgatac
    11161 agctaattca cccagaatca gtgatcaaag atatcagttg gcagaaaaac tgatcaaaat
    11221 cgaccatcat cccaatgatg acccttatgg agatcttgtg tgggtaaata caaaagcaag
    11281 tagctgtagt gagatgattg cagaatttgc tttgatgttt cctgaatctt taaagatgaa
    11341 cgttaaggct gcacggttac tttatgcagg aatcgtcgga gatacagggc gctttttgta
    11401 tccctccacg acgtcccgta cattagagat tgcttcgata ttgagaaatt atccatttga
    11461 tgcaagtgct ttgaacagag agattgaaca aatgccgatg aaagtcgcta aactttccgg
    11521 ttatctttat caaaatatcc aggtggatga aaatggtgca ggaagaataa tccttccgca
    11581 agaaattctt gataaatatg gaatcgatga ttcagagaca gcttcgatcg tttcacttcc
    11641 tggagtgatt gacgaagtgc tggcttgggg gatttttgtt cagcagcctt cagggtatta
    11701 ccgcgtacgt ttacgttcta aggggccgat catcaatgaa ttggctaaac gccatcatgg
    11761 aggaggccat ccattagcaa gtggtgcgaa tgcaaaagat ttagcagaag tagaggaaat
    11821 ctataaagag atccaagata tatgccaatc gtataagagc agaaaaacag aatgatactt
    11881 cgttcgaaaa cgtgcctttt gtagtaaaaa tcacaaatgt atcttttcaa gatcttcttt
    11941 ttccgttaca atagtgctca ctaaagattt taaaggagaa agaagatgac attaccaaat
    12001 tgcccagaat gtggctcaga gtacacatat gaagatcgag gcttgttgat ttgcccagaa
    12061 tgcgggaacg aatggaacaa agaagaacaa gaaactgtca tagaagacgg attagtggta
    12121 ttagatgcaa atggaaaccg tctgttagag ggcgatagcg tgacagtgat taaagacttg
    12181 aaagtaaaag gtgcgtcagg tgccattaaa caaggaacaa aagtcaagaa catccgttta
    12241 gtagaaggcg atcataatat cgattgcaag gtagaaggat ttggaccgat gaaactgaaa
    12301 tcggaatttg tgaaaaagaa ttaaagaata ttcaaggtct tttcacattc ttttcctact
    12361 actaatgata aaataaagta aacgaaaagg agtgaaacga aaatgtatgg ttatggaatg
    12421 tatggttttt tagatccgac atttcttttg gtcattcttg gattagttat ttccggaatt
    12481 gcgtcagcgt acgtcaatag tactttccga aaatacgatc aagtgagaag caaaaacaat
    12541 gtgactggta cacaagcagc acaatatata ttacaaagtc aacagataaa taatgtcggt
    12601 gttcaacaaa ttgccggaga tctcacagat aactacaatt caggtaataa gatgttgagt
    12661 ttgtctcaag caactgcaca gtctacttca gttgctgcga taggtgtagc agctcatgaa
    12721 tgcggacatg cggtacaaga tgcttcgggt tatgtcccat tgaagattcg tgcagcactt
    12781 gttccagcag ctaactttgg ttcgatgatt tcgttcccct tgattatggt aggtgtattg
    12841 cttagctgga actctacgtt aatcaatatc gggattttcg ctttttcttt agcattactt
    12901 ttccaattgg tgacattacc agtcgaattt aacgcgtctc ggcgagcaat ccaaattttg
    12961 agtgaaggcg gactactgac ggaagaagaa gtaccgatgg caagacacgt attatttgca
    13021 gcagcactga cttatgttgc agcagcgctt tcgacattcc tgcagctgtt gcgcttgatc
    13081 ttattgttcg gcggcaaccg aagagattaa aataaagaag ttgtgaaatc agcgctttga
    13141 tctgagctaa taccgagagt tagctgattg aataccattt atttggaa
//
LOCUS       DAIGWC010000071        13147 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.072, whole genome shotgun sequence.
ACCESSION   DAIGWC010000071 DAIGWC010000000
VERSION     DAIGWC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.072"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(77..149)
                     /locus_tag="NOB74_002228"
     tRNA            complement(77..149)
                     /locus_tag="NOB74_002228"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="NOB74_002229"
     CDS             530..1099
                     /locus_tag="NOB74_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HCI1221392.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="NOB74_002230"
     CDS             1086..1946
                     /locus_tag="NOB74_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI1221393.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="NOB74_002231"
     CDS             2136..2840
                     /locus_tag="NOB74_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1221394.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="NOB74_002232"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="NOB74_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HCI1221395.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="NOB74_002233"
     CDS             4677..5993
                     /locus_tag="NOB74_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221396.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="NOB74_002234"
     CDS             5994..6863
                     /locus_tag="NOB74_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HCI1221397.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="NOB74_002235"
     CDS             6918..7727
                     /locus_tag="NOB74_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI1221398.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="NOB74_002236"
     CDS             complement(7830..8459)
                     /locus_tag="NOB74_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HCI1221399.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="NOB74_002237"
     CDS             8629..9921
                     /locus_tag="NOB74_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1221400.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="NOB74_002238"
     CDS             complement(9997..10659)
                     /locus_tag="NOB74_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI1221401.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="NOB74_002239"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="NOB74_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HCI1221402.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="NOB74_002240"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="NOB74_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HCI1221403.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4370 a         2265 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccattca
//
LOCUS       DAIGWC010000072        13026 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.073, whole genome shotgun sequence.
ACCESSION   DAIGWC010000072 DAIGWC010000000
VERSION     DAIGWC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.073"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            136..1059
                     /locus_tag="NOB74_002241"
     CDS             136..1059
                     /locus_tag="NOB74_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCI1221404.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFFKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            1065..2318
                     /locus_tag="NOB74_002242"
     CDS             1065..2318
                     /locus_tag="NOB74_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCI1221405.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            2452..3798
                     /gene="gor"
                     /locus_tag="NOB74_002243"
     CDS             2452..3798
                     /gene="gor"
                     /locus_tag="NOB74_002243"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HCI1221406.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(4612..5565)
                     /gene="menA"
                     /locus_tag="NOB74_002244"
     CDS             complement(4612..5565)
                     /gene="menA"
                     /locus_tag="NOB74_002244"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HCI1221407.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(5578..6681)
                     /locus_tag="NOB74_002245"
     CDS             complement(5578..6681)
                     /locus_tag="NOB74_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HCI1221408.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(6771..7727)
                     /locus_tag="NOB74_002246"
     CDS             complement(6771..7727)
                     /locus_tag="NOB74_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HCI1221409.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            8008..9942
                     /locus_tag="NOB74_002247"
     CDS             8008..9942
                     /locus_tag="NOB74_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI1221410.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            10399..10815
                     /locus_tag="NOB74_002248"
     CDS             10399..10815
                     /locus_tag="NOB74_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCI1221411.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            10829..11395
                     /locus_tag="NOB74_002249"
     CDS             10829..11395
                     /locus_tag="NOB74_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HCI1221412.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            11418..12404
                     /locus_tag="NOB74_002250"
     CDS             11418..12404
                     /locus_tag="NOB74_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCI1221413.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(12559..>13026)
                     /gene="scm"
                     /locus_tag="NOB74_002251"
     CDS             complement(12559..>13026)
                     /gene="scm"
                     /locus_tag="NOB74_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HCI1221414.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTS
                     DSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNF
                     NLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT         4062 a         2359 c         2692 g         3913 t
ORIGIN      
        1 tatttggaca gaatatatcg aactttattt tgattttttg tgaaataatt ttcaaaaatc
       61 cgactttaaa tagaagaagt attggaaagt ttttagagct atgctactat tatgaagttg
      121 taggaggaga aaattatgat cgaactcata accacagtag aaactattga acaagcagaa
      181 cagttgcttg ctgcaggtgc agatacacta tatttcggtg aagagcaatt tggattgcgt
      241 ctgcctgctt catttacacg agaagaacag cgacaattgg tagaattagc acacaagtat
      301 ggtaaaaaag cgaatattgc tgtaaatggg atcattcatc ctgaaaaaat gaaaaatgta
      361 cctgaatatt tggctttttt taaagaaata aacgtagatg tgatcacagt tggtgataca
      421 ggtattattt atacgatgaa aaaaaatcct gaattgcgta taccgtatat ttatgatgct
      481 gaaacattag taacgagcgc acgtcaaatc aatttctggg cgaaaaaagg cgcagttgga
      541 gcagtacttg ctcgtgaagt tccttttgaa gagatgaagg cgatggaaga aaaactcgat
      601 attcctgtag aaacccttgt gtatggtgct acatgcatcc atcaatccaa acgtccactg
      661 ctacagaatt actataacta tacgaaacaa gacgaacaaa aagatcgtga aagaggtctt
      721 tttatctcgg aacctaaaaa agaagagaca cattattcta tttatgaaga tagtcatggc
      781 acacatattt ttgccagcaa tgatctgaat ctctcgaatg aattgaatga actttatcag
      841 catcattact gtacatggaa attggacgga ttatttactc caggcgaaaa attcgtaaac
      901 atcactcgac tattcgccga agcaaaaaaa caaattttag aaggtagctg ggatcaagaa
      961 aaagcggaaa aaatgactag cgaaatcagt aaattgcatc ctgaaaaccg tgaattagat
     1021 acaggattct tttatattga tccttctgct atcaaataag gagtatgatg aaagaaatga
     1081 cagtaaaaag aaaattgaaa cgaccagaaa tcctagcgcc agcaggaaca ctggaaaagt
     1141 taaaaaccgc gatccattat ggagcagatg cagtatatat tggcgggaat gcatatggtt
     1201 taagaagccg tgcaggtaat tttacttatg aagaaatggc tgaaggagtt gcttttgcaa
     1261 aagaacatga tgcgaaggta tacgttgctg ctaatatggt cacccatgaa ggaaatgaag
     1321 atggagcagg ggaatttttc cgcagtttgc gtgatgtcgg tatttctgca gtgattgttt
     1381 ctgatccagc tttgatcgaa atttgtgcga cagaagcccc aggtctgccg atccatttat
     1441 ccactcaagc ttcagcaact aattttgaga cattggaatt ctggaaagaa gaagggttgg
     1501 aacgtgtcgt tttagctcgt gaagtttcaa tggaggaagt ggcagagatt cgtaaaaata
     1561 cggataccga aatcgaagca tttatccatg gtgccatgtg tatctcttat tctggtcgat
     1621 gcacattgtc caaccatatg tcgatgcggg atgcaaaccg tggcggatgt tctcaatctt
     1681 gtcgctggaa gtatggattg ttcgatatgc cttttggtca agaacgaaac agtttaactg
     1741 atacaggcga agtggaagaa gaattctcga tgagtgcagt ggatatgtca atgatcgaac
     1801 atattccaga attgattgaa aacggcgtag acagcttcaa gatcgaagga agaatgaaat
     1861 cgatccatta tgtatctacg gtgtcaaatg tctataaagc ggctgtagac agttatatgg
     1921 aagatcctga aaactatgtc tgcaagcaag aatggatcga cgagttatgg aaagtagcac
     1981 aacgagaatt agctacaggt ttttactaca atacaccaac tgaaaacgaa caattattcg
     2041 gtgaacgtcg taaaatccca gtatataaat ttgtcggtga agtattatct tatgatgagg
     2101 caacacagat tgctacgata cgtcagagaa acttgttttc tgtaggagat gaaatcgaat
     2161 tttatggtcc aggattcagt catttcagtc aaaccgttga agttatgcat aatgaagaag
     2221 gcgaatccat tgaccgagca ccaaatccaa tgatgatttt aactatgcca gtcgcacagc
     2281 cggtgaaacc tggagatatg atccgaaaac gtaaataagg aaaaagctga tatatccctg
     2341 ttttaagcat cttcgcatac aaaattcaag aaaagtgtta cacttgtttt ctgtagaaaa
     2401 aggatcgtta aataaaggtt ttgattgatc tcttcaataa ggaggaacaa aatgcaaata
     2461 tatgattaca tcgtaattgg tggcggctct ggcggtattg cttcagcaaa cagagcaggg
     2521 atgcatggcg caaaagtttt gctgattgaa gcgaatgaat tgggcggaac atgtgtcaac
     2581 gtcggttgtg tacctaaaaa agttatgtgg caagcaagta cgattttgga aacaattgaa
     2641 cgagatgcct caagttacgg tatccaagca gatttaaaaa atgttgattt cgccggtcta
     2701 gtagaaagac gagaaaaata tattgatttt ctacacggtg cttatcaaag aggattagat
     2761 agcaatcatg tcgaggctat aaaaggttac gctactttta tcgatagtca aacgatcgaa
     2821 gtaaacggtg aaacctatcg tgctcctaaa atcttgatcg ctactggagg ccgtgcaagt
     2881 aaaatgacca ttcctggtgg agaatacgca attgattcaa atggattttt tgaattaaca
     2941 gagttaccta agagagcaat cgttttaggt gctggataca ttgcggctga actttcaggt
     3001 gtatttcgtg gtttaggtag tgaagtcatg tgggcatatc gaaaagaacg accacttaga
     3061 acgtttgata aaatgctttc ggacaatttg atccaaatgt accaagaagc tggaataaaa
     3121 acttacgcac atcatattgc taaagaaatt actaaaaaca atgacgaata tacggtgcta
     3181 tttgaaaatg gtgaaacctt aactggtgat tgtgtacttt ttgccggtgg acgtgtaccg
     3241 aataccgaaa aattaggtct ggaaaataca aatgtggaat tggacaaaaa agggtttatc
     3301 aaagtagata aataccaaaa tacaacggat gaacatattt ttgctgttgg tgatgtgatc
     3361 ggtaaattag atctgactcc tgttgcaatc gcagctggta gacgtttatc agaacgttta
     3421 tttaatggaa agaaagattc ttatcttgac tataaacttg ttccgacagt cgtctttacg
     3481 catccaccaa ttgcaacaat tggtttgaca gaagaagaag cattggaaaa atatggcgaa
     3541 aatgaattga aagtttatcg ttcacgcttt accccaatgt actttgcatt aaatgattat
     3601 cgccaaaaat gcgaaatgaa attgatctgt gtcggaaaag aagaaagaat cgtcggctta
     3661 catgctattg gtgttggtgt cgatgagatg ctgcaaggtt ttgccgtggc tatcaagatg
     3721 ggtgcaacta aagaagactt tgacaataca gtagccatcc atccaacagg agcggaagaa
     3781 ttcgtaacga tgcgataatt taatattaac agttccaaca gctttttatt gaacaaacca
     3841 tgtaaaacca gaaaatcagt atactgattt tctggttttt tgttttttag ttatttatgt
     3901 aagattgctt cgataattct caaaacgaaa taagtaggga agttggagat tttgattatc
     3961 ttcgtaactg acgaagagta aatgaatcca tttggtatgc actcttaagt tcaaaatatt
     4021 ggtatcgatg tttaaaagaa atagaaatgt atcgaagaac agatgtttaa aaaagtgtga
     4081 ctttgtataa ataaattaga agaagcaaac gaggatgtta aaagaatacc atatagttac
     4141 caaaccaaga aagttctcgt caagttcgct ggtacgaatc aaatcaagtg aaaaaaggga
     4201 ctgtgaaaaa aattgtgtca tagttagtca ctttttccga acaaatagtg ttcaatcagc
     4261 tgtccttcgg tattagctca aaaaacggca aaatatgagg aactattttt ccatttgttt
     4321 ctctaatact caggacaaaa cactgatttt acaacctctg ataaacggtg ttcaaaagcc
     4381 agtttctcgg tattaagcca aatttatgca aaaatgtgga aagccatttt cacaaaattt
     4441 ttcttaatac tcgaaactaa gcgacttttt cacaacctcc tgataaacgg tgttcaaaag
     4501 cttgcatctg cggtaataag cccaaccaaa cgaaaaatat aaggagctat ttttatttgg
     4561 ctgttcttat tacttgatgc agggcagttt tttcacaacc tcttcatgct gttaaatggc
     4621 ttgcataatg attgttagta atagccccaa tacataactg gcattgaata agaccatatt
     4681 tttgatggaa tagctgaaac tgataggctg gggtaacgtt tgcttgaatt gatccaaatg
     4741 cttcttcaca attggcaagg tcaagaaggt gaccaagatc ggccattcat agataccgct
     4801 caacaacccc attaaaatca cgaaatagca agcatacatc aatagctgga ataagactgt
     4861 tcccgcagga cgtccgatat aaaaaactag tgtatagcga tgattttcaa tatcacggtc
     4921 aagatcccgc aaattattag ccaacatgat attggcaatc gtaaacacca agggtaagga
     4981 agctaatacg attgctgcta tagcccaaag atttcctacc aaagcaaatt gtccagatga
     5041 aaagttgact gtcagatcat agacatctga accgaatgta ttgacataaa cgaccatggc
     5101 aaaaattcca aggcccatag tcaccccact gaaaatttcc cctaaaggca ttcgagataa
     5161 aggaatcggt ccgaatgtat agaatactcc aataaaacaa cagataaatc ccatcaaaag
     5221 taaaagccaa cccgtattga tcgttagaat aacgccgata acaaaaacaa atgcaatcat
     5281 agctaaaatc atgtttcgaa tcaatacagg agatagattt ctgcggccaa tgacattttc
     5341 ttcatactta tatacttcag aatgagcctt ttcataatcc atgtaattat tgatagcggt
     5401 agtcgctaaa tcaaaaacta gcattccaat aaaaaataaa aaagtgttta gccaatgtat
     5461 ctcatgaaaa aaagcgatag agaataatac ccctaccgca aaaggaaata cactagccac
     5521 ctttgttcgt atttcaacta cttctaaaaa gatttttagt gtcatggttc gtactcctta
     5581 ttttagttca gaacggtcac ccatcgtgta atgggagtcc tccgataatt tgaaggtgtc
     5641 tttgattgga tcggtcacat atactttatc gtcttttgtc acgaagatcg cttccgtccc
     5701 gttattcaat tcgctttcga cgtattccag tccttttttc acacccattg aaaagactgc
     5761 tgtagacaac ccgtcaccat caattgattt atctgttatg atcgtgacac ttgcgatatc
     5821 attgtcgaac ggataacccg tttttggatc aaacaaatga tggtattttt tgccatctac
     5881 ttctaaataa cgctcgtaaa ttccagaggt aactaatgtt ttgttccgtt ctttaataga
     5941 acctaaaaca gatccgcgag ccatgttcgg atcttggatg ccgactgtcc agtcttggtt
     6001 ttcgcctctt gggctgtggc ctaagacata gacattaccg cccaagtcaa cgatggcagt
     6061 ggtcactcct tgttttttca agactttcac tacttcgtcc gtaatgtaac ctttggcgat
     6121 tgcacctaaa tcgatgatca ttcctttttc ttttagataa acagtttttt ctttgtcatt
     6181 tagttcgatc ttatgataat ccactaattt caatgcctga tcgatttctt cttgggaagg
     6241 ttttctggcg tcatcaaaac cgattcgcca taattgtgtg attgcaccaa tcgccatatc
     6301 gaatccgcct tgagaatctt ggctatattc gtaggcccgc ttgactaacg tgtagacgtc
     6361 atcagaaact tttactggtt tgatcccagc ttgctcattc acttcatcga tctcagaacc
     6421 tttttgattg atcgtgattt tatcaccaag ttcttttact cgatcgaagg caggtttcaa
     6481 tgctgattct ttgccttcat catacacacg gatacgaacg taagtcccta acaagaactg
     6541 ttcatcagaa tatggatctt tcaatatctt ggtagctgct gaactttcag tggttgtttt
     6601 atttgctgag ttgctgcagc cagttagcac cataaaagag atgcccagtg tgattaagga
     6661 aaatagtagt tttttccgca tctttttcct ctcttcattt tgaaaggtga gacgactgcc
     6721 taatctggct atcgtcccac cctccaactt ttattagtat gattatgtga ttatttttct
     6781 gttacgatat tatctacttc gattgtttga gtgtcgcctt tttcagctgc attcactaat
     6841 tgttgtgcgt acatgatgaa tgaatgtgag ctgtgtgtag cacctgtaac aacttctaca
     6901 ttagcaggtg agccatcttc ttcgcccatt gctttgacga attcgtcgtt cagagtaggg
     6961 atgtaagttt ttggttctgt accgcttttt gctttcatat tttcattata ttctgtatca
     7021 tcttgttttg atttaccgtc tttgtcgata taatcaaagt ttgattcagt tactttgccg
     7081 ccagcaactg tcatttcgaa ttgcacacgg tagccgttag agtagttctt ttcttcaagc
     7141 ttgtaagtgc cgtctttcaa atcagcacca ttgtcgattt cgattgtatc tgtgttacca
     7201 gcttgagcag cttggatcaa ttgttgtgcg tagttttgga agctttcaga tgagtgagta
     7261 gctccagtta cgacttccac accgcttgcg ctttgtgctt ttaagaattg gtcattcaac
     7321 tcaggaatgt atttttctgg gtttgtgcca gattttgctt ccatgttttt gttgtattct
     7381 gcatcttttg tttttgattc gccgttttca ttgacgttat catattttga ttcagtgatt
     7441 ttgccgtctt ttacaaccat ttcaaagact gcacggtaac catttgaata atttttttct
     7501 tctaatttat atgtgccgtc ttgcaaatct ccgccagcta caacttttgc agatgattct
     7561 gttgtgcttt ttgcagtcga agattgtgct gtagatgatt cagaagaaga gtttgagctt
     7621 ccgttgtcat ctgcgccgca agcgcctaac actagagctg aaaatgctaa tacggcaaat
     7681 ccagttacaa aacgtttttt cttcatttta ataccccacc attccatttc tagtccacaa
     7741 tttttctttg tgattcatta tacattctaa tctttttagc ctataagtca actatttttg
     7801 ataaataacc catgtaatat ttcaaacgtt ttctttcagc aaatttcgtg aaaaaacgct
     7861 ttattttaaa atttgaaaaa aatccaaaag gagttagaca aaagaacaga acatctatat
     7921 aatatatgga gattgtgtaa taagtatcaa actaaaagaa ttatcatata ttcattatat
     7981 agatagtcta taaggagcgg atgatcaatg gcaaagcaaa atattgtcgt tgtaggagca
     8041 ggatatgccg gtgtttcagc tacaaaatac ttggcaaaga aactgaaaaa agaagatgta
     8101 gcaattactc tgatcgatcg tcattcgtac catactatga tgaccgagtt gcatgaagta
     8161 gctggcggac gtgtagaacc agaagcaatc caatacgatc tgcagcattt gtttgctcgt
     8221 caaaagaatg tacaacttgt cacagacact gtaatcggta tcgataaaga acgaaaaatc
     8281 gtcaagacca aattaggttc ctatcctttt gatcagctga tccttggaat gggcggagag
     8341 ccgaatgact ttggtacacc tggtgtcaaa gcacacggat tcaccctttg gtcatttgaa
     8401 gattctgtaa ggattcggga acatattgag aagacagtag caaaagctgc attggaacca
     8461 gatgatgaac tgcgtaaagc catgctgact ttcgttgtct gtggttctgg atttaccggt
     8521 attgaaatga ttggggaact gatcgactgg aaaaatcgcc tagccaaaga ttataaatta
     8581 gatccaaacg aaatcacact gatggtcgta gaggcaatgc cgacgatctt gaatatgttg
     8641 gatcgaaatg atgctgcaaa agctgaacgc tatttgcgta agcacaacgt ggaattatta
     8701 ttgaatgcac caatcgtaga agtggctgct gatcatatca aattgaaaga cggacgcaac
     8761 attccgactc acacactgat ttggacagct ggtgtcaaag gaacttctga cgctgctgac
     8821 tttggattag aatcagcacg cggacagcgg ttgatcgcca atgaatatat gcaggcaaaa
     8881 ggctacgaag ataaaaacat ctatatcatt ggtgatttag tcttttatga agaattccca
     8941 ggaacaccga caccgcagat cgttcaagct gctgaacaaa caggacacac agccgcagcg
     9001 aatatcgtgg cttcgatcaa aggcggagaa aagcataaat ttaaaggaaa ctatcaagga
     9061 tttatggttt ctattggtgc caaatggggg gtagctaacc tatttgataa gatccattta
     9121 agcggatttt tagctatcgt aatgaaacat atcgtgaatt tgaaatactt ctttgatatt
     9181 cgttctggtt attatatgtt ccaatattta atgcatgagt ttttccatat caaagatgat
     9241 cgcaacgtga ctcgaggaca ttcttctcgt tacggcaatg tcttatggag tgtgccactt
     9301 cgtattttct atggtttagt ttggttcgtt gaagcttcca aaaaaatcat tgggaatggt
     9361 gaagtgttca aaccaagtac ttggtttggt gaaggatcat ggttcactgg aaacagtgtg
     9421 ttcccttgga catgggaata caatgtaaca gatgttgcca gtggtgcttc tgctgctggt
     9481 gatgcaacca cagctgccag cggagcaggg gcaagtgccg gagaagcagc gactcaagct
     9541 gcacattttg gtttgagtta tgcatacggt gaagaaccaa tggctgtgat tgagaagtca
     9601 ccagactggt tcacaaagat catgcaagtg atcatgccaa acaatgatgt agcaatgttc
     9661 ttccaaaaat tcatggtatt ctttgaaatt gccttggcat tagcattgat tgctggatta
     9721 ttcacatggc tatgcagtgc gacaacgatt gtattggtga tcacgttctg cttatcaggc
     9781 atgttttact gggtaaacat ttggttcatt tttgttgctt tcgcattgat gaacggttcc
     9841 ggacgtgcga ttgggttgga tcgctgggta attccatggc tacaacgtac actaggtaat
     9901 tggtggtacg gtagaccaag ttcccagtac ggcaagaaat aaatagataa agaacgttat
     9961 ttgaatgcaa gatttcaata gaaaggggct gagacaaacc gtcacagcct cctttttatg
    10021 taaaattaaa ggaataagat gcccgagata agcctccatg agcaagacac aggtgtcaca
    10081 acctctgtta caacctcttg ttataaacgg tgttccagaa gtagcttctt cgaaaaataa
    10141 gccgaaattt cacaaaaact tgaaaagtaa ttttcgtaaa ttccttctta tttcttgaag
    10201 ttgcccactt ctgtcacaac ctcttgttat aaacggtgtt ccacctgctg cttctcggta
    10261 ataagcccaa agaattagaa aacatggaaa gctgttttct attcttcgtt cttattactc
    10321 aaagcaagac acaggtgtca caacctcttg tttttatgct aaaattgggt gagttaatct
    10381 ggaaaaagga gaacaaaaat gagccttaaa gaatttgctg aaaaaagtct gctcaaacct
    10441 tgggatgttt ttattatttt gcttttgact gttctttctt ttttaccagt catgattttt
    10501 ggtcttcagc aaaacaccgc aacagcagaa aaagaagcgg tactgcgtgt ggatggcaca
    10561 gaaatcaaaa cattcccttt gatggctgga gaagagagca acacatatac ttacaaagat
    10621 gaacacggag attataactt gatcgagata gatggcgatc gagtacggat aaaagaagca
    10681 gattgcgatg accagatctg cgtacgtcga ggctgggcaa cgaaaaatgg cgaaaccatc
    10741 gtctgtttgc cacataaatt agtgatcgaa gtccgttcaa cagatggagg tgacgaagac
    10801 agtctgattt attagacctt tacacaccat gagtaaatta caaaaaatga tttatatttc
    10861 gctacttgtt gcacaaggag tgatcattgg tttattggaa aatatgatcc cttatccttt
    10921 ttcttttgcg cctggtgcaa aactaggctt agccaatcta atcacgatcg ttgccatttt
    10981 taccatgaaa aaacaagaca gcttcttact actttggcta cgactattcc tgactacttt
    11041 gctaggcgga acgatttcca cattccttta tagtatgagt ggtgctttgc ttagttattt
    11101 tggaatgtta ttggtcaagc aattaggacc aaaacgtgtc agtatcatcg gaattagtgc
    11161 ggccggcggt ttcatgcata atgtcggaca gcttttgatg gcttctttca ttgcacaatc
    11221 atggacagtc atgttgtact tgccagtcct ttcagtttta gggattttat cagggattgc
    11281 aatcgggatc gcagcgaatt atcttttacg acatgtgcag acacttcaac gattccaaaa
    11341 agattatgag cagggaacca aacaaaaatg gagcccaatg tttaccaaaa aataatcgtc
    11401 acacaaggag tttttttatg aagctacatc caatgtggga aaactatcct gctttaagta
    11461 aagaattgac agaaacacta aaacggatgg aagaaactgt ccgcctgaaa aacaaacctg
    11521 tcgaacaagc aatcaaagaa acgatccatg ccggcggaaa gctgttgcgt cctgcctatc
    11581 agctattgtt ctcacaattt ggaccagagc aagatcgaga caaagccatc gctttggcag
    11641 cttctatcga aatgctccat acggccacac tgatccatga tgatatcgtt gatgaagcgg
    11701 atctgcgacg tggtcagcct aatatccgta gtcagtttgg taatgtcgtt tctgtctatg
    11761 caggagacta tttatttgtc tgctgtttta aactattgtc tgattactcc acttccttga
    11821 aaagtctcca attgaattct cgcagtatgg aaaaagtatt gaatggcgaa ttagggcaga
    11881 tggatgatcg ctataattat gaactttctg taaaagaata tttggaaaat atttcaggta
    11941 agacagctga actgttccaa ttaagttgtt ctgttggcgc ttttgaaagt ggaacaagcg
    12001 agcgcttcgc aaaaaaagca ggagatatcg gactttctat cgggatggcc tttcagatta
    12061 tcgatgatat tttagattat acaaaagaga gccaggaaat cggcaaacct gtactagaag
    12121 acatgcgtca aggggtctat tctttaccgt tgatctactc tttgcaaaaa aacaaaccaa
    12181 agctactacc ttatttagag aagaaagcgg caatgacaga agaagatgtc gacgccgtac
    12241 gcaaaatcgt tgaacataca ggaggcgtgg aagaagctag gaagttagcg gcctcttaca
    12301 cagaaaaggc tttgaaggaa ataaagaaat tacctgccac ctctcttcga acaaaagaga
    12361 atctcttttc ccttacccaa ctgattttgg atcgcaaaga ctgaataggg aaaggttcga
    12421 tacgtaaata aatttctcag aaggaaatct acgtgttttt tgacaaattg aattgtagtt
    12481 cttgtattta tgataaaaag caaaaataaa gagcaacgtc cgttagcgac gttgctcttt
    12541 tttatcttga atattttttt accttttcga tttcttataa ctcataaaag tgattcttaa
    12601 accgattaca agtaatataa cgcctgcgag tgttatccaa ttattcgatt gacttccagt
    12661 tttaggaagt gctctttttg atttgtttcc attgtcattg cttgttttat tagttaagtt
    12721 aaagttcgtc ctgttatccg aacttgtttt tgagaaggag acacttgcat gacgtgtatc
    12781 gcttgtggta gacgacgtgt ctgtactatc gcttgaagtt gatgaatctg agctatcact
    12841 tgtggtagag gatgtatctg tactgtcact tgaagctgac gtgtccgtgc tatcacttgt
    12901 agtggtagat gaatctgagc tatcacttgt ggtagaggta gtatctgtac tgtcacttga
    12961 agctgacgtg tccgtgctat cacttgtggt agaggtagta tctgtactgt cacttgaagc
    13021 tgatgt
//
LOCUS       DAIGWC010000073        12900 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.074, whole genome shotgun sequence.
ACCESSION   DAIGWC010000073 DAIGWC010000000
VERSION     DAIGWC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.074"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(116..1564)
                     /gene="cls"
                     /locus_tag="NOB74_002252"
     CDS             complement(116..1564)
                     /gene="cls"
                     /locus_tag="NOB74_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCI1221415.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1716..2609)
                     /locus_tag="NOB74_002253"
     CDS             complement(1716..2609)
                     /locus_tag="NOB74_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1221416.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2593..3279)
                     /gene="ftsE"
                     /locus_tag="NOB74_002254"
     CDS             complement(2593..3279)
                     /gene="ftsE"
                     /locus_tag="NOB74_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HCI1221417.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3384..4485)
                     /gene="prfB"
                     /locus_tag="NOB74_002255"
     CDS             complement(join(3384..4412,4414..4485))
                     /gene="prfB"
                     /locus_tag="NOB74_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HCI1221418.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4611..7145)
                     /gene="secA"
                     /locus_tag="NOB74_002256"
     CDS             complement(4611..7145)
                     /gene="secA"
                     /locus_tag="NOB74_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HCI1221419.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            complement(7367..7918)
                     /gene="raiA"
                     /locus_tag="NOB74_002257"
     CDS             complement(7367..7918)
                     /gene="raiA"
                     /locus_tag="NOB74_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HCI1221420.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(8046..8765)
                     /locus_tag="NOB74_002258"
     CDS             complement(8046..8765)
                     /locus_tag="NOB74_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HCI1221421.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            complement(8762..10075)
                     /locus_tag="NOB74_002259"
     CDS             complement(8762..10075)
                     /locus_tag="NOB74_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI1221422.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            complement(10156..10476)
                     /locus_tag="NOB74_002260"
     CDS             complement(10156..10476)
                     /locus_tag="NOB74_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1221423.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            complement(10584..10871)
                     /locus_tag="NOB74_002261"
     CDS             complement(10584..10871)
                     /locus_tag="NOB74_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221424.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            10998..11642
                     /locus_tag="NOB74_002262"
     CDS             10998..11642
                     /locus_tag="NOB74_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HCI1221425.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            complement(11701..12408)
                     /locus_tag="NOB74_002263"
     CDS             complement(11701..12408)
                     /locus_tag="NOB74_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1221426.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(12628..12798)
                     /locus_tag="NOB74_002264"
     CDS             complement(12628..12798)
                     /locus_tag="NOB74_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221427.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
BASE COUNT         3565 a         2797 c         2243 g         4295 t
ORIGIN      
        1 taatttcgct catgcgagac gctttctcca tttctgacgt actctcagaa atggccccgt
       61 tagaaaagga cacgagatct ccatctgttg atggttctca tgtccttttt atgttttaaa
      121 ggagcggcga aatcaatctt gctaatcctt ctttcatctt gatgattatt cctcggtttt
      181 catacatttc ttttgtgaga tgcgtagaaa ttttcgagtc ttcaaaaaaa gcttttctta
      241 cacgtgaagc cattcgttca tcataaacca gtgtattgac ctcaaagtcc aagcgaaatg
      301 aacgaacatc gatatttgct gagccaactg aaacaatgcc accatcgata atcatcgtct
      361 ttgcatgaat aaatccattc tcatatgttt cgatccttgc tccatactcg atcagctctg
      421 cagcgaaaga atacgttgcc cagtaaacga gaagatgatc tggtttgtta ggtatttgga
      481 tatgaacttt tacgcctgaa agaagagcca acttcagtgc ttcatgaatc gatccatccg
      541 gtatgtaata aggcgtttgg atcaatatct cccgtttggc taacgaaatc attttcaaat
      601 aagtcatttt gatttgttca tgttcggtat ctggtccgct tgtcacgatt tgaacagcta
      661 tatcaccagt agtgtgaatg gacggaaaaa atttgggaga atagcctact tcttttgtat
      721 gctgagaatt ccagtccatc aaaaaacggt tttgcaaggt atacaccgct tctccgtaaa
      781 tacgcaaatg attgtctcgc caataaccaa atttctttac caatcctaga tattcatttc
      841 caacattgaa cccacctgta tatccgattt tcccatcaat aactacgatt ttacgatgat
      901 tgcgataatt gatccgagga ttaatatacg gaacaaatag aggaaagaaa aatgcgactt
      961 ctccgcctgc ttttttcaaa ttctgaaaaa agctggaaga aacttgtgtg gaaccccatg
     1021 catcaagaag gactctgact tttacccctc gtcttgccgc ctctgtcaat gcatctcgaa
     1081 cttcttcacc taatgcatca ctgcgataaa tataatactg gaagtggata tggtcttctg
     1141 cctgcttgat atcttcaatc agcgcatcga atttttcacg accatctgta aataaagtga
     1201 tttcattttt agtcgtatag agcgtacttt caaataccgt gagcatatag atcaattgtt
     1261 tcacatctac ttgtccagta ggcggatgag gataaagccc tcgcatcaat gcctgtttgt
     1321 cttcttcaat ttccaggttc ttaccgattt tcccttggat cttcaaatca aagattttct
     1381 ctttggaaat ccctcttcct aaaaaaatat ataaaataaa tcctacaact ggaatgaaca
     1441 tcaaaacgag cagccatgcc catgtttgag cagtttcctt tctttctcga aaaacgatga
     1501 taaaggaaag caaaatattc ataatcaaaa ggatcgtaaa aaaattgtca acgataattt
     1561 tcacggcttc acctcttctt ctaccaactt aagaataccc aagttgtttt ttaaagtaaa
     1621 gggaaaaaag ccgcttcctt ctattctcct agccaataaa aaaagaaagc tggaacgaaa
     1681 ctgtccaact ttctcatttt atttatattg tggtattaga atttcaagaa acgtctcata
     1741 gaaatgatcg agccaagtga accaatgatc acaccaatgc cgaccattaa aagattgatt
     1801 ttccaaacga tattttgtgg atgaatcaat gaataatggg aacgtaataa tgatggattg
     1861 atcaattgga aaaaccatgc ataaccaaat gtgatgatca aaatcggaag aatcgcaccg
     1921 atcagaccga tccagccacc ttcaaggaaa aacggccagc gaatatatcc attttttgca
     1981 ccgactaaac gcatgatttg aatttcacgc tgtctagaca aaatcgtgat ccgaatcgtg
     2041 ttcgaaatga gaaacatcgc tacgaacagc agcaatgccg ctgcaactaa tccccatgtc
     2101 cgaactgcac cagcgatttg gaaaatccga tctgaggaag ctccaccgta atcagaacga
     2161 gaaacattct tcaaatctgc tgcttcttct gctacttgtt ttgtataaga aggatcagta
     2221 gcacttacta catacacatc atataacggg ttattgtcac cttcaaacaa tttccaggaa
     2281 tcacccattt cgttttggat ttttttcaat tcctgttctt tgcttgaaaa ttcaactttt
     2341 ttaacatgat ctaagtcatt caattctttt tctagctttt tcatctcttc gtcttttgta
     2401 ccgatatcta cgaatacaga tacatcaacg tttccttcta tatcctgagc taatttagtt
     2461 gcattcatga taactgccat gaatacaccg actaaagtca acgtgatcgt taccgcactg
     2521 actgaagcaa ctgtcatcca gccgttacgt ttcaaactct tgatactttc taataaatgg
     2581 cggaaaaagg ttctaatcat cgtatccata ttccccttcc gcttgatctc gaataatgcg
     2641 gccgttttcg atagcaatta ctcggtgccg aatcgtattt acgatcgtac tgttatgtgt
     2701 agccatcacg acagtagttc cttgggcatt gatccgatct aataatttca tgatttccca
     2761 tgagttttct ggatccagat ttcctgtcgg ttcatccgcg ataagtactt taggcgtatt
     2821 cacgattgcc cgagcaatag agacacgttg ctgttcccca ccggataatt cgctaggaaa
     2881 gactcgaact ttgtgtttca aaccaacaag gtccagcact tccattactc gttttttgat
     2941 atctcgaggt tttctgccga taacttgcat agcgtacgca acattttcat atactgtttt
     3001 tcttggtaat aatttatagt cttggaacac cacgccgatt tctctgcgta gataaggaac
     3061 ttcgcggttt ttgattgcta ttagatcatg acctgcgacg ttcaaagttc cttttgaagc
     3121 tttttcttct cgatacatca atttgatgaa tgtagattta ccggctccag acggaccaac
     3181 cacatagaca aactctcctt gttcgatgac aatcgagaga ttgcggatag cggtcgtacc
     3241 atttgagtac ttcttcatta catccttcat ttcaatcatg gcgttctctc catatctttt
     3301 tcagtcttta gctattatag catggcaatg tttcaacatg cttgcaaaat cttacaattt
     3361 tatttcaatt taacaatgag ttcttattgt agatgcattt ttaaatagcc gtcaataaat
     3421 aaatcaaggt caccgtccat aactgcttgg acatttcctg tctctacgtt tgtccgatgg
     3481 tcttttacca tagaataggg atggaaaaca taagaacgga tctgtgaacc ccagccgatt
     3541 tctttttgtt ctcctcgaag tgcagctgct tcttgttctt tcttttccac ttctaattga
     3601 taaagcttag cttttaacat ccccatcgct tgctcacggt ttttcaattg tgagcgttgt
     3661 gcctgactag ctactactgt tcctgtaggc aagtgagtga tccgtacagc agattctgtt
     3721 ttattgatgt gctgaccacc tgcaccactt gctcggtacg tatcgatttt caaatcatct
     3781 ggattgattt ctatatcgat cgtttcatca agctctggca tcacatctac cgaacaaaaa
     3841 gaagtatgac gtcgtttcgc tgagtcaaaa ggcgaaatcc gtacaaggcg atgaacacct
     3901 ttttctgatt ttagataacc aaaagcgtta tgtcctttaa tcagcagggt cacactcttg
     3961 atccctgctt catcacctgc ttgataatct agtgtttcta cttgatagcc atgctgctct
     4021 gcccaacgtg tatacatacg taaaagcatg ctgccccagt cttgggactc cgttccgcca
     4081 gcccctggat gcaattcgac gatcgcattg tttcgatcat aaggtccgtc taacagcata
     4141 gataattcat acgtcttcat tttttcatct aatgcattga tacgtgtttc tgcttcttct
     4201 tgcattgctg catcaggttc ttcttgcagc atctccacca tcaattcgat ttcttctagt
     4261 tcttcggcaa gagaatggaa ttggtcatag gtttctttat tagcgttatt ttcgctgatc
     4321 actttttgtg cggcttcgct gtcatcccaa aaaccaggtt cagccatttt tgcttctgct
     4381 tccgcgatgt cttcttccag ctgatctaag tcaaagagac ctcctgaaac ttgtgacctt
     4441 ttcctgcatt tctgtcagga gatttcgaat ttcggatatt tccatgtttt ttccttcttt
     4501 cactatactt ttttcattat atctagtcta acagaatcag caaataacag aaagaaggtg
     4561 agacgaattc ttaaaaaaag aatttgtctc accaatcctg ctgtcagaaa ttagtttgca
     4621 ttttttccat gacagttctt atattttttc ccgcttccac aaggacaagg atcatttctt
     4681 ccgaccttgt tcacatggat tggctgtttt ttcgcgctag tattactatt ttctttggca
     4741 tctccgtctt ctgagtgaga agctgttcct tgagaaacct gttcacgctg tacgttttga
     4801 cggatctcag ctttcataaa gattcgagtg acttcatact cgatggcgcc taccatatct
     4861 tcaaacatct tatagccttc tgtttgatat tcgactaatg gattgttctg tccataagca
     4921 cgtaagccga ttgactgacg taattgatcc attgcatcaa tatggtctgt ccatttagag
     4981 tccacaacac gcaagatcac gactttttca aattccaaca gttgctctgg accatttagt
     5041 tgagccgctt tggtattaaa tacttcttgt gctcgttcgt ttagatactc tttgatctcc
     5101 tgagatgttt ttccttcgat atctgcaaga gtaatactat cttcatggac aagagtactg
     5161 ccggcaaaat cgatgatact ttccaaattc caattttctt tctctaattg tgtatgcgca
     5221 tctactacac gactgattgt ccgtttgacc atgttcatta gtggcttgga taagcttttt
     5281 tcttccatga ttacttcttg tcgctgttta tagattactt cacgttgttc acgcatcaca
     5341 tcatcgtatt gtaagacgtt tttacgtgtg tcatagttat ttccttctac acgtttttgt
     5401 gcagattcta cttgtttcgt cagcatcttg ctttggataa cagcatcttc ctcaccgatc
     5461 ttcatccgat ctaagaaagc tttgattcgt tctgaaccga atcgtttcat caaatcatct
     5521 tccaatgaca agtagaattg tgacatacca gggtctcctt gacgtcctgc acgtcctcga
     5581 agctggttat cgatacgacg agattcatgt cgttctgtcc cgataactgc tagaccacca
     5641 agttctctta ccccaagtcc taacttgata tctgttcccc gaccagccat gttggtagca
     5701 atcgtcacag cacctttttg accagcattc atgatgatct ctgcttcttt aaagtgattt
     5761 ttcgcattca gcacttcatg aggaatacgt tcttgattca gcatatctga taataactca
     5821 gatgtttcaa ccgcaacagt tccgactaac acaggttgac ctttgcggta gcgatctttg
     5881 atatcttgca cgacagcgtg gaacttgctt tgtaatgttg ggtaaagtaa atctggacga
     5941 tcatcacgga taaccggacg atttgtcgga atctggtata cttggatgtt ataaatttct
     6001 ctgaattctt cttcttctgt tttagctgta ccagtcattc ccgcaagttt cttgtacata
     6061 cggaaatagt tctggaaagt gatcgtcgcc atggttttcg tttcgtcttc gatctctacg
     6121 ccttctttag cttcgattgc ttggtgaagt ccatctgaat aacggcgtcc atccatgatc
     6181 cgaccagtga actggtcaac aatcagtact tttccgtctt ggacaacata atcgatatct
     6241 aaaagcatga tatagttggc tctcaatgct tgatccaagt gatgggtcaa tgcagtattt
     6301 tcaatgtcgt ataagttatc caaaccgaat gtttcttctg ctttttcgat ccctgcttcg
     6361 gttaaactga ttgtttttga ttgtacatcg attttataat cttcttcttc tttcaaacgt
     6421 ttcacgaagt tgtctgctct tgtatataaa gctgtggatt tttctgcttg ccctgaaatg
     6481 atcagcggcg ttctcgcttc atcaatcaag attgagtcaa cttcatcgac aatggcataa
     6541 ttcagcggac gttgtaccat ttgatggcgg taaacgacca tattgtctct caagtagtca
     6601 aatcctaatt cattattcgt actataagtg atatcacaat tataagcctc gcgtttttca
     6661 tccgaagatt ttgagttgat attcaacccc actgttaatc ctaagaaatt ataaagttcg
     6721 cccatttccg tcgagtcacg ggttgctaaa tattcattga cggtaactac gtgtacccct
     6781 tcgccagtca gagcatttag atatactggc atcgttgcgg tcaaggtttt accttcacca
     6841 gtacgcattt cagggatatt tccatcgtga agcacgattc cacccatcaa ttgtacgtgg
     6901 tatggatata accccaatac acgttttgct gcttctcgga cgactgcaaa agcttccgga
     6961 agtaattgat ctaatgtttc tcctttttgg tatctgccct tgaattcagc agtttttgcc
     7021 tgtaattgtt catcagttaa tgctgccatt tggtcagcgt atgcttcaac tttttttgca
     7081 atgctatcta aacgttttag ttctttctta tcgttttcga taagtgaacg aatcaaattg
     7141 gccatgcgtt gtgtaatctc cttttccttc tgtgtattat ccagactatg tagactttac
     7201 ttttcatttt atcattagtt atagataatt gaaatatctt aagcgtatta aagtaagaac
     7261 ttcataattt attcatattt catctaaaag aggaggaaac tcaaaaaaac ttgcggcagc
     7321 tgtcagtagc tgctgcaagt tttcgttgtt atttaagtaa ggctgatcag tctgtttcaa
     7381 tcagtccgta ttttccatct ttacggcggt aaacgatact tgtaccattt gtttctgcat
     7441 cttcaaaaat aaagaagtta tgtcccagca tgttcatttg taagactgct tcttcactat
     7501 ccattggttt caatgaaagg cgtttcgtac gtacgatatc taattcagaa tcattttcgt
     7561 tttcgtcctc ttcattgaat aaagcagcag catctgcagt attcatgccc gtttcacggg
     7621 atttacgatt aatttttgtt ttgaatttgc ggatttggcg ttccaattta tcaacaacca
     7681 aatcgatact tgcgtataaa tctggagaag tttcttcggc acgtaataca agataaggta
     7741 atgggatcgt tacttccact tttgctgttt tttctgtata aacttttaag ttcacatgcg
     7801 ccgttgcatc gggtgcgtca ctgaaatagc gttctagttt gcctactttt ttctcaacgt
     7861 agtcgcgaat cgcttcagtt acttcgatat tttcgccgcg tacattatat ctaaacataa
     7921 aaattacccc tttcgtctac cacaatcaag aaggagaagg accactcttt ccctcttctt
     7981 aattctatta tatcgaactc taggttattt gcaaattaaa tcgctatcaa atttccacat
     8041 ctaattcatc tcgccaaaga aatggttcgg atgattttcg gctgtgcgac ctgcaaacaa
     8101 tctgctgcgt ggaaaagagt ctgtcctgtt gtatagacat catcaataat caatattttt
     8161 ttattttgta tcttagaaaa ggtgactgca agttcaaaag gttgaggcat ctccaatctt
     8221 tcctttcgcg tgttttttgc ttgagccagc agatgcttct ctcttttgag tagcatctga
     8281 aaaggaattc ttgctgcttt caacatctcg cttacttgat tgaatcctct ttctgttcgc
     8341 cttttttcag ataaaggtat tggacaatag atgtatgtcg ggtattcttt ttttatctgc
     8401 gtccatttat atgcaaaggt gcctgctagt cggatatctc ccataaactt gtattgattg
     8461 agccaggcct tcatattttc atcgtacaca aaaaaggcac ggtgctgaaa atcataggtc
     8521 ggatatttct tcttccattc ttgacagtca ctgcagtaaa cgggaataga ctttactttc
     8581 tttttcgtac tctctagatt gaaatggatt ggtttttgac agccagaaca gcctcttgtt
     8641 tccaataaat gaaattgtgc gcgacaaact gaacaagtct gaggtaatct gtatttcgaa
     8701 acaccaataa tctcgctgaa tgttaaattt tggaagatat ctttactgca gcaactgcac
     8761 ctcacagcat cttcttccct tcttcattca tttctttgat ttcctgacaa gcttttcgaa
     8821 tagctgcagt tttttcttca tagaaaaagt atacttgact gttcgtataa ggccctttac
     8881 gatcggctct tcctgcgatt tgtaccaaag aagatttagt aaaaaccgga tgatccgctc
     8941 ctaaaacgat aacggatatt ctttcaaatg tgactccacg ttcaaggatc atcgtggtta
     9001 acagtatatc atattttgct tctcgcattt tctggacttt ttccgcccgc tgattgtctc
     9061 ttgaagaaac atctgtgatc tcatatctcg gaagagcctc ttgaagtgtg gctttcaaac
     9121 gatgcatcat cgtgatactt ggacaaaata aaaggatatg gttttcttta attaattgat
     9181 gaatgatccg caccaaagat tttatcttct tcttgttctt gcatttttgt cgccaattat
     9241 tcatgaaaac caagacgggt tcaggaagca aacgccgatg aaagcgtaaa gcaagtttgt
     9301 ggatgtcaaa cgtctgcttg atttccttta gtaacttttt atcaggtgtg gcacttaagt
     9361 agatgaatcg tccgtctggt ttaatcgctg tttgcacagc atgagctaat cctgcatccc
     9421 cgttataagg aaacgcatcg atctcatcga tcactattaa atcaaaggac cgataaaaac
     9481 ggtatagctg atgaatcgta cagataacaa aagaagtaaa ggtataagcc gttgctgtat
     9541 tcccatggag caacgtgatt ttttcttctg gaaaaacata acgatagcgt aaaaacaatt
     9601 cattacaaac atcgactcgc ggtgtacaaa tcgctactct tcctccagct tttaaagttt
     9661 ccactaaaat aggataaagc atctctgttt tccctgcacc tgttacagcc caaataagat
     9721 gatgtctttt ttctgaatgg caaagtattc tctttgagat ttccgtttgt ttttcagtaa
     9781 gctgtcctgt ccaaaaaaag acgacttctc gaggttttgc ttcaggctga tcaaacaaat
     9841 ataaatcttg ttgagtgtcg catcgcccta aatatagaca atgtgtacaa aaataaccgt
     9901 aatctgcaag ctgtccatca atgacggacg tcctcattcc acagcgatga caaagaatcc
     9961 agttgcccaa acgttccact gctgcgatct tctcataatt tggtaaattt acctcctcac
    10021 agtctattgc ttcaatatct ctcgtcagaa gccttctacc ccaaaaatga ttcatattct
    10081 tcgccctaaa aaaatatacg aaaaaacaag cgatctattt tttggatcgc ttgttcgata
    10141 gttatactgt tctatttatt cacctatgag cgtgattgct tgatctaaca ctttttcgcc
    10201 attcatcata ccataatcag ccatattgat gacatctaaa ggaatgcctt ttggttccag
    10261 acgtttctca aaatcagctt tcataaagcg aacttgtggg cctaataaca acacatccac
    10321 gtctttattt gcaaggttgt tatctgcgtc agaagcggac acagcgaaaa tatccgagtc
    10381 gattcctttt gcttcagcag ctttttgcat ttttgttact agtaaacttg tgctcatacc
    10441 agccgaacat acaagcatga ttgttttttt agccatactt ttctctcctt tttaaaacaa
    10501 actatgcaaa cgttttcttc gcgtctgtta ctctattata taaaaagaaa gaaatttgtc
    10561 aacgttttct aaacgcggtt tatttaatca aatagccaac tagatttcac taatttattg
    10621 aacacgacat attctttgtc caaattgatg acaactactt catagcctgc atttatccag
    10681 ccataggcac ctttttcagg gtgtttataa tcatttgccc accaatctgt actttccctt
    10741 gctgttttgg gaagtccgtt actgggaaac agcagttcgt caaattgggt aaaggtcaac
    10801 gttacttgag agccgccatt gttcttcaaa taatgcgtaa ttgcatcgta ctttttcatt
    10861 cgttcctgca tccccagatc cacctgcctt tgtctttatt atcgcatact acagcaattg
    10921 cgcaaccgtt acagtgttga aacaacctag aactttattt atactgaata aagaaaatga
    10981 aaaaaagagg tgacaagatg atcgagcgct atcgtacaat aaaagaaaat ggacaaagtg
    11041 agattgagat caaaaaatca cgctttatct gttctcttag acgaatagaa tcagaggacc
    11101 aagcaaaaag tttcattcaa gaaataaaaa aagaacattg gaaagcgaac cataactgca
    11161 gcgccttcat cattggagaa aaaaatgaaa tccagcgaag cagcgatgat ggagaaccaa
    11221 gtggaacggc gggcgtaccg atgttggaag tcctcaaaaa aaatcaactg atcaatgtag
    11281 ctgcagtagt cactcgatat tttggaggaa cgaaactcgg cacaggcgga ttaatacgag
    11341 catacactca tgcggtctct caagcattgt ctgacattgg aatcgtagaa ggtaccttgc
    11401 aacaggagat ctctgtgatg atcacgtatc cgcaactagg aaaattacag aattatcttg
    11461 aactccaaca tttttttata aaagaaatcc aatatactga tcaagttagc gtcatctgtg
    11521 ctgtagatga aaaaagtgct gaccacttta aagaatccat cattgagctg ctgaacggac
    11581 aagtccaatt tgaagagggt tctgtttctt atcacgagca actgataact gatcatatat
    11641 aaaaacaggt gattctgatt ctcttttatt tctaataagg aatcagggat cacctgtttt
    11701 ttatttttcc aaataaaact caaaacgatt tcctacgtat tgcgtacgca catactcaaa
    11761 cggcgtaccg tcttcaaaat aagaaatctg gcgcaaacga agaactgcat ctcctcgttt
    11821 tacctctaaa tagtcagcaa ttttctcaga agccaacaca gcagtaatcg tttgattcgc
    11881 tggaccgatc tttttcccgc ctttttcttc tagcgtgcga tacaacgatt cagtaatctc
    11941 tgctttgctg tagccatcga tcagcttttg tggaacactg gcaacttcaa aacaaatagg
    12001 gacatcatct gcgaaacgaa tacgttccat tcgcaagatc gtgtcatctt tactcaagtt
    12061 tagtttttcc atttcacttg agcttggcga agtcaagaaa taagagattg tccgactaga
    12121 cggtactcga ttttgtgatt ccataatttc tgtaaaactt gttgcaccag acattttttc
    12181 ttgtactttt tctcgcgcaa catacgtacc cgaaccgatc tttctttcta agattccttc
    12241 atctgccaag ttttgaattg cttgtctcaa cgtcatacgg ctgacattga atttcactgc
    12301 taattctctt tctgaaggaa gacggtctcc gactttccat ataccctgtt cgatttcatt
    12361 ttttaattgg tcatgaatct gtatatatac aggtaattga ttcgacataa cgtacacccg
    12421 tcctttcgtt tcttctatta taactggtat atacctgatt cacaactgaa aaagataaag
    12481 gtttctatcc atcaacagag gatttagaca cacatcgttc tccctactcc tattgtcaga
    12541 aacaattttt tagatatgtt caacctagaa aataacaaaa gaccctaaaa tcgatgaaaa
    12601 tgccgactta tggatctttt gttattatta gcggttttta gccatccatt tttttgtatg
    12661 attcgttggg cgttttgatt ttacctggac cgcttttccg ccttttttcg gaatattcac
    12721 ttcaatattg tatttttctg atttgaccaa atcatataac ttttcagctg cttcgtctac
    12781 tttttctttc catttcatgt ggatccctcc aattcttgta gttaacttaa ctctatctta
    12841 attcagcaga atcttcaagg aacaaggtag caaagcaaaa aaaagagctc tcgaactaac
//
LOCUS       DAIGWC010000074        12861 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.075, whole genome shotgun sequence.
ACCESSION   DAIGWC010000074 DAIGWC010000000
VERSION     DAIGWC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.075"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..135
                     /locus_tag="NOB74_002265"
     CDS             <1..135
                     /locus_tag="NOB74_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1221428.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
     gene            complement(313..2310)
                     /gene="tkt"
                     /locus_tag="NOB74_002266"
     CDS             complement(313..2310)
                     /gene="tkt"
                     /locus_tag="NOB74_002266"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCI1221429.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2412..2663)
                     /locus_tag="NOB74_002267"
     CDS             complement(2412..2663)
                     /locus_tag="NOB74_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HCI1221430.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2810..3433
                     /gene="lexA"
                     /locus_tag="NOB74_002268"
     CDS             2810..3433
                     /gene="lexA"
                     /locus_tag="NOB74_002268"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HCI1221431.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3613..3831
                     /locus_tag="NOB74_002269"
     CDS             3613..3831
                     /locus_tag="NOB74_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221432.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4120..4632)
                     /locus_tag="NOB74_002270"
     CDS             complement(4120..4632)
                     /locus_tag="NOB74_002270"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HCI1221433.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="NOB74_002271"
     CDS             complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="NOB74_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HCI1221434.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7085..7528)
                     /locus_tag="NOB74_002272"
     CDS             complement(7085..7528)
                     /locus_tag="NOB74_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HCI1221435.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7529..8317)
                     /locus_tag="NOB74_002273"
     CDS             complement(7529..8317)
                     /locus_tag="NOB74_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1221436.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8314..9255)
                     /locus_tag="NOB74_002274"
     CDS             complement(8314..9255)
                     /locus_tag="NOB74_002274"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HCI1221437.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9432..10019)
                     /locus_tag="NOB74_002275"
     CDS             complement(9432..10019)
                     /locus_tag="NOB74_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HCI1221438.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10240..11547)
                     /gene="obgE"
                     /locus_tag="NOB74_002276"
     CDS             complement(10240..11547)
                     /gene="obgE"
                     /locus_tag="NOB74_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HCI1221439.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11841..12851
                     /gene="gap"
                     /locus_tag="NOB74_002277"
     CDS             11841..12851
                     /gene="gap"
                     /locus_tag="NOB74_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCI1221440.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
BASE COUNT         3568 a         2877 c         2279 g         4137 t
ORIGIN      
        1 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
       61 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      121 ttttgtctcg cttaatttga caaataatat tctcaagaaa cacaaactaa tccgaagaat
      181 tctttgtttt gtcatttaaa tgtaacatag ccgaaaacga aaagtaatat tgatttattc
      241 ttctaacaca taaagaacag ctgtctccaa cttgcagaca gctgttctta tcagtcaaac
      301 aattgcttgg atctatgata gttgattgta cgtattcacg acattttcta ctgtaaatcc
      361 aaattcttct aaaattttag tgccaggggc agatgcaccg aaatgatcga ttgtaatcgt
      421 tgcgccctct gttcctacgt agcgttccca tccaaatgat gcagcagctt cgatagccac
      481 acgtttcttc actgatttag gaagtacact ttctttatat tcagaagatt gtttttcaaa
      541 gaggtcaaag cttggcatag aaacaacaga aacatctttg cctttttcag ccaattcttt
      601 ttgagctttc acagccaaat caacttcaga acctgttgca atcaaaatac cttctggtgt
      661 ttctccttgt gatggagaaa gaacatacgc gccttttttc accatttcat ctgctacttc
      721 ttttgtagaa ggcaatactg gaaggttttg acgactcaat acaaggatag taggcgcatc
      781 tgttgtctcc atcgctactt tccaagcagc acgtgtttca tttccgtctg ccggacgaat
      841 cacttgaaca ccaggcatgc agcgaacaga tgctagttgt tcaatcggtt cgtgcgttgg
      901 tccgtcttct ccgacagcaa ccgagtcatg tgttaagacg taaacaacag gagtatgttg
      961 gattgctgct aaacgaactg ctggtcttag ataatcgaca aagacaaaga atgttccacc
     1021 gtagatacga gttccgccat gaagttggat accattcata gccgaagcca ttgcaaattc
     1081 gcggacaccg aaccagatgt tgcgtccttc ataatgttca ggagtgaaat ctttatctgc
     1141 agccaccatt gtattattgg aacctgacaa gtccgctgaa ccaccccaga agcttggtat
     1201 agctttcgat aattcttgga tgacttcttt acttgaaaca cggcttgctt gactgcttcc
     1261 aacttcataa gttggcaatt ctgcatccca gttttctggt agtttgccat caaaagcatc
     1321 ttcaaattgt tgtgctaatt caggataagc ttttttataa ttggcaaaca tttcattcca
     1381 tgcatcttca gctttttgtc cttcttctat catcgtttga tggaagcggg cagctacttc
     1441 ttctggaaca gtgaaatctg gatactccca accataaact tctttagcca tcttgatgcc
     1501 atcttcacca agaggagcac catgaacagc agatgttcct tctttaggag caccatagcc
     1561 gatgactgtt tttacttcga tcaatgttgg tttgtctgtt tcagcttttg cttcttcaat
     1621 cgctttagag attgcttcta ggtcatttcc gtctttcact aagatatgtt gccagccata
     1681 tgcttcatag cgagcaccaa cgttttctgt gaaagctttt gaagttggac cgtctagtga
     1741 aatatcgttt gaatcgtata aaacgatcaa tttccctagt ttcatatgac ctgccatcga
     1801 acttgcttct tgagataccc cttccatcaa gtctccgtca ccgcatattg catacgtata
     1861 gtgatccatc acattaaagt tttctttgtt atacgttgct gcaaggtgcg cttctgccat
     1921 tgccataccg acagccattg caatcccttg tcctaatggc cctgtagtgg cttctacacc
     1981 atctgtatga tgtacttcag gatgtcctgg tgttttagaa tcccattgac ggaattgttt
     2041 caaatcatcg attgtcactt gatagccagc taaatgaagc aagctataca acattgctga
     2101 cccatgtcct gccgaaagaa cgaaacggtc gcggtcagcc cagttttttg atgtcgttgg
     2161 atttactttc aggtgttttg tccataacgc atatgccata ggtgctgcgc ccatcggcaa
     2221 tccaggatgt cctgagtttg ctttttggac tgcttcaata cttaatgtac gaattgtgtt
     2281 aacgccaagt tggtcaattt tgtcaaacaa aataacccct cctattaatt taggtttttt
     2341 ttacctttat ttcttacact ttcattctat aagatgtcac acgaaaaagc aatctttttc
     2401 agtatttttt actaaaagtt gtcatttcgg ttgtgtaagc cttttttctt ttggatttct
     2461 tttaattttt ccggggtcac gtcattgccc tcaggatcga cgactttcat tccttcgata
     2521 tgatgacgca taccggaacg aaaagcttcc aaatactctt tgcgcaagtt gatttgttct
     2581 tgttcttcgg cttttgagag accattttcc ttctttttac gtgcaagttc attgatccgc
     2641 tctatttttt caggtgacag catgctcagc cctcctttta ctctccttca tattatataa
     2701 aaactgaaaa aaaaacaact agataaacta aataaaatac gaacattcgt ttgatttagc
     2761 gctttttata tggtactatt tatttatcaa gtgaaagaag gtgtaccttg tggcccgaca
     2821 aactgaatca agacaaatcg aagtcttacg atatatccat gaacaagtaa cccaaaaagg
     2881 atacccgccg actgtccgtg aaatcgggga agctgttcag ctttcttcta cttctactgt
     2941 tcacggtcat cttgcacggc ttgaaaaaaa agggtttatc caaagagatc cgacgaaacc
     3001 tcgtgcaatc gagttgacaa aacaaggttt agaaaagatt gggattcgtc caacaactat
     3061 tccagtactt ggcgtcgtaa cagctggaga acccatttta gcagtagagg atgcttcaga
     3121 cttctttcca atccctccta atctttcttc cgaagaaggc agtctcttta tgctgacaat
     3181 tcgtggagat agtatgatca atgctgggat attggatggt gacaacgtga tcgttcggaa
     3241 gcaagaaact gctcaaaatg gcgatattgt cattgcaatg actgccgagg acgaagcgac
     3301 ttgcaaacga ttctataaag aaaaaaactt tttccgtctg cagcctgaaa acgacttgct
     3361 cgaaccaatc atcttagatc aagtatctat attaggacga gtagtaggac tttatcgtag
     3421 tcatatctat taattgctac taattaaaag aaaacttttt aaaaagagtt tgagacgttg
     3481 gtctcaaact cttttttcgc ccgggttctt cttctttcaa atttttatca cttccctctt
     3541 tacaaaccga acaaatattc gtatactaaa tatacgaaca attgttcgca taaattaaag
     3601 aggtgagaat tcatgaaatc aatgagacgt cttggcttag tattaactgt tttgttttta
     3661 ggtattatta ttggtaattt cggcatacgt ccagctttac ttgtgtttgt tccgttattt
     3721 actttgtggt tcatgttgtg ggatgaaaag aagtaccgtc aatctgagcg gcgcagaatt
     3781 catgaagatc atttctatca tgagccctac tacagatcca ggcaatcata ataaggattg
     3841 actgctaatt attcaaaaga caagaagtta aacttttacg ggggtgtgac aaaaatcggt
     3901 cacatccttt ttttcgaata aacggtgttc taaagccagt ttttcggtat taagtcaaat
     3961 tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat ttataaaaaa
     4021 atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt taaaatcgct
     4081 tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca ttaatgtaat
     4141 gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga tcaaaaatgc
     4201 gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt tgattgttcc
     4261 tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa tggcatcctt
     4321 atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga tggtttctcg
     4381 aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat aagcaacagg
     4441 acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc gtttttcttt
     4501 tgcataattt acgatttgtt tagtagcttc ccgataagcg tcaccatctg ccatcagtgg
     4561 ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg caatataatc
     4621 ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg gtaggaatat
     4681 cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgtcgctgg tataatctgc
     4741 tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg ttctctattg
     4801 taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt tcagggatac
     4861 gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct tgagaatgga
     4921 tcaatttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa taggcctcat
     4981 caggtgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa acttctttca
     5041 gatccgctaa atcatctgga caatccataa caactagaga gtttggtttt cttttttcaa
     5101 ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg ataatctcag
     5161 gcacgaattt caacgtcgaa gaatcaaatg ctaaataaag gctaccttcc gacgttcggc
     5221 tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc acagaaaaat
     5281 cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa agctttccta
     5341 ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca aaagcgaccg
     5401 catcaagctg actcgatgca tcggaaagga caaatttcag atgctgttgg tttgctccga
     5461 ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa ggattatccg
     5521 taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact tcatttggca
     5581 gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga tgatcgacta
     5641 tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc gttaaaccga
     5701 ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca agcatttcaa
     5761 aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct tcttttaaag
     5821 taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca atgcccaaaa
     5881 cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta ttgaccatcg
     5941 ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg atctcattca
     6001 atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac gagacggcag
     6061 gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa aaaccgatcg
     6121 ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc tgaagtccta
     6181 tccgttctga atgatgaatg gcatcgattc ctaatgaaac aaggattcga ttctcatcag
     6241 tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat tctgcaggcg
     6301 gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc aaatctggaa
     6361 atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct ggtaaattct
     6421 caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga gcgtatgcta
     6481 ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt ccttcttcga
     6541 tcttttcttg gtataccgat tggtttggtc catacccatg ctcaaatcga tttggcagga
     6601 atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt gcactggtga
     6661 tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt acagcttctt
     6721 ggattcggct gattgcttta tccatatcgt gtatcagata cggatcatgt aattcttgtt
     6781 cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt tgccacagta
     6841 acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag gattcagaag
     6901 gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca ctcctaactt
     6961 agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa aaacagatca
     7021 gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt atgaaatatc
     7081 cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt tcttccggcg
     7141 ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa gcagcttcca
     7201 actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct tcaattttct
     7261 tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt tgcttttttt
     7321 gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc agcgcagaac
     7381 cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt acaggaacat
     7441 ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat ccaagaatca
     7501 cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg ctggctaaat
     7561 aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa ataaacggtt
     7621 gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc aacttggcag
     7681 gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca gccttatcga
     7741 agaaatttgt ctcgattgga cctggattca ctgtcgtaac agctacgcca agtggtttca
     7801 attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca gaataaaccg
     7861 ttgattttgc agttgccatt tttccagcca tagaggcgat attaatgata tgaccttgtc
     7921 ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct aagatgttga
     7981 cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg aaaatcccaa
     8041 aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc ttttcatata
     8101 attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc tctttgccgc
     8161 tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt gcgcaactta
     8221 taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga ccgcctgaac
     8281 tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct cgcgaaatgg
     8341 aatctcaatg ctatcaaaat ctttcataat cgtcgtgttt tcaaacactt cttgtgcttc
     8401 tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag taagtagcag
     8461 ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg aatggaaata
     8521 gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca gaatatcgct
     8581 attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa tagtcacgat
     8641 tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc catcttctag
     8701 ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa tacctaattc
     8761 ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac gataaccaaa
     8821 actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat cagtaaaaat
     8881 cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg tttgcgaaat
     8941 acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct ctaatggcgt
     9001 atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa tatgatcgcc
     9061 gtgtaaatgt gtaatgaaaa ttttaccgat ttttctcgga cgaatagtcg ttcgcaaaat
     9121 ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct cgtctaaaag
     9181 tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac ctgttcctaa
     9241 aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt ttagggtaaa
     9301 aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa cgttctaaag
     9361 cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt gagatcctct
     9421 gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt ttgcggatgt
     9481 ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc tttcgcatca
     9541 tgcacatctt tttcgacatc ttcataatcc aagcgagtaa tttctccgcc taattccatc
     9601 attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat cagtcctgta
     9661 gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc ttttatttct
     9721 ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa aatccctagc
     9781 ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga tttgttatta
     9841 ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg atcatggctg
     9901 acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt gatttctgaa
     9961 aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg tttgctcatt
    10021 aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgaa aaataagaaa
    10081 agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta tcacagctcc
    10141 tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct cccttaaatc
    10201 tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa attcaaattc
    10261 aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa gagcttcatc
    10321 cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat gatcgaaatt
    10381 cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg catctgaatc
    10441 acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag tttcttcttc
    10501 cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg ctgtagcatt
    10561 caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg ggatgtcatc
    10621 agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta gattttccgg
    10681 tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta gcaagcgtaa
    10741 gttataagta gataattctt tgttgatggc aagatagtct tcataaggat ctcgtccttc
    10801 catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat gacgaaggaa
    10861 ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca agtctgctgc
    10921 ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttaggtacga gcgtcgtgaa
    10981 atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag tcgatttccc
    11041 gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta gttcgatttt
    11101 tcgctcttgt cctggttcac cgttttcagc aatttccggt gcaggattcc gaggagaggc
    11161 aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg tttgaccatt
    11221 ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg ttccttgtgg
    11281 tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca tcccattttc
    11341 acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac gtaacccttc
    11401 atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg gtccgccgtc
    11461 aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc cagctttcac
    11521 atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt attcatttat
    11581 ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta tcggtgaaat
    11641 ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt ttatcatttg
    11701 gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa tattctttgc
    11761 gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac agcaccccta
    11821 ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt gggcgtattg
    11881 gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta gtagcaatca
    11941 acgacttaac aagtccaact atgttagcac aattattgca atttgactct actcatggta
    12001 cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc gaagcaactc
    12061 gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac ggtgtagata
    12121 tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg catttagatg
    12181 ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc atcgtctata
    12241 acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt tcatgtacaa
    12301 caaactgttt agcacctatg gcttatttct taaataatga atttgggatc gaagttggta
    12361 caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga cctgtaaaag
    12421 gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat tctactggtg
    12481 ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa ggacacgcac
    12541 aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg aaaacaaaag
    12601 taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat ccttcattcg
    12661 ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa ggttcgatct
    12721 ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt aaaactgttg
    12781 catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta gaaaaattcg
    12841 ctaacttgta atttgataga t
//
LOCUS       DAIGWC010000075        12738 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.076, whole genome shotgun sequence.
ACCESSION   DAIGWC010000075 DAIGWC010000000
VERSION     DAIGWC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.076"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="NOB74_002278"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="NOB74_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCI1221441.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="NOB74_002279"
     CDS             complement(323..892)
                     /locus_tag="NOB74_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HCI1221442.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="NOB74_002280"
     CDS             1078..1980
                     /locus_tag="NOB74_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1221443.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="NOB74_002281"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="NOB74_002281"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HCI1221444.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="NOB74_002282"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="NOB74_002282"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HCI1221445.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="NOB74_002283"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="NOB74_002283"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HCI1221446.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="NOB74_002284"
     CDS             8548..8733
                     /locus_tag="NOB74_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HCI1221447.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="NOB74_002285"
     CDS             complement(8795..9991)
                     /locus_tag="NOB74_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI1221448.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="NOB74_002286"
     CDS             complement(10161..11597)
                     /locus_tag="NOB74_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCI1221449.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="NOB74_002287"
     CDS             11890..12699
                     /locus_tag="NOB74_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1221450.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3803 a         2673 c         2250 g         4012 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgacaatt
//
LOCUS       DAIGWC010000076        12735 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.077, whole genome shotgun sequence.
ACCESSION   DAIGWC010000076 DAIGWC010000000
VERSION     DAIGWC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.077"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            94..537
                     /locus_tag="NOB74_002288"
     CDS             94..537
                     /locus_tag="NOB74_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1221451.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(543..1727)
                     /locus_tag="NOB74_002289"
     CDS             complement(543..1727)
                     /locus_tag="NOB74_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HCI1221452.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1995..2693
                     /locus_tag="NOB74_002290"
     CDS             1995..2693
                     /locus_tag="NOB74_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCI1221453.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2700..3377
                     /gene="nth"
                     /locus_tag="NOB74_002291"
     CDS             2700..3377
                     /gene="nth"
                     /locus_tag="NOB74_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HCI1221454.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3503..4036)
                     /locus_tag="NOB74_002292"
     CDS             complement(3503..4036)
                     /locus_tag="NOB74_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221455.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4333..6714)
                     /locus_tag="NOB74_002293"
     CDS             complement(4333..6714)
                     /locus_tag="NOB74_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCI1221456.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6704..7351)
                     /gene="recU"
                     /locus_tag="NOB74_002294"
     CDS             complement(6704..7351)
                     /gene="recU"
                     /locus_tag="NOB74_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HCI1221457.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7415..7954
                     /locus_tag="NOB74_002295"
     CDS             7415..7954
                     /locus_tag="NOB74_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HCI1221458.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8044..8463
                     /gene="gpsB"
                     /locus_tag="NOB74_002296"
     CDS             8044..8463
                     /gene="gpsB"
                     /locus_tag="NOB74_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HCI1221459.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8485..8852
                     /gene="rnpB"
                     /locus_tag="NOB74_002297"
     ncRNA           8485..8852
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="NOB74_002297"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9061..10227
                     /locus_tag="NOB74_002298"
     CDS             9061..10227
                     /locus_tag="NOB74_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HCI1221460.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10273..11769
                     /locus_tag="NOB74_002299"
     CDS             10273..11769
                     /locus_tag="NOB74_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HCI1221461.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11850..12533
                     /locus_tag="NOB74_002300"
     CDS             11850..12533
                     /locus_tag="NOB74_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI1221462.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2229 c         2630 g         3603 t
ORIGIN      
        1 tggtttcaga ttgggttttc ctacaaaata tttttatctt tgttgaatag gaaacaaaaa
       61 aacaatataa tgaaagaaaa agaaggtgta gaaatggata aaagacaact gctaatagaa
      121 gaatatctgg atttagctaa tgagattatt catcgtaata aaccagaaat ggaaaaagaa
      181 tttgcaggat ttactctaaa tgaactagaa gtgattgaac atatcgggaa aatccctgat
      241 cctaacgtga caaaattagc gaatgctagt tacatgacta gaggagccat cagtaagcta
      301 acaaaaaaac tgatagctag agggatcata aacacttatc aaagcgaaga gaataaaaaa
      361 gaaatctatt ttcaattgac gccaatcgga caaaaaataa ggaatagaca cgagcaactc
      421 catcaaaaat gggtacagcg agatgctact gtatttgaaa atatgtcaaa agaagaattt
      481 gacacagtat ttcgttttat cggtcgatac agagaattta tacgaagtag caaatgaagc
      541 tactattttt tattgtagtg ataataggca aaaatcataa gcaaaaatcc gaataccgtc
      601 ggaagaaatg gtgctgcagc ataaagctgt cctgcgatta gcgggccgat gacgcgcgat
      661 agagattgta tactttgggt accgcccatt acaagacctt gctggttatc tgagacagaa
      721 ttggatagtt ggccattgaa tacaggagta aaaatagaat caccgaaacc ataacagata
      781 atcccaaata aaaacaaaat cggcagtaga agaattccag ataatgtgat gaatagatag
      841 gcgaggattt cactgaacat ccctattctt gtgatctgct gttctgaaaa ttttttgagc
      901 aatcgaggca taatgaacaa ttgcgagaca gtatccaaga ttccaatcaa agagaagctt
      961 aaaccaacca acccagcctt ccactgaaag gcgtcaatcg aaaattgaga aaagatagat
     1021 tgaagagagc cagctgccaa ccaaacagca aaacctgctg tcaataaagg aataacggat
     1081 gaaatcttga ataattgttg taattggtga aaaggtctta catgggagaa acttaaatct
     1141 actgaacgtt tttttattgg aaggctttct agcataaatg tgtagccata aacggcattt
     1201 aagaaagtaa agagtgctcc aataaatata ggaacagaat tccccaactc agctaataga
     1261 ccccctataa taggacccag cgttgttcct ataccgacta aagcacccat ccatccaaaa
     1321 actttggttc tttcattagg ttccgtgatg tcggcaaagt aagcatataa ggtggagatt
     1381 tctcctgccg tcaatccttc aatgatacga ccaaggaaca acatccatat cgaatttcct
     1441 aaaccaaaaa gcaaatatcc gatacttgat cctaataaac tgataataag gatcggatga
     1501 cgcccaaaat gatcacttaa gctaccgaga atgggggcag ataagaaggc agctagagca
     1561 taaacagaca tgagcaaagt gatatagaaa gcttgctgat gtatggagtg agaataaggc
     1621 agcgttaaaa acggaagtac aggactgacg atagtaaatc ctaatccagt gaataagaca
     1681 gagacgtatc caaaaacttt agaatgttta tttgtgaaac tgtacatgta aaaactcctt
     1741 tatgcaataa tgttaacttg gaaacaaaaa tagtgtatag taattttgtt tccttgtcaa
     1801 cattctaagg aacagcgaaa tctacttaat ttatttattc cgaaaagtga agatacgcat
     1861 caaaaacatg aacaaacaaa aatcaagtag acgacattgt aaatctgacc gatcagtgaa
     1921 gtaaatagaa aagaaacctg ttcttgcttc ccatgttttt tttacgtata ctgtgattga
     1981 gcggaggaga aatcatgttg aatttagaaa attacttaag cgctggacaa acagtcatat
     2041 ctaatctttt acttaaaaat tatcatagga tcggtctaca atctgaagaa tttttatttg
     2101 ttctacagtt gcatatggca cagcttgaag gagatacttt ccctgatttg cagatgattg
     2161 ctatggatat gggaatcaaa caagatcaga tttttcaaat actggatcgt ctcgtaacaa
     2221 atggatttat caagatagaa acgacgattg tcaacggtaa aaaagcagat cgatataatc
     2281 tttaccccat ctatgatcta ttaggtgagt atttaaaaac acaagaaaaa aaatacgaag
     2341 aaaaaacaca agaaaaagaa atccagtcag tgtatcaatt atttgaacaa gaatttggac
     2401 gcccgctttc ttcgatcgag ttccagcgga tcggacaatg gctagaagaa gaccattatc
     2461 agccggaaat tttgaagcta gcactgcggg aagccgtatt aaatcaggct tatagtttta
     2521 attacgttga ccgcattttg ctatcgtggg aaagaaaaaa tctacgtaca aaacaacaag
     2581 tggaagaaga ccaaaaacga agaaaacagc agcttcttca aagagaagta gaacagtcag
     2641 ctcaacaaga agaattgccg aaagtctcac tgaaaaattg gttggaggag tagcggaata
     2701 tgttaagcaa acaaaaaaca atggaagctc tagaaacgat gtatggaatg tttcccgaag
     2761 cacatggaga actcaagcac aataatccat ttgagttatt gattgcagtg atcttaagtg
     2821 cccaggcgac agatgtatca gtgaataaag caacgccaga tttgtttgcc tcttttccga
     2881 cacccgatgc gttagcagaa gcttcaatcg atgaaatcat tcttaaaata aaaacgattg
     2941 gtttgtatcg aaataaagca aaaaacatca aagcgtgtgc acagcagctg attgaacgtt
     3001 tcgatgggca agtgccaacg tcaagagaag aattgatgtc tcttcctggt gtaggcagaa
     3061 agacagcaaa tgtcgtattg ggggatgcat tcgggatacc agcaatcgca gtagataccc
     3121 acgtggaacg tgtctcaaaa cgcctgagga tctgcaaact agatgctacg gtcatggaag
     3181 tagaagaaac actgatgcgg aaagtaccac aagaattatg ggtaaagaca catcatacac
     3241 tgattttttt tggtagatat cattgcacgg caagaaatcc caagtgcgag gtatgtcctt
     3301 tgctatcaat atgtcaagat gggaaaaatc ggatgcgtct aaaagaaaag gcgctaaaaa
     3361 agaaaccacg cctgtagacg tggtttcttt aattgcaaat aaatgtatga attatcttgt
     3421 tattatggag aaaagctgtt tcgtttatct tttttgcatg aaaaagtaaa tgtacatact
     3481 cagtagctag gatggtaact tattacaatt tattgcgata aaaataaaag ttgttatttt
     3541 tattgggaaa atacccgatg tagaaaataa tgccttccaa tatacctata aaataagtcc
     3601 agtattccaa aggattatat aaataagtga cgtatctatc taaaggtgta ataaaaatga
     3661 taagtgataa taaaaaaata ccatttataa ctaaacataa actaatggat ttgggcggtt
     3721 tcaggctcat cagaaaaata tagattctgg tgaacaacaa ccataaaaaa gtgagaatca
     3781 ttgcatgaga gcttctttcc ataaattttc ctttaagagt agtgcttaaa agtacagaaa
     3841 aaataataaa tgcaaggata ggagcaatta aagtaaattt atttaataat aaacaaaatt
     3901 tttcagcttt tttattcttg gaataacgag gtattgtttt cgataaaaaa agatggtgca
     3961 gacaaattat gataattaag catactatca gataactcaa aatgaagcct tctttcaaaa
     4021 aattattcaa aaccatatat tgtatttttt atttgataat aacaatggga ttattaagaa
     4081 gtggcactaa ataaaagact agtgtgtatt tagccgattt aattataaac aagtaaatgg
     4141 ataaagtata tgtaatgata aaagaaaaat ggattttcta atttttaagc taaatgttag
     4201 atcacacatg tatatgctgg atagtcttat aaaaaatcat gtaatacagc ttggtacatg
     4261 atttttattt gtagctgttt tttacataga cacaaaaaag aaaccacgct tgtagacgtg
     4321 gtttcttttt tactatctgt ttccagaagc tgaggtgctg ctggatggtg tatggtcatt
     4381 tgcagcatcc gctccgctag ttgctggctc actggaagaa gcaggaggag cagatgaaga
     4441 cggtgtcgag ctttcttcgg atgaagaaga aggaaccgtt gttgaagacg ctggctcgct
     4501 tgtttctgct gtcgtgcttt cttttgagga ctcagcagtt gattcgcttt gactagtaga
     4561 gctagagctt tgagtcgttg tctctgttgt tgagcttcca ggagtctgga catagctgga
     4621 agatggaata gttgttgatg gtgtaattgc attcgatcta gctgtatatt gatctttgta
     4681 gtacagttca ccgcccacac gaattaatcc gcttggcatc tcccagtctg tatttgtcac
     4741 gttagctgaa acatactgca taagctcgcg ataaacatca gaggctacgt gtgacgattc
     4801 tgaagtgaca ggcgtcattt ttttattgta acctgtccac acggaaatcg aataatttgg
     4861 cgtatagccc gcaaatagga tatctggata caccccagaa gaaataccaa gttttgcata
     4921 ctcgtcatct gtgtaattgg atgttccggt cttaccggct tgatataacc cagcgatttg
     4981 cgcattcgta ccagttcctt cagtgatcgt atcttttaaa atgtctgtga tcatataagc
     5041 tgtttctgga gacatggctg tttttccatc tggctcataa gtttcttctg ttccgtcttg
     5101 gaagacgatt ttattaacat attgaggttt gtaataagtc cctccattgg cgaaagccgc
     5161 ataggctgct gccattttta aggaagaagc tccgtatttt gtcccatctt gttcttccgt
     5221 attactagag atcgcattcg attgatggat cgtactgtat tcgatcccaa gattttttaa
     5281 gaaagaagcc actttatctg aaccgacttc attgaataat ttgactgctg gaacattacg
     5341 ggataagtaa agtgcttggc gtaaagtaat ggtgcccata tattgattat cccagtttcc
     5401 tacaggagtc gaagtccctt catagttata cggtgcgtca gtaatagttt ttccagtaga
     5461 atatttcaaa tattcaaaag ctggtccgta atctgtgaca ggtttcatcg tagaaccaaa
     5521 atcacgggaa gtattcactg ctaagttgtt gcctaaagtt acgtcttctg cgatgtgacg
     5581 tccgccaatc tgggctttta ctttcccggt attggtgtcg ataagggtgg aggcaacttg
     5641 catctcgtcg tctgggtaag agacatactg atccgtgttg acgatatcat atagtttctt
     5701 ttgggcgtcc agatccaaat tcgtataaat ctctaaaccg tctgtgtaga cattcttatc
     5761 tgttttttct tgtacttcat tgatgacttc tttgacataa ttatcgacga tcttagtatt
     5821 gtcatcggat tgagttagtt cttgcagacc atccgttacc ggtacattaa cagcttgatc
     5881 atattctgtt tgagagattt tttcgttttg aagcatcgta tacaaaacag tatctcgtct
     5941 tttcttcgcc tgatctggat aaacataagg atcataggcg gaaggggctt gaggcatccc
     6001 agcaagcaat gctgtttgcg gtaaagaaag ttctgataat ttcttaccaa agtacatctc
     6061 agaagctgtc tccatcccgt acaagccgtt tgacatatac actttattta cgtagtaggt
     6121 caagatctct tgtttcgatt ttttttgttc caatcttaca gccatccacg cttcttgggc
     6181 cttgcgtttc agagtctgat cctcggcact ggtggagaag aaggaaagtt tgatcaattg
     6241 ctgtgtcaaa gtacttccgc cttgcagtcc gccagaggta aagttagaga gggcagaacc
     6301 gatgatccga atagggtcaa ccccgatgtg tttataaaaa cggcgatctt ctaccgacac
     6361 gatcgcatct tctaatgttt tcggtaattc attcgcagaa attttttcac gcttttctgc
     6421 gcctaaatct tcgaatagtt cgccatcttg tgtatatagt ttggaagata cggtagcgtc
     6481 taatttttta tccgtcaatt cgggcgcatc ttttgcgtaa taccagaaaa gtcctacacc
     6541 tgctaaaaag aggatacaga aaaatgagag tattcctaaa aggatcttga taaataatcc
     6601 ttttttatgt gttccagagg actttccaga acctttgcca gaattcttct tcacactctt
     6661 tttaggagta ggctgtttct gtcgtctaga gcttctagtt tgttcatttg ccattcttgc
     6721 tttctccttc aatagataat gttgataaat agaagtcaac cgcgtccaaa taaggaatcc
     6781 gcggagaaat accagttttg atctctattc ctagttcttc gatcaaagat aaaggtagtg
     6841 atttgcgtcc tttttccttt tgggcgtccc agtaagcaat caaatgaaca ctattcaaat
     6901 aaaaacagcg cttcaaagac gaaaaccata acaagacaaa gcagacccca ttttgttcga
     6961 ggcatgcttt catatgttcg atttgatggg catggaagtt tttaaaggga aaagatgttt
     7021 tgttcttggt ttcttttgct tcaaagtcca agtaaaagcc tcgatagacg ccattatagt
     7081 ctgtagttga ggcttgggta aagtaggctt ccttgatcac agcagcactt ctcttaggat
     7141 agtctacttt cacgatttgg ataggggtag gctttttatg gataaccgcc aacccgcggg
     7201 aaagataata tttattactt tcattgattg cttcttcaaa gcgcatcccc cgattgccga
     7261 attcagtgat ctgatttctt ttttcttgaa ttttttcgac gggagaggca ttcttataat
     7321 aaggttggcc atttggatag cgcaatacca tctttaatca cactcctagg ccacattata
     7381 gcaaaaaagc ggatagaaag aaaaggaatc tgagatggat aagtcaaaag taatctatgt
     7441 gtctgggtat cgaagtttcg aactcggtgt ttttaaagaa aatgatccta aaatccaagt
     7501 tgttaaaaat gttttaaaaa aagaactcca tcagttagca gaagaagggc tggaatgggt
     7561 acttgtcagt gggaatttgg gcgtcgaact atgggctgtg caaatagtag cggaattgaa
     7621 agaagaatat ccggaactat ctcttggtat tttgtatcct ttttctgatt ttggtaataa
     7681 ctggaatgaa gggaaccaag aaaaaaaaca attagcagaa caattagcag attatgtcga
     7741 agctgttagc catcaaccct accaatcacc tagtcagcta aagaatcaca ctcgttttat
     7801 acttgagcat acagtgggct gtctgctgat ctatgatgaa gaattccctg gaaaaacgaa
     7861 gtattttttt gaagatgcac agaattacca agcagatcat ccctacgaaa ttcggctgat
     7921 cagtatggac gatcttcaaa attttagtga ataatcgata ttgtgtttga tttatcaact
     7981 tttttcctat acaatgaaaa aggtagaaat gttattacgt aaatgaaaac tagaggtgta
     8041 aatatggcga atttggttta tagtcctaaa gacattttac aacaagaatt caaaacaaaa
     8101 atgcgcggct atgatcccgt tgaagttgat gaattcttag acaatatcat caaagattat
     8161 gaaacttaca gcaaagaact ccttgcttta caagaagaaa acgatcgatt gagtgcaaaa
     8221 gtagctcaat tatctaaaac tcaaggagca gctcaaacac gcgtgcaaca aacagaggca
     8281 ccaaagagcg cagcagtgac caattttgat atcttaaaac gcttgtcaaa tcttgaacgt
     8341 gaagtatttg gtaaaaagct tgatcaacaa gcaagtgcag tcaaaccagc acaacctaat
     8401 ccaaataact acacaaatgc agacacaagc ttagatgata atgaaaaaac acgtcaattt
     8461 taatttttga ttaatgaatt tgcggttttc gggtaatcgc ggtctgactt gatcaggctg
     8521 aggaaagtcc atgctcgcac aggctgtgat gcctgtagtg ttcgtgctta gcgaaaccat
     8581 aagctaaggt actctttgga gtaacggcag gaaaacaagc taaggcttcg gctatgctta
     8641 agtatccttg aaagtgccac agtgacgaag cggctgggga aacccatccg gtggaacgcg
     8701 gtaaacccct cgagcgagca acccaaacaa tggtaggggc gctttttgtc tggaagaaga
     8761 acaggacaaa aaggcagtat aactgcagat agatggttac cgctttgttt tttctccctg
     8821 gaaaagcaaa gtacagaaca tggcttatag aaaaccgcaa acatcaggga attaggtcgt
     8881 gacaaaagta atgcgttata agaaacaaga aaaacatttg aaagctattt ttcaatactt
     8941 cagatgaatc gttcttatta caaaacaaac ttttgtatca ccggttattc ggaatttgag
     9001 taaaagtgtg gggtaggact gatgtcccac ctcctttttt tataaataag gagattgtgt
     9061 atggaaaaaa acaggaagtt caacctcgtc gcaactgcgg caagcgggct agaagcactg
     9121 gttggtaaag aattaagaga tcttggaatc gaatgccaag ttgagaacgg acgtgcacgt
     9181 tttgaaggaa caatggaaac gatcgctaca gctaatttat ggttacgtac agcagatcga
     9241 gtaaaaatcg tggttgggga attcgatgcg tatacgtttg atgaattgtt tgaaaacgta
     9301 aaagcattgc cttgggaaga ttttcttcca ctagatgcag cttttcctgt agctggaaaa
     9361 tcgatcaagt cgaaactata tagcacacct gattgccaag cgatcacaaa aaaagcaatc
     9421 gttgaacgtc tccgtaccta ttatcaccgt ccagcttctg taccactgac ggaaactggc
     9481 gcacattttc agttggaagt agctttgctg aaagaccatg tgatggtaac tctggatacg
     9541 acaggaccaa gtttattcaa acgtggttat cgcttagaaa aaggtggagc accattgaaa
     9601 gaaaacatgg cagcagcact tattatgttg acaaattggc gaaaagaccg tccattttat
     9661 gatcctgtat gtggttcagg tacgctttgt attgaagcag ccttaatagg ccataatatc
     9721 gcaccaggat tcaatcgtga gtttgcttgc gaatcttggg attggttcag tcaagaaatc
     9781 atggaaaatg ttcgatcagc agccgaagaa aaagcagatt atgatattga attagatatt
     9841 actggttcag atatcaatgg acggatgatt gaaattgcca aagccaatgc agaagaaatc
     9901 ggattaggct cttcgattac ctttaagcaa caagcagtca aagacttcaa aacggataaa
     9961 gaatacgggg tcatcgtggc taatccgcct tacggagaac gtctaggaga agaagaaact
    10021 gttcggaaat tatataaaga aatgggcgat gtattccgtc cattaaaaac atggagtaaa
    10081 tatatcttga ctagcgactt agcgtttgag gaattttacg gacaaaaagc aaccaaaaaa
    10141 agaaaattgt acaatggtgc attgcgtacg gatctattcc agtattgggg aactcgtccg
    10201 cctagaaaaa aagagaaaga cgaataatct tactaattga ttcattcaat tggatgtttg
    10261 gaggaatagg gaatgaaaga aaaagagttt ttacaagaag taaaagaaat caatcttcta
    10321 caacaagctt taggaatcct cgattgggat acacaaacag gtatgcctga aaaagctagt
    10381 gcataccgaa gtgaagtaga cagctatctt tacagcattt atttttcaaa aaaaatcggt
    10441 ccaaaaatca aagaagccat tcgctatttt tctgaacatc cggaagaatt gtcggaagtt
    10501 ggaactgccg tttttgccaa agtaaaagaa gagtatgatt tggaacatcg cgtaccggaa
    10561 gatcttatga gaaaatatac agctgccgtt tcttcagcac acggacaatg gcaaaaagct
    10621 agagaaacac aacaattttc tgattttcaa cacgcattga atcaaaatat tgaattaaca
    10681 aaacagttga taccttactg gagaaaagat gaaaagacga attatgatgt tttgctgaat
    10741 caatacgaac ccgggatgac tgtcgaaatc cttgataagg tatttgatca gcttaaagaa
    10801 ggaattcttt cgatccgccg tacgctccaa gaaaaaggga ctgaacctga aacagacttt
    10861 ttaaatcgga gaatgacgaa aaaacaacag aagagatttg tagtgaaagt aatcgaacaa
    10921 cttggttatg attttagtcg tggtcgttta gatgacactg tccacccatt tatgactgga
    10981 attaatccga atgatgcacg aatcacgaca cgatggaacg aaacagattt caaaatggct
    11041 gtttttggag tgatccacga ggctggtcat ggtatgtatg aacaagacat cgatgataaa
    11101 tatgcgtata caccggttta tgaaggtaca tcaatgggta tccatgaatc acaatcgttg
    11161 tttaacgaga tcattattgg aagtagtcgc agcttctgga aaaagcaata tcctttcttt
    11221 caagaatgtg cagaaggaac attcgatgat attccttttg acaaatttta tcgttcattg
    11281 aaccatacaa aatcaagttt ggttcgtatc gaggcagaca gtttgactta ccctctccat
    11341 atcatcattc gttatgaaat cgaaaaaatg attttcaatg aaggggtaga tgttgctgaa
    11401 ctacctgaaa tatggaatca aaaatatgaa gagtatctgg gaatacgacc aacaaatgat
    11461 gtggaaggca tcctacaaga cgttcattgg tcaggtgcaa gctttggtta ttttccctct
    11521 tatgcattag ggtacatgta tgcggcacaa ttacttcatt ctttgcagca agaaatagat
    11581 gtggaaaatg ttctagcgtc agacgattat tctccaatca aaaactggat gtcagagcat
    11641 atccatcaat atggtgcatc tagaaaacca aatcaattaa tcatggatgc aacacatgaa
    11701 ccgcttaatc cgcaatacct gatcgactat atgaaagacc tgtattttaa tgtatatcag
    11761 gtaaaataaa atacaattta caaagatagc tgaaattcat ctaatctata gatgttttca
    11821 gctatttact taagaaagaa gtggaacgaa tggataaatt acaagtgatc gctgattata
    11881 gtatggacca attagcgcat gatcaaacag gacatgggag cgatcatacc aaaagagttg
    11941 tcaagttagc tgaaaaaatt ttggagacgg aaccgcaggc agaccgcttt gtgacgcttg
    12001 cagcagctta cctacatgat acgattgatg ataaagtcgt taaaaatgag aacgaggcaa
    12061 agcaacagct tcgtgtattc cttcgctctt tgccaatagt agaggaacag atctcgatga
    12121 ttttttccat tatcgaaaat atgtcctttt ctaaaaatct ctctgaagcg gccgaactat
    12181 ctctggaagg taagatcgtt caagacgctg atcgtatcga agcattagga gcaatcggca
    12241 ttttgcgtac tgcttatttc ggcggtggac atgggcaccc gatttttgat cctgaactgt
    12301 atccgcaaac attcaaggac aaagaaaatt accgaaaagg cacgacagtg atcaatcatt
    12361 tttatgaaaa actgttcttg ctgtctgata aaatgaatac tgattacgga tatgaagaag
    12421 ccaaacgaag agaaaccttc atgcgtgaat tcttagaaga attttttctg gaatggtcta
    12481 ttgacgatga aaattttact ccagacaatt ggatcaaaaa taacaaaaaa tgatggaggt
    12541 tgtgacagaa gtggtcagct ccaagatatt tcggatcatt ttccgtaaaa gttacttctg
    12601 gaacactgtt taccaagagg tcgtgagcct gccgttcagc tccgagtcac aaggaacaat
    12661 ttcaaaaaat agcttctcgt gtttgatgaa tattgtaact tgtgattcgg aattggcagg
    12721 agaacaccgt ttatt
//
LOCUS       DAIGWC010000077        12494 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.078, whole genome shotgun sequence.
ACCESSION   DAIGWC010000077 DAIGWC010000000
VERSION     DAIGWC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.078"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            158..730
                     /locus_tag="NOB74_002301"
     CDS             158..730
                     /locus_tag="NOB74_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HCI1221463.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            875..1579
                     /locus_tag="NOB74_002302"
     CDS             875..1579
                     /locus_tag="NOB74_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI1221464.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNSDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            1807..2145
                     /locus_tag="NOB74_002303"
     CDS             1807..2145
                     /locus_tag="NOB74_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221465.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2130..2984
                     /locus_tag="NOB74_002304"
     CDS             2130..2984
                     /locus_tag="NOB74_002304"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCI1221466.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3131..3364
                     /locus_tag="NOB74_002305"
     CDS             3131..3364
                     /locus_tag="NOB74_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HCI1221467.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3562..5466
                     /locus_tag="NOB74_002306"
     CDS             3562..5466
                     /locus_tag="NOB74_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI1221468.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            5776..6138
                     /locus_tag="NOB74_002307"
     CDS             5776..6138
                     /locus_tag="NOB74_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1221469.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            6155..6766
                     /locus_tag="NOB74_002308"
     CDS             6155..6766
                     /locus_tag="NOB74_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HCI1221470.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(6868..7776)
                     /locus_tag="NOB74_002309"
     CDS             complement(6868..7776)
                     /locus_tag="NOB74_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI1221471.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(7818..8132)
                     /locus_tag="NOB74_002310"
     CDS             complement(7818..8132)
                     /locus_tag="NOB74_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCI1221472.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            8431..10362
                     /locus_tag="NOB74_002311"
     CDS             8431..10362
                     /locus_tag="NOB74_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI1221473.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            10655..11206
                     /locus_tag="NOB74_002312"
     CDS             10655..11206
                     /locus_tag="NOB74_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI1221474.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            11519..12061
                     /locus_tag="NOB74_002313"
     CDS             11519..12061
                     /locus_tag="NOB74_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221475.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         4048 a         2092 c         2609 g         3745 t
ORIGIN      
        1 aatttaatag agaagcctgg cgtctattaa gaaataattt tcttgatgag cgtcaatttt
       61 tttaacggaa atctatccta tactaaattc agtaaagaaa aaggaggaat caaagaaagc
      121 tattttaaac aaaccaaaat tataggagga ataaatcatg actgaaaata aagctactca
      181 agaaagaaca ccccaagaaa gattgcaaga agaacaagaa cacaaggaac atgttcatca
      241 tacgaaaatt aatgcagcgg ccattgcgga tcatctttta ggcaacatgc atacattaca
      301 tgtgaaactg caccaatatc actggtatgt aaaaggagcc aatttcttta cgttgcatga
      361 aaaatttgaa gagttgtata acgaaaatga aaaatggttc gacaaacttg cggagcgtct
      421 aattacttct gggcataaac ctgcttcgac aacggttgaa tttgaaaaat attcgatgct
      481 ttcggaagat gcagttaata aatacgctaa agcagaagac atggttgaaa atattatcga
      541 ggacttcaga agcactcgtg acctaactat tcgcgcgatt cgtttagctc aagacgaggg
      601 tgacgatgct ttagaagata cattgattgc ttttaaaaat gacttagaca agaacatttg
      661 gatgctgcaa gcgttcattg gtaaagaagc attagaagat gatgacgctc ttgatgagga
      721 tgaagattaa ggtaaaagta gaagctgatt tagggattgg aattctttcc agtccttttt
      781 ccattttctt gatgtgcatc aatttttttg tagtaagaga cttatataat aaaagcagcg
      841 aatataaaca aaataaataa agggggagaa tgaattgact aaacataccc atcatgaaat
      901 tggcgaccac gcagcctgta tccgcttggt tccaatattc aatcacttag aggatagcgc
      961 gatgaattac attgctgaaa aagcccacac gaaacagtat caaaaaggag agtttctgtt
     1021 tcgttcacaa gaaaaagagg atactttata tattatcaat cgtgggaaaa tccgtattta
     1081 tcgattggca gactctggca aagagcagct agtgcggatc ttgaaccctg gtgatttcac
     1141 cggagaatgg accttgttca actcggatgc agtacacgag gaatatgccg aagcaacccg
     1201 agataccgtt gtctgtatga ttcagcaaaa agatgtccaa gattttctgg aacaataccc
     1261 agctatttct ttaaaactat tggcggaaat gtctaaacgg ttagaaagtt cagaacgtca
     1321 aacgacacaa gtagccgtgg agagtgtcat tacccgttta gttttgtttt tggcagaaaa
     1381 tgtggaacct gaaatgggca actctcccac catcaccctg ccgatggcaa aaaaggacat
     1441 tgcttcctat ttaggaacga cacctgagac catcagtcgc aaatttggag aattggagga
     1501 cgaaggattg attcaacagc tgtctgggaa aaggatcaag attcaggatt tagatgattt
     1561 attgctttac agcgaataat cggacacact tttttctaca cgttggtgtt ctgtcgctct
     1621 tcattaacaa cgggacagaa ctcagtgctt ttgcttccat ctgtccgttt ttggcttttt
     1681 taagacagaa cgaccttcat tcattggaaa aataaaagca caaacatgat aaccctcaag
     1741 tttttttgtt ttatttttct ttaagatagg gttgtcgaac aaaacgtaaa aataagtagg
     1801 gtgaatgtgc attgtttttg ggtgatagtt gccatcacgt tgtcagcagc gggggcattc
     1861 tttgtcgtcc ctttcaccaa gaacacgatt ggcggcgaag caaaaacgtc taacgttgtt
     1921 gaggcagata ggttagctat ggaaaaagaa gaggaagttg taaaaggagc cggcgtaatc
     1981 ggacacggaa aagtggcgta ttacgaagcg agtgaccagg gagataaaag tgtattcact
     2041 gtttggtttc catggagctt agccggaatc ttgttcagca tcaccatgac tagaatgacg
     2101 cgaaaaattg aagaaatgga gcaaatagaa tgggattcgt attaggcgtt ttgaatcccc
     2161 atgtggtgga gattggttct gttgtgattc attggtatgg agtcattatt gcagcgggca
     2221 tattagcggc tctccagttg agcaccaagg aagcaaagaa aaaaggactg gaagaggata
     2281 ccattatcga tatggcctta tgggcaattc cgattggact cctcggcgct cggctttatt
     2341 atgtgttatt tgaacttggt tattatctgc aaaatccagg acaaatcctt gcgatttgga
     2401 atggcggcat tgcgatttat gggggattga ttgcaggagg gggtacgcta tattggtatg
     2461 caaagaaaaa aggtacttct ttggcactcg ttcttgatat tttagcgccc aatgtattgt
     2521 tagcccagtc cattggtcgt tggggcaatt ttatgaatca ggaagctcat ggtgggccgg
     2581 ttactcgtca attcttggaa aatctttatt tacctgaatt tatcattgaa caaatgaata
     2641 tgaatggtac ctactaccat ccgacttttt tatacgagtc attgtggagt ttgttgggct
     2701 ttgtcctcat cgtcactata cggaaccgaa aacagctttt gcgtcaagga gaagtcgctt
     2761 tgagttacgt tttgtggtac tcagtgggtc ggttcttcat tgaaggtatg cgaacggaca
     2821 gtttatggat tggcgagtgg atccgcgttt cgcaagcctt gtctctggcc ctgtttattg
     2881 gcgcgattgt agtatggttt atacgcagac aagattatcc accaatttct tattattctg
     2941 atggcaataa ggggcagaaa aagactatta agatggtgaa ttgagcaaaa agataaaaag
     3001 aagtgcaaaa cttgatatgc gtcaattttc gtttgctaaa agtgagctat actacagttg
     3061 taaagaggaa aaggcagtgt tcattaatct gctgccgata aaataaaaac acataaagga
     3121 gataggaatt atggaaaaag ctatattgca attagaaacg ttgtcttgtc caagttgtat
     3181 gcaaaaaatt gaaggtgccg tgaaatcagt taacggtatt gataaagaca gcattaaagt
     3241 attattcaac tccagcaaag tcaaaaccaa ttttgattca gctgtcactt cgattgaaga
     3301 gattcaaaaa gctatcgaaa acgtaggcta tccggttctt aaagcaaaag tcaaggccgt
     3361 ttaacagatt aaatgaacta ggcaattctg gaagaaaagc tatttttcca ggattgcttt
     3421 ttttgttgca atccgattcg aggtgcttag aaacgataaa agagaacttt ctaaacttga
     3481 tgtcagtcaa ttaattactt aggcaattat cttatactgt gtttatcaat aaaagagaaa
     3541 ttaaatttgg agggaaaaag catgcaacaa tatatattaa gcaagaaaaa tgttatcacc
     3601 gtcatcagtg gattgttaat cgtactcggt ttcttcagtc actttgtttt agaaaacgta
     3661 ggactttcag agtggtcttt gatcatcgcc tctgtctttg ggattacgcc aattgccatt
     3721 caagcgtttc aagcaatgaa agtcaaagtc atcagtattg atgtcttagt cagtattgca
     3781 gcgattggtg cgctttttat tcaaaattat gaagaatcgg ctattgtcac gttcttattc
     3841 ttattcggac actacttgga acaacgaaca ttgaaccaaa cgcgatctgc tatcaaagaa
     3901 ttgactgaaa tggcacccga aagcgccttg aaacaaatgg ataatggcga atttgaagaa
     3961 gtagaagtgg atgatataga tgaaggggat atcttgctcg ttaaaacggg tgcgaaagtt
     4021 ccagtagatg gcatagtcct tacgggtgaa gggcatatca atgaagctag cattacaggt
     4081 gaagctattc cggtcaacaa gctagctgat gcagaagttt ttgcaggaac cattttagaa
     4141 aacggaacga ttcaaatcag agctgaccga gttggtgagg acaccacatt tggaaaaatt
     4201 attgaactcg tggaagaagc acaagattct aaatccgaag cggaacggtt cattgatcgc
     4261 ttttctaaat actacacacc agctgtcttg gttctggcaa ttgttgtatg ggcgttcagt
     4321 caaaatattg agttagcaat caccatcttg gttctaggtt gcccaggcgc attagttatc
     4381 ggagtgcctg tctcaaacgt tgccggtatt gggaatggtg ctcgtaacgg tgttctttta
     4441 aaagggagtg aagtcattca agacttcagt aatgtggata caattgtatt tgataagaca
     4501 ggtactttaa ctgtcggaaa cccaaccgtt gcagcgactg aactgtatga aaaagatcct
     4561 gctgaaacgc ttggctatct ggccagtgtg gaacgggaat cagatcatcc attagcaaaa
     4621 gcggtcttaa atcaaattgg agaaacaaac ttttatcctg ttgaaggaac tgaagttgtg
     4681 aaaggcggcg gaatcgtttc aagtgtagct ggacatagag tggctgttgg gaatgtggcc
     4741 ttgatggaaa aagaaaatgt cactctcagc aaaaaagtgc aaaaagatgt caaacggttt
     4801 gaacaacaag ggaactctct cgttttgaca gcggtcgacg gtgaattaaa agtactgatg
     4861 ggcattcgcg atcaagtccg tccgggtgtg aaagctaatt tgcaggaatt aaaagacttg
     4921 ggcgtgaaaa atctagtcgt tctttcagga gataaccaag gaaccgttga tgtggtcgcc
     4981 ggcgaacttg gtttgaccga agctcacggc tacatgttgc cggaagacaa atcggcttat
     5041 atcggaaaac ttcaacaacg tggtcaaatt gtagcctttg ttggagatgg cgttaacgat
     5101 agtccgtcct tagctttagc agacattgga atcgcaatgg gaagcggaac ggacgtagcg
     5161 attgaaacat ccgatgtcgt tttaatgaac tcgaacttca gcaacttgcc tcacgcatta
     5221 ggattagtaa aagccaccgc aaataatatg aaacaaaata tcgtgatttc aattggagta
     5281 gtgttggtct tgttgaccag cgtcttcttc agcgaatgga tgaatatgtc tatcggaatg
     5341 ttggttcatg aaggtagtat cttggtggta attttcaatg gcatgagatt aatgaagtat
     5401 aagttgaaag gtcgaaaaga acaaaaagaa gtatcagcac ctgcagagaa agtaaaaata
     5461 tcttaagaat aaattagaag aggctgagac aatagtccat ccttgaaatg acaaaagcgg
     5521 aaactcagat ttttaaatct gggattttcc gcttttttga gttcttgaaa aaaaataaga
     5581 gtatagagta tgttctttat aaaattaatt ttcgtgtaaa tgattaaaaa atttaataat
     5641 aaaatttaaa ttcctattaa gttgtaacac atgaaattgc ttataatagt gtattgaaat
     5701 taaggtagat tgacaaacga gtgatcaaat agatatacta ccttcaaacg accgtttgaa
     5761 tgtgaggtga gatgaatgga aaaagtttgc caagtgacta tcgtacataa agaaaaagta
     5821 aatgtaataa aaaaaaaatt ggatcaaaaa gatttttcaa acttacttgt gttagggaaa
     5881 tgtttcagcg attcttctag gattaaaatt ttctatgctt tagaaaccta taaggaaatg
     5941 tgtgtctgtg atttagcaga aatacttact gctagtgtcg ctacaacgtc acaccattta
     6001 cgttttttaa aaaaacatgg aatggcaaaa tcacgtcaag atggaaaagt agtttattat
     6061 tctttagcga atgaagacat cctttccgct attcgtgttt ttttaaagtt atcagaaaat
     6121 ctatctatga aatcttagtt tggaggaagt tattttgtta caaagtattt tttcagctat
     6181 cgctgtttat atttctacca gtattgatta tttgtttatc ttgctgatta tcttttctca
     6241 aagccacaca aaaaaaggta ttcgtcacat tttttggggt caatatcttg gaacaggtat
     6301 tttggtagcc gtaagtttgt ttgctgctta tgtgctaaat tttattccgc aagattggat
     6361 cattggtctt ctcggtctaa ttccgatttt cttaggaatc agagtcgctt ttgttggcga
     6421 agaggaggaa gaagaagagg aagtcgttga aaaactcgaa tctagaggaa ctaatcgctt
     6481 attctggaca gttgccttaa taacgattgc ttctggaggc gataatttag gtatttatat
     6541 tccatacttt acctcgttag ctttttcaga aatcattatt gctttaatcg tattcgctat
     6601 ctctgttgcg gttctctgct atatcagtta caaattagcc aagatttctt ttgtttccga
     6661 aacgttagaa aaatacgaac gaatcattgt ccctataatg tttattgcgt taggaatttt
     6721 tattatgata gagaacggga cgatacaaac gctactaggt ttttaaaaat cataatcacg
     6781 aaagataaaa agagaggcag cgactaatca aaatcgctgc cttttttgct tttcaaataa
     6841 tgaagtattt tttagcgtag aactatctta cgtgttgtgg gagtatccct tttcaagctc
     6901 ttctttgctt gtagttattt ctattgtgat atgattctct acgcttgatt tgtgtgcgac
     6961 ttctgcaatt tcttctttta tttccctagc cttgtctatg tctgaagggt ctataagaac
     7021 cgtgatgata agggcgtttt cttccccgtc cagtgaccaa atgtgaaaat gtgagaggtc
     7081 ttttacagca ggaacatttt taatggagtc cgccaagctc tttacgttta cattttcagg
     7141 cgaaccattc aataaaattt tcattgtggt gaaaaattca ggaacggttt tgtagaggat
     7201 ataaagtgca atcaaaatcg ataagatagg atccagacga tatgcctcgg taaagttcat
     7261 tagaatactc acaatcaaga ctccaatcca ccctaatacg tcttccagca tatggaggtt
     7321 caacatgctc tcgtttttgg atgtgccttt gcttaaaatc cacgcagcat atccattcaa
     7381 tgcaatagct acgagagaaa gccagaacat gccactataa tttacgggtt gtgggtcaat
     7441 caaacgtggc acactacgat agatcataaa aaacgagcca ctaattagca caacgccagt
     7501 tatcagcgcg cccagtaaag aaaagcggtt atagccaaaa gtgaaccgtt catcttgttt
     7561 tttctctgaa taaccttgaa aaaaccaagc gaatccaatt gaaatagagt cccctaaatc
     7621 atgaactgcg tcggacataa tggacacact attgaaaaga aagccaaaga aaaattcgct
     7681 tatagagaaa ataagattta tgaagaaagc aattttaata ttctttttcg gttgattctg
     7741 attcgagtga ttatggtctt tatctgattt tgacatttaa aaacctccta agtttgtatg
     7801 ctacatacta attggtttta tttttctaat tcattaacat gagttaagac ttgttcgaga
     7861 atactaaaaa catgaaggtc atctaaactg taaagcatac tttttccttc tcttcttgat
     7921 ttcactaagc gtgcgtcttt caacgttttt aattgatgag aaatagcgga ctgttccatg
     7981 tccagagaaa tagcgatatt tccaacacta cactcttttt tctgtaaaag aaagagaacc
     8041 gacaatcgtg taggatcact aatcacctta aatagtttgc ttattgacag aatagatcct
     8101 ttatcgattg gagaagttgt ttttatatcc atagtgtttt tattcctttc atatgacctt
     8161 ccgttcatat ctatattacc atatgagcga aacaatgcta atcttttgtt tataaaagag
     8221 aagtggcgtt ctctttatct tgacaaaatg tatatagcga tataaaatga gtatacaaac
     8281 atatgattaa ttagtcatat gtaaggtgga ttcattacga tttacttttg gaataaacga
     8341 aaggagtcag aaatagcaga aatttatgtg attcaagaag taaatgatgg aaaacaaagg
     8401 aattataaat tatataggga ggcaatagaa gtggaaacta tccaagaaca acagtctcaa
     8461 gaaaagcata atcataatca caaccacgat cacgaccatg atcatgggaa aatgccagtc
     8521 gttttgtact ttgttggttt agcattagca gtgattgctc tatttttgaa tgaagattat
     8581 cagttggtac aaaatgtttt gttctcaatc gctacaatca gtgccgggta tcacgttatt
     8641 cttcttgaag gccttggaga aacaattgag aattcaaaag cacaaaaaaa gttcatacct
     8701 aattctcata ttttaatggg attagcggca attggagctt ctttgatggg gaatttttgg
     8761 gaaggaacat tattgattct tattttttct ggcgcacatt ttttggaaga ttatgcagaa
     8821 ggaagaagca aacgagaaat aacgaaatta ctcgaaatga atccaacgac tgcccggtta
     8881 atcctgcctg atggtagtac aaaaaatgtg gatgtcagtg aattaaaagt gggagatcaa
     8941 cttcaagtgt tgaatggcga tcaagtacct attgatggcg tcattttgtc tggatctaca
     9001 tccattgatg agtcgtctat tactggagaa agtatcccga aagagaaatc caaaggagat
     9061 ggcgtcttcg ggagtacaat caatggaaca ggtaccttca cgatgaaagt caccaaagaa
     9121 aacaaagata cagtattttc aaaaatttta caattagtga atcagaacca agataaccaa
     9181 acaaaagctg cgagtattat ccaaaaattt gaaccgaaat atgtcacagt tgttttaatt
     9241 gccattcctc tattcatgtt attggctcct tttctacttg attggacatg gtcacaaagt
     9301 gtctatagag gattggtcct tttagttgca gcttcaccgt gtgctttagc agcagctact
     9361 gtctcggcaa cgctatcgac gacttctaat ttagccaaaa aaggagtcct ttcaaaaggt
     9421 agttcttacc tgtctcaatt agccgatatt aaagcaattg catttgataa gacgggcacc
     9481 ttgaccaaag gaaaacctga agtaaccaat tattattttg ctgattccgt gaacgaagaa
     9541 aacatgattg atatcgtagt agctcttgaa aaagaatcca atcacccctt agcagatgct
     9601 attctaagaa agtttgagca aaaaaacaaa ctaactattg aagtagaaaa ccaaattggt
     9661 aaaggattga cgggagatta caaagggaga aattatcgta taggaaaacc gacttcgttt
     9721 gatgatgttt cagatgaata tagtcgttta aataatgaat gggcgtcaga aggtaagaca
     9781 gtcgtatacg tagcagtaga tgaagaggtt ataggcctta ttgcccttat ggacgttccg
     9841 agtgaatatg ctaaagaaac cattgaatat tttaggaaac aaggtataca caccacatta
     9901 attactggtg actcagaaat gacgggaaaa gcggttgcta aacaattagg aatagatgaa
     9961 gtgattgcga atgtcatgcc ggaagacaaa tccagaatta tagacgaaca aaaagaaaaa
    10021 tacggcgtga ccgccatggt tggagacggt gtaaatgatg ctcctgctct tgttaatgca
    10081 gatgtgggaa tcgctatggg agatgggact gatgtggcag tagaggtatc tgatttagtt
    10141 ttaatgcaaa acaatttatc taaattggta caatctcata atatttcttc gaaaatgaac
    10201 cgtgttattt ggcagaatat tattttttca atggccgttg ttgctttttt aattgtcgtt
    10261 agtttcttag gcttaacgga tattgcaatc agtgtcatta ttcatgaagg aagtactttg
    10321 gttgttattt tgaatggact tcgattgcta aaggcagtct aaagaatgat tgcacaactt
    10381 caaattaatc gagtaataga gataattaag gattacacta cattttttat ctctattact
    10441 tgtttatatt tatctagatg ttcaaagtca aaatgatata tcaaccatac tcttgtggcg
    10501 cgggttgaat ataagataca tgaaattgga taaaatcatg tatcaagaat cctatcctta
    10561 tagggttctt tttttttact ccccctaaac acacgatttc gtgttgtaat aactataatc
    10621 atgtattcga acagactaaa aaggagggat tgtcatgggc tataatgttc agccactacg
    10681 gtcgcaacag gagattaatg attttttatt ttgcctgcga cggaataaaa atgcggaacg
    10741 tgacgttttc ttgtttctaa ttggaattaa cagcggtctg cgcatgtccg acatcgttaa
    10801 actcaagaaa aaagacgtga ttacctcaaa aaacccgcgc atcgtggagc aaaagacagg
    10861 gaaaacacgc attttatact taagcagctt acaggacttg attcacggct ataccgcacc
    10921 cttagatccg gaggcttact tgtttcccag tactaagggc ggccatttag aagtcaatac
    10981 ggtctaccag atgtttcaaa aggtcgcgaa gctgttagga agggacgata tcggcaccca
    11041 caccctacga aaaacctttg gttaccacta ttacaagaaa accaaagacg tggccacctt
    11101 aatggaaatc tttggtcaca gcagcgagaa gattaccaaa cgctacatcg gaattaatga
    11161 agatgaaatc agtgaaacgt tattaaattt tcggttaggt ttttgattgt attatataat
    11221 agataagcac agtaagacgg ttataatcac ccacagtatt ggacaaatca accttttttt
    11281 ggtatattat atatacaaat gagagcaggc tcatagtcaa cttgatataa atccggaaca
    11341 taagggtccg gcgggtggcg agcaccaaaa ctaaactcga tacaaatccg gaacgtaagg
    11401 gtccggcggg tggcaagcac caaaactaaa cctgtacaaa aggctgctct tttgagcagc
    11461 tttttttatt gggaaaaagg agcattcttc gcacgcggca aaaaaagaat acaaacgcat
    11521 gtctataaaa gagacaaccc aaattaccag acagttaaac gcgatttata aggctgctca
    11581 tctcttacaa gaacattttg tagataaaaa agtatccttt gtcggagaag tctcaacggt
    11641 agcgattatt ttttcgacaa ctaattttat gcacctctgt ggcattgatt atcgcagagg
    11701 cacacacttg ttttttcaag atgccttaga caggaaaata aatttacagg atattcaaat
    11761 caaaacggat gggacgacct ttcagaaatt acaagtaata ggtagccttg atttattatt
    11821 ggggaagcat atttctattg ttggcagagg tgtttactct tctcttcgct atgatgcagc
    11881 tattcgaaca aggaaaaaaa tattggctct gtctttgaaa caaaacggat taatctatat
    11941 ccctatctct ttgttaaacc tatcatcaaa ggaaattgga cctggacaaa aagttactgg
    12001 catttttagc gaggatttaa catccgggga acttaaaatg attatggaag tcatcgatta
    12061 atcattaata gtgatatgcg acgtcatttt gaagtaatta ttctattttg ggttataaaa
    12121 taaagcattt taagacgatt tcaaatcatt catgtgggtt atttatcacg gatgagcttg
    12181 aaatcgtctt ttatacgtat caaattgaaa tgttcggcat acaacctatc gttgttacta
    12241 cattactaat tgtcacttgt taaggaactt ggatcctttc taaacattcc ctagagataa
    12301 attttacttt atccctccgt taatatccaa tttaagcacc tttccgattc agggttaatt
    12361 tgcatatcaa gtgcagcttg tgttctagta agattagccc ttttagtccg gctgagttga
    12421 cttatggata taagatatgg tcatagcaaa tagatactac gtatagtctg ttaatttagt
    12481 gtcattaatc ttaa
//
LOCUS       DAIGWC010000078        12236 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.079, whole genome shotgun sequence.
ACCESSION   DAIGWC010000078 DAIGWC010000000
VERSION     DAIGWC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.079"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            134..1066
                     /locus_tag="NOB74_002314"
     CDS             134..1066
                     /locus_tag="NOB74_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HCI1221476.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1138..2259
                     /locus_tag="NOB74_002315"
     CDS             1138..2259
                     /locus_tag="NOB74_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1221477.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(2341..4113)
                     /locus_tag="NOB74_002316"
     CDS             complement(2341..4113)
                     /locus_tag="NOB74_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221478.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(4116..5828)
                     /locus_tag="NOB74_002317"
     CDS             complement(4116..5828)
                     /locus_tag="NOB74_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221479.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            5943..6611
                     /locus_tag="NOB74_002318"
     CDS             5943..6611
                     /locus_tag="NOB74_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HCI1221480.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMA
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            complement(6678..7466)
                     /locus_tag="NOB74_002319"
     CDS             complement(6678..7466)
                     /locus_tag="NOB74_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HCI1221481.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMASTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(7549..9021)
                     /locus_tag="NOB74_002320"
     CDS             complement(7549..9021)
                     /locus_tag="NOB74_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1221482.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            complement(9151..10344)
                     /locus_tag="NOB74_002321"
     CDS             complement(9151..10344)
                     /locus_tag="NOB74_002321"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HCI1221483.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     regulatory      complement(10342..10421)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            complement(10610..10681)
                     /locus_tag="NOB74_002322"
     tRNA            complement(10610..10681)
                     /locus_tag="NOB74_002322"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10646..10648),aa:Glu,seq:ttc)
     gene            complement(10693..10766)
                     /locus_tag="NOB74_002323"
     tRNA            complement(10693..10766)
                     /locus_tag="NOB74_002323"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10730..10732),aa:Ile,seq:gat)
     gene            complement(10779..10849)
                     /locus_tag="NOB74_002324"
     tRNA            complement(10779..10849)
                     /locus_tag="NOB74_002324"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10815..10817),aa:Gly,seq:tcc)
     gene            complement(10854..10926)
                     /locus_tag="NOB74_002325"
     tRNA            complement(10854..10926)
                     /locus_tag="NOB74_002325"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10891..10893),aa:Phe,seq:gaa)
     gene            complement(10930..11002)
                     /locus_tag="NOB74_002326"
     tRNA            complement(10930..11002)
                     /locus_tag="NOB74_002326"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10967..10969),aa:Asp,seq:gtc)
     gene            complement(11021..11094)
                     /locus_tag="NOB74_002327"
     tRNA            complement(11021..11094)
                     /locus_tag="NOB74_002327"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11058..11060),aa:Met,seq:cat)
     gene            complement(11107..11196)
                     /locus_tag="NOB74_002328"
     tRNA            complement(11107..11196)
                     /locus_tag="NOB74_002328"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11158..11160),aa:Ser,seq:tga)
     gene            complement(11219..11290)
                     /locus_tag="NOB74_002329"
     tRNA            complement(11219..11290)
                     /locus_tag="NOB74_002329"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11255..11257),aa:Glu,seq:ttc)
     gene            complement(11312..11399)
                     /locus_tag="NOB74_002330"
     tRNA            complement(11312..11399)
                     /locus_tag="NOB74_002330"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11363..11365),aa:Ser,seq:gct)
     gene            complement(11424..11497)
                     /locus_tag="NOB74_002331"
     tRNA            complement(11424..11497)
                     /locus_tag="NOB74_002331"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11461..11463),aa:Ile,seq:gat)
     gene            complement(11511..11581)
                     /locus_tag="NOB74_002332"
     tRNA            complement(11511..11581)
                     /locus_tag="NOB74_002332"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11547..11549),aa:Gly,seq:tcc)
     gene            complement(11583..11658)
                     /locus_tag="NOB74_002333"
     tRNA            complement(11583..11658)
                     /locus_tag="NOB74_002333"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11623..11625),aa:Asp,seq:gtc)
     gene            complement(11677..11750)
                     /locus_tag="NOB74_002334"
     tRNA            complement(11677..11750)
                     /locus_tag="NOB74_002334"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11714..11716),aa:Met,seq:cat)
     gene            complement(11763..11852)
                     /locus_tag="NOB74_002335"
     tRNA            complement(11763..11852)
                     /locus_tag="NOB74_002335"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11814..11816),aa:Ser,seq:tga)
     gene            complement(11876..11949)
                     /locus_tag="NOB74_002336"
     tRNA            complement(11876..11949)
                     /locus_tag="NOB74_002336"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11913..11915),aa:Ile,seq:cat)
     gene            complement(11963..12036)
                     /locus_tag="NOB74_002337"
     tRNA            complement(11963..12036)
                     /locus_tag="NOB74_002337"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12000..12002),aa:Met,seq:cat)
     gene            complement(12064..12136)
                     /locus_tag="NOB74_002338"
     tRNA            complement(12064..12136)
                     /locus_tag="NOB74_002338"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12101..12103),aa:Ala,seq:tgc)
     gene            complement(12156..12229)
                     /locus_tag="NOB74_002339"
     tRNA            complement(12156..12229)
                     /locus_tag="NOB74_002339"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12193..12195),aa:Pro,seq:tgg)
BASE COUNT         3998 a         2557 c         2113 g         3568 t
ORIGIN      
        1 aaaaaaagag aaagaagatt taaatgatga aataaatcaa aagtatgatg aaacattaaa
       61 aaatgtctat tcttcactta tcgtttcaaa tatagaagaa acttcatctt ctgaaataaa
      121 aaataagctt tctttgttaa aattaaaaga aaaggaatat attattgacg atgctgtttc
      181 tgtccctctt attttaaata aacgagagaa aaataattta aagaaaaaaa tgctcattcc
      241 atttgattca gaagtgaaag gattactcaa taaactaact atttctaata tagactcgac
      301 tagggaaaaa atcataaaaa tatttgataa aattaataat ttattcaaga atgacaatgc
      361 tgaattaagg aagggtcttt tagagtttaa acttcaagaa ctagaacttc attactctta
      421 tttagtgaaa attaccgaag aaaaagaaca acaaaaagca ataaaagaac agatgataga
      481 agaggaaaaa gttcgtagag aaattgatcg tgaaaagaaa cgtattgata aagaacaacg
      541 tcaattcaat tctgaaattt ccaaattaat cgcatatatg caaaaagcta atgcagatgt
      601 ggaaaaagaa ttatatgcaa ataaaattca agaactggaa gaaaaattaa aagaattaga
      661 agttatacgt gaaaatgtat tacaaagaga attaaatact agagccggtt atgtgtatgt
      721 aattagtaat attgggtctt ttggtgaaga catatataaa attggtatga ctagaagatt
      781 agaacctatg gatagaataa aagaattgag tagtgcatcg gttccatttg aatttgacgt
      841 tcatgcgatg attttttcag aggacgctcc gtctttggaa actaaattgc ataatcattt
      901 tagaaaacaa gaagttaata aaattaatca aagaaaagaa tttttcaaag tttcactaga
      961 cgaaatagag aaagttgttt tagaaaatta taatggaaca gtaacattta caaaattagc
     1021 taaagctgaa caatatagac gatctttaga attgtcaaaa gattaaatat ataaaaagcc
     1081 ttcgggcttt ttcttttaac aattaatagg aacgtatatt cgaaaggaat agaaataatg
     1141 tggttagaaa aaataaatga caaaaaattt aagtacaccg aacgttatac ggatccctta
     1201 actgaaaaaa agagaaaagt gtccgttact ttatctagca attcacgcca agcttggaat
     1261 caagctaact tacttttgaa tgaaaaaatc gcagaaaaaa taaaacgaaa tgaagaatta
     1321 ccactaactt ttggagaatt aaaaactaaa tgggatgaaa aatacaagcc aactgtaaaa
     1381 gaaagttcct atcgaacaac tcaggtttat ctatcattaa tttcaaaata tataaaagat
     1441 gatgtacttg taaaaaacgt taatagtaat cttatacaag atatgctaga ttactactat
     1501 tttgaaaaaa atttatcata taattatgta atacatttaa aaacttttac aggaatgatt
     1561 tttaaattcg ccaaccgtcg atatggatta aaatataatc ccgtaaatgg ggtttcttta
     1621 gcaagaaaac ctaagacaaa cgaagaaata aaaaaagaaa aagatggtta tttatcaaaa
     1681 gaagaagttc aaatgattgc tagtaaacaa aaaagttcac atcaacagtc acgttattct
     1741 ttaattacta aatttttgtt tttaactgga ctacgttatg gtgaattgat atctttgact
     1801 gaatctgatt atgatggtaa taaaattacg gtttctggta cttatgatta cgagttaaaa
     1861 attaaaacaa caactaaaaa tacaggttct tatagaacca ttgaattatc aagtaatgct
     1921 aaagaaatca tagatcaatt aattgaagaa aacaaattaa ttaagaataa taaagataaa
     1981 tacattttca tctctaaaaa tggtaacccg atatctattc aagcatataa tcaatcttta
     2041 agagcagtat ccaaagaatt aaacctagat aaaaaagttt cttctcacat gttaaggcat
     2101 tcccacattt ctctacttac agaattagga atcccattaa aagccattat ggatcgtgta
     2161 ggacatgaag attcaaaaac aacattaaag atttatactc atacaactaa aaatatgcaa
     2221 aatcaactag tagaaaaact aggaaaaata gaaatttaaa ttgccccttt tctgcccctt
     2281 ataaaaacaa acaacataaa atatataaaa agaaccccgt tataacgagg ttcttttaat
     2341 ttaactttca aatacaaatt gattatgata aagttccgca taaaatccat tttctgctaa
     2401 taactcatga tgactgcctt cttcaatgac ttccccatca cgcaagacaa cgattctatc
     2461 tgcattcaag attgttttca gccggtgagc aatcacaaag ctggttcttc ctttgattgc
     2521 ttcatccatt gctttttgga tccttgcttc tgttaccgtg tctacattac ttgttgcttc
     2581 atccaaaatc aataaagatg gatttgtgat gatcgttcga gcaatactga tcaactgctt
     2641 ttgacctgta ctgaataagt tattttcttc ggatatctct gtatcataac ctttttctaa
     2701 cgtcatgatg aagtcatgaa tattcgcttg ttttgctgca ttgatgactt cttcatctga
     2761 agcgtccggt ttgccgaatg tgatattgtc tttgatcgtt ccggagaaca atacagattc
     2821 ttgcaaaacg attcctacat gtctacgtaa tgcatcaaga tcataatctc ggatatctat
     2881 tccatcgatg actactgaac catcattgac atcgtaaaaa cggtttagca gattcatgat
     2941 cgtcgttttc cccgatcctg ttggaccaac aagagcaacc atttctcctt tgtccacatt
     3001 gatcgagaca tctttcaaga ctagtttttc tggagaataa ccaaaatcta cgtgctgcaa
     3061 cgcaagacct ttttcaacac catcaaatgc tttaccgttt tctggtttga cttcatcttt
     3121 ttcatcaaat atttcattca atcgtcttgc ccctgtaatc gctaattgga tcatgctgta
     3181 tccagatgaa atctgcatca gtggttggta atattgttgt gaatactgga cgaatgtcac
     3241 aactaagcct aatgccaccg aacgttccaa atcaccattt aatgctaacc agccgccgaa
     3301 aaagataact atcgctgtat tgaccagtga cattccttgc atcatcggaa atagtagacc
     3361 agaataagct tgtcctttga aggttgcttc gcgaacactt tgattatgct ctaagaatcc
     3421 ttcaatcgtt tcttcttgta agccatttgt gatgatgaca cgttgtccgc tgattttttc
     3481 atccatataa ccatttagtt tccccacttc atcttgctga agatccacat atttccgtgc
     3541 tttgcggata atcaagacag ctatcaaaac ggctactgga gtggaagcaa ttgtagccca
     3601 agctaactct acattttggc ggaacatcat gatcaagatc ccgacaagta aaacagcatt
     3661 cgtgatgact tgaagcaaag cttggttcaa actattttga atattatcta agtcactggt
     3721 aaaacgactt aaaatttcac cgtcttgatg agaatcaaag aaacggatcg tcaatttttc
     3781 caatttgttg aatagaccga tacgcattcg gttcgttgac ttccctacta cttgtgtgaa
     3841 caaaatacta tagataaagt tggctgcact agctagtaca taaaacagca agagtttcca
     3901 tattacagaa acaaatttgc ttttatcgtc tacgccttgc atcaagcctc ctacgtaatt
     3961 agctaattct tgaaaagctt ccccgatgta ttgaggtgcc tttacttgta gataggtagc
     4021 aatgatcact gtgataaaga taaagaaaaa ggagagtttg taccgcttca aatagtgata
     4081 gaaaaattta cttgctttta ttagatcagt catacttact cctccgttcc tttttgagtt
     4141 tcaaagattt cctgatagac acggtttcca gctaccaatt cctcatgggt tccttcgccg
     4201 actaatctgc cttcatccaa tactaagatg cggtctgctt tgacaacaga agcaattttt
     4261 tgtgcgatga caatcgtcgt tgttcccttc aaatctcgat cgagtgcttc tcggaccagc
     4321 ttttcagagc gagcatccag tgcactcgta ctgtcatcta ggatcaagat ctttggatta
     4381 ccgataacgc cacgagtaat ggataaacgt tgcttttgac caccagaaaa gttactgcta
     4441 cgttcttcta ttggtgcttc gtaacgatca gataactttt cgatgaattc ttttgcttga
     4501 gcaatagaag aagcatgttc catctctttt tctgttgcat tctttttccc ttggcgcaag
     4561 ttttgagcaa tcgttcctga gaataaaatt gctttttgca aaacaaagga aaccgtttgt
     4621 cttaaactct tttcatttac ttgacgaaga tctacaccac ctacttcaac tttgccttct
     4681 gtcggatcaa atagacgagg gatcaattgt gctagtgttg acttcccggc accagtcgcc
     4741 ccgacgatac caaccatttc tccaggtttg atagaaaagc tgatatcttt aagcgtatct
     4801 gtatcctcac caggataacg aaaagaaaca tggtcaaaag tgacagaacc cgtcaactct
     4861 tgttctggaa cgtctaaata agtaagatct ggttcagcat ctaaaatttc cgcaatccgc
     4921 ttcagcgata cggctgctct tgaagtcatc atcatcatca ttccgccaat aatgattgcc
     4981 atcataatct gcatcaagta gttcatgaat gaagcaattc caccaattaa cgtaggatca
     5041 tctttaacaa gatcgctcac aaaaaagatc gccccaacca cagccaaatt ggcagccagc
     5101 atgaaggacg ggatcatcac agaaaataat gtaccgacta tgatgttgtg ttttgttaag
     5161 tcctcactta ctttgctgaa tgacttcaat tggttttctt cttgtacaaa agatttcact
     5221 acacgaatcc ctagtaagtt ttcttttgca atgctattca cacgatcaat cagtttttga
     5281 atgatcatga agtgcttgcc catccttgta aatgaaagtg ccgtaatcag aaataccgta
     5341 acgataagcg ctacgatgat ccaccataat tgcggcatcg tgatcatagc taaaatgaag
     5401 gcaccaataa ataagaatgg aattcgaaaa agtgattgca aagaaatcat cactaaattt
     5461 tggatttgcg tgatatcatt tgttagacga acaacaagat ttccagcaga gaactgttcg
     5521 atatttccaa atgaaaatgt ctggatcttt cgaaatgctt cttctcggat atctgcactt
     5581 acgccttgag ctacttttgc agagaaaatc gtgttcgtta cacctgcggc taatcctagc
     5641 aaagccagac tgatcaggta aataccaatt gttttcattt catcattatc ttctgtaata
     5701 atagcttcca atacttgctg tagtaactta ggttgccata atgctgctgc aaccatgact
     5761 gctacggaca gcaaggaaat aaaaacagat actttatatt ttttcgcatg tcgtaagatt
     5821 aatttcattc gttgattaca cccctttgtt taaattgaca ggactaattt aacactgtaa
     5881 aattagaccg actaacaatt taccatgttt aaaaagataa tgcaatacac gaggttgata
     5941 aaatggaaat aaagctttct caagcaatca tcattcaggc cgcctttgat atcctggctg
     6001 aaacacaagc tctttcgcag ctttccatgc gaaacatcgc aaacagaatt catgttcaag
     6061 cacctgcttt atattggtat ttcaaaaaca aacaacagct cttgcaaaaa atggctgaaa
     6121 caatggaaga agaattagcg cttccagatc caactttgcc ttggaatgaa cagttgctgc
     6181 agtatatgga aaattactat gacctttata cacgtttccc ttgtggggca gaattagaaa
     6241 tcaatactgt gcccgctttt ccgagtcgat tagaacattt ggagcaaatg atccaattac
     6301 ttgttcgtga aggattttca gtcacccaaa gtcatcaggc cattgcctct ctccacaatt
     6361 tattgattgg acagttaatg gatcagcagc atgaacagca gcttcgacaa aaaattatgg
     6421 ccggaaatga atttttgaaa gaaacagttc tatttatgcg taattatgta gttgaaaatc
     6481 aattagaggg atttaaagaa agtatgcagt cccatgcaga attgaatgaa aaagcactct
     6541 ttctaacgag tgcacaaacc tatattgaag gcttatgcca acaaaataaa agaagagaaa
     6601 acgagcagta aaaaagctcc tatagagatc actatgtttg tgatctctat aggagctatc
     6661 tttttaagac tcttttttta tttttcttcc attagccacg ccaatgcacg ttgaatccat
     6721 tggtcccaga agatccagtt atgatcgcca ggtccttgtt caaaggtgac cgccaagcct
     6781 tgttcctgca tagcagatac catttcctga tttgcctgat aaagaaaatc agattcccca
     6841 caagccatat aaaatcttgg aactggtttt ccgcttttta ctagttcttt caataagtat
     6901 tgcggatcat tttttgaacc ttcgatttga tccaatggtc caaagatccc ttcccaaaaa
     6961 gatgctttac gaaccatcaa aagatcatcc attcgatttc ctacagaaac agcgcctgaa
     7021 agagagatta ctgctgcgaa attttctgat tttgcaaggc ctagttttaa cgcgccatat
     7081 ccgcccatcg ataatccagc ggcatatgtt ttttctcttt ttcttgttaa ttgcgggaat
     7141 aattcatgac aaatctcagg tagctcttct gcaatgaatg tccaatactt catgtcataa
     7201 actgtatctg tgtaccagcc aagatcagta gatgccatga tgacagctaa tccgtagttt
     7261 gctacataac gttcaatcga cgtacgtctt tcccatacac tatgattgcc acccattcca
     7321 tgaagtaaat ataaaacagg tatatccgtt gtctcttgct ctgaactggt gccaatcacc
     7381 ttttttgttg tttgcggtag tatcacattt agattgactt ccatttctaa cacattcgaa
     7441 taaatatttg cttgaataaa tgccatattt tcgccttcct tagtaagaag ttatttttga
     7501 ataactttaa atttgaatga ttcggctacg tacatatctt aaccgaaact actgttttat
     7561 tttaccactt ttttcatgaa cgaaaagcgt taagaccaaa gcaatgatca cgagtaacaa
     7621 gccaactaga taaacggaat gtaacccatc ataaagaatt tttcttaatg gtaacaaaat
     7681 atccgcatca atatatttag ccgtttgtgg attcaccagt ttattcatga tatctgcatc
     7741 atttgttaaa tttgctgctg caagttctcg tttagttacc ccatttatca ataaaccaaa
     7801 aatagaaacc atgactgttt gaccaattgt tcgaactaac gtattaaaag aagttgctac
     7861 accaagctgg tcacgagata cactattttg tgcactgaca gtcgaggtag tcatggtcac
     7921 acctaagcct ataccgatga ccgttgatat agcaaaaaac cataaatagt tacttctgaa
     7981 aggcataaga tacaaccaag cgcccccaat agctgcgatt agtagtccaa ttctcaagac
     8041 ccaatgagtt ttcatttgag tcatccactt gcttgcaagg aaagaaccga ccatccagac
     8101 tagtgataat ggtgctaata ccagcccacc aattgctgca ttcagcccta atacaccttg
     8161 catccacata gggatataaa catcgattcc catcaaaaaa ccactagcca atgctgcagc
     8221 caagttgacc acaacaaata gtggattttt gaataaatgc atcatgatga caggatcttt
     8281 agctcttttt tcggcaaaaa caaaaatacc taacattacg atactaccta gcagcaaagc
     8341 agaaacaagc ggactcattc cttcgtctcc taataattgg aaccctaaca gcaatgagac
     8401 aagcatggcc atcaaactaa aactaccaaa aatatccatt ggtttagact catgtatgat
     8461 ttttggttca tttaaatata gccaaatcaa aataattaat agaattccga tcggcacatt
     8521 gataaaaaag atccagtgcc agctgatcgt ttcaacgatg aatcctcccg caagcggtcc
     8581 aaaaacactg gcaatccccc aggctgaact attcaaacct aaaacttttg ctcgcttttc
     8641 aatagaataa agatcgccga tgatcgtcaa agctactggc atcattgccc cagcacccat
     8701 cccttgaatc gcacgagcag caatcaaccc aatcatgctt tgagataaac cgcaaaataa
     8761 cgaaccgata ataaacaata atgtcccaaa aataaagatt ggtttccgtc ccactttatc
     8821 cgcaagtttt ccgtaaatcg gagtaagcat agcgtttgtc agcaaataaa tcgaaaatac
     8881 ccagttcatg atttccattc catgtaatga accgacaatc gttggcatag cggttgttac
     8941 gattgtacct tcaatagccg tcatgaacgt tgcaatgaaa atactcactg tgaccaaagt
     9001 aacatttgtt tcttttttca tcttattcct ccctttcatt atgacaggat ctaaaaatag
     9061 ataaataatt actatctttt tcaagaggtt aactgccata aaaaaagctg gaacaaccac
     9121 cacttggcga tcgttccagc tgaatataac ttattttgct aaacttgctt tcaacgcatc
     9181 tactttgtcc gtatgttccc aaggcaaatc tacatctgta cgaccaaaat gaccgtaagc
     9241 agctgtttgt ttgtaaatcg gacgacgcaa atcaagcatc tcgatgattc ctgctggccg
     9301 aagatcgaag ttttctctca ctgcagcaat cagttcttct tccggaaccg ttccagtacc
     9361 gaaagtattg attgagatcg aaacaggttg agcaacacca atcgcataag ctagctgtac
     9421 ttctgctttg cgagcaagcc ctgctgcaac aatgttttta gcaatataac gtgcagcata
     9481 gctggcagaa cggtcaactt ttgtcgcatc tttaccagaa aaagcaccgc caccatgacg
     9541 agcataaccg ccatacgtat caacaatgat ttttcttcct gttaatccgg catccccttg
     9601 aggaccacca atgacaaatc ggccagtcgg attgatataa tatttcgttt gatcatctaa
     9661 taattcagct ggaataactt ccttcactac tttttcgatg acatcatgac gaattgtttc
     9721 attatctact gcatcatcat gctgtgttga aataacgatt gtatctacgc gttccggttg
     9781 tccttgatca tcatattcaa ccgttacttg agattttgca tctggacgta aatacgttaa
     9841 ttcatttgat ttacgcaaat ctgccaagcg tcgtaccaga cgatgactca aagcgattgg
     9901 taaaggcatc aattctggtg tttcatctac agcaaaccca aacattaaac cttggtcacc
     9961 agcaccaatc tcatctaata cgtctttttt atcttcatcc cggatctcaa gtgcttcatc
    10021 aactccttga gcaatatcag gagattgttc atcaatcgca accaatacag ctgctgtatc
    10081 tccatcaaat ccgaattttg cacgtgtata accaatttct tttattgttt cccgtacgac
    10141 tttttgaata tctacatatg ccgtcgtaga tatttctcca aatactaaaa caagaccagt
    10201 tgttacagac gtttcacacg ctactcgtgc tgttggatct tgttttaaaa ttgcatccaa
    10261 gattgcatca ctgatttggt cagcaatttt atctggatgt ccttcagaaa cagattctga
    10321 tgtaaataag tgtctttcta ccattataat gattccccct agttaaattc ggttacaagg
    10381 catctccgtc ctgcggatcc tttcgggaac ttgcaacgaa ccaagtatag cagataaaac
    10441 agttttctgc tcgtattttt tcattttttt gcttaaaaaa tataaaaata ttttacatta
    10501 gaactgtcca aaaaagctta gcacaatcat ccataaagat aactctgcta agctttttaa
    10561 aatcattctt tcagataaaa agaaaaagat actcaaaaag tatcttccat gacccgtacg
    10621 ggattcgaac ccgtgttacc gccgtgaaag ggcggtgtct taaccgcttg accaacgggc
    10681 caataaaata aatgggccta aatggactcg aaccatcgac ctcacgctta tcaggcgtgc
    10741 gctctaacca gctgagctat aggcccataa aaactaaaag cgggtgacga gaatcgaact
    10801 cgcgacaaca gcttggaagg ctgtggtttt accactaaac tacacccgca taatggcgcg
    10861 ggacagaatc gaactgccga cacatggagc ttcaatccat tgctctacca actgagctac
    10921 cgagccaaac ggttccgacg ggaatcgaac ccgcgatctc ctgcgtgaca ggcaggcatg
    10981 ttaaccccta caccacggaa ccaatgtttt tagtttttaa ttgcgggagc aggatttgaa
    11041 cctacgacct tcgggttatg agcccgacga gctaccagac tgctccatcc cgcgataata
    11101 tgaaaaagga ggataaggga ttcgaaccct tgcacggttt tacccgcctg acggttttca
    11161 agaccgttcc cttcagccgg acttgggtaa tcctccatgt aaaactatat taaattaatg
    11221 acccgtacgg gattcgaacc cgtgttaccg ccgtgaaagg gcggtgtctt aaccgcttga
    11281 ccaacgggcc aggtaaaaca aaatattgaa acggagaagg agggatttga accctcgcgc
    11341 cggtttcccg acctacaccc ttagcagggg cgcctcttca gccacttgag tacttcccca
    11401 aaaccaataa gattttgtac taatgggcct aaatggactc gaaccatcga cctcacgctt
    11461 atcaggcgtg cgctctaacc agctgagcta taggcccata aaaaactaaa agcgggtgac
    11521 gagaatcgaa ctcgcgacaa cagcttggaa ggctgtggtt ttaccactaa actacacccg
    11581 catggcggtt ccgacgggaa tcgaacccgc gatctcctgc gtgacaggca ggcatgttaa
    11641 cccctacacc acggaaccag tgtttttagt ttttaattgc gggagcagga tttgaaccta
    11701 cgaccttcgg gttatgagcc cgacgagcta ccagactgct ccatcccgcg ataatatgaa
    11761 aaaggaggat aagggattcg aacccttgca cggttttacc cgcctgacgg ttttcaagac
    11821 cgttcccttc agccggactt gggtaatcct ccatatgaaa cttacaacgc cacaatggac
    11881 cttgtaggac tcgaacctac gaccggacgg ttatgagccg tctgctctaa ccaactgagc
    11941 taaaggtcca ggctcttaaa aatcgcggcg gaggggatcg aacccccgac ctcccgggta
    12001 tgaaccggac gctctagcca gctgagctac accgcgaaaa agatattcat tatttaaatg
    12061 aaatggagcc tagcgggatc gaaccgctga cctcctgcgt gcaaagcagg cgctctccca
    12121 gctgagctaa ggccccgtgt ttaaatttat aattatcggg aagacaggat tcgaacctgc
    12181 gaccccttgg tcccaaacca agtgctctac caagctgagc tacttcccgt ttaatt
//
LOCUS       DAIGWC010000079        12176 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.080, whole genome shotgun sequence.
ACCESSION   DAIGWC010000079 DAIGWC010000000
VERSION     DAIGWC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.080"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(59..616)
                     /gene="frr"
                     /locus_tag="NOB74_002340"
     CDS             complement(59..616)
                     /gene="frr"
                     /locus_tag="NOB74_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HCI1221484.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(619..1341)
                     /locus_tag="NOB74_002341"
     CDS             complement(619..1341)
                     /locus_tag="NOB74_002341"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HCI1221485.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1477..2358)
                     /locus_tag="NOB74_002342"
     CDS             complement(1477..2358)
                     /locus_tag="NOB74_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HCI1221486.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2457..3239)
                     /gene="rpsB"
                     /locus_tag="NOB74_002343"
     CDS             complement(2457..3239)
                     /gene="rpsB"
                     /locus_tag="NOB74_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HCI1221487.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3598..4077
                     /locus_tag="NOB74_002344"
     CDS             3598..4077
                     /locus_tag="NOB74_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HCI1221488.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4294..5385
                     /gene="phnW"
                     /locus_tag="NOB74_002345"
     CDS             4294..5385
                     /gene="phnW"
                     /locus_tag="NOB74_002345"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HCI1221489.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5378..5506
                     /locus_tag="NOB74_002346"
     CDS             5378..5506
                     /locus_tag="NOB74_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCI1221490.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5510..6055
                     /locus_tag="NOB74_002347"
     CDS             5510..6055
                     /locus_tag="NOB74_002347"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCI1221491.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6509..8200)
                     /locus_tag="NOB74_002348"
     CDS             complement(6509..8200)
                     /locus_tag="NOB74_002348"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HCI1221492.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8620..9567)
                     /gene="arcC"
                     /locus_tag="NOB74_002349"
     CDS             complement(8620..9567)
                     /gene="arcC"
                     /locus_tag="NOB74_002349"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HCI1221493.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9682..10701)
                     /gene="argF"
                     /locus_tag="NOB74_002350"
     CDS             complement(9682..10701)
                     /gene="argF"
                     /locus_tag="NOB74_002350"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCI1221494.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10792..12021)
                     /gene="arcA"
                     /locus_tag="NOB74_002351"
     CDS             complement(10792..12021)
                     /gene="arcA"
                     /locus_tag="NOB74_002351"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HCI1221495.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3332 a         2527 c         2202 g         4115 t
ORIGIN      
        1 aaatataaat aaaaacagag gaagcggaat gatccgcccc tctgttttta tgattttatt
       61 aaacttccaa taattctttt tctttatcag cagcgatctt atctacttct ttgatgctgt
      121 tatctgtcaa tgtttgtacg tctttttcta atccgcgcaa atcatcttcg gtaatatcac
      181 catttttttg ttgtttttta tattcatcga tcgcatcacg acggatgtta cgaatcgcga
      241 tttttgcatt ttctgcttct tttttaacat ctttagctaa ttcttttctg cgttcttctg
      301 tcagttgcgg gataactaag cgaatgacat ttccatcatt ggttggactg attccgatat
      361 cacttgccat aatagctttt tcaacatctt gaagaatgct cttgtcaaaa ggtgtgatca
      421 ttaaaacacg tgcttctgga atttggattg atgccatttg gttcaatggt gttggcgcac
      481 cgtagtagtt cacagtaata cggtccaaaa ggctagcgtt cgcacggcct gcgcggattt
      541 gcccaagttc acgttgaaga ttttgtgctg cttttttcat tttttctttt gcttctgtca
      601 taattgcatc tgccattttt atttccccct tacagttgtt ccgatatttt cgcctaagat
      661 tgcacggcga atatttccgt gttcatttaa attgaagaca agcagtggaa tatcattatc
      721 catgcttagt gaacttgcag ttgaatccat gacttgtaat cctttggcaa taacttccag
      781 atgagtcagt tcttcaaatt ttactgcatt tgcatctact ttcggatcag cagaataaac
      841 accgtctaca ttgtttttag ccatcaggat aacatctgcg ccgatttctg ccgcgcgtaa
      901 tgctgctgtt gtgtctgtcg agaagtacgg gttgccggta ccgcctgcaa agataacgat
      961 ccgtcctttt tctaaatgac gttctgcttt acggcgaata tatggctctg cgatttgacg
     1021 catttcaatc gaagtttgca cgcgtgtcgg tacacccacg ttttccaacg tatcctgtaa
     1081 agctaaggca ttcataactg tagctaacat acccatgtaa tcagcttgag cacgttccat
     1141 gcccatttgt gctccgattt gtccgcgcca gatatttccg ccgcccacaa cgattgccat
     1201 ttcaacgccc agctcgtgaa cttctttgat ttcttggatg atttctttga ttactggtgg
     1261 tttgattcca aatcctgcgt ccccagctaa agcttctcca ctcaatttta agactacacg
     1321 ctgatatttc ggtgtgacca tgttcattcc tccaatattt tctattgcca ttttaccata
     1381 cttagatgat ttcgacactc taagactggt ttttcttgtt ttgcttaaaa aaagggagcg
     1441 cacaaaccgt gcgttcccgt ctgttattca acagaattat tttttcactt ggctcataac
     1501 ttcttctaca aagttatctt cgcgtttttc gataccttcg ccaacttcga aacgtacgaa
     1561 tgttttaaca gttgcgcctt ttgatgcaac gtatttttca acagtcatat caggatcttt
     1621 aacgaatggt tggtccacca aagcgatttc tgctttgaat ttcttcaagc gtccttctac
     1681 cattttttca acgatattcg ctggtttgcc ttcgttcaat gcttgttctg taagaacagt
     1741 tttttcatgt tctaattcag cttctggaat ttgtgattcg tttacataac gaggattgat
     1801 agctgctacg tgcatagcta cgtctcttgc aactgtttcg tcagttgttc catctagaac
     1861 agtcaatacg gcaatacgtc cgcccatatg caagtatcca ccaaatgcag cattgtcgtc
     1921 tttttctaca acttcaaagc gacggaagct gattttttct ccgataactt gagttgcttc
     1981 gatcaagtca gattcaattg tacctttatc tgttttgatt ttcattgcag cttccatgtc
     2041 tgctggtttg ttttcagcaa caagttctgc aatttctttt actaaatctt ggaacatttc
     2101 gtttttagaa acaaagtctg tttctgagtt tacttcaacg attgctgcag tgttaccttt
     2161 cacagcaact gaagccaatc cttcagctgc aatgcggtca tttttcttcg cagcctttgc
     2221 cattcctttt tcacgtaaaa gatcaactgc tttttccatg tcgccttcta cttcaactaa
     2281 tgcttttttc gcatccatca ttcctacgcc agtcatttcg cgtagttctt ttaccatttt
     2341 agctgtaacg tctgccatgt ttaactcctc ctgtgtgttt ttctttttaa aaaaagctgc
     2401 ttcaaaggag agtgaggctt gtcgcccagc ctttgaaaca gctccatcat tcaaaattat
     2461 tctgctgaag aattgtcgcc ttcaacaaca tctacgattt cttcgattga tgttgctgtg
     2521 ttttcttctg tgaaatcttc ttcaactact tgatcttcac cttggtttcc ttcgatgaaa
     2581 gcatcagcca tttttgaagt aatcaattta acggcacgaa ttgcatcgtc gtttgaaggg
     2641 attactacgt cgatttcatc tggatcgcag tttgtatcaa ccatagctac gattgggata
     2701 tttaatttgt gtgcttcttg aacagcaata cgttctttac gtgggtcaac gatgtacatt
     2761 acatctggga ttcttggcat atcagcgata ccgcctaaga atttttcaag acgttcacgt
     2821 tctttgttca aaccagcaac ttctttttta ggtagaactt caaaagttcc atcttcttcc
     2881 attgcattga tttgtttcaa acggctgata cgtttttgga tagtatccca gtttgtcaat
     2941 gttccgccta accaacgatg gttaacgaag tattgtcctg cacgagttgc ttcttctttg
     3001 attgcttctt gtgcttgttt ttttgtacct acgaataatg ctacgccgcc ttcttcagca
     3061 acgctcttca tgtaatcata agctgcatct actaatttaa ctgttttttg caagtcaatg
     3121 atgtagattc cgtttctttc tgtgaagata tatttcttca tttttggatt ccagcgacga
     3181 gtttggtgac caaagtgtac gccggcttct agtaattgtt tcatagaaat tactgccatg
     3241 tttgtttcct ccgatttggt tttatttttc ctcttcttat cttctacctt gccggcaaac
     3301 tttttcaagc acctaccgac aatccaataa gaatgtggat ttgctgatgc ataaagcacc
     3361 ctcagctatt atacagacaa aagatccgta tcgcaagagc aaatatactt ttctgctcaa
     3421 cattcaatag tttacctgaa agataaaaag aattcaagaa aaacagtaga tttctctttg
     3481 tttctttatt atcctttttc cataaaataa ttttaggtat aaaagacgaa tattattggg
     3541 caatccttct tttttttgtt atgatacatg tgaaatcttt cgtaaaggag aaagaaaatg
     3601 cgcaaagctc aaagacattt gctgattaaa caagtcattg aagaattccc gatccgtacg
     3661 caagaagaac tattaaacaa acttgggcat tatggcgtta ccgccacgca ggcaacgatt
     3721 tctcgagata tccgtgatct aaaaatcgtg aaggcacctg atgaaaatgg cgtttcccgc
     3781 ttcgtattgt ttcgcgaaaa aggaactcct gagactagga ctgaggaaga ggatcggctg
     3841 gttcaaatga ttgaagacat tgtattgaaa gtcgaacgag tccacttttt gacgatcgtc
     3901 aataccttgc cagacaatgc tcatttattt gcatctgttt tagatgagat caaacctccc
     3961 tctattgtca gtacaattgc tggattcgat acgatcatgg tcatctcgga aaatgaggag
     4021 gacgcaaaac gagtagaaga atttcttcac catccaactg aagtatcact tttttaatca
     4081 gagcacgtat tcctaatatg gaatgcgtgt ttttttattt tcaatatttt ccttattgaa
     4141 taaaccttta cactctttac aaaaatacat cattttttat tcaaattttt caacaccttg
     4201 attgaatcac aataatcatc atttatattg gatgttaaca agagcagctt cttgctcttt
     4261 gtgtatttca aaaaagaaat gaaaggaaat catatgtata aattattaac ttctggacca
     4321 ttgacgactt ctgaaacagt gaaaaatgct atgctgatcg atcattgtac ttgggatcaa
     4381 gaatacaaag aaattacaca atggataaga aaaaaattat tggatcttgc tcaagtatcg
     4441 gaaggaatat acacaacggt cttaatgcaa ggtagcagct ccttcggggt agaatcggta
     4501 ttaagttctg tgatcaggcc agaagatact gtactgattt gttcaaacgg cgcatataga
     4561 caacgaatga tcaacatgtg cgaatgtctg aaactgaact ataccgttta tgaggtatcg
     4621 gaacatcaaa tcctccaagc tcatgtgatt acacagctga ttgaagagaa tccgtctatc
     4681 tccgcactag caatggtcca tagcgagact acttccggta ttttgaataa tttggaagag
     4741 attgctgctg tcacacaaga aagagatctt ttgtttatag tggacgcgat gtcaagcttt
     4801 ggtgggatac cgatttgtgt agccgaacta gggattgatt ttttgatttc cagctcaaac
     4861 aaatgtattc aaggtgttcc aggcttttct tttgtacttg ctaataaagc ggaactggaa
     4921 aaacgaaaaa atgttagccg aagtttgtca cttgatctat atgaccagta ccgcgtgatg
     4981 gaaaacgaga atggcaaatg gcgtttcact tcccctaccc atacggtttt ggcttttcaa
     5041 caagcgctga aggaactaga ggcagaagga ggaatcgaaa ctcgatattc acgttatctc
     5101 gccaataatc atgtgctacg acaaaaaatg acagagatgg ggttccagcc tttcattcaa
     5161 gaatatcagg ggccattcat cacctctttt ctttacccta aggactggcg atttgatttt
     5221 aatcattttt atcagtattt aaagcaaaat ggatttgtga tctatcccgg gaaaatcagc
     5281 gatcatgaat gttttcgtat cggaaatatt ggcgagatct atccggaaga tattttggaa
     5341 ctgacagcaa ttatcaaaga ctataaggag aacgttaatg attaaaactg taatttttga
     5401 ttgggcagga acaactgtgg actttggctg tatggctcct gtccacgctt ttagaaatgc
     5461 ttttctagaa aaaggaatcc aactgactga caaagaaatc cgctaaccga tgggaaaatt
     5521 aaaatgggat catatccaac agcttctttc cctcccttct gtcaaaaaac aatggatagc
     5581 tatttatgga caactacctc aggaaaaaga ggtggaggaa ttgtatcaac aatttgaaca
     5641 ttatctgttt aaagatttgg tcaagcattc taccttgaaa cccgacacat tggaaacgat
     5701 cgaacggttg agaaacgctg ggatcaatat tggttccacg aatggattta atgctcctat
     5761 gatgacaatc gtagcagaaa ccgcaaaaaa agaaaggtat tcaccagact tcatggcaac
     5821 ttttgaagac gtcgaagggt atggtcgacc gtttccttat atgatccata aaaacatgca
     5881 gtacttcaaa aacaagtcgg ttgatgaagt aatcaaagtc ggagatacgg tctcagatat
     5941 ccaggaaggg aaaaatgccg gagtgttgac agtaggtgta attgaaggta gttcgctaat
     6001 ggggatttct tatgatgagt accaaaaatt agagatgggg aaaaagatcg tttaaaacag
     6061 tctgttgctc ttagattcca acaagccggc gctgatattt gtgtaaacaa tttaaaagag
     6121 ttaacagaat acattttgta cgctgacatg aatccagaat gacttttata caaaataaga
     6181 ggttgtgaaa aagctgtcct gtatcaagta ataaaaacag ccaagcaaaa atagctcctc
     6241 atatttttcg tttggttagg cttattaccg cagatgcaag cttttgaaca ccgtttattc
     6301 gaaaaaaaaa agggagctgt gacacgactt ttgtcacagt ccccttattt gcaaacaaac
     6361 agtgtttaag agacaacctc tccactaaac ggtgttcatt cagctgactc tcggtatttg
     6421 ctcaaaaaac gataaaattt gaaaagctat tttctctttt gtttctctaa tactcggatc
     6481 agaacgctga tttcacattc tctttttctt acatcttatc tggtgcatga agtcctagca
     6541 aacgaaggtc ttctttcaat aatacagtca ctgcataaac tagagctaag cgtgcttctt
     6601 tttgttcatc atcagctaaa atcttcgtat gagcatagta tttgttgaat gcttgtgcta
     6661 atttgattgc atgtttcgca atcactgacg gttcgtattt ttccccagca gacaagaccg
     6721 tttcagggta tttttgaact aatttaacca cttcccagct ggtatcgtca ttcaatgcat
     6781 agtctgctgt ttctgaaggg acaaatcctg ctttttccaa caggctgact gcacgagcat
     6841 gtgtatattg cacataaggt ccagtttctc cttcaaatcg aacaacttct tccaggttaa
     6901 agtcaaatgt attcagtcga tcgtttttca aatcgtggaa aatgactgcc ccaaccccaa
     6961 cttgtttagc tacagcatct ttgttttcca aatcagggtt tttctcgctg atttgttctt
     7021 tagcagattg gattgcttca tttaatactt cttctaataa gacgatcttt cctttacgag
     7081 ttgataattt tttaccacct tgcgtgatca aaccaaatgg aatatggtgc atgtcgtcag
     7141 accagtcaaa gcccatttcc ttcaagacag ctttcaactg tttaaaatga tagctttgtt
     7201 cattccctac tacatataga gattgtttga agtcgtaagt acgtttacgg tacaatgcag
     7261 cagctaagtc acgtgtaatg tatagtgtcg caccgtctga cttcttaatc aacgctggat
     7321 tcaggtcata agcagatagg tcaacgatct ctgcaccttt atcctcgttc agcaaatgtt
     7381 tttcttctaa aagtttgacg atttcatcca tcttgtcatt gtagaaagct tcaccgttca
     7441 acgaatcgaa acgtacttcc agcagatcat agattttatt gaattctttc atcgattcat
     7501 cacggaacca ttgccataat tgaatagcct ctttatcgcc ttcttccaga cgtttgaacc
     7561 aagcacgagc ttcttcattt aattctggtt ctgtttcagc tacttcatgg aattggacgt
     7621 ataaacgaag caattcattg attggttctg ctttaacagc ttcttctgta ccccattttt
     7681 tgtaagcgac gatcagtttt ccaaactgtg ttccccagtc acctaaatgg ttgatgcgga
     7741 ttggctgata accgattttt tccataatga aaccgatcga attaccgata actgtcgaac
     7801 gcaaatgtcc cattgagatt ggtttggcaa tattaggaga agacatgtcg attggtactg
     7861 ttccttgatt cccgatgttg ctatccccat aatgttcttt ttctttcact actgtttgca
     7921 aaactttttt gctgataagt tctttattca tgaaaaagtt caagtaaggt ccgacaactt
     7981 cgattttttc aaagttggca gaatcgattt tttctgctaa atctgcagcg atttgctgtg
     8041 gcgcttttcg gtaaactttt gctaatgaaa aggctggaaa tgcaacatct ccgtgttcag
     8101 ctgattttgg attttctagt aattgctcga cttgttccag tgttaaatca tctttgacag
     8161 cgtcatagac agcttttgcg acaagatctt tattattcat ctttattcct cctaaagtgt
     8221 tcccttgatt gttaaacaaa aaaaatctct agcgacggca tacttagtat gccatcacta
     8281 gagacgagat ttcccgcggt accactccaa ttgtcctaaa aaaggaccag ctccatctga
     8341 tatcggtaga cgaccgtctg tttaaaacag aattctccaa gtgcgcttcg ttgtatcttc
     8401 ttcattcggc ttccaccact tccgaattcg ctagccaaga atgatacaag tactctcttg
     8461 ttcaacaaat cttagtctta ttaaactttc ttgaattata tcagaaaaaa aaacgaaagg
     8521 ctagtcgttt cataaaaaaa caatccagat ggcctaaagg agaagaaata ccacctggat
     8581 agctataaat catttcgtaa atacgaaaga cttaacaaat taatcagcta cgataatcgt
     8641 tccttcttca gaagctaaaa gattctcgat attttctaaa gaagtgatga ttgccttagc
     8701 gtttggtttt gcttcaacaa atgcaatagc tgcttctact ttcggaagca tgcttcctgg
     8761 agcgaattgc ttttcatcaa tgtattgttt catttctgaa acagtaacag tttctaattt
     8821 cttttgatct ggtttttggt aattgacata cacattgtct actcctgtca atacgatcag
     8881 caaatccgca tcgatgattt cggctaattt ttctgaagca aaatctttat cgattacggc
     8941 ttctcgtcct tctaatccag tagctgtttc tacaacagga atcccaccgc caccaacaga
     9001 gactgtgata actccttgat cgaccagcgt ttcgatgaca cgtgcttctt taatcgagat
     9061 gggtttaggg gaagcgacta cttttctcca tccacgtcca gcatcttctt tgaatgtcac
     9121 agtggagtca gcattcattt gttctttggc ttcttcttcc gtgtagaatg gaccgactgg
     9181 tttacttgga tttttgaatg aaggatcatt ttcatccaca ataacttgag tgactaaaga
     9241 aaccacatct ttatcgatcc ctttttcctt cagtacttcg cccatggcgt tttgtaacca
     9301 gtaaccgata gatccttctg tcattgcaac acatgtatct aaaggcattg ccggtgtttt
     9361 ctcagaatca gcagcttgct gctgaatcaa taggttaccg acttgcggac catttccgtg
     9421 ggagatgatc aattcatctc cttgttcgat aaatttcact aaatactttg ctgtttccat
     9481 taacgcttct tgttgggctt ttgcacttgc atccgtagac aagatggcat tgccccctaa
     9541 agcgacaact acttttcgtt tggccatttc attcgtcctt tcttcagttc taccgaattt
     9601 tctagataac aaaacgagcc agcgttttgt gattttccct caatgctgac tcgttttttc
     9661 gtgagatgaa tgtggttatg cttaaacgcg agggataaac aagttaccta atgttgctgc
     9721 catgatcgct ttgattgagt gcatacgatt ttctgcttgg tcaaattgac gagcatattt
     9781 gctgcggaag acttcatctg ttacttccat ttcagtgatg ccaaagcgtt ctttcatttg
     9841 ttcaccgtaa acagtgtttg tatcatggaa agctggcaag cagtgcaaga agatcaaacg
     9901 atctgtgttg tgtgtttttt ctaccatttc catattgatt tggtaaggtt tcaacaattt
     9961 gatacgttct tcgaatttat cttcttcacc cattgatacc catacatcag aataaaggac
    10021 gtctgctccg tctacacctt tatcaacatc gtcggtaatc atcaattgtg caccggattt
    10081 ttcagcaaag ccttctgcca ttttgacgat ttcttcttca ggttgtaatt cttttggtgc
    10141 aacgatacgc atattcgctc ctaaaattgc acctgtgact aataaagagt tagccatatt
    10201 gtttcgacca tctccgcagt aagcaacagt gataccttct actgttccaa agttttcttg
    10261 gatagttaaa aagtcagcga tcatttgtgt tggatgccat tcatcagtca agccattcca
    10321 aactggaaca ccagagaatt ctgctagttc ctctaccatt ttttgactga atccacggaa
    10381 ttcgattccg tcaaacatac gtcctagtac tttagctgta tcttctgtgg attctttttt
    10441 acctaattgg atatcatttg cacctagata ttcaggatgt gcacctagat cgatcgctgc
    10501 agtagtaaat gcagaacgag tacgtgtaga tgttttttca aataaaagcg caatattttt
    10561 tccttctaga tagtgatgtg ggataccacg ttttttcaag tctttcaagt gttctgaaaa
    10621 atcgatcaaa tattgtaatt cttcttttgt aaagtctttt tctgctaata agcttcttcc
    10681 ttggaatact gattctttca tattaaacat tctcctttag attgttttta tttaagatta
    10741 aagaggaaat cccgacggca gctgacagta agactgccgt caggaaacaa attacttcaa
    10801 gtcttcacgg acaagtggtt ggctcatgca gcgtggacca ccacgacctc gtgacaattc
    10861 acttgaattg atttctaaca ctttgatgcc atagctacga agcaattcgt tcgatacata
    10921 atttcggtta taagtgacta caacacctgg agcgattgcc aatgtgtttg atccatcatt
    10981 ccattgttct cgaggtgcaa cgatctcatc tccattacca gttgggatca gtacaagatc
    11041 atctaatcca agagcagctt tcatcgtttc gtgtaagtta tctgaatgag taatcttgat
    11101 atcatcacca tctggttcga ttgtaaagac atccatctta ccgtctttac tttgaattgc
    11161 tggatggata gtgaatttat cgtgatctac cattgtaaat acggtatcca aatgcatcat
    11221 tgcacggttg ttcggaattt tgattgccaa cactttttca aatcctgaat tttttgcgaa
    11281 taggtggcgt gctaattttt ctaaagcttt cgcattagtt cgttgagaaa tcccaacagc
    11341 tactacttta tcgcttaaga tcaattcgtc tccgccttcg atatgatctg gattttcacg
    11401 atccaaccat acttcgattc ctttatttgc aaatcttgga tgatgtttca aaatatattc
    11461 tgtaaacatc gattcacgac gacgtgcttc aaaagtcatc ttattgactg tcatcccatt
    11521 tcccattgat gcggaagggt cgcgtgtaaa gtacaagttt ggcattgggt ccatgtaaaa
    11581 tggatagtca tcgtctgctg acagatcata tagactgcta gaacgtactt cgatatcttt
    11641 tgtacgaacc ccagccatga ttttatctac catttcttgc gtttccattg atagaaggaa
    11701 ctcatgaaga ccctctctta cagcattcga tgcaatatga gattcatcca acattttatt
    11761 caagaattgt tctttgacat tgcctgcgtc aatcgcttct gccgctaatt tttccaagta
    11821 aagagtctcg acgccttcat tttgcaatgt cttcgcaaag ttgtcatgtt cttcttgagc
    11881 aatcggaaga tatggaatat catcgaacaa cagacgatcc ataatatctg gtgtcaaatt
    11941 ttccacttct tgtccaggcc gtttcagtaa aactgtcttt aatttcccta tttcagagaa
    12001 aacgtgaata ggtttatcca tgttgtgttg cctccttctt tttgattaca tgtataggat
    12061 atcctccttt tgtaatcact ttcataattt tgtctcattc aaaatgagac attcctcaca
    12121 ttaatattcg ataattaaat aattaaacgt ttttctattt ttaagcgtaa tttatt
//
LOCUS       DAIGWC010000080        12146 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.081, whole genome shotgun sequence.
ACCESSION   DAIGWC010000080 DAIGWC010000000
VERSION     DAIGWC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.081"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(108..272)
                     /locus_tag="NOB74_002352"
     CDS             complement(108..272)
                     /locus_tag="NOB74_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221496.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            567..1895
                     /locus_tag="NOB74_002353"
     CDS             567..1895
                     /locus_tag="NOB74_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HCI1221497.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2097..2930
                     /locus_tag="NOB74_002354"
     CDS             2097..2930
                     /locus_tag="NOB74_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HCI1221498.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2946..3683
                     /locus_tag="NOB74_002355"
     CDS             2946..3683
                     /locus_tag="NOB74_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HCI1221499.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3838..4806)
                     /locus_tag="NOB74_002356"
     CDS             complement(3838..4806)
                     /locus_tag="NOB74_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HCI1221500.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5038..5871
                     /locus_tag="NOB74_002357"
     CDS             5038..5871
                     /locus_tag="NOB74_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HCI1221501.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5905..6744
                     /locus_tag="NOB74_002358"
     CDS             5905..6744
                     /locus_tag="NOB74_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1221502.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6770..7330
                     /locus_tag="NOB74_002359"
     CDS             6770..7330
                     /locus_tag="NOB74_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI1221503.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7529..9250
                     /locus_tag="NOB74_002360"
     CDS             7529..9250
                     /locus_tag="NOB74_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HCI1221504.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9415..10557
                     /locus_tag="NOB74_002361"
     CDS             9415..10557
                     /locus_tag="NOB74_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI1221505.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10573..11784
                     /gene="thiI"
                     /locus_tag="NOB74_002362"
     CDS             10573..11784
                     /gene="thiI"
                     /locus_tag="NOB74_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HCI1221506.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4133 a         2040 c         2523 g         3450 t
ORIGIN      
        1 ccaatcactt gggtttcttt ttcttttatt attatgatga atcaagcttt ctgtttttgt
       61 cacgtatgtt gtaatcttta cgaaagagta gagttggcta ctcataatca accatacttc
      121 ccatcatcgc taaatacgaa ataaatcagc attcctacac caatcaaagc acaagctgca
      181 ccaagaaaag ggatgacatt cccaaagtta tctgtattca taagtatgcc accacccaca
      241 aacaaaaagc cgccagcaat caggtttttc attttattca tctcctttct tacgttatag
      301 tatttccttc tttcaatgag tattttgaaa gctatcttat tgtatgatgt tcttctaggc
      361 ctcttcttta ttatacaggc cattttcgtt atctcataga aatattcctt tttatctgaa
      421 aactattgta taccgtatga catttttctt catgaagttg taagtatatt ctcattcaaa
      481 tgaaaatttc atcatagaag agattgtatt tctaaattct taagagtaaa atacgaagta
      541 taacttggat ttggaaggat gattggatga aagctattac gcctgatatg acaacaaaat
      601 ttaacaaaca gtttcaagca aatatcaaac agcaggcatt gcagcgggca gttgtgaaga
      661 acggaattac tgcttctgct gaaaatgttt cagcacatgt ggagaataca ccggtatttt
      721 ctatagattt ggctacgggg aaagtggcta atcaaatgca atcggggcgt tgctggatgt
      781 ttgctgcact gaacacattc cgtcataaga tgctgaatca attccattta aaagagtttg
      841 aattatcaca aaattacact tttttctggg ataaatatga aaaggcaaat tatttctatg
      901 aaaacatcat tgcaacagga aaagaggcaa tcgatagccg gaaagtagct ttcttactcg
      961 ctactcctca acaagatggc ggccaatggg atatgatcgt ttcattattc caaaaatatg
     1021 gcgttgtgcc taaatcggtg atgccggaaa gtgcgaatag ttcaaattct cgagatttga
     1081 ataactactt gaacaaatta ctgcgtaaag atgcagtagt gttacggaaa atggttgctc
     1141 aaggagaaac attagacgct attgaagaaa agaaagaaga aatgctagaa agcatttata
     1201 acttcttagc tatctcatta ggaacacctc caaaagaatt cgattttgag taccgcgatg
     1261 aagaaaagaa ctatcatctt gaccgaggac tgacaccaca aattttttat gataaataca
     1321 tcggtgtaaa attagatgat tatgttagcg tgatcaatgc accaacaaaa gacaaaccat
     1381 tcaatcgttc ttatacagta gagatgctag gaaatgtcgt tggcgggaaa gaagtcaaat
     1441 atctgaatgt tgatatggaa actttcaaaa aattagcgat tgctcagctt gaagaaggag
     1501 aatctgtttg gtttggttgt gatgtaggtc aatcttctac tagaactagt ggcatcatgg
     1561 ccttagatgc ttattcaatg gatgatctat ttgatacgga ttttacaatg actaaagctg
     1621 aacgtttaga ttttggagaa agtctgatga cccatgcgat ggtattgacc ggtgttgact
     1681 tagtagacgg gcaatcaaca aaatggaaag tcgaaaatag ctggggcgaa aaagttggaa
     1741 agaatggctt ctttgttatg agtgatgcct ggatggacga atatacgtac caaatcgttg
     1801 taagaaaaga tttattgacg aaagagcaat taaatgcgtt caatgaagaa ccaattgttc
     1861 tatctccgtg ggatccaatg ggtgctttag catagacgag tatttcaatg aagagtatgt
     1921 agtaaagata aaaagagctg gcttaagcca gctcttttta tctttaaagt ccattccctg
     1981 ttttttatgg tccctgtgct ataattctaa ataaaggata aggattggaa ataatccttt
     2041 tatcattaaa aatatgatga cgaagtagaa taaaattggg agtagggggg aaagtcatgg
     2101 atatccaaac tgttttatct gatctgaaat taaatggtaa agtgattcca gttgttggtg
     2161 gcgatgttaa tcagacctat cgtataaaaa ccgaacatcg tgcttatttt ttaaaaatcc
     2221 atccgaatgt aaaaaaagga ttttttgaag cagaagtaga cggattaaaa gaactgtcag
     2281 cattcgtacg tgtaccggat acgtatatgc taggtgaaac aagtgaaggc gcttatttgt
     2341 taatggaatg gatcgagccg ggaaaagggg atcaacgaga tcttgctgca gctttagcta
     2401 atctccatca gcaaacagcg ccacaatttg gttttcgtaa agataactat ttgggtacac
     2461 ttgttcagaa aaattctttt gaagaagatt ggtggacttt tttctttaaa gatcggcttg
     2521 aatcccagat ttctttggca gaagaaacga atcgatggaa tgtacagcgt caagaaaagt
     2581 atctgcgatt taaagaacgt gtattgaaat cggttgaacc aaaaaagatc actccacgcc
     2641 tcttgcacgg agacctgtgg agtggtaatg tgttctttga ccagcaaggg catccagttt
     2701 ttgtcgaccc agctgtttct tatgggaatc gggaacaaga tattgcaatg agccagttat
     2761 tcggtggttt ccgaccggaa tttttagatg cttatcaaac tatatttcca ttagaaaagg
     2821 gatggaaaga ccgactgccg atttaccagt tatattatct tttggcacat ttgaatatgt
     2881 ttggagaaag ttacggttcc caagtagatc aattactaga aaatttttaa gaggagggcg
     2941 tgtttttggc aaaaaaatat accaaaaagc atgaagtttc atattatgag tgtgacatca
     3001 accaaacgat gacatttcct tcgatgttag gagtagttat caaaacgtct gaagatcaaa
     3061 gcgaccagtt gggaagaggc agtgaattcg tcaatagctt tggacttact tgggtcatca
     3121 cgaattattc catggagatt aatcgtctcc ctagagtcgg tgaagtaatc tcagtaacga
     3181 ctcaagccat ggagtacaat aagtttttct gttatcggaa cttctggatc catgatgaag
     3241 atgggaaaga attagtcaaa atagaatctg ttttcgtatt gatggatttt gtgaatcgaa
     3301 aaatgagcag tgttaatgaa gagatcattg ctccttttga gagtgagaag atcaagaaaa
     3361 tcaagcgtca ggaaaaaatt gaaaagattg attcgggctt catgttgcca tatcgtgttc
     3421 gtttttatga tatcgatagt aatcagcatg ttaataatgc gatgtatttt aattggatca
     3481 ttgacgtatt aggatatgac tttttgacta cgcatgttcc agaaaaagta attattcgat
     3541 ttgataaaga agtagagtac gggaatgaga tcgaaagcca ttttgaacaa atccctatcg
     3601 aaaatggtgt caaaacaaaa catgaaatcc gaatgcaaga acagctgtat tgtgaagcaa
     3661 atattatatg gaaaaataaa taaaaaagag gttgtgacag aagggggcaa cttcaagaaa
     3721 taagaagaaa tttacgaaaa ttgtttctca aatttttgta aattttcgac ttagttttcg
     3781 aagaagctat ttttgtcaca gcctctcttt ttaagtttag ctattagata atgatgttta
     3841 gttttggata aacgaaatca attcttcacc cgacaaacca tagtttacag caatcaatag
     3901 ttttaaacgt gctttttgac tattaatact gttacagaaa ataatcccca ttttttctag
     3961 ttcttttccc ccgccttcat aatcataaac aggctctgcg attccattga aacaacgaga
     4021 aacaagtact acagggattt tttggacaag aagcttttcc aaagcagcta aggcttgtgg
     4081 agggagattc cccgcaccta aagcttcgat taccaaaccg tctactttcg tatgggcgat
     4141 ggcttccaat aagtcccctt gcatcccagc atatgcttta acgatcggga tagtcccatc
     4201 tacagcggaa atgtccagtc gctttgtttc taaaagttcc tgcaagaata aaattcgatt
     4261 cttagttact aagccgatgg gacccaatgt aggtgttcgg aaagtagcaa catttgtggt
     4321 atgggtcttt gtcacgtagc gtgcagaatg gatctcatcg ttcatgacca ccaaaacccc
     4381 cttatctagc gcttcttcac aacttgcgac acgaatcgca ctttcaaaat tataaaggcc
     4441 gtcacttcca agttcattac ttgaacgcat tgccccagtc aaaacaattg gtaatttgtt
     4501 gccaatcgtt gtatcaagaa aaaaagcagt ttcttctaat gtatctgtac cgtgtgtgat
     4561 caccactccg gatatacctg atgcataagc ggacaagata cgttctttta ataccaacat
     4621 gtgagaaggc atgatgtgtg gtgagggaag attgaagata tcttcaacta ataattctac
     4681 atgcttgggg attgtgattt ctgcatctaa taatgggttt gccacatcag gactaacacc
     4741 gcccgtgagc atgttttctt tcatggcgat cgttccgccg gtgtgtagta caagtatttt
     4801 tttcatttta cagacttcct tacgaataat tttgcatagc cgttaaatct tattgtatac
     4861 tatataaaag agttttgcta tcagtgaaga ataacgaata gcctaactta tcataaaaaa
     4921 gctgacctta ttaaaatgga aaagactcaa ccttgacctc ctaatacaat ggagtatctg
     4981 gttgagtttc ttttacaaga aagcagccaa ggaaatcaat cacgaaggtg gccggaaatg
     5041 atcagaatcg gattaacatc gtttaaagaa catgacaaat taactggtaa aaagaataac
     5101 actctttatg aatatgcagg gtttctaccc ttagtggaat tagatactgc ctattatgga
     5161 attccccgaa agtcctcagt tgagaattgg ataagtgaag tacctgaatc atttcgcttt
     5221 gtagtcaaag tctatcaagg aatcagcggt caaggagact ggaagcctta ttatcagacc
     5281 gaagaagaga tgattgcgca ttttttagat gttatgtcgc caatggtaga tgctggaaag
     5341 atgttttgct ttttagtcca attcccctca tcattcaaat gtacgaaaga aaatgtccag
     5401 tacttgcgca aacttagaaa gtggtttgag ggttatcctg tttctataga attgcgggat
     5461 tattcttggt acagcgatga atttcttgaa cgtacaagaa actttatgtc tagagccgct
     5521 ttttctttag ccatcatcga tgagccacag ttgctgaata caacgattcc ttttgatcca
     5581 tttgtcacca atccgaactt tgctcttttt cgattccatg gtaggaatgc gcaaggatgg
     5641 caagcaaatg ataaagagtg gcgtaaaaaa agaacgttat atcgttattc agaaaaagaa
     5701 ctgcaagaac tagcacatga agtcaaagta gttgattcta agacaaaaga ggtaggtgtg
     5761 atttttaata ataattctgg tggtgatgcg gctgaaaatg cattagcact gcaaaaaata
     5821 ttaaatatca agccagatgg actcaatcca acccaaatgg atctgtttta agggcttatt
     5881 ttattcaaga aaggggcgaa gtctatgatc aaagctattt tttttgatat tgacggaaca
     5941 ttggtcacca atcgttcaaa agcgttggaa tcaacaaaac aagcaattga atatgctcgg
     6001 aaaaacggca ttttatgcgg tgtagcaacg gggcgcagcc cagtaaagat caaagaaatc
     6061 attgatgaat tggaattaga tatgtatgtc gtgtataatg gtcaactggt ttttactgca
     6121 gatcgcacga ttatcgacca cccttttgaa caaaaagtat tggaacatat tgttgaattt
     6181 gcagatgaga accatcgaca aatcgttttt ggtgcgagaa atcggttaga tggatcaacg
     6241 acgatgctat taggacaatc gatttttatc aagcgactag tcagcttttt accgcgtaaa
     6301 ttcccggtac gtctgatgaa aaaaatcctc caggttttta gccctcaccg acaaaaggat
     6361 cgttatgaaa cgttagagat attaaaagaa ccaatttatc aatgtatatt gctcagtccg
     6421 gagtcagaac agaaaaagtt agaacatcgc tttcccgagt gtacgtttca gcgttcaaat
     6481 acgtatactg tagatatcat cccaaaaggt ggttcaaaat tactaggcat ccaagctttc
     6541 gcaaatgctg tcgaaattga aatggaagaa attatggcat tcggcgatca ttacaatgat
     6601 atcgagatgc tgaaaggtgt aggaattgga gtggccatgg ggaatgctca gatcgaagta
     6661 aaacatgctg cagactttgt gactcaatca aatgaagaag atgggatata cgaaggactg
     6721 aaacacttcg gtctgattta ttagtcaatg aaagaaggaa aaaatcagta tggaagcaga
     6781 gacacctttt caaaaagtag aaacattcca caaaactttt gatccaagaa gaccagagat
     6841 acccacggct tttacagaaa atgaagctca tacacgtgct gcgttcaaaa tagaagaact
     6901 tgttgaattt gttgcagcta cttcacctaa taaagaacaa ctgcatgaag ctgttatgct
     6961 gctgcacgaa gcattagata aagcagaaga aaaaatactt ggtaaaacac agtggggaag
     7021 tgatccgctg gttgaacaag tagatgcact gacagatatc ctttacttta cttatggttc
     7081 tttttcatta ctaggaatag tgcctgatcg aatattcgaa atcgtccatc aggcaaatat
     7141 ggggaaatta tttccagatg gaaaacctca ttatgaccct gtaacaaata aagtgttgaa
     7201 acctgaaaac tggcagatgg aatatgctcc agaacctaaa atcgcggcag aaatccaacg
     7261 tcagattcaa gaagcgattg ctaagaagaa atccgctgat ataggcatgt gcacaaatga
     7321 aaaagagtga tcagagtttc actatttttg ttatctttat acgatggaaa aacaaaagat
     7381 tttcgtttaa gttagtgaat gcatgaaaat agtatgctat aatctagaat agatgtcttt
     7441 tgcacgagag acgtattatt tggatttatg ccaagcagaa cgccatctgt tgcataaaag
     7501 atgcatactg aaaacggagg aaccataaat gggaaataat gttatcatcg gaatcgtcat
     7561 tgcaatcatt atagtcgcca ttgtcgtctt tttggttagt tacttgatga agaaaaaaaa
     7621 ccaagatcga ttggatgcct tagaaaaacg caaggaagaa ttatttgact tgccagtgat
     7681 tgaagaagtc gatgatgtta aaaaaatgca tctggttggg caaagccaaa atacctttcg
     7741 tgaatggagt caaaaatgga atgacatatc tacttcctcg ttcgctgaac tagaaagtca
     7801 aattttcgaa gtggaaaacc tcaatgaaag ttttcggttc ttaaaaggaa aaaaagcagt
     7861 tgttgaagca gaagctacaa tggaccaaat ggagaaacaa gtgacggaaa tccgtgaagg
     7921 tctaaaggaa ttgcgggaaa cggaagaacg caactcacta gctgttcagc aggcacttga
     7981 cgtctatgaa gaactgaaag aaaaagtcag agaagacgag catgaatacg gaccagctct
     8041 ttttgaattg caaaaacaga tcaaagtgat cgaaaaagaa tttacgcagt ttgtgacttt
     8101 aaacacttct ggagaccctg ttgaagcccg cgaggttttg gataaagcag aaaaacatac
     8161 gtatgaagtg gaagctctga tgaaaaaaat tccaccgctg tatgaggagc tccataccac
     8221 tttccctgaa caacttgaag aaatcagtga tacttacgag aaattgatgg aagaacaata
     8281 tgtattccca gaagaagatc ttgctgaaga tatcgcaaaa gtaagtcgaa gaattgaaaa
     8341 ttcattagcc aatcttgaaa aaacagaagt tgaaacggtc gaatttgaaa accgtgaaac
     8401 agctgatttg attgattcgt tatatgatat cttagaacgg gaaatggaag ctcagagata
     8461 tgtaaaaact aaccaatcaa cgattgcaga gtatatcaaa catacaacaa agaataaccg
     8521 tcaattattg attgagctgg atcacacatc tcaaagctat acattgaacc acaatgaaat
     8581 tggccgtgta cgaggtttcc aaaccgaagt ggaagaaatg gaacgtcaaa atgaacagat
     8641 gattccacag atccgtcaac acgaaattcc ttattcagaa gtgcgcacgt tctataaaac
     8701 agtcttcaaa gtcttagaag atatcgaaaa gcaacaagta gagatcgacg actcattaca
     8761 tgaattgaga aaaggcgaaa aagaagcgca agaaaagatc gatacattcg aattcaaatt
     8821 gcgcagtttg aaacgttttg tagaaaaaca acgtttgcct ggcttgccga atgattacct
     8881 agaattcttt tttgttgcta ctgaccgtat tgaagaacta agtgttgtct tgaataaaat
     8941 tcgagtaaac atggaagagg tcaatcgttt agttgctcta tgtgaagaag atctagaatt
     9001 attagataag aagacacatg atttagtaga tgcagcagca ttaacggagc aaatgctcca
     9061 atatgcaaat cgttatcgtc atacacacga agaagtgaga gaagcaattg ataaaagcta
     9121 ctatttattc aataaagaat atcactatca agaagcatta gacgaaatcg gtacagcatt
     9181 agagcgagta gaacctggtg ctttcaaacg catcgaagat ttttatttta atcatccaga
     9241 cttagtataa agcaaaaaag ttagtaaacc agcaagagca agacggatta ttgtcttgtt
     9301 cttgtctttt tttgtatatt tgaaaattga aacaagtgaa aatttcacct gctcttgaaa
     9361 gcaccttgga caaccgttat aatagaaaag aatttcaaaa aagaggggtt tcttatgata
     9421 tattttgata acagtgcaac aaccccaatc tttccgcaaa gcttagatgc atatgtaaaa
     9481 accagtcagc ggattattgg gaatccatca agcttgcatg atttaggcaa tcaagctaac
     9541 cggttgttgc agcaagcaag aaagcagatc gctgatttga tccatgtaga accagaagaa
     9601 atctatttta cttcaggcgg aacagaagga gataactggg tattaaaagg aacgatgatc
     9661 gaaaaaagag aatatgggaa tcatatgatc atttcaggag tcgaacatcc ggccgtcagc
     9721 gagacagcag aacaattaaa agaattagga atcgaagtaa gtatcgcccc agtggataaa
     9781 cgcggatttg tacgtgtcga cgaattgaaa gaattaataa gaaaagagac agtattagtc
     9841 tctgttatgg ctgtgaataa tgaagtagga tcgattcagc ccatccagga aatcagtgat
     9901 cttttggatg attttcctaa aattcatttc catgtagatg ctgttcaggc gattggaaaa
     9961 gtaccattct cgcaatggtt gacagaaaga gttgattttg caacattttc agctcataaa
    10021 ttccatggcc cacggggaac tggtttcatt tattggaaaa agggtcgtcg tttagcacca
    10081 ttactgacag gtggagggca agaaagaaat cagcgaagtg ggacagaaaa tgttccaggt
    10141 attgtggcta tggttaaagc tttacgttta tcattagaga taaaggaaca aaaacctgag
    10201 cagacacaac gcttaaaagt agctctaatc aatgcgttga agacgtatga gaaagtgacg
    10261 attttttcag aaggaactga ctatgcaccg catattttat gttttgctct aaaaggaatt
    10321 cgcggcgaag ttctcgtcca tgccttagaa gaaaaacaaa tatttgtttc tactactagt
    10381 gcctgctcct cacgtaaaca tatggcaagc agtacattgc acgcaatgca tgtaccaaat
    10441 gatctggcta catctgctgt tcgaatcagc ttagatgaaa acaattcgct tgcagaagtc
    10501 gagcaattta tgattatttt caagcagctt tataagaaat tttctgcaat caattaaaag
    10561 aggagtgttc ttgtgaaata cagtgaaatt atggtccgtt atggggaact ttcgacaaaa
    10621 ggaaagaatc gaaaaagctt tatcatgcaa ctagcacaaa atgtcagaca agctttgaaa
    10681 gactttccag aaatcaaaat ccatgctgat cgggaccgga tgcatctttt attgaatggc
    10741 gcagacgggc agctagttat tccaaaacta gcaaaaatat ttgggatcca aaatttctct
    10801 ccaagtattc gtgtagaaaa agatgtcgaa gttttgaaac aagctgttca agacatcatg
    10861 aaagaaattt atactgggaa agaaacattt aaaattatcg ctaaaagaag cgatcaccaa
    10921 tttgaattga caagtaatga attgaatcaa acattaggta atgctgtttt tgatattttc
    10981 ccgcatatcc aagttcaaat gcgtcaacca gatattccat tacgtgtaga gattcggcgt
    11041 gatggcgctt atctatcgta tgaaacgatc aagggagctg gaggattgcc cgtaggaaca
    11101 agcggaaaag gaatgcttat gctttctggg gggattgatt ctcctgtagc agggtacttt
    11161 gccatgaagc ggggagtgga aattgaagct gttcattttg ctagtccgcc gtatacaagt
    11221 gaacaagcac tgcaaaaagc aaaagatcta acagccaaac tagcacctta tgtgggaacg
    11281 atccatttta tcgaagtgcc atttaccgag attcaagaag aaatcaaaaa gtcagtgcca
    11341 caaggatatt ggatgacaat tactcgtcga atgatgttgc gtttgaccga tgaaattcgc
    11401 cgtattcgtc atggtttagt cattttgaat ggtgaatcat taggtcaagt ggcttcacaa
    11461 actttgcaaa gtatggtggc tatcaatgaa gtaacgaata cgccaatcat tcggcctgta
    11521 gcgacaatgg ataaacttga aatcattgaa gtagcagaac agatcgatac atttaatctt
    11581 tctatccagc cttttgaaga ttgctgtacg atttttgctc ctccacagcc aaaaacacgc
    11641 cctcaactgg aaaaggtcca tcaatatgaa gagcgtttag caatagatga aatgatccaa
    11701 cgagcactag ctggcttgaa gatggaagag atacaagcag aatcgtctaa tgaaaaaact
    11761 gaagaatttt cagaattgct ataagaggtt atgaaaatag tgttttgacc agagtattag
    11821 agaaacaaaa cgaaaaaata gctccatgta ttttaccgtt tttgaactaa tgtcgaagat
    11881 tagctgattg aataccattt atcaagaagt tatggaaaag ccggttcttt tttactaact
    11941 gaaaaataaa attttattta gagatcaagc tacagttgat aaatgatata aaaaagagaa
    12001 tttcccatga aatagcgagg ttgtgacaga agtgggcagc ttcaagaaat aagaaggaat
    12061 ttacgaaaat tgcttttcaa atttttgtga aatttcggct tatttttcga agaagttact
    12121 tctggaacac cgtgtatcag aggttg
//
LOCUS       DAIGWC010000081        11773 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.082, whole genome shotgun sequence.
ACCESSION   DAIGWC010000081 DAIGWC010000000
VERSION     DAIGWC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.082"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            514..1077
                     /locus_tag="NOB74_002363"
     CDS             514..1077
                     /locus_tag="NOB74_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221507.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1138..1503)
                     /locus_tag="NOB74_002364"
     CDS             complement(1138..1503)
                     /locus_tag="NOB74_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221508.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1579..1824)
                     /locus_tag="NOB74_002365"
     CDS             complement(1579..1824)
                     /locus_tag="NOB74_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1221509.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1894..2148)
                     /locus_tag="NOB74_002366"
     CDS             complement(1894..2148)
                     /locus_tag="NOB74_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221510.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2312..2635)
                     /locus_tag="NOB74_002367"
     CDS             complement(2312..2635)
                     /locus_tag="NOB74_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221511.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2822..2895
                     /locus_tag="NOB74_002368"
     tRNA            2822..2895
                     /locus_tag="NOB74_002368"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2856..2858,aa:Ile,seq:cat)
     gene            complement(3280..3777)
                     /locus_tag="NOB74_002369"
     CDS             complement(3280..3777)
                     /locus_tag="NOB74_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI1221512.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3817..4626)
                     /locus_tag="NOB74_002370"
     CDS             complement(3817..4626)
                     /locus_tag="NOB74_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1221513.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4960..5817
                     /locus_tag="NOB74_002371"
     CDS             4960..5817
                     /locus_tag="NOB74_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCI1221514.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5810..6712
                     /locus_tag="NOB74_002372"
     CDS             5810..6712
                     /locus_tag="NOB74_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCI1221515.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6745..7095
                     /locus_tag="NOB74_002373"
     CDS             6745..7095
                     /locus_tag="NOB74_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI1221516.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7144..8067
                     /locus_tag="NOB74_002374"
     CDS             7144..8067
                     /locus_tag="NOB74_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI1221517.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8145..9038
                     /locus_tag="NOB74_002375"
     CDS             8145..9038
                     /locus_tag="NOB74_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1221518.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9076..9639
                     /gene="amaP"
                     /locus_tag="NOB74_002376"
     CDS             9076..9639
                     /gene="amaP"
                     /locus_tag="NOB74_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCI1221519.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9653..9841
                     /locus_tag="NOB74_002377"
     CDS             9653..9841
                     /locus_tag="NOB74_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCI1221520.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9854..10756
                     /locus_tag="NOB74_002378"
     CDS             9854..10756
                     /locus_tag="NOB74_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI1221521.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10788..11030
                     /locus_tag="NOB74_002379"
     CDS             10788..11030
                     /locus_tag="NOB74_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI1221522.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(11286..11657)
                     /locus_tag="NOB74_002380"
     CDS             complement(11286..11657)
                     /locus_tag="NOB74_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221523.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4173 a         1984 c         2232 g         3384 t
ORIGIN      
        1 aaaaattcat tggtcgttga atgggctgaa tagtagtgta taaaacaatt ttgtggagcg
       61 tgaagctttt atggtagagg aaaatacgaa taaagtgatg ttgataaaaa gattcctatc
      121 ttgaatatga atcgagatgt cttgaaaatg aatgagtttg accaatcatt atcctatcga
      181 aatttacagt ttcgttcgat tggtctgtca attaatgaaa aagtaaaaaa gaatatgttc
      241 taggaagagg gcggcacatc taaattttta agtaacggac agttcaaata tcaagcattg
      301 aaagaggcta tcctactgtt tgaaggaata cgaatatata aaaacgacaa agaggaaaaa
      361 gtagttcatt aaatcccttc aagtgatgaa agaatgagat ctaataaaac ctgatctttc
      421 atctgttttt ttaataacgt aataattttt ttattttttg tgctttcgcc gttattgtag
      481 agtgatttag cattcttatt tttaaaaata actgtgttat atattaaaaa aggcataata
      541 gttataagct tttttaaaga atatttagaa attattaatt ttcgtctgaa aacaaaaaaa
      601 gaaagcgtta ttattttagt ctattttcag ggggggaacc ttatgataaa aaaactattt
      661 ttactatcaa tattaacgct agcaatggca ggttgttctg actctggctt agcaactgaa
      721 ctgatcacaa aatcaactga agccacgaca gaggagttaa aatgtggaaa cgatcacagt
      781 gactacagag gcttaaatcg acgatgcatg ggaatattag gcagaagcaa ttgtaagcat
      841 cgatgtagta atcgaagaag gtgtagaaga agcaacagaa aaatcaaaag aaagatcaaa
      901 agaagcaatc tgtgctgtgc atcgtataca gacgtcgaag atgcggtact tttaaaccac
      961 gtcaggagat gttcatttat gtctagggaa gttggcgatg aaccaaaact agagtacgct
     1021 tttagttttg cacgtgagga tgaagataac cctaaaactt acgacatttt agcttgatct
     1081 aagatggtta aagcttttta atgaagtaag aggagataga aggcttttct agttatatta
     1141 ggtaagataa attccttttt gctccaaatt tgctaaacat tctgctagat aaacttcatc
     1201 gtgttccgga taaatcggca cgttgcgctc tacagtaggt aaatcaaaaa atgcttcgca
     1261 tgatttgcca cgatacatag gatttttcca ctctggtgct gggctgtaac cacgtttttc
     1321 catttcatcc atgacaagct gatgatattg gaataatcta taaggagaat agtgaaaaac
     1381 ataatccaca gtagcatgtt tctttcccca gccatttcct cttaatgcac agcattcccg
     1441 atgttgtcct aaaagctgtt gacgaggaag ctttgaaatc aatttttcat gccataatcg
     1501 catagaaatg tctcctttat atatagattg ttaaccttag acgttaaatg aaaaaaccag
     1561 caccaaggct ggaaaaaatc acttcagttt gcttgctgtt tctgagcgac caattaggta
     1621 atcaacggaa atatcgtaaa agtcagcgat atagattaat tcaatgatgc ttggaatttc
     1681 ttctccttct tcgtacttac gatatttgaa taaaggaata cttaacgcgc tagaaacagc
     1741 tacttgagat aaagatcggc cagttcttaa gaaattcaga cgacaacgta aagtatccag
     1801 taaaatagct tcttcgatac tcatttaatc acctttcatt atagtagaat agttataatg
     1861 actatagaaa gctacacatg caatcaatag tactcaatgt tttttattta aacgtatcaa
     1921 ataaagaatg acgatcaata aagacaaaac cagtcctgat aattcttcta taaaaacact
     1981 atcgggttca aagtagttgt aattaaaaac tttccacata aagtagatag ccggaagagt
     2041 caaaatagct aaataaaacc gttctttgtt ccaattcata agataaacaa tacttgcgac
     2101 cagtgcgacc gcaggcaccc aaaacaaaac tctcaccaac gtaatcatgt aacggactcc
     2161 tcaacgattc atataataaa agataacatg ttattgcata catcacaaat gaaatgctag
     2221 gaaaataaaa gaagaataga tcaatgaaaa atgaaaaagc agaacagttt tctgctgata
     2281 agcaggaact gttccgctga atgtgtctta tctatcgaga aaaaatcaat ggattgatat
     2341 ctaagtaatt caatacatat aaaaagagga cgatcgcatt cactaaaaag gaaagaatga
     2401 tgatcccata gcgaatggaa acatatttaa caaatacttt tgtttgaata cgggcatatc
     2461 tttttccttt atagctgagc atcatgacaa gaagcaaaag ggtaatcaca ccttgaaaaa
     2521 tcattccaat aaacagaatt cctgaggttt gataatttaa ttggagaaaa taagctgctg
     2581 ccgcaactaa atcgaataaa atcgcaataa atggcaaaat aatcactcct aacattgaga
     2641 ataaataaaa gaataacatt ttttctaaaa taagcaaata aaaattaaag taacaaaata
     2701 gttatgacac aagtaaaaga aataagaata acaatattat tttacttata ttttgaaact
     2761 tgtgagagtt tgtcattcgt gctatagttg aaaagtaaca aaaataaatt ttatttatga
     2821 tgtaccttta gctcagttgg ttagagcaga cggctcataa ccgtccggtc gtaggttcga
     2881 gtcctacaag gtacataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     2941 ccaagtaaaa acagcttctt atgtttttac ttggctgttc ttattactgc agatgcaagc
     3001 ttttgaatac cgtttaagga agaggttgtg aaatcagcgt tttgacctga gtattagctt
     3061 aacaaacgga aaaatagttc ctcatatttt gccgtttgtt aagctaatac cgagggtcag
     3121 ctgattgaac accatttaag aaagaggtcg tgagcctgcc gtttcactct gtgtcataaa
     3181 aaagccaatc tactttgata gaaaaagcac gtaggactaa aacagttctg cgtgcttttt
     3241 ttattgtgtg ttaaatatcg taaatgaaga tagatatttt tatgattcga cgatagagac
     3301 gttgaaatct ttcaacagct ctaaagcgga ttctccgtgt tttctactgg agactaacat
     3361 tggatcaaca aaaaagtctg cttcaggaaa agcactctgc aggcctatca gattagagag
     3421 tacacacaag tttgtttcaa tcccgactac ttcgatctct ttttgttctt ctttgctttc
     3481 aaataaagtt tcctggattt cagctaaagt ttcaggtgga atcgtaaagt aatacttttt
     3541 aatcactcgt tcattttctt gtggagaaag aagagggatc aattgcaaat cttctcgttc
     3601 ttcttctttg tccttcagtt caactggtat atcccgtgtg aagagaatat attcattatt
     3661 ttggcgtgct ttagctaatc tttgagcaat acgttctgcc aattgatctg actctggaat
     3721 ataaaattcg ctgtttggat caagaatatg attttgcata tcaataataa ctaacatttt
     3781 ctttcctcct acattcatat cgtcatttta ttctttttaa tagaagtttt ttaaaatata
     3841 agcaacacca gcttcttcat tcgtcagtgt tacttggttt gcaatttctt ttacttgtcg
     3901 ctgtgcattc cccatcgcaa tactcaaccc gctgtaattc aacatagcaa tgtcgttttc
     3961 ttgatcgcca aaagccatga tgtcactcga ttcgattcca aggtaatccg ccagaaaaac
     4021 aagtgaatga gctttagtga tacctgtagg cgtgatttct aagaaatgcg gatcagagaa
     4081 tactgattgg ataccatctg cttgcagatc tctttgtagc ttctgtagtt tttcttcact
     4141 cttatctgtt aatgctaatt taagatagct aagagaagga tcttccaaca tatttaaaat
     4201 ttgatcaaaa gaatggttct gtaaattgaa atgttcataa taagggtcat ctttgactag
     4261 atttgattca tcgaatgtca gctgatcatc ttgggtttct cggctagcaa tgatggatat
     4321 tttcgcttct tgagcataga agaaggcttt tctcagtgta tcgctatcta tttttgaacg
     4381 tctgagaact ttcgccattt ttccatcctt catttcagca atcagtgaac cattggaaga
     4441 aatcaaatag ccaccgattc ctaattcgga aaaaatatct ttagcagaaa tgctgttcct
     4501 tccggtagcg acggttacga ttccgccatt ttcatcaaat ttccgaagtg cttggatatt
     4561 ttcttctggt atctttccat ttcgatcaag caaggtaccg tctaaatcaa tcgctgctag
     4621 tttcatttta tcttcctact ttctttttac atatctattt tcctgttacc ttaagattaa
     4681 atgagaattt aaaaaaatga aactaacttg ctttgtcatt atgaattttt tcaaaaaaca
     4741 ttcttaagaa aaaggtggct atatatagta gtttttggtc aatacctttg aataaaaagc
     4801 catgaaaaac gaatagttag cgcttaccga tgcgttttgt gataaaaaaa ttttaaaata
     4861 ttcaatgaaa acaaagcata tattttgctt taaaaccaaa tgaggaatat tctagatgta
     4921 gaacaggtta gaaaaagatt agaaaaagga gtgattttga tggagaagag atacggcgta
     4981 gttcctgtgg taactgcttc agacgaaaat tatgctcctt acttgagcgt gatgatcgca
     5041 actgcattag aaaattgcaa taaaacaaga cgcataaaat tttatgtgat tgacgatggt
     5101 ctatcagaat atagtaaaga aggattggaa gaaacggtaa ataaatattc aagtaatgca
     5161 agtatccaat tcctgacagt ggaaaaagat atctacgaag acttcctagt cagtgaccat
     5221 atcacaacta ccgcttactt aagaatttct ttaccaaact tattagctaa agaggattat
     5281 aagaaagtcc tttacttaga ttcagatgtg ttagtactag acgatatcgt aaaactatat
     5341 gatgagccgt taaatggaaa aacaatcggc gctattatcg atccaggcca agtgaaagct
     5401 ttggaaagat taggaatcga ttccgatgac ttgtacttca attcaggagt gatggtgatt
     5461 gacattgatc aatggaataa aaaagaaatt acagaaaaaa ctatccatta cctcagtgaa
     5521 aatggcgatc gaatcatcta tcacgaccaa gatgctttga atgctgtact ttatgaagat
     5581 tgggaacaac ttcatccaaa atggaacatg cagacttcgc tgatttttga acgtcatcca
     5641 gcaccaaatg aaaaatatga acgtcagtat aaagaaggaa atgaaaaacc ttcgatcgtt
     5701 cactttacag gacatgataa accttggaat acgttgaaag atcatccgta taccaattta
     5761 tacttaaaaa aattagcaca cagtactcta acgaaagtag gcgagatcaa tgaataaaaa
     5821 agaaatagca gtagtcgcaa gttgtaacac aaaattcgta ccacatttag ctgcattatt
     5881 tgtctcagta ttagataatt gcaacccgtc taaatttgtt cggttctatg tgattgacga
     5941 tgatatcgat tttgaaagta aacagctttt acgcttctca gtgaaaaacg cacgaatgaa
     6001 ctcagatgtg gaattcttga aaatcaataa agaattcttt acaaatgtgg taatcagcga
     6061 tcgtattcca gaaacagctt attatcgtat tgcgattccg gaattgttcc gcggcacaga
     6121 agttgaacgt atcttatata tggattgcga catgatcgct ttacaagata tctctaaatt
     6181 atggcgtctt gacttcggtg attcaatcgt agcagctgtt gaagacgctg ggttccatca
     6241 acgactggaa aaaatgaaaa tttcagctaa atcaatgcgt tatttcaact caggtttgat
     6301 gctgatcaat gtgaaaaaat ggttagatga aaatattacg caaaaagtat tagatttcat
     6361 cgaacataat ccagaaaaat tacgattcca tgaccaagat gcattaaatg ctatcttaca
     6421 tgaccgttgg ttaccacttc atccgcgttg gaatgcacaa ggctatatca tggcaaaagc
     6481 aaaaaaacat ccaacagcag caggtgaacg tgaatacgaa gaaactcgca acaatcctta
     6541 cattatccat ttttcaggac atgtgaaacc gtggagcaag gattttgaag ggccaacgaa
     6601 gaaatattac gaaaaatatg cagggatgac ggctttccgt tgtgtagcta aattccctaa
     6661 atatccaaaa tatgcaaaag ttcaaccaaa aacagatgta gttgttaaat aatagaagac
     6721 aacaactgaa gagggggagt aggaatggaa attacaatgt ctaaaaatgc agtagagacg
     6781 ttaattgaaa aggttgggga aaatacaaaa atcgcactcg cgcttatcaa tgattccgat
     6841 ccatttctaa gggacaaagg tgcttttgca aaaggcagct tttttcaaat cattcctttt
     6901 gtttcggaat ttggagaata tgcgactaaa atcgagcatc cattattgga catctataca
     6961 tctaaattag agcaaaatta tttcggtaaa cgattgaaca tggacttcaa caaacagctt
     7021 gacagctttt cattagaaaa tgaaatcgca gtactcgatt ataatatcaa attaaagaac
     7081 tgcttcttca gctaatagtt tcgagaaagt ccaaaaagga ggtatacatt gagatactac
     7141 tttgtggatg aagaaaagaa tgtaatagaa acagatgaaa aaaaatataa ttggctcgta
     7201 cttgatagtg caaagcccga agagattgag caagcaatcg aagaattcga gcttcctgat
     7261 gatattttcg taggaaccga atatccggaa gaagtttctc ggatggagcg cctttatgag
     7321 acgaaactag agcatccatt ttctttggta gtgattaatc tagatcagtc agataatcgt
     7381 atcgaaaaaa aattaacgcc aatatctttt gtactttccg ataatctctt gattacttgt
     7441 atcgatagaa aaaccgaatt tgtggatcgg ctgctgacaa agcatggaaa tcatttaaac
     7501 tcgtttgaaa agatcatcac gtatacatta ttagatattt acacccatta cgtgaaagaa
     7561 ctaagagaga tgaaaaagcg aattgacgct ttggataaag cagctcgtaa aacaacggaa
     7621 aatgaagaac tgtataaaca ggcagatctt gaaagagaca tcgtatatat cgatcatacc
     7681 ttaagagatc aacgggaaac aatggatcaa ttatggaatt ctgaaacttt catcaaacgt
     7741 ttagacgatg aacagctact ctatgatgtc catttgagac agcgacaaac agaaaaaatg
     7801 atcgagatct atcgagattt attagagagt attggtgatc tattcaacgg gatgatggac
     7861 aataatctaa atcatatcat gaaatatcta gattcagctg cattaatcat ttccgttccg
     7921 gcgttgttcg cagggatttg gggaatgaat acaggaggat taccgggtaa aagttctgct
     7981 ctaggcttta tactcgtagt ctttggctct ttgatagcag cagtagtttt aggttaccat
     8041 ttataccgga aagattatac aaattaaaga atctatttaa aacaggtatc aaacaaagaa
     8101 atttgttttg gcaatacaat ttaaaaacta ggaggaatac agcaatgaca gaaccaaaat
     8161 taatcgaccc gcgaaacttg taccatacgg agaaatttcc taaacaagat caggatacac
     8221 cagctttaca gcagaatatg attcctgttc ctgattgtgg agaagaatcc tatgaaggca
     8281 ataatcaact agaaaaccgc cgtgtactaa tcactggtgg agattcaggg atcggtcgtg
     8341 cagcagcgat tgcatttgct agagaagggg cagatatcgc tcttcaattc ttcccaggag
     8401 aagaaaaaga tgcagaggaa gtagcaaaat acgtgaaaga tgcaggacgt aagattgtct
     8461 tactaccttt tgatcttcgt gacgaacaag cacctaaaga aatcatagat aaagccgtga
     8521 gtgaacttgg cgggctagat acgatggtac taaacgcagg acagcaaatt tcttgtcagt
     8581 ctattgctga gttaccactt gagcaagtca aagacacatt tatgataaac atcatcgcta
     8641 tgtttgcttt agtgaaagaa gctgttccgc atatcccagc aggaggagca atcgtaacaa
     8701 caacttctgt tcaagcattc aatccaagcg aacatttatt agattacgca gcaacaaaag
     8761 cttcaatcgc taactttacg atcggtttag caaaacagct tgcacctaaa ggaatccgtg
     8821 taaatggtgt agcacctggt ccaatctgga caccattaca actagacgaa ggacaacctt
     8881 ctgattcgat ccctgaattt ggtcagcaaa gtttactaga acgtgcaggt cagccaggag
     8941 aattagcacc agtttatgtt ttcttagcat cgaataaagc aagttatgtt acagcccaaa
     9001 tttacggagt aactggtgga gaagcgatca acttataaga agttgatcgt ttcaccccta
     9061 tgaggaggtg cgaaaatgaa taaaggtgta aaaacgatcg gagtgatcgg aacattactt
     9121 ttgctatctg tgcttttgtt tgcgatacta ttaagtgcaa cctatccatt gccttttcag
     9181 ctagagaagt ttcgattctt ttccatcact aattcatacg tgcaacaata tgtattttgg
     9241 cttgccgttg catttgctat tttgacaatt atcacgttac ttgttttcct gttttatcca
     9301 aaaacaatcg gaaactttct actgaaacat ggtgatgggg agttgacgtt ggataaaaaa
     9361 gcaattgaag gaatggttcg ttctcacttg catgaagatg aattcatcca ttcaccaaaa
     9421 gtaaatgtca aagcaacgaa aaacaagatc gccgtcaatg taaaagggga gttgaaacga
     9481 acttcagcac tcattggtaa aacaggaaca ttgatgaaag aaatcgaaaa tgaagtacaa
     9541 cacatattgg gaacaaaaga gccagtgaaa gtatcggtga aatacacagg ctttgaagaa
     9601 ccagctaaac gaagcaatga ccgcaaacga gtagaatagg gggggaccaa aaatgaaaga
     9661 actattttcg acatacaagc tccctatcat ctttggggta cttggattga tattagccgt
     9721 tttatggatc accgtgggct ttttcaagac cttattgatc ttgatcatgg cagcgatcgg
     9781 cgtcgctatc ggtttttatc tgaaacaaac gaaaatctta gatcactatt ttaaatctta
     9841 ggaggaaaca tccatgaata acaataacaa aaataataac aataaaatga acaaccaaaa
     9901 accagtgtct gcacatccag acccaacgac accaaaccaa tcaaatggtg tgaacgatga
     9961 aaagaacaaa acagcaccag tatctgcaca tccagatcca gtagtcccta acgttcaaca
    10021 aggagtagaa gagaagaaac atgatgcaga aaagcatgca cctcatcatc caggaactcc
    10081 agaatctaaa gttccagaac aacatgatgc aatcgatcct tctaaacctg tggaagagca
    10141 aaaacatcct tctgaccatg cgaaagcaca agaaaaactt agttctgacc acacaaacgg
    10201 acaaggaaaa cttggttctg atcatacaaa taaccaagga aagcatgatt ctgaacagga
    10261 agattcaatg cgcggtgagc tgaattatga agataaagtt gtgcaaaaaa tcatcggaat
    10321 cgcaattgaa caagtagacg gtttattatc tgcaaacggt ggtttcttct ctaatgtggc
    10381 aggaaaactt gtgaatacag ataatgtaac ggctgggatc gaaacagaag tcggtaaaaa
    10441 acaagtagca gttgatatgg atgtcattgt ggaatatggc aaagatatcg aaaaaatctt
    10501 tgaagaaatg caagaagtaa tcggcaaaga agtaaaaaat atgacacatt tagaagtgat
    10561 cgaagtcaac gctaacgtag tggacatcaa aacaaaagaa gaatttgaaa aagatcaaga
    10621 aacggtgcaa gacaaagtaa ctgacgcagc gaaaaaaacc ggtgaatttg cttcgaatca
    10681 aacagataaa gtaaaatcag cagctggaag cggcgcacaa aaagtaaaag aaaatacaga
    10741 accacgggtt cagtaataag gaagtaaaac attaggagga acgaaacatg ggatttattt
    10801 ggtcacttat cgtcggagga attatcggag caattgcagg agcaatcacg aataaaggtt
    10861 cttcgatggg gattattgca aatgtcgtag caggtttagt tggatcagca cttggtcaag
    10921 cattattagg ttcttgggga ccaagtattg caggaatggc aatcgtgcca tcattgattg
    10981 gtgccatcat tttagtacta atcgtatcat tctttgctcg aaaactgtaa aaagactttt
    11041 aaaaagaggt cgtgaaaaag ctgttcttca tcaagtaata agaacagcca aacaaaaata
    11101 gcttctcata tttttcattt ggttgggcat attatcgaag atgcaagctt ttgaacactg
    11161 tttatacgga ataagaggct gtgacaagac ttttgtcaca gcctcttatt tatgcgggca
    11221 aattcccaat tagattttta aaagtttttc cttaaatgtg tctttattga tacagagaag
    11281 cttctttaat aaaacaatgc ctccctaaat tttcttgaga taggaaaggt gaacatacaa
    11341 aataatacga ccactttgaa aacccagatg atccacaaat ggatcgtatg atactgatga
    11401 agtaaaaagc aatggatcag aaactcaaag agattgaaaa agacaaggaa gaaataatat
    11461 ctctttttta ctcttgtctg ttttagccaa taatagctcg taaagtaatc tagacaaaca
    11521 aatagaagta aacaaagttt cgtaagagca gcaatcgtat catgttgctc tgctagacga
    11581 ttgacgagca ggaaaaatgt tggtaatgga atatagatca cgagtaatga aagaaaaaag
    11641 taaacaataa atggcatact attcctccta attgtgtgag ttcgccctca ttttaaaata
    11701 acgatatttg tttgtgaagc tttttcgtgt cgtaacaaat gttatctaat gtatttttaa
    11761 ataaataatc att
//
LOCUS       DAIGWC010000082        11706 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.083, whole genome shotgun sequence.
ACCESSION   DAIGWC010000082 DAIGWC010000000
VERSION     DAIGWC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.083"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(40..1005)
                     /gene="nrdF"
                     /locus_tag="NOB74_002381"
     CDS             complement(40..1005)
                     /gene="nrdF"
                     /locus_tag="NOB74_002381"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HCI1221524.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(1055..3214)
                     /gene="nrdE"
                     /locus_tag="NOB74_002382"
     CDS             complement(1055..3214)
                     /gene="nrdE"
                     /locus_tag="NOB74_002382"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HCI1221525.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITTEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            complement(3373..3597)
                     /gene="nrdH"
                     /locus_tag="NOB74_002383"
     CDS             complement(3373..3597)
                     /gene="nrdH"
                     /locus_tag="NOB74_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HCI1221526.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            3998..4471
                     /locus_tag="NOB74_002384"
     CDS             3998..4471
                     /locus_tag="NOB74_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCI1221527.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            4468..6600
                     /gene="feoB"
                     /locus_tag="NOB74_002385"
     CDS             4468..6600
                     /gene="feoB"
                     /locus_tag="NOB74_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HCI1221528.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            6602..6736
                     /locus_tag="NOB74_002386"
     CDS             6602..6736
                     /locus_tag="NOB74_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HCI1221529.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            6830..7474
                     /locus_tag="NOB74_002387"
     CDS             6830..7474
                     /locus_tag="NOB74_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1221530.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            7661..8854
                     /locus_tag="NOB74_002388"
     CDS             7661..8854
                     /locus_tag="NOB74_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI1221531.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            8847..10574
                     /locus_tag="NOB74_002389"
     CDS             8847..10574
                     /locus_tag="NOB74_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HCI1221532.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            10968..11165
                     /locus_tag="NOB74_002390"
     CDS             10968..11165
                     /locus_tag="NOB74_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HCI1221533.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            11167..11478
                     /locus_tag="NOB74_002391"
     CDS             11167..11478
                     /locus_tag="NOB74_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI1221534.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            11582..>11706
                     /locus_tag="NOB74_002392"
     CDS             11582..>11706
                     /locus_tag="NOB74_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HCI1221535.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
BASE COUNT         3734 a         2017 c         2415 g         3540 t
ORIGIN      
        1 tttttatttt tcgaaaaatt tttgaattaa aataaatcct tattccaatc caatcaaata
       61 atcgtcgtct ttcatcgctt ctacatgacc taacaaatag ccgtttccga cttgtgagaa
      121 gaagtcatgg ttgcttgtgc ctgttgaaat cccgttcatt acgattgggt tgacatcatt
      181 ggcagtatct ggaaagagtg gatccatccc taggttcatc aatgctttgt tggcattata
      241 gcgtaggaat gtcttgactt cttctgtcca gccgattgga tcgtataatt cttctgtata
      301 acgttcttcg ttttcgtaaa gctcataaag aagattgtac atccagtctt ttaacgtttc
      361 ttgttctgct tcaggtaact cgttgaatcc taattggaat ttgtaaccga tgtaggttcc
      421 atgtacagat tcatctcgga tgattagttt gatgatctct gctacgttag ccaatttgtt
      481 gtttcctaaa taataaagag gagtataaaa acctgaatag aacaagaatg tttctaaaaa
      541 gacgctggca attttctttt ctagcggtgt accgtgtttg tagatttcat tgatacgctc
      601 agcttttttt tgcagataag gattcgtatt tgtccagtca aaaatttctt cgatttcttt
      661 tttcgtattc agtgtactaa aaatagaaga ataacttttg gcatgaacgg attccatgaa
      721 ttgaatattg ttcaaaacgg cttcttcatg gggagtgcgg acatctttac gcaactgatc
      781 catgccactt tcagattgga cagtatctag cagtgtcaaa ccgccaaata catgtcctac
      841 tgtatctttt tccaattgag acaatgtacg ccaatcatct aggtcatttg aaagtgggat
      901 acgtgtatct agccaaaatt gctctgtcag cttctcccaa gtggatttat caatgatatc
      961 ttcaatttca ttccagttta ttgcttcata atatgtttct gacatgagaa tgctccttta
     1021 attaaaatat gaataagcga atctatctat gatattagat cacgcagctt tcacattgat
     1081 tgcttccgat ttcttctgca tcatcagtaa aggtacgtac gtaataaatg gatttgattc
     1141 ctttgtggaa agcgtaatgt cttaaaatat tcaaatcacg tgtcgtttgc ttcgttgttg
     1201 tcttccattc ataaatgcct tctgggattt cagaacgcat gaataaagtc aaactcatgc
     1261 cttgatcgac gtgttgttgt gccgttgcat aaacatcgat tactttacgc atgtccatat
     1321 cataagcaga agtgtaatac ggaatcgtct cattggatag ataaggcgct gggtaataaa
     1381 ttttaccgat tttcttctct tggcgttctt cgatcatgcg agtgatagga tgaatacttg
     1441 cactcgtatc gttgatatat gaaattgagc catttggtgc tactgccaag cgattttgat
     1501 gatacagtcc atctttcatt actgcttgtt tcaaagcatt ccaatcttca gcagttggga
     1561 taaaaatgcc ttcaaacaat gctttgactt tttctgattt tggctggaat tctccagtta
     1621 cgtatttttc gaaataagtg ccgtcagcat aagctgattt ttcaaaatta tggaaaactt
     1681 gttttctttc acgagcgata ttgttgcttt caacaagtgt ccaataattc aacagcatga
     1741 agtaaatatt tgtaaagtct aatgaatcct ctgagccata ttccatttgt tcttttgcaa
     1801 gataagtgtg taagcccatg gcacctaatc caatcgtatg attcagctta tttccgtttt
     1861 ggatcggtgg tacgacatcg atatcagatg catctgtaat aaatgtcaat gcacgagtca
     1921 tcgtacgcac agattgacca aagttagggc tttgcatcaa attcacgata tttgtcgagc
     1981 ctaagttaca tgagatatct gttcctaata cttcatattc ctgtttgccg ttaatcacag
     2041 aaggcgtttg aacttgtaaa atctctgaac ataaattact catgatgatc ttgccatcga
     2101 ttggattctc gcggttcgct gtatcaatat tgattacgta aggatagcca gattcttgtt
     2161 gtaattttga gatttcattt tcaagatcac gcgctttgat tttttgtttg cgaatgtttg
     2221 gatttgcaac tagatgatca tactcagttg taatatttac ataagagaat gggacaccat
     2281 attctttttc gacactatat ggactaaata aatacatatc ttcgttttta cgtgtcaatt
     2341 cataaaattt atcaggtacg atcacgccaa gagaaagagt ttttacgcga atcttttcat
     2401 ctgcattttc tttttttgct gaaaggaaag caataatgtc tggatggaaa acgttcaaat
     2461 aaaccacgcc agctccttga cgctgaccta attgattaga atagctgaaa ctatcttcga
     2521 ataatttcat gactggaacg acaccacttg cagcaccctc atatcctttg ataggagcgc
     2581 cggcttcacg aagatttgat aaagtaatcc ctacgccgcc accaatacgg gacaattgca
     2641 aagcagagtt gattgagcgc ccgatagagt tcatatcgtc agtgacttga gtcaagaaac
     2701 aagacaccaa ttcgccccga cgtttacgtc cagcattcaa gaaagaaggt gtagctggct
     2761 gatatcgttg atggatcatt tcgtctgcaa gagcaagtgc taattcttca tccccgttcg
     2821 caaagtaaag cgcattgaag gctactcgat cttcataagt ttccagataa gcggaaccgt
     2881 cgttggtttt caacgcatat tgagaataaa atttgtaagc agccataaaa gatttgaaag
     2941 aaaaatgttg ctcgtccaaa aattgatata gcttttcaat aaatgatggt gaatacaatt
     3001 gaatgaattc tgcttctata tattcttgat cgatcaagta attgattttt tccataatag
     3061 atggaaaagt catcgtattt ggtttgacat tttcctcaaa aaaggcaact aaagcttctt
     3121 tatccttatt caaagggatt tgaccattga ctggccgatt gatttcatta ttcagcttga
     3181 aataactgac atcttgtaaa tttttaagac tcatacgtac gcccaacctt catttcgtat
     3241 ttgatgatgc ttgattgcaa atcattgcat tgtttttaag ctttaaaaaa ggatttggaa
     3301 gtttgcgaca aaaactggtg ctgtctcaag cccttcaaat ccatgtatca cgttttgatt
     3361 cttttagtca tgttagctgg caagtttacg caactgatca ggacggaatc cgataactgt
     3421 ttctgcatca gaagtaatga caggaacact ttggaatcct tgtgctttca accagtctac
     3481 tgcttcaggc tgttcatcga tattgacttc ttcaaaagca atttgatttt ctgttaaaaa
     3541 ccgtttgacc atcttacatt gcatacaatt atttttagaa aagattttta cgttcatggt
     3601 gagtgcctcc tctaacacat tcttattatc tataatagat agtataaaac tcttagtaaa
     3661 aaagtcaaac aacaaacact acatattgtg ttgtggaaac tgtggaatac taagttttgt
     3721 gtttttgaaa aaagagctga aaacaagtat cgtgtgggaa aatagcaaat ttaatagaga
     3781 aaaaattgtg gaaaactatg aagaaatatt tttttctcat ttttatctat caatactaaa
     3841 gattcgctca taatatcaca agtataattg acattctcaa ttaccgagag tattctatgt
     3901 gagaatgatt ctcatttatt tgcgtaacac gtaagaaaat tagaacatat aatgaatgat
     3961 tttaatacat gatttatttc acaagagagg aatcaatatg cagaccttag cgcaggcaaa
     4021 gcagaatttc gtttatcaag tcgaacgaat cgaaacagaa gaaaaaacaa aacgccattt
     4081 gcaaaatatc gggatcgttg ccggaagtaa aatcgtcgtc gtcaatttat caggcaacaa
     4141 tgccatttta ctggtaaaaa gtcatcgagt ggcagtaagt cgggaaatac taggtcaaat
     4201 ctttgtcaat aaaaagactg cttcctctga aagctggact tctcttgatc aattaaaagc
     4261 aggagagact gggatcgtcg tagcaatcca cggacaaggc gcagtgaagc gacggttaat
     4321 ggatatggga ttgacgcgaa atgtaaaaat agttatccga aaactagccc ctctgggaga
     4381 tccaatcgaa ctgacagtgc gagggtatga actgacgtta cgaaagtcag aggccgaact
     4441 aatcttgata caaagggagg aaaaagaatg aatatcgcgt tagtcggaaa tccaaacagc
     4501 gggaaaacta gcttgttcaa tctcttgact ggttcgaatc aatatgtagg gaattggccg
     4561 ggcgtaacag tagaaaaaaa agaaggatcg ttgaaaaaaa atccgaacat tcatattcag
     4621 gacctacccg gcatctattc tttgtctcct tatacaccag aagaagtgat tgcaagagat
     4681 tatttggttc aggaacagcc tgaactgatc atcaacatta ttgatgctac caatttagaa
     4741 cgaaatcttt atttaactac gcagttattg gatttagaca ttcctatgat cattggtctg
     4801 aatatgatgg atgtcatcaa aaaagaagga aaaaaaatca atctagaaaa gctttcctat
     4861 ggtcttggtg taccagtttt accaatcagc gtattgaaaa agcaaggaat cgaaaaacta
     4921 atcgaaaaga ttcaggagtc tgcaaaaaag cggccttcta ttcctgttcc ctgtacatat
     4981 gatccacgtt tagaagcagc tttacatgaa attgaagatg tactaggaga acaaagcggc
     5041 aagaaacgct ggtatgcaat gaaatatttt gaacgagatc agaaggtaag agaggattac
     5101 gagatagcag tttctcagca aaaagagatc gagcaactga tccagttaac agagaaacta
     5161 ttggacgacg atagtgagac gattctggtc aatgaacgtt atgaatttat tacccaacta
     5221 tgtacactct gtgttgtgtc aaatgattct ttccaattat cgatgagtga caaaatcgat
     5281 cagattgcaa cgaatcgttg gttagccttg ccgatcttcg catttgtgat gtggctgatc
     5341 tattatctgg ctattcaaac agtaggaaca atggggacag attggatcaa tgacacattg
     5401 tttggtacat ggttaccaga acatgttggc agattgttag ctgaatggca agtagcggga
     5461 tggatgcagg agctgatctt gaacggcatc atcgcaggcg tgggagcagt gttaggattt
     5521 ctaccgcaat tgattatatt gtttttatgc ttgagctttc tggaagactg cggatatatg
     5581 gcgaggatcg cttttgtcat ggatcgactt ttcaggaaat tcggtctttc aggaaaatcc
     5641 ttcattccta tgctgattgc tacaggatgt ggagtgccag gcgtcatggc cagtcgcacg
     5701 attgaaaacg agcaagatcg tcgtttgacg atcatggtca caaccttcat gccttgttct
     5761 gcaaagttgc cgattattgc cttagtagca ggggcctttt ttcctcatca atcttgggta
     5821 gctccttctg cctattttct tggtatgact gcaattattt tctctggaat cagcttgaaa
     5881 aaaacacgtt tgtttgctgg agatacagct ccttttatca tggaattgcc cgcatatcat
     5941 tttcctcaat ggtcagcggt cctaagacaa acctatgacc gcagcaagtc ttttgttaaa
     6001 aaagcaggaa cgattatctt tgtttctagt atcgtgatct ggttcagctc ttcttataat
     6061 ttttatgctc aacctgtttc tgaagaccaa agtatcttag cctttttcgg gcgaatcctg
     6121 gcagttgttt ttcagccgct tggttgggga aactggcaag gaacagtcgc agcgattaca
     6181 ggattggtcg ctaaagaaaa tattattggc acatttggta ttttgtttgg tcatgcggaa
     6241 gtatccgaaa atggcagaga aatctggcaa gtgctacaac acacatatac tcccgcagca
     6301 gcttattcat tgttagcctt caatttactt tgtgcgcctt gttttgcggc aattggggct
     6361 atccatcggg aaatgaatgc caagaaatgg acttggatcg ccataggcta tcaatgcggt
     6421 ttagcttatt tagttagttt tgtgatttat cagttgggac acttattgga gggtggacag
     6481 gtagcgttag ggacgtatct tgctatttta ctgatgatag gactcgttta tgttttgttc
     6541 cgtcagccaa aatccaagaa ccagttttat actatattgt cattagaagg agaggaatag
     6601 gatggcgaca ttcttattaa gtgtgttaat ctttggaagt gcaggcgcaa ttgtctatac
     6661 tcgtttaaaa tccggtaaga attgtgatga ctgtcaaaca gcttgcccag taaaaaagga
     6721 acagatcaag cgatgatcag tcgttgcaag aggctattct cccctttttt gcttattttg
     6781 ctagagcata gtaagatgag ggaaagtaaa aaaagaaaga ggaaagaaaa tgtctggaaa
     6841 gaaaaaaatc gtccgcccgc gctaccagca gattgctgtt gatttagccg aacgtatcgt
     6901 tgaaaaccga tataaagtgg gtgagaagat ccatgcccgc tcaacacttg ccagtacgta
     6961 caatgcttct cctgagacta cccgcaaggc tatcaatgtg ctggtagatc ttggaatcat
     7021 ggaagtacgg catggaagtg gggcatttgt tgcttcgaag gaaaaagcaa aagatttcct
     7081 attgcaatat caagatgtac aatccatcca agatacaaaa gcagaaatca tggcaagtgt
     7141 ggagaagcaa caagatgagc tgaatcattt ttctcaatta ttggatcagc tggtcaatca
     7201 aacgaagcga atacataaga tgaatccttt acttccgttt gaattatctt tatcagaaaa
     7261 agcaatgcat ctggaccgtt caattagcga gttgaatatc tggcaggcga ctggcgccac
     7321 agttatcgca atttctcata atgaagaact gcttgtttca cctggcccct atgctaaatt
     7381 tacggcaggg gacatcgttc attttattgg aaatgaatat acactacagc gtatgacaaa
     7441 ctttttttac ccggagcatc agcttgcaga atgattgtgt gaaatattaa aaaaatatta
     7501 acttggctaa accttttatt tacaaagatt tagccaagtt tttttcagtt tggacaagca
     7561 aatttctttc atttttgaca aagtgactac atgatgttaa catagtgtgg tcactttttt
     7621 cagaaagaaa aatgaattta cataaaaaag gagaatttgt ttggtaaaag tagaagtaaa
     7681 acatttaaca aagatatttg gtaaaaagac acaagccgct ttagatatga tgaatgatca
     7741 ccagccgaaa acggagattt taaagaaaac cggtgcaacg gttggtgtgt atgacgtgaa
     7801 ttttgacgta aaagaaggag aaatcttcgt gatcatgggg ctttccggga gtgggaaatc
     7861 cacattgatc cgtctattga atcgtctgat tgagccaact tcgggcagta tctatattga
     7921 tggagaagat gtatcgaagt taagcaaaga agaattgcga gaagtccgtc gtcataaaat
     7981 caatatggtt ttccaaaact tcggtctgtt tccacatcga acgatcttgg aaaatacaga
     8041 atacgggtta gaagtccgtg gtgtacctaa agaagaacga caagaaaaag cagaaaaagc
     8101 attagaaaat tctagtttgc tttcatttaa agaccaatat cctagtcagt tatctggtgg
     8161 gatgcaacaa cgggttggcc tagccagagc tttagcaaat gatcctgaga tcttgctgat
     8221 ggacgaagcg ttctcggctc ttgatccgct gatccggcga gaaatgcaag acgaattact
     8281 ggacctgcaa gccaatgttc aaaaaacgat tattttcatt acccatgatt tgaatgaagc
     8341 tttacggatt ggggacagaa tcgccttgat gaaagacggc gaaatcatgc agatcggaac
     8401 aggtgaagaa atattgacca atccagcaaa tgattatgta cgtgaatttg tggaagaagt
     8461 cgatcgttcc aaagtgctta cggctcaaaa catcatggta cctgcattga cgacgaatat
     8521 cgaatctgat ggaccaaacg ttgcattgac aaggatgcgt aatgaagaag tcagcatgct
     8581 gatggctgtt gacagaaaga gacacctgaa agggatcatc actgcagatc aagcgttaga
     8641 agctaggaag caaaaacgtc cattgatcga cttcctagat gaaaatgtga cggtgattgg
     8701 gaaagacatg gtggtaagtg atattttcaa tattatttat gactcaccga ctccacttgc
     8761 agttgtagag gatggaaaat taaaaggtgt cgtcatccga ggtagtgtga ttgaagcatt
     8821 agcagaaaca agcgaggtga gtgaacatga ataatctatt gaactatcaa ttaccagtgg
     8881 caaactgggt agaaaatatc acagaatggt ttacgacaac tttttctggc ctattttcat
     8941 ttttacaaac gattggacag gcagtgatgt cggggattac aaatttactg ttagtgattc
     9001 cagctccttt gtttatcttg ttattgacgg tagcagcttt ctttatttct aagaaacgtc
     9061 caggacttac gttgttcaca ttaatcggtc tatggtttat ttataaccaa ggtctatgga
     9121 atgatttgat gaatactgtc acacttgttc ttttatctag tgtgatctcg atcatcattg
     9181 gggtaccatt agggatcttg atggcaaaaa gcagtaaagc ccaaagtatt atcaaaccga
     9241 tccttgactt tatgcagaca atgccaggat tcgtttattt gattccagca gttgcatttt
     9301 tcggtatcgg gatggttcca ggggtatttg cctcagtcat ctttgctctg ccaccaaccg
     9361 ttcgttttac gaatttaggg attcgacaag ttcctaaaga attagtagaa gcttctgatt
     9421 cattcgggag cacaagtcgt caaaaactat tcaaactaga attgccttta gctaaaagta
     9481 cgatcatggc agggatcaat caaacaacaa tgctgtcact ttcaatggtc gttattgcct
     9541 ctatgatcgg tgcacccggc ttaggacgcg gcgtattatc agcattgcaa agagcacaag
     9601 tcgggaatgg atttgtcaac ggggttgcat tagttatctt agcaatcatc attgaccgtt
     9661 ttacacagca tttgaaccag ccaaacaata aaaaagctgc aggagcaaca acacagaaaa
     9721 gtaaaaaacg tcaaggactg atcattggtg ctgtagtagt agtgatctta ggtgcgattg
     9781 gtatagggag tttttcatct gccaaagaaa caaaacgtat caacttatct tatgttgaat
     9841 gggatacaga agttgcttca acaaatgtag tcggtgaagt attgaaacaa atgggctatg
     9901 atgtaacgat gacgccatta gataattcaa tcatgtggaa atctgtttca aatggcgagt
     9961 cagatgccat ggtttcagct tggctaccta aaactcatgg ttcacaatat gcacaatata
    10021 aagatcaagt cgaagaccta ggtgccaatt tgacaggagc aaaagttggt ttagcagtgc
    10081 cagcctacat ggatgtaaat tcgatcgatg agttaaccga tcaggcaggt aagaaaatca
    10141 taggaatcga gccaggagct ggtgtagtta cggctgctga aaacacgatc caaaaatatg
    10201 acaacttgaa agactggaaa gtagagacat cttcttcagg agcaatgacc gttgcactag
    10261 gtcaagcgat caaaaaacac gaaccaattg tagttacagg atggacacct cattggatgt
    10321 ttgccaaata tgatctgaaa tacttagaag atcctgaaaa cggaatggga agcgaagagc
    10381 agatccatac gatggttcga aaaggattga aagaagacca gccagaagct tacaaagtat
    10441 tagacaattt ccattggtca gaaaaagata tggaaaaagt tatgttggaa atcaacaatg
    10501 gaaaagatcc acagcaagca gcaaaagact ggatcaaaga gaaccaagaa ttagtcgaaa
    10561 gctggaaaaa ataaaaagac agacacgaaa taaatggagc ttccaaaatt ggatcaaata
    10621 tccaaatttg gaagctccat gttcgtctct atcttttttg tctataaaaa aagagaatgc
    10681 gtagctcatc ttcgaaacgt tcaaagacgc cgacaaacta ttatgaattt atgggtgcga
    10741 gtcaaagaga tcgatcgtag gtatgaaaga ctaatgtgat taaagtttat tatgtacgaa
    10801 gtgcattctc aaaaaatatt aaagaatata catagtttat atacttaaaa gtgattaaat
    10861 tcttattcag gaattatttt gctacgtttc aagaaggaat tgttttttga aatttaatga
    10921 atgttagaat aatagtctaa aaacattaat ttaggggtga ttagattatg aaacatttaa
    10981 aaattttgtc tattaaagag acacaactta tctatggggg taccactcat agtggaaaat
    11041 attatggaaa tggagtgtat tgcactaaaa ataaatgtac ggtcgattgg gccaaggcaa
    11101 ctacttgtat tgcaggaatg tctataggtg gttttttagg tggagcaatt ccagggaagt
    11161 gctaaaatga aaaaaaatgc taagcaaatt gttcatgaat tatataatga tatatctata
    11221 agtaaagatc ctaaatattc tgatattctt gaggttttac aaaaggtata tttaaaatta
    11281 gaaaaacaaa aatatgaatt agatcccagt cctttaataa atagattggt gaattatcta
    11341 tattttactg cttatactaa taaaataaga ttcactgaat atcaagagga attaataaga
    11401 aatttgagtg aaattggaag aactgctgga ataaatggtt tatatcgagc agattatgga
    11461 gataaatctc aattttaatg atacttataa tattaaatat gtctcaaaat tttttgatta
    11521 gaaaaatagg tatattgaat cagtgacata aaagtattta tagtttgtag ggggaatcgt
    11581 aatggaagaa aaaaatagac taaatgctaa acaatgttca gatcaagagc ttaaaaaaat
    11641 taaaggaggt gctggaacaa aacctcaagg aaaaccggca tcaaatttag tggaatgtgt
    11701 tttttc
//
LOCUS       DAIGWC010000083        11511 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.084, whole genome shotgun sequence.
ACCESSION   DAIGWC010000083 DAIGWC010000000
VERSION     DAIGWC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.084"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            149..2314
                     /gene="acm"
                     /locus_tag="NOB74_002393"
     CDS             149..2314
                     /gene="acm"
                     /locus_tag="NOB74_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HCI1221536.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2586..3071)
                     /locus_tag="NOB74_002394"
     CDS             complement(2586..3071)
                     /locus_tag="NOB74_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HCI1221537.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3161..3506
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3551..4192
                     /locus_tag="NOB74_002395"
     CDS             3551..4192
                     /locus_tag="NOB74_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI1221538.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4211..4846
                     /locus_tag="NOB74_002396"
     CDS             4211..4846
                     /locus_tag="NOB74_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI1221539.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4864..5679
                     /locus_tag="NOB74_002397"
     CDS             4864..5679
                     /locus_tag="NOB74_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1221540.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5998..7434
                     /locus_tag="NOB74_002398"
     CDS             5998..7434
                     /locus_tag="NOB74_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1221541.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7623..10070
                     /locus_tag="NOB74_002399"
     CDS             7623..10070
                     /locus_tag="NOB74_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCI1221542.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10300..11367
                     /gene="rlmN"
                     /locus_tag="NOB74_002400"
     CDS             10300..11367
                     /gene="rlmN"
                     /locus_tag="NOB74_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HCI1221543.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
BASE COUNT         4010 a         1879 c         2476 g         3146 t
ORIGIN      
        1 catatttatt ttttataaat atttgtaaaa taactatcaa ttttttagtt aaaagattgg
       61 aaatgagtgg gggaggaatt gaagaaagga tttttgagag atgatatagt aggttttatt
      121 tttagttaaa ataggggaga tagaaaaaat gaaaaagtgt agaaatatta ttttatcaat
      181 gttatttatt attactaata taacatcact gattcctgtt catgtctatg cggatgcagg
      241 cagagatatc agcagtaatg tcacttcgtt gaccgtggac ccaacgaata ttacagatgg
      301 aggaaacata aaagtaaaat tctcgtttga cgaaaaaaaa caaaatatcc aaccaggtga
      361 ttatctttgg atcaattggc caagtgaagg aaatattcgc ggtgaaggat tccaaaaaga
      421 aatcccatta atgattgaaa ataaaaatgt tggaacttta acggtcagaa aagattctgc
      481 gcaggttgtg tttaatgaaa atattaaaaa cctagactca gtagaaggtt gggggcaatt
      541 tgagatacag gccagaaacg taaccgatac cggtgaagaa aatacgggac cattcaccgt
      601 gacgagcggt gataaaacag ctactgtaaa tgtgacaaag ccagcttctg gttcttcttc
      661 tagcgttttt tattataaaa caggagacat gctacctgaa gatactaagc acattcgatg
      721 gtttttgaat attaacaata acggcactta tgttgaacaa ccagttaaaa tcagtgatga
      781 aatccaaagt ggacaaagat tagatccaag tacgtttgaa attaatcaaa tacacttagg
      841 tgaacagaag gtttatagag gagaagaggg aatccaacaa tttttacaag atttccccag
      901 cgctacattt aatttttcag taactgataa ttacattgaa ataactatac caaaaaactt
      961 tgtcaatctt aggaaaataa tggtgagtta taagacgatc atagaaaacc cagaacaaat
     1021 aaattttgag aatcattcgg aagcttggtt taaagaattt aataaacctg ctgttgatgg
     1081 agaaagtttc aatcatacag ttaaaaatat ttcagcttct ggtggagtca acggtacagt
     1141 tagaggcgaa ttgaagattt tcaaatatat caatgacaca gagattggta tcccaaatgt
     1201 gactttcgaa ttaagacgag cagatgaaca gcctattcaa ggacagtcta gtatcctgtt
     1261 gacttcgaat gaacagggag aagctagtat caaaggcctg caagtaggag actatgttgt
     1321 aaaagaaaaa gaagcaccca attggattga ttttgatcca ctaagttcaa atgaactcaa
     1381 attctccata aacgaaaatg atacagaggg agtcagttta cctatttata acaagaaaaa
     1441 ggttacgaac atcacagcaa ctaaaatttg gaacggtgga accactccaa gaccgagtat
     1501 ttattttaaa ttattcagag caagtacaaa caattgggaa ccagttcctg atgcagaaac
     1561 aaaacgatta gacaatggaa taacttcagt gacttgggaa gatatccaac agtatgatga
     1621 tagtggaaac gaatatacgt ttaaagtgca agaagtagat caaaacggaa atgattatgt
     1681 cccttcaggt tatcaaaaaa ttgaaaacgg gctagtcgtt acaaatgaga ataaagaagt
     1741 catttcagtc tcaggacaaa aaacatggga agacaatgag aaccaagacg gcaaacgacc
     1801 gacgacgatc acagtaaatc tattagccga cggtcaaccg atccaacaca aagaagtaag
     1861 tgaaaaagat gattggcgct atcgtttcac aaatctgcca aaatacagag acgggcaaga
     1921 aatcatctat actgtaacgg aagacaacgt gcccgaatac agtacgacga ttgacgggta
     1981 taacatcaaa aacagttata caccggaaaa aacaaatata tctataccag gtagccatat
     2041 aacaccgtgg aaaaattttc cagagaagac agagagagag aaaattagaa atctattctc
     2101 tcaaaaattg caaatatttg ctcatacagg agaatccagc gaacaaagaa gcaattatat
     2161 tagtaagaga gctgtaccta aacagataac aaataaatca aaaagcattc ttcctaaaac
     2221 aagtagtaaa aaatctagtt ttgctgtaat cattggttta ttgatagtaa ctatctgtgc
     2281 tgggatattc ttacaaaaat ataaaaaagt ttagttagaa tataatattt tttgttaaat
     2341 atgactgaaa tcaaaagaat aaaattccga tttataatcg aaaaaagaag catttttata
     2401 tatgcttctt ttttcgtaga atcaataaat atggatttgg ctaactatgg aagaatactc
     2461 gtattagttt tcagcgttca tactagttgt tacattgttt gattggccaa aagaatttct
     2521 gatatatttt gtgctaaata aagaaaaaga cgcttgaatt gggaaataag aaaactactc
     2581 tatcattaca aattttcata aactggcaga tgttctaagt aaacaagtat cttttcaaag
     2641 tcggaaaaat ccataatcaa cgtagtggta ttgatatttg gatgaaagcc tacggtatct
     2701 tgacgatcaa tagcagcatc gatcacgact tggatttttt tctctttgtc gtgcatcaat
     2761 gctaatggag tcactgtacc tgctggaacg cctaggaggt caggaagctg ttcttcagaa
     2821 acaaaagata agcgcttttc ttttaattgt tcagctagtt gttttaaatc ggcgtgcttt
     2881 tcatcaggca agatgacaag atagatttgt tttccttttc ttgatttcaa taatagattt
     2941 tttacttgcg gaccaggtag ggaaaaaggg acatttttga ctgacgtaat cgcaggatga
     3001 tcgacttttt gaaaagagat acccagtttt tttagtagtt cataagcttc ttgttcggtt
     3061 gcacgactca tcgcgcatca ccctcctttt tttattagtg tatcataaaa aagagttgac
     3121 aaatgaaaaa taatcatgta aattacacgt aaagttaaaa caaatgacat cgaaaagaag
     3181 agtagccgtt aggtgttttt agagagtctc tggttggtgg aaagaggcag cagttaaccg
     3241 tgaaacacat cttggagtcg attttctgaa gcgtatagta ggaaaatccg gggagcccgt
     3301 tacagctgcg gtcgttgcta gatgaccaga taaggctggc ttttccgtga ggagtcggta
     3361 aaaaaaggtg gaaccacgtg attaacgtcc tttgatcttc ggatcaaagg actttttgtt
     3421 ttcatctgaa cggcaacgac tgtgtgaggt tttttctgca aggaaaaaat aaacagaggt
     3481 ggaaccacgt ataatacgtc ctcttggcat ttgccaagag gattttttta ttttaaagga
     3541 ggaaaagaag atggagtatt tgattgaagt tatgccgcaa ttattagtag gagcactcac
     3601 aacattgaaa ttatttttat ttaccttgat tggctcatta ccattaggga ttgttttagc
     3661 attaggattg tctttgcatt ttaagccgct acgctacttg cttcaaacat atgtatgggt
     3721 tatgcgggga acaccgctgt tgttgcaact gatttttatt ttttatgggt tgccgacgat
     3781 tgggatcgtt tttgatcgtt tcgaagcagc actcattgcc tttatcttaa actatgcagc
     3841 ttattttgca gagatctttc gtggagggat acaatcgatt cctcaaggtc aatatgaagc
     3901 agcgcaagtt ttgcaattaa gtccctttca aacggtgacg aaaatcgtca tcccacaagt
     3961 gacaaagatt gttttacctt ctgtagggaa tgaagttatc aacttggtca aagattcttc
     4021 cttgatctat atattaggtt taggtgacgt aatgcgtgct gggaaaatcg cgatggaacg
     4081 cgacgcgact ttactgcctt tgctaggcgt ggcaatcatc tatcttacat tgactggtat
     4141 tctaacaatc gtaatgaaac aagttgaagg aaaattaaat tattaccgct aactgatagg
     4201 aggaagaaat atgattgaat tgaagaaagt gaacaaagca tttggtgaaa aaaaaataat
     4261 caaagatttg aatctaatca ttccagatgg gaaaacatta gctatcgtag gtccttccgg
     4321 tggcggtaaa accacgcttt tacgtatctt ggctggctta gaaagttctg acagcggaga
     4381 attttattta gacggtgtac cgttcaaccc attcgagctt aaaatgaaag aacaagttgt
     4441 aggagtcgta ttccaagact tccagctatt tccacatctg aatatttttg aaaacattac
     4501 cttagcacca aaaatggtat tgaaacagac aaaagaagaa tacaccaaaa aagcagaaga
     4561 attagcggct tcattaggga ttagtgattt attgaatatc tatccttatc agctttctgg
     4621 cggacaaaaa cagcgggtag cgattgccag agcattggct atgaatccac gggtattggc
     4681 ttatgatgaa ccaacaagtg ctttagatcc tgaattacgc cagcaagtcg agcgtttgat
     4741 cctatcattg aaagaagatg gggtaaccca aattattgtc acccatgatt tagtatttgc
     4801 agaaaatgtc ggtgatcaat tactaaaagt ttccccaatt cattaagaaa ggagaagata
     4861 gagatgaaaa aaaccagttt tctattcgct ttgatcgcag gtcttcttct ttttgcaggc
     4921 tgttcgaaca aaaaaacttc agcagataat tgggcgacta tcaacgaaga gaaaaaaatc
     4981 gttataggtt tagacgatac atttgttcct atgggattta gagataaaga cgggaagctc
     5041 acaggatttg atattgattt agccaaagca gtctttgaac aatatgggat tacggtagac
     5101 tttcagccca ttgactggtc aatgaaggaa tttgaactga acaatggaac gatcgatttg
     5161 atatggaacg gctattccaa aacgccggca agagaaaaga aagtgcaatt tacaaaacct
     5221 tatatggaaa acgatcaagt gctgatcaca cctaaagaat caggaatcac aaactttgga
     5281 caaatgaata ataagagatt aggtgcgcaa aatgggtcat ctggttatga tgtatttacg
     5341 aaacaaccag aagtattaaa agagatagtc aaaaaccaag atgctgtttt gtatgatagt
     5401 tttaatgaag cattgatcga tctgaaaagc agacgggtcg atggtctgct gatggataaa
     5461 gtatacgcag actattattt gaaacaaaga aacgaactag aagacttcaa cataacaaaa
     5521 ggttcttatg agagtgagga ttttgcagtt ggtgcacgca agtcagatag tacattagtg
     5581 aaaaaaatca atgaagccct agatcaacta gagaaaacag gtgaattcca aaaaatatcc
     5641 gataaatggt ttggcgaaga tgttacgccg agaaattaac aaatagggga ctgtgacaaa
     5701 agacgtgtca cagtcccttt ttccgaataa acagtgttct cctgccaact ccttgtgact
     5761 cggagctgaa tggcaggctc acaacctctt ggtaaacggt gttcaaaagc cagtttttcg
     5821 gtattaagcc aaatttatgc aaaaatgtag aaagccattt tcacaaaatt tttcttacta
     5881 ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg ttgtggaagg
     5941 ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa gagatgaatg
     6001 gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc ttctgcagcg
     6061 tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg ggatcgattt
     6121 gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt agaccactat
     6181 catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc ttaccgcttc
     6241 tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca agctgggctc
     6301 gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc tatgttgact
     6361 ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg ggaatcacgt
     6421 cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt ccgcgggaaa
     6481 gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg ttatttgtta
     6541 gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa ccatattgct
     6601 aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc tggaaaaatc
     6661 ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga aaatgttctg
     6721 gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta tatgtgggga
     6781 aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc aacgattgaa
     6841 gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat caattactat
     6901 caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa aatgaatacg
     6961 acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa aaaagttgag
     7021 aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg attaaggatc
     7081 ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga aaatggctta
     7141 ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg aatcaattac
     7201 ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga agtcctaggc
     7261 tattgcacct ggtcttatac agatttgctt agctggctga acggttatca aaagcgatat
     7321 ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg atataagaaa
     7381 gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct ttagttcaca
     7441 tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata aaatcattta
     7501 gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag ttctttcaaa
     7561 caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat gagggataat
     7621 aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa acgaaaaagc
     7681 aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg attttatttg
     7741 ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac ggctttcgga
     7801 tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta ggattttgga
     7861 ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt ggcggcatac
     7921 tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa ctccatactg
     7981 gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata aaacaaagtc
     8041 aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat tttacttact
     8101 tcttgattgc acagcctgga agttatttag cagcagtgct attactggca ggaggagcat
     8161 tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca attggagaac
     8221 gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa gcggcaaagg
     8281 aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct gcaaaagaag
     8341 ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag caaagggaaa
     8401 atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta agttttgttc
     8461 caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca gtaccagata
     8521 caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag gatgacggta
     8581 cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa ttaccgacag
     8641 ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa aaaattgaaa
     8701 aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc aaggtcgtca
     8761 aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta ggggtaaaag
     8821 taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg aaagatgtcc
     8881 ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca aatggaaaga
     8941 tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca gataaattac
     9001 tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat ctttcgaaga
     9061 tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca attaatggga
     9121 ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg atgatcgatc
     9181 cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg ccggtcgtga
     9241 cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg gaagaacgat
     9301 atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa tttgttcaac
     9361 agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta gtgatcgtag
     9421 atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg attattcgtt
     9481 tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa cgtccaagtg
     9541 tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca tttgcggtat
     9601 caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag ctcttagggc
     9661 gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg caaggagcat
     9721 tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag caagaagctc
     9781 attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct ccagaacagc
     9841 cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa acggcaagta
     9901 tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt ttagtagatg
     9961 aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg aaagtattca
    10021 ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa aacttgtgtg
    10081 atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata ccaaaagaaa
    10141 aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt agtttttgtg
    10201 agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg aatcatgtat
    10261 agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca gtccatttat
    10321 ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa aaaattccga
    10381 gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac agaaatgacg
    10441 aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa tcctctaaaa
    10501 cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga actccctgat
    10561 aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt ttgtgtgacg
    10621 acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct caaaaagaac
    10681 cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca ttattttgat
    10741 gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg tgagccattt
    10801 gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa aggattggca
    10861 attggtgctc ggcacattac agtttccact agtggattag cacacaaaat caaggaattc
    10921 gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa taatgaggtg
    10981 cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat ggaagctgtg
    11041 gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat gttgaatcaa
    11101 gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga taagaaaaaa
    11161 ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca atattctcgc
    11221 agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg cgtaaactgt
    11281 gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt gcgaagcaag
    11341 caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa ttaccataaa
    11401 aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag attctatagc
    11461 gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa a
//
LOCUS       DAIGWC010000084        11507 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.085, whole genome shotgun sequence.
ACCESSION   DAIGWC010000084 DAIGWC010000000
VERSION     DAIGWC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.085"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(79..2154)
                     /locus_tag="NOB74_002401"
     CDS             complement(79..2154)
                     /locus_tag="NOB74_002401"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HCI1221544.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDIKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKDHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEV
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="NOB74_002402"
     CDS             complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="NOB74_002402"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HCI1221545.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRF
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARSVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3457..4269)
                     /gene="recO"
                     /locus_tag="NOB74_002403"
     CDS             complement(3457..4269)
                     /gene="recO"
                     /locus_tag="NOB74_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HCI1221546.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFLSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHAYPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKMPEKNMPEKEIPEKEE"
     gene            complement(4412..5311)
                     /gene="era"
                     /locus_tag="NOB74_002404"
     CDS             complement(4412..5311)
                     /gene="era"
                     /locus_tag="NOB74_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HCI1221547.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYTALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5326..5721)
                     /locus_tag="NOB74_002405"
     CDS             complement(5326..5721)
                     /locus_tag="NOB74_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HCI1221548.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQIDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="NOB74_002406"
     CDS             complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="NOB74_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HCI1221549.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6198..8390)
                     /locus_tag="NOB74_002407"
     CDS             complement(6198..8390)
                     /locus_tag="NOB74_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HCI1221550.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNTGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8414..9385)
                     /locus_tag="NOB74_002408"
     CDS             complement(8414..9385)
                     /locus_tag="NOB74_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HCI1221551.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10090..11469
                     /gene="brnQ"
                     /locus_tag="NOB74_002409"
     CDS             10090..11469
                     /gene="brnQ"
                     /locus_tag="NOB74_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCI1221552.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3106 a         2419 c         2102 g         3880 t
ORIGIN      
        1 ttatttatat ttataacaaa taaaccagag aaatagccta ttttgtgcct gttctctggt
       61 ttatttacat attagaaatt attttgtgat gatttgatct aaacttgcta gtgacaaagc
      121 catggcagca atttgactta attgcgttaa tcggttctta cgtactgctg gttcttctgc
      181 catgaccatc gtctgatcaa aataattttc gatcagtggg cgaaggctta caagctgatc
      241 ataattttcg ttgatcgttt ggtcagcaaa gcttgttttc attacctcta ctgctttgtg
      301 cagttctttc tccgcttcgt tttcgaacag ttcagggtct acttctgatt gtttttcaag
      361 ctccgctttt ttcgctaagt tcacgacacg tgtcaaagct tccatcgatg gtttgaagtc
      421 ttcatctgca agatgctgct tgaacaattg tgctgctgca aatacttttg tcagatcttt
      481 ttgttctgcg ttcaaaacag cttcgatgac atcatgacgg atattcttcg ttgtcaataa
      541 ttggcgcaga cggcctttga taaagtcgat cacctgttgt tgtcccgctg acaagccaat
      601 gccaaaacga tccgtatctt tactgataac ttcactaatc gtttcttgca gaacagacaa
      661 aggaaaggcc cattttttcg attcgatgat tcgaacgaca ccatatgctt gacggcgcaa
      721 agcatatgga tcgtttgagc cacttgggat catcccaact gcaaagaaag aaaagatact
      781 atctaattta tcagcaatcg ctaaaacaga acctactgta gtctcaggta aatctccttc
      841 actggatata ggcatgtaat gttcacggat cgctgttgct acggctggtt tctcgccttt
      901 aagcagagca tatttttctc ccatgatccc ttgtagttca gggaattctc ctaccatgtt
      961 ggttactaga tcaaatttat agatttcagc agcgcgttgc agatccatca attcttcctc
     1021 agacagtcct acttgttcgc ctatgatgcg agcgatgact tgtacccgtt gcattttctc
     1081 atagatgcta ccgatttttt catggaaagt aacagttttt aatttttcaa cgtattggtc
     1141 gattgaagct ttcttgtctt cattataaaa gaattccgca tcttctaaac gagcagtcaa
     1201 tactttttga ttgcctcgta ccacattttc caattttacc cgatcgccat tacgagcaga
     1261 aataaaatga ggaagcaaca taccttgatc gttccgtact tcgaaataac gttgatgttc
     1321 tttcatagaa gtgactagta cttcttcagg aacagataga tatttttctt cgaagtcgcc
     1381 agaaaagaca gttggatatt cgactagatt gttgacttct tctagtaaat cttcatctag
     1441 atcaatgatc cagtgatctt tttctgctaa ttcgtttgct tgtgtgatga tcatttcttt
     1501 tcttttttgc ggtgaagcaa taacaaattg ttcatttaat ttttcttcgt attcttttgc
     1561 atgcgcaaat gtcacatctt cgcctaagaa acgatgacct cttgaagctc tgtctgtttt
     1621 gatatccaag atctcaaacg ggattacttc gtcatctaac aatgccacga tccagtgaat
     1681 aggacggata tattcaaaat cgtattctgc ccaatgcatc gttactggga aagtgaggct
     1741 tttaatgaca tctgctaaac ctgtcaatac ttcttttgct tctttgccgt gagtgtattt
     1801 cgttacatag acatattcca cgccttttaa ttctctaaaa gtgatagcat ctgtcgtcag
     1861 accttgtccg cggacaaatc cttccgctgc tttcgtccag tttccatctg cgtccaaagc
     1921 aatttttttg gctggtcctt tgacttcttc ttcactgtct gcttgacgtt ctggaatgtt
     1981 tgttactttg attgctaaac ggcgcggtgt agaaaatgtt tcaatcgtat cataagtcaa
     2041 ttggttttca tctaaaaatt ttgctgtttt ttcttctaat tgtttcatgc ttggtgtgac
     2101 aacatgagca ggcatttctt ccagcccaat ttcaagtaat aagtcttttg ccatcttatt
     2161 cagcctcctt cacgttttct ggatttgctg tgtttttatt caataaaggg aatcctaatt
     2221 tttcgcgttc tgccacaaag attttggcta cagaacgagc catgttgcgg atacgggaaa
     2281 gataacctgc acgctccgtt acggatactg caccgcgggc atctaataaa ttgaatgtat
     2341 ggctgcattt caaaatataa tcatacgctg gatgaacaag attttcatcg atacagcgtt
     2401 tagcttcttt ttcaaaacga tcaaagttgc ttagtagcaa gtcttggtcg cttacttcaa
     2461 aagaatattt ggaatgttca tattctggtt gtttgaagat ctcgccatat ttcacgccat
     2521 cagcccattc taagtcatag acactttcaa cttcttgaat atatgaagca agacgttcta
     2581 gtccataagt aatctcagaa gtaactggtt tacaaggtag tcctccgact tgctggaagt
     2641 acgtgaattg tgtaatctcc atcccatcaa gccatacttc ccaacccaca ccggcacaac
     2701 ccatcgatgg gttctcccag ttgtcttcaa caaaacgaat atcgtgttct aatggatcaa
     2761 ttcctaaaaa acgcaagctt tctaaataaa gctcttggat attttcaggt gaaggtttca
     2821 ttacgacttg aaattgatga tgctgataca aacggtttgg gttttctcca taacgcccgt
     2881 cagctggtcg gcgggatggc tctacataag cagcattcca tggttccggt ccgattgccc
     2941 gtaagaatgt atatgggctc atcgtacctg ctcctttttc tgtatcataa gcttgcatca
     3001 gcatgcagcc gtttgatgac caaaattttt gtaatgttaa aatcatatct tggacggtca
     3061 attttttact catctgtttt gcccctttca atttttaagc gttgctgtca ataagaatac
     3121 aggaaagaaa acgacaaaaa gtccctatgt ctgattacag acatagggac gaataatttc
     3181 gcggttccac cctacttccg aataaagatt cggcagcttc atttatcgta ctcgcaagtg
     3241 cctcttcaaa aatcgtttgg gtccggcttc cactctcccg aactcgctaa accacgtgtt
     3301 ttttactgat cttggtcaat gtacgtattc attttgcagt tttcttgttt atataataga
     3361 tcctctcagt gaacgatcta tttaatctac ggttaataat agacggaagt ccctgtattt
     3421 gtcaaatagt tttgattttt ttgttgtatc tttcatttat tcttcttttt caggtatctc
     3481 tttttcaggc atatttttct ctggcatctt taatacgtgt gcccaagact tcatttgatc
     3541 aatgaacttt ttgcttttta gatgaatacc gacatattca tcatacaact ggtcaatgag
     3601 gtcacggatt gcctgcttcg tttcttcttt caagtggatt ccactgatct tatcataaga
     3661 aatagccgaa aacattcgaa cgaaataaac agcgcgagga tatgcatgat aacggtgttc
     3721 gtccattggc cagtgtttct cgcatatcac gccgccatat ttggaagaat agtcaaattt
     3781 tccttttgtt tccccgcata cgacacagtg cgtccaaatt ggcgcgattc cgaagcgttg
     3841 cagtatttga acttcaaaga tattcgtgat gatttctgca tcatctcctt ggtccatccg
     3901 ctgcagagct tgttgcgtaa attggaataa gtgcgggtca tattgatgat cttcgattgc
     3961 tgcatctact agatttagca aatacgtacc ataaccgctc aaaaagatat cttcttggat
     4021 gttccgaaac gcatggacgt ctttgacact gcttaaaaac gacaaacctt cacttagaaa
     4081 attaccgata tagactgctt cggtaaaggg gagcaaagcc ggagctaatg gctgattttg
     4141 ccgatggatt cctttgatat aaaacatcat tttgccagaa gattccgtaa agattttgac
     4201 taatttatct ttttctttgt aattacggct agataaaatc aagcctttcg attctgcaag
     4261 ctggctcata ttctccctcc taaaaaataa atctggaaaa gcagattctg ccgatccaga
     4321 ttatttatgt tacgatcttt cgctgttttt ctcaacgtac ggatttttat ccagtttatt
     4381 tctataccta acctataaga agtccagaat atcagtactc gtcttttcgg tagccgaagt
     4441 cttgcagata gacttttttg tctcgccagt ctttttggac tttgacccaa agttctagaa
     4501 atactttgtc tcctaaaaga ttttcgatat cctttcttgc tttcgttcct acttgcttca
     4561 gcatttttcc acctttgccg ataatgattc ctttttggct atctctttca acgatgatcg
     4621 tggcctggat atggatttta tcattctcgt ttcgcttcat cgaatcaaca acgactgcga
     4681 cagaatgagg cacttcgtct cgtgttaaaa acaagacttt ctcacggatc aattcagaaa
     4741 cgatgaagta ttcaggatga tcagtcactt gatcatctgg aaaatattgt gggccctctg
     4801 gcatttcact gactaataca tccattaagc gttcgacatt gtttccttct gtagcagaga
     4861 tcggaatcac ttgtgcaaaa ggcatctgcg tcgaataatc ttcgatgatt cccagcaact
     4921 cgtctggatg gatcttatcg attttattga taatcagata aactggagaa tgcacgtttt
     4981 ttagacgttc aataataaaa tcgtctcccc ggccgcgttt ttgatcagca ctgatcataa
     5041 ataagactgc atccacttct ttcaacgcag tgtaagctgc ttctaccata aaatctccta
     5101 gacgatgctt tggtttatgg attcctggtg tatcgataaa aatcagctga gcttctggtg
     5161 tagtatatac tccttggatt ttatttctag ttgtctgtgc cttgtcactc ataatggcaa
     5221 ttttttgacc cacgattcgg ttcaataatg tggattttcc tacattcggg cggccgacga
     5281 ttgcgacaaa ccctgattta tgttctggca tatacgttct cctttttaat taaacaacaa
     5341 atgatatatt ttagggacaa ataaaatcaa cccaatgatg acagcaaaac aagcggtcac
     5401 taaaactgct ccagctgcca tatctttgat ttttttccca atcggatgaa aatgaaaatc
     5461 cgtaaacatg tccactacat tttcaaaaac agtattgatg atctctacta tccaaacgag
     5521 aaaaacagct aaaagcagcc ataaccactc tatccgatca atctggaaaa tcacgcccat
     5581 aaataaagca aggataccga acgcaacatg tttcctcata ttgcgttctt cctcaaaaac
     5641 ggttttgact ccttggacag caaattccac ggacatcagg aaatgtttgt ttttctctac
     5701 gtttttatct tttgagtcca taggcatcca agatctcttt ctgtaaacca aacatttctt
     5761 tctcatcttc tggtgtcata tggtcatacc cgttgatatg caagaatcca tgtaccgcta
     5821 aaaagccaag ttcccgatca tatgaatggc cgtaagcttc tgcttgttca gcagcacgtt
     5881 caatagagat catgatgtct cctagtacac gaggcaatgg attctctcca tcttcaaaaa
     5941 tcactgggat ttcgtcttcg ccttcttctt ccagagcaaa actgatgacg tctgtcggtg
     6001 catcttttcc acggtaatca cgattgatta cttggattgc cgcattgtcc atgaaagtaa
     6061 cagacatttc tgtttcctct ggcagcttta aataagatgc tgcaaattgc agcaagtcat
     6121 cgatttcttt cattttctct tctgagactt ggtttgtttc atccataaag gtaatatcca
     6181 ttatacatcg cttctttcta ttcttcttgt tcttccttta tcttctcaac ttctgttttc
     6241 attttaggat atttgatccg agaatggaag gtgctactta aaccgctgat caatgatttt
     6301 tccacttttc ggatttcttt caaggtcaat ccactatcgt ctaattgacc atcggaaata
     6361 cgctcttcga taagattatg gacaaaactt tcgatttttt cgctcgttgg atgatccatt
     6421 gcccgtactg cagcctcaca actgtcagca atattgacga tccctgcttc acgactttgc
     6481 ggttttggtc caggataacg gaattgctct tctgttactt ccggattgcg ttctttcgct
     6541 ttgatgtaga aataacgcat tagcgtggtt ccatgatgct gtttgcaaat atcgatcacc
     6601 atttgcggca tattataatc ttccaatatt ttggctccat ctgtcacatg tccaaagata
     6661 atatgtttac tgtcttctgg caataagaaa ttgtgcgggt tttccgctcc tgaaggcaag
     6721 ttctcaacga aaaagctagc atgtttgatc ttgccgatat catgataata gcaagctact
     6781 cgagttagta aagaacgtcc gccgatttct gctacagcgt tagcacttag attagctacc
     6841 atcatactat gatgatacgt acctggcgct tcttccagca actgtttcaa taaaggatga
     6901 tttggattgc tgagttcatt taatacaatt acactgtcat cattgaccat caattcaata
     6961 tatgggtgta gaccgatcgt cagcaagaat gagaagagtg caccagtgaa cccgcagaca
     7021 agcattaacc aagtcgttgc atcaccaaag ctcattcctt gatagacgat caaaatgaca
     7081 tccatcatca caggaaaaat aatgacccac atggcagcag ataatccttg ttctgagatc
     7141 cgtttacgtc tgacaatcgt tgccatgagc ccagagaaaa cataagacat caagataatc
     7201 gttagaaagt tcgtgccaat cgaatcataa aaaatgaaaa gtgcggatac tgcttggaaa
     7261 ataccagcca tgatccctgc tcttcgattc aagaaaaagc ttaaaacaag tggtgcaaaa
     7321 gcagcgggat aaaacagcgg gatataagta gcttgttccg tttggaataa ttggaaaaat
     7381 ttcatcagca ctatgctgac tgacatagct gtcacataga aaagaacgta ttttgttctt
     7441 tctcctgtat tttggaattg aagtgaatta taaatcagta cgccgatttg aagcaaaaca
     7501 gctaaaacca tggcaattag cggaaaaatc gaagttgttt gattagtcag tcctagtaat
     7561 tccaattttt tcatagctga agcatcaatt tgattacctt cacgaacaat gatttctcct
     7621 tggaagatca tcactggttg tacagcttct cgtgcggatt gtttcaattc ttctgtcttt
     7681 ttctcattca atacgtcatt cactacgata ccttgatcca ctaagtagcg aatcatttgt
     7741 tgttgtgctg gtgtgacatt caaatattgg atttgctctt ctgcttcttg tttaaaagct
     7801 tccaattcac tttcacgaac ttgtttgctc atctgttcgt caatgagctt cagactctca
     7861 tccctcacag tatgaatctc agtttcagtc atttcaaata tcgtcgaata aaaattgttc
     7921 ggtagttttt gataaaacac aacattttct gcattcacat tttcaaaatt tttcttcagc
     7981 gcggcgatcc gctcttctgt agtaggcttt gggatatttt catcttcctt tgccttatca
     8041 atcttttcgt cataagattt gttgatggca tcattcgtct tatcgatcaa ttcaaatagt
     8101 tgcttgatcc gattgttctg gtcatctgca agatcttttt ggtaagtgta ttctggagtg
     8161 actgcttctg ctgccagttt tcttttttgt tcggtttctt ccgtgttctc gatcgttttg
     8221 ttcgcacgga tactttcttc tgctacttgg ccttctctga aatcattggc cttttgtttg
     8281 acactactaa atgtaacgcc gcagataatg ataaaaaaca agaacagcag gaaaggcaat
     8341 gctgcctttc caagtttttc ttgtagtttc tgcagtgttt tattcaacat gtgcttatcc
     8401 tcctaagcaa agcttattct tgatggagat ctgccttttc ataagctttg atgatttcgg
     8461 caactacagg gtgccgaaca acgtcacttg cttcaaaatt aacaaaatcg attttcttga
     8521 tttgctttaa tgttcgttct gcatgaacaa gaccacttgt tgtccctcga ggcagatcaa
     8581 tctgactcgt atctccattg acaatcattt ttgattgata accaagacgt gtcaggaaca
     8641 ttttcatctg agcaactgtc gtgttctgtg cttcatccaa aataacgaat gcatcatcca
     8701 atgtccgccc ccgcatgtaa gctaaaggag caatttcgat cacgcctcgt tccatcaatc
     8761 ggttcgtatg atctaatcca aaaatttggt ataaagcatc ataaacagga cgcagataag
     8821 gatctacttt ttcttttaga tccccgggaa gaaagcctag attttcccct gcttccacag
     8881 caggccgcgt caaaatgatt ttttgcactt cacctttttt caaggcagcg attgctaata
     8941 ctactgcaag aaaagttttt cctgtcccgg ctggtcctac gccaaatacg atatcatgtt
     9001 tggctaccga ttcgacatat ttcttttggc cgctgttttt tacccgtata ggttttccat
     9061 tacggtcttt gacgatctct tcctcataca tctcaacaaa ataatctaat gtgccttttt
     9121 gccccatttt cagtgccgtc acgacatctg gtgtacttac atggattcct cgtttgatca
     9181 attcctgcaa tgtccgaatg actgaggcag ccaaggaaat ctgggattgt tcgccaatga
     9241 tctgaatgat ttctccacgt gtatggatgg ttgtttctgt tgtttcttca atcagtttta
     9301 tgtgcttgtc gtgtgcacct aaaagcatgc tgacatcatc agcagccgtc aatctaatct
     9361 ctaaagaact agactcttcc gtcaaaaata gacatcccct ttttttcgat tcattctttc
     9421 ctattttacc atactcagaa gaaactatat agcaaataag aaaaggttct aaaagagttg
     9481 cttaaccata agtaccaaga aacgttaaaa aatagctgct tccattctct aaaggtctcg
     9541 tttgaataaa aaaagctgat catgtaagct atgcataaga tagaggacaa gtattccgtc
     9601 taacttagca agtattctct gggtattttt cttgtttcaa aaaaagaaaa caaaatattt
     9661 gaaatattct tgcatttcaa aaaaaacagg tgtattataa cgtcaacaaa taaatataca
     9721 gcaaagcgtc gaggaaaaca gtaggctatt cagtgattta ttcccagtga gtcatgtaag
     9781 tgagaaatga caataaatcg aatagacgaa catcatttcc gagtcaatgt cgaaaacgta
     9841 gatcattgtg gctgcctcca ttatcaggcc agcggataac tttatcgaaa agcgtccgtg
     9901 aatgaagaag cttttttaag cgaaaaaagg tggtaccgtt ctagaatcta gagccctttt
     9961 cccaagtgga aaagggcttt ttttatattt taaggtggtg gttttcatgg aatctgatat
    10021 tagtggtatt tctagtttct gcaacgttta ttttgttact caaaatgata attattggag
    10081 gaaaaattta tggaagaaac aaaaacttat tcatggaagc aattattgat ggtcagttca
    10141 cttatcttcg ggatgttctt cgggtcaggt aatctgatct ttcctgtcca cttaggtcaa
    10201 atggctggat caaactggat cagcgctggt gtaggatttg ccatctcagg cgctcttttc
    10261 ccattattag ctatcttagc tgtagtagtg acaaaaagtg atggtctgta tgacttagct
    10321 aaacctgtcg gaaaatggta tgctgccttg ttcttgatcc ttgttcattt aacgatcgga
    10381 ccattctttg gtacaccgcg gacagcagca actgcttttg aaatggctgc taaacccttt
    10441 ttgcctgaaa aatatgattc attaggtatg tttttattct ctgctctttt ctttttactt
    10501 gcttatttcc ttactgtaca tccaacacgt ttggtcaaat atgtcggaaa gtatttaaac
    10561 tccttgtttc ttgcattatt agctatcatt tttgtcgttt ctttattcca acccatgggg
    10621 aatctaaacc aatctgctgc agattcttat cagacgaacg ctttgacaaa tggcgtttta
    10681 gaaggataca acacggttga tgcagtagct ttacttgctt taagtgtcac ttttgtccat
    10741 gcagttcgtg atcttggttt taaagataaa aaagtcacag aattaacagc aaaagctggt
    10801 agcctgagcg ttgcgttaga agtcatgatt tattttggtc tggtccttct cggtgcgatg
    10861 agtttgaata agatgtcttt atcagaaaat ggcggaactg cactttctca gatcactaat
    10921 ttttatttag gtaacttcgg tgctagcttc ttaggggtaa tggtcacatt aggtgtcttc
    10981 actaccgcta tgggactcgt tgtttctttt gcacaagatt tccataaact gttccctaaa
    11041 gtcagttata tgacatggct gcggttaacg acttttgtct cttttgtcgt tgcgaatgcc
    11101 ggattggata atatcatcca atggtcttta ccagtattga tgcttttgta tccattgtca
    11161 cttgcgttaa tcttgctttc cttaacagca aaattcttcc aaaagagtcc atttgtctat
    11221 caagtaacga tgttcttttc tgccgttcca gccgtattgg atatgttggc aaattcgcct
    11281 gcattagtga gtcagcaaac tgtcgtagca agcttactag gattttatca tcattatgtt
    11341 ccttttgctg cattaggact tggctgggtc gtcccaacgt tgcttggtta cgctggcagc
    11401 ttgctctttt attatgtata tcgcgtatca ggatataaac aagaagcaag tgagttacca
    11461 gaagaataac caaatcaaac acaatttaac ataagagata ttaaaca
//
LOCUS       DAIGWC010000085        10646 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.086, whole genome shotgun sequence.
ACCESSION   DAIGWC010000085 DAIGWC010000000
VERSION     DAIGWC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.086"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            23..646
                     /locus_tag="NOB74_002410"
     CDS             23..646
                     /locus_tag="NOB74_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221553.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="NOB74_002411"
     CDS             1096..2145
                     /locus_tag="NOB74_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1221554.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="NOB74_002412"
     CDS             2142..3023
                     /locus_tag="NOB74_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1221555.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILVICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="NOB74_002413"
     CDS             3026..3796
                     /locus_tag="NOB74_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1221556.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="NOB74_002414"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="NOB74_002414"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HCI1221557.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="NOB74_002415"
     CDS             5107..6270
                     /locus_tag="NOB74_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI1221558.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="NOB74_002416"
     CDS             6387..6797
                     /locus_tag="NOB74_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI1221559.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="NOB74_002417"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="NOB74_002417"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI1221560.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="NOB74_002418"
     CDS             9370..9654
                     /locus_tag="NOB74_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221561.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="NOB74_002419"
     CDS             9814..10050
                     /locus_tag="NOB74_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI1221562.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="NOB74_002420"
     CDS             10047..10445
                     /locus_tag="NOB74_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCI1221563.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3715 a         1772 c         2253 g         2906 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agttatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttat
//
LOCUS       DAIGWC010000086         9952 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.088, whole genome shotgun sequence.
ACCESSION   DAIGWC010000086 DAIGWC010000000
VERSION     DAIGWC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.088"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            43..780
                     /gene="erm(B)"
                     /locus_tag="NOB74_002421"
     CDS             43..780
                     /gene="erm(B)"
                     /locus_tag="NOB74_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCI1221564.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(977..3943)
                     /locus_tag="NOB74_002422"
     CDS             complement(977..3943)
                     /locus_tag="NOB74_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HCI1221565.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            4089..4664
                     /locus_tag="NOB74_002423"
     CDS             4089..4664
                     /locus_tag="NOB74_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1221566.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            4878..5573
                     /gene="vanR"
                     /locus_tag="NOB74_002424"
     CDS             4878..5573
                     /gene="vanR"
                     /locus_tag="NOB74_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCI1221567.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            5551..6705
                     /locus_tag="NOB74_002425"
     CDS             5551..6705
                     /locus_tag="NOB74_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCI1221568.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            6920..7888
                     /locus_tag="NOB74_002426"
     CDS             6920..7888
                     /locus_tag="NOB74_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCI1221569.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            7881..8912
                     /gene="vanA"
                     /locus_tag="NOB74_002427"
     CDS             7881..8912
                     /gene="vanA"
                     /locus_tag="NOB74_002427"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCI1221570.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAFITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            8918..9526
                     /locus_tag="NOB74_002428"
     CDS             8918..9526
                     /locus_tag="NOB74_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCI1221571.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         3089 a         1869 c         2032 g         2962 t
ORIGIN      
        1 tctgtattta tttatagatg taatcacttc aggagtgatt acatgaacaa aaatataaaa
       61 tattctcaaa actttttaac gagtgaaaaa gtactcaacc aaataataaa acaattgaat
      121 ttaaaagaaa ccgataccgt ttacgaaatt ggaacaggta aagggcattt aacgacgaaa
      181 ctggctaaaa taagtaaaca ggtaacgtct attgaattag acagtcatct attcaactta
      241 tcgtcagaaa aattaaaact gaacattcgt gtcactttaa ttcaccaaga tattctacag
      301 tttcaattcc ctaacaaaca gaggtataaa attgttggga atattcctta ccatttaagc
      361 acacaaatta ttaaaaaagt ggtttttgaa agccatgcgt ctgacatcta tctgattgtt
      421 gaagaaggat tctacaagcg taccttggat attcaccgaa cactagggtt gctcttgcac
      481 actcaagtct cgattcagca attgcttaag ctgccagcgg aatgctttca tcctaaacca
      541 aaagtaaaca gtgtcttaat aaaacttacc cgccatacca cagatgttcc agataaatat
      601 tggaagctat atacgtactt tgtttcaaaa tgggtcaatc gagaatatcg tcaactgttt
      661 actaaaaatc agtttcatca agcaatgaaa cacgccaaag taaacaattt aagtaccgtt
      721 acttatgagc aagtattgtc tatttttaat agttatctat tatttaacgg gaggaaataa
      781 ttctatgagt cgcttttgta aattataaaa gaattgtttt aatgcaggta taaaagatga
      841 acccgcacca acaccgccac caattttaga tagctttgat tggtacattt ttagcgctat
      901 tcggggtagc gtcaggaaaa tgcggattta caacgctaag cctattttcc tgacgaatcc
      961 ctcgttttta acaacgttaa gaaagtttta gtggtcttaa agaatttaat gagactactt
     1021 tctctgagtt aaaatggtat tctcctagta aattaatatg ttcccaacct aagggcgaca
     1081 tatggtgtaa caaatcttca ttaaagctac ctgtccgttt tttatattca actgctgttg
     1141 ttaggtggag agtattccaa atacttatag cattgataat tatgtttaaa gcactggctc
     1201 tttgcaattg atgctgtatg gtgcgttctc taagctcacc ttgttttccg aagaaaatag
     1261 ctcttgccaa tccattcatg gcttctcctt tattcaatcc tctttgtatt tttcttctta
     1321 atgattcatc cgatatataa ttcaaaataa agatcgtttt ttctattcgg cccatctcac
     1381 gtaaggctgt agctaagctg ttttgtcttg aataggaacc tagcttcccc ataataaggg
     1441 atgctgaaac tgttccctcc cttatagaat gagctaatcg caaaacatcc tcataatttt
     1501 ctttaatgac ctttgtattt atttgtccac gtaaaatggc ttctagtttt ggatactcac
     1561 ttgctttatc tatcgtaaat aattttgagt ccgataaatc ccttattctt ggggcaaatt
     1621 taaatcctaa taaatgagtc agtccgaata tttggtcagt gtaaccggca gtgtctgtat
     1681 aatgttcctc tatgtttaga tccgtctcat gatgtaacaa accatccaaa acatgaatcg
     1741 catctcttga attagtatga ataatctttg tgtagtaaga agagaattga tcacttgtaa
     1801 atcggtagat ggtggctcct tttccagttc cataatgtgg atttgcatct gcatgtagtg
     1861 atgaaacacc tagctgcatt ctcataccat ctgacgaaga tgttgtaccg tcgccccaat
     1921 agaaaggcaa ttgtaattta tgatgaaagt ttactaatat ggcttgggct ttattcatgg
     1981 catcttcata catgcgccat tgagatacat tggctagttg cttatatgta agtccgggtg
     2041 tggcttcggc catcttgctc aagccaatat tcattcccat tcctaaaagg gcagccatga
     2101 taatgattgt ttcttcctta tctggttttc gattattgga agcatgagtg aattgctcat
     2161 gaaatcctgt tatatgggcc acatccatga gtaaatcagt taattttatt cttggtagca
     2221 tctgataaag gcttgcacta aatttttttg cttcttctgg aacatctttt tctaagcgtg
     2281 caagtgatag ctttcctttt tcaagagaaa ccccatctaa cttattggaa ttggcagcta
     2341 accactttaa cctttcatta aagctgctgg ttctctccgt tatataatct tcgaatgata
     2401 aactaactga taatctcgta ttccccttcg attgattcca tgtatcttcc gaaaacaaat
     2461 attcctcaaa atccctatat tgtctgctgc caacaatgga aacatctcct gcccgaacat
     2521 gctcccgaag ttctgttaaa acagccattt catagtaatg acgattaatt gttgtaccat
     2581 catcctcgta taaatgtctt ttccatcgtt ttgaaataaa atccacaggt gagtcatcag
     2641 gcacttttcg ctttccagat tcgttcattc ctcggataat ctcaacagct tgtaaaagtg
     2701 gctcatttgc ctttgtagaa tgaaattcca atactcttaa tagcgttggc gtatattttc
     2761 ttagtgaata aaaccgtttt tgcagtaagt ctaaataatc atagtcggca ggacgtgcaa
     2821 gttcctgagc ctcttctact gaagagacaa aggtattcca ttcaataacc gattctaaaa
     2881 ccttaaaaac gtctaatttt tcctctcttg ctttaattaa tgcttgtccg atgttcgtaa
     2941 agtgtataac tttctcattt agctttttac cgttttgttt ctggatttcc tcttgagcct
     3001 tacgaccttt tgataacaaa ctaagtattt gcctatcatg aatttcaaac gctttatccg
     3061 ttagctcctg agtaagttgt aataaataga tggttaatat cgaataacgt ttattttctt
     3121 gaaagtcacg gaatgcatac ggctcgtatc ttgagcctaa gcgagacagc tgcaacaggc
     3181 ggttacggtg caaatgacta atttgcactg tttctaaatc cattcctcgt atgtattcga
     3241 gtcgttctat tatttttaga aaagtttcgg gtgaaggatg acccggtggc tcttttaacc
     3301 aacccaatat cgttttattg gattcggatg gatgctgcga ggtaataatc ccttcaagct
     3361 tttctttttg ctcatttgtt agagatttac taaccgtatt aaatagcttc ttttcagcca
     3421 ttgcccttgc ttcccacacc attctttcaa gtgtagtgat agcaggcagt ataattttgt
     3481 tttttcttag aaaatctatg cattcatgca gtagatgaat ggcatcacca ttttccaaag
     3541 ctaattgatg aaggtactta aatgtcattc gatattcact cagggtaaaa gttacaaagt
     3601 cgtattcact tcgaatttct ttcaaatgat cccaaagtgt attttccctt tgaggataat
     3661 gatcaagcga ggatggacta acaccaatct gtttcgatat atattgtatg accgaatctg
     3721 ggatgctttt gatatgagtg tatggccaac cgggataccg aagaacagct aattgaacag
     3781 caaatcctaa acggttttct tccctccttc gcttattaac tatttctaaa tcccgtttgg
     3841 aaaaagtgaa gtaggtcccc agtatccatt catcttcagg gatttgcata aaagcctgtc
     3901 tctgttccgg tgtaagcaat tctctacctc tcgcaatttt cattcagtat cattccattt
     3961 ctgtattttc aatttattag ttcaattata tatcaataga gtgtactcta ttgatacaaa
     4021 tgtagtagac tgataaaatc atagttaaga gcgtctcata agacttgtct caaaaatgag
     4081 gtgatatttt gcggaaaatc ggttatattc gtgtcagttc gactaaccag aatccttcaa
     4141 gacaatttca gcagttgaac gagatcggaa tggatattat atatgaagag aaagtttcag
     4201 gagcaacaaa ggatcgcgag caacttcaaa aagtgttaga cgatttacag gaagatgaca
     4261 tcatttatgt tacagactta actcgaatca ctcgtagtac acaagatcta tttgaattaa
     4321 tcgataacat acgagataaa aaggcaagtt taaaatcact aaaagataca tggcttgatt
     4381 tatcagaaga taatccatac agccaattct taattactgt aatggctggt gttaaccaat
     4441 tagagcgaga tcttattcgg atgagacaac gtgaagggat tgaattggct aagaaagaag
     4501 gaaagtttaa aggtcgatta aagaagtatc ataaaaatca cgcaggaatg aattatgcgg
     4561 taaagctata taaagaagga aatatgactg taaatcaaat ttgtgaaatt actaatgtat
     4621 ctagggcttc attatacagg aaattatcag aagtgaataa ttagccattc tgtattccgc
     4681 taatgggcaa tatttttaaa gaagaaaagg aaactataaa atattaacag cctcctagcg
     4741 atgccgaaaa gccctttgat aaaaaaagaa tcatcatctt aagaaattct tagtcattta
     4801 ttatgtaaat gcttataaat tcggccctat aatctgataa attattaagg gcaaacttat
     4861 gtgaaagggt gataactatg agcgataaaa tacttattgt ggatgatgaa catgaaattg
     4921 ccgatttggt tgaattatac ttaaaaaacg agaattatac ggttttcaaa tactataccg
     4981 ccaaagaagc attggaatgt atagacaagt ctgagattga ccttgccata ttggacatca
     5041 tgcttcccgg cacaagcggc cttactatct gtcaaaaaat aagggacaag cacacctatc
     5101 cgattatcat gctgaccggg aaagatacag aggtagataa aattacaggg ttaacaatcg
     5161 gcgcggatga ttatataacg aagccctttc gcccactgga gttaattgct cgggtaaagg
     5221 cccagttgcg ccgatacaaa aaattcagtg gagtaaagga gcagaacgaa aatgttatcg
     5281 tccactccgg ccttgtcatt aatgttaaca cccatgagtg ttatctgaac gagaagcagt
     5341 tatcccttac tcccaccgag ttttcaatac tgcgaatcct ctgtgaaaac aaggggaatg
     5401 tggttagctc cgagctgcta tttcatgaga tatggggcga cgaatatttc agcaagagca
     5461 acaacaccat caccgtgcat atccggcatt tgcgcgaaaa aatgaacgac accattgata
     5521 atccgaaata tataaaaacg gtatgggggg ttggttataa aattgaaaaa taaaaaaaac
     5581 gactattcca aactagaacg aaaactttac atgtatatcg ttgcaattgt tgtggtagca
     5641 attgtattcg tgttgtatat tcgttcaatg atccgaggga aacttgggga ttggatctta
     5701 agtattttgg aaaacaaata tgacttaaat cacctggacg cgatgaaatt atatcaatat
     5761 tccatacgga acaatataga tatctttatt tatgtggcga ttgtcattag tattcttatt
     5821 ctatgtcgcg tcatgctttc aaaattcgca aaatactttg acgagataaa taccggcatt
     5881 gatgtactta ttcagaacga agataaacaa attgagcttt ctgcggaaat ggatgttatg
     5941 gaacaaaagc tcaacacatt aaaacggact ctggaaaagc gagagcagga tgcaaagctg
     6001 gccgaacaaa gaaaaaatga cgttgttatg tacttggcgc acgatattaa aacgcccctt
     6061 acatccatta tcggttattt gagcctgctt gacgaggctc cagacatgcc ggtagatcaa
     6121 aaggcaaagt atgtgcatat cacgttggac aaagcgtatc gactcgaaca gctaatcgac
     6181 gagttttttg agattacacg gtataaccta caaacgataa cgctaacaaa aacgcacata
     6241 gacctatact atatgctggt gcagatgacc gatgaatttt atcctcagct ttccgcacat
     6301 ggaaaacagg cggttattca cgcccccgag gatctgaccg tgtccggcga ccctgataaa
     6361 ctcgcgagag tctttaacaa cattttgaaa aacgccgctg catacagtga ggataacagc
     6421 atcattgaca ttaccgcggg cctctccggg gatgtggtgt caatcgaatt caagaacact
     6481 ggaagcatcc caaaagataa gctagctgcc atatttgaaa agttctatag gctggacaat
     6541 gctcgttctt ccgatacggg tggcgcggga cttggattgg cgattgcaaa agaaattatt
     6601 gttcagcatg gagggcagat ttacgcggaa agcaatgata actatacgac gtttagggta
     6661 gagcttccag cgatgccaga cttggttgat aaaaggaggt cctaagagat gtatataatt
     6721 ttttaggaaa atctcaaggt tatctttact ttttcttagg aaattaacaa tttaatatta
     6781 agaaacggct cgttcttaca cggtagactt aataccgtaa gaacgagccg ttttcgttct
     6841 tcagagaaag atttgacaag attaccattg gcatccccgt tttatttggt gcctttcaca
     6901 gaaagggttg gtcttaatta tgaataacat cggcattact gtttatggat gtgagcagga
     6961 tgaggcagat gcattccatg ctctttcgcc tcgctttggc gttatggcaa cgataattaa
     7021 cgccaacgtg tcggaatcca acgccaaatc cgcgcctttc aatcaatgta tcagtgtggg
     7081 acataaatca gagatttccg cctctattct tcttgcgctg aagagagccg gtgtgaaata
     7141 tatttctacc cgaagcatcg gctgcaatca tatagataca actgctgcta agagaatggg
     7201 catcactgtc gacaatgtgg cgtactcgcc ggatagcgtt gccgattata ctatgatgct
     7261 aattcttatg gcagtacgca acgtaaaatc gattgtgcgc tctgtggaaa aacatgattt
     7321 caggttggac agcgaccgtg gcaaggtact cagcgacatg acagttggtg tggtgggaac
     7381 gggccagata ggcaaagcgg ttattgagcg gctgcgagga tttggatgta aagtgttggc
     7441 ttatagtcgc agccgaagta tagaggtaaa ctatgtaccg tttgatgagt tgctgcaaaa
     7501 tagcgatatc gttacgcttc atgtgccgct caatacggat acgcactata ttatcagcca
     7561 cgaacaaata cagagaatga agcaaggagc atttcttatc aatactgggc gcggtccact
     7621 tgtagatacc tatgagttgg ttaaagcatt agaaaacggg aaactgggcg gtgccgcatt
     7681 ggatgtattg gaaggagagg aagagttttt ctactctgat tgcacccaaa aaccaattga
     7741 taatcaattt ttacttaaac ttcaaagaat gcctaacgtg ataatcacac cgcatacggc
     7801 ctattatacc gagcaagcgt tgcgtgatac cgttgaaaaa accattaaaa actgtttgga
     7861 ttttgaaagg agacaggagc atgaatagaa taaaagttgc aatactgttt gggggttgct
     7921 cagaggagca tgacgtatcg gtaaaatctg caatagagat agccgctaac attaataaag
     7981 aaaaatacga gccgttatac attggaatta cgaaatctgg tgtatggaaa atgtgcgaaa
     8041 aaccttgcgc ggaatgggaa aacgacaatt gctattcagc tgtactctcg ccggataaaa
     8101 aaatgcacgg attacttgtt aaaaagaacc atgaatatga aatcaaccat gttgatgtag
     8161 cattttcagc tttgcatggc aagtcaggtg aagatggatc catacaaggt ctgtttgaat
     8221 tgtccggtat cccttttgta ggctgcgata ttcaaagctc agcaatttgt atggacaaat
     8281 cgttgacata catcgttgcg aaaaatgctg ggatagctac tcccgccttt tgggttatta
     8341 ataaagatga taggccggtg gcagctacgt ttacctatcc tgtttttgtt aagccggcgc
     8401 gttcaggctc atccttcggt gtgaaaaaag tcaatagcgc ggacgaattg gactacgcaa
     8461 ttgaatcggc aagacaatat gacagcaaaa tcttaattga gcaggctgtt tcgggctgtg
     8521 aggtcggttg tgcggtattg ggaaacagtg ccgcgttagt tgttggcgag gtggaccaaa
     8581 tcaggctgca gtacggaatc tttcgtattc atcaggaagt cgagccggaa aaaggctctg
     8641 aaaacgcatt tataaccgtt cccgcagacc tttcagcaga ggagcgagga cggatacagg
     8701 aaacggcaaa aaaaatatat aaagcgctcg gctgtagagg tctagcccgt gtggatatgt
     8761 ttttacaaga taacggccgc attgtactga acgaagtcaa tactctgccc ggtttcacgt
     8821 catacagtcg ttatccccgt atgatggccg ctgcaggtat tgcacttccc gaactgattg
     8881 accgcttgat cgtattagcg ttaaaggggt gataagcatg gaaataggat ttactttttt
     8941 agatgaaata gtacacggtg ttcgttggga cgctaaatat gccacttggg ataatttcac
     9001 cggaaaaccg gttgacggtt atgaagtaaa tcgcattgta gggacatacg agttggctga
     9061 atcgcttttg aaggcaaaag aactggctgc tacccaaggg tacggattgc ttctatggga
     9121 cggttaccgt cctaagcgtg ctgtaaactg ttttatgcaa tgggctgcac agccggaaaa
     9181 taacctgaca aaggaaagtt attatcccaa tattgaccga actgagatga tttcaaaagg
     9241 atacgtggct tcaaaatcaa gccatagccg cggcagtgcc attgatctta cgctttatcg
     9301 attagacacg ggtgagcttg taccaatggg gagccgattt gattttatgg atgaacgctc
     9361 tcatcatgcg gcaaatggaa tatcatgcaa tgaagcgcaa aatcgcagac gtttgcgctc
     9421 catcatggaa aacagtgggt ttgaagcata tagcctcgaa tggtggcact atgtattaag
     9481 agacgaacca taccccaata gctattttga tttccccgtt aaataaactt ttaaccgttg
     9541 cacggacaaa ctatataagc taactctttc ggcaggaaac ccgacgtatg taactggttc
     9601 ttagggaatt tatatatagt agatagtatt gaagatgtaa ggcagagcga tattgcggtc
     9661 attatctgcg tgcgctgcgg caagatagcc tgataataag actgatcgca tagaggggtg
     9721 gtatttcaca ccgcccattg tcaacaggca gttcagcctc gttaaattca gcatgggtat
     9781 cacttatgaa aattcatcta cattggtgat aatagtaaat ccagtagggc gaaataattg
     9841 actgtaattt acggggcaaa acggcacaat ctcaaacgag attgtgccgt ttaaggggaa
     9901 gattctagaa atatttcata cttccaacta tatagttaag gaggagactg aa
//
LOCUS       DAIGWC010000087         9888 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.089, whole genome shotgun sequence.
ACCESSION   DAIGWC010000087 DAIGWC010000000
VERSION     DAIGWC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.089"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(109..2229)
                     /locus_tag="NOB74_002429"
     CDS             complement(109..2229)
                     /locus_tag="NOB74_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI1221572.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="NOB74_002430"
     CDS             2459..3637
                     /locus_tag="NOB74_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HCI1221573.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="NOB74_002431"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="NOB74_002431"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HCI1221574.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="NOB74_002432"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="NOB74_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HCI1221575.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="NOB74_002433"
     CDS             complement(4990..6243)
                     /locus_tag="NOB74_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI1221576.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="NOB74_002434"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="NOB74_002434"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HCI1221577.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="NOB74_002435"
     CDS             7821..9167
                     /locus_tag="NOB74_002435"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HCI1221578.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="NOB74_002436"
     CDS             complement(9475..9861)
                     /locus_tag="NOB74_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI1221579.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3149 a         1800 c         2025 g         2914 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt gtttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttatta
//
LOCUS       DAIGWC010000088         9874 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.090, whole genome shotgun sequence.
ACCESSION   DAIGWC010000088 DAIGWC010000000
VERSION     DAIGWC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.090"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(22..267)
                     /locus_tag="NOB74_002437"
     CDS             complement(22..267)
                     /locus_tag="NOB74_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HCI1221580.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(382..960)
                     /locus_tag="NOB74_002438"
     CDS             complement(382..960)
                     /locus_tag="NOB74_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI1221581.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1037..1567)
                     /locus_tag="NOB74_002439"
     CDS             complement(1037..1567)
                     /locus_tag="NOB74_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HCI1221582.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1571..2431)
                     /gene="rlmB"
                     /locus_tag="NOB74_002440"
     CDS             complement(1571..2431)
                     /gene="rlmB"
                     /locus_tag="NOB74_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HCI1221583.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2424..2819)
                     /locus_tag="NOB74_002441"
     CDS             complement(2424..2819)
                     /locus_tag="NOB74_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HCI1221584.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2816..4228)
                     /locus_tag="NOB74_002442"
     CDS             complement(2816..4228)
                     /locus_tag="NOB74_002442"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HCI1221585.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4225..4761)
                     /gene="cysE"
                     /locus_tag="NOB74_002443"
     CDS             complement(4225..4761)
                     /gene="cysE"
                     /locus_tag="NOB74_002443"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HCI1221586.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4847..5086)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5083..6543)
                     /locus_tag="NOB74_002444"
     CDS             complement(5083..6543)
                     /locus_tag="NOB74_002444"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HCI1221587.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6713..7870)
                     /locus_tag="NOB74_002445"
     CDS             complement(6713..7870)
                     /locus_tag="NOB74_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HCI1221588.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7904..9274)
                     /gene="radA"
                     /locus_tag="NOB74_002446"
     CDS             complement(7904..9274)
                     /gene="radA"
                     /locus_tag="NOB74_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HCI1221589.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9337..9864)
                     /locus_tag="NOB74_002447"
     CDS             complement(9337..9864)
                     /locus_tag="NOB74_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HCI1221590.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2509 a         2214 c         1784 g         3367 t
ORIGIN      
        1 aatctcaggc tcgtttgctt tttaaactgc ttcagttaaa aattcgatct caactgtccg
       61 agtaagtaca tctgaatagc tgtaagatac tcgttcaaaa gaattttctt caggatccaa
      121 atcaacaacg aatactgaag gataggtttc tgttaaaacg ccgcggcgtt ctgtttgacg
      181 ctttcttcct gtctgagcaa ccaacatgat tgggctgccg atacgacctt ctaaatcttt
      241 cttgattgaa gctaaagttg ttggcataca gttcacctct actatcaact ataccacata
      301 tttttaaaat tttcaagttt accataaaaa aaaaagaaat gcaataaaaa taaataagaa
      361 gctcattaag atttttctaa attattcctc attataaaat ttcaagtgtt tttttatttt
      421 gagttttact ctcccgtaag cgctcattac ttgcttgtga tccattgcta aacattcagc
      481 catgtctaca aaatcaacgc cttgcatata ataatgaaaa attttagctt ctatttttga
      541 aaactggatt tcgcaatttt cgattgcttc ttttaataaa agatgctgaa tcgctaaagg
      601 ttcttgcaat gtgatctctg ctaaaaagtc tggtccttct gtctctattt tttggtcgat
      661 tgagacttca tctttttgat cacgacgctt cagcgcgttc tgcttcctca acagagaata
      721 gatttgattg cttataatgc ttttataata acttccaaag ctaacacctt tgcttttttc
      781 gtaagttctc aatgcctgat ataaagcgat ccttgcttct tgttcccaat cctcagaaac
      841 ataatttctt aaataatagg tgtttttcaa acgtagtaaa agtggaaaat atttttgata
      901 cagggcagca aatgcttctt cgtcaccatt acgtgcagcg cgcaataact cctcagacat
      961 aaaataattc ctccataaat tcgtttatgg aggaatctta tcatcaatga ttcatcgaac
     1021 tgattagaac gatatgttat ttattttttc tcattaaatc gtccaatttt tgggacaatt
     1081 tttttaactg ctcttcattc catggagaat tacgtcggaa atcaataaaa tgcatatctt
     1141 tattttcttg ggctattgtt ttttccgttt tttttatcgt cttatataat tcataagcag
     1201 aagttcgtaa tgctccttgg gaaaagatca tccactgttc tgctaaatcg cttgtcgcca
     1261 ctgtcacttg tgtcaaacgg tcattcagct gaccagcgat tctctcgata taactgtcag
     1321 ccgtttcgtc ttctttcgta aaaacaacat ccaactggta tttcttataa ttttgttgga
     1381 tgcccggaac tagttgggca tcgaagacaa cgatgacttc cattccttca tatttcgcat
     1441 aatttgataa acgatgtaaa agagcttctc ttgcatccgc cattttgtcc tgctttttaa
     1501 gctggacaag ttccggccac gaaccaatca tgttgtagcc gtctacaatc aacagctgtt
     1561 ttttcatggt ctactccccc tgacgttggg aaaaagcctg atacataagc aaaccagcag
     1621 caacactggc atttaagctc tggacgtgcc cggtcatcgg gatcgtcagc aattcatcca
     1681 tttctttttt caatcctgga ctcattcctt tgccttcatt accaatgact aaagcaattg
     1741 atcctttggc attccatttt tggaagtttg tgccggtcat atctgtgcca aatacccaaa
     1801 atcctgtttc tttgagctgt tgcacagctt gtaccaaatt cgtcacgcgt gcaacaggga
     1861 catgttcgac tgccccagtg gaagtctttg ttacgatagg tgtgattcca actgctcggt
     1921 gttttggtat gatcacacca tcgacgccac ttgcgtctgc tgtccgtaaa atcgacccaa
     1981 aattgtgtgg atcttcgatg ctatccaaaa tcaaaaagaa ggggtcttct tttttctctt
     2041 ttgttcgttc aatcagttgg tcaagggata aatattcata aggtgtaatc gcaagaacga
     2101 ctccttgatg cacgccgtga tcgctcaaag tttctaattt ttgtttagga acccatttga
     2161 ctggcacagc ttgttcacgt gcgatttctt tcagttcttc tactttttct cctcgtgaat
     2221 cttcttgaag aaagagttta ttccctcgcc cttgttgtag cgcttctact gcggcatggt
     2281 gcccaaagac gaaattatct tctaatgctt cttcattttg atcagaaact gactgatttc
     2341 gtccagtttg ctttttattt gaatatctat tttgtttttt gtcttcaaat ccacgtttcg
     2401 attgatgttt gtttgttctt tctttaccca tttttttcac caactttctg aatacaccag
     2461 cggatcaatt cttccatccg ctcggtttgt tttgtcaaat gcagatagcc catgagcgct
     2521 tcgaaccctg ttgcgacccg atacgtcgta acatcagcat tttttgcgct cgtatggctt
     2581 ttagcatttc ttcctctgcg ataataaagt tcttcttctt ctgtcaaaag atgttcttcc
     2641 agcatttgct gaatcaaaaa ggcttgtgca ttcgcagaaa cataattcgt tgccgcacga
     2701 tgcagcttat tgggttttgt ttctccttga tcaatcaggt ggtcacgaac atagatttcg
     2761 taaatcgcat ctccaacata agccaaggct aaaccgttca attgtgtgta atctctcatg
     2821 cttctcttct ccatcgggtt ccttgcggtg tatcttctaa taagatccct ttttctttca
     2881 acaaatcacg aatttcgtcg cttcggacaa aatcacgatt gcttcttgct tgatttcgtt
     2941 cttcgatcaa ttgttcaatc tcttcatcta ataactcttc tgctgtaaat aaaataccga
     3001 agatcgaaag ccattgcgag aataaagctt ctccttgtgc caagacagcg gcagaaactt
     3061 tcggctggtc tagataagtg ttcagccact tagcaagctc atagaccact gtgatcccat
     3121 ttgctgcatt aaaatcatcg tccatttctt cgatgaatcg ctgttctaaa ttttctaaca
     3181 aagcgatttt atccgcatca tctgccaaat tctctgaggc agtttcttgg cggaatttca
     3241 aattgtcaaa cgtattcttc agtcgttgta aattggtggc tgcttctttc atcgtcgttt
     3301 cactgtagcg gatcggacga cggtattgtg tggtcgccat gaagaaacgc aagacttgtg
     3361 gatcaacgtt tttgatcatt tcatgtacag tgatgaaatt ccctagagat ttactcattt
     3421 tttcatcgtc ttcgccaatc gttacatagc cattgtgcat ccagtaatta gcgaattttt
     3481 tccctgtttt cgcttcactt tgtgcgattt cattttcatg atgaggaaat tctaaatctt
     3541 gcccgccacc atggatatcg atcgtttctc ctaaatgttt tgttgccata acggaacatt
     3601 caatatgcca accgggacgt cctttgcccc atggtgaatc ccaagaaatc tcgccaggtt
     3661 ttgcttgttt ccataaagcg aaatctaatg ggtcttcttt ttgctgctgt tcttcccctg
     3721 tacgctgact tgctccgact tccagttcat cgatggattg gtcacttaat ttcccataat
     3781 tttcaaattt acgggtacgg taatacacat cacctgaaga ttcataagca tagccttttt
     3841 caaccaacac ttgaataaat gctaaaatat ctggcatatg atccatgact cttggatgca
     3901 gtgtagcagg ctcgacattc aacgctttcg tatcttcttc aaatgctcgg atgaaacgat
     3961 cagcaacttc tggtgctgta atacctaatt cgtttgctgt acggatgatt ttatcgtcta
     4021 catccgtgaa attcgatacg aaatcgactt tatagcctcg atattcaaaa tagcgtcgaa
     4081 ttgtatcgaa agcaatggtg ctacgagcat ttccgatatg gatataatta tacacagtcg
     4141 gtccgcagac atacataccg acatgtccct tttgtatagg gatgaattct tctttttttc
     4201 tggtcaatgt attgtagatt tttatcattc tgatctcctc actttttctc ctttgattcg
     4261 aacgactttt gctggtactc ctaccgctgt agcgtcgtct ggaacatctt tcaacacaac
     4321 ggcacctgca ccgattttgg cgttttttcc gatcgttacc ggtcctaata tctgcgcatt
     4381 cgcagagagc atggctcctt gtttaacagt tgggtgtctt ttacccgttt cttttcctgt
     4441 gccgcctaat gttacgccat ggaataaaat cacatcgtcc tcgatttctg cggtttcgcc
     4501 aatgacgatt cccattccat ggtcgatgaa cacgccagtt ccaatcgttg ctcctggatg
     4561 gatctcaaca ccagttagga aacgccagaa ttgagcattg atcttcgcca ataaaaagag
     4621 ccggtgctga tataaaaaat gagagaaacg atgccaaaac aaggcatgaa aaccagggta
     4681 tgtcaaaacg atctcagctg tcgaacgtgc agccggatcg tttctctttg ctgcatcaat
     4741 cgctcgggta aaccaactca tgactttcca ctcctttcgt aagaatttta tgtaggaaat
     4801 catcttctta taaagaaaag aagcgccttt taaataagtt tccttatcaa aagacgcttt
     4861 ccgcgtggtt ccacttttct tcataatcaa tgattatctc tgacagctaa cgcctgttat
     4921 acgttcttgg ctactttgtt tcctataaaa cagtttttcc tgttttctgt gtttcgccaa
     4981 gaccactccc agaggcattt cggcaaccat tcattgatac cttgcaccac ccggtatctc
     5041 tcttgtaatg atcagctgct tacttttttc tgttcatcgt gtttagttca gtacttgatt
     5101 taaatgtgct aatgattttt cacgaccaag caattcgatc gtttcaggca attctggacc
     5161 atgcatttgt cctgatacag ctacacggat tggcatgaaa agattttttc cttttacgcc
     5221 agtttctttt tgaacagctt tgatggcagc tttgacagtt ggagcatcta ctacttccat
     5281 ttgttctagc tgtgctttga atgcgtggag aacagtagga actgtttcac cagcaagtac
     5341 ttcttttgct gcttcattca atacaggatg ttcattgaaa aatagcgtag acagatcaac
     5401 gatttctgca gcatagctca tttgaggttg atacaggcta acgatcttct tcacccattc
     5461 gattgtcttt tcatctgggt tttctgctac acgtccatca gcgattagat aaggcagaca
     5521 catgtcagta aatgcatcta gatccattgc tttgatgtaa tggttgttta cccattgcag
     5581 ttttttcgca tcgaaagctg cgggtgattt acttaggcgt tttggatcga acattttgat
     5641 caattcttgg tgttcgaaga tttcgtcttc gcccacaggt gaccagccca ataatgcaat
     5701 aaagttgaac attgcatctg gtagatagcc taattcgcga tattgttcga taaattgcaa
     5761 gattgattcg tcacgtttgc ttagtttttt acctgtttca ctgttgatga tcaatgtcat
     5821 atgtccgaag gttggtggtg tccagccaaa tgcttcatag atcatcagtt gttttggtgt
     5881 attggcaata tggtcatctc cacgtaaaac gtgagtgatt ttcatcaaat gatcatcgac
     5941 cgcaacagca aaattataag ttggcatacc atcgcgtttt tgtatgacaa agtcgccacc
     6001 gatattatcg gattcgaacg aaatagcgcc tttcaccata tctgtaaatg cgtattctgt
     6061 attgcgaggc acacggaaac gtacaacaga ttctagacct tgtgcttctt tttctgcttg
     6121 ttcttcaggt gtcaagttcg cacatgttcc tgcgtaatga ggcatttctc ctcttgcgcg
     6181 ttgtgcttcc cgttctgctt ctaattcttc ttctgtgcaa tagcatttgt atgctcgatt
     6241 gctagcaagc agctgatcaa tcagcggttg atagatttct ttacgttcag attgacggta
     6301 agggccgtat tctccaggat tttcaggaga ttcatcccaa ttcattccca accaagcaag
     6361 gttttccaac tggctttttt cgccatcttc gatattacgt ttttggtcag tatcctcaat
     6421 acgaataata aagtctccat cattgtggcg ggcaaacaaa taattgaata atgcagttct
     6481 tgcatttcca atatgcaggt gcccagttgg acttggtgca tagcgtacgc gtactttcgt
     6541 cattttcttc ctcttctttc aaactagact ttgactaaca gcaaaaattc cgtcagttac
     6601 ggcttctcaa atatcattta tttaaagcca ctcagcacaa attttacctt ttctaaggta
     6661 aatagtaaag ccaactggtt gaatttcctt accagttggc tgaatttctt ttttattttg
     6721 attgtttagt ctttttctct gtctcttttt tattgtcgat tcctcgtcct gcatgtgcag
     6781 gtttagcaaa gatcatgcgt ccagcagctg tttgaagggc acttgttaca acgacttcga
     6841 tacgttcatt catgtaatgc tgtccatctt ctacgacaac catcgtgccg tcatcaaggt
     6901 aggctactcc ttgttggcgt tctgtcccgg cttttactac tagaacattc atcgtttcac
     6961 cagggatgac gactggtttt acggcatttg ccaacgcatt gatattaaga acaggtacat
     7021 tttggaattc agagacttta ttcaagttat agtcattggt tacaatgaca ccatctaaaa
     7081 gcttagccaa tttgatcaat ttgctgtcta cttcactgat atcttcaaag tctccatcgt
     7141 acatttcgac agatataccc tcttcttttt gcaaggcatt taggatatct aatccgcgac
     7201 gaccacgcac acgtttcaaa ctatcccctg agtccgcgat gtattgtagt tcgtaaagaa
     7261 caaaattagg gatcatcaag gttccttcta agaatccagt ctttgtaata tcataaatcc
     7321 gaccgtcaat gatcacgctt gtatccaaga ttttatattt atggaaattt tctcctgatt
     7381 ttcgttctaa cagttgactc tcaacttgac tagctgtttc ttgctcgatt tttttgcttc
     7441 gtgaaccaaa aactttcttc cattcttcga ttcgtgtcgt tcccattctc aatcccagat
     7501 agcctaagat gatcatcagt aaaatcggca atacactatt gacgaatgga atttccatat
     7561 tgtaaagagg ggtcgagatc acaacaccta aagtcaatcc gatgatcgca ccgatcgcac
     7621 cgaagagaag ataagtcaag ctgacctcac ttagtttttg ttctacttgt ttgataatag
     7681 ctgagatatg tttggccaac agcaaagata ataaaaagaa aataagtgcg cctaacaggc
     7741 tgttggtaaa tgtattattc agccatccgt ttgactgttg accgattgcc tgccaagctg
     7801 agggtaaaaa tgaaataccc aagcttgcgc cgacaatgat catcagcaaa gtaatgacac
     7861 gtttttgcat cgtttttcct ccgtttcgac aatcatttat tagttagcgg aacacacgct
     7921 tcaacgtttc agccaaagtt gctactccaa ctatctcgat tccttttggc gcttcccagt
     7981 tacctaagtt gtttttaggt aggtatactt ttgtgaagcc gagtttttgg acttctttga
     8041 ctcgttgttc aatatgactg acacgtctga tttctccagt cagtccaatt tcaccgatga
     8101 aacattccgt tggctgtgtt cctttttctt tatagcttga agcaatactg acagcgatag
     8161 ctaaatcaat cgctggttca tttaatttta ccccacctgc agcttttaag taagcatctt
     8221 gattctgaag aagcaaccca gctctttttt ccagcactgc catgatcaga gatacccgat
     8281 tgaaatcaag acctgttgtt gttcgtttgg catttccgaa catagtaggt gtgactaatg
     8341 cttggatctc taccaaaatt ggacgtgtcc cttccattgc cacaacgata gcagagccag
     8401 ttgcaccgtc taggcgttct tctaagaaaa tctgtgaagg attagcgact tcttccaatc
     8461 catgctcatg catttcaaaa atcccaatct cattcgttga gccaaatcgg ttttttactg
     8521 ctcgcaaaat ccgaaaacta tgatgttgtt caccttcaaa atataacacc gtatccacca
     8581 tatgttctaa cattcttggg ccggcgatcg agccttcttt ggtaacatga ccgacgataa
     8641 aaatggctat cccatttgtt ttagcgattt tgagtagttc tgcagtggtt tctcttactt
     8701 ggctgacact tcctgccaca cttgtgatgt ctggctgcgt catcgtttgg atggaatcaa
     8761 tgataacata atcaggggag atatgttcga tggcacgact gatttcgttc atatctgttt
     8821 cagcgtatag ataaaattct gtgttgatac ttccgaggcg ttccgcgcgt aattttatct
     8881 gctctgcgct ttcttcgccg gatacatata agacttttcc gcctatggct gctaattgct
     8941 gagaaacttg taacagcaaa gtggatttcc cgatacctgg atcgccacca atcaagacca
     9001 tagaccctgg caccacacct ccgcctaaca cacggttcag ttcttctaat tttgttttga
     9061 tccgaggttc ttttttaggg acgacgtctg cgatttttgt tggttttgct ttttctcctg
     9121 tcaaacttgt ccgagttctg cggtccgttg tatcttgttc gatttcttcg accatcgtat
     9181 tccattttcc gcaatttggg cagcgtccca agaacttagg cgacacatac ccgcaatttt
     9241 ggcaaacaaa ttgtactttt gatttttttg ccattgtacc gcctcctttt atcctaatca
     9301 tgagacatta aatcaagctt aagtatcttt aacgttttat ttactggaag aaccaaatcc
     9361 gccttgacgt tgagcagtcg tttgatcttg atctgctttt aaaaacggca aaaagatccc
     9421 ttggccgata cgctcgcctt ttttgatcac tacatccttg aaaccaaagt tggtgaattg
     9481 gaacatgata tggccttcat ttgcctcatt attgtaataa tcactgtcaa tcacacctac
     9541 tccgtttgtc aacactaaaa accgcttcaa cggattgctt gaacggttag caagctgcaa
     9601 aaattcatct tctcccatgt aagctttgat tccagtaggc acgagggttg gtttcaattg
     9661 tttttcattt tctgatacat cttttttcaa tccatctgcg actgtttcca accccttttt
     9721 ccagcctgct ttccagatac ttggaatcac gacctcttct gctgcttcaa aatcatagcc
     9781 agcagcatga tgtgtagcgc gctgcggtag attgatattt tgatctttat atttagaaat
     9841 aacttcaaat cctctttttc tcaccggttt tcct
//
LOCUS       DAIGWC010000089         9664 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.092, whole genome shotgun sequence.
ACCESSION   DAIGWC010000089 DAIGWC010000000
VERSION     DAIGWC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.092"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..650)
                     /locus_tag="NOB74_002448"
     CDS             complement(<1..650)
                     /locus_tag="NOB74_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI1221591.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIG"
     gene            975..1391
                     /locus_tag="NOB74_002449"
     CDS             975..1391
                     /locus_tag="NOB74_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI1221592.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            1388..1858
                     /locus_tag="NOB74_002450"
     CDS             1388..1858
                     /locus_tag="NOB74_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1221593.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            1872..2645
                     /locus_tag="NOB74_002451"
     CDS             1872..2645
                     /locus_tag="NOB74_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1221594.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            2659..3471
                     /locus_tag="NOB74_002452"
     CDS             2659..3471
                     /locus_tag="NOB74_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI1221595.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3525..4490
                     /locus_tag="NOB74_002453"
     CDS             3525..4490
                     /locus_tag="NOB74_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1221596.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            4606..7329
                     /locus_tag="NOB74_002454"
     CDS             4606..7329
                     /locus_tag="NOB74_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI1221597.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            7342..7974
                     /locus_tag="NOB74_002455"
     CDS             7342..7974
                     /locus_tag="NOB74_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI1221598.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            8873..>9664
                     /locus_tag="NOB74_002456"
     CDS             8873..>9664
                     /locus_tag="NOB74_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1221599.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         3260 a         1477 c         1884 g         3043 t
ORIGIN      
        1 ccaatcatat ggaagccacc gattaggtat tttatgggtt tagtcggaaa tgtttcaaga
       61 gcaatttcca tcatatcgat aatgccatga tgactacagc cagtaaagac aatcagaccg
      121 tcttcttgct caattacgac caataattca tctgaaaaat catcataaac aaatttatca
      181 tccatctttt tgtataaatt cttggtggtc gagtttgctt tgcctagggg gatgatatgg
      241 aagctcggag caagttctgt tttcgttttt attgtatgta aattctcatg cattttaagg
      301 atttcatttt taggaatacc aacatacaga aacgtggtta aaatctttaa ataatggggt
      361 aaagttacac cttcagctgt ataaataggg gcgtttcctg attttaaata tcttaacccg
      421 ccggtgtggt cagaatgacc gtgtgaaata atcactgcct ccagatcatt caaagtttcc
      481 cccattttag tcgcattata gactaatttt ttattagcgc cagcatcgaa gagatatttc
      541 ttccctgagt agttaattaa gagagataac ccatgtccac ttttaaagtt caaatttatt
      601 cttgagtttt caaataaaac cttgatttcc actataacat ctcctttcac atgaacgtgt
      661 attcatatat tgtagcacat taagttctat tttttgttgt aattaccgaa aaaaatatta
      721 atggacgctt tttacgcttt atttcgtatg tggaagaaaa tttcttagga tgtggcgggg
      781 gattggggca aagctaaatt ccaattacag tgatcattta attagacacc tttaaatacc
      841 cacactttca tcaacactat aatttaggga aagaaaagtg ttggcatgat atagaaaaac
      901 ctttaattaa cagcgtttcc taaaattggc acgcatcttg cttatagaaa agcgtaagga
      961 taggaggaat gaaaatggca actataattc ttgccagcca tggggaattt gctcaaggat
     1021 taaagcaaac agctacaatg attattggag atagtgtacc aattcatgcc ttgtcagcat
     1081 ttagagatga agatgaatct attttggtac aaataaaaaa acttttagcc acaatagata
     1141 tagaagaaac ctacatttta actgatattc taggtggtag tgtgaataat gatatgctca
     1201 ctattattaa agagtatgag ggattgcaat taattactgg aatgaactta cctttagtta
     1261 tttctattgc aacctataat ggaaaaattg gggaaagtga gctagaaaag cttattaaag
     1321 agagtcaaca atcagtgatt gattgtagaa aattattagt agaacaactt actggaggag
     1381 atgacctatg attaagttag tacgtattga ccatcgtttg ttgcacggac aggtagtatt
     1441 ttcttggagt aaatcattaa atatcaatcg tattattatt gccaataaag aggcagcgaa
     1501 tgatgaattc aaaaaaatgt ctttgaattt atctaaaccg actggcatta aattaacaat
     1561 tttttcagtt gaacagttac tagaaaaaat gcctaaaatc gaaacactta acgaaaatat
     1621 catgcttatt tttggtaata caaaagaaat tcgtcaattt tgtgaagcct atcctaaagt
     1681 acaagaaatc aactatggag ggataatcaa aaaagaaggt tccaagcaat ttagtaatgc
     1741 cattttcttg aatgaatctg agcaagaaga tgccaaaaaa ttaaaagctc ttggcattaa
     1801 acaatttatt caacaggtac caacttctaa aaaagaagat ttgaatacaa tgttataaag
     1861 gaggaatgaa aatgctcgtt cagtcaattg gtttagggtt aatcggtgtt ttttgtattt
     1921 tagactcaag gcttttagga agaatgaatt ttgaacgacc gttgattgtc agtacgcttg
     1981 ttggtttggt acttggagac atggaaaaag gattaattgt tggagcctct ttggaattga
     2041 tgtccttagg attagtaaat atcggagctg ctgcaccacc tgatatgaat atggcatcaa
     2101 ttattgctac agcctttgcc attttatcaa atgcgaatgc agaagcagca ttaacgattg
     2161 ccattccaat ttcagtgtta ggtcaaatac taggtatctt aatgcggacg attttgtcaa
     2221 atttgactca cgttgcggat cgctttatcg aacaagggaa atttagccaa gcaaggagaa
     2281 ttcatatact ttatggctcg ggattatatg ctctcatgta ttttattcct atttttctag
     2341 caatttattt tggaacgaat cttgtttctc agattgttga tgcgattcct gagtggctaa
     2401 caaatggctt aacggttgca agtaaaattt taccagcata tgggtttgcg ttgttattac
     2461 aaacgatgtt aacgaaaaaa atggtgccat ttttattact tggattttta attactgctt
     2521 attctggatt gggaatcatt ggtattgcag ccttcgcatg tattgttgcg tttgtcatgg
     2581 ttcaagttca aggtaaaaac tcaaatggta accaaaatga gccagatcca ttagatgact
     2641 tataaggagg tagattaagt gaaagagaaa gatcaaaatg catggaaata tcggcagttc
     2701 ttatggcgtt catgggcaat tcaagcctca tggaactatg aacgacaaat gaacatgggt
     2761 tttatgtacg gaattgcacc aattctagat aacatttaca agaatccaga agatgaagca
     2821 atgaagaaag aagcttacga gcggcatatg atgtactaca actgtacccc tcaaacaagt
     2881 gcatttgtgt tagggttaac tgcttctatg gaggagcaat actacgaaga ccaagaaaac
     2941 tttaatccgg aatcaatcag tgcagtgaag acttctctga tgggaccgct atctggtgtt
     3001 ggtgattctt tctttcaagg aacgattcgg gtattagcct ttggactagg aattaattta
     3061 gcccaacaag gtagtatttt aggtccaatt ctagcaatgt taatttcctt tgtaccttcc
     3121 tttttagtta cttactatgg tgggaaaatt ggctataaca tggggaataa atacttgtct
     3181 aaactgtatc aagaaggttt gatggataaa gtaatgtatg tttgctccat tgtggggttg
     3241 atggtcattg gttcgatgat tgccagcatg atcgggatta caacaccaat tcaaatgggt
     3301 aaagcttttg tcttacaaga tgtattagat agtattatgc cacaattttt accattagga
     3361 ttaaccttct tcatgtactg gttattgcag aaaaaggtca aaacaggatg gatgttggca
     3421 atctgtttag tcggaggaat tatttttagt ttgttaggta tcttacaata agggaataac
     3481 caataaattt ggttgaataa tataaataag gaggaattca attgatgaat tcaaaagaaa
     3541 ttgttaaaga aatcgtagcg aaaaaagagg taaaatcaat cgtatttgtt ggctgtggcg
     3601 cttcaaaagc ggacctttat cctgcaaagt attttctaga ccaaaatgcg aagcagttac
     3661 ggattagtca ttacacagcc agcgaattta actatgcaac accagcatct gtagatgagt
     3721 caactgtcgt tatttcagct tctttaggag gtacgactcc agaaacagtt gaagctaacg
     3781 cagtagctaa agaaaaaggt gctacagtta ttagtctaac acgaagcatt gactcaccgt
     3841 taacaaaaga tgcagattat gtaatttatc atcgatttgc agagaactat gctgctaaat
     3901 tagaaaaaac aggctactgt ttagaattgg cagtagaact tttacatcaa gtagaaggtt
     3961 atgaccatta tgaagcaatg caagaaggat ttgctactat ctatgatctt gcccaaaaaa
     4021 gtgcagaatc agctcgtaaa gatgcgaaga aatttgctga acgctttaaa gatgaaaaag
     4081 ttatttatgt aatgagtagt ggtgctacac atgaagtagc atactcaaca tcaatttgct
     4141 tgatgatgga aatgcaatgg attaattctg gtaccttcca ttcaggagaa tttttccacg
     4201 gaccattcga aattgtggat aaagacgtac cgtttatatt attaatgaat gatggaaaaa
     4261 ctagaaatat agatgctcga gcattaactt tccttgaacg ctttgatacg aaaacagaag
     4321 ttgtagatgc cttggattat ggcttgtctt cacatattgc taaagaagtc ttagactact
     4381 ttaacccatt cgtgattact gcagtattta gagtttatgc agaagaattg tcagaagcaa
     4441 gagaacatcc attaactaag agacgttata tgtggaaact aacttattaa aaaatagatc
     4501 aaactaaata aggtggcttg agaaattaag ccaccttgtt ttcttcaatg tgattttata
     4561 catatggtaa aataactagt acatattgtg aaagcaggtg gcaagatgca gcgattaaat
     4621 gactatcttt atcaactaac attgcttttg aaatctacgc cttcagataa ttattcagct
     4681 cgcagtattt cgcaagcttt acagttgaat agaagtacaa tcagtagcta cttaaatgaa
     4741 ggtgttcgtg aagggctttt cataaaagta aaaagttacc cggttttatt tttacataga
     4801 acagctcttg aagaactaca tatcacactg aataactccg aaatagaatc aattgaaagc
     4861 ttgttaacaa tttctcaaaa acccgcatta gatcaagtaa ttggctctaa aggaagtttg
     4921 aaagaagcaa ttgatcaaat taaaacggca gtcttatatc ctggaaaagg gttgccttta
     4981 ttattgatcg gcgctagtgg atcagggaaa acctttctag cgaataaaat atatgaatat
     5041 gcagtagaag aaaaggtcat tcacacatcg gcacctttca tagattataa ttgtgcacaa
     5101 tatgtgagca atccagagtt actatcctct gctttatttg gctacacgaa aggagcattt
     5161 accggagcaa gccaggagca tactggtttg ctagaaaaag ccgatggagg agtattgttt
     5221 ttagatgaag tgcatcgctt atctgaagaa gggcaagaga aattatttac atttatggat
     5281 acgggtgaat tctctcctat gggggataat agtattcgga aaaaagccga tgttcgatta
     5341 gtctttgcaa caacagaaaa tatatatacg actttcttac caacttttct taggagattg
     5401 ccagttattg ttaatctacc tagatttcaa caacgtccgt cgtttgaacg tctgtcattg
     5461 attgatgaat tttttgtttc tgagagtaaa attttagcta aggaactatc tgtttctgat
     5521 gcattgattc atttcttaat gaatagtgat tttgaaggta acgtggggaa tattaaaaat
     5581 attatcaagt atgcttgcgg aaacgcatat atccaccaga agagtcagca aacaattcaa
     5641 gttaaattat tggatatgcc tttagagtac agttataaat tcaaggagca actaaataaa
     5701 cccagaaaga aaagagcaga tcgaatctac tatccagaag aaacacgaca agtgcaacta
     5761 gaaagaaaca atcagctttt tgttcaattt tttgaccaat tacttactgg attctctgaa
     5821 gtgattgaaa ataacaagga tattaaacta tttttagaag aaatggttac caaggtaaca
     5881 caagtaatgg atacgcttat ttttcaagag gattacgaaa aagagcagtc tttatacgcc
     5941 attctaaact atcatattcg tcaaagtatt gattttatgc gagaaagcta cgggtttgaa
     6001 caagatggta accgggtagt cgctttggcc aactatctat atgtcaagga taatcaagtg
     6061 atttttgaaa atagtcttca agaaaagaaa accaaagatc agcttaacga attttttgct
     6121 aatgttcttg aaacccctta ttggtatgca aaaaaaatct taagcctttt atctgagtgt
     6181 ttagatcaac ctgtgtatga agaggacatt ttctttatta cgctatattt ttatagtttg
     6241 aatgtcacga atgttaaaac aggtattaag agtattgtgc tagctcatgg ttattctaca
     6301 gctagtagta tggcgaatgt tgccaaccgt atgctgaata agaacgtttt tcaagcttat
     6361 gatatgcctt tagatattac attagagaaa attgaagcaa aattgattca attccttgga
     6421 gattatcgaa cagattcagg cttgatttta ttggtagata tgggttcact aaaccaacta
     6481 ggcggtttat tagtgaatca tctaaatgga ccactgttaa tcattgatca tatcaataca
     6541 ccgttattat tggaagtcgg ccaacaagta ttaaacaata aaagtatcac cgaaatagga
     6601 gcagaaattg aaacaagtct tactttcaaa aagcagttac tacttcccaa gaaaaagaaa
     6661 aagaaagcca tcattacttg ttgttataca gggattggta gtgcgaccca gattcaggag
     6721 attttaacga aatgcttgaa agatgcagtt agagaattag taattattcc gtatgattac
     6781 aaaaagctgt tagaaaacaa gaattttgag actccttttc aattatacga tgtcatcatg
     6841 attgtaggta cagaagatcc caaaattaat cagattccat atattggatt agatcgcctg
     6901 attaatgggg aagcaattgg cgaatttgtt cattacttgg aaaaagagct gactattgaa
     6961 gtgaacgatt tacaaaaaga attaattttc aatttttcaa ttagtaaaat tgtcgaaaat
     7021 ttaaccattt tggatccaga taaggtgcta tcttttgtac aaaaagcaat taaagaatta
     7081 tcgaagttat taaattttga tttttctaat aatcagctgt ttttgttgta ccttcactgt
     7141 agttgtatga ttgaacgaat tgtacgtaaa gaaagtgtgg atgagcaaga ggacattgaa
     7201 gaatatatgc aagcaaatgg agaaataatg gataaaattc atagcgcttt ttttgagatt
     7261 gaaagggaat acacaattga aataccagat ttagagttgc gattattgag cgatattgtt
     7321 caaggatagg agtgaattcg aatgacaatg ggagtaattt ttgatatgga tggggtactc
     7381 atagacagcg agacatttta ttttgagaga agaatgaact tctttcaaga actggagata
     7441 gatccaggat caaaccagat tgatgattat gtggggaaaa cagaagctgc aatatgggaa
     7501 acattagttc ctgaggacaa atcattaaga gaggaacttt atccgaaata tgtagattat
     7561 cgaaaaacgc atccaattga tttcgctaaa gatttacgaa aagaagtgaa accgttactt
     7621 gacttcctca agaagcggga tataccattg gcactggcat cttcttctcc agttgttgag
     7681 atagagagta tgctcattca atgtgaactt actgaatatt tttcctttgt tataagtggt
     7741 gagtcattaa aacaaagcaa accacatccc gaaatatatt taaaagcgaa acagcaatta
     7801 gactgtgact tctttattgc agtagaggat tcaacgattg gtattaaatc agcaaaggca
     7861 gcaaatatct atacggtggc actaaaacaa ccaatgcaaa tcgatcagag tgaagcagac
     7921 atacaaattg aaagtctaca agaactggaa caaattgttt tagaaaaagg ttagtgaatt
     7981 aatggaaata aggctatata tctgtgctag ctattttgac taaccaaaaa aacttgctat
     8041 aattcaggtg tagtaaaagg tgctggtaac accttttacg aaaatgcttc ggcagtgata
     8101 atgggattgg ctttttaagt tttttatttt gttcgcaatc cctaaggtca tgtgaatgat
     8161 cctagggatt gctagaatat tttgcaacat tctatctatt tcagaacgta accttcccca
     8221 gttcattggg attcattagc atacaaccaa catttcaaaa agaaattgca ctacaccatt
     8281 attagctatt ttgactaacc ccaaaaaact tgctataatt caggtgtagg taaaaggtgc
     8341 tggtatcacc ttttacgaaa ctgcttcggc agtggtaatg agtgtggctt aaaggactag
     8401 tcctttaagc tttttacttt gttcgcaatc tctaagatca agttaatgat cgataagatt
     8461 gctagaatat tttgcaacat tctatttcag aacgtaacct ttcccattcc actgtgattc
     8521 attggcaacc ctcctcacaa ccaacgtttc aaaagaaatt gtaaagttgt tggggtacca
     8581 cgaccgaaca atactacacc tgaatgatag taagttgtct cattaagtat agcatatcct
     8641 ctttttgggt aaatagaaat cggttacatt ttttatccaa gaccaagttt tttcatttgg
     8701 tcttatttgc tatacccaaa caattccgca gtatagtcga cggtattgat tttatcaggt
     8761 gagtaataga aacttgtttt ccttccccaa aacattacct ataaaggaga aaaaatggta
     8821 tcgtaattat ataggtatag gatgaaattt ttttctaaga ggagggttgt tgatgaaaaa
     8881 tttacagtta aaatttattg ttgatccatc gattgtacgc tggtttcgga ttatcaatca
     8941 atttgagcgc aatcaacttg ccacaaaagg agaattagca aagagtaatc atgtatctga
     9001 acgaaccatt caaacagatg tcaataaaat gaaggactac ttttctgaaa gtgttcaatt
     9061 tgtttcaacg aaaagtgggt attcttttca gaaggaaaga ccggttcttt ttctcaagca
     9121 gaaggagcaa ctactggaga acgaaatttt atttgagttg ttagggaatg tcttttatgg
     9181 cgaattggaa gatatgacgg agctaattga tcgttttcat ttatctgaag cgacttttcg
     9241 tcggtatttg aagcagattc aaccagtttt ggaagaatac ggcttagaat tgagtcttta
     9301 tcctcttgat ttaaaaggag aagaggcaaa tattcgcaag ttttttaaag acttctatta
     9361 tgaaggggag atgacgcccc atactcttgt tccaccaagg gatcttcatg aacttgtgca
     9421 agctacattc tatgataaat ttgagtattt ctcgattgga acagggactt ctcctgctga
     9481 attttattat agtttgtata ttgcgattga gcgtgtgaga caaggaaaaa cgatagccat
     9541 tcctcaaggt ctgattgagc gagtaattgc tagtgagaat tttcgcttaa tgtattcctt
     9601 gaaagaagcg attcaaacaa attatcaagt tgctttatca gaagaggagt tttgttggtt
     9661 gtat
//
LOCUS       DAIGWC010000090         9591 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.093, whole genome shotgun sequence.
ACCESSION   DAIGWC010000090 DAIGWC010000000
VERSION     DAIGWC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.093"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..643)
                     /locus_tag="NOB74_002457"
     CDS             complement(<1..643)
                     /locus_tag="NOB74_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HCI1221600.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTK"
     gene            complement(645..1409)
                     /locus_tag="NOB74_002458"
     CDS             complement(645..1409)
                     /locus_tag="NOB74_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HCI1221601.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(1417..2094)
                     /locus_tag="NOB74_002459"
     CDS             complement(1417..2094)
                     /locus_tag="NOB74_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HCI1221602.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(2131..3516)
                     /locus_tag="NOB74_002460"
     CDS             complement(2131..3516)
                     /locus_tag="NOB74_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI1221603.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(3726..3810)
                     /gene="ffs"
                     /locus_tag="NOB74_002461"
     ncRNA           complement(3726..3810)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="NOB74_002461"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3833..4348)
                     /gene="tadA"
                     /locus_tag="NOB74_002462"
     CDS             complement(3833..4348)
                     /gene="tadA"
                     /locus_tag="NOB74_002462"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HCI1221604.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            4455..5312
                     /locus_tag="NOB74_002463"
     CDS             4455..5312
                     /locus_tag="NOB74_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1221605.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(5393..5728)
                     /locus_tag="NOB74_002464"
     CDS             complement(5393..5728)
                     /locus_tag="NOB74_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221606.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(5795..7165)
                     /locus_tag="NOB74_002465"
     CDS             complement(5795..7165)
                     /locus_tag="NOB74_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HCI1221607.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(7243..7779)
                     /locus_tag="NOB74_002466"
     CDS             complement(7243..7779)
                     /locus_tag="NOB74_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1221608.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            8088..9569
                     /locus_tag="NOB74_002467"
     CDS             8088..9569
                     /locus_tag="NOB74_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1221609.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         2907 a         1969 c         1502 g         3213 t
ORIGIN      
        1 tttttgtttg tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta
       61 ataatacaaa aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga
      121 ttggatcagt aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa
      181 ggataaaaaa gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca
      241 tgccgatttg aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga
      301 taaacaaaat actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa
      361 ttttcacttc ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga
      421 ggatggtttt gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg
      481 tctcttgatc taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata
      541 gtggtcgaaa gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga
      601 acaatccagc atattccatc cactgccatc tcgaattttt catattagaa gctccattca
      661 tccagtgatt gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt
      721 gtaaaacctg ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct
      781 gtttcatagt tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg
      841 gctttatcca taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct
      901 gtctctacaa aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata
      961 ttcttatctg ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta
     1021 actacttttt cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct
     1081 tcttcccatg taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca
     1141 tagacttttt tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg
     1201 tagactgtct ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt
     1261 tctggtgact tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat
     1321 tcttccacaa atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct
     1381 aaatcaatta aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt
     1441 aaatgctgtt tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga
     1501 ggtttttgct gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac
     1561 tggtcctttt ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg
     1621 agttgtcttt tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt
     1681 gcaatattcg taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg
     1741 attatccgct tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat
     1801 ataatcatat cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc
     1861 ttcacgataa tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc
     1921 taacagtgtc actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc
     1981 caaagcagct gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt
     2041 agcaatttct gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc
     2101 accacctatc ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta
     2161 atctcctacc acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc
     2221 aatcgttgga aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt
     2281 attcagatcg attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat
     2341 tccattatag accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata
     2401 gttacgtaaa aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc
     2461 acccaatgtg acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg
     2521 attgacccgc ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc
     2581 cgtctttcct cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa
     2641 gatatctaga ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg
     2701 cccacgttct agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc
     2761 ggtagggatg gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg
     2821 gacttcaccg acatactgcc cgtactttcc agcggctgct atttggacat cattgattac
     2881 gtgaccttct ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat
     2941 ttcttttgca atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc
     3001 cacttgtgaa cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc
     3061 ccagccattc ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt
     3121 cgtctggtgt ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt
     3181 atttttatcg aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt
     3241 caactcttct ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc
     3301 aacttcattc atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca
     3361 acgatccaca aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt
     3421 ttctcgttta cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg
     3481 cagatcattc gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct
     3541 ttatcatacc ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc
     3601 tgccttgaag caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag
     3661 gaacattcat ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg
     3721 tttcattata atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac
     3781 acgcttcaca agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt
     3841 cattcgttga ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt
     3901 cagtcaaaat catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt
     3961 taaaccgctc gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat
     4021 acgcgccgaa ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac
     4081 aaggctctaa ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac
     4141 aggcttcctt gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa
     4201 ggttatatcc tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt
     4261 catgaagcat ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt
     4321 ctactgcatc aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt
     4381 tactttagca tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac
     4441 aagaggtgaa caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa
     4501 aaaactctcc agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct
     4561 ggatcaaaca agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg
     4621 taatcaacga tcaaaaaaaa cacccatggt atcgctatct ttttaaagat gcttcttgtg
     4681 ttcaagaaaa aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa
     4741 aaaaagaatg gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt
     4801 atacagacac agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg
     4861 aaatcaacgg tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg
     4921 ttggttcttt ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa
     4981 tttttttaac agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg
     5041 tggctttaca ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca
     5101 tagaactgat caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag
     5161 gcaatgtcag ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa
     5221 tcgaaaaatt tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt
     5281 gctatctttt attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa
     5341 ttttgtcaca accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca
     5401 ttttttcaac aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat
     5461 caccataaac agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag
     5521 aatccaagtc actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa
     5581 atttgtcata gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca
     5641 ttacttttcc cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc
     5701 cgattgttac ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca
     5761 tagcatagac aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga
     5821 aaaagttctt tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata
     5881 ctagcaaaac ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt
     5941 gccattcctt ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg
     6001 ctaatgcata gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac
     6061 gtacgacttt taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt
     6121 tgaacactaa aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga
     6181 gtttttcctg ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat
     6241 gcatctgatt ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt
     6301 tatgaggcca tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc
     6361 ctgaactaac ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa
     6421 gccagctaat gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt
     6481 gtcctttatt ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac
     6541 agtatagcgg agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc
     6601 cttctcctga acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga
     6661 caagttctgc gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat
     6721 tttctgataa aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc
     6781 ccttcatttg agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa
     6841 ctttttcacc gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc
     6901 tatattcata cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct
     6961 cattgctgta gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc
     7021 ctgccggttt tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag
     7081 aaaaaaaatc ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg
     7141 gtaacgttgt cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt
     7201 acgaaaaata aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt
     7261 taagatattt tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat
     7321 ttcaagaaaa tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac
     7381 caattcaagc gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg
     7441 ccgcttaaat agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc
     7501 atggatagaa aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca
     7561 ttcagctaag tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc
     7621 gctgattgat ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa
     7681 ctctcttgca gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag
     7741 caaatattct ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca
     7801 tctacccata aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca
     7861 tatttagtta tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca
     7921 aaatacccta ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta
     7981 tataaaaaag aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac
     8041 agtttttgtc taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag
     8101 caagaaaaaa agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac
     8161 aagaattatc caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa
     8221 taaatgtatc actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag
     8281 gagagatcca aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa
     8341 aattatgcta cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc
     8401 cacaaactgc tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc
     8461 tcgaaaaact gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat
     8521 ctgtaaaaaa ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact
     8581 tttttctttc agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg
     8641 cactaaaaat gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata
     8701 tctacttgct gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa
     8761 cttcttctga aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat
     8821 actttacttc tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact
     8881 ttaattattt tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga
     8941 ttggtttttt attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga
     9001 cttacttaac tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt
     9061 attttcttgt gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt
     9121 ctacactttg ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga
     9181 aattaagaga aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc
     9241 aataccttag tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca
     9301 tccatttgca gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc
     9361 agttatttcg caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca
     9421 ttacagatca gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc
     9481 acaatacagt gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag
     9541 gttatgagaa caaaacaaag aggatgtgac aaaattcttg tcacatcctc t
//
LOCUS       DAIGWC010000091         9442 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.094, whole genome shotgun sequence.
ACCESSION   DAIGWC010000091 DAIGWC010000000
VERSION     DAIGWC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.094"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            59..205
                     /locus_tag="NOB74_002468"
                     /pseudo
     CDS             59..205
                     /locus_tag="NOB74_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            282..611
                     /locus_tag="NOB74_002469"
     CDS             282..611
                     /locus_tag="NOB74_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI1221610.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            601..888
                     /locus_tag="NOB74_002470"
     CDS             601..888
                     /locus_tag="NOB74_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI1221611.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1174..2031
                     /locus_tag="NOB74_002471"
     CDS             1174..2031
                     /locus_tag="NOB74_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI1221612.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYVEVE"
     gene            2032..2580
                     /locus_tag="NOB74_002472"
     CDS             2032..2580
                     /locus_tag="NOB74_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221613.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            2840..3473
                     /locus_tag="NOB74_002473"
                     /pseudo
     CDS             2840..3473
                     /locus_tag="NOB74_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(3518..4467)
                     /locus_tag="NOB74_002474"
                     /pseudo
     CDS             complement(3518..4467)
                     /locus_tag="NOB74_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            5069..6913
                     /locus_tag="NOB74_002475"
     CDS             5069..6913
                     /locus_tag="NOB74_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1221614.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            6969..8435
                     /locus_tag="NOB74_002476"
     CDS             6969..8435
                     /locus_tag="NOB74_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1221615.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            8472..9314
                     /locus_tag="NOB74_002477"
     CDS             8472..9314
                     /locus_tag="NOB74_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1221616.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         3246 a         1442 c         1906 g         2848 t
ORIGIN      
        1 agcttaaatc atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac
       61 ccaatcattt gagaagttaa aacctacaca tgaaggtagg tattttagaa gattgaatag
      121 acaacaccgg gttgtttata aggtagatga agatgaacac gtggttgaaa tttattcagc
      181 aaggacgcat tacgagtcac agtaattact tgtaaataca ttatctcgtg gtataatgta
      241 tttactaagt aattacatac tgttagaaat gagggattta aatgattaca aaaacaagaa
      301 aacaaggcaa ttcaatcatg ttgacagtac ctaaagattt taatgttcct aatggagtcg
      361 aagttgaagc aaagttggta gagaatggta ttctttatga atttgttgaa ccacaaaaag
      421 aattttatga ttttagcgaa gatattttgt ctgatataat tgcagaaggc tacgataaag
      481 atgagattct tgtagaattt aagaatagaa aaaacaaaat gcattcttcc tttagagata
      541 ttgctgaaga tacacttact aattctaaag taatgactaa agaggagttg gcaacagaaa
      601 ttggcttatg aaatcgttcc ttcaaaacat gtcattaagt atttaaaaaa gctaaaagag
      661 aagccattga aagaaaaatt tttgaattta atttatgatg aaattgcgat tgatccatat
      721 aagggtgaac aaaaaactgg ggatttatca ggtatttggt ctagtgggtt caaatatgcg
      781 ggcacaacat atagagtagc ttacgagatt atagaaaaca aggttattcc agtattgtta
      841 tgtggaacgc atgaaaactt ttatgaacag ttgaaaaaat taatctagtg atttgttgtc
      901 gttcttaaga aggacggctt cttttttatc gaaaatctga ttcgtctaca tgactaaagt
      961 cgcgagtatt ctctgcttct cgataaatta aataacgtca ttactttgag gaaagctata
     1021 aatcaatata tttcagcttt tccttattta tgtactacct tttacttatt aattataagg
     1081 tagtacatat atatcttttt tttggtagta actaaaaata aatatgttat aatagtatca
     1141 aatgaatatt gctaaaagaa aagaggtagg aacgtggtag cgaagaaata tgtaatcggt
     1201 aattttaaag gtggcgtagg taaaagtacg tgcgcgcaaa tgttagggtt tgaatcagca
     1261 gttaatgaag gaaaaagaac cttgataatt gacttggata tgcaaggaaa tacttctgat
     1321 gtgatgaact taacgcatat gaacttcact aacgaagaag gaggcggaga aggtgaaccg
     1381 attgtttacg aaaatactgt gactgacgtg ttgataaaca atcttccacc taaagaggct
     1441 gtctataaag taatcaataa cctctatata cttccagcag acatgtcctt tgaaatgtat
     1501 gatgattgga tcaaagacca atataatgat tcattatccc aattcaaata tatgaaagaa
     1561 aagctagaac cattatttga tgagtttgac gtcatctatt tagatgtccc accttctatt
     1621 tctgtatata gtaaatccgc gatgtacatt gcggattggg caatcgtcgt cttacagacc
     1681 caagtaaaat cgatgagaaa tgcgatgcaa tatcttgagt atatggactt ttttgtgaaa
     1741 gaatttgata caaatttata tgttgctggt gttattcctt tcatgttgga aagcggtgac
     1801 gcagtagatc aggaaatgta taaacaagcc caagagattt atggggaaca tttgattaaa
     1861 aatgttgtac tcaaaaatgc gcgcttaaaa cgatacgacg gatcaggtat tacgatggag
     1921 aagacaaaga aaggtctctt aaaacaatgg gatcgcaaaa gccacgaatt atttatcagt
     1981 attttgaaag aattggaaga acacgagaat tggtatgtgg aggtggagta attggctgac
     2041 atcaaaggac ttgatatttt tgggaacaac aaaggactcg ccaaaataaa aaaagaagca
     2101 gaagcaaaga aaaagcagca agcaattaca ccatctgaaa ataagcaatt agaagtgcac
     2161 caagttcaag aaataaaaac ttcctccaat gttgaaagac agagtagagg aagaacaaaa
     2221 aaagttggcg caccaatcag aaagtttgat aaggtttatt ccaccaagca tcctttaaaa
     2281 ctgtcgactt tgttaaatgc gacttccaga gttttagtag aaaagtatga gactaatatg
     2341 acaagagatg aattgcttag aaaagcttta gatgagtata ttaaacagaa tcttacgcaa
     2401 gaagataaac aagatttgtt taatgacgtg gtgaaagaac tagacttgtt cagagaaaaa
     2461 tatccaattg ttccagaatt agatgatcgt ggagaaataa taagaactac cagtcagata
     2521 aaacaagata ccgaagactc actgcgcaaa gggtggggaa tgaataataa agttagataa
     2581 taatcaaaga agaactaagt aactaccttt aaacggtagt tacttagttc ttctttgatt
     2641 tgcgtgaaat agaggggatt tatttttctg gttacgtgat taaaaaatcc aaaaaatgag
     2701 cataggaacg gttatgattt tagggtgtgt tttaatgaga tattgtgatt tcattaataa
     2761 gtgtatgata atctgttgtt gagttagtaa ataagtaata gagctaactc taaaataaaa
     2821 ctattaggag gagatgtaga tgaaaaagtt taaaaagaaa atatatttag gattggttgt
     2881 tggggtgagt atgtttgggt tcatggctca tactaaacaa gtaactgcag atactaacca
     2941 aaaagaaagg attatgagcc aattagatga ctctcaaata gagtatgtac ccaatgagct
     3001 aattgtcagt ttaaaggcta cacaaagaat ttcaacagag aaaaataaac cgcaaaattt
     3061 attgggtgta aaagttatgg tggaaaaaga tttgactctt aggacaaatg aaagcgatta
     3121 taataagcga gatcaagtat tattagtgaa attgaacgaa gaaattagtg tggaagaggc
     3181 agtaagaaca tttaatgctt ctgatatggt caattatgca gagccaaact atgtggttga
     3241 actagagccg ttgaatgatg ttgaggagcc aaatacaact gattctttag gaaatcgata
     3301 acgatcctaa ttggagtaaa caagctaatt taagagagat tagcatgcca tccgcttggg
     3361 aagaaaccaa gggttctaag gatgtgaagg tagcggtcat tgattcagga attgattatc
     3421 aacatgaaga tctttctgga aatgtagatg aaagtttggg atacgatttt ttttactttt
     3481 ttcaagaaaa taataattca gaatattctg actatattta tgcaacacta gtgactttag
     3541 gagaaacatc aatagccttg ctaaagtttt tgctttcgct aaagagagta ttttcgataa
     3601 tttgtttttt tctaaaatac ctcgttcctc aatatttggg atatggatat gtatagggat
     3661 tcttcgcata aaggtttcca gaaaatcctc tttgccttct gtagtcgcaa aaactaaacg
     3721 tacattggag gcgtgatgga tagtttcacc gactctagaa taagttccgc catccatata
     3781 aacaaatagt ttctcttgcc cttcaggagg caatctgtgt acttcgtcta aaaacagtac
     3841 tccaccgtct gcatcttgca acaatccatt tcgatcttca tctgcgccgg taaaagcacc
     3901 tttaacatag ccaaatagta tccccgacaa taattcagga ttattatggt attgcgcaca
     3961 attaagtact ttaaaaggag cattctcatg aataacgttc acttttttca taaactgata
     4021 agcagtatga acaaaaaaac tttttccaac tccagtatct ccagtgatca tcataggaag
     4081 ccctcttcca ggatagaaga cagcagtttt catttgttcc accgcatcgg ataagctcat
     4141 atcataccca atcatctttt gtagaatgga atctgtagaa ttgggctcca agtctgtttt
     4201 taattcagat atactttcgt atacatcttt taccggaatc aaaaagtgct cttcaaagcg
     4261 ctctttgatg gcaaataaca ctggacgagt attgatttta aatagaacgt tctttgcaac
     4321 taagtcattg gcaagtttac tggcatttgt tcttcccgtt cttaaaaatt gcgacaggtc
     4381 atttgtgtca aaaaagcact cttctaaatt actgatgcca atttcttcac attttgtgtt
     4441 tgcataagtc actatatcat ttttcatctt ataaacagtc ctttctaaac ttctatccct
     4501 taaataaata gcaaaaaaaa ggaagcaata tcgatatgct gtcctcttaa tttaataaag
     4561 cgctaatcta attcactgta ttatcatttt ttagtagtat agcacaatta tgaatgcctt
     4621 ttctttatat caaataaagt ttatataaaa aacctcatcc tgcaagaaag aaaaaatgaa
     4681 cccattcttt ttatactagg tcttaaaaag acagaacatc tgctagaaga tagaagagaa
     4741 taagagttat atatgttgga agatattctt agaaaaaaga caaaactttt agaacacgaa
     4801 aactatattg aacgaataaa atgaaaaaat gattaaaaaa tcattttatt atttacgttt
     4861 acattctaat atgttaaatt gaatataact taaacaggca tgtgactggt aatgcaggca
     4921 ggacctaaat aagttgaata acaatgtatg cgtttcaata cacgtttgcc ttgttgtcaa
     4981 tttatttagt ttctgcctgt tttttgtgtt gaggatggcc acttcgactc aaaagttcat
     5041 cactcaaaaa agaaaagagg gaaacaccat gaattacaaa caaacagcag aagaagtatt
     5101 gcagtacatc ggtggggaag aaaacatatc ccatttggag cattgctcaa ctcgtttacg
     5161 ttttacgtta aaagacaaca gcaaggtaaa tatgagccag ttagaaaaag tggatggcgt
     5221 tatgggcgtt cgccaaaatg tgcaatgcca agtaatcatt ggaaacgatg ttgttgaagt
     5281 gtatgatgaa gtgaaagcgt tattaggtga caatgtttca aatactgaag aagcaccaaa
     5341 acaaaaacaa aaattaggtt cagttctatt agattttatt atttctattt tccaaccttt
     5401 aattcctgcg attgcaggtg gaggagtatt gaagtccttg ttgctactag cttctatctt
     5461 agggctgatt agtgaccaat ctcaaaccta tcagatttta aatttggtcg gcggggcacc
     5521 gctttatttc ttgcctattc tggtggcaat gactacggct aataaattga aagtcaatca
     5581 attggttgca gtatctgctg tcggtgcatt gatccttcct gaaatgacag ctatgttggc
     5641 ggaaggtgct acattcttat cttttggatt ggataatata gcgtatgcat ctcaagtatt
     5701 cccagccatc ttaactgttt tattttatgc tcaacttgaa aaatggttta caaaagtttc
     5761 accaaaacca attcgtattt tctttgtacc tatgatgagc ttattgatta cagttcctat
     5821 tgctttgttg cttctaggac cattaggtta taatgtagga acagctttct cttctatcat
     5881 tgtgtctttg tacaatcaat ttggatgggt tgcaaccgga gtcttagcag ctgtactgcc
     5941 attaatggtt gtaacgggta tgcataaagc aatgatccct tacgctgttt catccatgag
     6001 tgaattgggt gcagaacttc tttatctccc ggcttcattg gcacacaata tttcagaagc
     6061 tggcgcatgc tttgctgtca gtatcaaaac aaaagacaaa aaattgaaat ctacggctgt
     6121 ttctgcgggt atatctgcat tattcggaat tactgaacca gctctttacg gggtaacgat
     6181 tctgcacaaa cgtgttttat atgccgttat gttttctagc ctgatcgggg gagcatttgc
     6241 aggaatcgtt gcacttcaag cctttgcttt agtgggtcct gggattgcaa gtatcacgat
     6301 gttcgctgac aaagctgacc caatgaatct ggtttgggca tttgcagtat cggggatttc
     6361 atttgtggtt gcttttgctg cagcgttggt tctttataaa gataaagaag ttgtcaatga
     6421 agttgaaact aagatggaaa cggccgttgt ttcagatgct gttctttcaa gtcccgtgaa
     6481 tggaaaagta atctcactat cagaagtaaa agacactgtt ttttctagtg gtatggtagg
     6541 tgatggagta gcaatcattc ctgaagaagg gatattagta gctcctgaag atggagaaat
     6601 cacaatggta tttgaaacga agcatgctat tggtttaaaa acggctaatg gtgcagaact
     6661 tctttttcat attggtattg atactgttca gttagaagga aaagggtttg aggcatttgt
     6721 tcgttctggt gaaaaagtag ccaaaggaca aaagctgatt gcatttgata ttgatttaat
     6781 caaagaagca ggattcgacc ccacagttat ctgtgtggta accaataagg ataattacac
     6841 tatccgttca tttaacctag aaaaattggt aaccaatgat agtgatctct tagctatcag
     6901 tccgatagct taaacacaag atagtgaaaa aaaatatatt gaatgaagga atagaggaga
     6961 atagaataat gacaaacaca acaagttttc caaaaggatt tttatggggc ggcgcgatag
     7021 cagcaaatca agtagaaggt gcttggaatg tagacggtaa aggtctttca gtagcggata
     7081 tggctactta taaaccaaat ttagacaaca aagattttgc tgctcatatg catgtcaccc
     7141 tgcagtctat aaaagaagct agtgaagaca aatctgataa atggtaccca aaaagaaggg
     7201 gcgttgattt ttatcatcac tataaagaag atttagcttt atttgccgaa atgggcttta
     7261 aaaccttgcg cctctctatt gcttggactc gcttgttccc tacaggagaa gagctggaac
     7321 cgaatgaaaa aggggttgca ttttatgaaa acgtctttaa agaaatgcaa cgtttaggaa
     7381 ttgagccgat tgtgacacta tctcattatg aaatgccatt agctttagca gttaaatata
     7441 atggctgggt ggagcgtcga gtaattgatg attttgttcg cttcgctaac gtttgttttg
     7501 atcgcttcgg caaatacgta aaatattggc tgacatttaa tgagatagac agcatccacc
     7561 gtcatccatt tacaacagct ggaattatcc aagagaaaag cgcagaaggt caagaagctc
     7621 aagatatcta tcaagcattg catcatcaat ttgttgcgag tgcgttagtg acaaaagatg
     7681 ctcatgaaaa aattccagga agccaagttg gttgtatgtt aacgaaattg atgacttatc
     7741 cattaacttg cgcaccagaa gacgttgagc tgaccttgaa aaagaactta gaaaataatt
     7801 tttatgcaga tgttcaagtt aagggagaat atcctgctct aatcgaaaag gatttggaaa
     7861 atcggggaat tcagattaaa atggaagatg aagatcgaga aattttaaag aaacataccg
     7921 tagattttgt ttctttcagc tattacatgt ccatggcaga atcagctgat ccaaacgcag
     7981 aacgcacacc gggaaatact gttttagggg ttaagaatcc tcatttgcct tcaacagatt
     8041 ggggctggca aatcgatcca aaaggtttga aaatttcgtt gatcgaactt tatgatcgtt
     8101 accaagtacc gttgatgatt gtggaaaatg gtatgggagc agtcgatcag gtagtagatg
     8161 gtaaaatcca tgatccgtac cgcatcgact actttaaagc acacttccaa caaatgaaag
     8221 aagcaatcga tgaaggtgta gatttgatag cttatactag ctggggacca attgatttag
     8281 ttagtgcagg aacttctcaa atgtctaaac gatatggatt tatttatgtg gatgcagacg
     8341 atgaaggaaa tgggacatat aaccgcttga aaaaggattc gttcaactgg tacaaagaag
     8401 tgatcgaaac aaacggtgca tccttattcg agtagtctcg atctttttaa gcagcgatag
     8461 ggggataatg agtgatttca ataaaaaaag tattgaattc aagtgtggta cttgttgaag
     8521 aaaatggcaa agaaatgatt gcattaggta aagggatagg ctttggacag aaagctgggg
     8581 atgaaatatc aggagataaa gtagataaaa tatttctgcc ttttgaagaa aagaaatctt
     8641 cacaactatt agagttagtt gaagaaatac ctattgaatt ttttgaaatc actcgtacta
     8701 tcgtttttga agcagaaaaa ggattagata aaaaactgaa tcctggagtc tatttaacct
     8761 taacagacca cctgcatttt gcagttgaac gcgcacaaaa aggggtaaat attgcaaacc
     8821 gtttgtactg ggaaataaaa atctactatc ccaaagaatt tcaaattggg aagtacgcac
     8881 tcaccctttt gaacgagcaa tatggaattg atcttcctaa agaggaagcc tcaaacattg
     8941 ctttccattt gatcaatgca caatcggaag atcctgatag cggcgctgga ttcaagtatg
     9001 caaaaatgat cggcgggatc gtcaatttgg tccggtattc gttgcagaaa gatatcgata
     9061 ctaattcgat ccattatgcc cgcttcatta cacatgtacg tttctttgta gaaagatatt
     9121 attctgatgc tttgttggat gatggtgagg aagaattcta caatcaaatg tggatcttat
     9181 acccgtctgc catggaaagc gcagctaaga tcaaagacta cattgaaaaa gtttatcata
     9241 aaacaattcc gaacgatgaa gttgtatacc taggtgtcca catcaatcgg ttgatgaaac
     9301 atgctaatgg gtgagcgctc agtaatacta ttgatgcttt taaaatcttt agagatggat
     9361 tatagtaaaa acaaggtgat ttccagctgt ttgttatcta taagagacat ttaaaaagga
     9421 ttaacgtaag ataataaaaa at
//
LOCUS       DAIGWC010000092         9432 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.095, whole genome shotgun sequence.
ACCESSION   DAIGWC010000092 DAIGWC010000000
VERSION     DAIGWC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.095"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..680
                     /locus_tag="NOB74_002478"
     CDS             <1..680
                     /locus_tag="NOB74_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1221617.1"
                     /translation="YFSRFSLATREAVQWIVIDMYAPYVSLVKKLFPNAQLIIDRFHI
                     VQHIGRTFLNHRVKETTARLKGTSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRAS
                     FKDYLTESEIVDRLLSACPNLRQGYQLYQDILYAVKKRDQSLFEDCLNREVSGLPETY
                     TTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRSFYNFKLRIMIRH
                     GKTFLTK"
     gene            800..1000
                     /locus_tag="NOB74_002479"
     CDS             800..1000
                     /locus_tag="NOB74_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI1221618.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            1076..1273
                     /locus_tag="NOB74_002480"
     CDS             1076..1273
                     /locus_tag="NOB74_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221619.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(1570..3117)
                     /locus_tag="NOB74_002481"
     CDS             complement(1570..3117)
                     /locus_tag="NOB74_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HCI1221620.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(3201..4004)
                     /locus_tag="NOB74_002482"
     CDS             complement(3201..4004)
                     /locus_tag="NOB74_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI1221621.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="NOB74_002483"
     CDS             complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="NOB74_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HCI1221622.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="NOB74_002484"
     CDS             complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="NOB74_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HCI1221623.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="NOB74_002485"
     CDS             complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="NOB74_002485"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HCI1221624.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            complement(6389..7318)
                     /locus_tag="NOB74_002486"
     CDS             complement(6389..7318)
                     /locus_tag="NOB74_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI1221625.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            7513..8196
                     /locus_tag="NOB74_002487"
     CDS             7513..8196
                     /locus_tag="NOB74_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HCI1221626.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            8357..9400
                     /locus_tag="NOB74_002488"
     CDS             8357..9400
                     /locus_tag="NOB74_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1221627.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
BASE COUNT         2893 a         1933 c         1869 g         2737 t
ORIGIN      
        1 gctatttttc tcggttttca ttagcgactc gtgaagccgt tcaatggatt gttattgata
       61 tgtatgcgcc ttatgtttca ttggtgaaaa agcttttccc gaatgctcag ttgatcatcg
      121 accgtttcca catcgtccaa catattggca gaaccttctt gaatcatcga gtgaaagaaa
      181 ccacggcacg gcttaaagga acttcccact ctcaacgagg gttagggaaa aaattgaaac
      241 gctattggaa actcctacaa aaagaagaag caaagttaaa ctacgaaaaa agggtttggc
      301 gtgccagttt taaagattat ttgactgaaa gtgagattgt cgatcgactg ttatctgctt
      361 gtcccaacct gcgccaaggc tatcagttat accaagacat tctttatgcg gtaaagaaaa
      421 gagatcagtc attatttgag gactgtttaa acagagaagt cagcggtctt cctgaaacct
      481 atacaaccac tttacgaacg tttaaaaagt ttctgccaca gatccaaaat gcgcttcact
      541 acagctattc aaatggacca ttggaatgtt taaacaacca catcaaagta ttaaaacgca
      601 atgcgtacgg ctttcgcagc ttttacaatt tcaaactacg gatcatgatt cgtcatggca
      661 aaacattttt aaccaaataa acagaacaga aagagagttt cttctttctg ttctgtccaa
      721 attattctaa gatttctctt taccaacatc atttgacaaa gagcctgtat ttattactgt
      781 cgaggacaat ggcatcggca tgattgaaga ggaacaaaaa aacatttggg atcgctatta
      841 taaagccgat ccgtcaagta aaaatacaaa gataggcgag tcaggtcttg gattatcaat
      901 cgtgaaggaa ctagtgcgcc tgcaccacgg ttcaattgaa gtgaccagcc gaaaaaatga
      961 aggaacgacc ttcctgatac aatttccaaa agaaaaataa aattaccagt aaaaaaccgt
     1021 ggagagatag ctgctattga tttttgctat gtcttttctt tgagaggtat ccggtatggt
     1081 ggagtgtctg aaaaataaaa aaatggaggc caattttgtg aaagctgtta tttctggaag
     1141 tattgttttc caagaagaat atcgagatat ggaaaaagat ttcagtaaaa aaggcattga
     1201 attaattgat tatcctcgct catgtccgat cctagacaaa gagtatccag aaatcttgac
     1261 gacttttttt taaatatcgc agcagcggat ttattttttg tatttaatca agatcggaaa
     1321 ggggtattag gctatattgg tgccgcaact ttttcagaaa tgaagtattg tctgatgcaa
     1381 aatcttattc atggaaaaag gatcaaaata gtcttattta aggaaccatc agaggaaaat
     1441 tttttgtttt gatgaggtag atcgctggct aaagaatggc tggatggaaa tcagacagcc
     1501 taacaatttg gcataacaaa ggtgtgggca aaaaactgct cacacctttt tgaatttttt
     1561 atttatatac tacaaaatca cttgaaaatt atgattcact tttgcttcga tgcgtgggtg
     1621 aatattcaaa tagtcggcaa ttaattcggt catgtcgatt tggatttctc ggacaatttt
     1681 ctccgcacca aacatcgcat aatttcctcc gccgattgcc cgatattgat ttgtcaccac
     1741 ttccagcatt tgttgcggaa gaacggggtg acctttaaaa cgaagttcgg taatccgttg
     1801 tccaacaggc tgtttcatat caatagtgta ctgaatccct tcatacatgt cataattgta
     1861 gtactggggc ttaggctgaa taaaggctgg attgaatacg atttggttat tttctacagc
     1921 taaataattt gcggtctgct ccaacgccgc tctcaaatct gcaccattta tttgaatcac
     1981 tgccagagta ttcggataaa tatagttggt gatgacgtcc cgcatcgtga tcgtctcacc
     2041 aaagcctttt ccttcattat tgaataacgc agttccagaa atctctgagc cgctggcaaa
     2101 taattgtaca cgattaataa actctacata gggatgttcc tcaagacgag cctgcatcgg
     2161 atcattaata cgcatatttc cgttcacttt acctaagggt tgatccaacc atttctctag
     2221 tttttcttct accggtacga tcgctgcaag aatttctgga tcaggctctg atttttcaac
     2281 tgagtgtaaa gcaacctggt gatctgtaac aaccacttgc ccctcttttt tctcgacggt
     2341 aagacgaatt tcaccgatga actcgccacg atagcctggt tgaacaacgg gaactccatg
     2401 aaccgtttca gcaattttcc ggtgctgatg accggtgaaa agggcgtcaa tgccttcaac
     2461 ctgctgcaat agctcgtagc cttcattctc tccagttagc gcttctgtgt cctcaccggt
     2521 taacaagtct ttttcaaatc cgccgtggta actaacgatt accaagtctg cttgtttcct
     2581 taatagagga acatattctt ttgctgtttc gacgatactc ttaaacgtaa ttcctgctaa
     2641 ggtttctggc ttttcccagt gaggaatgta ttgtgtcgtt aatcccaaga tagcaatttt
     2701 tacacccacc ttttcgataa tcttataggc gtttccaaag tatggttggt catttttgtt
     2761 caccatattg gctcctaata taggcgcttg ataattctta atcgcttcct cgagataatc
     2821 cacaccatag ttaaactcat gatttcccaa cacttgaaca tcatagctca tttggttaat
     2881 caagtctgta agctctttgg ctgaaccata ttctttagca agataataac tcaaaggaga
     2941 cccttggatg aaatcaccat tttcgatcgt aattaccggt ccatctgctt ttgcccgtaa
     3001 ttccttcagt ttcgacgata ctttagccgt tcctaaggcc agatcggttc tgccggaata
     3061 gtctgttggt gaaacatagc catgcatatc acttgtctct aaaaacgtaa tgttcattct
     3121 gcgtgctcct ttagctgact caaaatagaa aaaccgaagc gtattcagct gttcggtctc
     3181 tttttttgat ttataatgcc ttaatccttc atttgaagtg tttttaaaat gttgcctgga
     3241 ataaagtttt ctgttgtctg gcgaacaatc cttccttgat cgagatgata aaggttatac
     3301 ccatgacgtt cttcaaagcg tacgaagcca tcgccttcat cttcaccaac aaaggacata
     3361 ctcgatacag taaaataggg gatcccatta atttcatcag taaatgtgtg atgggtatga
     3421 ccgtttagga tacagcgaat atcgtaaggt gcgattagct tcaagaaacg ttcggtacca
     3481 ggccattttg gtatactgct ttggtgagac agtagatgat gatgggtgac caagaaaatc
     3541 ggttggtctt tttcttgctc taaggctttt ttcagccatt gaaattgctg atcgtccact
     3601 ataccatctg cgtatccata gcttgaatta tcaaaggaaa tcactgtaaa ctcaggatat
     3661 ttgactatct ggttgtacgg ggcagaagag gcggcttcat cgcaccagcc tacccaaaaa
     3721 tgttctttga tatcgtgatt gcctagagta acaagaatcg tcgtttctcc tagcgcattt
     3781 tccagccaag tcttcaagta tcgataatcg tctatttcgc catcttcggt taaatctccg
     3841 ctgataatca caaggtccaa gggtgtttgc tgcaggagat gatgaatgca ttgctccaga
     3901 gggataaggg gattctgcat cgtagccagc attcccttat agccttcttc acaagcctca
     3961 tactctctgc gaaagtgtat atctgatata tgcaatatat tcattcttat ctcaatctct
     4021 ttcttataat tccggttatt tgatctaaaa taaacacggt tacgactacg ccaatcaaaa
     4081 taatactcac tttgctccaa gaccgagttt gaatcgcgaa tatcaatgga gcaccgattc
     4141 cgccagcgcc aactaagcct aaggtagccg cactacgaac cgctatttca aaatgattta
     4201 atgctaaaga acaataaatc ggcatcaaat aggggatgcg aacaaagaaa atcgtttgcc
     4261 aaaaatttgc tcctaccgca tgcatttctt caacaagtcg ctcatccatc gcttccattt
     4321 cttctgtaaa aagtttgcca agcattccga tctgatggac gccaatcgcc ataacaccag
     4381 caaaggggcc aggtccgacg actttcacaa aaataattgc aaaaactagt tcaggaaaag
     4441 ctcgtaaaac attacagata agcttgccaa tttttgttac ccatggatgt gcttgccaga
     4501 ggttaaccgc actgatcaag gtaatgggaa tcgctaatac cgtagcgatc attgtcccta
     4561 aacaggcgat tccaatggtt aataatagca aactaatcaa atcctcgccg ctgccatcat
     4621 atagaaactg ccaatcaggc tgacctaacc ctctcaaaac gtccattccc atggaaggag
     4681 agaaggtgct taatccagag taatccagag tagcggccga caaaataacg agaatcacta
     4741 aagcaactaa tgataaaagg gttcttctgt tcatttcacg aagcatcata acagggacct
     4801 cctgacacgt tcacttaatt tatcaacgat cgcgacagtt actaggatcg ttagaataat
     4861 gattgaaact cgttcataat tcaaaagcgc aagtgaggaa tttagaataa cgccaatacc
     4921 accagctccg acatatccaa ggacagtaga agcacgaaca ttcacctcaa acgcgtaaaa
     4981 agcatagctc gcaaactgac tcaaaacttg tggagcgatc gaccaaatag cgatttgcat
     5041 tttatttgct ccaacagccg cagcggcttc aatcgggcca aagtcaatgg tttcaattgc
     5101 ttgaaacatt aattgtgaca ccataccaaa agtaaagaca gcgatagtca acacgccagt
     5161 cgcttcacca attccaaaca cagcaacaaa aagcgcggct aaaagcaggg tagggatggt
     5221 ccgtactaaa cctaaaagaa aacgaaagat ggtagaaaga agacggtttt ctgtcactac
     5281 agtggtcgct aaaaaactaa cagggatcgc taaaattaag ccaatgaccg ttccaagcaa
     5341 agacatttga agtgttttca ccataggctc gactaattta ggtaaatagc taaagtctgg
     5401 atgaatgaag cgtgataaaa agacagtcat ttgattggag ttttgaaaaa cctgagaaaa
     5461 atcagctgac gtgatccagg cacttccttg aaaacaaaca attaagaaca gaagaataag
     5521 caggtgttta taccatttaa agtgaacggt ttctttcaag ctcatcgatt tcgcctgcct
     5581 tttcttcaaa gattgcattg ccataaattt gctctaagcg ttcatcggtt aagtcgtctg
     5641 gacgaccatc aaagacaacc tgagcagctt ttaacgcgag cacacgcgta gaaaactcac
     5701 gagccagagg gactgaatgc agattgacaa tgactgtttt atccatcgtt tgattgatat
     5761 tttttaggtc catcataacc ttttgagtcg tgattggatc taatgatgca acgggttcat
     5821 ccgctaaaat aatgggggct tgctgcacga gtgctcgcgc aatggatact cgctgttgtt
     5881 gcccaccact gagctcatca ctgcgtgtct gcaatttatc agacaaacca actttttcca
     5941 gtgcttcctt tgtctgctgg tagtcttcct tcgtaaaaag acctaaaata cttttccaag
     6001 tggagtaata gcccaaacgt ccagatagca catttttctg aaccgtacta cgctttacca
     6061 gattgaagct ttgcgagatt agaccaatct ggcggcgaat ctgtcgcagc tcttttttat
     6121 tcgcttttgt aatagaggtt ccattaatgc gaatatctcc tttggtggtt tctgccaagc
     6181 gattgatact gcgcagcaga gtgctctttc cagcaccact caaccctatg atggaaacaa
     6241 attctccatc ttcaattgtt aagtcaatat ccttcaagcc aacaacgcca ttgggataga
     6301 ccttcgaaac attgtcaaaa ataatcatta tccttctcca tttttttaag tgtaagcaaa
     6361 aaaaagcttg ctgacactta ctgatgtttt attctgctgc ttttttcgtg tagtctctga
     6421 tcgtgtcata ggcagaatca gcagcttctt catagccctg atgcccccac aaagccattg
     6481 cttctttgcc atctttatca tccttcatat ttaagaaggt ctctttaatt ttcgctttta
     6541 aatcttttga catgtcaggc tgtacagcga ttgcgtcatt cggaatatcg ccttttgtca
     6601 ggtacaggac ttttaaatcc ttaaataaat cattatctgg gaaattcgaa gcaaaaacat
     6661 ttcgcgcgcc ttcaaaaaca aacgccgcat ccatttgctt gttcaacact gcggtaatct
     6721 cactcggaat atcattcaca gtggtcatct ttgtatctgc agtaggatca atcccagcat
     6781 ctttcaattc agcgacagga tagatgtagc cgctagcaga gttaggactt aaggttgcga
     6841 tattttttcc ttttaaatca gttaacttat tcaatccgct atcggcacga accaatactt
     6901 ctcctttaaa ggtgttcgta agtttgtcct ttaatggcaa gccagtttct tgatcataat
     6961 cgccgagctg agaagtcagg attgcatctg cagctccagc atcctttgct tgaacatagg
     7021 ctgcaggcgg cataattccg acatcgactt gaccagaaga catcgcttcg acgatcgttg
     7081 aataatcagt agctaacgtc acttctacct cacgatctaa ctttttcgat aaatacttag
     7141 caaatggttt tgcttttgcc tccatactac catcattgtt tgttggaacg aattgaacaa
     7201 ctaatttttc tttgctctct ttttctgagc tgctacttgt attcccagaa ccgcaggccg
     7261 ccaaagtggt caataacatg actccgatga acccttttgc taactgtttg aactgcattt
     7321 ttctcctcct gttggatata atttctaata cgtctaaatc atagcaggga atcaaaatca
     7381 atgaagtgac gcacgtccta ttttacacaa cttttacata caatttacaa acaattataa
     7441 ataattattc gtattgagcc gaaaaacaat ctaagctata ataaagaaaa acttcttaga
     7501 ggtgacgatt tcatgaaaaa aatccatgat acgaagcaat taactgctta cgttgagaag
     7561 cacaacctgc aggattatat ggattcagat atattggcaa tggcttcttt actttttttt
     7621 gaaaaggaag agcacctcat tcaaacggga aaaacctcag attatttgta ttttttagtg
     7681 gatgggacgg taatggtgta ctcgtattct tctgatacac aaaatatttg catcgattac
     7741 gcaaagcccg ctacaccact cggcgaagcc tcttcattgt gggaattatc gccgaaaagc
     7801 agcgttaaag cagtgactaa gtgcatctgt atcagcattc cgctaaatca atatcgaaca
     7861 cagcttcaaa aagatgttcg ctttttgcag aatatttgcc agttactaag ttatcgttta
     7921 aattccggga taaatttggc gaactcactg acagaacctg ttgaaactcg tttagcaaag
     7981 tttattttga cccatcacga aaacgaacgt ttctcatttc ggttaaccac ctgcgcctca
     8041 atcttaaatg tcagttatcg acatctttta cgaacaatca cgaattttcg tgaggagaat
     8101 attatcgaaa agaaaaagaa ttattacttg attcatgata tcgaagcttt agaggactta
     8161 gctgagaata taagtagtcc agtaaaagca gaataacagc tataaaaaaa cagcagtcag
     8221 aagtgattgc tggttttttg atagtggaga aattgggaaa cggaaaatct tcgttgaaga
     8281 gtagtgttct atatattggt atgctatact tttaaaagtt caatgtgtca agacacataa
     8341 aaaggggaga aaaattttga agaaaatact tgtttcattg ttgtttttgg tgtcattagt
     8401 aacgttagtc ggctgtagtc agtctcaggg ggagaagcaa agtgaaaaag agaaaagtaa
     8461 aatcgctttg gttcttggat ttggcggggt tgatgaccgc tccttcaatc aagctggctg
     8521 ggaaggatta gaggcttggg gaaaagagaa aaagctgaca gcaaaaaaag attttacgta
     8581 tatagaaacg aacaatccag aggataacag taccaatatc gatcaggcaa tcagaaacgg
     8641 ctttaccacc attattagct tgagctactt gcaagcagag gaactggaaa atgctgctaa
     8701 agataatcca aagttgaaat ttgccttggt agatggtgag attactggga aaaagaatat
     8761 ctcatcagca acctttaaag atcaagaaag tgcgtattta gcaggactag ctgccgcata
     8821 tacgacaaaa agtgatcaag taggctttat tggtggaatg gaagggcccg tgatccaacg
     8881 tttccaaagc ggatttgaag ctggcgttaa ggcaggggcc acagcactga acaaggaaat
     8941 tactgttaac gtacaatatg ctgcatccta tgattcgcta gataaaggaa aagctattgc
     9001 tgcttctatg tacaaagagg gagtcgatat tctttatcag gcggcaggaa gtactggagc
     9061 tggggtgttc caagaagcaa aagcccgcaa tgaaaacgac tatagcagaa aagtatgggt
     9121 gattggtgta gatcgcgatc aagcggatga aggggattat aaaatggaga acggcgagac
     9181 agggaatttc acgttgactt ctacaaagaa aaatgtcggt gcagaagtca aagaatttgc
     9241 agaaacttct cataacgata aatttcctgg cggcaagcat ttgacctttg gtttgaaaga
     9301 agaaggggta gatctgacaa aaggacaatt atcagaggaa gcctatcagg cagtttcaga
     9361 cgcaaaagag aaaatcatca gtggtgattt cagactgtag acaaagtcca ttttatggat
     9421 gatgtctaca gt
//
LOCUS       DAIGWC010000093         8684 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.096, whole genome shotgun sequence.
ACCESSION   DAIGWC010000093 DAIGWC010000000
VERSION     DAIGWC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8684
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.096"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(557..1597)
                     /locus_tag="NOB74_002489"
     CDS             complement(557..1597)
                     /locus_tag="NOB74_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI1221628.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSSYSEAQQTVQTIHNAKRKAEELEQTIVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1945..2271)
                     /locus_tag="NOB74_002490"
     CDS             complement(1945..2271)
                     /locus_tag="NOB74_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221629.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNYKPKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2258..3061)
                     /locus_tag="NOB74_002491"
     CDS             complement(2258..3061)
                     /locus_tag="NOB74_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI1221630.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3412..3702)
                     /locus_tag="NOB74_002492"
     CDS             complement(3412..3702)
                     /locus_tag="NOB74_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HCI1221631.1"
                     /translation="MSINTFVYSHPINVYIIKYLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3838..4017)
                     /locus_tag="NOB74_002493"
     CDS             complement(3838..4017)
                     /locus_tag="NOB74_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221632.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLFI"
     gene            complement(4014..4364)
                     /locus_tag="NOB74_002494"
     CDS             complement(4014..4364)
                     /locus_tag="NOB74_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221633.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRANQNLAKEQMRTE
                     EIAEILNASVIKNRSVCIQKEERNAEGYYPDDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4357..5682)
                     /locus_tag="NOB74_002495"
     CDS             complement(4357..5682)
                     /locus_tag="NOB74_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCI1221634.1"
                     /translation="MLDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKNLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYQNVPDKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIKDLANWNPYTIKSRLGVIGLQLYFHANGIDRTDIAIAPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHHCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTRELQDYCLFLFNKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDDEK
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            complement(5791..5994)
                     /locus_tag="NOB74_002496"
     CDS             complement(5791..5994)
                     /locus_tag="NOB74_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HCI1221635.1"
                     /translation="MKEQQLGYTLWGRPLYGLERRTAVSIDCACGELIQLNIQTKQYN
                     CKNCGNCYQFIDQDFQLLNEKNK"
     gene            complement(6154..6729)
                     /locus_tag="NOB74_002497"
     CDS             complement(6154..6729)
                     /locus_tag="NOB74_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1221636.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMDRDMIVERTQEGKLFAKKNNPNFKEGRPKATITPKKRHAYELI
                     TSGKSYKEVEAITGFSRSTLFRIKKQIEASE"
     gene            complement(6745..7350)
                     /locus_tag="NOB74_002498"
     CDS             complement(6745..7350)
                     /locus_tag="NOB74_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HCI1221637.1"
                     /translation="MILENKLGLTNQVELAKAEEKLSKQKAKELYDSGKINEIEVGTF
                     KGLSEIHDFLFSEIYDFAGKIRTVNIAKGNFRFAPVMYLEQSLNHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(7437..8258)
                     /locus_tag="NOB74_002499"
     CDS             complement(7437..8258)
                     /locus_tag="NOB74_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1221638.1"
                     /translation="MYQFLKTGATILNYYQQYKENKKRCGRRSIALPEEQKEYVQKRV
                     VQGWTPDVIVGRSEMKLDCSVRTLYRMFQTGAFNVRDLPMKGKRKPNGHQEKRGKQAF
                     RRSIHERIKEHPEFENEFGHLEGDTIVGRKHKSAVITLVERLSKVIITLKPAGRQAMD
                     IENRINHWFQTVPKHLFKSITFDCGKEFSNWKAMGNQNDIDIYFADPGTPSQRALNEH
                     SNGLLRRDGLVKAMDFNEVSESFIEYRKHFLYSILSSFKFSIDYIYCEFCRGSET"
BASE COUNT         2544 a         1631 c         1330 g         3179 t
ORIGIN      
        1 ttgcgggtaa taccgtaaca ctgaagggca cgcattaagg cgtcatctta atgctttcct
       61 gtaggacact gacggagatt accagtctcc cgagccttac aggggccttt cttttttttg
      121 tattttcaat tatcacaatt tatcgtccaa aagtgcagaa cgaaaatcaa ttcatcacaa
      181 gcatatcaga caattaaatt taaaacaact aaaaatatac aaaaaagtgt aattgaatat
      241 tagcagcact gcctgaaaag aagtaatatc aggcttttca gcttggggaa ataagtgaat
      301 tacctctctt catgaattat tataactcaa aaaagcacat atgcaaacac tagttcccta
      361 tttttttgaa tgaaaaataa ctaaaatatc taacgattat gactttaaaa cctacgtttg
      421 tgattgtttt cataaacttt taatctaaaa actccggaat aataactatt tatttgtaac
      481 atttgtaata aaattaaaat cataaaaaag ttctaattta aaattgatca tttttatagt
      541 gatcgctttt tatcaactac tctagccaat tttccgtact aactgttggt aattcgttaa
      601 atgtttctct ttgttcgttt gcaagctttg ccgcaatagc tttttcgaca aaccaatttt
      661 ttacataaac gaaaattaga ttctgcaaat tgtttacttt ttcagttttt tgtttttgat
      721 aagctttcag taaagtcata tataatcctt tgtcagcatc aattccataa gattcaagtt
      781 cttcataaac aacaatagtt tgctctaatt cttcagcttt tctctttgca ttatgaatag
      841 tttggacggt ttgttgagct tcactgtaac ttgaagaaaa tgtttttatc aagttcaata
      901 cattttctgg tacaaatgta tttatactgt cctctttcat gatgtcgacg aagttatcta
      961 gtaaaacttg attttgtaac tgatcagttt cagtgtctat tatgtgtcta ttagtgtcta
     1021 tagaattaga atagaataga ttgtctgcga ttttcgcaat tacggttgag tccttgatat
     1081 gactggattt tgccgtattt gcgattttcg caattacggt ggtatcattg atttctcgcg
     1141 gttttgccgt atttgcgatt ttcgcaatta cggtggtatc agtattgtct tcctcttcca
     1201 tgattttaaa gacgtcttga ttcgttactt ctggcttgcc taagtacaat aaattaggca
     1261 tagattcaat cttaccatca cgtttattta ctcttcctct cttctgtttc agaagacctg
     1321 ctttttctaa ttcctttttg attttagata ctttaccttc gcggcattgt aacagtttca
     1381 ttaattcttc aactgtgaat atgaagaata tattatcatc agaatctacc cagttatttt
     1441 tgactgaata atcaaatcga tctttaagta gcatataagc aatttttgca tcatttgata
     1501 gatccatgta tttttcgtta gtaaaaaata ccttaggcat ttgataatat ttttcacgat
     1561 aaatttcttt tgatttgtaa taattaaaat cattcatagc caatcctctt tctgtaggat
     1621 agcgttttgt tcaaaactgt gttacaatga attaaacaaa tatatctatc cactatatat
     1681 tttctactgc tgataagtcg ccaaactttg ttaaagcagt agtctttttt tatctttttt
     1741 tagtttacct taaaaaataa attaaagcaa accgctctat ttcaaggttt aagctcatat
     1801 caactatatc acgatattac aataacatta tatcacgata ttgcgatatt acaatatgaa
     1861 gataagcgac ttatcagctt tgatactact gctttttata aaaaaaatat cacgatatta
     1921 tgatatcgtg atattgaatg taaattaaat tttattttgt ttctttgcta gtttatatcc
     1981 ttcaatcaag tattcttcag gtatggattt taatagcgca tcttctataa cgtctggttt
     2041 acttttgtct gattcagcaa tagtcgtcca atatttgagt gctgacatta gaattggatt
     2101 tatgcgaatg ctatctgctg ttcttacact acttccttga tcttttatga ctttacttat
     2161 atttttcttg gttaattcga tttcttctac ttcttttggt ttgtagttct ttttattttt
     2221 atttcctagt agtctactta ctgcagcttg actgcgatta tcttctgcca tcaaaatcac
     2281 caacttcttt taaatattct tctgtaaatg ctttatagtc atcttcagct gttgagggtt
     2341 tattaaaatt gattagatct gatccagcag cttgcgcttc gtcaacggtt attgtcctac
     2401 gaatataagt tttgaaaatt tttgcaccaa tgactctaga aatttcggtt gctgcagacg
     2461 tcatttcttt agaaatgtta taacgcttat tatacttagt aaataggact cctcgtactt
     2521 caagcttgtc gttcgtatat tcttttaccg tttcaatagt ttcacttaac tttattagtc
     2581 cttttaatga gaaatacgca gcttcaactg gaatgataat ttcatcagaa acagtaaatg
     2641 cgttgactgt aagcattcct aaacttggtg gacaatcaat tataatataa tcatagttgt
     2701 ccttgattgg ttgaagtact cttttaagcc tgtgttcact tcctacttga gtaaattccc
     2761 tttctgcaga agaaagggct atgtcggctg gcaaaacatc aattccttta tagtccagaa
     2821 tagcatctgt aatgtcagcc tcccctttta atacttcata aattgtaggt tggtttgttc
     2881 catctatatc gaaacctaca ttatctgtag catttccctg aggatcaatg tccactaaaa
     2941 gtacattttt accgtaaaca aatttcaaac atgctgctaa attaacgcta gtcgtagttt
     3001 tagaaactcc acctttttga ttggctactg acaatattct tgccattaaa atatccccca
     3061 ttcgtcttat attataatat aattatatca tgatattgtg atattgcaat atcgtatttg
     3121 cattatattg taatattgtg taattatttt gttttaaaga tatatatcgg ttcggatata
     3181 aagatcattc atatgttatt cgaaattaaa ataatcactt tttttaattt aaaatttttt
     3241 actaatgata agaaatatgt tttgtgagca gcaactagaa taatttaaac attactaaac
     3301 tgtctatatt gttactaata attcccttct tatagtgcat tttcttagaa aaaacaatat
     3361 tacgatatca tgatattaag atatcgtaat attatacaat tgtgattgat attatatatg
     3421 tttttttatt tttttatcat gtttaatctt gaaggaatca tattcttttt ctaaagacag
     3481 gagcttttca taaacatcag acatgttcaa actagaggcc aggcttaaat cataaacgaa
     3541 tgaagcaggt aatgatttta ttctacgttg tcgggttatc cagcttgcaa ccgttccttg
     3601 tgggtaggca tataactcac aaaattgttc tacagtgatt cctaaatatt tgataatgta
     3661 aacattgatc gggtgcgagt aaacaaatgt attgatggac atggtgcgta agcctacttt
     3721 cttttattat tgcgtttgca ataatagttt aacacacgca ttattctagt atctactcct
     3781 atttgtaaaa acaaaaaagg attcatagag ataactctat agaatccgta aaatacctta
     3841 tataaataac gggaaaatat aaaacctaaa attatgataa cctgctgcag cttctacata
     3901 gaaagagaaa cgctcaacac caacctcatt tatcaaacgt tggccatacc cccaaatctc
     3961 ttctgatagc tgatcaaagg ttatatactt tagctcatat tgctggataa tgttcattct
     4021 aatcgactcc atttattatc ctggtaaaat tcgatatgac gtatttcgtc gtagtgaatt
     4081 ttgtctttgc caacgtagat tcccagctca tcactaccta agatctttcc aacaatatcg
     4141 tctggatagt atccttcagc gtttcgttct tctttttgaa tacatactga tctatttttt
     4201 atgactgaag cgttcaatat ttccgcaatc tcttcagtcc tcatttgttc ctttgctaaa
     4261 ttttgatttg cacgttgctc attatctgca tcgatctctt cagtatgatc cgataaatag
     4321 aaacctgccc atttcaatcg tcctcgatcg ttatagtcaa tcatttttaa gcccccctgc
     4381 gccgcctgca tggccaccaa ccaacgtgct tctagtaata ctacgagcgc cttctaacat
     4441 cgaagaagca tgtacaattg acgtaaaacc atacttctgc ctaattttat ctattatttt
     4501 gtctagtttt tcgtcatcaa tctgtttttg tggatcacta aacaaatcca gctgaagcga
     4561 atcagtataa actagcttgc tgtaagtgat tccgacatgg cggacttctt gtccctcata
     4621 gtatttatta aataagaaca gacaatagtc ttgtagctct cttgtattat ctgtgatagg
     4681 tatcttcatc tggtgtgaaa accctggtct cgtttctaaa atcgacgttc caatgtgtaa
     4741 atgaacacaa cctgttttac agtggtgttg cctaatacgg attgctactt gctcagccat
     4801 ttcttttacg accagttcga tttcatttct tctagtataa tctcgtggta gcacttgtga
     4861 attgccatat gatttttcct ttgtcggttc tggtgcgatt gctatgtcag ttcgatcaat
     4921 accatttgca tggaagtaca gctgtaaccc aatcacacct aaacggctct taatggtgta
     4981 tggattccaa ttagctaaat ctttgatact catgatcccc atttggttga gccttttttt
     5041 cattcgagaa ccaatacccc aaaagtctgt catttcagga atattccata ctttatcagg
     5101 aacattttga tacgtccatt cggcaataaa tccttcatta tgcttcgctt cattgtctaa
     5161 ggctagttta gccaaaagag gattatcgcc aacacctact gtagcaatca atcctagctc
     5221 ttctttaata cgttcttgga tcatttgagc gagattcttc cttcgctgac ttcgtgttcc
     5281 ttcagtcgta aaaagattca gtgatcgggt cacttttaag attgattcat cgatcgagta
     5341 aatcagtaga tcttcatcag ccacatatct tctgaaaata ttatttacct gcatattacg
     5401 cttaatataa aggttcatac gtggtggaac aacatgtaat gttttaggga aaggctgtgg
     5461 tagatcccgt ggtctgctga cattagaaat accatatttc ttctttgcag ctggtgaaga
     5521 agctaaaatc aaccctgatc ctgtattatc cgctcgactc atgacaacta attcagtcgt
     5581 taatggatct aaatttcttt ctatacattc gacacttgcg taaaaacttt tcatatcgat
     5641 tagaaagtag tcattgactg gctcttttga gtaatcaagc ataaagttct ccccctcttc
     5701 tctcatatta tacaaacata cgttcgtgtt tgcaacgagg atcttctcta aatagaaaaa
     5761 tagccagaca attgtctgac tataataaac ctatttgttt ttttcgttta gcaattggaa
     5821 gtcttgatca atgaattggt aacaattccc acaattttta caattgtatt gtttcgtttg
     5881 aatattgagt tgaatcaact caccacaagc acagtcaatc gatacagccg ttcttcgttc
     5941 taatccgtat aatggacgtc cccaaagagt gtagcctaat tgttgttctt tcatttactt
     6001 cgttcctccc taaaaatatg tctattcgta gctggtatga cgcttcgttc gaccaatgat
     6061 acatcttaat gagtgaacct gaccttagaa tgctcgtata aacaacgatt tatttgattt
     6121 aaaagagatt tttatattaa ttttatcaat cttctactca ctcgcttcta tttgtttctt
     6181 aattctaaaa agtgtactac gactgaaacc cgttatggct tccacttctt tatacgattt
     6241 gccggaagta atcaattcat atgcatgcct cttctttggt gtgattgttg ctttcggacg
     6301 tccctcttta aaattaggat tattcttttt cgcaaataat ttcccttcct gagtacgttc
     6361 tacaatcata tcacggtcca tttcagctac actcaacaac gtacgtgtaa ccattcgacc
     6421 catcgatgta ttttcgatcg tccctagatt caatacctta atcgtgacgt tatcatcgag
     6481 taaaggttca atgatctcta gtgcttctct tgtattacgg gcgaatcgat caagtttcgt
     6541 aacaacgatt tcgtctccag gcttcagacc agccaacagc tgattaaact ttggccgatc
     6601 tcgtttcgta cctgtaaatt tttcagaaaa aatattcttc ttctcaacac cgttctcaag
     6661 tagctgttgt atctgttcct ttgtactttg agaagcggtt gagacacgtg catagccata
     6721 ttttgtcatt taactcacct gcttttacaa atcatctatc gtatactcag agtatccttc
     6781 atagaagtag ctgacatcga ttcctttcat atataactca cgatcgtcaa ttttatcagt
     6841 cagggcattg gaaatgagat agcgtatttc caagtcattt attggactgc gctccattgc
     6901 agaaagatag tctgctttat cgatcaagtt ccaatcgacc actttttgca attcttcctt
     6961 taaaatgaga tccagccaaa ttctagtact gcgcccgttt ccttcgcgaa aagggtgagc
     7021 gatattcatt tccacgtatt tcttaataat ctcttcgaaa gaagtttgcg gcatctgatc
     7081 aatatgattt aaagattgtt ctaggtacat gaccggcgca aaacgaaaat ttccttttgc
     7141 aatattaact gtccgaattt ttcctgcaaa atcataaatt tctgaaaaga gaaaatcatg
     7201 aatttcagac aagcctttaa acgtgccgac ttcgatttca tttatttttc cagaatcata
     7261 taattctttt gctttttgct tactgagttt ttcttcagcc ttggccaact caacctgatt
     7321 cgttaaaccc aatttatttt ctaaaatcat ggaaaatccc cttaactttt tgacataagt
     7381 ttatgaaaca ctacaaatcc tattgtatcg cgaatttaac catgtgtcaa aaactattaa
     7441 gtttctgacc ctctacaaaa ttcacaatag atataatcta ttgaaaattt aaaagaagac
     7501 aaaatagagt acagaaaatg ttttctgtac tctataaatg attctgatac ttcattgaag
     7561 tccatggctt taactaatcc atcacgacgt aataatccat ttgaatgttc atttagagcg
     7621 cgttgtgacg gggtgcctgg atccgcaaaa taaatatcaa tatcattttg atttcccata
     7681 gctttccaat ttgaaaattc tttcccacag tcaaacgtaa ttgatttaaa cagatgttta
     7741 ggaaccgttt gaaaccaatg attaattcga ttttcaatgt ccattgcctg tctaccggct
     7801 ggcttcaatg taataatcac ttttgacaaa cgttccacca atgtaataac agcacttttg
     7861 tgttttcgac cgacaatagt gtctccttca agatggccaa actcgttttc aaattctgga
     7921 tgctccttga tgcgctcatg tatactgcgc cgaaaagctt gtttcccacg tttttcttgg
     7981 tgtccatttg gttttcgttt gcctttcata ggcaaatcac gcacattaaa tgcgccagtt
     8041 tgaaacattc gatacagtgt acggactgaa caatcaagtt tcatttccga gcggccgaca
     8101 atcacatccg gtgtccaccc ttgaacaacc ctcttttgaa catattcttt ttgttcctct
     8161 ggtaaagcaa tcgagcgtct accgcagcgt tttttgtttt ctttgtattg ttgatagtag
     8221 ttcagtatcg tagcaccagt tttcaaaaat tgatacacgt tatgaatcgt ttgtcacgca
     8281 cgtcctaagc attgcgcagt tttggcaacg gattgattat ttttgaaata agactctatg
     8341 attaccagtt cgtctgttgt aagatgggtg taggtcattt gtactcactc cttaataatt
     8401 ctttggtcgg aactattttg agtgtagcac aaatgatctt tttagttgtc tagcttaatt
     8461 ttacaatcga cgaaaagaat actatgatga gattagtttg aaatttcatt ttgatgagta
     8521 gatattagga actgattgat agaacgaata agttatattg atattttgta tttgcagtat
     8581 ttgaaaaagt tgaagatgat aaggaaaata aagaaacaac aggaacagtc taacttgact
     8641 attcctgttg ttgaaaagat tatgattaat ttactacttt attt
//
LOCUS       DAIGWC010000094         8675 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.097, whole genome shotgun sequence.
ACCESSION   DAIGWC010000094 DAIGWC010000000
VERSION     DAIGWC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.097"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..1101
                     /locus_tag="NOB74_002500"
     CDS             <1..1101
                     /locus_tag="NOB74_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI1221639.1"
                     /translation="KKETIVRFEQYNHMPLVTRLKKQRYTCKNCRTHWTAQSYFVRLS
                     HSIADHVRYKIASLLTEKVSLSFIAKSCQVSLTTVTRTLKEFKSYLPKPSKKILPRVL
                     MVDEFRSHASIEDKMSFICADGETGNLIAVLPTRKLPRLTSYFLGCTNPEEVEFLVTD
                     MNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQALNELRIREMNELRKAGQKSQAEKLKK
                     NWRFLLKNRASINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSAPLKEAYPFFHELV
                     EAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITSAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
     gene            complement(1280..1609)
                     /locus_tag="NOB74_002501"
     CDS             complement(1280..1609)
                     /locus_tag="NOB74_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI1221640.1"
                     /translation="MNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSKYH
                     TKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQRL
                     EERMEEL"
     gene            complement(1599..1871)
                     /locus_tag="NOB74_002502"
     CDS             complement(1599..1871)
                     /locus_tag="NOB74_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HCI1221641.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2322..3125)
                     /locus_tag="NOB74_002503"
     CDS             complement(2322..3125)
                     /locus_tag="NOB74_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI1221642.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3103..4227)
                     /locus_tag="NOB74_002504"
     CDS             complement(3103..4227)
                     /locus_tag="NOB74_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221643.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4243..5058)
                     /locus_tag="NOB74_002505"
     CDS             complement(4243..5058)
                     /locus_tag="NOB74_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1221644.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5048..5920)
                     /locus_tag="NOB74_002506"
     CDS             complement(5048..5920)
                     /locus_tag="NOB74_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1221645.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(6005..7294)
                     /locus_tag="NOB74_002507"
     CDS             complement(6005..7294)
                     /locus_tag="NOB74_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1221646.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7522..8166)
                     /locus_tag="NOB74_002508"
                     /pseudo
     CDS             complement(7522..8166)
                     /locus_tag="NOB74_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2691 a         1850 c         1371 g         2763 t
ORIGIN      
        1 aagaaggaaa cgattgtccg ttttgaacaa tacaatcata tgcctttggt tacgcgccta
       61 aaaaagcaac gctatacctg taaaaactgt cgtacccatt ggacggctca aagttatttt
      121 gtccgactca gccattcaat cgcagatcat gttcgatata aaattgcttc tttactgact
      181 gaaaaagtat ctttgtcttt tattgcgaaa agttgtcagg tatctttgac taccgttact
      241 cgtacattga aagagtttaa aagctattta ccaaagcctt ctaagaagat tctccccaga
      301 gtattgatgg ttgatgaatt tcgttcgcac gcttccatag aagataaaat gagctttatt
      361 tgcgcagatg gtgaaacagg aaacttaatt gctgtcttgc ctacgcgtaa attacctcga
      421 ttaacaagct atttcttagg ctgcaccaat ccagaagaag tagaattctt agtcacagac
      481 atgaacgccg cttacttcca gcttaccaaa cgtgttctgc caaatgcgaa agtagtgatt
      541 gatcggtttc atattgtcaa acacatgaat caggcactca atgagttgcg tatccgtgaa
      601 atgaatgagc ttcgtaaagc aggacagaaa agtcaggcag aaaaactgaa aaagaactgg
      661 cgctttctgc taaaaaatcg tgcaagcatc aaccattatg agtacaaaac atggaaaagt
      721 ttccgagcac caaaataccc atttctcact gaagcaatga tgattgatcg attgcttgag
      781 ttttctgcgc ctctaaagga ggcgtatccc ttttttcatg aattagtcga agcctttcga
      841 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
      901 ggctttcggg agaagcttca aaaccttctg acctatgaag aaggtatcac cagcgcaatg
      961 atctatcctt attccaatgg aaaaattgaa gcgaagaata cccacataaa gacaatgaaa
     1021 cgagtatcct acggatttaa atcattcgag aacatgagaa ttagaatctt tttgatcaat
     1081 caattaatca atgtaagata acaaaaaatc tgaaccagaa tgtggttcat tctgacccgg
     1141 atttgatttt gcacaactca tcagtcctta ttgacaaaga gccaaaaatc tgagccagaa
     1201 tgaggttcat tctgacccag atttgatttt gtacaaccca tcagtcctta ttgacaaaga
     1261 gcccttcttt ttagtattat tataattctt ccatgcgttc ttccagtcgc tgtaaatcgc
     1321 ttggacttaa ttccccaatt tttttccatt tgaccttttt gttgtttttg ggtaattcgt
     1381 ttagagttcc tacgtcaatc caagattctt tttttagtcc tgcctgtttc caatccctta
     1441 tttcaacgta tttcagcttt attttatcgg atttagtatg atattttgaa gtaattgaca
     1501 gaaacgaaat tgtgtccagt ccatttttta gaatatagac aggccggcgt ttaccgccct
     1561 ctgcagctgt gaaagcaacg tagacggttg ctatatcatt agtattcatc ttcattgaac
     1621 cattcttcaa ttttttcgtc agtgtctagt ttttggacag gcaatttttc cgctaatctt
     1681 tgaatattat ggattcgttt acttttttcc gacaattcaa tagaaaatgg gatttttcct
     1741 tgctcaacaa tttgcttata aaaaacggtg acggctgttt tggggctcat gcctagttca
     1801 tcaataatgc tttctgcttc atttttcaat ttttcgtcca tagaaatttg taacttagcc
     1861 attttctcca cctctttctg acaaacacat tatatcacgg aaagagttca aatggaatta
     1921 atacaactac ttttgaactc cttgaaatgc agtgtattta tctaaatata aggaaaggat
     1981 atagtgctaa atggccttga tagatagaaa agtttcaaaa tccgccacag cgataattga
     2041 agcgaacact caacgacaca cagaacagga aaagactcct aaaagaacca aattaactag
     2101 gacgtgtctg aaaactccac aaagatgtgg tatgctctgg taaaaaacga atggcacaac
     2161 cacgaagacc gatatggttc ttggaaaact ttctccaccc tttttgtaat tggagggata
     2221 gtggtttatt gatagcgatt ttccaagttc ttcaagtgga accagacatt gagcaccacg
     2281 gctaaaaagt gaatgaagtc tttattttta atcaataatt tttaatgatt accagtaatt
     2341 ggttttttca tgcgccctat ttctatttga tgtggagtta aataatgctg ataagtaaaa
     2401 atttttccgt caattaaact gccactagtg aatcctgttc tattggtaaa aagagaatag
     2461 tctgggtatt catctacacc aaatgataaa gattcagcca taaactgttt tttaccagca
     2521 aattcagcac tgctaccttg atggatatgt cctacaaaaa tacctaaaat atcactttcg
     2581 gcaatcaatt cagcaaaacc ttccggaact tcagttacaa tagatggatc ttcccacgac
     2641 aatggatgat gaaccaataa aatcgttccc ttttcagcag gtgtacccaa ccactcttgt
     2701 aattgaatca tctgtcctat cgatattttt ccttcgtgct gggtatcttg agcagaatcc
     2761 aaggaaataa ttcgtaaccc attttgattc gtacaatgga tatactctcc cgtttcattg
     2821 ctttcaacac tcattccttc aaagaaaaca ctgcgacgat catgattccc acgacaaaaa
     2881 tagtaaggtg tggttgggaa atattgatcc aacattttcc gtaagacttg ataatcagaa
     2941 atcccccctt catgtactaa atcacctgtt aatagaataa aatcgtacac tgttaacgag
     3001 agttcttgta acaatttttc caatgccaac tgtggatttt taattgttgg aaatagttca
     3061 gcagtaaaca agttagtttg atagttttct ctaaaatgga tatcagagag atgcaaaaag
     3121 cgcatggcta ttccctcttt cttcaataaa ataatcagga tatcctaaat tttcttgcgt
     3181 ctgataatca aaaaaatgca ttctttcagg ttctatgcgg agattgactg catcaccaat
     3241 ctgccaagta ggtttttcat taaggacaat catttctata ccatcgactt taacggtgta
     3301 cgcataactt tgacctaata gctcacgata cttcacttga ccgtgtaaat cgcttgtttc
     3361 ttttgaaaag gttacgtgtt ctggtcttat gcctaaatac aatgagccac taacctgaag
     3421 aagttgtttt tgccaagctg gattcaatgt taaaaattga ctggctacct ttaatgttcc
     3481 ttgatcataa gtaactggca taatattcat gcctggcgaa ccaataaaat ttgcagtaaa
     3541 agtattttta ggtttcgtat aaacattttt cggcgtatca atcatctgaa ttctaccttc
     3601 attcaataaa acaatccggt cagctaacgt catcgcttca atttgatcat gagtgacgta
     3661 gacaaaagtt tgtttataac gttgatgaat ttttaccaat tcttttcgtg catccaatcg
     3721 taaacgcaca tccaaatttg ataacggttc atctaataaa aaataattac tccgtttaac
     3781 caccgcacga gccaatgcta cacgctgccg ttgccctcct gacaaatctt taggaagtcg
     3841 atcttggtat ggcgttaaac ctaacatctt caaagcttct tccaaacggt gctgaatgtc
     3901 agctgtctta attttattcg cccttaatgc aaaaataata ttctccttta cagtcatgtg
     3961 aggatataaa gcataatttt gaaaaaccat tgcgatctct cgttctccac aaggtagctt
     4021 atttgctagt tgtgtaccta aaaaaagctc tccactcgta attttttcca aaccagcaat
     4081 cattctcagc aaagtagatt ttcctgaacc agatggtccc agtaacacaa ttcgttctcc
     4141 agcggccaca gctaaatcaa tttcttttaa aatggtatgt tctccatatt tttttccgat
     4201 atttcttaat tcaagcgttt ctcccatgat ttgtcctcca atttatttaa tacctgcaga
     4261 aacaaaagtc ccgataatat atttttgaaa aattgcatac aagactaacg gtacaaacat
     4321 tgtaattaaa ctaatcgcca ttgctacggt aaaatttgtc ccaccttcag aactaatata
     4381 ggtctgcatc gccaacggca aagtataatt atctactgtc cgtaaaatta ataccggcca
     4441 aacatactca ttccaagagg taataaaaaa ccaaataccg gtagaagtaa tcgcatgtct
     4501 agtaagagga aaaacaattt tactcatgac ggttgtttgt ttgatgttat ccaatgccgc
     4561 cacatctaga aggctcactg gaatttcccg cattgtttgc gtcaataaaa aaatgcccat
     4621 cgcatcagca aattgtggta ttatcacacc ccaagtagta tcaattaaat taagttttgc
     4681 aatcaacaaa taattaggaa tcatcgcaac agtaaaagga atgaacatcg taccaatgat
     4741 gataaagtac cagattttct tccctttgat tcggcaataa gtaaaactat atgccgcaaa
     4801 aaaagctacg cctaacttaa caaccgttat aattgtagca ataaaaaaag tatttctcgt
     4861 aattttgata attggaagat tttcgaacaa atagcaaaaa ttttccaagg taaacggctg
     4921 tggtatcaaa ctagtaatcg tctgataggc atctttcaat ggcttaaaag aattggccat
     4981 aataaacaat aatggataga taataatgat tatgatgaac ataaataaga gatgtggcaa
     5041 ccagcgttta attttcatag taaaccccct tttccacaaa tttaaatatt acccctaaga
     5101 aaacagcaaa tattaataaa gttaaaactg aaattgctga agattctccg actttataca
     5161 tttcaaaagc cttttgataa gcataataga tcacgtttgc actaccatta ttcggtccac
     5221 cacgagtgat gatcttaatc ggagtaaaca catactgcag accttgaaca atggtcatca
     5281 ccaataaata tagtcctgtc gaactactca taggcaacac aattgtaaaa aaaatgcgcc
     5341 agatgggtac acgatccaac ttagctgctt cgatcatctc ttgatcaatt cccacaattg
     5401 ctgcaaaaat gacaatgaaa ttataaccaa aaactttcca agcagtaata cctgcaatca
     5461 cagcaattac ccaaccttgt aaattcatcc acataggcag tcttaaacca aaatttccca
     5521 acaagacagc aattggtccc gataccggat ttaatatcca tgtaaaaacc atccccgcca
     5581 ctaccaaaga aatcacagct ggaataaaaa ataatggttt atacaaattc tgcccttttt
     5641 ctataactat tcctaataaa aaggatgtaa tatatgggaa cacacagctc agcaagacaa
     5701 atagaacggt ataggacaaa gtattcttca acactttatg aaagactgga tcagtcagca
     5761 cctttacata gttggcaaag ccaacaaatt ctttagtggg ggccaccata ttccagtcaa
     5821 aaaaactcaa atagatcgta taaatcaatg gataaaaaac aaacacgccc aacaaaataa
     5881 ttgctggcgc cagatacaaa taacctacat agcgcttcat ttccgacagc ctcctcatcc
     5941 ttatgtcaaa agcagacgac cttgtttttc ctttcttaca ggcgctgtcg tctgcttgct
     6001 ttgcttattt gagtaactca ttaatttcct tttgagtagc tttcatcgtt tcattgacgg
     6061 aattacctga taaaatttta tcccgcatat ccaacaattt ttgttcagct tctaatccag
     6121 catctccagg aaatgaactc caactgacca tcttatccat ctgatcaatt gctggtatca
     6181 tcatctgatt ttcagctaag aaagctttta atccattttg ggcgtctgca acatctttac
     6241 gtggtggtaa ataaccagta ccttctgtcc atttagctaa agattcaaca ctataaagat
     6301 attttaagaa atcccaagtt gcttcctttt tcttatccgt ttgtgatgta acagctaaca
     6361 ttgcgccacc agcaggtagt ttaacttttt tcccttccca acttggtgac tcaactgctt
     6421 tagcagtaaa agtactattt ttttgaatgt tgtccctttg agcaatagtg gtatagacca
     6481 tcgcgacgtt accatcaata aagctttgca caccttgttc ccacgtagtg tgtaatgccg
     6541 tctggtcttt taccatcctt tgatataatt cataagcagc gataccatct ttagaagcaa
     6601 aggtagcttt gccatctttt attacacttg ccccattact ttctaaaatt gcttgttgtg
     6661 cccaattatc agcaggttct tgaatataca cgccatactt tccagttttt tcttttatta
     6721 tcttagaaaa agtttgaact tcttcccaag tttttggacc attttcatcc aagcccgctg
     6781 cttttaatat atcttgattt aaatataaaa ccggattact aatggagtaa ggaataccca
     6841 cttgtttacc atctttttca gacagtgcca tgatattgtc taaaaaatga tctttaaaat
     6901 aatcagcatt atccggatcc acttcttcta ctaaagattg aggattagta tatttgaaat
     6961 tttctgcaaa ataatcttta aaagcccatc ccacttgtac tacgtccggt atttctttgg
     7021 aggcaacaga agcttgtaaa ttttgcatca agcctttata catatcagga ttatattttg
     7081 ctacaacctt cactttgtct tgagattgat tgtatttatc tactaattca ttcactgttt
     7141 ttccacctag ggtatccgca ttaacatgcc aatactctat cgttacacga ccctccgatt
     7201 tttttgttgt cttggtattc ccactaccac aagctgccaa agagatgaca cttaaaacag
     7261 acacaacccc tataacaaga tttttcttta acataacatt aacttcctcc taatttcttt
     7321 atggccattt ttctaatcaa gaaatattat gaactaccaa tgtaaatttc tagttaattt
     7381 tctgtaaata attcgaaatt tgtgcatttc ggggtacagg gtcactggac atatccatca
     7441 agctaagaat aaagccccca tatggtcatg tatcccatct ccaaatctct taactcctct
     7501 gttttgatta taaaatagtt tattctgtgc tcctttcttc cataaatagg cccatgcaca
     7561 acgtgaggtt atattataaa caccacagcg cgcaaggtac tcaatcgttt ctagttcatt
     7621 gactgtccat acagaaaatg tcaatcctag ctgctgcccc acttcacggg ccaacttagt
     7681 taaccatcct tcatgaatat tgacgatttg aacgctttga taggctaatt tctgtaaggt
     7741 atcgatcaaa tctgcttcgg taatatcccc aagttttttc ccttcgaact gattttcaat
     7801 attataaaat atatgctttc cccaaatcgc agcccaagat aattgtacat agccactaag
     7861 aacaatttgt ggccagattt gataggtttg tgccagcgaa aaaacggcca tttccaatcc
     7921 ctcttctttt aaatcacagt taatggtcat ggttgccttc tcattggcca ctgcttgaaa
     7981 cacctgctca agggttaccg aatctgggac aacttcttac ctgtcatggg ctagtattag
     8041 cgtaccatct gtttgctgac gcacatctac ttcaaaacaa agctggcgat ccaaacaaaa
     8101 gcgaagaaat gcccagctat tctcctccgt attgtcacta ccagagtgtg cagtgatcat
     8161 ggtcattttg acccctcctt taattccgtg attttctccc acacgtccac tataccgatg
     8221 aagcgttaat ttcttgttaa tttcttgtaa attccctgcg ttttttcagt aaactagttg
     8281 taaatcttgc atgctccttc ctacgaactc atgaatcgtc gattttgccc ttctagctag
     8341 tttcaccaat taagtagttc tacattcccc gcttttaacc tactacacct ttttttgttt
     8401 tcagctattc cttcttcttg ctgaaagtcc ttgaggttct ttcttacagg ataccatcaa
     8461 ggtgttcaat ggcttattcc cattgaatga ccgagactta ctatcagatt tctgctcgtt
     8521 gaaccaagtc tttgatacag gatttcttcc gtcatcttct cacaaatacc accttgcgtt
     8581 tctctagcga ttggtcgatg tgcaccctcc cagtggactg tcactacccc tttttgctat
     8641 gcctagccca caaaaaaagc tgtcctcaca gacag
//
LOCUS       DAIGWC010000095         8493 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.098, whole genome shotgun sequence.
ACCESSION   DAIGWC010000095 DAIGWC010000000
VERSION     DAIGWC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.098"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..173)
                     /locus_tag="NOB74_002509"
     CDS             complement(<1..173)
                     /locus_tag="NOB74_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1221647.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="NOB74_002510"
     CDS             complement(593..1714)
                     /locus_tag="NOB74_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HCI1221648.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="NOB74_002511"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="NOB74_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HCI1221649.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="NOB74_002512"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="NOB74_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HCI1221650.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="NOB74_002513"
     CDS             complement(4304..5215)
                     /locus_tag="NOB74_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI1221651.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="NOB74_002514"
     CDS             complement(5232..6239)
                     /locus_tag="NOB74_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCI1221652.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="NOB74_002515"
     CDS             complement(6236..8365)
                     /locus_tag="NOB74_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI1221653.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8493)
                     /locus_tag="NOB74_002516"
     CDS             complement(8370..>8493)
                     /locus_tag="NOB74_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI1221654.1"
                     /translation="NGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2680 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg ttt
//
LOCUS       DAIGWC010000096         8317 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.099, whole genome shotgun sequence.
ACCESSION   DAIGWC010000096 DAIGWC010000000
VERSION     DAIGWC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.099"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(16..1167)
                     /locus_tag="NOB74_002517"
     CDS             complement(16..1167)
                     /locus_tag="NOB74_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HCI1221655.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVFLLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(1321..1851)
                     /locus_tag="NOB74_002518"
     CDS             complement(1321..1851)
                     /locus_tag="NOB74_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCI1221656.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(1950..2300)
                     /locus_tag="NOB74_002519"
     CDS             complement(1950..2300)
                     /locus_tag="NOB74_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HCI1221657.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(2457..3986)
                     /gene="ahpF"
                     /locus_tag="NOB74_002520"
     CDS             complement(2457..3986)
                     /gene="ahpF"
                     /locus_tag="NOB74_002520"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HCI1221658.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(3996..4559)
                     /gene="ahpC"
                     /locus_tag="NOB74_002521"
     CDS             complement(3996..4559)
                     /gene="ahpC"
                     /locus_tag="NOB74_002521"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCI1221659.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(4703..5365)
                     /locus_tag="NOB74_002522"
     CDS             complement(4703..5365)
                     /locus_tag="NOB74_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1221660.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            5549..7195
                     /locus_tag="NOB74_002523"
     CDS             5549..7195
                     /locus_tag="NOB74_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HCI1221661.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            7186..8268
                     /gene="uxuA"
                     /locus_tag="NOB74_002524"
     CDS             7186..8268
                     /gene="uxuA"
                     /locus_tag="NOB74_002524"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCI1221662.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
BASE COUNT         2744 a         1597 c         1492 g         2484 t
ORIGIN      
        1 ttctttttga tttactcaca cttcataaac tttttttgta aaatatttga gaacaagtgg
       61 agaaataagt gtacttaata aaatcacgat aactaaaggt gaatagtact gtggttcgat
      121 caattgactt tgctgtccaa tttgtaaaat gatcaaagcc atttctccac gcgaaatcat
      181 accagcaccg accatcaatg aactatgttg agaaaaaccg gcaatctgag caccaaaata
      241 acctccaagc aatttggtca aaatcgctac aagcgtcaat atagaaataa agagtagttg
      301 ttcactaaag tcagaaaaat caacttctaa tcctacactg acaaaaaata ctggtataaa
      361 tactgcatat cctaaagcct ctacattgtg gtatacttct tctttaacct ttgtctgact
      421 gacagctatc ccagcaaaaa aagcaccaat gacagagcta agcccaacaa gatccgctac
      481 gtaagacatt cctaaacaaa taactagcga tacgatgata atagaagaat ttgcgtacac
      541 tttttctgca aatgaaagta ggaaaggcgc aatccatttg actaataaga aaataaaaac
      601 aaaataaatt agctgttcaa tcaaaacaag cggtaaagaa gcattgctag aagcttcccc
      661 cgttagaaaa gataggctga aacttagaac taaaacgact aaaatgtcat ctaccacaga
      721 agcacccaaa attgttgatc cttcttttgt attcactacg tttagttctt ttaatacttc
      781 tactgaaata ctgacagaag ttgccgcaag aataatccca aagaaaatcg cttcatttcc
      841 cgaaacttgg aatgctttgc ctgtcaacca gccaaaaaca accgggaaga tgatcccaag
      901 caaagcaacg aacataccag gtcggaaata ttttttcaaa agagataaat cactttccag
      961 accagctaaa aacattaata agaacacacc aatctccgaa aagtcatgga ctagaatatc
     1021 aggtttgacc caattcaatc cagcttggcc tagcaaaaca ccaacaagta attgtccaat
     1081 cactgctggg atacctaatc tccgcgagat atgtgagcca atcgttgttg aaatcaatat
     1141 caggcataaa ataccaataa attccattct catcattcct ttgtataaaa tatagcccga
     1201 acttagcata acatacatta ttgaaaaaat aggaaaatat actcacaaaa aaaccaacaa
     1261 tccaaaagat ttttttggat tgttggtttt tatacggtct attttaataa ctaaaaatga
     1321 ttaacgtata gtcatttttc ttattctgat gaaattgata atctcctgga tgcccatgaa
     1381 aatcaaaata aagccgaata tttggaatag aagcatcaaa cttttgaatg gattgaacaa
     1441 taagacgaat ccgccaatca acaacagaat actactataa acactccaac ttttagcttt
     1501 tgtattcatg ctgaagaaca actggaacaa gctgttgatg ataacagcta atccaagaag
     1561 aatcggcagg atagaaacga ttgcaggtgc aaaagcatag acgatcagag ctaagatcag
     1621 gaaaaaaaga ccactgaaca gaccgatact ccaagaacct gttttccttt taaaacggta
     1681 agcctcaaaa agattcaaca acccaagcaa aacaagatag gcggtgatca gataaccgat
     1741 aaaatgaaaa acagcagaag ggtttagcac aatcgcaatc ccagaaataa tataaacagc
     1801 agctcttaat aaggcgtatt tttgaatatt ttgtttaatc gtctcaaaca tataagaaaa
     1861 cctcctttga cttattttaa cgtgaactag tcattttacc aaattaaatg ttacaaaatg
     1921 agcgaaggag aagaatatct ctggaaaaat caacttctga ggatcttttc catttttttg
     1981 ccttttgcta gctcatcgat cattttatct aaataacgaa tttctttcat caagttatcc
     2041 tcgatgtctt ctactcgtac accacaaaca acacctgtaa tcaaggaacg tgaaggattg
     2101 gggacagggg cttccgcaaa aaattgttcg aaagtcactt gtttttgtag ttgatattct
     2161 agttctgttt gggaataacc cgtcagccaa caaatgattt catctacttc ctcttttata
     2221 cgatcttttc tctccgcttt tgctacatac ataggataaa cgcttgcaaa acttgtcgta
     2281 aaaatacgat tttgcgccat aatcagtcac ctttcttttt ttcaaattat ttactactta
     2341 tagtatataa gaaaaagaga agaaaaagcg attattcaaa aaaacaaaaa ggattgtgac
     2401 aaaattcttg tcaccatcct tttttccgct ctctgacttt ttacaatctt catagctcaa
     2461 gtgcgcatca gataatcgaa tgctcctaaa gctgcagtag ctcctgaacc cattgaaaca
     2521 atgatttgtt tgtatggact atctgtacaa tcaccagctg cgaaaacgcc ggggatattc
     2581 gttgcgccat ttttctcggt cactatttca tttcttggat tcatttcgat cgttccatct
     2641 agccaatccg tattagggag taagccgact agaatgaata ctcctgaaac agctagtgta
     2701 tgcatctcca tcgtacggcg atcgatatag gagagagatt ctacctgatt cgtaccgctg
     2761 atttctttcg tcgctgcatg tttgataaca gtgacattcg caagagagac tagtttatcc
     2821 tgtaagattt gatctgcttt taattctggt aagaattcta gaacatatac atgttttgct
     2881 aacccagcca aatcgattgc tgcttcaaca ccagaattac caccaccgat aacagcaatc
     2941 tcttttcctt taaataaagg gccgtcacag tgtgggcaat aagcaattcc tttattttta
     3001 aactcttttt cgcctggtac attgatagaa cgccagtgcg cacctgtcgc gatgatggcg
     3061 gtttttgctt taagtgatat accgttagct aagccaatat taataaaatg ttgctcttta
     3121 tttaaggaaa cggcctgttg attcatcata atgtcgatag ggtaactacg cacatgactt
     3181 tctacttgct gcatcaattt tggaccttct gtgtaagagg taccaatcat attttcaatc
     3241 cctagtgttt caacgacttg tccgccgaaa gaatcagcga caagtcctgt acggattcct
     3301 ttacgtgctg catagatagc tgcactacta gctgctggtc caccgccaat cactaataca
     3361 tcataaggtt ctttttcaaa caactcttct tcaatcaaag ggccagtgat tttttcaaca
     3421 atttgttcga tcgtcatgcg tccgctacta aattcttctc catttaaaaa cacagttggc
     3481 actgccatga tttttttatc atcgatttct ttttggaaca tcccaccttc aatcatcgta
     3541 tgagtaatat ttggatttaa tacagctaat atattcaatg cctgtacaac gtcggggcaa
     3601 ttatgacaag tcaagctaac ataactgtca aaatgcaatg tttgtgttat ttttttgatt
     3661 ttaagactca aagattcact gattttcggt gcccgtccac taatttgtaa catagccagt
     3721 aaaaaagagg aaaattcatg accgaggggg ataccagcaa aaacgattcc actttctttg
     3781 ccaactggat tgatagaaaa actaggtgtg cgcatcgaat ctcttttttc ccaagagatt
     3841 ttaggagaca tttctgctat ttccttcgta aattcagcta gtttttgact attttcacta
     3901 ttatccaaac taacagaaaa aacaatagga gattcaatca gtgctaaata ttgttcgaga
     3961 ttttgtttag tttctttgtc taacatatcc accacctaaa tctttccaac aagatcaaaa
     4021 cttggtttca atgtttcgcc actttctttc cattttgccg gacaaacttc acctgggtgg
     4081 gtacgtacat attgagcagc gcgaatctta tcaatcagtg cactagcgtc acgaccgatt
     4141 ccatctgcat tgatttccat agcttgaacg attccgtctg gatcaataat aaatgttcct
     4201 cgctgagcta atccttgctc ttcatccaaa acatcaaaaa tacgagaaat ctgatgagac
     4261 ggatcaccga tcatcacgta ttcgatttta ccgatagcat ctgatgtatc atgccatgct
     4321 ttgtgagtaa agtgggtatc ggtagagcaa gaaaagactt caacacctaa agatttcaat
     4381 gtactgtatt gttcttgtaa gtcttctaat tcagtaggac aaacaaaagt aaaatcagct
     4441 ggatagaagc aaagaatact ccagttcccc ataagatctt tttcactgac ttctaaaaat
     4501 tctccttgat gataagcatg tgcattaaat tcttcgattt ttttcccaat caatgacata
     4561 gtaaaacctc caacaataat tatttattta taattattgt aatttagttg gagttgcaaa
     4621 gtcaatggat attttgttat ttaataaaga ttactcaaaa acgaaggtta attataaaaa
     4681 tagaagaggt cgcaagaaaa tgctactgct ggaaatactc gggataacgt tgagtaacag
     4741 tttcctgttc tttcagcatc atgtgtaagt gcaatcccgt ttgaaatcga gcttcttctg
     4801 gttttttatc aactaaagcc ttgagtaaat cataatgttg ttccatgatc gtttcccatg
     4861 gaagcccctg aatggtcact cgtaaccagc ggaaacgttc taaatgggta ttatggtcat
     4921 ctaaccagtt ccaaacttct tttcttcctg caatttcgaa acaagcttca tgaaataaat
     4981 tatctgcacg gaaaaaagcg cgttcgtcat ttattttgac tgctttttct tgttcttcta
     5041 aaatcgtttc tagcactatt cgtgtttgtg tgtccaattt ggaacaacat tcaatcatga
     5101 tttgctcttc caactgttct cggacaaagc gagcattttc tgcagaaaca agattaattt
     5161 ttgaaacata cgtaccactt tgaggtatcg tatacacgag ttcttgctga cgtagttgaa
     5221 tcaatgcttc gcgaatggga gtccggccga tagcaagatg ttcctccagt gccttttcag
     5281 atattttcct tccaggttct aagtcagcat agataatttg tttacgaatc gcttgataag
     5341 cttgagattg caagctgctt ttcatcttta ttcctccaaa atcatttcta tgaacgtagt
     5401 ataacagaag aggtctgaaa aacaatctgg tatgtcacat taactagtaa atttgtataa
     5461 atagtaaaat tttggttgac atagcgattt ttattgcata aaattcactt gaatacaaaa
     5521 actaatatgt tagtttagga ggggaaaaat gattgattta aacaactgga ggaactttat
     5581 ccctgaatta tctcaaaaag aagtagaaat acctcatttt gaccgtgcat cattaagaga
     5641 aaatggacaa aaaaatcctg tctggatcca tttcggtggc ggaaatcttt atcgaggatt
     5701 tcatgcagaa atcgctcaac gtttagcgga tctaggcgaa ttgtccactg gtgtcattgt
     5761 ttgtgaaaca ttcgatgaag aaataattga aagggcttac caagattttg atgatttgat
     5821 tcttgaagtg gtcatgccaa gcagtggaga gttcgtcaaa cgtatattag ctgcgacagc
     5881 tgacagtctg tattgtcatc cagattgttc tgaacacttt gataagatga ttcgacactt
     5941 tgaaaatcct agtttacaat tagttacttt tgctattact gaaaaaggtt atcgattgaa
     6001 agatacaaat aataaatata taggaccgat tgcagtcgat ataaaaaatg gtccaaagaa
     6061 gccatcacat acaatgagta ttcttgctgc gctactttat aaacgttttt tatctggagc
     6121 ttggccgatt gcacttgtct ctacagataa tttttcacaa aacggtagtc aattacgtac
     6181 ttctttgcta acgatcgcaa aagaatggca aaaggaaggt tatgtacaaa atacatttat
     6241 ccaatactta tcgaatgaag aaattgttgc gtttccatgg acgatgattg atcgtatcac
     6301 cccgaatcct tccttgtcag ttagcaaaat gttggcaaaa gagggctttt caaatatgtc
     6361 gattttccaa accgcaaaag gaaataatat tgctccattt gtcaatacag aggacatcca
     6421 ttatttaatc atggaagatc attttcccaa tggacgtccg aaattcgaaa aagctggagt
     6481 attcttgact gatcgtgcaa cggtagataa agcagatacg atgaaggtga cgacttgcct
     6541 taatcctttg catacgtctt tagctattat gggttgttta ctggggtata ggagcatagc
     6601 tgaggagatg aaagatccag atttatcgct gctagtttct gaaatcgggt acaatgaagg
     6661 cctcccagtt gtggagtctc caggtatcat tgatccaaag atctttctgg aagaagtaat
     6721 tactgtgcgc ttttctaatc caaatattcc tgatatgcct cagcgaatcg ccacggatac
     6781 ctctcaaaag gtggcgattc gttatggtga gacgattaaa aaatatatgg aaatagaagt
     6841 taaagacccg cagacacttg tattcatacc attgactctc gctgcttggc ttcgatacct
     6901 tattggcatt gatgatcaag gaaaaccatt catcccgagt ccagacccac tattgacaga
     6961 ctttcagcat aagctttccg atattcaact gggtacgcaa gatacatcac atattcatga
     7021 gaaaatggct cctattttgt caaataaaga aatttttggt gtagatcttt accaagcaga
     7081 gcttggcaga aaaatagaag aaatgttcat caagatggta gcaggaccga atgccgtacg
     7141 aaaaacatta caggattact tacaagaaca tggaggaaat ttatcatgga aatgactttt
     7201 agatggtacg gatcacagga agaaaagatt accttagatg aaatcagaca gattcctgcg
     7261 gtcaaaggga ttgtaggcac attgatggat ataccagtag gagaggtatg gcctagggag
     7321 aggatcaaag aactaaaaga agaaattgag tctcgtgggt taacactaaa agtaattgaa
     7381 agcgtcaatg tgcatgatgc cattaaaatt ggattacctt cccgtgagca gtatatcgaa
     7441 aactataagc agacaatccg aaacttggca gaatatggaa tagaagtcat ctgctataat
     7501 tttatgcctg tatttgactg ggtgaaatct gaccttgact accgcttaga agacggctca
     7561 tccacgttag cttttatatc tgatgatatt ccagatgatc caagagaaat cgtcgcgcgc
     7621 atcgaacatt ccagcaatga atttgaattg ccgggatggg aacctgagcg cttagctcat
     7681 atcaaatcct tgcttgaagc ctatgcatca gtagacgaag aaaaacttcg agaaaatttt
     7741 gcctattttc tccaatcaat catcccaaca tgtgaagagg taggggtcaa aatggctgta
     7801 catccagatg atccgccata ctcgattttt ggattacctc gaatcgtaaa gaatcgagaa
     7861 gatttagatt ggttgtgccg catagtagac agcccttata acggaatcac tctttgtaca
     7921 gggagtattg cagaagatcc agaaaatgat gtatatggga ttttagcaga attttgtcaa
     7981 agagatcgaa tcccatttgc acatgttcga aatattaaat ttttagctaa tcgagatttc
     8041 tatgaggcac cgcataaatc cgaatacggt tcattagaca tgtaccgcat actaaaaaca
     8101 atgtatgaca acggatttaa cggatacatc cgtcctgatc atggaagaat gatctggaat
     8161 gagacaggaa gaccaggata cggcttatat gatcgagcat taggtgctgt ttatctaaat
     8221 ggattatggg aagcaatcga aaaaggaaac aaaagtaaag ataattagtg aaaaaaactg
     8281 taattttatt atgtaaataa gaaggatgtt caaattc
//
LOCUS       DAIGWC010000097         8057 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.100, whole genome shotgun sequence.
ACCESSION   DAIGWC010000097 DAIGWC010000000
VERSION     DAIGWC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8057
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.100"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..148
                     /locus_tag="NOB74_002525"
     CDS             <1..148
                     /locus_tag="NOB74_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI1221663.1"
                     /translation="EKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRY
                     SLGY"
     gene            complement(303..746)
                     /locus_tag="NOB74_002526"
     CDS             complement(303..746)
                     /locus_tag="NOB74_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221664.1"
                     /translation="MEAYEFLGAALRNIFGNLLSACLVAEYLVKRKIVRFNNIFVIMA
                     SIVGIGFAGISKIIGGLMESINDIFAFFGYGAIAILMYQVIPFRKIMPRISRYSYDIY
                     LLHILVFSTIHQIIPNLVLAAFVSIPITLVLSYYYSIMLYRLKLK"
     gene            complement(834..1199)
                     /locus_tag="NOB74_002527"
     CDS             complement(834..1199)
                     /locus_tag="NOB74_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HCI1221665.1"
                     /translation="MYYFQQSYLPAILNKAISIGDTGVHIFFFCSGFGLYLSYLKKPI
                     TLGEFLQKRFIKIYIPYIIVITVSVLLPYMTQDLNAAKVYLSHVLLFKIFLPVYEESL
                     GPFGLFRQLFSSISYSYQL"
     gene            complement(1543..3195)
                     /locus_tag="NOB74_002528"
     CDS             complement(1543..3195)
                     /locus_tag="NOB74_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCI1221666.1"
                     /translation="MDHNANYYHWLTNANAEIVEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLSDYLNKTYETPSVVVGYDSRIKSDVFAKVAADIF
                     AANGIQVHLWPELLPVPTVSFAIRYLKASAGVMITASHNPSKYNGYKVYGAGGCQITT
                     EAAAEILAEIEKLDIFADVKMGGDASRIASIQPEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEINEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKNAEGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PTDPVMVKTIVTMDLGERIASNYGVRTVDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLFDKLNEIYAKYGYCLNTLHSF
                     EFEGAAGFTKMQKIMVEFHKGLDMIGGKKVIETLDYSTGLNGLPKSDVLKYLLEGNCS
                     VVVRPSGTEPKLKTYISVSAESKEAAEVMEAVMAAELAEMFK"
     gene            complement(3255..3834)
                     /locus_tag="NOB74_002529"
                     /pseudo
     CDS             complement(3255..3834)
                     /locus_tag="NOB74_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
     gene            complement(5066..5782)
                     /locus_tag="NOB74_002530"
     CDS             complement(5066..5782)
                     /locus_tag="NOB74_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI1221667.1"
                     /translation="MTVIITMAGLGSRFRKVGYTVPKFMIEAKGKTLFDWSLDSLLDY
                     NSHVEKYVFVVRKEDDATVFIKEHCSLYGIENVEVVEIDYMTDGQATTCMLAIPYCAP
                     DNAIMVYNIDTYVEPGEMKYVDISGEGHIPCFHADGDHWSFAKLNEYGDVVEVREKVR
                     ISNNCTLGAYYFSSAKLYASLYEEYYADERHLEKNEKYIAPLYNYMIEKGMKVTISIV
                     DKSKVHVLGTPEELDVFLNE"
     gene            complement(5807..6205)
                     /locus_tag="NOB74_002531"
     CDS             complement(5807..6205)
                     /locus_tag="NOB74_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HCI1221668.1"
                     /translation="MFKDYAFVFDIDGTLCPIKKKDEKYEDLVPYANMVEKLRYYKEN
                     GAKITLFTSRNMNSYHGNLGVINANTAKILLAWLDKWEIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLSCTLDQLDEICKKSKLKSE"
     gene            complement(6293..7933)
                     /locus_tag="NOB74_002532"
     CDS             complement(6293..7933)
                     /locus_tag="NOB74_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HCI1221669.1"
                     /translation="MRLLIPSAKIVPEELHHLGKLPAIIYPINQKIVFDYLYDQYKDV
                     CSAIDIACYEKMDKVARRLDKYIKSKTVNIIQLKELGDLGRTIYDSLIGCDEPVIINF
                     ADTIINDNIYSLECDSFFYAEDYYSNTWTFFEEKDGDIISVLDKNELKEDDGKKHKLF
                     SGVFQIMDAQYFRECLRKALMSNVVNVNSFYQALQEYSKRYEFLSIKTNNWFDIGHAD
                     KYYNSKLEVKAREFNHISIDKDRSILRKISEDVEKFIGEIKWYLKLPAQVEYVRPRIF
                     EYSTSYINPYVSMEYYSYHTVHELFLYSDLTKKQWIDIFNRIRFVCSDFKRYSVSGDN
                     IQKSLKDMYLDKTFQRFNKLRKDPRFTEFFSSDIQINGVRYKSLDQIEALLSVSVPRE
                     LFDITQFNIIHGDLCFANIMVDNTFSFIKVIDPRGKFGDFDIYGDYRYELAKLFHSVD
                     GKYDFIIKDLFTIKYDPKKAIIDYIVQDRKRDYDLYEVFYSVFKDEIGSDLKKIELIE
                     ALLFLSMIPLHGESLNHQMAMLATGLEILGRVVPDIYC"
BASE COUNT         2702 a         1700 c         1187 g         2468 t
ORIGIN      
        1 agaaaaatta ggttgtcaaa atttcaactc acgttctgtt aaagggctag agagtagatt
       61 tgaaagcata ttactggctt acagtgttct attaagtcga gcacaacgac gttttgaagg
      121 aactttgaga tattctttag gatattaaaa ttaactagca ccacgggtgt aatcatttag
      181 ttttatctcc tttttaccaa ccatctacca ctaggttacg aactacctaa gtgcccacca
      241 tccgccgcgt ggaggctgtt aatcaggatg gcaaccgccc ggtagaggcg acaattatgc
      301 tatcatttta atttaagtct atataacata atactataat aatatgacaa caccaacgtt
      361 ataggaatgg aaacaaatgc cgccaaaacc aagttaggga taatttgatg aatcgtacta
      421 aatacaagaa tatggagtag atatatatca tatgagtatc ttgaaatcct aggcattatc
      481 tttctaaatg gaataacttg atacattaaa attgcaattg caccgtaacc gaagaatgca
      541 aaaatatcat taatagactc catcagtcca ccaataattt tcgatatacc agcaaaacca
      601 attccaacaa tggacgccat aatcacgaat atattattaa atcttactat ttttcttttc
      661 actaaatact ctgcaaccaa acatgccgaa agtaaattcc caaatatatt gcgcaaagca
      721 gctcccaaga actcgtatgc ttccatatcc tgtatgaaac atcataatag cccagatact
      781 aataactcag cttgcaacaa gcaatcattt cattcctatt tttctctata gttttacaat
      841 tggtatgaat aagaaataga actgaataat tgtcgaaata aaccaaaggg acccagtgac
      901 tcctcatata ctggtagaaa aattttaaat aacaaaacat gagacaaata tacttttgca
      961 gcatttaaat cttgtgtcat ataaggtagt aacactgata ccgtaattac gataatatac
     1021 ggaatataaa tcttgataaa tcgtttctgt aaaaattcac ccaatgtaat aggctttttt
     1081 aaatatgaca gatatagccc aaaacctgag caaaagaaga atatatgcac tcctgtatca
     1141 ccaatagata ttgctttgtt cagtattgct ggcaaatacg attgctgaaa atagtacatc
     1201 aatacaatag cgaatattga aaacgccttc tcaaaactaa taatatcacg tttatttctt
     1261 tccccctcat tttattattt caatagtttt attcatattc tactcctttc atctctattg
     1321 ctgaatacat tattaaaact ctaatatctc ttatttctcc cttactgctt tgatcggtgc
     1381 ttcatcaggc tgctgtgtct ctgttaacac ttctttgcct tttcgatcca cacagtcggc
     1441 ccctttacct caattatgta aacagaaccg taaagcagga aatttttatt aaacatagat
     1501 gttgctactt cggacattga cactcagatc tttttcatag tattacttaa acatttcagc
     1561 cagttcagca gccataacag cttccattac ttcggcagct tccttgcttt ctgcgctaac
     1621 gctgatatag gtcttcagct tcggctcagt gccggaaggc cgaaccacta cagagcagtt
     1681 gccctccagc agatatttga gaacatcaga cttcggcagg ccattcagtc ccgtgctgta
     1741 atccaaggtt tcgatgacct tcttacctcc aatcatatca agacctttat ggaattcaac
     1801 cataattttc tgcatcttgg taaaacctgc cgcaccctca aactcaaagg aatgcagggt
     1861 gttcaaacag tagccatact tagcataaat ctcgttcagc ttatcaaaca gactgatacc
     1921 ctgagtcttg tagtaagaga acatctcgca gatcagataa gcggcgttga caccatcctt
     1981 gtcacggaca tagctgccgg atagatagcc gtaggattcc tcaaagccga aaatatagct
     2041 gtccaccttg cctgcctttt ccagcatacc aatctgttcg ccgatgaact tgaagccggt
     2101 caacacatcg acagtacgca cgccatagtt ggaagcgatc cgctcgccca gatccatagt
     2161 cacgatggtc ttgaccatca cagggtcagt gggcatcttg ccgtgcttaa ttctctgaga
     2221 gcatatgtag tccagaagca acagaccagt ttcgttaccg gacagcagga cataatcccc
     2281 ttctgcattc ttcacggcga tacccacacg gtcgcagtca gggtcggtag ccagcagcag
     2341 atcagcatta tacttcttgg catactccat gcccagagac atagcttcat taatttccgg
     2401 attcggataa ggacaggtcg ggaaattacc gtctggcaga cgctgctctt cgacaacggt
     2461 cacattgctg tagcccattt ctgccagagt acgggtaaca ggcaccagac cggtaccatt
     2521 caaaggagaa tacacgatag caacattctt gtccacttct tcgccaaaca gaaccgactg
     2581 gccctttact tcttcaatga aagcagtcag aacctctggc tggatagaag cgattctgga
     2641 agcgtcgccg cccattttca catctgcaaa aatatccagc ttttcaattt cagccagaat
     2701 ctcagcggca gcctcggtgg tgatctggca gccgcctgcg ccatagacct tatatccgtt
     2761 atacttggaa ggattatggg atgcggtgat cataacaccg gcagaagcct tcagataacg
     2821 gatagcaaag gatacggtag gcacaggcag cagctccggc cacagatgca cctgaatacc
     2881 gtttgcagca aagatgtccg cggcaacctt tgcaaataca tcggacttga ttcgggaatc
     2941 atagcccacg acgacagaag gggtttcata ggtcttattc agatagtctg acagtccctg
     3001 gcttgcctta cctacggtgt gtacgttcat acgattagtg cctgcaccaa tggtgccacg
     3061 cagaccaccg gtaccaaagg acagattttt atagaaggag tcctcaatgt ccttctcgga
     3121 atatgaccgc agttcctcta caatttctgc attggcattt gtaagccaat gataataatt
     3181 tgcattatga tccatagaat ctctccaatc ttttaaaatt ctgctcattt atttttaagg
     3241 ttaggatgaa tatatcagct caaataatat ataaccccac taatgccgcc acccaaagta
     3301 ttataaaata aatctgacaa ttggaatgtc tctatgtgta aaaataactg caaaaactct
     3361 ataagacacg aacataaaaa aacaaatttt ataatctctg ataaattttt ccaaaatctt
     3421 tttctgaagc cttataccac attactagaa ttataaatgg aataaacaga ataacatttt
     3481 caaaacattc tgtagttaat ctaatctccc ctgtcgtttc attcacagag taaatccacc
     3541 aactaccaaa cacattagac aaaggattta gccaaacata tctatccatc agtgttctaa
     3601 aaagaatcat atttgtaaaa aacacaagca aaaacatttt tctaaatgag cttgattttc
     3661 tgaaataccg aatccagaca agaaaagatt ttttcaaacc taatcctgat ttctcctcag
     3721 ccatcgcaaa caagtataaa aacatagcca aaactgcaat taaaatcgaa acccaaatat
     3781 ttgatacaat gcagataaca cattaaccaa aatagaagat atgattttct tcataaactc
     3841 tcctttcatc atgcgctaaa tgagtaccat caagaaggtt tcgtaaaagg aggtacccac
     3901 tctaacatga ataacctcgg ccagcgaaaa taaaactcaa cagaattcct atctctatgc
     3961 tgctataatt tcaacaaatt tacatgtacc agttactaat ctaatataat tttttcagca
     4021 aggtaaattt cacactacac gcatacacaa aaactgtaga aattaaaatt attatcattc
     4081 cacaagtcat ttctattaat gaatttgtaa tccccaattt tgggaaaata aaatttaaag
     4141 cagctattat atacggatgt aaacaaaata ataacgtact aattcttcgc agatgtactg
     4201 ttatttttat aaatgtacta tctttaggct cagtgatact gatacaacta ccagtgctaa
     4261 tggaatggaa aatattaaca aattattgac ttctcgcaaa gctatttgat ttatgatgaa
     4321 actttcacca actaataagc atcctatagc taaaacagca cataagataa aattacggta
     4381 tttaaagacc ttattaagta tagtgttttt gtggaaggct aagtgttgcc caataatgac
     4441 gcatggtaca cctataaata atccattacg agttgttaca aacacgcttt tataacaata
     4501 tctaatatac tcgatggaat cattcccaga taatataaac caataagatt caaatgctaa
     4561 acctactacg catagcaaca aaccactgag aaactttatt ttagaaacct ggcttttgcg
     4621 tactaaccat agagcaaaag ccagtgcagg caagaaccac aggtgatagt aactaccaat
     4681 aaacagaaaa tctctgatat acaataatac atctgttttc cagctaaaat ctgactgtac
     4741 ccaattcttt aatactaatg gaatatataa tatagaccaa ataatgtaaa ttttaagtac
     4801 tctgtagatt tgtttagata atttagcgga tgtaacttca ccactacaca acaaaaagga
     4861 actgatgatg aaaaaagtag gaacggcaac cgtactcagt cctgcaacaa taccaatact
     4921 aaatgcttaa tctggagcta aatagttttg acctaaatga cgaacaacaa ctaaaatagc
     4981 cattagtatt tttagaatat ctatcgaata gtactccccc acacacgcag ctttataatt
     5041 aacattttct atgattatat tttccctatt catttaagaa cacatcgagc tcttctggag
     5101 taccgagtac gtgaactttt gatttatcta ctatactaat ggttaccttc atgcccttct
     5161 ctatcatata attatatagc ggcgcaatat atttctcatt cttttccaga tgcctttcat
     5221 ctgcataata ttcttcgtag agtgatgcat ataattttgc agaagaaaaa taatatgcac
     5281 ctaaagtaca attgttagaa attctaactt tttctcttac ttctactaca tcaccatatt
     5341 cgttcaactt ggcaaaactc caatgatcac cgtccgcatg gaaacacgga atatgtcctt
     5401 ctccagaaat atcaacgtat ttcatctcac ctggctcaac atatgtatct atgttataaa
     5461 ccataattgc attatcaggt gcgcaataag gaattgcaag catacatgta gtggcttgtc
     5521 catcagtcat atagtcaatt tcaactacct cgacattttc aattccatac agactgcaat
     5581 gttctttgat aaaaacagta gcatcatctt ccttacgcac aacaaaaaca tacttttcta
     5641 catgtgaatt ataatcaagc aagctgtcta aggaccaatc aaataaggtt ttaccttttg
     5701 cttcaatcat aaatttgggc acagtgtagc caactttacg aaagcgactg ccaagaccag
     5761 ccattgtaat aataaccgtc atcttattca ctttataaag tctcctttac tcagatttca
     5821 atttggattt tttgcaaatc tcatcgagct gatccagggt acacgataaa aattcatccg
     5881 gacgaactgt gcgatcatca acataaaacc ctttatggcc tggccaaggc tttccataaa
     5941 gaatttcatc atacggaatc tcccacttat ctagccaagc caacaagatt tttgcagtat
     6001 ttgcattgat cacacctaaa ttaccatgat aagaattcat attgcgagat gtgaacagtg
     6061 taatctttgc tccgttctcc ttatagtatc gcaacttctc caccatatta gcatacggaa
     6121 ctaaatcttc atatttctca tctttctttt tgatggggca caaagttcca tcaatatcaa
     6181 aaacaaatgc gtaatcttta aacatataac taagacatct cctttatttt agccaggcaa
     6241 tttatatgcc cggctttaca ctgatcaaat agaaaaacaa tagctcaaag cattaacaat
     6301 aaatatccgg gacaactcgt cctaaaattt ccaaaccagt tgctaacata gccatctgat
     6361 ggtttaagct ttctccatgc aaaggaatca tacttaaaaa cagcaaagcc tcaataagtt
     6421 caattttttt caaatcagaa cctatttcat ctttgaagac agagtaaaat acttcatata
     6481 aatcataatc tcgtttacga tcttgaacaa tatagtctat gattgccttc tttggatcat
     6541 attttattgt aaacaagtcc ttaattataa agtcatattt tccatcaaca ctatgaaaca
     6601 attttgccag ttcatatcta taatcaccat aaatatcaaa atctccaaac ttacctcgcg
     6661 gatctatgac tttaatgaac gaaaatgtgt tatctaccat aatattggca aagcataagt
     6721 caccatgaat aatattaaat tgcgtaatgt caaacaattc tcttggaaca cttacgctca
     6781 ataaagcttc tatctggtcc aaagatttat atctgactcc atttatttga atatcagaag
     6841 aaaagaattc tgtgaaccgg gggtcctttc tgagcttatt gaatctctga aatgttttat
     6901 cgagatacat atctttcaat gacttttgaa tattatcccc tgaaacagag tatctcttaa
     6961 agtctgagca tacaaatcgt attctattaa agatatctat ccattgtttt tttgttaagt
     7021 cactatagag aaataactcg tgaacagtat gatacgaata gtattccata cttacatatg
     7081 gattaatata cgaagtagaa tattcgaata ttctaggtct cacatattct acctgtgctg
     7141 gcaacttaag ataccactta atttctccga taaatttttc aacatcttca ctaatttttc
     7201 tcaggatgct acgatcttta tcaattgaaa tgtggttaaa ttctcttgcc ttaacttcca
     7261 atttggaatt ataatattta tctgcatgtc caatgtcaaa ccaattattt gttttaatag
     7321 agagaaattc atatcgtttg ctatactctt gtaaagcttg ataaaaacta ttcacattta
     7381 ctacatttga catcaaagct ttacgcaaac actctctaaa atactgggca tccataattt
     7441 gaaatacacc agaaaacagt ttgtgcttct ttccatcatc ttcttttaac tcgttcttat
     7501 ctaaaacaga aataatatct ccgtcttttt cttcaaagaa tgtccaagta ttactataat
     7561 agtcttcagc atagaaaaag ctgtcacatt ccaaggaata tatattatca ttgataatgg
     7621 tatcagcaaa attaataata acaggctcgt cacatcctat tagagaatca tatatagttc
     7681 ttccaagatc ccctaactct ttaagctgaa taatatttac tgttttagat ttaatatact
     7741 tatctaatcg tcttgctacc ttatccatct tttcgtaaca ggcaatatcg atagcagaac
     7801 atacatcttt atattgatca tataaataat caaatacaat tttttgatta atcggataga
     7861 taattgcagg aagttttcca agatggtgaa gttcttccgg tacaatctta gcagatggaa
     7921 tcaataatct catttcaccg tgcctccgtt ccattcccaa gatttgcttg ttaatttttt
     7981 atatttttaa ggattttcat tatttgcgtc cttttaagaa aagccacaat aactaatcca
     8041 ataataatac tatatct
//
LOCUS       DAIGWC010000098         7625 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.101, whole genome shotgun sequence.
ACCESSION   DAIGWC010000098 DAIGWC010000000
VERSION     DAIGWC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.101"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(14..706)
                     /locus_tag="NOB74_002533"
     CDS             complement(14..706)
                     /locus_tag="NOB74_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI1221670.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1143..1712)
                     /locus_tag="NOB74_002534"
     CDS             complement(1143..1712)
                     /locus_tag="NOB74_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI1221671.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="NOB74_002535"
     CDS             complement(1786..2109)
                     /locus_tag="NOB74_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221672.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="NOB74_002536"
     CDS             complement(2263..3075)
                     /locus_tag="NOB74_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221673.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="NOB74_002537"
     CDS             3429..4277
                     /locus_tag="NOB74_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HCI1221674.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4422..5363
                     /locus_tag="NOB74_002538"
     CDS             4422..5363
                     /locus_tag="NOB74_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HCI1221675.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="NOB74_002539"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="NOB74_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2272 a         1512 c         1371 g         2470 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acctatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtgtgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatctc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggttcg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaaa
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag ttacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgagaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgaa tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagctttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaacgg tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tcgaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aacct
//
LOCUS       DAIGWC010000099         7597 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.102, whole genome shotgun sequence.
ACCESSION   DAIGWC010000099 DAIGWC010000000
VERSION     DAIGWC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.102"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(940..1353)
                     /locus_tag="NOB74_002540"
     CDS             complement(940..1353)
                     /locus_tag="NOB74_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HCI1221676.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1809..2294)
                     /locus_tag="NOB74_002541"
     CDS             complement(1809..2294)
                     /locus_tag="NOB74_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221677.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2433..2648)
                     /locus_tag="NOB74_002542"
     CDS             complement(2433..2648)
                     /locus_tag="NOB74_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HCI1221678.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2872..3672
                     /locus_tag="NOB74_002543"
     CDS             2872..3672
                     /locus_tag="NOB74_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1221679.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3691..5559
                     /locus_tag="NOB74_002544"
     CDS             3691..5559
                     /locus_tag="NOB74_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCI1221680.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5552..6043
                     /locus_tag="NOB74_002545"
     CDS             5552..6043
                     /locus_tag="NOB74_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCI1221681.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6031..6585
                     /gene="srlA"
                     /locus_tag="NOB74_002546"
     CDS             6031..6585
                     /gene="srlA"
                     /locus_tag="NOB74_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HCI1221682.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6603..>7597
                     /locus_tag="NOB74_002547"
     CDS             6603..>7597
                     /locus_tag="NOB74_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HCI1221683.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2234 t
ORIGIN      
        1 gttactatga ataacataat aagaaagtaa agtggattga tttgagatct ttttatactt
       61 caaaaaagat aacacccaac tttcaaaaat atgttttgga agttgggaca aacgagttaa
      121 tacattttaa tacattattt tttattcaaa aaaaatagca caatggcaaa gatcgtaaga
      181 gagatcataa gccccaatga atgactaaaa agaaaagcag aatcacatgc catatcatcc
      241 catatttctt caagaaaata aataagcggg aaaaagggaa ggaatagtag aacatcgatc
      301 cagcaccatt tttttcttct tttgaaataa cataaaacaa taaacatgaa cgtgcaggga
      361 agtaaaaaca aagctttact cataactaac aaaataccag ctccttttat ttttttctcc
      421 cccacattca aagagtaaca atggtatgta cttaataata gaaaaatgga tcaacttgta
      481 tgaataacag ctgaaaagat ctgcaccaaa taaaaaactt ccagccaaaa ctgactggaa
      541 gtttattttt ttctgaaata ttctaacaca aatatgaaaa agatggccga agctaataag
      601 ccgatttcgt agcaaaacaa tgagatacca gagtcgtaat aataaaatcc tctaatctta
      661 tggataaaat agatcatcgg acaagcagat aagagtaagt atttgttagg ccttttgaat
      721 aagtaaaaga aagcactggt cattatgata aatggtatcc aaaacaaaag tttacttaag
      781 acaatcaaat gatcaactcc catatttttt accaagagag atcataacat ctttatcgta
      841 aaaacaaaat atttttttgc tcattttgaa aatttaaaca tactcgttct tatccaaata
      901 tataaaaatc gcccctcatt catcgagagg cgataagttc taatttaact caattttttt
      961 tgtttctttt ggctgataag ctgttttagg taataccaat ttcagcacac cgtttttaaa
     1021 ggttccagtg attttttctt catcaacatt aggaagatag aatgaacgtt tgtaagagac
     1081 cgaatgtctt tctttccgta catagttgcc atcttcttta tcttctgtat gggactcatg
     1141 attggcggag atcgtcaaag tattatctga atattcaact gtcgtgtctt ctttgtcaca
     1201 gccaggcata tcagcagtta gtttgtattc tttttcattt tcgactaaat ctacttttgg
     1261 ataacttgaa acacctaaaa aatcattgaa tgctggacta aacacgtcat tgaaatcagg
     1321 gaacatgtcg cgaatgctag gtacatttgc catttttgat catcctttca ataagtattt
     1381 tttatttatc cctatttacg taataactct attttgaaaa aaatgcaagt ataatggtta
     1441 gctttgtgaa tatttcatct aatacgatac aaaggctatc tttctaattt gaaaaaggga
     1501 tcattaaaat aataagaaga aaatatgtca aaaggtaaaa aagtaaattc ttctatccaa
     1561 atatagaaaa attgaatcta gaaaaccgcc cgacaataaa tttcattaac tcagttgacc
     1621 gaaaatgaag tagataccaa aaatttatca agagagcaag tagagaagtg agtatattca
     1681 taagagaaat agctgtaacg aattattagg ttaatgcaaa tgcttattta tactccgtat
     1741 aactttctca gaaaaaatga taccaataat gacttgctag tactgtaaat ccgtataata
     1801 tcatctaatc aaaatggtgt tccatttgca tctgtcatcg taatcgatcc ttcgggtgac
     1861 actcgataaa aaccaacgct tccagatcct ccttgggaac ggatttgttt gctggaagct
     1921 gtgaacaaat aatctcgatc aattttttga taaaagctaa taacaatatc gtcactttgt
     1981 aattcggaac ggtgggcaat aagaaataga agtgctttgt cagagttttc taatggaaga
     2041 gaaggtacag tgctttcttg catttcagat gttgaagaaa tgctaaacga ctgaatactt
     2101 gattggctat gttgcgaatc tacattacca gtagaagtat tagtaatgga agtagtagaa
     2161 gtacttttag ttgaaccaac ctcagttgtt gaaatggctg ctgaagattc tttaacagaa
     2221 ttctttgttt tatatccaca ggcagaaaaa agtattacag ttcccaacaa gcctgcgtaa
     2281 atccctttat gcatgatagc tcctcctaaa atagattatc tttattcagt atatcactta
     2341 aacaaagaaa agcagatggt ttaaaatgaa aaaaccttcc caataaaggg aaggttcatg
     2401 aagataataa cttttttaat aattatagct ttctaatatc tttcatcaac ttttctagta
     2461 atcattggga aaaatttcaa gcagtagatc gcacaaatac ctacgacgat ataaatgatc
     2521 ttcgcaaaaa tagttgttga accaccagca atcatagcta ctaaatcaag ttcgaacaag
     2581 cctaccaaca gccagttcaa ccctcccaca atcaataaag ttaatgcaat agcatctaaa
     2641 gttttcatta gaattctcct ttcttaaatg ataaaacaat tatatatcaa aaagagaaac
     2701 attgcttata taacgctcag gaattttagc aatctatgca aaaagatgaa aatttttttt
     2761 gctcttccat tagtacacat tttttagctg aagctgtaaa tttcatgtct taattttttt
     2821 tagtgagctt ttatactgga tttgtaagaa aaaagaagga gaggatcaca tatgtcggat
     2881 tggttggata ttgcaggaaa agtagtaatt gtaactggag gttcctcagg aattggaaga
     2941 agtatcgtcg aaaatttgtt gaagcagaat gcacaagtag cgaattttga tgtaactgaa
     3001 tgccgtatac agcatgaaaa cctactatct ttaaaagtcg atgtgtcttc taaaacggac
     3061 atagaagaag ggatatataa agtaatgaaa catttcaaga cgatcgatgg tctagtcaat
     3121 aatgcaggaa taaatattcc ttctcttcta atagatagaa atcatccaaa aagcaagtat
     3181 gaattatcag aacaagtttt tgataagatg atcgctgtca atcaaaaaag tgtatatttg
     3241 atgagccaag cagttggaag aatcttggtg caaaagggat caggagtgat cgtgaatctt
     3301 tcttctgaat caggattgga aggatcagaa ggacagagct gttatgctgc tacaaaagca
     3361 gcgatgaaca gttttactcg ttcttgggca aaagagttag gaaagaggaa tgttcgtgtg
     3421 gtaggtgttg caccagggat actggaagaa accggtttga gaacacaaga atatgaagaa
     3481 gctctttctt atacgagagg tataagcgtc gaacagctga gaaacggtta cagtcgaaca
     3541 agtacgatcc ctctaggaag gagtggtaag ctgcaagaag tggcggatct agtctgctat
     3601 tatctttcag aaagatcaag ttatatcact ggagtcacga ctaatatttc aggaggtaaa
     3661 acaagaggat aaaggatagg ggggacgcac gtgacgctag taaacagatg gtaccaatta
     3721 ttgaaattac tagtcactca caagaaagtt tcaatccagg aagtgcaaaa agaaatcaaa
     3781 accagtaatc aaaccataaa aaaagatatt ggggagttga atgaagaaat tgccggtatt
     3841 gcaaaaatca tccaaaaaaa caaacatttt gaacttgaaa tttatgattt tgattttttt
     3901 gatgagatca tgcaaggaaa attgaaaaca gccagtgatt tcaattcggc atccaaaaga
     3961 atcgcttatt tactaaatag gctgatcgaa acagaggatt tcttacgtat ggatgatttg
     4021 tctgaagaag tcggtgtcag cagaggaaca gtggtcaagg atctaaagac attaaaagag
     4081 atgatcaatg attttgatgt aaagattaca ggcacaccaa ataaaggact aagaataata
     4141 ggagatgagc tagaattacg actactttta ttttattttg tttctcccta cttttcagag
     4201 acgaaaacag aacagtttct agaagaaaaa caagcaatca aacattttca gaagaagacg
     4261 aatgctagta aacaagaaat caccctttta acgaaagtta tcggtatttc tttgaataga
     4321 atctctagta actatctgtt gaagaagccc atcaatcgtt acagtgggtg ttttgaatat
     4381 atccaagaat tcaatgaact gatcaatcag ttggaagaaa tctatgaact aactttgagc
     4441 caatatgaaa aagattttat cagttttcct ttgaacatca tcaacacaag tataacgatg
     4501 ataaggaaag ctaactctga tttgcgctta tatttcgacc ccatgatgat gcgtattcga
     4561 cgattagatc tcattgatct ggatgagtcc ttcttatatc aagagatgaa acagcacctc
     4621 tctttattga taaatcgggt aatttttcgt tatcgattga ctgatttatt ttatggtgag
     4681 atagaaaaaa agtatccttt ttcttaccaa atcgctagcg aatgcataca agcattagaa
     4741 gctatcttgc aacataagat ctctaaagta gagatcagct acctaacgtt gtatttggag
     4801 ttagcatttc gatatcaaaa agagcatttt tcctctaaaa aagtagccat tgttcatacg
     4861 acaggaaaag gaacagcatt aatgatccaa agacaaatca aaaggatatt ggggagggat
     4921 atacaaataa cacatgtttc agaagaacaa tatgaaaaag tagatctaaa caaatatttc
     4981 gctgttttta caacgattcc gttaaaaaat gtaaatgaag agacaccggt gatccatttg
     5041 actaatcttt ttgatgactc ttggttaagg gcacaatggc aaaaagcaaa aaaaaagcga
     5101 ttagccgggt ttcattctac tgtttttttc tatcaaatat ggaaagaaaa aaagacgtat
     5161 caagaatatt taaacaaatt agtcgctcct ttgatcagag gctattatgt ggatgaagaa
     5221 tttgaaaaaa ggatcttgaa aagagaatat cagcaaagca catttgttaa caaagaattt
     5281 gcttttcctc acacaaccaa ccagctatct caacacattg ttttatcagt agggctaata
     5341 actgatcaag gtttagcaga aacaggagga aatggagtta tttttttatt tgccatacct
     5401 gaagaaatga cggctgaagt tgagaatgaa ttatttgagc tatacgatat cctatttgaa
     5461 ctcataaaaa tgggaataga tgagtttatt gaattagcac cgacacaaga atcattttta
     5521 aaactaatca aaagtaaagg agagagactt catgaatgat atgtatctat tcatagtttt
     5581 cgcagcttca gcttatgtgc tgcaagcagt tatcagttgg aagcaactaa agcatttcaa
     5641 tcaaacatat agcgaactgc gaagaaaagg aaaagtagcg attggtaaac gacctgggaa
     5701 aatccgttca ggcacgattg ttatgctagc tatagacgat catgatcaag ttttagaagt
     5761 cagaaaaatg caaggggtta catctttggc aaaatttcat tcattacctg tctatgcggg
     5821 tgaagatatc cattacatcg atcgttacca tccctcagtt cgagcggaag atcgtttgac
     5881 acaagcagct ttagaaaatg ccagagaagt atacttacga atagaggcag gaaatgaaaa
     5941 aagtgaacaa ccttcattgc cttttattgc tatgctcaat aattttcgga tatggaaaag
     6001 tacgatcaaa gaaaaaagga gtgacaaacg atggatatca taacaaaatt tgctgaggga
     6061 tttatgaggc tgttccaaac aggtgcagaa acattcataa gctggatgac aggaatcgta
     6121 ccagttgtct tgatgctgat ggttgcaatg aatacgctga ttgctttttt aggtgaagac
     6181 cgagtaacga aagtagccaa attatcagcg aaaaatccgc ttactcgtta ccttgtgtta
     6241 ccgttcttat ctgcttttat gttgggaaat cctatgtcat ttacaatggc tcgtttcctt
     6301 ccagaatact acaaaccaag ctattatgct gctcaagctc aattttgtca tacgagcaat
     6361 ggtgtattcc cccatattaa tcctggagaa ttgtttgtat ggatggggat tgctcaaggg
     6421 atcgaaacct tagggctaaa ttcgatggag ctggctatcc gatacttgct tgtgggactg
     6481 ctgatgaact ttattggtgg ttggataact gattttacta ctggatttgt atgcagacag
     6541 caaggaatcg ttcttagcaa aaaagtagag ctttcagttg attagagaaa ggagagtttt
     6601 aaatgtatgg tgatattaag atcgtaagag gaaacggcgg gtatggaggt cctttgatta
     6661 ttaggccgac aaaagataaa cacaagttca tctatgtcac aggtggaggt gagaggccaa
     6721 tgatcgtaga taaaatagaa gaactgacag gtatggagtc tatcaatggg ttcaaaacat
     6781 caatacctga tagtgaaatc gcgcttgcaa tcgttgactg tggagggact cttagatgtg
     6841 gaatttatcc taaaaaaggg ataccaacca tcaatatcgt ttccacagga aaaagtggcc
     6901 cattagcaca atatatcact gaagatattt atgtttcagc agtagggtta gaacaaatac
     6961 agccactaat ggaaactgat gataacaaag aaacagtaaa tactgcatct ccagataaaa
     7021 agtacaaata tgatacttct aaaaagataa ccgagcaaaa agcagagcag caaaactgga
     7081 tagcaaaaat tggaatgggc gcgggaaaag tagttgctac attcaatcaa tcagcaagag
     7141 aagcagtaga tacgatgatc cggacagtga tcccttttat ggctttcgtt tcccttttga
     7201 ttggtgtgat acaaggttct gggatcggta atgtatttgc taacattatg gcacctttag
     7261 caggaaatgc agttggatta acaatcattg gctttatttg ttcactgcca tttttatctc
     7321 ctttgcttgg tccaggggca gttattagcc aagtgattgg aacattgatc ggtgtagaga
     7381 ttgggaaagg aaatattcct ccccaattag cattaccggc actatttgct atcaatactc
     7441 aaaatgcatg tgattttatt ccagtcggtc taggtttgga agaagcaaaa gctgagacag
     7501 tagaagtagg tgtaccatca gttctttatt caagatttct taacggcatc ccacgagtta
     7561 tcattgcttg ggtagcaagt tttggattat atagctg
//
LOCUS       DAIGWC010000100         6999 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.103, whole genome shotgun sequence.
ACCESSION   DAIGWC010000100 DAIGWC010000000
VERSION     DAIGWC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.103"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            318..677
                     /locus_tag="NOB74_002548"
                     /pseudo
     CDS             318..677
                     /locus_tag="NOB74_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(982..1944)
                     /locus_tag="NOB74_002549"
     CDS             complement(982..1944)
                     /locus_tag="NOB74_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1221684.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGESI"
     gene            complement(1946..3385)
                     /locus_tag="NOB74_002550"
     CDS             complement(1946..3385)
                     /locus_tag="NOB74_002550"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HCI1221685.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            3570..5516
                     /locus_tag="NOB74_002551"
     CDS             3570..5516
                     /locus_tag="NOB74_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HCI1221686.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINAPSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5780..6652
                     /locus_tag="NOB74_002552"
     CDS             5780..6652
                     /locus_tag="NOB74_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI1221687.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         2227 a         1212 c         1249 g         2311 t
ORIGIN      
        1 attataaata actcataaaa aatattttga ctttcaaaat cacttttgct accagaagtt
       61 gaggcgaagt gttttaagca tagttgtacc ctagtttgac cgttaaaaat aaataacgat
      121 cgctagagtg caactatgtt tgtttgctct accgtcagcg tcggcttggc ctctcacatc
      181 cattaccgtc gggatcatct ccgttacata cccttacaaa atacgccctg taagcattgc
      241 atgaaaccac cgtgcatttg caccgtattt ccgccctagc cgttcaaatc ggtcgctacc
      301 accattcaga aacacgtgcg gtaatggaag gtttggagga agctatccag accactaacg
      361 attgtcccta tcgtcgtacg tttcactcag atcaaggttg ggcgtatcaa atgaaagctt
      421 atagaaacaa attgaaggag tacaaaatct ttcaaagcct gtctcggaaa gggaactgct
      481 tagataattc acttatggag aatttttttg gcttattaaa acaagagatt tttcacggga
      541 aagtttataa ctgtttcgag gaattaaaat cagccatcga tagctatatc tattactaca
      601 ataatgaacg gataaaacag aaattaaact gtcaaagtcc cgtccaattt cgtaaaacaa
      661 ccgttacggt tgtgtaaaaa tatcatttta gagcatgaaa aaaggagtgg atttctccac
      721 tccaaaaaag tctaactttt gggggtcact acatttttga tcctttttat ttgattaatt
      781 atatccagct ggataataat tttgggggca acatttctat cttactatta tcttcctaaa
      841 gtagtagact ttcttattgg gaaaaattac aacaaaaagg agtggcttag ttgacaactc
      901 ctttttgttt acaaatcaat tggatatcta caaattgtat tttctaacgg attttataga
      961 cattaaaaaa ttaatttgac gttaaatact ttctccagaa agtattgaga ttggtaaaat
     1021 ataatcctta tttgtctttt cgcctttaat ttttttcaga agaatatcaa caataagact
     1081 tgcaatttca tcaattggtt gtcttattgt tgtcaattgt gggaaaaatt tctcaatgaa
     1141 agaggtacca tcgtatccaa taatttttaa atcttctggg atattaagtt taagttgatg
     1201 agcaattttc atagtgagaa tggctgttaa atcatcagaa acaaaaatac catctggttt
     1261 gtgatttata atagttgact ttatttccat ttcacgacgg atagtagaca gattattagg
     1321 aattttgaaa atttttccat ttggattttg aaaagaaaaa cctagtgcac gtaattctgt
     1381 gggagaatcc gtgttatcat ttcctgtaat cataatggta ttttgacaac catttttttg
     1441 taaagtctta gctgcaagtt ttcccccttc aaagttatct gaagaaacaa tggaaacatt
     1501 aggagctaaa tttctatcaa aagcaacaat aggtgctctc acacgctcat aatcagcaat
     1561 tccaagatta tggcttgatg agattatgcc atcaacttgg ttggcttcaa gcatttcaat
     1621 gtattctctc tctttagcag gatcattttg actattgcaa ataatcgttt tatatccatg
     1681 tttaaataac tctatttcga gatactcaat gagttcagag taaaagatat tactaatatt
     1741 aggaaaaata agaccaataa gctgaggtga ctttccttga agtccacgtg ctaaattatt
     1801 tggtttataa ccaagagttt tcatagcttc atgaactttt tgttttgttt tttctgataa
     1861 atatccctta ttattaatga cgcgtgaaac ggttgttggg ctaactccag ctaattcagc
     1921 gacatcagtt aattttgcta ccattttaat attttaattc aaagtatttt ccagtaggtt
     1981 cgcctgattt gatttgaata ccattttggt gattttcagg gaatacacga ctagtaaaca
     2041 ctttttctcc tttattaata aaaatctcaa tgattgagtt atctacaaaa atgttagcag
     2101 ttgtttcttt agtatcaatt gagcattcac gaatcgtacc aaagtcagtg gcatattgaa
     2161 tgcctgcttt gctgcgatct aaaataattt ttccttcttt ggtatctaca atcaagctaa
     2221 gtccatttcc tttactatca gagaaaagaa gtaactccga tttctgattt ggaggaaaag
     2281 ttagttcaag ctcataagta ttatttgttt ctgcttttgc tgtaaattgt tcagaactag
     2341 cacgtaatga tgtaatagct tctactggat attggtaaag tttaccatct tttattgaaa
     2401 gttcttttac aagactcatt gctccctgat aatcatactt atcagttgga taatcgatat
     2461 caggtagtcc aatccaactg acaatcagag cacgaccatc aggagtattg aatccttgag
     2521 tcgcatacgc ttcaaatcca taatcaagat tttgaatttc tgaagcgccc acaagtttta
     2581 ctttttctat gtcaagcgat tgacagatct taaaagtatt cggatagata ttcccataat
     2641 ttagctcaga tttatccaac ccttgaggac aataaatgag aacaggtttt ttgtctacaa
     2701 atactagatt tggacactca atcatgtatt ctgaaccagt gccgccaaaa tcaaggttgc
     2761 caacttcctc ccatgtttcc acgttattgt catccgcttt gtaaagtttg ataaagcctg
     2821 atttttctaa attttgtgct ccaacaatcg catacaattg tccttcataa ttaaacattt
     2881 gtggatcacg aaaatgatca gttacatcag caggtttatg aataagaaca ttctcacctt
     2941 tcgtaatgtt gtagtcttta tccatccatg ctccgatttg aagtgtatca cgttcccaat
     3001 tttcatttcg aacgtttcct gtatagagta agaatagatt cccctctatt tcatatgcag
     3061 aaccggaata agcgccgtgg ctatctcgtt ttgtgtctgg aagaagttct gctcctgtta
     3121 catgaaaatg aactaaatca tctgattcat tgtgtaccca ttctttcaac ccatgagcag
     3181 ctccaaatgg ccaattttga taaaaaagcg tatattttcc gttaaaaaaa gaaaaaccat
     3241 taggatcgtt taacaatcct gttttaggtt cgatatgata gctagcacgc caaggtgatc
     3301 gttttacatt atccttaatt ttatccatct catctttagt ccaatcagaa taagcacgat
     3361 atcgtatttc tcgaggtaag ttcatatttt actccttcaa tttatctttt tacaactagt
     3421 atggtaaacg ttttccgttg aaaaatcaat catttcattt aaaaaaataa actatatgac
     3481 aaacgtttga catattttta agatatgcta aaataaattt gcatttcagt gaaccgtttt
     3541 cacgtaaaaa taaaaaagga gtgattcgaa tgaattacag taaagtagct tccgacgtaa
     3601 tacaagcggt cggaaaagat aaccttattg cagctgcaca ctgcgctaca cgtcttcgtc
     3661 tcgtactaaa agatgacacg aaagtgaatc aaaaagcttt agacgaaaat ccagatgtga
     3721 aaagcacatt taaaattgat ggacaatatc aagtgattat cggtgcaggt gatgttaatt
     3781 tcgtttatga cgaacttatc aaaaaaactg gactttcgga aatttcaaca gatgatttaa
     3841 aacaaattgc tagtaaagat aaaaaattca accccattat ggcattaatt aaattattat
     3901 cagatatttt tgttccaatt atacctgccc ttgttgcagg tggtttatta atggcattac
     3961 aaaacttttt aacagctgct ggactttttg gaccaaaatc aattgaagaa atgtatcctg
     4021 cgattgaagg tatttcctca atgatccaac tgatgtccgc tgcaccattc atgttcttac
     4081 caattttagt aggtatttca gctgctaaac gttttggagc aaaccaattt cttggtgctg
     4141 caattggtat gatcatgaca acaccagatc ttggtggctc aactgaatat tggaatattt
     4201 ttggttatca tgtttcacaa acaaactatg cttatcaagt tattccagtt ttagcagctg
     4261 tttggatatt atctatatta gaaaaattct ttcataaaaa attgccatca tctattgact
     4321 ttacattcac gccattatta tcagtaatga ttactggatt tttgactttc acagttattg
     4381 gccctgtaat gttattgttg tctaatggaa ttacagacat tattgtttgg ctatataaca
     4441 ctactggatt tattggaatg ggtatttttg gaggaacata ttcacttata gtcatgactg
     4501 gtttacatca atcatttcca gctattgaaa ctcaattact ttcagcgtgg acaaatggta
     4561 tcggacatgg agactttatc tttgtagttg catctatggc aaacgttgct caaggtgctg
     4621 caacatttgc catttggttc ttaactaaaa attctaagac aaaaagtctt gcttcctctg
     4681 cgggtgtctc agcacttctt ggaattacag agcctgcctt gttcggagtt aacttaaaat
     4741 accgctttcc attcttttgt gctttaattg gttcaggaat tgctacagca gtagcaggat
     4801 tacttaaagt agttgctgtt tcacttggtt cagcaggttt cttgggattt ctttcaatta
     4861 atgcaccatc tattccattt tacgtattgt gtgaattgat tagctttgta gttgcttttg
     4921 caattactta cttctacggt aaaacaaaag ctgctggtat ctttaaagca gaagaaattg
     4981 ctgaacaaac accagttaat tcttcaaaag tagcaacaac agatccaata tctactgatg
     5041 ttgaatcaac acaaacaaaa gtttcatcag aaacaattgt tagtcccatt tctggtaaag
     5101 tgattagtct ttcttcagta aatgatccag tcttttcatc agaagctatg ggaaaaggga
     5161 ttgccattaa accaaatgga aacacggtcc attctccagt agatggtact attcaactca
     5221 cgtttgaaac tggacatgct tatggtatta aatcaaataa tggtgctgaa gttctaattc
     5281 atattggtat tgatactgta tcaatgggag gaaaaggatt tacacaaaaa gttactacta
     5341 atcaaaaagt tagaaaaggc gatattcttg gagcatttga ccgttcaatg attgagaaag
     5401 aaggtcttga tgatacaaca atgattattg tgaccaatac ttcggattat tcagaagtaa
     5461 atatagtagc tgaaaataca gtcactgagg gtactgattt acttgaaatc aaataaatat
     5521 atttccctga gtaaagatgg aattttcttt ccaaaatcaa ataatataga ttaatcaaat
     5581 atttgagaat aacattttat ttaatctttt catatatcaa ttgtatgaaa aattattaga
     5641 attttaaaaa atgataaaaa ttcaaaaaga aaaaatagta gttatttact tgtcatgtta
     5701 ctaaataaaa aaataattta aatatgatat atagtcattt atttagtgat ttcattctaa
     5761 aataaaggga gaaatgtcta tgctatacgg tgcaattgaa gcaggcggca caaaatttgt
     5821 gtgtgccatt ggcgatgaag aaatgacgat caaggaaaga gtgagctttc cgacaacgac
     5881 acctgaggaa acaatgcctt tagtcattga cttcttcaaa caataccaag cagatttagc
     5941 agggattggg attggctcat ttgggcctat cgatatccat cgcgattccg ccacttatgg
     6001 gtacattacc tcgaccccga aattggcatg gcaaaatttt gatttcatcg gtaccatgaa
     6061 aaaagaattt ccgatcccga tttcttggac aacagatgtc aatgcggctg cctatggtga
     6121 gtatgtcttc ggcagtggca aaggattgag cagtgtcgtt tactatacga tcggtacggg
     6181 tgttggcggc ggtgccttac aagaagggcg ctttatcgaa gggtttagtc atccagaaat
     6241 ggggcatatg ctcgtcgtcc ctcatccaaa agatgacttt gctggcagct gtccatttca
     6301 tggcaactgt ttagaaggga tggccgctgg acccgccatc gaaaaccgct tagggaaaaa
     6361 aggacaagag gttgcagaag atgatcctta ttgggaaatc gaagcctcct atattgctca
     6421 atgtgcctac aatacaacct tgatgttttc tccagatgtg atcatttttg gcggtggtgt
     6481 gatgaaacaa cgccatatgc tgcaaaacgt ccacgacgca tttgcaaaat tggtcaatgg
     6541 gtatgtcgaa acacctgagt taagcaaata tatcgtgacc ccagcattag aagacaacgc
     6601 tggaacgctc ggttgtttgg cattggctcg agaagcggtc ttacattcat aaacgaaaaa
     6661 aggctcttcg acatttagtg ttggtagaga aagatacaac tgaaaattta gtcataacca
     6721 gttaggcaga gtgcttaact ggtttttgtt ttacttggaa gatcaagcct tgaatgagat
     6781 aaattcttgc tcgaaagtta tggaaatttc gatagccgta ggccacttgt attgtgcaat
     6841 agttttttac aaaaaaaagg gggtgcggat atttttttgg acctttttaa caaataggtt
     6901 ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa agatagcagg
     6961 aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DAIGWC010000101         6869 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.104, whole genome shotgun sequence.
ACCESSION   DAIGWC010000101 DAIGWC010000000
VERSION     DAIGWC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6869
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.104"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..227
                     /locus_tag="NOB74_002553"
     CDS             <1..227
                     /locus_tag="NOB74_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HCI1221688.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            227..574
                     /locus_tag="NOB74_002554"
     CDS             227..574
                     /locus_tag="NOB74_002554"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221689.1"
                     /translation="MRKRTIKTQLAVSFLAIATLIIGSISLVALSLMNNHFSKYVEER
                     QEDLLNQYVYTIDLLWLNSGETWNSEELAALSEKVLENNIYFSIEDEQGNMVWELTGK
                     DLKSAQEKLKKMH"
     gene            571..1620
                     /locus_tag="NOB74_002555"
     CDS             571..1620
                     /locus_tag="NOB74_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1221690.1"
                     /translation="MKVSEKNSVKLDETIEVKKKLINDGNEFGKVTFYYFGPFAYTEH
                     DALFISSMKQSLMYVAIAALLVSFILASWISARLGLPLKHVSDFTHKLTRGEYADKIP
                     QETSIIEINSLIDSLNDLSNQLEKQHGLRKRLTTDISHELRTPLATLKGNVEGMIDGV
                     WKITPERLQSCYDEIDRLTRLIGNIEIINKIEAKYDHLNKTEFNIYKLIESVIENFAS
                     KIESKNLHVEIQGDNINISADKDKMNQVVINLLNNAIKFTQKEGTIKFSISKNKDHVL
                     LIVEDNGIGIEKDQQLHIFDRFYMADPSRSRALGGQGIGLAIVKSVIEAHKGSITVKS
                     KLGLGTKFVIKLPFQ"
     gene            1635..1841
                     /locus_tag="NOB74_002556"
     CDS             1635..1841
                     /locus_tag="NOB74_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221691.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1862..2458
                     /locus_tag="NOB74_002557"
     CDS             1862..2458
                     /locus_tag="NOB74_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HCI1221692.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
     gene            3410..4009
                     /locus_tag="NOB74_002558"
     CDS             3410..4009
                     /locus_tag="NOB74_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI1221693.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            4058..4774
                     /locus_tag="NOB74_002559"
     CDS             4058..4774
                     /locus_tag="NOB74_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HCI1221694.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            4788..5567
                     /locus_tag="NOB74_002560"
     CDS             4788..5567
                     /locus_tag="NOB74_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HCI1221695.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            5650..6006
                     /locus_tag="NOB74_002561"
     CDS             5650..6006
                     /locus_tag="NOB74_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI1221696.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            5996..6262
                     /locus_tag="NOB74_002562"
     CDS             5996..6262
                     /locus_tag="NOB74_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1221697.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            6421..6699
                     /locus_tag="NOB74_002563"
     CDS             6421..6699
                     /locus_tag="NOB74_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221698.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(6696..>6869)
                     /locus_tag="NOB74_002564"
     CDS             complement(6696..>6869)
                     /locus_tag="NOB74_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI1221699.1"
                     /translation="HRSIKRRHKLYQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFS
                     VCTEIRILLGIPA"
BASE COUNT         2527 a          957 c         1333 g         2052 t
ORIGIN      
        1 ttaaaacaac tgaatttgat attctacacg ctctaatgtc cacacctaat aaagtctttt
       61 ctcgtagtga tttgatagag aaagttaagg gaatagaatt tgatggacta gataggagca
      121 tcgattctca tataaaaaac ttaagacata aaattgagaa tgatgctaaa tcacctatgt
      181 atattttgac agtccatggt acaggataca gatttggtgg ccactaatga gaaaaagaac
      241 gataaaaact caattagctg tttccttttt agcaatcgca acattaataa taggatcgat
      301 tagtttagtc gcattaagtt tgatgaacaa tcattttagt aaatacgtgg aagagcggca
      361 agaagatttg ttgaatcagt atgtatatac aattgattta ttgtggttaa atagtgggga
      421 aacatggaat agtgaagaac ttgcagcact atctgagaaa gtattagaga ataatattta
      481 tttttctata gaagacgaac aaggcaacat ggtttgggaa cttactggaa aagatttgaa
      541 gtcagcacag gagaaactga aaaaaatgca ttgaaagttt ctgagaaaaa cagtgtgaaa
      601 ctagacgaaa caatagaagt gaaaaagaag ttaattaatg atggaaacga gtttggaaaa
      661 gtaacgtttt attatttcgg accttttgct tatacagagc acgatgcctt gtttatctcc
      721 agtatgaaac aaagtttaat gtatgttgca attgcagctc ttcttgtatc attcatactt
      781 gcttcgtgga tctctgctag attaggattg ccactaaagc atgtaagcga ttttacacat
      841 aaattaactc gtggggaata tgctgataaa atcccacaag aaacttcaat tattgaaata
      901 aattccttaa ttgattccct aaatgattta agtaatcagt tggagaaaca gcatgggctt
      961 cgaaaaagat taactaccga tatttcacat gaattaagaa ctccattagc tacgcttaaa
     1021 ggcaatgtgg aaggaatgat tgacggagtc tggaaaataa ctcccgagcg cctacaatct
     1081 tgttatgacg aaatagatcg tctaactcgt ttaattggaa atatagaaat aatcaacaaa
     1141 attgaagcaa aatatgatca tttaaataaa actgagttta acatatataa gttgattgaa
     1201 tccgttattg aaaatttcgc cagcaaaatt gagtcaaaaa accttcatgt tgaaatccaa
     1261 ggggataaca tcaatatatc tgcagataaa gataaaatga accaagttgt tatcaatctt
     1321 ttgaataatg ctattaaatt tacgcaaaag gagggaacca ttaagttttc tataagtaaa
     1381 aataaagacc atgttctttt aattgttgaa gacaacggca tcggtataga aaaagatcag
     1441 caacttcata tttttgatag attttatatg gctgacccct ccagaagtag agctttaggg
     1501 gggcaaggta tcggattagc tattgtaaag agcgttattg aagcgcataa aggtagtata
     1561 actgtaaaaa gtaaattagg tctaggaact aaatttgtta taaagttacc atttcaataa
     1621 aggaggagag ttatttgttt caaaaacaga taaaaattgc taaactagta tgtgaatgtt
     1681 gggcaaaaaa aatatttttt caactgattt cgatagatag tgtcgaaaaa gttcatttag
     1741 atatcttatc aaattctgta gtaatctttt ctaagaagga cttatcaata gctacaatta
     1801 aaaaagaagt ttttggatta caaatttatg agatgaccta aatgtgatta attaaaggag
     1861 gatgaagaca gtgaaaaaga tgacaaaatt agtatttgca agtcttggaa ttattgtatt
     1921 tttaggagcg tgtagcaatc aaagtgaatc gaataattct aatagcacaa acgaggaatc
     1981 gacttctaca gcgtctagtg aaatgaatag tatggaggga atgaatcacg aaggtatggt
     2041 tccttcttca atgaaagatg ctgcgaaccc taaattcccg gtgggaagta atgttatact
     2101 gctaggcgat catatggaag ggatgaaagg tgcaaatgct caagttgtag gggcctttga
     2161 tactacaatg tatgaagtaa gctatgagcc aaaaactggg ggaccaatgg ttaacaatca
     2221 tcgatgggta gtacaagaag agttaaaaga tactgagact gtagcaaatg agggcgatac
     2281 tgttatcttg aatgccgatc acatggatgg gatgatggga gctgaagcaa aagtagataa
     2341 atctattaca ggaactgttt acgttgttaa ttacactcca accgatggtc aagaagaagt
     2401 taagaatcat atgtgggtaa ctgaagatga gatggaatat gacgaaaata atgagtaatt
     2461 ttatatacta aaccaacaag ctggtacatg gtcttcgtat tctcaacatg aggaatatga
     2521 gctctttgtt aataaggact gatgagttgt gcaaaatcaa atctgggtca gaacgaacct
     2581 cattctggct cagatttttg gctcttcgac atttagtgct ggtagagaga caactgaaaa
     2641 tttagtcata accagttagg cagagtgctt aactggtttt tgttcgcatt tattattctt
     2701 ttgatattgg ctgcttgccc ttcaatttta tttggtttct taatcaactc ttcatataac
     2761 cccaaatcat atattaatga ggtgcctcct attcctataa atctatctct tctttaatag
     2821 tatgagaaaa gtctactctt gtagatttaa attgtcaaca aaaaatttac agatgtaaat
     2881 gataagttga atagagaaag ataaattatt tttttggtat tcatataagg ttaattatgt
     2941 attatcacaa aatgattgtt gtcgaataac taaaagtgtc aaaacaatga tgaaatcatt
     3001 tagttcttat aaattagaca agagaaaata aatattccat atctacttta ttggatccat
     3061 aacatgacta aattctgaat actttttaaa gcttatcatt tggtaaaact gaatataagt
     3121 taattatata gactgaaaat tttgaatttt cagaatagaa taacttaaaa gtactgacaa
     3181 attttttaaa ggggcaatat taatgttctg agataatcaa atcttaccga aaatatcaaa
     3241 agtccaatgt gacacaattg gattttgtca cattcgttaa aatcgctcca tccttagagg
     3301 ctctaatagg aaatcacttt tcttttagcg ccttttttct atagcttgtt taaatgtgac
     3361 ttattatctg ttataatcgt attaagtaac atttgagagg tgtctaaaaa tgaaaagcgt
     3421 ggaaccgatt cgcgacaaaa aaaagatcga tgccatgaag gccattttgg cttccggaaa
     3481 atatgggcaa cgaaatttgg tgcttttttc gatcgggatc aatacagcct atcgaatctc
     3541 cgatttaaga cagttaaaat taagggatgt gctagaaatt tcccgtgggc gggtgatcgt
     3601 caaagaacgt ctggccatga aggaacaaaa aacggccaaa cacaattcgg tcttcatttc
     3661 gaacaaattg cgaaaagtga ttcttgatta tgttcaatcc gaatttcctg agcagttgca
     3721 agcacaagac ttcagcaagt atttgtttcc aagtcgaaaa ggagcagata cgcctttgac
     3781 ccgacaaagc ctttggcgga tcattcatga agcaggaact gcagttgggt taaaagaaat
     3841 tggtccccat tcgatgcgta agacctttgg ctatttttta tacaagcaag gaaccaaaac
     3901 agagatcatt cagtcgctgc taaaccattc ttcacaacgg gagaccttac gctatattgg
     3961 aatcacccag gaagacaaag atactgcagt aaagagtttg gatttatgac agaataatgc
     4021 cctatataat agaaggaaaa attcaagagg tgagaaaatg aacgaagaaa agcagcctaa
     4081 ctttcctgat aaatatcact tatctcgcaa agagtctgtg tatttattga agaaaaacat
     4141 tgtagaactg gtgtataatg cggggaaatt tgaagggtta aatacaacgt tgttacaaac
     4201 agaagggatt attaagtata atcgggccaa caacgtggct gtagatgatg tcctgaccgt
     4261 cgttaactta aaaagaggct ttgaaatgct tttaaatgac gtacaggagc ccctgttaga
     4321 gacaagtaag cggattaatc ggatcgttgc agcagaggat gcgctttttc ccggtgaaat
     4381 acgaaccggt ggggtagaat tatcgacgat tcaaggaaga tatgtgccac caatgttaac
     4441 tgaagacgag gtaaacaatc aatatggtga gataatgaat caagagatat cagatacgga
     4501 aaaagccctg cgactgtttc tattcatttc gaaaaatcaa atattctgga atggtaatgt
     4561 gggtacagcc ttgttgattg cgaataagat tatgtttagc aacggtttag gactattatc
     4621 aatacccgaa aatgtattta tgaaatttaa cgaactttta tcaaagtatt gcaacagtaa
     4681 tctattagtc aatgagtcaa atattatatc atttttatat gaacagtgta tctttggtat
     4741 taattatttg aaaataatcc aacatacaat ttaagaggta taagtaaatg atgactatag
     4801 acgaagcaaa acaattagca acttattttt cagttggttc agcgggatat attttagact
     4861 ttactaatgt aacgtggaac atatttacaa agaaaatcgt agggattgaa atacaaaatc
     4921 attatggggg ctcaaaggga gtatcctttc aaaagtttct gcttgacgat caatttgatg
     4981 attcgttaaa gaatcggtta atccaatctt taaaaggtat tatggatcga gataaaaaat
     5041 atgaatctac tgaaatgaat cccatagttc agttgctttt tgaggaagta tttaaagaag
     5101 atacttcaac tgcattaaga aaaatgaaat tttcaagcga gattgattta ctttatattc
     5161 ggcagctacc cattaggatt caaacagata ttaaaaacaa ggattttgac tctgttttga
     5221 caaaagcaaa tactttaata gatgaagttc taaaatttat tattgaaaat accgaaggac
     5281 cgagtgttaa tattaattta tttaagtcaa aagaattaag aaaagaagta tttggccgcc
     5341 tcaatattaa aactgaaaaa gatatggata atagaatcaa agcccttgtt ggagcactca
     5401 atacattatc agataaaata ctcgaaatga gaaatagtca aggagatgct catgcacatg
     5461 gctcaaatag aatagtaatt aaggaagaag aagcaattct tgttgcaaat tcttctatgg
     5521 ttttgtgcga gtatgtgttt actaagtata aaggattaaa tagataataa aatgcatatt
     5581 ttatagtata caattcgaat ttttatgtta tatactataa tataaaatca atatatgata
     5641 taattgggta tggaaaaaat atcttttgaa acatttaaaa gacccaatgg tcatgatgaa
     5701 tttttagaat ggttggaaac attaccaaaa aaagatagtg cgaagctttt acgtacaata
     5761 gaagaaacag aaaagaatgg gatgctagta gctcaacggt tgaaatgggt gaaaaaatta
     5821 gacactaatt tgtacgaatt aagaagtaag gtaggatcaa acatccaaag agccatctat
     5881 ttccatgtgg acaatggaag gtatgtcatt actcacggat ttactaaaaa aacggagaaa
     5941 acaccaataa ctgaactcaa gcatgcaaaa gaacttagag aggagtggtt cacaaatgat
     6001 gattaaaaaa ttgattgaag aaaagaaaaa agataaagat tttgcagaag catatgaccg
     6061 tgaaggaaga aaactcgaaa ctgcggttgc tctttatcat gctcgggagg aagcagggct
     6121 aactcaagcg gagcttgcac aaaaagcaca tacaactcaa tctactattg ctcgaattga
     6181 gagaggggat aacgtatctt tcgataaact tgatgatatc gccagggcat taggtaaaaa
     6241 gctggtagta gaatttgctt aaaagcgagt tgaaaatata tctataatag gctcctaact
     6301 aatcaattag tttagtgggc ctttttttac tagatagata aaggttgtac tatagtgtaa
     6361 aagacaataa attttatact aaaattactt taaagagaac tagagagaaa ggtacaataa
     6421 atgaaaacca taaatcttat aaaagtattt atagcatcac caggtgatat agcagcaaaa
     6481 aggaatgaag tagaagaaac catatataga tggaatatag aaaatacaga taatacaaaa
     6541 gtgattttga tgcctatacg atgggaaact aatgcgattc ctacttatgt aaataatagc
     6601 tctgggcaaa gtgttattaa taaacaaatt gtagaaaata gggttctgct gcaaagtttt
     6661 aaaaataaaa tcagtttttg tattatttct tcattttaag ctggaattcc caataatatc
     6721 ctgatttcag tgcagactga aaagccgaag agagtgcctt cttttcggct tttcttgtag
     6781 attcctcgaa tggtttccat ccctttaatt gtggtggaag ctgtacgtag actttgatac
     6841 aatttatgtc gacgttttat cgatcgatg
//
LOCUS       DAIGWC010000102         6507 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.105, whole genome shotgun sequence.
ACCESSION   DAIGWC010000102 DAIGWC010000000
VERSION     DAIGWC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.105"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(43..816)
                     /locus_tag="NOB74_002565"
                     /pseudo
     CDS             complement(43..816)
                     /locus_tag="NOB74_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            837..2039
                     /locus_tag="NOB74_002566"
     CDS             837..2039
                     /locus_tag="NOB74_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HCI1221700.1"
                     /translation="MCTKLLQNTAHKNPYKTVDEATQLDLVIVVNQLLTGYDSKWVNT
                     LYLDKSLEYQNIIQAFSRTNRLNGPEKPFGTIRYYRKAHTMEQNIEEAIELYSGKQAK
                     GLFVEKLYNNLEKLNDIFEEIKSVFNISGIENFSHLPEVPGEIKQFVNLYNQLIHCYE
                     SAMIQGFTWAKSTYEIQDYEPITVVITEYEFNILAQRYSEIEREPRDGNDSIAYDIDY
                     QLPEGSRSRINYEYLNTNFKKYMNIKEERDSNLIQSLLNDLHRTFAQLPVELQPYAEM
                     ILNDVNNGELVIKEGWEFTDYLNEYQLSEEDDFIQDLVDSTNINEALLREMLDLRLTE
                     VNINEYSRFDKLKSSVNVGHFSGYIEKNLGKMVIPIKVNMLIDRLLRAFLLEDVFDVT
                     EYIKNYFN"
     gene            2772..3740
                     /locus_tag="NOB74_002567"
     CDS             2772..3740
                     /locus_tag="NOB74_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1221701.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            3751..4566
                     /locus_tag="NOB74_002568"
     CDS             3751..4566
                     /locus_tag="NOB74_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HCI1221702.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            4634..5344
                     /locus_tag="NOB74_002569"
     CDS             4634..5344
                     /locus_tag="NOB74_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1221703.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            5380..>6507
                     /locus_tag="NOB74_002570"
     CDS             5380..>6507
                     /locus_tag="NOB74_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HCI1221704.1"
                     /translation="MKQVLRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         2190 a          999 c         1328 g         1990 t
ORIGIN      
        1 cttagtccga tatgcggcgc gttctgtgcg ccgcatattt ttttagtttt caaagatcag
       61 accttgttgt aaatagatcc gtgcccgaaa gttataaaag ttgcgataac caaacgcaat
      121 tcgtttaatc agcttgatct tgttatacag cccctcagtg acgccgtttg agtgggacac
      181 cttaaaggca tttgaaatac ccgattggta gcgatggaag atcgtgaatt tctttttaaa
      241 cgactgaggt aacgtagatg aaattgtttt aagggtttct tgaaagccta ccgtatctcg
      301 tttaacgaaa taatagcgta ataattgaca aaaatgatac gcagttcgca attcttcgtt
      361 gtagcttaac agctcattaa cgatttctgt ttgactaatt ggtcgtttaa acagtcgatg
      421 ataatgccgt ttgagtgcct cccatgtcgt ggaatctttg agtaagagtt tccaatatcg
      481 cttgagccga cggtacttct tctgattttc agagtgtgag gttcgaaaac gattcatgat
      541 ctggacacgt aattgattga agctgcgatt gatgtgttgg acaatatgaa agcggtcagt
      601 tacgatctcc gcatttggaa agaccgtttt aagcaactga caatagctgg cattcatgtc
      661 catcactagg tacttgacct ttaaacgggc ctttctagga aagcgcagga agtattgagt
      721 tagtttgtaa agtctgcgat cttcaagggt cgtaaatagc tgattggttg tcccatcaac
      781 acaaataaaa ctcatggaac cagaagtggc aacattgtgt acttttcttt gcaatcttgt
      841 gtacaaaact attgcaaaac acagcgcata agaatcctta caaaacagta gatgaagcaa
      901 cccaattaga tcttgttata gttgttaatc agctcttaac gggttacgat tcaaaatggg
      961 tcaacaccct atacttagat aagtcacttg aatatcagaa cataattcag gctttttcac
     1021 gcacaaatcg tcttaatggt cctgaaaaac cgttcggaac cattcgttat tatcgtaaag
     1081 cacatacgat ggaacagaac attgaagagg ctattgagtt atactcaggc aaacaagcaa
     1141 aagggttatt tgttgaaaaa ttatataata acttagaaaa gttgaacgat atattcgaag
     1201 aaattaagtc cgtatttaat atttctggca tagaaaactt cagtcattta ccggaggttc
     1261 caggggaaat taagcaattt gtaaatcttt ataatcaact aatccattgt tatgaatcag
     1321 cgatgataca gggattcaca tgggcaaaat cgacttatga aatccaggat tatgaaccta
     1381 taacagtagt aatcacagaa tatgaattta atatcttggc acaacgttac agcgagatag
     1441 agagagaacc tagagacgga aatgatagta tagcgtatga cattgattac caattacctg
     1501 aaggtagtcg tagtcgtatt aattatgagt atttaaacac aaacttcaaa aaatacatga
     1561 atataaaaga agaacgtgat tcgaatttaa ttcaatcatt gttaaacgac ttacatcgca
     1621 catttgcgca attaccagtg gagttacagc catatgctga gatgattcta aatgatgtaa
     1681 ataatgggga attagttatc aaagaaggat gggaatttac tgattacctc aatgaatatc
     1741 agcttagtga agaggacgat tttatccaag atttagtgga ttcaaccaat attaatgagg
     1801 cattattacg tgagatgttg gatttacgct taaccgaggt aaacattaat gaatatagtc
     1861 gatttgataa attaaaatca agtgttaacg taggtcattt cagtggatat atcgagaaaa
     1921 atttaggtaa aatggtaata ccaatcaagg taaatatgct aattgacaga ttattgcgtg
     1981 catttttatt agaagatgta ttcgatgtta cagagtacat aaagaattac tttaactaga
     2041 gtacacctac atcttatagt acataaaaaa attcatcttt tttagtttaa taattcacca
     2101 aaaaggtgag taatgccatt tttgaaaatt gagcttgttt tatgtctaca tctgtatccg
     2161 tatataatcc aaaggattat aaactcagaa gagtctttat tttttctgaa tataactact
     2221 gtatcaaaaa caatcgatta tgagacaaaa caaaatgacc tcttttattt aagaaaggag
     2281 gtcatttttt gtatcataaa ttgtattaaa atcaatgtat cactttttaa tcaattttaa
     2341 gaccataaat tgcgtactaa aagaaattct gcaattcaaa ataaagcatt ttaagccatt
     2401 ttcaaattta agtgcaccca tctacccgtc aaatcacttt attttccact ccagtagttt
     2461 cctaattcaa ctgtgtgcaa aacgatttct tctaaacaaa tcaagacaaa cttataaacc
     2521 ttcatcccag caccataatt atttaaatca taggcatttt tcgaaattag tatatgtact
     2581 caagtttcac tgcagattat ttatattttt tagagaaata aatttttcct attgacaaac
     2641 acaaagaaag cggatacaat acaattatgt cacatgacgt tatatgacgt tatgtaatat
     2701 ctttacattt aatcagttac ttttattttg gataaaatta acatttttaa aattttaagg
     2761 aggaaatgtt gatggatgta gcaaaaacgg ttaacgcaat tgtagaaaaa aatgatggag
     2821 agatttctgg aatttatttg gtggcttgtg gcggttcgct ggtagatatg tatgtctcag
     2881 attattttct taaagccgaa gcatcgaagt gtattacagg cttatataca gcgaacgaat
     2941 ttaaccatgt aaccccaaag caattagatg ataaatctgt tgtcattcta tgttctcatg
     3001 gaggaaatac agcagaaacg gtaaaagcag gagaagtcgc tcaagctaga ggagctgtga
     3061 ctgttggtct gactcataat aaaactgcgg atttattaaa ggtttctgat catagtttcc
     3121 tttacgaatg gggagatgat gcaaaaatag tcaataatcc tatggccatc attcttgatt
     3181 taactgtatc tttggtcaat gttaccgaaa catttgaaca ttacggtaaa ttcagagaag
     3241 gcatgaaggt tatcgatacc gtaattgaaa atggcattaa gcaggtgcag gatcgtatta
     3301 aagtgtttgc tgataagtac aaagatgaaa caatgtttta tatcttaggt agtggaccat
     3361 catatggaca tgcttatggt ttttcaattt gctctttgat ggaaatgcaa tggcttgatt
     3421 caacttctgt tcattctgga gaattcttcc atggaccttt tgaagtaaca gacaaagata
     3481 cgaattttat tctcttgatg agcattggac gcactcgtgc tttagatgaa cgggcaaaac
     3541 gattccttga taaatatgca gaaagagtag aaatcgttga tgcaaaggaa ctaggattgg
     3601 atatgatatc agatgaagtt tctgaattct tcaatcccat tttattctac agtattcttt
     3661 cagaatatcg ttcagcttta gcagatgcac gcaatcatga tttagatgtt cgtcgctata
     3721 tggggaaagt ggagtactag gaggattaaa atgaaggtat taggcttagg tgataacgtc
     3781 gtcgataaat atgaaaatct gggaattatg tatcctggag gaaattcatt gaattttgca
     3841 gtttttgcaa aaaaactggg acatgaaagt agctttatgg gagtttttgg ctcagatgag
     3901 gaggcagctc atgttttatc agcaataaaa aaaataggac tggacaacag tcactctcgc
     3961 tttgaaaaag gcgagaatgg ctgtgccaga gtgaagattg atgagggcga ccggattttc
     4021 cttggcagca attcgggagg tgttactcgt gaatacccga ttcagcttac tgaagaagac
     4081 agagaatatt taaaccagtt tgaattgatt catatgggat tatatagcca tgtcaatcat
     4141 ctattagaag agttacaaaa tgtttctgga aagatttctt atgatttttc tgacgacttt
     4201 acggaagaag aggttcagcg ggcaattgat aaagttgatt ttggcttctt ttctatagaa
     4261 gacttttccg atgaagaagt aaagcagttt ttgatgaagc atttttgtga gcgaaatgat
     4321 gtattgattg caacccgagg agaaaaaacg gctattggtt atgatggagc aaagttttat
     4381 gaagtgaacc ccgtgctaga agaaccagtt gatacaatgg cagcgggaga ttctttctta
     4441 acagctttcc tactttattt tctcgaaggg gacgatatag tcaccgcgat gaaaaagggg
     4501 aatgaatttg ctgggaagtc ttgtctggtt gacggttcgt tcggctttgg tattcattac
     4561 gattgagctt gttttaaatt cctgcatttg ataacctaaa gaaagaaatc ccggtaaagt
     4621 ggaggttaaa aaaatgctgg atacaaatgc acaattacca ttgtacttac aattaaaaga
     4681 aatattaaaa aataaaatca atacagggga gtatcccgag aatacgaaaa ttcccgctga
     4741 atcagagctg atagaaagtt atgaggtcag ccgaatcaca gtgagaaaag cagtagaaga
     4801 actggtagaa gaagggtacc tacttaaaaa acaagggaaa ggaacttttg tcaaccggca
     4861 taaagttttt cgtaaaattg aatatgttat gggtttcagt gagagttgta aatctaatgg
     4921 ttttacaccg actagcattg ttttggaacg caagatcatt ccagcaactg aagggatggc
     4981 aaaaaaactc gatatcgctc aaggtgatga tgttttatat atccagagaa agcgaatggc
     5041 ggataacatc cccattatgt tagaaaacaa ttatttttct tatgaaagat atagtttctt
     5101 aatggaggaa gagctgactg attctttgta tgaagtactt aaagtccaag gtaccttagc
     5161 catcaatcct ggggaaactg cacttgaaat tgtcacagct gatgaccaaa ttgccaaaat
     5221 aatggaagta gctgttggga cgcccttttt ctttatggat actttaatca acgatcaaaa
     5281 caacatacca attcatgtag gtaatcaata ttacctggga gaagtatatc gtttttactt
     5341 atgatttcct gttttgattt caaggagtag attttattta tgaagcaagt attgcggtca
     5401 aaaatgattt ttgatggaga gcagccacct ttcaaaggtt atattgtaat caatgaaggg
     5461 atcattgaaa aggtggaaaa caactggaat tacagtgatc tattaaatga aaacacggaa
     5521 ttaattgctt atgatgatca attcgttatg ccagcaattc atgataatca tgtatttttc
     5581 agtggttatt tggctatgaa tgctggcata gatttaagcg atacatcttc agctaacgag
     5641 gctgtagagc gtattaaagc tgtaatgaac cataaaaaag cagatgaacc aatttatgct
     5701 catggctggg atgctgccct gtggaaaact gacccatcag aagagctatt gaatgaaata
     5761 aaccactttg gtccaatcac agcgatcgac aaaaatcgca gccattgttg gatgaatgct
     5821 attgctaagc agacttatgg ttttacagaa aaagaaacca gtgctgaaag tcgagtatta
     5881 ttaattaagg aaatgctagc aaacaaaaag cttttagcag aggtttacgc tgaatttgaa
     5941 gcattactgc tttcaaaagg tgttatatca atgaaagaaa tcgtttttga tgacgcagaa
     6001 tttctttcta atatacctca gaggaaaata cttagtaacc tatatgtgca ggcagtccaa
     6061 gaacctctac agcatgaact tctatatgag tataaggaaa aagttttccc tgaaaaggtc
     6121 cgctttggtg gagtgaagat catggtagat ggtgttgttg cggatagaag tggagatatt
     6181 tacggtgttt atcagtcagg agtagcttca cccgagattg actatgaggc aattaaagca
     6241 gaagttgctg cattcaatga agtagagatt ccttgctgtt tgacaacgga aggagataaa
     6301 gcgggttata aagctgcgtc aattcttgtc gaatttggaa agcggttacc tgaaggcgtt
     6361 tttaattcga ttagtgattt ggaaatggtt actcaaaaga cagcagaaaa aatgaacgaa
     6421 ggacaagtag tagcagaggt atatccacaa attctcggct tgaatcaaac gttagaagag
     6481 gcttacatgt caactgttat aaaaaat
//
LOCUS       DAIGWC010000103         6481 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.106, whole genome shotgun sequence.
ACCESSION   DAIGWC010000103 DAIGWC010000000
VERSION     DAIGWC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.106"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            591..1280
                     /locus_tag="NOB74_002571"
     CDS             591..1280
                     /locus_tag="NOB74_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1221705.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="NOB74_002572"
     CDS             1267..2475
                     /locus_tag="NOB74_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1221706.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="NOB74_002573"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="NOB74_002573"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HCI1221707.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="NOB74_002574"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="NOB74_002574"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HCI1221708.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
BASE COUNT         1976 a         1213 c         1252 g         2040 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgcggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 t
//
LOCUS       DAIGWC010000104         6347 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.107, whole genome shotgun sequence.
ACCESSION   DAIGWC010000104 DAIGWC010000000
VERSION     DAIGWC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.107"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            290..1135
                     /locus_tag="NOB74_002575"
     CDS             290..1135
                     /locus_tag="NOB74_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1221709.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="NOB74_002576"
     CDS             1416..2636
                     /locus_tag="NOB74_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HCI1221710.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="NOB74_002577"
     CDS             2633..5353
                     /locus_tag="NOB74_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1221711.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="NOB74_002578"
     CDS             5337..6281
                     /locus_tag="NOB74_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI1221712.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2363 a          983 c         1224 g         1777 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 tcgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttc
//
LOCUS       DAIGWC010000105         6174 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.108, whole genome shotgun sequence.
ACCESSION   DAIGWC010000105 DAIGWC010000000
VERSION     DAIGWC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.108"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            725..811
                     /locus_tag="NOB74_002579"
     CDS             725..811
                     /locus_tag="NOB74_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCI1221713.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="NOB74_002580"
     CDS             complement(932..1621)
                     /locus_tag="NOB74_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221714.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="NOB74_002581"
     CDS             complement(1628..1906)
                     /locus_tag="NOB74_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221715.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="NOB74_002582"
     CDS             complement(1866..2780)
                     /locus_tag="NOB74_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI1221716.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="NOB74_002583"
     CDS             complement(2762..3142)
                     /locus_tag="NOB74_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HCI1221717.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3593..3880)
                     /locus_tag="NOB74_002584"
     CDS             complement(3593..3880)
                     /locus_tag="NOB74_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI1221718.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3900..4124)
                     /locus_tag="NOB74_002585"
     CDS             complement(3900..4124)
                     /locus_tag="NOB74_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HCI1221719.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4579..4749)
                     /locus_tag="NOB74_002586"
     CDS             complement(4579..4749)
                     /locus_tag="NOB74_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221720.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4764..5297)
                     /locus_tag="NOB74_002587"
     CDS             complement(4764..5297)
                     /locus_tag="NOB74_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCI1221721.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5318..6160)
                     /locus_tag="NOB74_002588"
     CDS             complement(5318..6160)
                     /locus_tag="NOB74_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI1221722.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1635 a         1152 c         1040 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccaac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag cttactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgccaaaggg gcgcaagctc ccccttgaat ccccctcccc ccccactctc cacaatacaa
     3361 aaaagactag caaatgctag ccactttttg taaagtttcg cttgtttcac cttcggtgaa
     3421 attgttgcaa atcaataatt aggtagagct acattttttt cgttgttcaa agattcttat
     3481 gccatttact attaataaat ctataaatat gataattttt cggctctata atttatggga
     3541 ctgatgaatc agaattgatt cttcagtccc attttcattt tattccaaag aattaactcc
     3601 aaataccaat agaagcccat cctctatata cttgagattc cttactaaca atttcttgta
     3661 attctattaa agatttaggt aatccaaatt tatgttttaa aatatatctt ccaagaaaac
     3721 tacttaattt catactaact tcaccaacac tttttccctc actgatttct ttagaataaa
     3781 gaaagagctt ttcttttaag tcaggatagt catctatagt tgcttcattg tatactttac
     3841 taattgcatt taaaagtttt tcttctttag taaaatccat tataataacc tccctaccac
     3901 taccttctag gtgcccatgg accatgatta acccaaccat taacaataat ttttccaatt
     3961 tctcctttag cttgattcca atctacccaa catttttctt tgttacaata aagaccattt
     4021 ccatagtaag tagctgcatc aacttttatt cctgtaccga tgccagctag acaagttcct
     4081 aatattccta gaataacaca atgttttaat actttctttt tcatgattgt ttttcctttt
     4141 cgttttttta aaattgcttg ttatattaaa taatcttagt aattttatta tataacattt
     4201 tattatataa caatgattaa cgtcataaaa agtagttttg aattcataat cgtttaaata
     4261 aaattataag atcagttatt taaacagcta gtagacataa tgtatatact accaagtaac
     4321 gcctgtacca agggatccag gcgctgattt tgtgaatttt tattggtcta ggttaaaagc
     4381 tctttttaag gcttggtttt ctgcggttgt ttctttctaa ttctttgtga atattgatcg
     4441 gtcatttttt aaatacttgt tatttttgtt tgtgtttgtt atgcttttta catatctcat
     4501 attcatttat tattcttttc taaggttaat aataggataa tctctttcag aaagactgct
     4561 cgtacgagca gtcttttctt atttatcaag tttttctaca aatacttcct cattttgact
     4621 gttgtagtaa ttaggattga gttttagttc ccctttttta tttcctttgt tggccactga
     4681 taataacatt gggctaaagc ttaatattcc tagtaggata gaaccgaata gcaagtgttt
     4741 ttttgtcata agtatttcct tcttcatttc catagctgcc accatttttt ccaattcttt
     4801 gtttgttcgt ccattgtttc tgttgcttca gaaagagtcg ttgaactatt ctctgaagac
     4861 tcttccgtat aagtcaactg cagttgctcc tgaagttttt cgatttgttg gttggcttgc
     4921 agggtgagtt gttgttgctg gtcgagtagt ttttgtatat gagaattatt ttgctctttg
     4981 agggcaagtt gttctcgtaa aaattcattt tcttcacgca actgatctag caacttgttt
     5041 gcaaccacgt ttttgtttgg tatataagca tttttatcgt tgttttgttc atgtttatgc
     5101 aacttatcta gcaacctttg attgtctaag ttgcgagcaa gttgcaatac tccagaacgc
     5161 aatacaacct tataaccacg ctcattttta gctatcatgg aagaatctaa tttttggata
     5221 tgtttcgata ttgcttgcct actcatctta aaaagatctg acaattcctt tattgtaaag
     5281 gtttcttgtg gttgcatact ggttgcctcc taggttgcta ctggaataaa ttatctaaat
     5341 cagataataa actttttttc tctttttccg aaagtgcgga ctctgtttgt ttttcaagag
     5401 cttttttctc tttttctagt tgtttgattt gttggaggag ttcaagttct cgtttcttct
     5461 gtttgatttt ttcgttaatt gttgtagcgg gttcttcgta ttctttttgt ttatcagcta
     5521 aagccaatgc tttattttgg tcttctttgg ttggtgcatg tttgttaaag tcgtctgctt
     5581 ttttgatctc aggtttgaac gtaaattgat agccaataac aggttttccc cgtccttttc
     5641 cgtatttctt tttgattgtt agtcctttga agattgcagt tagttcttga cgtataggtt
     5701 ttataactcg tttatctata tcaggttgct tataactttt aggaatatct aataattcaa
     5761 gaaagtcttc tttggagaaa tatgcgaaac ctttggttct gtattgcttt aacagacgaa
     5821 acatagtctt tgcatagcca ctttgtagct cgttgaattg ttgtaaagaa tagcgtaccc
     5881 actcgtctaa attatttaac aaaggcagtg ctttttcgta aattcgtata tctacgtaag
     5941 gattttctac gtccccgttg attttaaatt ctgtaaacat tacaaacata tcgtaagaaa
     6001 gcccagactc acttctacga ccaaagcgta aagataagat tttttcataa gttgctttta
     6061 aatcttctac aaatcgtaca tttgcagttg ctttgtagtt acttaaatct tttagttggt
     6121 caaacgtaaa acgaactgtc ttatcccctt tttcacgcat tctagacacg atgg
//
LOCUS       DAIGWC010000106         6019 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.109, whole genome shotgun sequence.
ACCESSION   DAIGWC010000106 DAIGWC010000000
VERSION     DAIGWC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.109"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(60..362)
                     /locus_tag="NOB74_002589"
     CDS             complement(60..362)
                     /locus_tag="NOB74_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221723.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(582..948)
                     /gene="ssrA"
                     /locus_tag="NOB74_002590"
     tmRNA           complement(582..948)
                     /gene="ssrA"
                     /locus_tag="NOB74_002590"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1119..1892)
                     /locus_tag="NOB74_002591"
     CDS             complement(1119..1892)
                     /locus_tag="NOB74_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1221724.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2036..2386
                     /locus_tag="NOB74_002592"
     CDS             2036..2386
                     /locus_tag="NOB74_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCI1221725.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2367..3083
                     /locus_tag="NOB74_002593"
     CDS             2367..3083
                     /locus_tag="NOB74_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1221726.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3083..4531
                     /locus_tag="NOB74_002594"
     CDS             3083..4531
                     /locus_tag="NOB74_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1221727.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4602..5111)
                     /locus_tag="NOB74_002595"
     CDS             complement(4602..5111)
                     /locus_tag="NOB74_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221728.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5101..5826)
                     /locus_tag="NOB74_002596"
     CDS             complement(5101..5826)
                     /locus_tag="NOB74_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221729.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2046 a         1050 c         1170 g         1753 t
ORIGIN      
        1 cccttttata agtatggtga taaaatccgt tccgggctac cttttttagg tagcctactt
       61 taatctttat acctttctgg atcaacgaaa gtatacttca aatagtcata acgccgatga
      121 tcgctccgtg cgtctggcac atcagtcacg atatcaaaca aaaaatacac atctttcttc
      181 attctggttt ttgttgccgg aattttaaag tagttcttat tagagtaata gagattgatt
      241 aataagctat cttcgattgc taaaaagaaa acttctgaat cccacacctt ataaaaatct
      301 ttgacaaatc tattcgaagg atcaaattta aaccataatt gtgtttttcc ttccatcaac
      361 ataatgttca cctcaaaaag agtatacgaa ctaatgttct ttttgtaaag taggaatatc
      421 attgataata tggatggaac atatatatta aaaagtgttc tttttgaatg ctattttgaa
      481 tgccattttc attcatttaa cgaaaatctg cgaaaataaa aaatgctcaa acccttataa
      541 aataaggatt taagcatcta gcgaaatctg ctgaaatctc acaatggaga cggcgggagt
      601 cgaacccgcg tccaaacaca tcgccactta aaaatctacg ttcatagtca actcatttaa
      661 ggattcactt tacagcttgc cgagtgacag gcattctgta tcgctagtct gatgttctct
      721 ttttcaactt acagacggaa agttgaaacg tatcccacta aagttaggac ccttactcga
      781 gcacatgggc gatgccgaga ggatctacgc taactgtttt taggcagcta aagcgtaaga
      841 gttgttttcg tttttagcag ttatatttaa ctgtaacgtt tttacgtaga cgtaacctac
      901 gaaacgcaat tcaagctcga ctgtgcctgt cgaatccgta acgtccccgt tagctaacaa
      961 gggttacgtg tatttttcat acaaaattag tatagcatat attgggataa attcaataaa
     1021 aaagcgaatc atatcccatt atttatataa taactgcccc tttcttaaga aaaaataagc
     1081 gattttctta agaaaagagg tagcttcaaa aaaagatctt aaatcagatc aaaatacttc
     1141 aatgcgtgga caattccgcc ttctgtattt ttctttgtga taaaggtaga aagttctttt
     1201 aatccgtcat aggcgttgcc catagcgatt ttgttgtcgc aagcttccaa caaggcaaaa
     1261 tcattcggac catcgccaaa tccaaaagta ggaacttttt ccagctgaag ttctttttgc
     1321 agacgtttga cacctgcccc ttttgagatt cctttcttca ctgtatcgat cgagtaagga
     1381 ccattccgat aaaaagttag ctcaggaaaa tgttcgtgat agtattcgtc acctgattga
     1441 gataagatca gcaacatatt tactgtgttt tctttaaagc ctaaaggatc aatttccgga
     1501 acatctgaat gaatgaagtc gtaagcattg atcattgttt ggctatgacc ggtacaccag
     1561 attttctgat cgttatagta agaaagttca tgaccgttca actgtacatg atcatacatt
     1621 ttttgacatt cttctgaaga aaatgtttga gaatagattt cttcgccgtc tactcgaatg
     1681 aaagaaccat tcatggtgac cgcagaagta atgcccgcat cttccatgat agagtggatt
     1741 tctgcttctg tacgtcctgt agcgatgacg gggagaacat tgttttcttt taatgcgttc
     1801 atagcttttg ccacttcggg tgtgattttt gatttcgcat ctagtaatgt tccatcaaga
     1861 tcaaagaaag tgattgcacg ataatttgac acaaataaaa ctcctttttt attggaataa
     1921 gtttatctta acaaagaatg aacaaaagac aaacctttcg tgaagaattc ctgaacatat
     1981 tggttcagtc aacaatttag agtatactat aagaagagaa tttaggaggg aaagaatgat
     2041 ttttttcagt attggtatct tattcttaat aattggcagt ctttttcgga ttctgccctc
     2101 aaaaggaaat ctgccttttt atgggtatca ttcgcctctt gccgcaaaaa cagacgctca
     2161 ttggcggctg gctcaaaaga caagcggaaa ctggtttttt cttatgggct tactgatggc
     2221 attgatcggc tattatttaa agacatctgg gcatacgaat tattttctga ttgaaatgct
     2281 tctgctagta tttccaatta tgcctatttt tattatgaca gaaaagaaat tacagaaata
     2341 tgacctggaa actggaggga acgataatga atattttaat gattgaagat aatcaatctg
     2401 tttctgaaat gatgcagatg tttttcttaa atgaaggttg ggaagcaact ttcaagtatg
     2461 atggaaaaga agggctcgat gcctttttag aaaacccaca acattgggat atgattacac
     2521 tagacctgaa tttgcccaca ctggacggta tgctagtagg aagagagatc cgcaaagttt
     2581 caagtactgt gccgattatc atgctgacag ctagagattc tgaaagcgat caggtgatcg
     2641 gcttagagat gggggcagat gattatgtca caaaaccttt cagtcctctg acgcttattg
     2701 ctcgaatgaa agctttgcat cgccgtagtg agttggcaga agcaagagaa gaagcagtag
     2761 tttcagatga tcattttgat atcgagacta gtcatttcaa gatgaatacg aaaacacgag
     2821 aagcgtatct ggacaaccgg ccaattgaag gactgacgcc taaagagttc gatctattgt
     2881 ttactttagc aaaaaaacca cgtcaagtat tctctcggga gcagttgctt gaattagtct
     2941 gggattatca gtactttggt gatgaacgga cagtggacgc ccatatcaag aaattacgac
     3001 aaaaaatcga aaaggtcgga ccacaagtca tccaaactgt ttggggagtc ggctacaaat
     3061 tcgatgattc tggtgttgcc taatgcgtta tttgtatcag caactcttag ctttctgcgg
     3121 aatggtcgcg ttgatcttat tgatcgttgg agtttctttt acacaactga caaaacaaac
     3181 gattgaagaa aacaattacc agcaactgtt tggatatgct gaatcagttg aaaagacaac
     3241 gcaaacctat gccgatacgc tcccgcagtt tagtcaagat caggcgtttc aaaatgcatt
     3301 gctgctgaca gagcaagtac tgacagaaca aaatgtgaac tttatattta tcgataaaaa
     3361 cgaacgtgtc atttatccga ctaatacagc tttactgaat tttaccttaa cagctgatca
     3421 atggaaaaat ctgaggaatg gacgtcaaga aaaattcaca tcgaataaaa atattttagg
     3481 acaagcacag gcgacctctt acgcacttgt gccatttaat ttgaatcatg aattctatgg
     3541 agcacttgta gttagtcaac ctgcgcgaaa tatcgataac agcgttcgtc caattacact
     3601 gaacctgttc aaaggattta ttttttccag tatcgttgca gttattgcca gctatgcttt
     3661 tgcagcattc caagttaagc gtatcaatcg gttaaggaat gcgacgaaag aagtgacgaa
     3721 tggtaatttt gatgtacagc tccccgtaca tgacaaagat gaatttgatg agttagcaga
     3781 tgatttcaat aaaatgacga attcattgaa agaatctcaa gcagaaattg aagaacaaga
     3841 aaatcgtcga agacaattta tggcagatgc ttctcacgag atgagaacac ctcttacgac
     3901 aatcaacgga cttctggaag ggttagaata caatgcaatc cctgaaaatc agcgagaaaa
     3961 cgcgattaaa ttgatgaaaa atgaaacaga gcgtctgatc cgtttggtga atgaaaactt
     4021 ggattatgaa aaaatccgta cgaatcaaat cagtatggtc attaaaaaat tcaatggaac
     4081 agaaacattg aaaaatattg ttgcacagtt agaagctaaa gcagaagcag caggagatac
     4141 attgacattg aaagccgttg atgatattga tgtttacgct gattatgacc gatttgtcca
     4201 aatcatggtc aatattattc aaaacgcgat acagtttact gaaaacggcc aaatcacgat
     4261 tactttagaa aaaggctatc ttgaaacgat catcacgatt gaagatacgg gaattggaat
     4321 gtctgaacaa caaatgaaaa gtatctggga tcgttattat aaagtagatc cttcaagaaa
     4381 aaatacaaaa tatggtgaat caggattagg tttaccaatc gtgcagcaac ttgtacgctt
     4441 gcataaagga aaattagaag tagaaagcga actaggaaaa ggaacaaaat tcgctgttcg
     4501 tttgcctgac gtagaaatca aaaaagagta aaaaacaagc ggtataaaag atcatgaatc
     4561 gatcttctat accgcttgtt ttttactata aaatgattga tttagcccgc gggctctaaa
     4621 cgatcaatat aaggactttg agcaatagta gcatcatgag taaagagtaa gataccttga
     4681 ttttcttcat gagctaaata agaaagcaag tggagtagct cttggatctc caatacacta
     4741 agttcatcaa atgtatcttc aataacaata ttgtttcgct tggaaagcaa ggcatgaagt
     4801 aattgcagct ttactttttc aaaagacgtc aactcagctg ccgcacaatt aagcaaggaa
     4861 ggagagatat caagtttttc ttgataggcc aaacgatctt gtttgatttc tttttccggt
     4921 acatccaaca ggacatggtc tttaagattc agataaggaa acatcggcca atttttttgg
     4981 atgatcgcaa aattatccag ttttgcaaca agaacctctt ttttcaagtg ctccaatatt
     5041 ttatgctgtt tttcgagagg acacaaaata acggtcaagt gttcagcatg aatcaaatat
     5101 tcaggtttca ttacgtccag gcctcctact ttgcaaatga tggataaaaa aagtgaaagg
     5161 gaatagacta agaatgagac agcatccact gagcccaata agagtttggg caaatccctt
     5221 aagtatatct gtgaaaaaaa gatcattttg gaaatcgatg gtaaaaaaag tctgttgatc
     5281 catcggaatt gtaagtccgc ttaccgaagt caagatatca cggatatctg gcagttcagt
     5341 agtctttaag acaagaaaat tgatcctttg aagaagcgct tcataaactg actggaagct
     5401 tacgatccac aataaaacca agatacaaca aagaaagaga ggaaagaaca gctgccagaa
     5461 aataaaaagg aataatttgg ttttagaaag accagtcagg tgccaattga tcaattcctg
     5521 cttgttttgc ctgactgaat agtaaaagaa aaagataaaa aggaaggcaa atagaaaaaa
     5581 taaactgaat atgcctttta tataaaatcg gctagctaat tctaaagccg gaagaagctc
     5641 tgtagatgca gaagcgccaa taaatgaaag ccgatcttgg acttgattgg ctaaagccga
     5701 ttgcaaatgg taaagagtca ggcatgctat caataaaaaa gcagaaaagc ttgaaaataa
     5761 acaatagagt attgtctgct ttttgtaata aattaatcga gcagtagcat agcggattat
     5821 tttcatactt ttcacctcta taaaaagtat agaaaatgaa tatgaataaa gtatgaaatt
     5881 cctttagtga aatcacgaat taaaaccaga aaatattttg taaaaagcaa gaggttgtga
     5941 agaagctgcc ctattctatt accgtagatg caagcttttg aacactgttt attcgaaaag
     6001 aggagcagcg acaataatt
//
LOCUS       DAIGWC010000107         5903 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.110, whole genome shotgun sequence.
ACCESSION   DAIGWC010000107 DAIGWC010000000
VERSION     DAIGWC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.110"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(364..1482)
                     /locus_tag="NOB74_002597"
     CDS             complement(364..1482)
                     /locus_tag="NOB74_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221730.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1953..3260
                     /locus_tag="NOB74_002598"
     CDS             1953..3260
                     /locus_tag="NOB74_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCI1221731.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3379..4578
                     /locus_tag="NOB74_002599"
     CDS             3379..4578
                     /locus_tag="NOB74_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCI1221732.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4605..5873)
                     /locus_tag="NOB74_002600"
     CDS             complement(4605..5873)
                     /locus_tag="NOB74_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HCI1221733.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
BASE COUNT         1813 a         1251 c         1058 g         1781 t
ORIGIN      
        1 taaacggtgt tccagaagta gcttcttcgg aaataagccg aaatttcaca aaaatttgag
       61 aaataatttt tgtcaatctc ttcttatttc ttgaagctga ccacttctgt cacaacctct
      121 tccttaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaccaaa caaaaaatat
      181 gaagagctat ttttgcttgc tgttcttatt acttgatgca gaacagcttt ttcacaacct
      241 ctcatacacg gtgtttaatc agctgacctt cggtattagc tcaaaaaacg gaaaaatatg
      301 tgaaactatt tttccgtttg tttctctaat actcaggtca aaacactgat ttcacaacct
      361 cttttaataa cgaagaatcg ctgtcagact cttttcatct ggcgcatctt tttgatccaa
      421 aataaacact ttcccgccat taatgatcac atcatctgct aatgcattca acacttgacg
      481 ccgatcatat tctgtttcag gatcttcacc gaaaccatca gctaagtttg acgtagcgat
      541 aaataaatgt gacacttttc cttctttcgc agctggaacg atatcaacta actgatcgat
      601 gaatttctta tctaagagtt tattgtattc ttttgattct tgagctgcga gttcacttga
      661 cagcttcttc gccccttctt cgatatctct aaaggatagc tgcgcaggag aagcagaaat
      721 cgcaacgtct gcacaataat agggattttt agcaattttt ttgaacatcg tctgattttc
      781 tggtaatgca aataaataaa tcggccattg ttcaggattt tcgaaagaat ccttcaagta
      841 cgtatcaaca gcttggtaat agttgaccca atcgatctct acttcttcat cttttggatt
      901 tacgccatgg aaagttactc catctcgggc tccgcctcct ccattagaag agaagttcaa
      961 accgccacct gtcagttcag atcccaatgc agtaacgaca tcaaccggtg ccccttctgg
     1021 tagagatact tcttttactt gtttgttgct gacctcatac aatttcatgg agtcgcggtt
     1081 caatcccaat aaataataag aatagttgaa ctgcccattt ttgataatag ccagtaaata
     1141 aggaagatca cttacatagt attgatcgtc taccgggata ctcaaacgat ggatataggt
     1201 ctggtcagca gttataatga ccgctacact cgtagttgca ctacgccaaa acgaaggatc
     1261 tcctaacaaa ttttcaattt tttcttggaa cggggaccag tcatgttcgg aatatttttt
     1321 ctcaaaacgt ttctttgctt ctttcgcaaa atttttgaat ttgatctgat ctttttccac
     1381 atcttgatgg gcgacatgcg tattcagcat gatcgtgacg aatggtcctt tagcgccttc
     1441 tgaagtcaat tgtgtcaata attctttatc cttttttgcc ataaacgtac ccctcctaaa
     1501 aaaatcattc ctttgtttct atctaaagtc taccacaaca ctatttttcc atacaataaa
     1561 acgtatctaa aaaaataaaa cggtttctac ggttttaaat ttagctattt ttttaagtta
     1621 tcttcataat ttcctcaatt atttagcccc agtcttcaac tattcttcat gaaatgctga
     1681 taaactaaga aaaagaataa aagaggtgga tcttatgcat ttgattatga ttttcagttt
     1741 attaagtatt atcagtttat ttgctttcag cgcttcccgc ttattagatg cggaaacaca
     1801 gcctattcct gtaaaagtac gtaaaaacga ccgctaaact tccataacgc gcgttcttat
     1861 cctaaagttt tttcagaaac attgaaactc tctcccctct ctgataaaat tttaatttgt
     1921 agcgaaacaa attaattaca aggagatcgg atatgtccat aaaaaaaaca cgtctagtcc
     1981 tattattggc tagtctcatt ctttgccttg cttcttttct accagctgtt gctgtgcaag
     2041 ctgaagatac gttcaaagta aatgcaaaag cagcttttgc tgtagatgcg caaagcggta
     2101 agattcttta tgatcaagat ggagaaaaaa ccatggggat cgcttcaatc acaaaaatca
     2161 tcggtcttta catcgtcctt gatcaagtaa aagaaggaaa actgtcatgg ggtgataaag
     2221 tttcgatttc agattatgca gaaaatttga gtatcacccc agatttatcg aatgttcctt
     2281 tgcataaaga aaacacctac actgtcaaag aattattcga ctctgcaatc atccagtcag
     2341 ccaatgcttc aatggtggcc ttggcagaaa aaatctctgg cagcgaagct aaattcactg
     2401 aacgaatgaa agaacaattg aaagattggg gaatcaaaga tgcaacaatc gttaatgcat
     2461 caggattgaa caactcttat cttggcgaaa accgaccaga aggcactgga gaaaacgacg
     2521 aaaatcaaat gtctgctcaa gatgtggcca tcgttgcccg ccatttgatc ttggatttcc
     2581 cagaaatact ggatgtatca agtactacga cccaaatgtt tggcgaaaat acgcaatcac
     2641 cagtggaaat ggtcaactgg aactggatgc tcccaggatt cgttaattac aaggaaggcg
     2701 tggacggatt aaaaactggt acgactgagc ttgcaggtgc ttgtttcgtt ggtacgatca
     2761 ctaaaaacga tcaacggatc atcactgtcg tattgaatgc ggacggccat gcggaaaacc
     2821 cgagtgcccg cttcaatgaa acagaccgtt tgatggacta ctgctatgac aattggtcag
     2881 aaaaagagct cggaaaagct aacgcaagta ttcctagtct aaaaaccatt gatgtaaaag
     2941 acggaaaaga atcaacagtt cctgttgtgc ttaaaagccc tgtaaaagta tgggtacgaa
     3001 acgatatgga tactggcaaa ttaacgatca cgccaacact tgacaagaag caagtcactg
     3061 acaatgagat ccaagcacct atggataaag gtacaaaaat cggtaccgct acgatcacct
     3121 tggcagacga taaattaggc tatttagaag acaacaatgc accatcaaca gagatcatta
     3181 cggataaaac agtggaaaaa gcgaatatat tcgtgattgg ctggcgacgc gtcgcagaat
     3241 ttttcggcaa cttgttttaa ttgaacaata agaaaaacat ctttccatcg gaaagatgtt
     3301 tttttgcttt ttctagttta aataacagct tttttcatct attttcgtta tactgtataa
     3361 gaaaaaggag ttgaatttat gaatctaacc agagatctga tctttttagt tctctatctt
     3421 attggggtat tctctatcgt ttattggcga aaacagaaga aggatccttc cttgttcttt
     3481 tacggcagta cgtggacatt tacggtaatc ttaacttatt ttgtcgtgtt ggaaattttt
     3541 tattcgacct tttatttttt gattccattg ttgttcttta gtatctttgc tttttcttat
     3601 ttcacagaaa aacgaaggct actgaatggt cttttattca atgttttact catcagtttc
     3661 ggcatctact tgtttgtctt gctgtatgaa acgcaaaata tttttcttgg cggactgatc
     3721 gccttgatca cgattccatt gctacttgtc cttttatttg gtatttatgg attgattgtt
     3781 tttctttttt ggaacggggt cacagtttta cgtagagaat cgcattcatt agctaatctt
     3841 ttaacgttga tactagccat ttttcttaca ctgtttcttg tttttgactt tttcttgtta
     3901 aaatatttgc cgcaatggat aaatgctttg tttttctgcg ttcccctgat cttgatctat
     3961 ctatttatcg tattctacaa ctttttgact gtctcattct tgtatcagtt caaccggcct
     4021 cgatacaatc aagacttcat cgttgtgtta ggcgctggat tgatcaatgg agaaacagtt
     4081 tctcctcttc tagccaagcg aatcaataag gcaattgctt tttatcgggc tcaaagccgt
     4141 gctacattaa atccgcccat cttattgatg tctggcgggc aaggagcaga cgaaaaagta
     4201 ccagaggcca ttgcgatgaa acaatatgcc atggaacaag gaatccctga aagagacatt
     4261 cttgtcgaaa ccaattcgac aaccactttg gaaaacatgc tctattcaaa ggaaatcatg
     4321 gatcagcaaa tgaaagggcc ataccgcgcg atctttagtt ccaacaatta ccacattttt
     4381 agagccggtc tttatgcgcg gcaagccaaa ttgaaagcaa atggtattgg tgcaaaaaca
     4441 gctttctact acttgcctaa tgcgttttta agagaatacc tcgccatctt gatgatgaac
     4501 aaaaaaagac atatgatcat ttgcggattg cttttcgcag gctccgcatt cttatcgctg
     4561 attactttac ttttctaaaa aaacaaggtg tgacaaaaca tatgtcacac cttgtttttt
     4621 tctttcattc tcttaactat tggcaaaaag agtatccctt ttttgaccgc tacttgctga
     4681 gcagaataaa taccgctgtt gcctgaacac ataaagctga tcaagcagat cataaagaag
     4741 tatactgccg cttgtgaacc gaacaattcg atccccatca caaagcaggc aatcggtgta
     4801 tttgtcgcac cagaaaatac tccgataaag cccaatcctg caagaaaagg aacagaaaca
     4861 tggagcaaag gcgctagtgc tgcaccaagc gttgcaccaa tttcaaacaa tggtgtcact
     4921 tctccccctt gatatcccgc gcctaaagac aaaactgtga agaataactt cccaataaaa
     4981 tcatagacat gtgcctgtcc attaaatgat tcttgaagta acggaagact caatccgaga
     5041 taacgttgtg tttgcaaaat caatgctgct gccacaacta cagctccacc tatcgtattt
     5101 cgacaaacag gatgaggaat ccattgtgca tatcgcgctt ttaaaaagac gatcgaacgg
     5161 ctgaataccc aaccaatcaa accaaaagca atcccagcaa caaaaacttt gaagaacagc
     5221 aacatactcc attcaggaat cacacccatt tggtaatgta gatgagaaac accatagctt
     5281 tctgtcatga aatttgcaaa cagtgcagca aagaagctag ggaagatcgc ttctgttcgg
     5341 actttcccga ttgccaacac ttctaatcca aataatgttc cagctaaagg tgtgccaaat
     5401 acagaactaa aacccgcact gattccactg ataatcaaga tttcccgttc tgatttatcc
     5461 aatcggaaca aacgtgccgt attatctgct aacgctcccc ccatttggac tgctgttcct
     5521 tcacggccaa cagatccccc aaataaatgg gtagttatgg ttccaaacag tgtaagtgga
     5581 ataagccgca acgggatttt ttcttctcca ccatttcctt gatcgatcac taagttgttt
     5641 ccacgactag aaagtccgcc gtgatacgca tagagataag caaaaagcgc accactaact
     5701 ggtagtagac aaaggagcca aggatgtgat agtcggatat ctgtcacaac tgtcaggcta
     5761 tttaagaaaa aagcagacaa gctccccatg aatataccga gaatcgctgt gatcaccagc
     5821 cacttcagca tatacactaa aatgcgtact ggactcggta attgtttttc cataaaaaat
     5881 tcctcctcaa taaaaaaacg cct
//
LOCUS       DAIGWC010000108         5874 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.111, whole genome shotgun sequence.
ACCESSION   DAIGWC010000108 DAIGWC010000000
VERSION     DAIGWC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.111"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            641..1375
                     /locus_tag="NOB74_002601"
     CDS             641..1375
                     /locus_tag="NOB74_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1221734.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1391..2560
                     /locus_tag="NOB74_002602"
     CDS             1391..2560
                     /locus_tag="NOB74_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1221735.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2576..3571
                     /gene="lacD"
                     /locus_tag="NOB74_002603"
     CDS             2576..3571
                     /gene="lacD"
                     /locus_tag="NOB74_002603"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI1221736.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3650..4576
                     /locus_tag="NOB74_002604"
     CDS             3650..4576
                     /locus_tag="NOB74_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HCI1221737.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     ISKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4595..5845
                     /locus_tag="NOB74_002605"
     CDS             4595..5845
                     /locus_tag="NOB74_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1221738.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1967 a          955 c         1203 g         1749 t
ORIGIN      
        1 gtttgaaaaa tgctatttcg aggtagaagg atattatata agcacggttg actaaacgaa
       61 gtgataataa aaaaagttat tcaagaataa gaaaaattat gatacgaatt cagataaact
      121 ggagaataca gagaccttta aaagggataa gaaacaacat aaattcctct taagagagaa
      181 cgaaaggaca aagccagcaa cttgatacac gagctagtat tagaggaatt tattctcata
      241 gactcccttt tgaatacgtt tcaactttaa ttttcatgtt cataaatgat ttgaaaccaa
      301 agcaaatgcg ttgcactttt cctccgtctt ccgaaaatcg ttcaattcac tggtaagtag
      361 tcatttgata gtttgaggca aattgttgat tgatgaaggg taggagctaa aaaaagatac
      421 cagttgaaga gagaaaaaga aaaaaataga gggtgttctt gaatgaaaaa agttggaaaa
      481 ttatttttca tttcctttta ttcctattaa agtcagtgat gtcaatcata ttaacaagac
      541 taaaaatgaa aataaaaaaa agattgttct tagtattgac tcataaaaaa taccactact
      601 atacttacat tgtggttata gccagttagg agagacatcg atgcaaaata cctttcaatc
      661 aaaatcactt tattatcagc tggtagaaat attgaaacaa cgaatcgaaa acagtatggt
      721 cgctcatgac aagctgccat cagaaagaga gttgaccagt ttttatggcg ttagtcgcac
      781 gacggtgcga ctagcattgc aagaactgga aaaaatgggc tacatttatc gacaacatgg
      841 aaaaggaacc tttgtttcgg aattaaggac aaatgcgact gatctagctg gcgcatatag
      901 ttttaccgaa caaatgcggg caatgggcaa acatcctgaa accaagatat tggccttcaa
      961 gaagattgaa gcaactaaat atttagcgag tcatctgaat gttcaactag gtgagccttt
     1021 atttcaatta gaccgattgc gcttagctga tgatttgcca atgatgatcg agaaatccta
     1081 tttgccagtg aagctattta tgtccctttc tcaagaaatt ctatttctga aacctttata
     1141 taatttgttt tcagagaatt tcaatcaaat cgtacggttg gctgacgagg aattttatgc
     1201 cagcattgtc cagaaagaag atagtgagtt gctaaatatt ccagaaggat caccagtgct
     1261 ccatttagtt cgctcaacct ataatctcga gaacgaagtg attgaattta cattaagtgt
     1321 agcgcgggct gataaatttc attataagat caggcatctg cgttccacta actgaattgg
     1381 aggaaagaaa atgtttatgt tctcaaaaga agaactacga aagctaggag cagaaaatac
     1441 tacccgagaa attcgacagc aaccggaact gtggcatgag acgtttgacc gttatcaaga
     1501 aacagttgca gatttagatc gtttgtttac ggatgcgaaa caacatgctg gagagcgacc
     1561 aatccgagtc atttttacag gggccggaac ctcgcaatat gtgggagata cactaattcc
     1621 gtttcttact agtcaaggaa atacgaacca gtttattttt caaagtattg gttcgaccga
     1681 tatcgttgct acgccaaaag aatacctgat tcctgatgag acaacgatct tggtctcatt
     1741 tgcccgtagt ggaaatagtc cagaaagtct agccgcagtt aagatggcca atcagctggt
     1801 caacaagatc tatcatatcg tgatcacctg tgcaccagac ggattattgg ctacacaaat
     1861 gcctacaaaa aaagaaaatc tagttttact aatgccaaac aaagccaatg acgctggttt
     1921 tgctatgaca agcagtttca gctgtatgac gctgactgcg ctacttattt ttgatcaagc
     1981 aagcaatcag caaaaagaaa gatatgttca tcaattaagc cgactaggag aagaagtcat
     2041 ccaacgagaa tcagagatcc aagggtatct ggcatcagac tttcatcgca tcatttactt
     2101 aggttcggga agcttaggcg gattgactag agaagcgcaa ttaaaagttc tcgagttaac
     2161 tgctggaaaa atcgcaaccg tatttgatac atctttagga ttcagacatg gtcccaaatc
     2221 ttttgtcaat gagcaaacat tggttttcct gtttgtcagc aatgactcat atacgcagaa
     2281 atacgatgta gacatgctgg aagaaatcaa aaatgacggt attgcccaac gcgttgttgg
     2341 aattggtcaa aagggttcat tgtttagtgg tgattccttt gaattagttg cagattcgtt
     2401 actgccggat ggctatcttg ctttagcaga tatcatggta gcccaaacga tcgcattact
     2461 ttgttcggtg aaggttggta atacaccaga tacaccatcg ccaagtggaa cagtcaatcg
     2521 tgtggtcaaa ggcgtaacga tttatccata tgaaaaatag gaaagagtgt gaagcatgtt
     2581 agaatggtcg gaaaataaaa gacaagcaat ggaacgtcta tcgacgccag aaggcattat
     2641 taccgctttg gcgatcgatc agcgaggcgc gctgaagaaa atgatgtcgg ctttagggat
     2701 ggaagcgaca aaggaaaaaa ttgagcagtt taaaacacta atttcccaag aattgactcc
     2761 ttatgcctca gcaattttat tggatcctga atacggactg cctgctgcac agaagcgtgc
     2821 agcagcgagc ggtctgctgt tggcatatga aaaaactggt tatgatcaaa ccgtacccgg
     2881 ccgcttgccg gatctgctgt cggactgttc agttctgcga ttgaaagagt taggtgcgga
     2941 tgcggtgaaa tttttactgt attacgatta tgaagaagca gaggaaatca atcggcaaaa
     3001 gcaagttttt gttgaacgaa ttggaagcga atgcatggct gaaggactgc cattttattt
     3061 agagttattg tcatatgatg ctaaaaatgt agatacgaaa tcgctttcct atgccaaagc
     3121 aaaaccgcgc aaagtgatcg aaatgatgaa agaattctcg aaaacccagt ataaagtaga
     3181 tgtcttaaag gttgaagtac cagtaaacat gtcatttgtt gaaggaaatg caacagggga
     3241 gatcgcctat acacgtcaag aagctgccgc ttattttaaa gaacaaagcg atgcaacaga
     3301 tttgccgtat atcttcttaa gtgctggggt atcagcggca ttattcatgg agacattgcg
     3361 ttttgccaaa catgctgggg cacgattcaa cggtgtactc tgtggcagag caacttggaa
     3421 agatgcagtc gctcctttcg ttgaaaaagg agaagcggca actttagaat ggctgacaga
     3481 acaagggaca caaaacattc gtcaattgaa tgaagtgata agagaaactg ccatcccatg
     3541 gtatgagaaa gtaagtgaaa gcacttgtta atgtttctaa tatattagta gtgataagag
     3601 atatgtgtga ttataattta tcattattga aactgggagg atattttata tgaataaaag
     3661 attgttagat tattcagctt cagatttttt gaaagctaag ccgatggaat taaagcaggc
     3721 aattttggct tctgaaggta gaacaattat ggcagaaaat gtgccaagta gctgtcctta
     3781 catgggaaaa tcagtgacaa atgcagaatt ggagagagct gctggagctg atttaatttt
     3841 gtttaatgca ctagatcttt ttaatcctca aatttcaggt gtacctttaa ctctaaaaga
     3901 gaatccaata atctggatta aaaaagcttt aggaagagct attggtgtaa atttagaacc
     3961 tgtagacaaa gaagttttga tgagtgaaaa tcgaactgaa atttcaagtg gtagaatcgt
     4021 ttctcctgag actttaaaaa aggcaaatga attaggcttt aattttattt gtttaactgg
     4081 aaatccagga acaggagtat ctaatagaac tattgagaaa gcaataacaa tatccaaatc
     4141 aatttttaat ggattaatta tcgctggaaa aatgcatggt gctggtgttg atgaaccaat
     4201 tatgaactta gatatagcaa aaagatttat taaaacaggt gtagatattt tattagttcc
     4261 tgctccatac actgttccgt atttcatgga aagtgatttg cgaggaatcg ttgattatat
     4321 aaaagatttt aatagaaata aatctattga ggaaaaagtt ctagtactaa cggctaatgg
     4381 aacaagccaa gactcttctg accaagaaac tattaaaaaa attgcattag catcaaaagc
     4441 atgtggagct gatattcaac acatagggga ttctttaaat ggtatttgtc ttccagaaaa
     4501 tatttttgct ttgggtcaag caattcgggg atatcgtcat caaattatta tgttaggaaa
     4561 atctaattat cgttaattaa ggaggaaatg aaagatgatc gacaaagttc aaaaaatagc
     4621 tgcaaaaatt agtaatcaaa gacatctact agctttaaga gacagcatgg ctgcagttat
     4681 gccattaatc attattggtt ccttttttat gttattagca aatttcccga tagaaggatt
     4741 tacaaaatgg ttatctgaaa ttggagtaca atcctttttg aacaaagcat cagattcaac
     4801 atttggtatt attggattag ctgttaccta ctctttggga cacaatctag caaagactta
     4861 tggtgtagac tcattatcag caggattatt atctttgagt ggatatgttt tacttacacc
     4921 tttattggat gcagatggtt ctataggatt tccaacaaaa tactttggta cctcgggtct
     4981 ttttgttggt attattgtag cacttgtatc tacagaaatt ttccggtggt ttgtacttaa
     5041 aaatattaca attaaaatgc cggcaagcgt tccaccaaat gtaagccgag ctttcgttgc
     5101 tattattcct ggcttttttg tcgttctact atggtttatt gttgttgtaa tttgttataa
     5161 acttggaatt gaaaatgttc atgctcttat tgcagataca ctcgcaaaac cactatcttt
     5221 actgacgaaa actttaccag gaattatatt ggttatactt attcaatgtt tcttttggat
     5281 gtttggtatt catggtgcac aggtaacggg gccaataatt gaaccgttat tattgcaaaa
     5341 ctctgatgta aatagaattg cttatcaagc tggaaaagaa cttcctaaca ttataactta
     5401 tgaattctta tataactttg ttttttctgg tggtgcaggt tgtttatttg cacttgccat
     5461 tttaacattt ttcttttcaa agagtcagga aaataaaact ttaggtaagt tatcaatcgc
     5521 tccagtaagt tttcaagtag cagagcccct tctatttggg tttccaacta tattaaatat
     5581 aaaaatgtta attccatttg taactgcacc agtagtaaca acattaatta cttatttttc
     5641 aatgagtatg ggattagttg caaaacctgt aggagcaaca atcccatgga caactccacc
     5701 gataattgcc ggatttttag cttctggtgg acgaataagt ggtgcagtga ttcaagtaat
     5761 aacaattgca ataaatgttt tgatatacta tccattcttt aaattagatg ataatgccaa
     5821 gctaaaaagc gaaaaaaatg attagaacta cctatatgtt tctaactgta gtta
//
LOCUS       DAIGWC010000109         5830 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.112, whole genome shotgun sequence.
ACCESSION   DAIGWC010000109 DAIGWC010000000
VERSION     DAIGWC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.112"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..115)
                     /locus_tag="NOB74_002606"
     CDS             complement(<1..115)
                     /locus_tag="NOB74_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI1221739.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="NOB74_002607"
     CDS             246..698
                     /locus_tag="NOB74_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221740.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="NOB74_002608"
     CDS             712..1401
                     /locus_tag="NOB74_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221741.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="NOB74_002609"
     CDS             1526..3877
                     /locus_tag="NOB74_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HCI1221742.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="NOB74_002610"
     CDS             3957..4352
                     /locus_tag="NOB74_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221743.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="NOB74_002611"
     CDS             4677..5294
                     /locus_tag="NOB74_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1221744.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="NOB74_002612"
     CDS             5335..5634
                     /locus_tag="NOB74_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HCI1221745.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
BASE COUNT         2033 a          785 c         1173 g         1839 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa
//
LOCUS       DAIGWC010000110         5779 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.113, whole genome shotgun sequence.
ACCESSION   DAIGWC010000110 DAIGWC010000000
VERSION     DAIGWC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.113"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..813
                     /locus_tag="NOB74_002613"
     CDS             <1..813
                     /locus_tag="NOB74_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HCI1221746.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVHATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="NOB74_002614"
     CDS             807..1229
                     /locus_tag="NOB74_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221747.1"
                     /translation="MVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2363..3331
                     /locus_tag="NOB74_002615"
     CDS             2363..3331
                     /locus_tag="NOB74_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI1221748.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            3341..3829
                     /locus_tag="NOB74_002616"
     CDS             3341..3829
                     /locus_tag="NOB74_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCI1221749.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            4125..4406
                     /locus_tag="NOB74_002617"
     CDS             4125..4406
                     /locus_tag="NOB74_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221750.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            4408..4824
                     /locus_tag="NOB74_002618"
     CDS             4408..4824
                     /locus_tag="NOB74_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221751.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            5438..>5779
                     /locus_tag="NOB74_002619"
     CDS             5438..>5779
                     /locus_tag="NOB74_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HCI1221752.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2157 a          982 c          941 g         1699 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcctttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tctctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgtgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acatgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaagtagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaact cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctcgaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaagc
     1441 cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca aacgatacgt
     1501 cctatggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat ttggctagca
     1561 atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt cgagtgagcg
     1621 aatccaaatt tgcaactctg aagctttgca aatgagtgtg ccggcttccg taaaagtcta
     1681 ggtaacatta gtcgatatat acatagggct ctaatttgcg ttttaaggcg ttttaaacgt
     1741 tctggtatgt aattatacca aagcgacttt aaaacgcctt aaaacgaatt ttagaggttc
     1801 tgtagaacgt tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg ctttaaaaac
     1861 aagataaggg attttatcta gacttgtctt aaaacgccgt agatgagcgc tcagagcttc
     1921 taaaaggact ccttacgaac tgtttttaag caaaggagcc tttaggcgac tgcgcagttt
     1981 aatgtgagag cgtagcgatc acacctttaa agcgaccgta gggagcagat tcccagttta
     2041 ggaaatttcg cgaacctgtt tggagaaaaa aagtaggaaa attttaggcg ggaaattttg
     2101 cccccctctt ttataatctc ttttataacc tctttttaaa cctctttacc gtcggctgta
     2161 tccttactct cccaaggtgt gcagaatctt ttaggggtct ttttgtctgt ttttaggggt
     2221 ctttttgtct gtttttaggg gtctttttgt ctgtttttag gggtcttttt gtctgttttt
     2281 aggggtcttt aattaggggg ttgaccccca ttagaaagct ctttataatt ttgttaagta
     2341 gttaatcttg aaggaggatt ttatggcaaa tgaaattgtg aaataccacc atgaattaaa
     2401 tacgattcct ttacgcaaat ttacgtcagt agaaatgaat ttattcttct ctataatatc
     2461 tagaatgcgt gatgtaggcg ataaaaaagt acaatttaca ttcgaacaat taaaagattt
     2521 aagcaattat aaagcaactg caaatgttcg attcatagat gatttagaaa caacgtatga
     2581 caaattaatg gatttacgtt ttggtagaag aagtgctgac ggtttgcaac gtgaacgatt
     2641 tgttttattt aatcaattta aaatcgatgg aaaagctgat attccttttg ctgaaataca
     2701 agtccatgag aaagccttac ccttacttaa taatcttgaa gaatgggttc gatattctct
     2761 ccaacaattc aatgaattag aaagcagtta ttccaaaacc atgtttagat tattaaaaca
     2821 atacagaacc aaaggaattg ccaatttttc aaaagaagac tttcatgaat tacttgatat
     2881 ccctaaaagt tatagagaaa gtgatataaa taaaaaaatt ataaagccta ttcgccaaga
     2941 actaaccgca atcttcaaag gtttgacaat ccaaaagaga tacggaaaag gacggggaaa
     3001 gcctgtcatt ggctatcaat ttacatttaa acctgagata aaaaaatcag acgactttaa
     3061 caaacatgct ccaaccaaag aagaacaaaa taaagctttg gaactagcta atcaacaggt
     3121 tcaatctgaa aaagaaccta cttcattaca agaaaaaatc aaagaacaaa aacgaaaatt
     3181 agaactttta caacagttag cagaattaga aagaaaacaa aataccccaa gtaagaaaat
     3241 taacaaacaa atagcagata acaattccga tattacccca gaatttaaag aaaacttact
     3301 agataatctc caaaacttat ttaaagaata aggggttttt atgacagata aaactatcaa
     3361 agaattagca gatattctag gtgtttcaaa agataaagtg aagtatcaac tgaggaaatt
     3421 acctagtaat tttacctaca aaaaaggaaa tattacctac ctgaaaaaag aagcagtaac
     3481 aacaattaca aaggttttat caggtaatga atcgggtaac ttacctagtg aattacccga
     3541 ttcattacct accgattacc tactcaagga gattgaaact aagaataatc atattgaaga
     3601 aaaagatagg caaattgaaa aacttcaaat agctttagaa acgcagcaaa aattactcga
     3661 ccagcaacaa caactcaccc tacaagccaa tcaacaaatc aaaaaacttc acgaacaact
     3721 ccagctaacc tatgcagaag aatcttcaga aaaagaaccc ctttctgtta ctgaagaaac
     3781 tcaaaaagga caaaacaagg agaaaaaatg gtggcaattc tggcaataac ccaacaattt
     3841 ttatgaataa aaattgttgg gttactttct ttttttgctt ttacaagcat agcgacatga
     3901 tctcacgtcg ctatttttta aagagcataa ggaaacgcgg tatcactttc ttacgaaagg
     3961 tgctaggtag gctgtgccta ccacgtttct aagaaaaaaa tttgctatca ctttttcgtc
     4021 attgtggata gcttatgtat agtgtttcgg caaaaaacag ctatacaaat actatatttg
     4081 tatgatatac ataaattata cacaaatgcg aaaggaattc ttctatggac attttagttc
     4141 ggaatattga tccaaaagtt atttcagaaa tagatagacg ttgccaagaa ctcacaacaa
     4201 aaactggcaa aaaatggagc cgtaatgcgt acctaaaagt tctaatcgaa aacgattttg
     4261 accaggcact taggcattac aaaaaagatc aattcgattt attactcgaa aaatttatcg
     4321 atatacaagc aaaaaatact gaaacattga acgactatgt tcatacaaac aaccaactca
     4381 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgttacc
     4441 ctttatccca gtcacattga cgttttagat tccatcatcg aaaaaaatcc agatatcaat
     4501 aactactcgg aagccattcg ttttctatgt atgagttatg aacctaatac taatacgaca
     4561 actaccagca accaagcaaa actaaatgcg atgggaaaag aaatttctat tatgtccgaa
     4621 atcattgcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4681 tctaaagtat atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ctcccgacga
     4741 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacat tcacttctag aaattttgac
     4801 ccaacaaact ttctaaaaag atgaaaaaga aaccgaaaat tttttctatt tctcagtttc
     4861 ttttttaggg ggcagtcttc cagcaagatt tgcaagttac cggtaacttg cacaaaaaaa
     4921 gaaaaatccg cttgtgcgaa tccttctttt tgcattttgg ggcgctgccc caatctccaa
     4981 atatcggtta tttaatagcg tggtaactca aaaaaataga acgtactctg aaataaaaaa
     5041 agactgctct aacgagcagc caataaaaaa taatgagcgt ttattcttga aaaagcagcg
     5101 cgcttatgaa gcgctgccaa aaatttacca tattttatga aaaataacaa gtttctaaaa
     5161 aggaatcggt taagattcac aaagaatcgt aaacagacaa tagcggaaaa tcaagcttcc
     5221 gaacgtacct tttagctaga ccaatgaaaa atcacaaagt gagcccctgt atcggttgat
     5281 acaagggcta cttggcatac tatacattat gttaactaac gctataaata acgattatgt
     5341 tcccaaaaca atattttatg aactataaca aaaatttgtt atcgcatatt gtatatttta
     5401 attataggtg tataccactt aaatttaaca caaaggcgtg attattttga aacccaaaaa
     5461 gaaaatttat ctaggtctcc tcttttcctt gatgattgga atttttagta taggaattac
     5521 aaatacctat gcttcagaaa attctaattt caatatcaac tcccaaccaa ttgaagaaca
     5581 agcaattaat tttgcgaaaa ctgattttga acactccata acttcaattc ttttaatgga
     5641 aaataacacc gaaactgata ttaactatac tcttggttcg ccatttaaaa tgctcgatgg
     5701 agaaaatacg gcaaatagtt ctattttctt tccagtattt tcagacgctg ataatacgat
     5761 taaatatatt tataccgtc
//
LOCUS       DAIGWC010000111         5768 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.114, whole genome shotgun sequence.
ACCESSION   DAIGWC010000111 DAIGWC010000000
VERSION     DAIGWC010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.114"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(1013..1303)
                     /locus_tag="NOB74_002620"
     CDS             complement(1013..1303)
                     /locus_tag="NOB74_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221753.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1705..1941
                     /locus_tag="NOB74_002621"
     CDS             1705..1941
                     /locus_tag="NOB74_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221754.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1948..3900
                     /locus_tag="NOB74_002622"
     CDS             1948..3900
                     /locus_tag="NOB74_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCI1221755.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3972..4469)
                     /gene="dfrG"
                     /locus_tag="NOB74_002623"
     CDS             complement(3972..4469)
                     /gene="dfrG"
                     /locus_tag="NOB74_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCI1221756.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4796..5488)
                     /locus_tag="NOB74_002624"
     CDS             complement(4796..5488)
                     /locus_tag="NOB74_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI1221757.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1893 a          996 c          917 g         1962 t
ORIGIN      
        1 tacttgcaaa gtaatactac aattcctaac ataatcgtag aatttaataa tttccatagc
       61 ataaagtgtt tagaaaagaa cattaagaat agttctataa taattcttga actccatgtc
      121 ttataatgtt ctatcgaagc acccaaatag ccaagttcat ctaatctact tgcataaact
      181 acgtcatccg ctctcatagt cggcatatac atattaaaga gtaaaaagat accccaaatc
      241 cctattagta acaagatcag ttctttgtta ttcgttattt ttctattatg tttgttcatt
      301 tttatactcc ttcttatatt tcctaataga gtataacata gctttaagca ttacttaaag
      361 ataacttaaa agttatcttt taaatactta attgttaaat accttatttg atgcaaaaga
      421 aatctacgat agtcaacaaa aaaattttca ttatatccag aaaaattttt cttagttaag
      481 gacctatgga ttgcagtaat gcagaattcg tcgaataaac tgccaaagac atacaatcat
      541 attgctttta aaattgacga acaagatata gattcgtttg tctcaaaaat ccaaatgtta
      601 ggtttaactg tcgaaccagg acgttctcgt gtgaaaggcg aggcttcttc aatttacttt
      661 tacgactatg ataatcacct cttcgagtta cataccggta ctctccagga acgtttaaaa
      721 tcctacaatt ccactacctg agactagtaa tgactagtct ctttttatgg cctctgatcc
      781 ccccattgag cgaatactaa tagggcttcg aattgatctg ttcaatcttt aagcaatatc
      841 cctcaaatga gtttggaaag tttagtgatt catcacaaat acttaaatac atgtagttat
      901 atatagattg aggttcttgt gagcgtatgc tcgtgtgggt tcaaatccca tcgtctgcat
      961 ccatctttcc aaaacaagcg gctaggacat ttttgtctca gccgcttgtt ttctagttta
     1021 ttctttcatc ttgtcggacc ttttttcttg ggtatagact tttctcatat tctaccacaa
     1081 ttttgggttt ccctaacaca tgataggatc tcacaacaaa ttgctttcta ttattataat
     1141 aacctgtaac gactaacttc atcccttcgt ctacttcagc taggaagttc aaactatggg
     1201 aagcaatcaa acaattgacc ccatttaaac tgaaacggat caacggtctg gcactaactt
     1261 gcaaagtacg gatcttatct actgttccat attttttctc cataaccttc acctcaatac
     1321 cattatacga acatacattc cctttgtaaa gaagaaactc tgttttatct ttttgacttt
     1381 ttgtctatta cctttcttaa aatcatattg gcacttcctg cgaagatgaa ggacatgtac
     1441 taaaaaaaag aggcagcagt atagatttaa gtagttcagt tttggagtac aaaaagtgaa
     1501 aatgtaaacc taaatgagta tcaaattgca actgaatttg atactcgttt tttattgtta
     1561 aatcaacgtt tgttgttaat ttacaccaca aaatgtaagt taaaatgtat ataaaaatgc
     1621 gaacgtgaaa taattattgt aggaatgcaa attggtgtgt taaaatggtt acaatttact
     1681 aagcaaaaag gggtgcattt tcctatgcaa tttcttgagc caaaaaataa gaacgctaag
     1741 tctgtggatt gggaaatatc agagcaagta agggtgatag ttaagcaata cgctgaatat
     1801 gcagagcgta ctgaaagcga agcagtggat gaattcttat tgaacatttt agacgataag
     1861 aagtttattg aatggattgc caacaagcga agtaataagc ggattgttga aaaaatgggt
     1921 atcaaagata gagtgggttg atagacaatg accaagctta aaagattagc cacgaaggaa
     1981 gatgaaattg tagatgttaa aattccgatt tcaaacgaag aattaaaaga tagggctaaa
     2041 caatatgatt tattaactcc aaaacgattt gcaacaaggt ataacaaaat gttgttcttg
     2101 ccaacgtctt ttaaatggaa cggttctgaa tatcccattc aatataatta ctgcatcaat
     2161 ccgttttgtt gtaattttgg gaaagaacag cacaaattca aagatgtaaa agggaaacca
     2221 agtcgatata aaatgactgg tagttccaaa gataaaggtc ataaaggtat gtactgcaat
     2281 gacaatccta ttggcagagg tgtatcgcaa aactgtacag taaccccttt atctaattgg
     2341 tctgttgttg aagaaattaa acgccttata gaaatcaata gcatccaaga tgttgagcca
     2401 gattatcaat ttcataaaga aggctgctcg gaagaagaat caaccccatt caatgagccg
     2461 aagcaatttt acaaaagggg gaaaagtagg ggcaaatctc aacgctatca atgtaaggcg
     2521 tgtaagaagt tcactaatgt tctaccaaaa agagaagaaa ccactactta tcaccaacaa
     2581 aagaacacca ttcttccaat gttcgctaag atggttgttg gaagggtttc agtcagtcgt
     2641 acttgtgata ttttaggaat tggagttgga acctactatc ataagctgga gtggctgtat
     2701 aggcgttgtt tggagttttt agaacgatat gagacacaac cccttcaaac aaagaaattt
     2761 aacgagatgt ggcttaatac ggacaagatg cactactacc taaataacgt ccgtaagaaa
     2821 ggacaaggtt caaagaaata tacggggttt gaagacctta atatgcaaac gtatatagtt
     2881 gtatctgctg aggtcttatc aagatatgtg ttccgttctg atgttgccta tgattggaat
     2941 atttcaatgg atgaattaaa tgaagataca agaaaattca aagaagacca tctcaatact
     3001 tttagtcgta aaaatgatag gttagattgg tcttattatc cacaagaacc atccgctaac
     3061 gatagcgaaa ataggaatgc ttatcttcac gaattaggga aaattactaa taggagtaga
     3121 tttgtcgatg gtttaaatgt tgatgctcct tatactacaa ctgctcacta ttggttaatt
     3181 aaacaaatgg ttaatgccga cgaatggcga atgattagtg atgatgactt ctctattaga
     3241 aacgcctttt atagagtatt cacgaaagaa ttaaggttga gcgatgcaca tcattttatt
     3301 tgccaagtta acaagacgaa aagcagaaaa caatgcttaa aagaattcgg acaagcaaaa
     3361 gcagaactgc tcgattgggg agatatcaga ggattcaaaa caaagtttct acggactttg
     3421 gcatctcatt atctaactga attactaaca agtcatcaat tccacgaaga ggctattagt
     3481 aaagatggag aaagatatcg caaatatgcc gataacccta tcaaacatcc attagccact
     3541 aaggataaag gattttattc agttgattgt agaacggatt tatctgctct ggaaccaaac
     3601 gaaatcgcaa agatgctatt aaatgttaat gaccattcga ccaatagctt tattcaacag
     3661 ataagacgtt atatatcatc tcttgaaaga ccattaacaa cagctcgtgg tgataagaag
     3721 agctatattt acgctaactt caatccgaag tatgctcaat ttgcgattac aattctaaga
     3781 acttactaca acttttgtcg cccttttaaa tcagcggata aaaaggtttt gacacctgct
     3841 caaagattag ggattacaga taaacaattt gattggaaag atataattta tttcaaatga
     3901 caaaaagagc ttggagtaat cccaagctct tgtgctttat ctttactgtt cttcttcaat
     3961 taacgcaccc gttaactcaa taagtttttt ctttcatata catgaaaata gtagttatac
     4021 ggatttttat cattctttat ccctttttgg gcaaatacct cattccattc ctcataattc
     4081 acttctggaa aaaaagtatc tccttcgaat tcatgatgta tttttgtgat gtacattttc
     4141 tcaacataag ggaaaaacaa attataaatc tgttctcctc cgaaaataaa aatttcttct
     4201 tcgtttttac ataactcaaa aacatcttct attgaatgaa caatttcaca accattaaag
     4261 gtaaacccct tatctctcgt cagaataata tttcttctgt caggtaaggc tcttccgatt
     4321 gattcaaggt tcttcctacc taatattatc ggatgtccct ttgtagtatt tttaacatat
     4381 tcccagtcct tgggaatcct ccaaggaatg tcattctctt tgccaatcac tctattctta
     4441 tccatcgcag caatcaaaga aactttcatt tataacacag cctttttaac taatttacca
     4501 tctaatttct tatttctatc aaaaaacctt ttctcattat cctgcccgtt agttgaataa
     4561 gcaatttttt ctataagtta tattatcata ataccacaaa atcacaaatt ttcattcaat
     4621 tatcattttc aattgcattt tataaatcat tttgtatgta atttggtatg taagttaaaa
     4681 tgaaaaaagt agtccatttt gaagtacatt ttgtcatttt gtactccaaa actgaactac
     4741 ttagtataga ttactgttgc ttctttacta atttaggttt acttgttaag aaagattatt
     4801 tacgcaaatg ttcttcaaca atttgctgag atttatcagc tgtatcttcc acttcatctt
     4861 ttgctttttc taacttttga atatattgtt tcaagcttga gttttcagca gttgcttcgt
     4921 ctaatttctt ttgtgtatct gttaactgag tttctacatt tgttttttct tgtgtcagtg
     4981 ttgcgatttg ttgattcaaa ccatttacag tattttgtaa ttctgaaagt tttgcttgtg
     5041 cttcttgtag tcttgctgtc caatctgcat tcagatgatt gatttcatca tttttttggt
     5101 tgatctcatc tagtttgaca ttgatttcat tttgtttgct ttgtagttgt gcatccttgc
     5161 tgactaattg actttctaag ttttgttttt ctgctgccga ttgatttttt tggttttcta
     5221 attcatttac ttttgtttgg tattcttgga catctgcctt tgaatcttgc aatgtctgtt
     5281 ctttttgtgc tagtcgagcg gtaagatctg taatcgcttg ctctttatct gtcaatgtat
     5341 gatcaagctg tgtcagattc tcattgattg tatcaatatc tgtctctcca ccccacaaaa
     5401 taatttcatt tgcgtaccgc gtgcctgtgt agccaattag acatagaaat gcaacgacaa
     5461 tcccaccagt aataaatttc tttttcattt gcatagctcc ttaatccaat acttttacat
     5521 gctaaaagta agtgatctca aacacaatgt caagcgtttt taaattacat atgtaatttt
     5581 aatataaata ctatcaaata ctcatttaat cctccttttt tatctattta aaaaatcttt
     5641 tttatagaga aaaatgcagg ttaatacttt cttaaataaa tatttatggt gaacaaaaac
     5701 aaaaaagcaa gttttattaa acgtaaccct tttcatttca tagattactg tatttattac
     5761 aaaaaacg
//
LOCUS       DAIGWC010000112         5323 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.115, whole genome shotgun sequence.
ACCESSION   DAIGWC010000112 DAIGWC010000000
VERSION     DAIGWC010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.115"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..2008)
                     /locus_tag="NOB74_002625"
     CDS             complement(<1..2008)
                     /locus_tag="NOB74_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI1221758.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
     gene            complement(2024..3020)
                     /locus_tag="NOB74_002626"
                     /pseudo
     CDS             complement(2024..3020)
                     /locus_tag="NOB74_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            3218..4459
                     /gene="sstT"
                     /locus_tag="NOB74_002627"
     CDS             3218..4459
                     /gene="sstT"
                     /locus_tag="NOB74_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HCI1221759.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            4606..5241
                     /locus_tag="NOB74_002628"
     CDS             4606..5241
                     /locus_tag="NOB74_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCI1221760.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
BASE COUNT         1627 a          860 c         1015 g         1821 t
ORIGIN      
        1 ttttttgtgt cgcccatgtt gcactgtact ggttacctgc aacaagatca tattgtatca
       61 gacgataatc ttctagaatt tctttttgtt tctcagttaa atttttttct tggataattt
      121 gactatcctc tgtaacaaag acctgttttc cattaaaacg attagacaag ctttctgtag
      181 gatcaattgt taatgcaggt agatgattag atacttctgt caacaacgca tagtaaggag
      241 ttactttgat attcgcatgc tcaagagcca tagcaccaaa gttattagga gcaacaactt
      301 ctttatttaa cgtagctgct tgttcacgac tatacttgtt gttataaatg aaataatctg
      361 tctggtgctg ttctaatcca tattttttcg aatcattccc actatagatt gcgggtaaat
      421 ggtcaccata aaaaacaaag gtaatcggtt tatcgatttt gtcgatttct tggatgaatt
      481 tttttactgc tgtatcggta tagtgaaggc cttgcatata agtttgtaat tcttttcttc
      541 tattaggaat gacagcagtt ccttcagcag tgtagttcaa ttcactatag taatcatcat
      601 aaggcatatg gttttgcata gtggataatt ggatgaattg tgacgtttct gtattgcttt
      661 gtaaagcttt caaggtttct ttgtatgctg aatcatccga tatgcgtggg ctttgttcta
      721 ttttatccgt ataagttaat ttatccggac tgtctaaata atagaacctg tcaaaaccaa
      781 atttatcaaa cacttgtttt ctgcgataaa gagcagctgt aaaaggatgg atggctattt
      841 tttcatcgaa tagatcggta atatttggac ttattttctg acgctccact agctgggtat
      901 aaggtgtaac taacgaagca gacaggttac tgatactcaa gcctgtcagt ccttcccatt
      961 ccatgttagc tgttccgcca ccataaccga cggataacat caatcctcct gttccttctg
     1021 ttataatgct tttgatgtaa ggaatagggt ctgtaggtac tgtcagatta gggacacgtg
     1081 caggatcact gaagctttca cttaaattga gaacgatcgt ctgattgttt aaccagtcac
     1141 ttcttgtttg gttgatttca tctgcctttg tgttgtactt tttcattatt ccattaattt
     1201 tttctttcga atagccagca ggttcttcca tgattttaat gtcgatattg tttaggaatt
     1261 gaatgactgg tccgttatct tttacggcgc cttgctggtt aaagaaagtc ttgtttactt
     1321 taaataaatt aaacagcaag aaagaaggcg aatttttgtg attaatgaaa aagacacccg
     1381 aaaaacatcc taataataca gcgatactga taaatcgacg tttccaatga atcttcaagg
     1441 aatactgttt ttgtagtcta cgttgtacaa taatactagt aatcaataat aggagaagga
     1501 tcaatccgcc cacgattaat aagactgggc taaccatcga taatagttct gacaatccgg
     1561 tcagtatttt taaatctgaa ggaaagacag gctcttcccg catttccatt ttgattactg
     1621 tcgaaatagt gagcagtaag ttaatgatca aggtagcagt caaggcgtac caaaaacgat
     1681 tggaaatcaa caatagtaag aagaaaaatc ccataataat gatgattgtc aggatcatgg
     1741 gtgcttgtcg ctgagtaaat atttttaagg caacctggat agtttctttc caaccttctt
     1801 ttggttctaa aacgaaaatc tgcacgaagg taaagcagta aaaaaatgct gcaactaaaa
     1861 aataactttt atgaacaaaa agccaatgaa ttcttttttt ccaacgctga gttaattgtt
     1921 caatcgaatc aaaagcgaag tattcgatga aacgatgaat gaaacggatt ttttgtatat
     1981 aaaataaaaa gataactagg agggacactg ctaataaata gcaaataaaa aactgcccga
     2041 tatttatcag ccatgccttc cctgagtttg gaaattcacg tttcataaat gtagatacgc
     2101 gataagaaac taaagggaaa ttacatataa cttgagtgac aatcaaaaat acagcaagaa
     2161 aatttcctct tccttttata cctaatttat cagatagcat ttctaaaaat aaaaacgaag
     2221 agaaagtata atacattgcg aagagagaat atggtttaga aaacctcagc gctgtatctg
     2281 tatttcctct gatgatgagt gaaatttgtg tcatcaaaat aatcaaaccg aataaaacaa
     2341 tcaagctgat aaatacttga ggaagcttat agcggacctt ttctttccag ttccattctt
     2401 tcaaaccata acccattaaa aataaataaa aaatccataa aatactctgt ccattctgta
     2461 atgcaaacgg gtctttatta aatagagtag agcagccaac taatccaatt gttaaaaata
     2521 atagtagata tttaattgtt gttttcgata atttatttaa aaatccaact gtataaggaa
     2581 tactacaaaa aagcaaagta caagaaacag cataagtaaa gtaattctga ctgataggtg
     2641 ttaggataag ccaataatca cgaatattca agctgccagc ttgtacgtaa aaaaaagata
     2701 ttgcaaacta gtgtggctat taggaatata aaggcaaaac gacttaaata atgtaaaact
     2761 tttaaacggg cgattttttg atattggtaa cccatgtaaa gtgggatcaa atttgcacca
     2821 ataacaacgg aagtttgtaa aaatgtatag atgtagaatc gaccagggtt tgttgcatat
     2881 gtaggaatag tgactgctga aatcaatata cgctgtaaaa ccatcattat acaagcgaca
     2941 aagattgtca ggaagccata actctccttc tttatttttt tcaagaataa acacctcaca
     3001 aaaaaattgg acaaaaacat aagaaaacgt ttcctgataa gttgcccatt aataacatcc
     3061 taacttagaa tatctcaaaa aacaacgtgt agacagaaaa agtacaaaat tagcaagaaa
     3121 tggttgtttg tattgttaga atttttagaa aattatacct ttagtttctt tgcataaaat
     3181 gatacaatga ttgttaaaat tgtgaaaggg tggtcatttg ttagagaagt ttttggatat
     3241 gtcgttagtt caacgtattg ttgttggtat tttagtcgga atattgtttg gtatcttttt
     3301 ccccacatgg acatttattt caatattggg aacgttgttt gtcagttgct tgaaggcaat
     3361 cgcacctatt ctggtttttt tcttgacgat ggcgtcaatt gccaagcata aaattgggaa
     3421 taagacattc gtgaagccta ttttgatctt atatttagtg ggaacattgc tttctgcact
     3481 tgtagcagtt attgtaagtt caatttttac tgttcctatt actttacaag aaacagtatc
     3541 tgaaaaagca ccgcaaagtt tggaaagtgt tttatctact atgttgacga atgtcacaca
     3601 aaatcctgtt caatctctta ttgatgcgaa ttaccttggc gtcttattct gggctgtatt
     3661 gttgggacta gcttttcgag cacgttcaga atcgacaaaa gagttggtgg atcagatatc
     3721 tatagcgttg tcacaagtcg tacaagtgat tattgcattt gctccgatag ggattttagg
     3781 attggtttat caatcaattg ctacgactgg aatagctgga ttggcagagt atctgcagct
     3841 tttacttgtt ttgatcggta cgatgctgtt tgtcgcatta gttgtgtacc cattcctcac
     3901 gtttttgttt attaaagaaa atccctatcc attgattttc ttttgtttga aagaaagcgc
     3961 acttcccgct ttctttaccc gaagttctgc cgcaaatatc ccgataaaca tgatgttggc
     4021 tgaaagattg aaattgacaa aagagtctta ttccatatcg atcccgttag gtgctacgat
     4081 caatatgggc ggtgccgcga ttaccatttc cttgatgacg ttgactgctg tacattcttt
     4141 agggattgaa gcaccttttg ttttgaaagt ccttttatgt attttgtctg ctttagctgc
     4201 ttgtggagct tcaggtgttg cgggcggttc actgttattg attccattag catgtagttt
     4261 gtttggtatc tctaatgatg tcgcgatgca aatcgtcggt attggattta ttatcggtgt
     4321 tatccaggat tcaatggaaa ctgccttaaa ttcgtcaagt gatctgttgt ttactgcaat
     4381 aggagagcta ggcgcgcgta aaagaagtgg ggaaaaaatc aaattgaaag attgtttaga
     4441 tggattaagt gaacgttgaa cgttagatat ttagtatttt taaaatgatt cgagttttta
     4501 atgagttata tagatgttcg tgtaaataga ggtttctgtt aaatcaagat aaagtcgctt
     4561 ataataacaa ttaaaagcat aggtaattgt tattggaggc gtatcatgga ttttttacgt
     4621 aaatttggtt ttttcttttt attattaggc gtgctgagtg attttttgac tccgtacgta
     4681 ttaggattgt attatcctga attagatcaa atgaagagcg tgatcagtgt atttggagag
     4741 gtttccagtc ctgtaagaaa agcgtttctt atttggtctg tggtttcagg gatctttttc
     4801 atcctgtcat tgcctgcatt gtatgctgca tttgtaagta catctcgtgt gttagctacc
     4861 ctagttacag cagccatcgc gttctatggt ataggtgatt gtatctttac aggtttgttc
     4921 agtatcaata cccatgaatc ttcgtggaat gtctcgacat gggtccataa tatcggatca
     4981 ggtttaggtt acagtggttt tttattgttt ccagttcttc ttttcttgat ctatcgaaaa
     5041 aatgggcaaa tggacgtaag ccacttatac cttggactgt ctgtgatcag tttgcttttt
     5101 gcggcgattt atggactggc aagaattcct tctataaatt cttggccatt actgaataaa
     5161 ataggttttt gccaaagaat cagttttttc tttaattatg tgcccattgc ctggttgagt
     5221 atcttgcatc tcaaacagta aaacttgagc cgtcaaattg aacagtcagc ggatacttca
     5281 tccggtggct gttttttgtt tttctgaaat atatatttcc aca
//
LOCUS       DAIGWC010000113         5311 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.116, whole genome shotgun sequence.
ACCESSION   DAIGWC010000113 DAIGWC010000000
VERSION     DAIGWC010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.116"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="NOB74_002629"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="NOB74_002629"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HCI1221761.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="NOB74_002630"
     CDS             complement(1297..2133)
                     /locus_tag="NOB74_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1221762.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="NOB74_002631"
     CDS             complement(2317..3534)
                     /locus_tag="NOB74_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI1221763.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3862)
                     /locus_tag="NOB74_002632"
     CDS             complement(3683..3862)
                     /locus_tag="NOB74_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221764.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3917..4000
                     /locus_tag="NOB74_002633"
     tRNA            3917..4000
                     /locus_tag="NOB74_002633"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..4818)
                     /locus_tag="NOB74_002634"
     CDS             complement(4240..4818)
                     /locus_tag="NOB74_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221765.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(4824..5207)
                     /locus_tag="NOB74_002635"
                     /pseudo
     CDS             complement(4824..5207)
                     /locus_tag="NOB74_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1081 c          838 g         1739 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagttaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca t
//
LOCUS       DAIGWC010000114         5306 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.117, whole genome shotgun sequence.
ACCESSION   DAIGWC010000114 DAIGWC010000000
VERSION     DAIGWC010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.117"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(56..1195)
                     /locus_tag="NOB74_002636"
     CDS             complement(56..1195)
                     /locus_tag="NOB74_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI1221766.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(1504..2217)
                     /locus_tag="NOB74_002637"
     CDS             complement(1504..2217)
                     /locus_tag="NOB74_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HCI1221767.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(2471..3172)
                     /gene="nagB"
                     /locus_tag="NOB74_002638"
     CDS             complement(2471..3172)
                     /gene="nagB"
                     /locus_tag="NOB74_002638"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HCI1221768.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            3406..4938
                     /locus_tag="NOB74_002639"
     CDS             3406..4938
                     /locus_tag="NOB74_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI1221769.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(5129..>5306)
                     /locus_tag="NOB74_002640"
     CDS             complement(5129..>5306)
                     /locus_tag="NOB74_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1221770.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         1744 a         1080 c          892 g         1590 t
ORIGIN      
        1 taaaaagagt ttagcgtaca gatattttaa atgtacactg aactcttttt tatgcttatt
       61 cacttgtttc ttccagcact tttggactgt ctaacttttc cgaaacatgt tccattcttc
      121 tcaataaata gattttccgg atatttaata ttatcgtctt aatcactgca tagacaggta
      181 tgcaaatcag catgcctaat attcctgcga cacttcctgc tccaatcaat accaagatga
      241 tcgtcaaagg atggatattc attgatttcc caaataacaa cggcttgatc aaatttccat
      301 ctaattgttg gatcactaaa atcgacaacg ccatatacaa agcttgaaat ggagagataa
      361 acaaaccgac aatgattgct ggtaccgctc caataaaagg gccgacatac gggataatat
      421 tcgtgattcc gcaaatgacc gcaagcaaca agctataagg ctgatcgaat attctcattg
      481 ccaaaaagct cattacacca ataatcaaag catctaagat cgtactgctg atataggcag
      541 ataatgtttc gtttaattct tttaccgttt ggcgtaactc tttacgaatc gctttcggaa
      601 agaagtgaga caacgcatca ataaatttgt gcccatcctt gaacataaat agcaaaataa
      661 atggaacggt aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt tttgagacac
      721 ttgcagataa actgactaat atgatattga acaaattact aagagataaa tttgctgatg
      781 ctaattgttc ttccaaattg aaatttttaa actcttcccg ctgcgccaat tcatttaacc
      841 atttgcttgt ttcatctgca tacattggca agctctgggt caattgaatt gtctgttcca
      901 ttaactgagg cactacattc atgacagtta aaacaactaa aatgattacg accaaaaacg
      961 tcaataaaaa accgaacact ctcgggatcc gatgcttttc gagaaaaaca acgattggat
     1021 cgaacatata atagataaaa ccagcaacaa gcaatggtaa aaaaattgcc gaaagcattt
     1081 tcaatattgg actaaaaata ttcggcattt gtaaaataaa gtacacgccg atgatcgtga
     1141 gtactagctc cactgtccag aaaaataatt ttgattgttt aaaacgtgat tgcatacatc
     1201 tcctccaagg tcctttgata cttctattct atcatttaac aaagagttac gcgctgagat
     1261 tttcatttgc ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag acgagtactt
     1321 aaacaaaaac acggtttgga gtagtgacaa aaattatact gcagtccctt tttccaaata
     1381 aacggtgttc aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa atataaggaa
     1441 ctatttttat ttggctgggc ttattacttg atgtaggaca tctattttac aacctcagat
     1501 catttattgc gcaatactga ctaaatgcaa ctttgtgata tttttgtgta cggacaactc
     1561 ctcgatcaca tcggcataag tgagcccttt tggaagatca atcgtataga tatttttgta
     1621 cactcggtag tcatcaacga attttacgtc aaaattcaca tcttcgatta cgatattttt
     1681 ctcttcaaaa taatcggtaa gaaaatcttt ggtttctttt ctatggataa attggatttc
     1741 taacttttta gtcgtaggta catggatcac gcgtttcact actgtgagtg caatagcaat
     1801 cccgataaaa ctgatgatcg caatggaata gtaacccatg ccgatggcga tccctaatcc
     1861 agcaattgcc cataaagaag cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat
     1921 gatcgttccc gcgcctaaga aaccgacacc actcaccact tgagcaatca gccttgcttc
     1981 atctgaacga atcgttccag caagctgtgg atactctaaa gcatctctta atgcaccact
     2041 agcgatctca acttggatca atgcaatgat acatgctccc atacaaacta aaatatgcgt
     2101 acgcatacct gctggacgat ttttatattg tcgttcaaaa ccgattgctc cgccaaatag
     2161 catagcgatc cctaaacgta aaataatctc tggaattgtc aataccatat cattcatcta
     2221 aacaccctcc agtccaatat atcatgtctg aaaggagcag acaaaaaaag tgcaattttt
     2281 acctcttacg aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt atgaataaac
     2341 ggtgttcaat cagctgaccc tcggtattac tcaacaaacg gcaaaatatg gggagctatt
     2401 tttcctttgt cttctctaat actcaggtca aaacgctgat ttcacaacct ctttagccta
     2461 ctattgaaaa ttacaactta cttgctgctt cttcatcgat gatcacaaca acattgtcgt
     2521 gattttgcaa tacacttgct ggcaaatgat tcgttacagg tccttcaatc atccctttga
     2581 ttgcatcagc tttgctttcg ccaaatgcca tcaagacgat ttctttactt ttcataattg
     2641 aaccgattcc cattgaaaca gcttttgttg gtacatcttc tgctttatcg aagaatcgtt
     2701 tgtttgcatt gattgttgat tctgttaagt caactactga agtcgttccg tcaaatgaag
     2761 caccaggttc attgaaaccg atatgtccat tttgcccgat tcctaagatt tggatatcga
     2821 ttggatgtgc atcgatgatt tgatcatact ttttgcatgc tgcttccaga tcttctgctt
     2881 ttccatctgg tacaaacgtt tctttgaatg gttttttatc aaataattgg acatccatga
     2941 aatgacggta gctttgttca tctgaaccgc ctagtccaac gtactcatct aagtttacag
     3001 aagtcatttc actgaaatcc aaatcgcttg aagtcatttc tttatataaa gtaactggtg
     3061 tgcttcctgt tgccaatcct aatacttttg cacctttgtt cataccttct ttgatgattt
     3121 caaatgcttt ttttccgcct tcttcagcgt tttttacacg aatgatttcc atagtgattg
     3181 ctcctttata ttttggtata gcccaattat agcattcttt ttttcttttt acaataatta
     3241 gtatagacca aattgcattt ttttcatttt cttgacaata aataggaatc cgtgttaggt
     3301 ttcataagat ggttcaatca aacaatccat gttgcatgaa aaccaagcaa gtgattcact
     3361 gtggacgctt tatgtctgca gtttttttat gaaaaaggag ttattatgag tatactgaca
     3421 ttaaacaaca ttacccagca atttggcgac aaaatcctct atgaaggtgt cgatctgcaa
     3481 ttaaatgctg gcgaacatct tgggctgatt ggacaaaacg gagccggtaa aagtacattg
     3541 attaaaatca tcactggtga gatcttacca gatgacggac agatccattg gcaaaaaaat
     3601 attcacaaag gttacctcga tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa
     3661 tttctaaaaa ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc ttttctttac
     3721 caaacatata gcgagacctt cgatgattcc ttgctggaaa aagctgggaa actccaaacg
     3781 gaattagacc aaggagtgtt ttatcaaatc gacaccttag ttgctgagat gagcagcggg
     3841 ttggggatcg atgtcttagg tttagattca ctgttgaaaa atctaagtgg tggacaacgt
     3901 tcaaaggtga ttttagcaaa actactttta gaaaacccag atgttctgat cttagatgaa
     3961 ccaaccaatc acttagatga tcagcatatc caatggctga cgcagtttct tcaggatttt
     4021 gacggtgcgt atatcgtgat ttcccatgac caagaatttc ttgatcagat caccacccat
     4081 atcgcagaca tcgagtttgg aaagattact aagtatactg gccatctaaa acaagcattg
     4141 aaacaaaagg aacaaaatcg cgaaagctat ttgcgccaat atcatgctca acaaaaacaa
     4201 atcgaaaaga ccgaagctta tattcgaaaa tacaaagccg gttcccgatc aacgatggca
     4261 aaaagccgac aaaaacaatt agataaaatc gaacggctga cgcctccagc ttcagcaagt
     4321 aaagctgtct ttgattttcc attctcgcct attgtcacga cattagcagt ggaaacaact
     4381 gatttagtca tcggatatga tcgaccgcta cttgcaccca tcaatttgac catccgcttt
     4441 ggtgaaaata ttgccattcg aggcttcaac gggattggaa aatctacttt attaaaaaca
     4501 ctgatcggtg agattgaaaa aataagtggc gatttccact tcccagataa cacaaaaatc
     4561 aattactttt cacaagatct gtactgggaa aatccattag aaacaccact acaatattta
     4621 agcagtcaat ttccaaaagc gactatcaaa gaattacgtc gccaactagc taaagcaggg
     4681 ttagttaatc aattagcaag tgaacctctc actacattaa gtggtgggga acaaactaag
     4741 gtgaaacttg cacagttgac aatgaaccaa ggtaatttac tgattctcga tgaaccgacg
     4801 aaccatatcg atcaagaaac gaaagaaagc ttacaagacg ggatacagaa atttccagga
     4861 acagtaatca tcgtctctca tgaacaagaa ttttatcaag atcttgtgca acgagtcatt
     4921 gagattgaac caaaataaac gtttgattga atagttgaaa aaaaggagct gtgacaaaag
     4981 ttttgtcaca actccttctt ctgaataaat ggtggccaat tagctgacct tcggtattag
     5041 ctcaaaaaac ggcaaaatat gaggagctat ttttatttgg ctattcttat tacttgatgc
     5101 agaacagctt ttcacaacct cttttcgtct attttttatt ttcgagattt ctctttcctt
     5161 taaaaacaac tgtttgaaag aagaacgcac atccttgaaa aacaagcccg ctaaccgtta
     5221 cacctaacca gccatactgc tgccacattg tcgtccctag caatgaacca gccgcacctc
     5281 caataaagta cataaacata aataca
//
LOCUS       DAIGWC010000115         5302 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.118, whole genome shotgun sequence.
ACCESSION   DAIGWC010000115 DAIGWC010000000
VERSION     DAIGWC010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.118"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(449..952)
                     /locus_tag="NOB74_002641"
     CDS             complement(449..952)
                     /locus_tag="NOB74_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI1221771.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1075..1839)
                     /locus_tag="NOB74_002642"
     CDS             complement(1075..1839)
                     /locus_tag="NOB74_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HCI1221772.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            1947..2222
                     /locus_tag="NOB74_002643"
     CDS             1947..2222
                     /locus_tag="NOB74_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HCI1221773.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            complement(2423..2770)
                     /locus_tag="NOB74_002644"
     CDS             complement(2423..2770)
                     /locus_tag="NOB74_002644"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221774.1"
                     /translation="MIPSVSFLFKKLKTFFILPEIEESNELTASDRSAFLLPVFNTWG
                     KAPQKQPYRRCSKVSFLVLRQIYAKMWKAIFTKFSLILKTKRLFHNQSLMLDADQLFH
                     NLIDGVLSAASRY"
     gene            2938..3867
                     /gene="yidC"
                     /locus_tag="NOB74_002645"
     CDS             2938..3867
                     /gene="yidC"
                     /locus_tag="NOB74_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCI1221775.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQPKNSTNNKGRNAGKQQKRK"
     gene            3970..5302
                     /locus_tag="NOB74_002646"
                     /pseudo
     CDS             3970..5302
                     /locus_tag="NOB74_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT         1684 a         1006 c          983 g         1629 t
ORIGIN      
        1 attataaaaa aatattggta tggttttatt gtttgttcca tgattttaaa gtcctttctt
       61 ctaaccaaag tgcatacttt gtagaaaaaa gtgatcttct gcaaagtatg tgttacctga
      121 agatcctgga ctcttttaaa taagatacgt tttgcatctt atcatcaccc cctttaatgc
      181 ttattattct atgtacatga ttcattcgat aaataaaagt aaaccgtatc ttgaacagat
      241 agtcaactgc aaacagaaaa aaggactgtg acaaaagtcg tgtcaaagtc ccttgtttcg
      301 aatgaatggt gttcaaaagc ttgcatctgc agtaataagc cgaaacttca caaaaatttg
      361 agaagtaatt ttcgtaaatt ccttcttatt tcttgaagct gaccacttct gtcacaacct
      421 caatatggtc tattattggt tttacctgtt aaatcgagga ttctttccca aagtaacgtt
      481 gccatctctt acgcatactt gcagacatgg gctgagccgc ttctttgact gcgcagtatt
      541 tgtccacgaa tgtcacaata tatccttctt tatacttagg cggtgcgatc gttgcacccc
      601 acatgtgctt caaaatgata tctcgctcaa gatccgacaa atcggtgatt ttttctgcat
      661 tctttacagc aattcttgga tggatatacg catgtgtccc ctcgtcaaat ttcgtcgtac
      721 gccaatcata gtagaacaga tcatgcaaaa gtccagcacg cgctgttgct ttagcattgc
      781 caccccattt ttttgcgagc agataactat agtaagaaac actgatggaa tgctccaaac
      841 gagtggaatg aacatgctgt gtgtaattcg ctaatttttt cactgcttct gtttctaaaa
      901 gatcttgtac ataagacata tattcttcgt cttcacgcca tttttctgtc ataattatcg
      961 atctgccacc tttttgaatt tcattttctt ctgaaattga tctaagtata ccaccagtgt
     1021 tcggattatt ctagtcgctc tagataaaat agctaaagct taatagttcc ttaatcataa
     1081 agaaaaatga taaagaacga tccctgctgc gactccgaca ttcaatgatt ccgcatttcc
     1141 tttcattggg atatatacgt tctgatcagt caaagacaag atttcctgac tgactccctg
     1201 accttcgttt cccatgatta tagcgaaatc ctctgttttt tctactttgt ctaatgcatg
     1261 tgcttcttca tttaattctg taccgtacac cgtaaaccct ttgcctttca ttacagggat
     1321 tacatctgcc aaatcttttt gtaacacagg caaatgataa ttgcttccct gcatgcttcg
     1381 cagcaccttt gtactataaa tatctgccgt tcctttacct aataaaacac cagccatacc
     1441 aaacgcatct gccgtacgga tcatcgttcc cacatttcca ggatcctgta cattatctag
     1501 taaaagccag cctcctgaaa aatctggcgt atcttcagat gttaacgtca tcactgctaa
     1561 gatcccttgc ggtgtaggta gatctgacat agcggtcatg acctcatctg aaactagaaa
     1621 agtagaaatc tctttgttta cagccagcca gtctccccat tctttcatac ctctctgtgt
     1681 cacaaaaagt tcttttattt ctgcatcaga cgacgcagct tcttcgatca gatggaaccc
     1741 ttccaaaaga tattctgcct tttcttctct gtatttcttt ttatgtagtt tttttaattc
     1801 tttgattctt ggattttttg ctgattggat ctctttcaca ttccttcacc tcacctgatt
     1861 atatcatgga ataggtgctt gagcttgttt catcctaaaa aaatcggtat cattgattta
     1921 taaaacagga aagaaaggtg acgaacatgc gcaaagttaa aatgaatgtc caaggacgtg
     1981 tccagggcgt gggatttcgc tatatgacca agatggttgc tgatcagtta ggcgtgaccg
     2041 gaacggtaaa aaacgaagac gacggctcag tcacaatcga agcaatcgga aatgacgaca
     2101 tcatccaaaa atttatcgaa gaagtcaaga agtctccgag cccaagtgga cgagtgcagt
     2161 atgtggatgt ccaagaagat ccgatgattg aggaacgaaa gaaatttgat gtggtgggat
     2221 aaggttgtga aaaggtcgct tagttttgag tattaaggaa aattttgtga aaatggcttt
     2281 ccacattttt gcataaattt gacttaatac cgagaaactg acttttgaac accgtcgata
     2341 aggttgtttt tgaagcgctt tgcctcgagt attaaggaga aacattttca aaatagcttc
     2401 tcatattttg aaatgtaatg acttaatacc gagaggcagc tgataaaaca ccgtcaataa
     2461 ggttgtgaaa aagctggtct gcatcaagca ttaaggactg gttgtgaaaa agtcgcttag
     2521 ttttgagtat taaggaaaat tttgtgaaaa tggctttcca catttttgca taaatttgtc
     2581 ttaataccaa gaaactgact tttgaacacc gtcgataagg ttgtttttga ggcgctttgc
     2641 cccaagtatt aaagacaggt agtaaaaaag ctgatctatc acttgcagtg agttcatttg
     2701 actcctctat ttcgggcaga ataaaaaaag tttttagttt tttaaataag aaagaaacac
     2761 ttggaatcac tcttttcttt ccaagtattt ctttcttgat tttttgtctt ttttcaaaat
     2821 ttttcgctac gaaaaagaaa gaatatttat atgaaatttc tatgaagttg attgaattcc
     2881 atgcgctttt ttagtatagt taagtttgtg taaaaattat agaagaggaa gtattctatg
     2941 aataaatgga aaaactggtt attgggatcc ggacttgtca gtatcctgct ctttttatct
     3001 ggctgtgtgc ggatggattc aaacggaaac cctgacactt caggaatcgt ttatcgagta
     3061 ctcgtccatc ctatgggcca agcgattaca tatctagttg agaatttcaa ttggtcttac
     3121 ggctgggcag ttattgcaat gactgtgatc gtccgtatca tcatcttgcc actaggtatc
     3181 agtcaatcaa aaaaaacaat gatccaatct gaaaaaatgc aagcgttaaa accacaagtt
     3241 gaagcagcac aacaaaaact aaaagctgca acaacacgtg aagaacaaat ggcagcacaa
     3301 gcagaaatgc aacaagtata tcgcgaaaac ggattgagta tgaccggcgg aatcggctgt
     3361 ctgcctctat tgatccaaat gccgatcttc tctgccttgt attttacggc tcgctacaca
     3421 gaaggtatcc gtgaatcatc tttttacggc atcgatctag gctcaccaag tatggtgctt
     3481 gttgccattg caggggtcgc ttatctgctt caaggatata tttcaacaat cggtattcct
     3541 gaagaacaga aaaagacgat gcgtacgatg ctgatcgtct ctcctgctat gatcgttttc
     3601 atgtcgatca gtgcgccagc cggtgttaca ctttactggg tagtgggtgg tgtgttcagt
     3661 tgtctgcaaa cattcatcac aaacgttatg atgaaaccac gtttgaaagc acaagtggca
     3721 gaagagttga aacaaaatcc gccaaaacaa gtcgtcactc caagaaaaga cgtgacagaa
     3781 tcggcaaagc cagctgacaa taaacaacca aaaaacagta caaacaacaa aggccgcaac
     3841 gcaggaaagc agcaaaagcg gaaataaaaa tatatgacaa aaaactgtag acaaataaaa
     3901 aaatttcttt gttctacagt ttttttgtta caatcaaaga aaacgtcgct tttcgaggag
     3961 gaatgtataa tgatgtccaa ataatcaatg gatagtcgaa tggaagaagc caaaatttcg
     4021 ctagatgcac ttgttcctaa aaatcatttg gtccataaaa ttgacaaaat attgttattt
     4081 gattttattt atccaattgt tgaatcaact tactcgacca ttggtcgtcc tagcgttgat
     4141 cctgtcatct tagtaaaatt agtattcatt caatatttat ttaggattcg ttcgatgcgt
     4201 cagtccatta aagaagctga aacaaaccta gcttatcgtt ggtttcttgg gcttagttta
     4261 atcgataaaa ttcctcattt ttcaacgttt ggtaaaaact atgtacggca tttcagagaa
     4321 accgattgtt tgaacagata tttatcatta tccttgaaca agcagttgaa gctagattta
     4381 ttcatgaaga aattttgtat atggattcaa cctatattaa agcgaatgcg aaaaaacata
     4441 tttttacaag agaaatggta cataaataag ccattttata ccaaaaacaa ttgaaagaaa
     4501 aaattaatga agcaagaatt gcagaaggca aacgtccttt tggttcaatc attcatcagg
     4561 aggtggtaga agggaaaatt agtgtcgcag atccagaaag tggttattat gtaaaaacag
     4621 aacaagaaaa acagtttgct tattctgctc ataccgtttg tgatgaaaat ggttttgtat
     4681 tagatgtcat gattacgcct ggaaatctac atgacagccg aatgctcgtg ccacaaatcg
     4741 aacgtgttaa atcatgttgt ggtgtagctg ctgatgctgc gtacaaaaca ccttggaacg
     4801 ccaagtattt aatcgatcga aaactacgac ccatttttcc ttatactcga cccaaaagaa
     4861 gcaaagaacg ttttaaaaag aaagattttt attatgatcc ctattataac tggtacctat
     4921 gcccaaatga tcaaacactt cagtttcgca caactactcg agatggttat aaaaaatatg
     4981 tatctaaatc ttttatttgt gaaagttgtc tattattgaa aaattataca gaaagccaga
     5041 aacaccagaa agaaatacat cgacatattt aggaagacta cttagatgaa gcagaacatt
     5101 tacgccatac ggtgtacaat cgcgaaaaat ataaaaaaaa gaaaagaaac gattgaacgc
     5161 gtttttacag acgcaaagga aaagcatgga atgcgctaca ccaaatatcg aggcttggaa
     5221 aaaaccaggt gcatacgatg cttgtttttg ccgcaatgaa tctgcaaaaa ttagccattt
     5281 ggcagtgggg gcatatgtct tt
//
LOCUS       DAIGWC010000116         5206 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.119, whole genome shotgun sequence.
ACCESSION   DAIGWC010000116 DAIGWC010000000
VERSION     DAIGWC010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.119"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            33..1367
                     /locus_tag="NOB74_002647"
     CDS             33..1367
                     /locus_tag="NOB74_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221776.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1354..2988
                     /locus_tag="NOB74_002648"
     CDS             1354..2988
                     /locus_tag="NOB74_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221777.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3163..3996
                     /gene="msrA"
                     /locus_tag="NOB74_002649"
     CDS             3163..3996
                     /gene="msrA"
                     /locus_tag="NOB74_002649"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI1221778.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4109..5065
                     /locus_tag="NOB74_002650"
     CDS             4109..5065
                     /locus_tag="NOB74_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI1221779.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1824 a          806 c          951 g         1625 t
ORIGIN      
        1 gtttttatta tggagaaaag ttttttaaaa agatagatgc tgctttttta tttagttgtt
       61 tatatacttt tgcaacttat cgaacagttg atatctatta tcgatccgca attgcagaag
      121 caatcgctct tacgattatc ccagctgttt tatattatgc ttatggattg atattcaata
      181 gagaaaaaaa agtcatcgct ttatctgtca gtataagtct acttgtgtat actcatgtct
      241 taactacact attgtgtagt gcattgattg cttgtatgat tatagttcgt ttgtttttaa
      301 gcaagcaaat aaaaaacgat ataaaatttg tggtcgtgaa tttagtaaag gctgtttttt
      361 tgacttgtgc attaactagc tatttttggt atcctatgtt gcagcagatg aattatcaag
      421 aaatacacag tcccttcaaa acagatttgc agctagaagc actttctatt tcagatagta
      481 tcattcaagc gttaaataac gatattacaa catacactat ggggttatta ggattggttg
      541 cgttgatttt tcctttattc atactgaaag aaatggagaa aaaagaaaaa atcatctatg
      601 ttggcgtagt ttctacatgg gtatgcgtaa ctaatttatt tccatggttt ttgtttcaaa
      661 aaacaccgat aagcttgctc cagtttcctt ggcgtatctt aggtatccaa atcttttttt
      721 cttcaatgat cataacgctt gtttttatga aaaagactat gaataaaaaa tattcatggt
      781 taatcattgg cgctactgtg gtgtttctac tcgtcacgtc tatagcagca aaagaaaatt
      841 acgcaaaagt tatccaatca aaacacggtc atattgttat caatgaagaa acactcccac
      901 gttatacaac atcagatatg ggaggattat acgattacgc cccaacagaa gcgataaaag
      961 aaaggcctca cttagaaaaa catgaagtaa aagtaggaga atcgtgggaa aaagggaagt
     1021 ataaagctgc agataataac attacttaca cagtggcaag caacaaaaag caaaaagtga
     1081 cagtaccagt atatgcttat ttaggtacac aggtaaaagt aaacggtaaa gtcgtaaatg
     1141 actcttataa aaaacatggc ttagtgaatg tggatgtaaa tgctggagaa aataagatag
     1201 aaattacaac aaaatatact ccaactgctc tcatggcttt atggatcagt attctgactt
     1261 attgtttagt ggtgtattca agttttaaac gatttgcacc taataagttg aaagattctc
     1321 gatatgtgac taaaaaggag ataaacaaga agaatgaaaa taaataaaaa agtagtaata
     1381 ttgagtggat taattatagt tagtagtata tattctttca tctttttcaa aaatacacag
     1441 agtatttata ccactggaga tctttctttt cacttatctc gaatcaaggg gttatcgact
     1501 atttttacca gtccgattaa ttatgagaca ttcaattata ctggatatgg tgtaaattat
     1561 ttttatccct ttctgacttt ttttccagct gtaatgttat attggatgac aaaaaatttg
     1621 attgtaagct atattattta cgtttggtta ttgaacttgt gtacaacact cgtagcttat
     1681 cattatggcg agcggttttt aaaacaaaaa aaagcggcat ttttatttag ttgtctctat
     1741 attttctctg cttatcggac agtagacatc tactatcgtt ccgcaattgc cgaagctatc
     1801 gcaataacac ttgttatccc tgtattattt tatgcttatc aaatcatctc tggaaaagaa
     1861 gaaaagtatc cgtctgtaaa gctagcattg agtatgagtt tgctagtgta cagccatgta
     1921 ctatcaacat taatgagtac agcattaatt atcattttta tttttattcg tttggtttct
     1981 aaaggtttca agaatgcaga ttttattgct atatttaaaa aattatttag tgcggcagga
     2041 atgacattgg ttctgacgag tgctttttgg tatccgatgt ttgaacaaat gctctaccaa
     2101 aaaatcaaca aacctagcgt gacaaattta tatgctcatg catctaatgt gttcgatagt
     2161 ctgactgaag ctatgaacaa cgacttaact acttactcaa tgggactagt tggtctgtta
     2221 tctttatgta ttcccctgat tttatttaaa aaattaacaa acatagaaaa aaagatttat
     2281 tatggtacgt gtttgacttg gctagctaca actagtttgg tgccatggta tcttctgcaa
     2341 aatacgccag ccaaattgtt acaatttcct tggcggatct taagcttgca aataatattc
     2401 tcttctctga tattaacgat gatatttttc aaaaatagaa gatacaataa gacaagagaa
     2461 ctattttatt tatttatgac tgttttgtta ttaatcactt taactgtttc tagtaaaaaa
     2521 aatttcaatc aaaaaataat ttctcagccg ggacatattg ttgtaaacaa agaaacagta
     2581 gaggcgtata ccactaaagg aatggattat tttttatatg attattctcc tatcgcttca
     2641 ttggagaata aggagcatat aataaaacac gaagcaaaga ttggcagtca atgggtaaac
     2701 cttccttata aaacaactgg tagttctatc atatatagag taactaatga gaagagccaa
     2761 gtaatcacac ttcctgtata tgcttattta ggaacgaatg tagaaataaa tcatcaacct
     2821 gtaaaggagc aggtgaatgc taatggattg gtacaaataa gcggagtcaa aggagttgct
     2881 gatattaaag taagcacaag ttatacagta acgactatta tttcttatct tgttacatta
     2941 actgcatatt tatgtttatt ttttaaaata gttttccata aaaggtaaat taacttttca
     3001 tttataaaat aaattgatta aaaaggagaa tctgtcgata aggattctct cttttttata
     3061 cgaaaaatct gtagggggat gaagtaatcg cttatttcct cactttatga taaattacag
     3121 ctaaagtcac tagcttgtct tcttcggaaa ggaggagaat ctatggatga ggaacaaata
     3181 ttcattcaaa cactttataa tctgattttg aatccgaata cacgagattg ggaacgaaaa
     3241 gtattgattc agacaaagaa tgacataaga gaaaatatat ccgttaaaga acagttatca
     3301 aaactagaag caacactacg tccattagct atccgaatga atctgacgcc tgatgtaatg
     3361 gacttttatt tattgattac ggaaggattt gataaggagc aaaaatatga cttttccaag
     3421 catgccatgc aagatgctga ctatcaagaa cgtgcagtat ttgcaggggg atgtttctgg
     3481 tgtatggtcg agccgtttga atcgaaaaaa gggatcctat ctgttttgtc aggatacacg
     3541 ggcggacatg ttgaaaaacc aaattatgat caagtaagtg gtggttacac aggtcatgtg
     3601 gaagctgtgg agatcattta tgacacaaga gaaataagtt atagcgagtt gctgacaatc
     3661 tattggcaaa ttactgatcc cacagataca tttggacaat ttcaagatag agggaagcaa
     3721 tatcgtccag tgatttttta tcaaggcgaa cgacaaaaag aattagcgga acaatcaaaa
     3781 cagaaactag acagttcagg aactttccac caaccaatcg tcacaaaaat cgaaccagcc
     3841 ggtacgtttt ggccagcaga aaactatcat cagcaatttt acaaaaaaca accgaaacgt
     3901 tataaaaaaa tccagcaagc acgtaatcaa tttctgatct atcaacgagt aaaaaacaaa
     3961 tggcaaaaaa atatacgaaa aaatcatttt gattaactcc ttttctttaa aatgtagtaa
     4021 actaaaaata gaaaaaagaa agcgttttaa aaagatttga tgaggaggag aaaaattgta
     4081 tattgcagat agtgcacgtt atgaaaaaat ggaatatcgt aaatccggtc attcaggttt
     4141 gaaattaccg attttatctc tcggattatg gcaaaatttt ggtgattatg atcctatcca
     4201 taatcaaaga gagattttaa gaggcgcatt cgacatggga attacccatt tcgaccttgc
     4261 gaataattat ggaggccctg ctggagctgc agagaaaaac tttgggcgta tttttagaga
     4321 agattttcaa gcctaccgtg atgaactgat tatttctagc aaagcaggtt atcatatgtg
     4381 ggaagggcca tatggggaat ggggctctcg taaatccatc atttcaagtt gtgaccaaag
     4441 tctccaaaga atggggctag attatgttga catcttctat catcatcgcc cagaccctga
     4501 tacacctttg gaagaaacag cagaagcttt gatgcaactt gtaagacaag gaaaagcatt
     4561 atatattggt atatccaact ataatggaga agatacaaaa aaaatgactg aaattttaaa
     4621 aagaaaggaa gcaccgttca ttattcatca gatgcgctac aatatgtttt ctcgtgcact
     4681 actagaagac gatctatctc cagtattaga agaagaaggg ctaggggcaa tcacgttcag
     4741 tccgcttgct caagggttgc tgacaaatcg ttatctacat ggtattcctg aagattctag
     4801 agcacatcgt aaggaaatac cattcctttc agaagaacaa gttggatcaa ctctggaaaa
     4861 aatcaaagca ctgcaaacaa tcgccgtatc acgaggacaa tcattagcgc aaatggccct
     4921 tgcatggaat ttgcgacaaa aatctgttac aagtgtactg gtcggagcaa gtcggttaag
     4981 tcagttacaa gaaagtgttc gaatgatgga taatttagat ttctcaccag aagaagaatt
     5041 gagaatcgac caaattctag aatagaaacg atgtaatcaa actttttatc catatattaa
     5101 aaaaaacaaa agatgacatc aagaatcgaa tgaagatcgt ctgttattga acatcatatt
     5161 ttttgtcgtt caaaataaaa atgatcgaag gctaggagtg aatttt
//
LOCUS       DAIGWC010000117         5152 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.120, whole genome shotgun sequence.
ACCESSION   DAIGWC010000117 DAIGWC010000000
VERSION     DAIGWC010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.120"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(52..561)
                     /locus_tag="NOB74_002651"
     CDS             complement(52..561)
                     /locus_tag="NOB74_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HCI1221780.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(673..1671)
                     /locus_tag="NOB74_002652"
     CDS             complement(673..1671)
                     /locus_tag="NOB74_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI1221781.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1872..2456
                     /locus_tag="NOB74_002653"
     CDS             1872..2456
                     /locus_tag="NOB74_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI1221782.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(2533..3726)
                     /locus_tag="NOB74_002654"
     CDS             complement(2533..3726)
                     /locus_tag="NOB74_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI1221783.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            3790..4170
                     /locus_tag="NOB74_002655"
     CDS             3790..4170
                     /locus_tag="NOB74_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HCI1221784.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            4244..4606
                     /locus_tag="NOB74_002656"
     CDS             4244..4606
                     /locus_tag="NOB74_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221785.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEGNVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1683 a          891 c          959 g         1619 t
ORIGIN      
        1 aaaaaagaaa gaactcgtct aaatagacgt tttctttctt tttttgttga attattgagt
       61 aaggcgactt cttttttctg gttctttgtg tgctaatcga ctggcagcag cagcggcgat
      121 cgctccgacg atatcatcta agaaggtatg gacatgaacg ccatcgtggc tgtttagttc
      181 ttttaaaata ccaggtttca ccttgtcgat ataaccataa ttcgtaaagc cgatcgtacc
      241 gtaaacattc acgattgaca aggctaggat ctcatcgata ccgtaaaggc cttcgtcatc
      301 ttcgataata tgttgcaacg gactcatcaa ttttttcttt tctgctaata tatctaattg
      361 gattccagtg ataatggcgt tatgtacttc acgctttgtt agcacgctgt tgacactttc
      421 agtacaatcc gccaaagtca aatcagaaat atagtctttt tgtaaaaaca tgacaagttg
      481 tgcgatatct tctacagtta cgccacgttc cttcaatagt tctcttgcct tttcttctaa
      541 agtctcagtt ttgacgacca tattattgct ccccctttat tttttctttc tctatttcat
      601 gttaacggaa catgaaaaaa atgcaagaaa ctgctttcgg gtttaacttg aaatgcaaag
      661 agatataaaa aatcaactag gacgaagatt tttatcgtat aagcttgtgc tgtgaccagg
      721 ctgagttcgt tcctttggat taatatagtg taaagcgttg ttcactgcag taggtgcttc
      781 accgagccca gtagcaatca gtttcacttt tccttcatag gtacagatgt caccagctgc
      841 ataaacgcct ggaatagaag tagacatatc tgattttaca gtaatggcat ttctggtact
      901 atcaagtccc caagaagaaa gatgttctaa attagaagag aatccataat tgacgatcag
      961 agaatcaatc atcaaatcaa tcgtctcgtc acttttcact ttttttaacc ggatatctgt
     1021 cagttcccca ttattgcctg ataatccatc gatgagatag ggagtaagca agttgacaga
     1081 tgaagatttc aagcgtgata cactatgttc gtgcgcacga aattccgggc gacgatgaat
     1141 caagtaaact tcgcttgcaa taggctctaa catcaacgtc caatcgatag cagaatcacc
     1201 acctccagca atagcgactt tttttccagc atacttcatc aaatcattca cgaaataatc
     1261 caatccgtgg ttttcaaatg attcagcatt atctaaattc aattttcttg gctggaatga
     1321 accatttcct aaagctaaaa tgactgcttt ggaataatgg atgcctttat ttgtagtaat
     1381 ctcgataact tcgtcttcac gagtaagcga gagaacttct tcttttaaat ggaatgtatg
     1441 gttaaaagta gttaattgtt tttctaattg atcgattaat tcacttgctt ttattgctgg
     1501 atacccagga atatcgtaaa tatatttttc gggatacaaa gttgctaatt gaccaccaag
     1561 ttgaggtaga ctgtcaatga tttttgtttt agcttggcgc attcctgcgt aaaaagcggc
     1621 aaacatccct acaggacctg caccgatgat tgtaatgtca tagatttcca taaaaattcc
     1681 tcccttttca cactatagca gaatttaatt gagaatgctt ctcaaaaatg tttgaattcg
     1741 aaatcgaaac ggtaagttat agaatgtatc tagtgatgaa aaataaaaga aaacaaatct
     1801 agtattttta cgagaggtta ggtattatgt tattattatt atgaagtatg caaatattag
     1861 gaggaaacaa tatggcattc ccacaactag atttaaaaag tgaaaaagga ccaaaagctg
     1921 ttatcaaaac aaaccgtggt gacattactg ttcaattatt ccctgaacta gcaccgaaga
     1981 cggttcaaaa tttcattgaa ctttccaaaa aaggttatta tgatggcgtg atttttcacc
     2041 gcgttattcc tgatttcatg atccaaggcg gcgatccaac tggaacagga atgggtggcg
     2101 aaagtattta tggcgaaagt tttgaagatg aattcagtcg tgaactgttc aaccttcgcg
     2161 gagctttatc tatggcaaat tcaggtccaa acacaaacgg aagccaattc tttattgtaa
     2221 ataacacaaa tgtgccagct aatatgcttg gacaactaga aggtgctgga ttcccatcag
     2281 aaatcattga agcgtataaa ggtggcggaa ctccttggct agatttccga catacagtct
     2341 ttggacatgt actagaaggg atggacacag tagatgaaat cgcaaatgta caacgtggtc
     2401 cacaagaccg acctgtacat gatgtagtga ttgaaacaat tgaaatttca gaatagtttg
     2461 gtatggtacg gagtaattat gaaaaaggac gaaacctagt aaggtctcgt ccttttattt
     2521 tgaataaatg atttaatcga ttgtctctaa agcatacttg attcgattaa gtccttccag
     2581 taaagtttct tctggacaag caatattcaa gcgcatatgc ccatgaccgg aaggaccaaa
     2641 cgtgatgcca ggatttaata cgacttttcc tttccgaaca agagtgttct ccaattcttg
     2701 gtcgtctgaa atataggcgg taaaatctaa ccacattaag taagttcctt cagggttcat
     2761 tattctcact ttcggaagat actgttcaaa aaactgatta actgtttgaa catttttttc
     2821 tagataagga atcagttggc ttaaccattc tccacccgtc tcataagccg cttgggttcc
     2881 aatcagtcca aaagtgttga tttcgtgctg ttggttcatc actaaatgtt tttcaaaatc
     2941 agctttcatc tctggatttt tgataaatac cattgaattt ttgattgcag ctagattgaa
     3001 agtcttggtt gcggaagtaa aagcaactag tagatcatct aaattaggat caatcgttag
     3061 catggaagta aatgtatgat cgaataaagt taaatcttga tggatctcgt cactaaacag
     3121 aatcacttga tgttttaaac acaattcgct taactgtttc aattcttctt tgctccaaac
     3181 acgccctcca ggattgtgag gattgcataa aatcattgct tttacattgt tttcttcgat
     3241 ttttttctcc atgtcagaca agtccatgat gaaatgatta tttttttcta gcaaagagct
     3301 tcgaacgatg tgacgttgat ttgtttctat aatagaggaa aatggaggat aaactgggtc
     3361 atgaatcaaa atagaatcgc ctggttttgt aaaagtttgt actgctgcag ctaaactggt
     3421 taacacacca cttgtaaaaa cgatattttc tttcgtcaac tccacagcat ggtgttggcg
     3481 ttcccaatga atgatagcct gatatagttt atcagacaga gtggcataac caaagattcc
     3541 atgtttgatg tattcactaa acgctttagc taccccaccg ggagacaaga agtccatatc
     3601 tgctacccac aaaggaagta agtcatccat ttgatatgtc tcagcaattg cgtcccattt
     3661 tacactttct gtatcttttc ttgaaatctg tttatcaaat tcgatcatct taagacctcc
     3721 agtcattttc gtcgcttctt tttttgagct atttacagta taatgataaa tgcgaagaga
     3781 gggaagtaga tgacttataa aattggacaa ataattgaag gaaaagtgac agggatacag
     3841 ccttatggcg cattcgtttc tcttgataac gagacgcaag gacttattca tgtttcagaa
     3901 gtacaatccg gttatacgaa aaatatccat tcattgttaa aagtcggaca gccagtaaca
     3961 gttcagatca tcgacattga tgaatattcc aaaaaaatca gtttatcttt aagaacgtta
     4021 gaaaaaacaa atccagctgt tccatatcgc agaaaaaggt atttcacgaa taaaaatcgt
     4081 aagatcggat ttaccactat tgcggagcag ttacctattt ggatagaaga agcattatct
     4141 gaactagaac ggaaagaaaa taagaaataa aaagtgtatt ttttctgaaa atgtgctaga
     4201 atttttatgt aagccataga acaagttgat cgaggtggaa attttggcaa gcaaaagagt
     4261 tgctggtaca attatgttgc atttggagga tggtactaaa aaatttttgg tccattcaat
     4321 tgatgacaag ttggaatttg cgttagcgga actttctgaa ggaaagactg gtttagcgaa
     4381 tatacttaat ttcttaaaag aaatagttca tatcgatgtt agcaagatta gtttgatgga
     4441 attgacaaat acacatatta aagagggaaa tgttccgttg tttgtctttg aaactgaaca
     4501 aaagaatcaa agagaagaat taggcgaagg atatatttgg gaagaaccag gtcaaatgcg
     4561 ctctgttctt ggaacttacg aagtagaggg agtgcctttc ttctaaaata cagattaagc
     4621 gaacaaagaa gtttgaattt ttttcaaact tcttttttta ttgtttggtc caaaaaatac
     4681 aatgaaatgt tctgctaaag atagtttttt agtgcatttt attttcaaaa tatgttgaaa
     4741 acggttgtat aacgaataat aataattgat cgaaaaatca tttcacaaag taatgcttaa
     4801 tttatagttg accaaggaag aaatacatga taaatttaac agcgttgatt ctgaagtgga
     4861 tgttatatca catttctaaa aaatttaaaa aatagttatt gacatgttac taacgacatg
     4921 ataagataac tgagtcgtta aaaaagaacc acttgcgaag cttgattcta tcgaaaaaaa
     4981 cttcaaaaaa gttcttgaca aataacaaac gataagttat gataaatgag ttgctgaaag
     5041 atttcgaaaa acgaaatcga aaaaaacttt taaaaaagag ttgacaatcg cttgtctctc
     5101 tgatatgata taaaagttgc tacggcagcc aaaaacgaat cgggaaacac tc
//
LOCUS       DAIGWC010000118         5024 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.121, whole genome shotgun sequence.
ACCESSION   DAIGWC010000118 DAIGWC010000000
VERSION     DAIGWC010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.121"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            283..522
                     /locus_tag="NOB74_002657"
     CDS             283..522
                     /locus_tag="NOB74_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221786.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="NOB74_002658"
     CDS             complement(884..1144)
                     /locus_tag="NOB74_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221787.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="NOB74_002659"
     CDS             complement(1329..1826)
                     /locus_tag="NOB74_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HCI1221788.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="NOB74_002660"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="NOB74_002660"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HCI1221789.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="NOB74_002661"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="NOB74_002661"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HCI1221790.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5015)
                     /locus_tag="NOB74_002662"
     CDS             complement(4548..5015)
                     /locus_tag="NOB74_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221791.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT         1528 a         1044 c          770 g         1682 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatcatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgca
//
LOCUS       DAIGWC010000119         4923 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.122, whole genome shotgun sequence.
ACCESSION   DAIGWC010000119 DAIGWC010000000
VERSION     DAIGWC010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4923
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.122"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            83..970
                     /locus_tag="NOB74_002663"
     CDS             83..970
                     /locus_tag="NOB74_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCI1221792.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="NOB74_002664"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="NOB74_002664"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HCI1221793.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="NOB74_002665"
     CDS             2272..2718
                     /locus_tag="NOB74_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI1221794.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="NOB74_002666"
     CDS             2991..4343
                     /locus_tag="NOB74_002666"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HCI1221795.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="NOB74_002667"
     CDS             4514..4801
                     /locus_tag="NOB74_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221796.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1693 a          812 c         1030 g         1388 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 ccc
//
LOCUS       DAIGWC010000120         4797 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.123, whole genome shotgun sequence.
ACCESSION   DAIGWC010000120 DAIGWC010000000
VERSION     DAIGWC010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4797
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.123"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(75..159)
                     /locus_tag="NOB74_002668"
                     /pseudo
     CDS             complement(75..159)
                     /locus_tag="NOB74_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            complement(208..447)
                     /locus_tag="NOB74_002669"
     CDS             complement(208..447)
                     /locus_tag="NOB74_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HCI1221797.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            complement(567..2711)
                     /locus_tag="NOB74_002670"
     CDS             complement(567..2711)
                     /locus_tag="NOB74_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HCI1221798.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFIT
                     FGFGHLVELAEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELLKKANT
                     IIVATDSDREGENIAWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYY
                     PFYQEAQTRQIADWLIGMNASPLYTLNLQQKGVQGTFSLGRVQTPTLYLIFQRQEAIE
                     NFKKEPFFEVEASIKVNQGSFKGVLSPTQRFKTQEELLAFVSSKQAKIGNQEGIIADV
                     QTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITE
                     NEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAIIPTKQVPTESALAK
                     MDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQSIGKTPKQEGWKILFKQ
                     QTKEEKEDVQTLPLVIIGERAEVGVKSVEKETQPPKAFTEGTLLTAMKTANKTVDDEE
                     AIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTS
                     AEMTAKWETYLKKIGKREGNQENFITNIKKFIVHLLEAVPNDIEKLNFSDYQEQKEKE
                     AEKSIVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFRKKKLTKTNVKELLEGKET
                     LVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            complement(2711..3022)
                     /locus_tag="NOB74_002671"
     CDS             complement(2711..3022)
                     /locus_tag="NOB74_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1221799.1"
                     /translation="MFWKIKKMLVSSTNIKKYRAKKIKERQAQGIEIAKKKGKFKGRQ
                     HKFKENDPRLKHAFDLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRD
                     S"
     gene            3089..4381
                     /locus_tag="NOB74_002672"
     CDS             3089..4381
                     /locus_tag="NOB74_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI1221800.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSECRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            complement(4461..4797)
                     /locus_tag="NOB74_002673"
                     /pseudo
     CDS             complement(4461..4797)
                     /locus_tag="NOB74_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT         1342 a          958 c          762 g         1735 t
ORIGIN      
        1 gatttgtttg taattttagt tatctgttta aaaagtcata agattagtca ctggtaggaa
       61 ttaatctaac gtatttattt atctgtgtaa tcactgtttt ttagtctgtt tcaaaacagt
      121 agatgtttta tctacattac gcatttggaa taccaacatg acgaatccct ccttcttaat
      181 tacaaatttt tagcatctaa tttaacttca attcctatta tacaaaattt taagataatg
      241 cactatcaac acactcttaa gtttgcttct aagtcttatt tccataactt cttttacgtt
      301 tccgccattc tttgctgttt cgatttttat gatatggtgc aagtcagcac gaacacgaac
      361 cgtcttatct cccattatat ctttttttgc actgattggt gtatcatttc gtttttcttt
      421 ttgtgcgcct aaatttccca caatcactca cttctttcta tttcttctta ttcttatttt
      481 atcatcaaca atcacaaatc acttgtgatt tgtgataagt gatttgtgat taatatataa
      541 aagccctctt taaagggctt ttatgtttat tttgagaaag atataaaatc aatatatccc
      601 ttttccccaa tttttacaac ggcattgtag ggctttttct ctttgttttt gattcctttt
      661 accagggttt cttttccctc cagtaattct tttacattcg ttttggttag ttttttcttt
      721 ctaaaatgtt cagctaaagt aaacttacat tcaggataat ttgaacaacc ataaaacgat
      781 ttttttaata caatattgtt gccacactta ggacattttc ctacaatact tttttctgct
      841 tctttttctt tctgttcctg gtaatcagaa aaatttagtt tttctatatc gttaggtaca
      901 gcttccagta aatgaacaat gaattttttg atattcgtaa taaagttctc ttgattgcct
      961 tctcttttac cgattttttt taaatacgtt tcccatttag ccgtcatttc agcactcgtt
     1021 aaaaggtgct gactttcaac tgcctggcac aataattttc ctttttcagt tacaacaagc
     1081 ttattcttaa tcacttggat atattctttt tgttttaacg cttcaataat acttgctctt
     1141 gtcgcttctg ttccaatccc ctcaacttct tgtaaaatct tgattgcttc ttcatcatca
     1201 accgttttat tcgccgtttt catagcagtt aataatgtac cctctgtaaa agcttttggc
     1261 ggttgcgttt ctttttcaac actcttaaca ccaacttcgg cacgttcgcc aatgataacg
     1321 agtggtaacg tttgaacgtc ctctttttct tctttggttt gttgtttgaa aagaattttc
     1381 cacccttctt gctttggtgt ctttccgatc gattgaaaca gcaaatcagc tactttcgtt
     1441 tgtatcttgg tttcttcata caagtaatca ggtaaaaaca tggcaacggt cgttttaacg
     1501 actaaagcat aaatttttcg ttgtaaatcg tccattttcg ctaatgcaga ttcggtaggt
     1561 acttgttttg ttgggataat ggcgtggtgt tcctgtacct tactaccgtc cacataacgc
     1621 tttctaggct ctgtttgaac catttcaaga tcaagtccta aaaaaccgct atatttgcca
     1681 aaattcgctt ttaaataagc aaattcgttc tctgtaataa atggtgtatc tgttcttgga
     1741 taactcaata attttgcttc atacagtcct tgcatagctt ttaaagtttg gctcgctgtc
     1801 gctttataaa gctgattgac ttttgattgc aaactactta aagaaaacaa actcggacta
     1861 ttcgttttct tctctttggt ttgaacatca gcaattatcc cctcttgatt gcctatttta
     1921 gcttgtttag aagaaacaaa agctaaaagc tcctcttggg ttttaaaacg ctgtgtgggg
     1981 cttagaacgc ccttaaacga cccttggttt acttttatac tagcttccac ctcgaaaaaa
     2041 ggttcttttt taaaattctc tatggcttcc tggcgctgaa aaataaggta taaggtgggc
     2101 gtttgaacac gtcctagtga aaatgtacct tgtacgccct tctgttgtaa atttaacgta
     2161 tacaaagggc ttgcgttcat gccgatcaac caatcggcaa tttggcgtgt ttgcgcttct
     2221 tgataaaagg gatagtaatt cattccaggt tgcaaatttt gaaaaccgct tcggattaca
     2281 tctttttcta agctattgat ccatagtctt ttaaatgttt tatcttttga aaaggcattt
     2341 gctttatgga taatcgacca ggcgatattt tcaccttctc tgtcgctatc tgttgcaaca
     2401 ataattgtat ttgccttttt gagaagttct gcaacaattt taaactgctt tcccttatct
     2461 tttgcaactt caaaatcgta tcgatcagga aaaatcggca aagattcaag tttccaattt
     2521 tgccactttt cgtcataatg acctggttct gctaattcca ctaaatgccc aaaaccaaag
     2581 gtgataaacg tttcatctgt aaatagtggg tctttgatct caaaataacc gtcttttttg
     2641 gtgctttgtt ttaaagcact tgcgtaggct aatgcctggc ttggtttttc agctaaaata
     2701 accgtactca ttaactatcc ctcttttcat tgttttttct ttgatcgact gtcacgttat
     2761 atcttgctcg ataccttcta aacgttcggc gattgattcc agtttgttct tcaacttctt
     2821 tatcggataa accattcaaa aacaaatcga aagcatgctt taaacgtgga tcattttctt
     2881 taaatttatg ctgacgacct ttgaatttgc cttttttctt agcaatttcg attccttgtg
     2941 cctgacgttc cttaattttt ttagctctat actttttgat gttggtggat gacaccagca
     3001 tcttttttat tttccaaaac atatagaaaa gacaccttga aatcctttag aattaatttg
     3061 gcgaaccaac ccaaaaggag gaatcaagat gtcttacact caccttatca aagaaacatt
     3121 agatattcta gacttatcag ttacttttaa cgaaaattgt ctcacaaaag aaaaatacaa
     3181 agggcaaatc tgtcatattt atcgtggaaa cttgatttat acagcccaag aatgcatcca
     3241 ctgtaaacac cagattgctt cagatattgt gcgttggggt acaacaaccg tccggttgtt
     3301 aatgaacgat gtttctgaat gccgtaccta cctcgaattg aaaaagcaac gcttcaaatg
     3361 caaagcttgt cagcggacct ttgtcgcaga tacttctgtt gcgaaaaaac actgtttcat
     3421 cagtgagaaa gtccgctggt ctgtcgtgac tcgtctgaaa aaaaatacct caatgacaga
     3481 gatcgccgct cagaaaaatc tatcggtctc ttctgtttac cgtattatga agcgatttta
     3541 tcgtccgttg aatccttttc ggacaccgtt acctaaggta ctttgttttg atgaattcaa
     3601 atcagttcgg ggtgtttcag gtgctatgag tttcatcatg atggatggac aaacacagcg
     3661 cttgttggac attgtcgaga accgacaact gcctttttta aaacgttatt ttagtcattt
     3721 ttcacgagaa attcgtgaag cggtcgaatg gatcgtgatt gatatgtacg ctccttatgt
     3781 atcgctcgtt aaaaagctgt ttccaaaagc acagctgatt attgaccggt ttcacatcgt
     3841 ccaacatatt ggtcgtacct ttcgcaatca tcgaatcaaa gaaacgaacc aactattaaa
     3901 aagcaaagaa caaaaacact atcaattagg taagcaatta aaaagatact ggaaacttct
     3961 tcaaaaagat gaacgcaagc ttgattatac tcgacgcctt tggcgacctg gcttcaaagc
     4021 tcatttaaca gagaccgata ttgtggatcg cttactgaaa gggagccctg ctttgcgtgt
     4081 aggctatcag ttatatcaag actttcttta cgctgtaaag gaacgagact acgtatcgtt
     4141 tgaagaacta cttaccaata atatcatgct tcccgaaggc tatcagacga ccttgagaac
     4201 gttccagaaa tttctgccac aaatcaaaaa tgctttacaa caaagttatt caaatggccc
     4261 acttgaatgt ctgaacaacc atatcaaagt gttaaaacga aatgcatatg gctttcgtag
     4321 cttttataat ttcaaattgc gcatcatgat tcgtcatggc aacgcattga ttttcaacta
     4381 aaaaagatca agaggaactg atccacttga tctccaatta ttctaagatt tctctttacc
     4441 aacatcattt gacaaagagc catttttttt cgttctgatt ctgcttgata cttgtacaat
     4501 tcaatgacaa ggctattaat caaacgcctt aaattttcat cttcaatacc attcattgag
     4561 ggtaaattta agacttccag ggttgccccc ttaatttgaa tttgattcat caattctgtt
     4621 aattctttat tatttcgtcc taatcgatct aattcagtaa caataacaat atccccttca
     4681 cgaatatagt taagcatagc ttgtaattgt gggcgttcga ccgattgacc gcttaatttg
     4741 tctgaaaaga ccttagaaac gccctgtaac gcttgtaatt gccgatctaa gttctgt
//
LOCUS       DAIGWC010000121         4760 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.124, whole genome shotgun sequence.
ACCESSION   DAIGWC010000121 DAIGWC010000000
VERSION     DAIGWC010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.124"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(18..413)
                     /locus_tag="NOB74_002674"
     CDS             complement(18..413)
                     /locus_tag="NOB74_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221801.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
     gene            complement(403..615)
                     /locus_tag="NOB74_002675"
     CDS             complement(403..615)
                     /locus_tag="NOB74_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1221802.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            1687..2289
                     /locus_tag="NOB74_002676"
     CDS             1687..2289
                     /locus_tag="NOB74_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221803.1"
                     /translation="MEDIILRDRLTDPLKNSLANVIYDILREADKVYSNYNGKVSWVI
                     YSFLIKEFFKEQINNSYELGYHFTVYYEDIIKRLEDLEWYAYYDLLEVFASAKILDKK
                     KREEVNKILESENSGYRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYI
                     SEKENQDYNTVVREAISAVESCLIEFSGLPANKKILWELL"
     gene            2644..2880
                     /locus_tag="NOB74_002677"
     CDS             2644..2880
                     /locus_tag="NOB74_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HCI1221804.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            2877..3290
                     /locus_tag="NOB74_002678"
     CDS             2877..3290
                     /locus_tag="NOB74_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCI1221805.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            3809..4759
                     /locus_tag="NOB74_002679"
     CDS             3809..4759
                     /locus_tag="NOB74_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HCI1221806.1"
                     /translation="MERNSENKMTGRNPKVFISYSWENKENKEWARELADKLLENGID
                     AYIDQYDLSLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAEL
                     LSGKNERKFIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKP
                     ALGDIPRHIKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRV
                     PSQLWKELFVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIE
                     KSNTQEKKILLEEEQKKERENERVRSHKESVQKLADELEF"
BASE COUNT         1755 a          647 c          801 g         1557 t
ORIGIN      
        1 tgtatgaacc tttatttcta catttttttc tcaagcacac tactgataat gattaaaata
       61 atcggctgga ttgcaatgat acttccgaca ataatagctg gaatgatgta gtctaaacaa
      121 ataaatataa ctgttgccac ccctaacagt attgtgttaa acatatttgt tatatttccc
      181 gctttttctt tgattatgat attccgttcg tccataacat tgattttgta gtctgcatca
      241 tttttaatca ttttatcatg caaaatttga acatgagaaa cgccaaaaac ggcactgaat
      301 aaaatagcaa gtccaatatc taccatttta ggaaaatctg taaccaaaat tgtcacaatc
      361 aaaaacaacg aaacaatata accgatatac caaatctgac ccttattttt catcttcact
      421 ttcctcctca tagataaaaa tttcttcaat gctcatttga aagtaccttg caattttaaa
      481 tgccaatata atagagggat tataacgtcc attttctaaa gaacctattg tttgacgaga
      541 tacttcaaga gcagaagcta aatcttcttg tttaattcct ctttgttttc gtaattcttc
      601 caaacgattt ttcacaacat gctcctttct aaaaaatgga aagtttactt tcctttcgtg
      661 cttttataat actcctgcga gcacaaaatg tcaaggaagc tttccgtata aattttgatt
      721 ttaatgtttt agttactgtt tttatgacac atgaacacac ttattcttat ttcctcttat
      781 ctgctatcaa cagaaaagaa aaagccctgt caagagccga ttagatcaag ccagtcgaga
      841 aacgatgtta gaccaaattg attttgggta atgaatgttt agaacttagt agtcatccaa
      901 aaacgactac tttttttgtt gaatcgtcca aggacgattc gatgcttttg acttgtaaga
      961 acaggattga atgaaaccat actgttcgca tatttttagt ggatgaacaa acaaaatacg
     1021 agagattttt tgttcgttca tccatggttt tagaaaaaag agggacgatt ttggaagaag
     1081 aaaatcgtct cttttttttc ttctttttgt atgacaaaaa gaaagatctt ttgcccattt
     1141 tatttttata aaatgggtag gtggcgttcg cgtaaagcaa atcgatacaa tccaatggtt
     1201 ttggcgaatc agatttacca ttctaggctt gtttaataca gacatcgatt gttattttga
     1261 gaatttatat ccttattggc aatgaaatgg atattctcca taccaataga aatcttcaag
     1321 ataattttcg gaaatatata agagttaatc aattatgatc atatagtagg taaaaattag
     1381 gacagccttc aattatatgg gaaaccaata taatcaagta attattcggg taacacaaat
     1441 actagagtac tcatttctta taactgtttt acacctatta gggatcagta ttattaatag
     1501 atctagataa attaatacgt aattatataa taatttatgt ttgtgccatt aaacaatctt
     1561 aacagatatt tcattttatt tatgtaaaac aacacgaata attattgctt cgtaaagtta
     1621 tatgagtata agttaattta ctggaggtag tgcaatgctt ttttctgaaa gatttggttt
     1681 taaaaaatgg aggatatcat actgagagat agattgacag accctcttaa aaatagttta
     1741 gcaaatgtga tttatgatat attacgagag gctgataaag tttatagtaa ttataatgga
     1801 aaagtctcat gggtaatata ttctttttta attaaagagt tttttaaaga acagataaat
     1861 aatagctatg agttgggtta tcattttact gtttattatg aagatattat caagaggtta
     1921 gaagacttgg agtggtatgc ttattatgat ttattagagg tttttgcaag tgctaaaatc
     1981 ttggataaaa agaaaagaga ggaagtaaat aaaattctgg agtcggaaaa ttctggttac
     2041 agattaagcg aaagcaatga atttattcca atcacagatg atatttctat taagtctata
     2101 aatgctgtat ctgaatcacc atttaattac gcaaaaaatc atatccataa atctcttaca
     2161 tatataagcg agaaggaaaa tcaagattat aatactgtag tgagagaagc aattagtgct
     2221 gtcgaaagtt gtcttatcga attttcagga ttaccagcta ataaaaaaat actttgggaa
     2281 ctgctataaa agcaattaaa gacaaatcga ataacaatgt cgatcttaca tttttaaaac
     2341 catttgagac aatgtatggt ttggcgagta ataatggaat acgacatgca gaaaatgaaa
     2401 aaacaattgt ctcagattta cctgatgcag ttttggtgtt aacaacatgt tcagccgtaa
     2461 ttaattattt gggagtaaaa atagcatatg actccaataa atcatgaaaa gttaaaattc
     2521 atccaagagc tacattataa ctattaattt ccaactcttt aaaagtttag taattgaagg
     2581 aagtaataag ggtgattgaa caatacggat atacggtgta tacttatcgt aggagttgat
     2641 gatatgaata ttaaaaaacg caaaatcaga gaagtaggta attcaatagt tgtaactttg
     2701 tcaaaagaga gtttattgca aaaaggtttg aaacctggag atactatttt tattgatgaa
     2761 gataaaatga tggaagctat tgtaaaagag gaaagcaaga tagatcttga aattgatatg
     2821 tatgttaacc aagctttatc tgagtatgat gcagctttca aggaattagt tgaaaaatga
     2881 tctatctaag tgaaaaagat attgtaaaat tgaatgttat tcaaataaag aaatattcac
     2941 cgcgagaaac aatcggagtc attgacaaaa atgcgctgag tatggctgta aatcaaccta
     3001 aacagcatat ttttggaaaa gatctgtatc ctgataaatt tagcaaagca gctgttctgc
     3061 taataaatct gatcaaaaag catccatttc ataatgctaa caaacgtaca gcatttttag
     3121 ccgcgtatgt ttttctcaag ctaaatggct attcactaaa aatgaaaaat caggaagtag
     3181 tagaatttgt agttgaaatt gctacgtatc agggtgattt tgatgactta aaagaggcaa
     3241 caacagatat actaaaaaag aattcaacaa agaccgattc aaaaaagtag aagcaaacta
     3301 gggattcagt taaatctgaa gatttagttt gttctttatt ttagtttaca taagatacat
     3361 tatgcgaagt tcattatttt aaaagcttaa ataataaact tttttataat accaatttat
     3421 ttatgtaaac caatgacctt aatcgcttaa gcaagcatgt tatgtaatac tctactctct
     3481 ccaaaactaa tgactatcta ttttcaaaga agctagaatg attatctgat caaatgataa
     3541 tttatattta attcctggtc tactgctctt cttttaatca attaatgtct aacgtactgt
     3601 acacgataaa gtaggaagac ttattttcaa cttcggattc atttttttaa ttcggtgaaa
     3661 atcactaaat taagagttta tccaagttca ttttagctga gaatacgctt gaaaataatt
     3721 ttgatgaatt ttcctgaatt aaaatttatt aacttgttga gtgatataat tgtaatgtat
     3781 taccaaatag ttagcactta gattagtgat ggaaaggaat agtgagaaca agatgactgg
     3841 tagaaatccc aaagtattta tatcatattc atgggagaat aaggaaaata aagaatgggc
     3901 tagagaacta gcagacaaat tacttgaaaa cggtattgat gcatatatag atcagtatga
     3961 tttaagttta ggtgatagat tacctcagtt tatggagcag caaatatccg attcagatta
     4021 tgttctaatt atatgtacac cagagtataa aaaaaaggca aataatcgta caagtggtgt
     4081 tgggtatgaa ggtcatatta tctcagcaga attgctttct ggaaaaaatg aacgtaaatt
     4141 tatcccaata attaaagaag gacgtgcaag cgaagtactt cctacttttc ttgctggaaa
     4201 gcttggaatt gatttatcag atagccagca ttatgatgaa aacttagatg atttaattac
     4261 aactatattt ggtgttaaga gaaaaccagc attaggtgat atacctaggc atattaaagg
     4321 cagtccttta ctacctatag aacataatga aaataaagat attgaaatct taggaattat
     4381 cactgataaa gtaactgtac ctaaaatgga tggctcaagg ggttctgcat tatataaaat
     4441 tccatttaga ttaaatagag taccaagtca gctttggaaa gagttgtttg ttagaaattg
     4501 gaattcacca ccacgatata caacaatgca tagaccagga attgcttctg ttgtagacga
     4561 tgaaatttta cttaatggaa caactattga ggaagtccgg gaatatcatc gggaaacttt
     4621 aaaactttgc attgaaaaaa gtaatactca agaaaaaaaa atattgctag aggaggaaca
     4681 aaaaaaagag agagagaatg agcgagtcag atcacataaa gaaagtgttc agaaattagc
     4741 agatgaatta gagttctagt
//
LOCUS       DAIGWC010000122         4754 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.125, whole genome shotgun sequence.
ACCESSION   DAIGWC010000122 DAIGWC010000000
VERSION     DAIGWC010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.125"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..1131)
                     /locus_tag="NOB74_002680"
     CDS             complement(<1..1131)
                     /locus_tag="NOB74_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI1221807.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDD"
     gene            complement(1261..2637)
                     /locus_tag="NOB74_002681"
     CDS             complement(1261..2637)
                     /locus_tag="NOB74_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1221808.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2637..3293)
                     /locus_tag="NOB74_002682"
     CDS             complement(2637..3293)
                     /locus_tag="NOB74_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1221809.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3303..4580)
                     /locus_tag="NOB74_002683"
     CDS             complement(3303..4580)
                     /locus_tag="NOB74_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1221810.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(4599..>4754)
                     /locus_tag="NOB74_002684"
     CDS             complement(4599..>4754)
                     /locus_tag="NOB74_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCI1221811.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
BASE COUNT         1487 a          865 c          572 g         1830 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgcgcattc tcattagaga acactccctt
       61 ttttgtgact tttctgaagc tagagtgaat actttcaact gcattagtag tgtacatgat
      121 ttttctaatg gcgctgccat aatcaaagag ttgttcaaca tgagaaaagt ttcgtttgca
      181 tacatctact gcaccagaat aatgagacca ccgattttga aaactgtcga aggcagcgtg
      241 tgcagcgttt aaagaagaag cactgtagaa ttttttcatg tctcgacaga cttccttata
      301 atccttactt gggaggtatc gtaacgcatt tcgaacaaga tgaacaatac agcgctgcac
      361 aatgacagaa ggaaaaattg cttttgcgcc ttctttgaga ccggaaacac cgtccatcga
      421 aatgaaaaaa acatcttcta caccacgtac tttcagttca tcaaatactt gcatccagcg
      481 atttttagat tctgtttgat tgagccatag gcctaaaatc tccttgtttc ctttaagatc
      541 atagccaaga atggtgtaca cagcatattc tttagcttca tagttttcgc gtaaagtgac
      601 gtacatacaa tcaacgaata gaaatgcata acacttggct aatggccgag cttgccattc
      661 ttccaattca ggaaggacgg catccgtgat atcagaaatc atttcgtggg aaatatcaaa
      721 gccgtaaata tcttcaacgg ttgcggcgat atcgcattga ctcattcctc gtgcatacat
      781 ggaaagaacc ttaccttcga tgtcggagac atctcgtttt ctattaggaa tcaactcagg
      841 ttcaaaagaa gcctcccggt ctctgggaac atcaatgttt actttaccaa agctcgtttt
      901 aagcgtctta ttgccataac cgtttcgtcg attgtcatgt ttctttggct ctttagaatg
      961 ggcgtcatac cctaaatggt tattcaattc tccttgaagc attttttcaa ataagggacc
     1021 aaacacatct tttaaaacat cttgcatatc ctctacagat tcgggttgat aagtattcaa
     1081 aatggattca gctaacttct cagcatcagg atttcttttc tttctagcca tcgtgtaatc
     1141 acctcttgat cttattttag aaaaataaaa accgtgaagc aaccacccgc ctaggattga
     1201 tggttactta cacggtttat attacactct catttttggt gctaaaaagc accgaaaatt
     1261 ttaattattg tcaattaata attcttttgg attccttctt aatatattga atgaagaaat
     1321 aatcaatgat acaagaagta ctaaactcat aaatataact acataaatca tgaatttagg
     1381 taatacattg atatctaaac ttgataatgt cttgttaaat ccttcagctt ctgccccacc
     1441 acctaattgg ctagatgcag attgtttagc tatttgttta gctatatcac cagtaacctt
     1501 attcaatata ttattcccaa gcttgtcagc tgtatattga gctaagaaat aggaaccaac
     1561 gaatgcgggg attgatataa ataccatctc aattaggaat tgaccaaaaa tttctaattt
     1621 tgatatacct aatgatagta atactgctat ttctttcttt ctagcattca tccataagaa
     1681 taataataat gaaactacaa ctcctgcaaa tattaatgag ccaaaaaata atttatttga
     1741 aattgagtaa atacctgata tagattgttg taatgcaggg taatttgatg aacttttaat
     1801 caaattatat tctctccaat ttatatctaa tttcccaaga tcttttatta cactatcaag
     1861 attcttatca ccttttacaa agaatgttgc atcttggtat acagctgtat cttcggtatt
     1921 accataaact ttagcagctg tatgaatatc agtgattaat gtattttcgt atagttcttg
     1981 tgctgcactt actccaccgc tattatgccc atcgaataga cctttaattt ctacttctac
     2041 tgtttcatct gcacctttct cattatcagc atcaaataaa ttagatttta tttttatctt
     2101 atctccaact ttaaggttat ttttttcagc taaatcttta tgcattaaga ttttattttt
     2161 atcttcattt tctaaatgct ttccttctac taatttatat gcttctgata caaattttgt
     2221 ttcttttgtt gagtcgttaa ccccagttaa cataactgtt cttttaaaat tctttgctct
     2281 ttcaggtgat tgattcgcaa gagtctcttg agtttcaata atatcataat caactaaatc
     2341 tgcaacactg tttattcttt ttacatagga gtctatacta tctgtttgag atatcttttt
     2401 aatatcttca ccttttacat ttcccccacc tctaggtgtt cctggattta cttgtctatt
     2461 tatctccata gaaaaactat ttgttatatt agcaaatgtt tcttttgaag ctctgtccgt
     2521 agcatcttta atagataaac taatgagact taaagttgac atagataaaa taactaatat
     2581 gataattaat gattttaaac tttttctagt tacataagca aatgcatttt ttatcattat
     2641 tcaacctcca aattcatttt atttactttt ttcaactttt taccacttag ttctaaaatg
     2701 atatccgcag aatctgctac ttccttacta tgtgttacaa ctattacaca tttatttcta
     2761 tctttagcta atgtctttaa tatattaatt atttctccag cagtaacact gtctagatta
     2821 ccagtaggct catcagctag tattattgga gcatctgata ccaatgctct agcaatagct
     2881 actctttgtt gctgtccacc agataatttc ataacatttc tttttatttg ttttttatct
     2941 aaacctagtt caaacaagat actttcatct gctgatttat ttactaatct aatattttca
     3001 attggtgata aataatctat taaattatag ttttgaaata ctaaagatat attatttttt
     3061 ctatgattac tatatccttt attttgtata tcttcattct taaacaatat ttttcctgtt
     3121 tgaggtttat caagtccagc aagtaaggaa agaagtgtag attttcctgt tcctgacttt
     3181 cctactatcg cataaaactt cccaagttca aatttttgat ttactcctga caaaactttt
     3241 tctttagaat ttgcataact atatgctaca ttctttattt ctaatatatc cattattttc
     3301 tcctaactta tttttgataa gatttcttta ggcttcttga ttaacattaa tgaagaagca
     3361 aatacaactg ataaaacaat aatacttatt aatattaaat aactttgtcc aagtgttgtt
     3421 atatttgaca taaaactact attatttatt aaacttccac cggaaatcat tgaatcctct
     3481 gagttaatga atccatctac aattactttt agtaatacat ttcctaaaaa taaggaagat
     3541 attatacttg gtatcgatat gaatattaac tcgaatataa attgcattat aatttgtatc
     3601 ttagatgttc caatagataa gaatatacct atttcataaa ttctttccct taaccataga
     3661 atcaagatta atgaaagaac aaccatccca cctaacataa tagaataagt cattactttt
     3721 attatatatt ttattccact cactgactct aaagactctt caaacgcatt agaatctttt
     3781 tcaacaaaat actttgactc atcaatttta agctctttca atttgtttaa ggctaagtct
     3841 gtagattctg cactaccaga atacattaaa attttatttg caatttcatt attttctgaa
     3901 ttatttaata tctcttggct tgttgaataa tctacaaaca ccatattttc actaaaatca
     3961 gaagataatc ctgtatatgt ttcctgtttt ttaccagaaa agatccctat aattttaaat
     4021 ttatgacttt ttatttttcc acttttttca atatctagta attcaagatc aacttcatca
     4081 cctaatttta gattgttttg tttagcaaat tcttcatgaa caataattga attcttatca
     4141 ttttcttcta tatttttacc ttctttaatt gtaaatactc cactactaaa taaaatattt
     4201 cttttagtat tatttgtagc ttcgagtgaa acaacattct taaattcgtc agataaatct
     4261 tctctattta ttctttgttc tccgctaact actttagcat cttttagttt tgctaatcca
     4321 tcatattgaa ttattttttc ttcaatttct tttaattttt caatatcttt aaattgatta
     4381 acattaaaat atttaccatc tttttttgtt attgatattg aagaattaga actttcatat
     4441 aaagcctttt ctatttcatt gcttgatttc attattgtta aacaagaata caagcaagaa
     4501 agaactatag ttaatatgat aaaaattatt aaagttctat ttttctttct tgtaatatat
     4561 gctatagcat tttttatcac tttcctaact actcctctct attttcttac tccataacta
     4621 attgcatcca ctggacaagc atttttacat cgtccacatc tgatacactc cagatgattg
     4681 caattctcaa ctgaatcttt attcatttgg caaacttttt tacattttcc acaattaata
     4741 cacttatcct tatc
//
LOCUS       DAIGWC010000123         4735 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.126, whole genome shotgun sequence.
ACCESSION   DAIGWC010000123 DAIGWC010000000
VERSION     DAIGWC010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.126"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            62..1150
                     /locus_tag="NOB74_002685"
     CDS             62..1150
                     /locus_tag="NOB74_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221812.1"
                     /translation="MYSKNWKKKLVMGVMVGSIFVFAGCSASTDKSKTATSETKTAEV
                     VKSKMKQIEKNVEKILAEKDKDTKLSEYKKFVTESSAYSKSDKTEKKITNTYTESIKK
                     IKTNFKEQDDKDLKENTLDNLEEATENDLSQKVNTLDELKKWVQKESTDVYSQAEVDS
                     LIKKIDDTITTYKNQLEKIKIDNQEATSTETTTESSEVATLQENVSEEPQVVHTNLLN
                     SIEEAAQYLGQKLPQSGGSDAFENGQQNSDGSFTFHYQLHGGPEGITWNIITVNNNGE
                     IIQDDYFKTVPNEATNNNVSTLSQAAISELEAAQLAIAKHNELGRPNATDAGSETTAD
                     GYYFYYMADGTDQMYKYFVSNSGQVQAE"
     gene            complement(1607..1774)
                     /locus_tag="NOB74_002686"
     CDS             complement(1607..1774)
                     /locus_tag="NOB74_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017368673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HCI1221813.1"
                     /translation="MSIREIVRIQSFPDSYIFVGSSLSAKYKVIGNAVLPKLAKVIGD
                     SIVKQLSESNF"
     gene            1819..2241
                     /locus_tag="NOB74_002687"
                     /pseudo
     CDS             1819..2241
                     /locus_tag="NOB74_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752995.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3562..4647
                     /gene="xerS"
                     /locus_tag="NOB74_002688"
     CDS             3562..4647
                     /gene="xerS"
                     /locus_tag="NOB74_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HCI1221814.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT         1804 a          724 c          728 g         1479 t
ORIGIN      
        1 aatataacca cttttatgaa aagatgttat aattaactaa aaaataatag ggagaaaaca
       61 catgtactca aagaattgga aaaaaaagtt agtgatgggt gttatggtag ggtctatttt
      121 tgtttttgca ggttgttcag cttcgacaga caaaagtaaa acggctactt cagaaacaaa
      181 aactgctgaa gtagtaaaaa gtaaaatgaa acaaatagaa aaaaatgtag agaaaatttt
      241 agccgaaaaa gataaagata caaaactgtc ggagtacaaa aaatttgtta ctgaatccag
      301 tgcttactct aagtcagata aaacggagaa aaaaattact aatacctata cagaatctat
      361 taagaagatc aaaacaaatt ttaaagaaca agacgataaa gacttaaaag agaatacact
      421 agataatctt gaagaagcaa ctgaaaatga tctttctcaa aaagtaaata cattagatga
      481 actcaaaaaa tgggtacaaa aagagagtac tgatgtatat agccaagcgg aagtagattc
      541 attaatcaaa aaaattgacg atacaattac cacatataaa aaccaactag agaaaataaa
      601 aattgataat caggaggcta catcaacaga gactacaaca gaaagtagtg aggtagctac
      661 tttacaagaa aatgtttccg aagaaccaca agtggtccac acgaatttat taaattctat
      721 tgaagaagca gctcaatatc tgggacaaaa acttccacaa tcgggcggtt cagatgcatt
      781 tgaaaatggg caacaaaatt ctgatggctc gtttactttt cattatcaac tacatggagg
      841 tccagaaggt atcacttgga atatcattac agtgaataat aatggtgaga ttatccaaga
      901 tgattatttc aaaactgtac ccaatgaagc aacaaacaat aatgtctcta cacttagtca
      961 agcagctatt tcagagttag aagctgctca acttgcaata gctaaacaca atgagttagg
     1021 tagacctaat gcaactgatg ccggaagcga aactacagca gacggatatt atttttatta
     1081 tatggccgat ggaactgatc agatgtataa atattttgta agtaattctg gtcaagttca
     1141 agcagaataa cattgagtta taatgatatt atcagatgaa ctgtatcata aatttttaac
     1201 gtgaaatgtt tgtaatatca attggagaat ggtatatgga tttactaaaa gataataact
     1261 gttatttttt agtaaattca tactatttag aaaagaataa tttgctgaat acttgtaaac
     1321 tatgtgtgat acttatctta tatggatata gactcgtggt gctagttaat ttcagcttat
     1381 tataaaccaa cattttcatt ttataaaaac gactaaaaac agaatttctg agtaaaattt
     1441 caaaagtaaa aatagtgata ttatgctctt gttcctagat tcaataatta actagcacca
     1501 cgagtttata aaattggcaa taaaatttta atcattatta acataacctg gatctgtaaa
     1561 gcaatttaac tcttaataaa aaagcatcta aaaaaagcgt gttcagctaa aagtttgatt
     1621 cagaaagttg tttaactata gaatcaccaa ttacttttgc aagttttggt agaacagcat
     1681 taccaattac tttatatttt gctgaaagag agctaccgac aaaaatataa ctatctggaa
     1741 atgactgaat tctcactatc tctcttatcg acactcttag atgaactcaa aaaaatgggt
     1801 acaaaaagag aatactgatg tatatagtca actagaaata tcgctcatag agtgcgtgtt
     1861 cgaggtcgaa aagaaatctg tgaggagttc aaattgattt accatgcgaa ttcaaaagaa
     1921 gaggcattga attacatcga ttttatgatt aggaaatgga aaaagcagga tcgaagagtc
     1981 gtgaacctac tcttgaatcc tgccctatta accttttata atttccctta cgctatcaga
     2041 cgaacaattt attcaacgaa cctgattgaa ggctttaata agcagctaaa acgatatact
     2101 cgaagaaaag aacaattccc taatgaagaa tctctctaga gattcttagc ttcgcaattc
     2161 aactaatata accagaaatt tttaagtaga gttcacaaaa gatttaaaga aattcaagat
     2221 acattagagt cgatgattta actgtaatta acagaatgga ttttccattt acacataatt
     2281 cttgacgcta cctcataata attaagagct ttaaaattag tatttattag atacttaaaa
     2341 gctattttag tattgataaa ttgttaccag caacaaaaaa gaagttactt agtgctaact
     2401 tttgagcaac tgctagagga ggtaggatat ggctaattat cctgtaattt ttattgtatt
     2461 ttctagaaat gtaattattc tcttaaacat tccagcatat ccaagtatat agaaaattta
     2521 cgttttctat atagttggat gtttacaagt tatatctggt ttaataagtt tttttctgtt
     2581 agtcatggca tgttttattg tgctggttca tcaatatatt gaaatgtact aaaatgaaat
     2641 tttcagttat ggtataatat ttatgctgtc tgctaccccg gcctattatg gcaaggggag
     2701 gaggttgtat tatgaattac cttttcgata tgttttttgc aatcttagca gaagtatccg
     2761 cgcattacat ctgtaaatgg cttgattgca aaattattgc caaaaaagac agtaagccta
     2821 cccgttaatc tgaatagaac gtaaaagaaa accactagcc cgccagctag tggtttttgg
     2881 tgtatcatga attacctttt cgttaaaaca attataccat atttcctaaa aaatacaatt
     2941 aatagacgaa ttatcattac cactttgatg aaaaaagctg acataaattt ttcttttatt
     3001 tttataatga ataaacattt atcaataagc ttttgaaagg caggatcgta ctttgttgat
     3061 gattgagata ttgctacatc aatctcagca gttaagattt ttttgaattg ttgcttgaat
     3121 tttttcttta tctaaaaaaa ttgtatctcc aggatgcaac ccattttctt taagaaattc
     3181 cttttaaatt gttaatacta ctgagtgccc cacttctctg aattttcttt aacttctccc
     3241 tccccttttt tatttgtata tacattcata tacgcttgtt aatatcaaat caaccgtagt
     3301 ctctcttatg tctaattata tagaaagatt gttctttcta tataatttag acaatttaaa
     3361 aaattaagat tgcctccttc tgtttccttt cctattcatg tataccattt attttaaatt
     3421 attaaatcta tacctattta tctgcttttt tgaaataaat taataaattt cagagtatac
     3481 caattgacaa aacactctat aattggtata gtccaattat agagatactc ctctccccta
     3541 cttatcgaaa ggatgaataa catgaaaaat acagaaatat atcaaaaaat agatacaatc
     3601 atacttcata tgcccgatta tataaaagat tttgttcaag atcgtgagga taaagatcaa
     3661 tcacctcgaa ctactttaga atatctaaaa aattataagc tcttttatga atggcttctg
     3721 agtgagtcta tcgttcccga tacttcaatc acctcgataa gacagttaac tgcctatgat
     3781 ctaaacttgt acaaatctca tttgaaacgt cgcacaaagg aaaatgtaaa aaaagagaca
     3841 acaaaaacta agctcaaaga taataataac ttaggtctat ctacttctac tatcaataga
     3901 aatatcacag cattaaaggt tctatttaaa tatctttcga aaagttccaa taatccttta
     3961 ggaaaaccat acttagaaaa taatcctatg gatcaagtag caactatcac agataaaact
     4021 acgttagctg cccgtgcaaa cgcaatcgag aaaaaattat ttctagacga agatacacaa
     4081 aattatctag attatattgc caatgaatat aaaaaaactt tgagcaaacg agctttgatc
     4141 tattatcaac gagatgtaga aagagacctg gcgatcaatg cattgatttt aggatctgga
     4201 ttaagactct ccgaggttgt aaatattaat ttagaggacc tatctttaga aaagaataat
     4261 gtggtagtaa ctagaaaagg aaataagaga gacgcagtaa atatagcagc atttgcaatg
     4321 gaatatttag ctaattatct agctattcgg aaagaacgat acaaagtaac agaaaacgaa
     4381 aaagctttat ttctagcaat ttatcaagga gaagccaagc gtatatccgg tattgcaatc
     4441 gaacggatgg tagcaaaata ttcaaaagga ttcagagtcc aagtcagtcc acataaatta
     4501 cgtcatactt tggctactag actctatcaa cagacaaatt cattggtatt aactgcccaa
     4561 caattgggac atacaagtac aaatacaaca actttatata ctcatataga caatgcagct
     4621 acaattgatg ctttgaacgc tttgtaaatg tagtaaaaaa tagtataata atgaagcctg
     4681 tctctaaaat tagataaaag cccaacttta aaggcaagct tcattatcat tttta
//
LOCUS       DAIGWC010000124         4590 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.127, whole genome shotgun sequence.
ACCESSION   DAIGWC010000124 DAIGWC010000000
VERSION     DAIGWC010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.127"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            186..2855
                     /locus_tag="NOB74_002689"
     CDS             186..2855
                     /locus_tag="NOB74_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HCI1221815.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="NOB74_002690"
     CDS             complement(2946..3566)
                     /locus_tag="NOB74_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1221816.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="NOB74_002691"
     CDS             3680..4219
                     /locus_tag="NOB74_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221817.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="NOB74_002692"
     CDS             4216..4554
                     /locus_tag="NOB74_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HCI1221818.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1420 a          790 c          860 g         1520 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgacatt
//
LOCUS       DAIGWC010000125         4482 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.128, whole genome shotgun sequence.
ACCESSION   DAIGWC010000125 DAIGWC010000000
VERSION     DAIGWC010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.128"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(24..959)
                     /gene="murB"
                     /locus_tag="NOB74_002693"
     CDS             complement(24..959)
                     /gene="murB"
                     /locus_tag="NOB74_002693"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HCI1221819.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1032..1952)
                     /locus_tag="NOB74_002694"
     CDS             complement(1032..1952)
                     /locus_tag="NOB74_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1221820.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2065..2817
                     /gene="xth"
                     /locus_tag="NOB74_002695"
     CDS             2065..2817
                     /gene="xth"
                     /locus_tag="NOB74_002695"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HCI1221821.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3681..4214
                     /locus_tag="NOB74_002696"
     CDS             3681..4214
                     /locus_tag="NOB74_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HCI1221822.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT         1322 a          878 c          795 g         1487 t
ORIGIN      
        1 cttattttaa gttccattac ttattaattg gctaaacttc tgcttgtttc tgatattgct
       61 tgtttttctc caatgatccg cacttctgtt tctaaagaca catcaaattt ttctttgatt
      121 acttcttgga tgtgcgcaat caattcaata taatctgtcg ctgtcgcatg atcgatattg
      181 acgatgaatc cagcatgttt ttcagagact tgtgcaccgc cccatttcag gccttgcaat
      241 cctgcttgtt ggatcagctg acctgtatag tgtcctactg ggcgcttaaa gacacttccg
      301 catgaagggt attctaatgg ctgttttgat tgacgcaatt cggtcaactc atccattctt
      361 gctttgattg cttcataatc ccctgtttgc aaactgaatc gagcttccaa tacgatagca
      421 cgtaattctt ggactttact gtgacgataa gaaaatacca tttcgtcttt tgtcaaagtt
      481 ttcaatgttc catcttcaag caaaagatcc acttcagcaa aaacatcttt gatctctccg
      541 ccatacgcac ctgcattcat ataaaccgct ccaccgacac ttcccgggat gccgcaagca
      601 aattcaaatc cagtcaatga ttctgccaaa gctgcataag tcgtatcaat cagtgaggca
      661 cctgcttccg caatgaccat cgttcctttg acatgaatct gtttcatttc agtcagcatg
      721 atgactacac cgcgaatccc gccatcttga acgatcagat tgcttgcatt tcctaatacc
      781 atccaaggta tatcatggat tcggcaataa tcgatgattt gctttacttc ttcttgtttt
      841 ttcgggaatg caaggacatc agctggtcca cctgttttcg taaacgtata gttcatcaat
      901 ggttcatcaa acaatatagt aatcgtggct aagctttcaa ctatttcttc tttattcact
      961 gaggattttc ctttcttttc tcaaacgtcc tcattattct atcacgctta atacaatctt
     1021 gccagtcttg ttcaaagttg atgacggtag tgatctttaa gcacttcctc acataattca
     1081 tgacttctta caacttcttt ttgtttaagc aattctgttt ccgatttacc taaacggatc
     1141 tgagaaaaga aggcctctac cattggctca aacccgcgtt tgactagcgt gtttgtccag
     1201 tcgccaaatt ctttcacttt ttttccatca gcatcttgaa tgacaagctg ggtcagatcg
     1261 tttacttcat aagtaccatt tttacttgtt acttgatatt tttctatatt agcgccactt
     1321 gctaaatcca tcgttaaaat agccgtttga ttttgtgttt ctaattgtaa aatggcatat
     1381 tccaaaaatt cctttgtttc tcttatctgg tattttgttc tcaaaatggg ttcatctaat
     1441 aaatacacag ctgtatcaat aagatgtaaa aacaaatcat aaaggacgaa ctctgtcgtt
     1501 tcttttgccg ctattcgatt tttttgcagg tggatcaacc gcttatctgg gatacgtttc
     1561 aattcttcta ccataggagc aaagcgccgg ttgaaaccga tcatcaaaat tatttggttc
     1621 ttatcagcta attcttgcaa ttcacgaact tcatttagat ggacactcag tggtttgtca
     1681 atataaacat ggataccatt ttctagacat tttttggcta attcataatg tacttttgtt
     1741 gctgcgtgga tcatacatgc ttcgattttt tcttctaaaa gctcatcgat cgtttcatat
     1801 agatgttgga acccgtactc tttttgaatt ctttcttttg tttctttatt tcttgttgca
     1861 aaataaaaat caagtgttcc ttgttttttc gcataagttg gtaaatatgc tttttctgcg
     1921 atattcccta caccgattac accaatcttc atctactttc ctcctggatc atttagttac
     1981 tttcatctta caccattttt tactaaaatg aggtacaata gtatcgcaaa ggtaaggaaa
     2041 ttaattcgaa ggagtgtgct tttattgaaa tttatctctt ggaacgtaaa cgggcttcgt
     2101 gccatcgtaa ataaaaattt tttagaagtt tttcatgagt tagacgccga ttttttctgt
     2161 ctgcaggaaa cgaaactcca agcaggacaa attgatttag atcttccagg ttattatcaa
     2221 tattggaatt acgcggaacg aaaaggctat tccggcacag cgatttttgc taaaaaacca
     2281 gcattgaatg ccacttacgg aatgggtatc gatatccatg atacagaagg ccgtctgatt
     2341 actttggaat attccgattt ctttcttgta acctgttaca cgccaaattc tcaaagcgaa
     2401 ttaaaacgtt tagattaccg attagaatgg gaagaagcct tttataatta tttggaaaat
     2461 ctaaaaaaac aaaaaccagt catcgtgtgt ggggatctaa atgtcgctca tcaaaagatt
     2521 gatttgaaaa actggaaaac gaatcaaaaa aatgctggat tcactccaga agaaagagcg
     2581 gctctttctc gactgttgga taacgggttt atcgatacat tccgttattt ttatccaacc
     2641 caggaaggtg tctactcttg gtggaactac cgattcaatt caaggaaaaa caatgctggt
     2701 tggcggatcg attacttttt gacgagcaaa gatttagagc caggactagc tgatgcaaag
     2761 atccatacgg acattatggg cagtgatcat tgtccagtag aattagattt gaaataaaga
     2821 ggttgtgaaa aagtcgttta gtttcgagta ttaagaaaaa ttttgtgaaa atggctttcc
     2881 acattttgca taaatttggc ataataccga gaaactggct tttgaacact gtttatcgag
     2941 agattgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagttcct
     3001 catatttttc gtttggttgg gcttattacc gcagatacaa gcttttgaac accgtttatt
     3061 aagaggttgt gaaaaagctg cactgcatca agtaataaga acagccaaac aaaaatagtt
     3121 cctcatattt ttcgtttggt tgggcttatt accgcagatg caagcttttg aacaccgttt
     3181 attaagaggt tgtgaaaaag ctgcactgca tcaagtaata agaacagcca aacaaaaata
     3241 gttcctcata tttttcgttt ggttggactt attaccgcag atgcaagctt ttgaacaccg
     3301 tttattgaga agttgtgaaa tcagcgtcct gacctgagta ttagagaaac aaatggcaaa
     3361 atagttcctc atattttgct attttttgag ctaataccga gggtcagctg attgaacacc
     3421 gtttagtgga gaagttgtga aaaagtcgcc tactttcgag tcgtaagaaa tttttttgaa
     3481 aatggttcct cacaactttg cataaatttg acttaatacc gagaagtcat gatccccatc
     3541 taactccaaa tcacaaggaa tgagttcaaa aactagcttt tctcaacaaa tattacataa
     3601 aaaattctat gttttttgtt aaatttattt gcttttttca aaagtatgtt acagtaattt
     3661 cccaaggagg ttttacagaa atgaattttg ttgccatgga ttttgaaact gccaatcatc
     3721 agccttatag tgcttgttct cttgcgctag tcatggtaaa aaatagccag atcgttgatg
     3781 aattctatac attgatacag cctgagactc cttttttctg gcgaaatgtc caaattcacg
     3841 gaatccatca agaagacgta cgcaatgcgc cgaaattccc agaagtctgg caaactatcc
     3901 aaccatattt tcaaaaaaat cgtttagtcg ttgcacataa tgctgctttt gatacaaagg
     3961 tcttagcggg atgcttagat tattatcatc ttgaacagcc taattatctt tctttatgta
     4021 cagtgaaaag tagccgtcgc ctgtttcctg aatttccaaa tcatcgattg aacactgtgt
     4081 gcgaaaattt gaacatccaa ttagatcatc accatgatgc attggaagat agtcgtgcat
     4141 gtgcggaaat cctgctttat caagaaaaaa aattcgggac agatccattg aaaaaacttg
     4201 tgactataaa gtaaaagaat acttatgaaa cacacaaaga ggtcgtgagc ctgccgtttc
     4261 actccgagtc acaaggagca atttcaaaaa atagcttctc atgtttatta aatattgtga
     4321 ctggtgaccg aggagctggc aggagaacac cgtttattgg agaggttgtg aaaaagctgt
     4381 tctgcatcaa gtaataagaa cagccaaaca aaaatagctt ctcatatttt tcatttggtt
     4441 ggacttatta ccgcagatgc aagcttttgg acaccgttta cc
//
LOCUS       DAIGWC010000126         4455 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.129, whole genome shotgun sequence.
ACCESSION   DAIGWC010000126 DAIGWC010000000
VERSION     DAIGWC010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.129"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(458..883)
                     /locus_tag="NOB74_002697"
     CDS             complement(458..883)
                     /locus_tag="NOB74_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221823.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1257..2228
                     /locus_tag="NOB74_002698"
     CDS             1257..2228
                     /locus_tag="NOB74_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1221824.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2260..3657
                     /locus_tag="NOB74_002699"
     CDS             2260..3657
                     /locus_tag="NOB74_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1221825.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3816..4439
                     /locus_tag="NOB74_002700"
     CDS             3816..4439
                     /locus_tag="NOB74_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221826.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT         1558 a          715 c          909 g         1273 t
ORIGIN      
        1 attactacgt gatgtagaat aagcctttct atcgtttggt tattttatat tcaaatattt
       61 gaaataaata aatctttact ctttgatttg taaactgaaa tgatccactg tttgttttac
      121 tgatgaagct tgatcaaagg aagaagctga gtttgaagtt cataaaaatc agccatagtg
      181 agttttgctt ggatttgttt atcttcttct actttttaca taattttgaa caggataaga
      241 ttcaaatgtt ttaaatgaat ctttgactag tttgtgacag ttgtcgcata tgctcaagct
      301 tccttggtca ttaaattctg tatggatatt tttgttgtta ttacatgtac aataatcagg
      361 actatcgatc atccatttcg tctcctttac aatcatcttg cttctttact atagcagaaa
      421 agaaggggag aaacaaaaga agatccaaca gacggcacta tagactgtag atgttgccat
      481 cctcatcctt caaacggtaa ttaccgattt ttgtaaatat gactgttgtt tcttttttat
      541 tttcttttcc tgaaataata tattcgtcat ctttggtagt gatcttgata tctgtcagca
      601 ctgttttttc ttcagatgat tcagaagaat cagttccttg tgtctgatac gtgcgtgtcc
      661 attccatttt tttatctgta aatgtcaact gtcccgcgga taaatccata tctttacgta
      721 cttttagcgt atatacactg ttggtggtat ctgctttttc cgcttttaag acagaagaat
      781 cggttgtttc gtccgaggat tggtcagagc cgccaaacaa atcacagcca gtcaatgtca
      841 aaagtcccgc agacaaaata aatagtacga ttaatttctt caaaatactt cccccatttg
      901 ataggataaa gaaattatac cattggaatg taaaacttca aacggatgga agagaaaaac
      961 gcacaaaaca cccacaaata gagtaaattt tagaataaaa ttttaaaaag gcaaaaaatc
     1021 cgccactttc agaaagcgtt ttaaaaaagt gttgcaatct tttaaaaaaa tgctatatta
     1081 aaaatgaacc ggttcaaata cttgtttaag tataattaat agtgagagga agttgctcta
     1141 ctgaagactt tagttatatg gatattgatg acaagcaaca ctatgcaaag aatgcggtca
     1201 tcataatcga acaacaagaa agagaaatca aatgtaactg gcaggagtga gaatgtatgg
     1261 catcgatccg tgatgtggct aagatggctg gtgtttcagt gggaacagtt tcccgttact
     1321 tgaatggtca gcaactgaag gaaaagaaca tgaaaaaaat agcagaagcg atttcagcgt
     1381 tggactataa agaaaacatc attgctaaag ggttgaagaa taatcgaagc ttctctattg
     1441 gacttttgat aaacgggatt tccagccgtt ttgggtcgga agttgtctca gggatcgaaa
     1501 gagtagctga agaaaatggg tatagcttat tattaagcgg gtttgccgat cagccagaaa
     1561 aaattgaaca aaaaattgaa tacctgatga agcatgtgat cgatgggctg attgtcttct
     1621 tatccgaaga agagtggtct ggatttgaaa tgctcacaaa aatgagtatt ccagttatcg
     1681 cattgaattg tccagaagga ccagcaggta ttgatacaat attagtgaat gatcgagaaa
     1741 gtgtagcaaa agtgatcgct catcatggtg aacaaggaca taaaaaaatc ggatttattg
     1801 ctgccactca aacagactac gtagcaagag aacgtttagc aggagccaaa gaagcggtcc
     1861 aaaatgatcc atcgatccaa ttagaggtct ttacaggaga ctattctaga aaaagcggct
     1921 attacggggc aaaagcatta ttagaaaaag gggcaactgc tatttttgtc agcaattaca
     1981 atatgtcgat tggtgccatc gaatgtttca atcaagaagg tgtcagaatc gggaaggata
     2041 ttgcgttcag tcactatgat tatttagata aaaacgatct gagtatcctt ccgaaaatca
     2101 cgatcacgcc accaacagat aaaatcgggg aacgagcagc agaacagctg ttaaaacgaa
     2161 tcaaaaaaga agaggaagaa aatgaaaaag tgattgtgat ggaaaatatc atacatggaa
     2221 tcaactaaaa cgaactaaaa aagaaaaaga ggtgctttga tgaaaaaata tcaatttcca
     2281 gcaaattttt ggtggggttc tgcagcaagt ggcccacaaa cagaaggaag gatttcaggc
     2341 gatggaaaag gagagaacat ttttgattat tggtacaaaa aagaaccgca aaagttcttt
     2401 gatcaagtag gacctgaaaa aacctcgcaa gtttatacga agtatcaaga ggatgtacag
     2461 ttgatgaaac agactgggca taattcattt cgaacatcta tccaatggag ccgtttgata
     2521 cctgatgaat ctggaacaat caacgaagaa gccgttcgtt tctatcatcg ttattttgat
     2581 gagttgattg aaaacggtat cgaacccttt gtgaatctgt atcatttcga tatgccgatg
     2641 tatctgcaag aaaaaggcgg atggttgaac cgagaaacgg ttgaagccta tgaaaaatat
     2701 gccaaaagtt gttttgaatt gtttggttcg aaagtaaaaa aatggtttac tcataatgaa
     2761 ccaatcgttc cagtcgaagc aggttattta tatcgatggc attatccaga agagtcagat
     2821 atgaaaaaag cgatccaagt tggctatcat gaagcgttgg cttcagcgtt agccatcaaa
     2881 tcttaccatg aaatggagca aggtggtgtt attggtatca tcttgaatct gacaccaagc
     2941 tatccaagag acgaatcaaa ccctgaagat gttaaagcag cgcaaatagc agatgcgttc
     3001 ttcaatcgtt cattccttga tccagctgta aaaggcgagt ttccaagtga attgattgag
     3061 atagtaaaag aacttgatct catgcctgtg atccatgcag aggatttgac ggttatcaaa
     3121 gaaaatacag tagatctttt aggtatcaat tattaccagc cacgccgggt aaaagcaaaa
     3181 gaaacaccaa tcgatactaa aaacggtcca atgcctgagg attatttcga caattatgaa
     3241 atgcctggtc gtaaaatgaa tccttatcgc ggatgggaga tctatgaaca aggaatctat
     3301 gatattttga tcaatgtacg agatcattat ggaaatatcg actgctttat ttctgaaaac
     3361 ggtatgggtg tagaaaacga agcacgattt atcaaagaag atggcatgat ccacgatgat
     3421 tatcggatcg aatttgtcca atctcatctg aaatatgtcc atcaagccat tcaagaaggt
     3481 gccaattgtt taggctatca tatgtggaca tgtatggata actggtcgtg gaccaatgca
     3541 tataagaatc gatatggctt tatttcagta gacttagcac aagatggaaa aagaacaatc
     3601 aaaaaatcgg gtcattggtt caaagacgta tcagataaaa acggatttga ggcttaagaa
     3661 agaatagttg agagcaaatg cgtgaaattc tccattctta ccattttgtg aaaaagaagt
     3721 tcaattattt acgatctttt tcaacttttt tgtctttcta tttcattttt tgtatataat
     3781 agaatagtca aaattaaata ggagtggagg aaagcatgag gaaaaaaaga ccgtttcttc
     3841 tcttttggtt attcggtttt ttcttactgc ttattttatc cgcagcattt tcaggaaaaa
     3901 tgacagcaga tcttgctcag aaagaaacag aaaaaatcgt agcaagcaaa gaatcagtag
     3961 ataatttcaa aaaagaattc tcaacttatt ggtgggcgga gtataaaata actgccaatt
     4021 acgaaaaagg cgaattggac atttatttgc caaaaggaaa agaagaaaat caatttatta
     4081 atatcgatga cgtacttagt gcgatttctc tcagacaata tcaatttaaa gacaagcatt
     4141 tgaccgtttt gcttttgact catgatggcg acaaagtagc ccgtttgaaa aatggaaaag
     4201 tgatcaccgc ttattctgaa aaagtagaca aaaaagtggt cgccgatcgt ttagcggaat
     4261 ggaaaaagac aaatgaacaa gtcaagaaaa caactgtctc ttctcaaaaa aacgagtcga
     4321 caggaacaag tccttcagat tctggcagtg gacaaacgat aacgggaagt gaagaaaatc
     4381 aagcctcaat tattacgaat gagtcatcac aaggacaata tcaatcctat ggacaatgaa
     4441 aaacagaggt tgtga
//
LOCUS       DAIGWC010000127         4433 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.130, whole genome shotgun sequence.
ACCESSION   DAIGWC010000127 DAIGWC010000000
VERSION     DAIGWC010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.130"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(543..2048)
                     /locus_tag="NOB74_002701"
     CDS             complement(543..2048)
                     /locus_tag="NOB74_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1221827.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="NOB74_002702"
     CDS             complement(2045..2731)
                     /locus_tag="NOB74_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1221828.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="NOB74_002703"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="NOB74_002703"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HCI1221829.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1546 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat att
//
LOCUS       DAIGWC010000128         4067 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.131, whole genome shotgun sequence.
ACCESSION   DAIGWC010000128 DAIGWC010000000
VERSION     DAIGWC010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.131"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            86..1435
                     /locus_tag="NOB74_002704"
     CDS             86..1435
                     /locus_tag="NOB74_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1221830.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="NOB74_002705"
     CDS             complement(1563..2153)
                     /locus_tag="NOB74_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCI1221831.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="NOB74_002706"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="NOB74_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCI1221832.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1173 a          744 c          789 g         1361 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagtttt cgcaaaa
//
LOCUS       DAIGWC010000129         4035 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.132, whole genome shotgun sequence.
ACCESSION   DAIGWC010000129 DAIGWC010000000
VERSION     DAIGWC010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.132"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(243..392)
                     /locus_tag="NOB74_002707"
     CDS             complement(243..392)
                     /locus_tag="NOB74_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221833.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            854..1066
                     /locus_tag="NOB74_002708"
     CDS             854..1066
                     /locus_tag="NOB74_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221834.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1344..3143)
                     /locus_tag="NOB74_002709"
     CDS             complement(1344..3143)
                     /locus_tag="NOB74_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCI1221835.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3267..3863)
                     /locus_tag="NOB74_002710"
     CDS             complement(3267..3863)
                     /locus_tag="NOB74_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI1221836.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1449 a          711 c          689 g         1186 t
ORIGIN      
        1 tatattaaat attatacaga taataacgga atattatcat cgaaacagct aacaaaattg
       61 tcataaaaaa cgagatggtt gatattagaa cttgtgtttt tgtttaggtc tagagataaa
      121 gagagacaat ttccaaatat atgtaatgaa tacaaaaaga cgtttgtcgc ggattaccgt
      181 tacaaacgtc ttttattgat tttccgagat ctcatcagtc gccatttgga atggttcact
      241 ccttatctag attcgtttaa tgctcggact gcttgttcga ttgtaatacc aaacgcaacg
      301 ttattttcgt tttgtgcatc aatcgccata aaacggttag aagttgtatc aaaagctacg
      361 cggtattgca tatttgtttt tgtaaacgtc ataaaattca tctcctttgt aatgtaattt
      421 agttcttgaa agtttccttt aaactttcga acttatacca agtttagcat cgtacgtttt
      481 ttgatgcaat taaaaagcat ttatcatttt ccttatttat tttttcttaa atggtttagc
      541 tattttcttt taatccgata agtagcccaa tcatcaaggt tacaaatact attgcttgaa
      601 tataaatcat atgctcacct ctttataaat aacttagcaa tataaagaaa aaaacgcacg
      661 aacaacatag gaatataaac aaacgttttt gtcacaacgt ctaagatcgt gttaaaaaat
      721 agttatctaa aaagcagaaa gatactcaaa ataaaaaata aaaaaatgga taaaaacgtt
      781 ttcaaataca aggtaatttg ttattataaa ataaagaaaa aacaaaataa aaataaagaa
      841 aagagggaat gaaatggtaa aagcagaagt aggaagatct tatatatgca aaccgatcgg
      901 agtatctcat gaactaatcg gctgtattga acgtacatat atcaacacgg ctgtcgtgta
      961 tgttgaaagt tatgaccaac gagactatca acttatcaat gaaagcaagt atcgcatgct
     1021 cgtaaaattc tgtgatatta gcgcacctgc tgaattggtt tcttaaacag tatttttgag
     1081 aattcgcaag aactccctta taatataaat aaagacagaa gggagcgaga agatatgcca
     1141 aaaagaaaaa gttcagggaa aatgggaatt attcttgcag tgatctctgc aattcctgct
     1201 attttagcta ttgttcgtgc gatgaaggaa tcaagagaaa gttaagcaca cattatgagc
     1261 gtcaaacaaa aaacgcatat acctgcggtg gcaggttatg cgttttttgt tgtataaaga
     1321 cttttttcat taacgatttt tgattagccg actcccaaaa caaaatttag cagtttatct
     1381 gaataagtga tttcttcatc tgtttgtttc acactttcat ttagtagtcc catctcatcg
     1441 gttatgatac catccacacc ataaaacatc atgcgactca tagcatctga atcgttgatt
     1501 gtccatacat atacttcttt tccgtcttgg tgggcagaat taatgaagtt acggttgatc
     1561 gtactatatt ccattgtcag aaaatcagca ggcgtcacag ggggcccaac aatattgaaa
     1621 ggtaagatgt agcccacata aaagtttggt tctgcttctt ttaaatctga aacggtttgg
     1681 tacgtcaaac tttgcaaaat atgatggttc tctaagataa ctttgcggta tttatggaca
     1741 aatcgttcga caaggtcatc cgaatctttt ttagaggtct tgatctcaat aagtaatttt
     1801 tggtttagct tatgtgcttt ttccaaataa gaatcaaaag aacaaacagg ggcttgcact
     1861 ccgttttcag taactgtaag atttgtcaat tctttcaatg taagatcctg tggtgttcca
     1921 tttacccctg ttaagtgacg aagatttgca tcatgcatca ctacgaaatg accatctttt
     1981 gtttcctgaa catccatctc tacataatca ggatgatagt ctctgcttgt tttttcaagt
     2041 gcttctaaag tattttgcgc cccattttgg gtactcacac ctctgtgaga gacagtcact
     2101 ggttttgtct gaacagctga agtcagataa tccatattgt aaagacagac gccaataccg
     2161 aaaaaaactg caaaaagagt caaaccagtg tttttcagcg cagagaaacg caagttgggg
     2221 gcttgtggga taaaccactt agggatctca ggcaagaagc cttcgtcatc catgaaatca
     2281 acaatgatat aaaaaatccc tacggtagac atcacgatat tgaataataa aatcccttgt
     2341 aaaagcgtca tagcaaacac agcgctgatc aatgcatagt ctgggaaaaa ttgttcaacc
     2401 atactttgtg ccaaaataac aacgatatat cctaaagaag aaaggagtaa aatcgtaccg
     2461 ccaatcacaa taaattggcc cgtgatggcc aaaagacgcg atttggtcaa tgaccagctt
     2521 tcccgaatgg ctgctcgaaa aggacgatct cgtagaatca tttccggtaa agcaaaaatc
     2581 agtcgaatcc caatatagcc aaggaaaata taaacgagta aaaaggaact gacgatgatc
     2641 caacgattag caaaaataaa atccataatg aaagcgggga tttttatttt tgacagtaga
     2701 tcagaattaa aacttaatcc gctgatcggt agaatcaata aaaaataagc aaggaaaaac
     2761 aaaaaagtaa tgggtctcac tttcttcagc tgaagtatcg tcaagtgtaa gagttgcttc
     2821 aaagagattg gttctttctt tttaataaaa aaaacactca tcaaaagaaa agtaaattcg
     2881 aaataaacta acagtaaaat cgtcatcaaa actacgatta acgagagtag aaccccagga
     2941 tgttgagaaa aaattgaagg aatattgtca taagacaaat agtcaattgc ccctcggtgt
     3001 aaaataaaac gggtcgtact gctcaataag ggtaaacaaa taaataaaat aaagccatgc
     3061 atcagcaaga catcacggaa ataagcttgt gttcctttta aaaagtccca agcattacct
     3121 aagctacgtt tcaaataatt catcctatca cctgctcttc acattgtagc gcaaatctaa
     3181 tgaaaaagga aagggtgcag tgtgttttgc agaccctttc ccagatttaa cattgtcaat
     3241 caatgactaa ttttacaaaa taaatattat ccaagaagac cacttagata ttgacctcca
     3301 taaatcaagg ccatactata taagaaaatc gacagtggtt tagcaatcaa aatgattagt
     3361 gtatatcgtt tcactgacat gtttgtcaat ccagccatca aacataacgc atcgtcagga
     3421 gcaactggaa gaaaaatagc tagagcaaac agcttctcaa aacggttttg attatccagc
     3481 cagccaatat atttgttata tgtcttatcg ctaatcatgg aaagtatgaa tggctttcca
     3541 taacgacgcc ctagcagaaa aatgataatc gaaccaatgc agattccaat atagttatag
     3601 ataaatccag cataagggcc aaatatcagg acaccagctg cagtactgat ccctccagga
     3661 atgattggaa taactacttg caggatttgg atgaagacaa aaataatcgg tcctaaaatg
     3721 atggaatcac ctactaatcc tcttaacgca ttcaaatctt tgaaaacacc taaattaata
     3781 aaataaatcg tcagcgcgat tgataggcct aatccgataa tggatatgaa atttatcagt
     3841 tttcgagagg cagcaatatt cattattcat caactcctta gaggttcttt gttaactata
     3901 ctttactaga aaagcaacta actgcgccat tttttgatat gacagaaaac aaacaatttt
     3961 gtaagttcat cataagtata aaagattgat ctcaaaaaaa catccaacta aagacttatt
     4021 taataacttg ttttt
//
LOCUS       DAIGWC010000130         3980 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.133, whole genome shotgun sequence.
ACCESSION   DAIGWC010000130 DAIGWC010000000
VERSION     DAIGWC010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.133"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(629..1186)
                     /locus_tag="NOB74_002711"
     CDS             complement(629..1186)
                     /locus_tag="NOB74_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221837.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1365..1976)
                     /locus_tag="NOB74_002712"
     CDS             complement(1365..1976)
                     /locus_tag="NOB74_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221838.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2089..2346)
                     /locus_tag="NOB74_002713"
     CDS             complement(2089..2346)
                     /locus_tag="NOB74_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221839.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2943..3221)
                     /locus_tag="NOB74_002714"
     CDS             complement(2943..3221)
                     /locus_tag="NOB74_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221840.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3255..3506)
                     /locus_tag="NOB74_002715"
     CDS             complement(3255..3506)
                     /locus_tag="NOB74_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221841.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1208 a          816 c          529 g         1427 t
ORIGIN      
        1 aagcagaagc aactccttct tatttcttgg agttaaacgc ttctgtccca gcctccttat
       61 tccgaataaa tggtgtccaa aagcttgcat ctgccagatt atctcatttc ttatgacaag
      121 ctaagcaaat tatctccacc aaataattta ttcatatttt tgacttgcgc atactaacta
      181 attcttaaat tttcatacaa aatttctcaa tttcccttaa cgagtaatat ttatgtacgg
      241 tgattctcac tagtatccca atcacttttt aagttatccc gatttcaatt ctacttcaaa
      301 aatagttgct tttatgtatg ctgttagttg attagatggt catttgttga gctaggtcgt
      361 ttattttaaa caagttgttt ctttagctta tacctatctc gtctaccaaa cgcaagatgg
      421 caaacacaaa tgcatacgca tctgtatttg ccactttgat tcgtataaag ctaacaacta
      481 ttaactcctc tcagctaata gttgctctct tttttattca gattcatttt tgctgatcac
      541 agcctagtat ttcaatggtt ttgaacacta aaccaaattg ttccattaca acattcactg
      601 gctgatgaaa tggattagta gatttcgatt attcaaagcg attttctatt ggtggatcgt
      661 gttcccaact aataagacgg attccaaacc tatcgtacag atcttctaaa ccacttataa
      721 attttgcacc tatttcaggt gttttattgc gtggatattc tattgttacg ccattaaatg
      781 gataccaatt aggattaggc tctctttttt tctgtacatc tcccatagaa tagttagcac
      841 tttctgggac ataatatatt cttcgaccat cctctaattc atctaataag atatttcgtg
      901 atcgtctatc acttgctaaa tgtagacgcc acgtgcgata ccatgccatg ctacctgcat
      961 ctgcagaaaa tccatcaaat aatgcaacaa ttgtatcttc tatcacaatc ctttccccat
     1021 ctacttcata ttctaatcta aaatcaaact cccctcgggt aatttctggt cttggtggct
     1081 taggacccaa tattattcta cttaaaaccg cattcgttcc cagatgaaac acagctataa
     1141 caacaataat gattaatatt ttgtttctat ttgataaatt tctcattatt cgcacatcac
     1201 ctctacattc tcacatatta gttcgtaata ctcctttaat atcaaaatat ctactggtcg
     1261 taataatatt cgctatgaat tcctactact cgtataagaa aggccaaatc atcagctttt
     1321 acttgctgat gatttggctt gtttctattt atcgtaattg ttttctaatc accaaaattg
     1381 ttaacaatcg gttcagatat ttcccagttg attaaggtaa ttccgtattg tgtcaaaact
     1441 tcttgcgctt ctccgaaatt aagtacagtt cttatgtatc cactttctcc taatataaag
     1501 tctacctctc ttttaaaacc ttcctcgaga tttctaaggg ctatatgtgg ttttaatgac
     1561 attgattgta cattttcccc catataatat tgcgcacttc ctcgactaaa atagattcct
     1621 agatcgtccc caaaaggtag atcttctcta ccactagcta atctacttct ccatcttcgt
     1681 tctcttttca tagaacctgc gctgaactca cacccgttaa actcagctat gacagtatct
     1741 tcaattatgt taatctgtcc atctagttcg tattcaatcc taaatggaaa ttctccatag
     1801 gtgatttccg gttcgggtat tttaggtgag attaatgcaa agaaaggaaa tattaagctt
     1861 ggcaacatca aaaaaactcc tcctatgatc acaattcccg atgtaatcca aaatataatt
     1921 tgtacaattc tcattgatcc attgtattcc attttattcc ccctattact attcatatcc
     1981 gcctatctat atcgatcttc caatgcagag ataattgctt ccataccttg attttttact
     2041 gagttaccta tgcgagatat cattctccac taaggtgcat catattgtct atctaacatg
     2101 attaattctc caataggtgt atactcctcc aaaaacaaca tttaatgcat ctccctcgac
     2161 aacataagct accatgtttg ctgtatatgt gtttgagtct aattcataag cagataaatt
     2221 tactgtcgct ggattaaata taatcgcatt cgtatttata gctactgaat ttgctgcttc
     2281 agcaccacct tttgaatgtc cgatcattgt gatttcaata gtaggattta cgtggacagc
     2341 cctcaccgtt taccctgacc attatagaaa tcgcttactt ttttgaacta cgcaacaaag
     2401 gatacaatgc tcctaacttc actgtctcca tttttgtcca ctaaggaata taaaaaatag
     2461 gcattaattc atttaattcg gtcacaacac gttacctttt aaatcattat actgtatctc
     2521 atacattatt atcaataaac tattataaaa atgcaaaaaa tgctttatca atctattttg
     2581 taattggtca taatatcatt gaaatcatac cctgtatcga tttttcctat gaatctcgtc
     2641 tatttgtgat tgacgaaaaa gaggcaagac agacactgga atggtaattt tacccactat
     2701 tttgctccaa ctatttgtaa tcgtacccac ttttgaaata ccgagatgat cattttaatt
     2761 gatatgctga ttcccaagca aaaccccaag aaattaaatg ctctatcgca tctagcttct
     2821 tgggttttgc ttatataaat tccaacattt aaatttttta tgctgttcgg tctcagaaat
     2881 gccgtttttg cttatatcac aatatcaaga tgtcaaatta ttcgtgttgc cgatgacttt
     2941 gattaatttt tttcaaattg tttattaaga ctaatgctgt ctttttgcag ataccaatgt
     3001 tcgaactttt taacattatc atatgatcct gcaagtttta acttcttacc attagatgtt
     3061 atcaaagtta taattaacct tgcctttttc ccattaggat cttttatttt atgaattttc
     3121 tgcaggtaat ctctcctaat ggcagctatt tttacctcat cagtgctgat aaaccattga
     3181 tcatccacat acatactgcc tgttatgttg tgtttttcca tttcttccga gaacgaaaag
     3241 tttaaggctc gttcttactt ccaaagttga atgagtccat ggattggact tagtgtgaga
     3301 attgagaaca acaataagaa tccatatcct cccgcaaaca tccctaaggc tatactgtct
     3361 ctccatccat aagtaggatt agaagagaaa agagtcaccg tttgtaataa tatgaaaagg
     3421 aataatccag cacaaacacc aaagataaca actccaaaca ttgaattttt atacaatgac
     3481 catttattta taggcttttc tttcatttta cttcccccta ctgttctgtt cacacggaat
     3541 gaattcaaag ttcataagcc ctcctctttg aacatatgaa tacgacttgc taactatact
     3601 ttaaaaaagc ttgttttaag cggttatagg cgagttgtaa tctctattca tctcattagc
     3661 aaataacttg ccgaaaagtc tactgaaatt aaagcagata gtggaagaat tatttagcca
     3721 ggatagacac tatttgtgaa acacatgtct ttacttttga aattctatga tgaaaagcct
     3781 tggaatacag tagctcttaa ttggtaatac tttttccatt ataaataacc tcttttcatt
     3841 ttatatttat cccctctaaa aataatatct aatctaatat tttaaactta tatttccctc
     3901 gctgtgctaa tagagcatta ctaaataaat agaaactaga aaaaagcatt acgcctgcca
     3961 gaataaacca attatttgta
//
LOCUS       DAIGWC010000131         3354 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.135, whole genome shotgun sequence.
ACCESSION   DAIGWC010000131 DAIGWC010000000
VERSION     DAIGWC010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.135"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            212..478
                     /locus_tag="NOB74_002716"
     CDS             212..478
                     /locus_tag="NOB74_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HCI1221842.1"
                     /translation="MDSLPVELQALCWNLIDQNVQKQFPLDYLQIFEFSTEKGNQKLV
                     HRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY"
     gene            505..804
                     /locus_tag="NOB74_002717"
     CDS             505..804
                     /locus_tag="NOB74_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HCI1221843.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            978..1529
                     /locus_tag="NOB74_002718"
     CDS             978..1529
                     /locus_tag="NOB74_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HCI1221844.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            1675..1968
                     /locus_tag="NOB74_002719"
     CDS             1675..1968
                     /locus_tag="NOB74_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221845.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            1961..2257
                     /locus_tag="NOB74_002720"
     CDS             1961..2257
                     /locus_tag="NOB74_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221846.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            2332..3330
                     /locus_tag="NOB74_002721"
     CDS             2332..3330
                     /locus_tag="NOB74_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HCI1221847.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
BASE COUNT         1262 a          459 c          664 g          969 t
ORIGIN      
        1 agatttagaa aaacttacta aacaaagaga tatgaaaaac tttaataatt gtgtagtttt
       61 gataattata actgaattaa ctttatttac aaatatatat tatatccatg aagcccaatc
      121 ttctttaata gaagattggg ctatttttat ggcaaaggag ggaaaagaaa tgtttcaaaa
      181 taaaggataa cgttatgtca caaagggagt aatggacagt ttgccggtgg aattacaagc
      241 tttatgttgg aatctaatcg atcaaaacgt tcaaaagcaa tttcctttag actatcttca
      301 aatttttgaa ttttctacgg aaaaaggaaa tcaaaagttg gttcatcgtc aagaagaacc
      361 ggaagaaaga aaagagtatc tgatttcacc taagcttcgt ttgaaatcag tgtctcaaaa
      421 aatatgggcc attgattcgg gtgagtatca aacgatgtta ttaccagaag aatactagta
      481 tctaaaagaa aggaacgaaa ggacttgtta gaaacggcta tcgaagtact ggaaaagtgt
      541 gcacagctgg tcactgcttc tgaagagtgg ggctatgaat ccgttacgat ggaaaaagag
      601 gaaattgaaa tgggtatgct tcctgaagat gttcatctac cacgtttagt gatgacacat
      661 ctttatattt attgcgcacc agaagatgga aaagactatg tagtttattt cattacagat
      721 attaccagcc agcgagaatt tgttcgtggg ttactggtag aaggacgatt ggtttggagt
      781 cagattggag gaacggatga ataagatcga ttatttgaga atgattgcga aatgtttaga
      841 agatatcctt accgcgattc atcaaattct gaagaaaaaa ggagaaagaa tatgaaatat
      901 tttcaactag tattgacact tataacggca atggtaattg aagtgcttga acaaaaaata
      961 gcataggaga aaaagagatg attgaaaaag aattagtgac cacacaaaca gaagtttggc
     1021 gagatcctca tcatacccat cgctatgttt tcaaacgaca atgggcgatc aaaggaaaag
     1081 aagcggaaga taaattagca gtagtcatta ctattcgtcc aacagataca gaaccattta
     1141 cgaatgattt gagtatgtta ttaatcgaaa agaatatccg acaattagga tttactggtt
     1201 ttattgctgt gaatcttttt tcgtacacaa aagcgaaaag tcctcgggta tttcttcgag
     1261 gaaatgatga acaatctttg gaaatattaa cgactgtttt tacagaaaag aaaatcaata
     1321 ccattatttt tgcttgtggt tcgattacag cgacgagtca agtggcttat gaacaagcaa
     1381 agactattta cgatcaattg agtgcgaaac aaaagaagat gaccaaagta ttgataaatg
     1441 cagaaggtaa gttatcccac ccactaagta ttcatgttcg taatgaatgg caattggcag
     1501 atagtcaatt attatttcaa gaaaaataac attttatttt ctcatgttac ttataagtag
     1561 ttttacatgc tttttgactt taaaaataca tgtgatgata catgttatat gaattatcaa
     1621 tgtacccagt aatatgctat tttcattatg taaaaaataa cagggggtgt gtagatggag
     1681 attgatgaaa cttgtttgag taactcttat aaaagtatga atgacttttt tgaggaaatg
     1741 gaactggatt cagaattgct ctatcaattt tatcttgctt ttcgagggca acagatttct
     1801 tttccaatga aaatgtacga tcgtgagtta gttagaaaaa gaatcgaaaa catgatagaa
     1861 caggaaaaaa ctgtagatat ccgtcaattg acagaagttt atggtttctc tgcaagatgg
     1921 attcaaaaag taattaaaca aaaagaaagg agacgagtac atggctaagc tgattgtatt
     1981 aggtggttta atttacggtg gatattggtt atatcaatat atgcttgcgc atccgaatat
     2041 agataaagga aaagtaatta agacagttgg ggtaatcata gttggactca tagctctaac
     2101 taagaaaaat aatactaata gcccaaaaat aatgagaact tatcgctgta gaggatgtgg
     2161 aagggaaatt tctactagtt ttaatccatc tgagagtcct caaggaagag accgctgcca
     2221 tacgggctat cgacattatt gggaaagaat cgattaaaag attaccattt agatcaatta
     2281 attgtctgat agaataagta cgtgagggag aaattgaaag ggggaaatat aatgaaaaaa
     2341 tggctgttat tactaatagg aatgggaatt ttattcactg gttgtacatc tgagaatacg
     2401 aggactaaag cgactataga aactgataca acaattgaga ctaaaaaaag taaaacgcaa
     2461 tcaactgaac aaactacaac agaaatgaag caatctgtgg aaacaagtgc aagttcaatc
     2521 actgaatctt cttctgaaga ggttaagaat actttgtggg atacgaataa agcttccaaa
     2581 ttagaaactt ttgtcacaca atggggaaag acattaggtc aagaatataa aagctacaat
     2641 cttcagaata atgtaagtct gtatggcact cctttaccac aagccgtgat taatggcgat
     2701 tggaaaatgg caatcaatga agcaccagtt accgtacaat ggtcagaaga tggaactggt
     2761 catgcagatt tcaatttagt agcagtttat tctgatgtag aaactggaga atatttaggg
     2821 cagcatgttt actttttcgg ttttcaaaat ggacaaccta aagtttattt aacgcaacaa
     2881 aatcaaggta atgaaaataa ttatctgtac tttaacgaaa ctcaaaatca acagttaaaa
     2941 caaggtttca gtgatattgt gaatggacaa actcctcaaa caccagtagt agaagaatct
     3001 actcaacaag caacaactac aacgacacaa tctacaagta gttcaggaat ttcaagttgg
     3061 gaagctgcta aagaatctgt gctaaataat aaagctttat ggttgtatga ttctcctgat
     3121 aaaaatgtat caaatactaa tttaattagc acaaatgaat atatgaaaga tctaatgcaa
     3181 gatgaaaatg gaagctacta ttcaattaat attgtaacgg atgatgatgg aaacacgacc
     3241 atggctggtg gaaaacaatt tcgtgtttat acagatggaa gaatttctca acgtattgga
     3301 atgactaaca attttcaaat gattaaataa ttgaaaatat tatttatcaa agaa
//
LOCUS       DAIGWC010000132         3255 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.136, whole genome shotgun sequence.
ACCESSION   DAIGWC010000132 DAIGWC010000000
VERSION     DAIGWC010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.136"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            511..828
                     /locus_tag="NOB74_002722"
     CDS             511..828
                     /locus_tag="NOB74_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCI1221848.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(919..1284)
                     /locus_tag="NOB74_002723"
     CDS             complement(919..1284)
                     /locus_tag="NOB74_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221849.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1492..1974
                     /locus_tag="NOB74_002724"
     CDS             1492..1974
                     /locus_tag="NOB74_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221850.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2171..3061
                     /locus_tag="NOB74_002725"
     CDS             2171..3061
                     /locus_tag="NOB74_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HCI1221851.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1135 a          498 c          599 g         1023 t
ORIGIN      
        1 catgctgtga gataataata aagaagagtt taaagcgcac cccaaaccac ttccccataa
       61 gtgtattacg ctttaaactc ttttatattt gaattcacta agaagcatac catatatttg
      121 aatttactaa gaagcatacc atatttttga aaaaaagtga gaaaaaaggc ttataattag
      181 gatttagagt aattaattag atgtttattt tataggactg atactataga ttacaaatag
      241 tatcgtattt cgcaatctta aaattatctt cttactgtga ataagataat aaaatttgta
      301 tttgtccttt ttaggtaact tattttaatc tatatacctt tctggatcaa cgaaagttta
      361 tatagtcata acgccgatgg taactatgca ctgtaacgat aatgctgcta aaatatcttt
      421 ttacgaaaaa catcacaagg aaaaacttaa ctatggtatt atctaaacat aattttttcg
      481 gtatttaata tttaattagg aggtaatatt ttgctttttt atagtaattt tatcttaata
      541 gtagcgatat tattacttct gaatatatgg atttttgata ggagtagaaa ttcaagtata
      601 ggttttagaa ctaaacgaag tttgtcttct aaaaaaaatt gggtatactc acaaactatt
      661 ttttatggag gaattgtttt aattagttta ctttcttcaa cactttattc tttgaatatt
      721 atagatgttt ccacctcaaa ttcaatatct attattggaa tcattattgc tgcaattatt
      781 acacaactgt ttttagtgtt tggagagaag aaaagaagta aaaaatagaa aaactagtga
      841 tagttttggt gatataagaa aaacatatat gtataaaaag aagaaagtag cttctctttg
      901 tacatatatg gtttgttttt atggatgccg agctttttta taagataagg ctaccgccca
      961 taacgaccca aggatttgtg gaactaagta aatacctgca agaagcaaga tcagctgggt
     1021 cggttttaaa ggatgataga agtaacgcca ttcagtaaaa ttggcgcaaa ataaatagga
     1081 agtgacagta gatataatat tggcaatgaa taaagatata atacgcctgt tcctttgaaa
     1141 ataatatcca gcaaaaagag ataaaaatat caatgtgatg aacccgctta cggaatgata
     1201 acgaaaatca agcagtaagg cgaaatgcac ataaggaaca aaagataaaa gcaacggaag
     1261 gtttttccag caagttttta tcatctttca tcaccaccta acaagtgtta ttattttgtt
     1321 agttttattg taaattgaat cctgcaataa tcaattactt tttcattatt tctagattaa
     1381 atgaataaac tctcatgcca ttatctctaa aaaaaaagtt tttcccccta atttttttag
     1441 atagaaaatt gtatagtatg atgagagaaa aagtagtttg ggggaacgtt aatgagaaga
     1501 aaagcagtaa tcgatcggct ttatttattt ttttggtttt ttcctatcgt tttgctacct
     1561 tttacatggg taaatgctgt tgtacaaggt gcggagatat taggcctgat ccaaggaagc
     1621 ggatttgtgg tttctaggaa ttttccagct ttgattgttt tctatttagt gataagtgta
     1681 ggtctcttat taccaaaatc tctgatcaat cactacaatt ggcagctgct ttacttttct
     1741 tgcttattag tatttacatc tatgttttct ttgctgcctc gcttgattat cggccctaat
     1801 ggtttgagcg agagtggatt gaaggattta gcttattcct ccatgtattt cttgacgatc
     1861 aaaccatggt tctatttagt aattgcctca tttattcttg caacattttt ttacttctgg
     1921 acagaaatca ggataaaaag tgaacgatct gtatctataa aaaataacta ttgatggtgg
     1981 atcatcagta aaaaaacata tgagctgcgt aaaatgcatg tttctcatat gcttttttta
     2041 ttattatgta aagaatgcga aaaacgttta catgattttt acataactta actatatttt
     2101 tacagcaacc atacgaggga tttacagtcg actgataaac tttagttgta aataagaaag
     2161 gagcaataaa atgaaaaaag tattgtttac tctaggtatg atgggaattc ttttagccgg
     2221 atgcggctca ggatcaggaa atacagatgg ctctgccaca caaaataatt caagtgactc
     2281 aaatgaacaa gtaaaaatcg ttgcggtagg ttcgacagca ttacagccgt tagtcgatgc
     2341 agcacaagaa agctttgtac aagaaaatcc aaattatcaa atctctgtac aaggaggagg
     2401 aagcggaact ggtttgagcc aagtcgaagc tggagcagtt actatcggaa actctgatgt
     2461 atttgcagaa gaaagagacg gagttgatgc ttcaaaatta gtggatcata aagtagcagt
     2521 ggtcgggatg gcaccaatcg tcaataaaga tacagatgtc aaagatatca ccaaacagga
     2581 attgattgat atctttacag gaaaaatcac taactggaag gaagttggcg ggaaagatca
     2641 aaaaatcaac gtcgtgaacc gtgcaaacgg cagcggtacc cgcgcgacat tcgaaaaatg
     2701 gggactggat ggtgctaccc ctgtgcagtc ccaagaacaa gattcatcag gaacagttcg
     2761 gcagctggta agtcaaacac caggagcaat cagctattta gctttctcat atctcgatga
     2821 ttccacacaa gcactaagta tcgacggtgt agaaccaaaa gaagagaatg tagcagataa
     2881 cagctgggga atctggtcat atgaacatat gtacacgaac ggaaaacctt cccctgaagt
     2941 ccaaaaattc ttagactaca tgatgacaga agaaatccaa gaaggacctg tcaaagaatt
     3001 gggctattta ccaatcacaa tgatggaagt agaacgtgat cacgaaggaa atatcaaata
     3061 actagcagat aaacatgcca cggtagtcgt tactattaag gaaaaatcaa ctatgtttcc
     3121 ccacatatac atttttcctt taattgtgaa aaatagttcc tcatattttg ccgttttttg
     3181 agctaatacc gagggtcagc tgattgaaca ccgtttattc gaaaaaaaga gctacgacat
     3241 agaactgtcg taact
//
LOCUS       DAIGWC010000133         3163 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.137, whole genome shotgun sequence.
ACCESSION   DAIGWC010000133 DAIGWC010000000
VERSION     DAIGWC010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.137"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            110..577
                     /locus_tag="NOB74_002726"
     CDS             110..577
                     /locus_tag="NOB74_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HCI1221852.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            584..3076
                     /locus_tag="NOB74_002727"
     CDS             584..3076
                     /locus_tag="NOB74_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HCI1221853.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
BASE COUNT         1107 a          519 c          693 g          844 t
ORIGIN      
        1 ttttttttgt tgattctaaa ggatttattt aacaaaaagc gttcttcttt ctttctatta
       61 tcaaattcgt tataattaag gtcaatatta gtcaaaggga atgaataaga tggcacatca
      121 gaatacctcg gatttaattg aatcatatat aaagaaaatt ctggaaaata gtgaaatgat
      181 cgagattcga aggattgaaa tggcagacct ctttaactgt gttccttcac aaatcaacta
      241 tgtgattaat acccgtttta ccatccaacg tggttatcta gtagaaagca aacgtggtgg
      301 tggtggttat atacgaattg caaaagtaag gatttcagat aaaaaacaat tacttgagca
      361 gataaatcag ttatttgatg atacaatcag tgagaaaaat gcttttgcta ttattcaaaa
      421 actttatgaa gaccaaataa ttacaaaaaa agaaggaaac ttgatgttga gtgcaattgc
      481 aaaaaacaca ttgaatttca atgaatatga agatcataca cgtgctcgga ttctccgagc
      541 atttctggaa cgtttaagtt atgaagatgg gaagtgagat tagatggaag aactttttac
      601 tgaaagagcc caagcagtat tagaaattgc acaagaagaa gcaaaacggt tgaaacatca
      661 atcagttagt tcagaacatg ttttactagc cttagtggtc gagcaaaatg gaattgctgg
      721 aaaagtatta cgtgaaatgg atttgaatga aacggaaatt tatgaagaaa ttgaacatct
      781 gattggttat ggtggtatcc gttcttaccc taaaggagtc tttcttccat attcaccaag
      841 aatgaaacaa gtttttgctt tagctagcag cgaagtgaag aaaactggtt ctcaaaaagt
      901 tggaacagaa catattttga tgagcttatt aaaagatgaa agtatcatgg ctactcgaat
      961 catgatcaac ttaggtatca gcctttcaaa agcccgtcaa gttctgaaac aaaaaatggg
     1021 gctagctggt gattctgctg gaaaaggaat gaatcgtcgt agaaatgtaa atgtacaaga
     1081 taaacggcaa acaccgcaag gaacacctac gctagattca ttagcacgtg atttgacgaa
     1141 attagcaaaa gaaaacaagc tggacccagt tgttggtcgt tcgagagaag tgaaacggct
     1201 tatccagatt cttagccgac ggacaaagaa taaccctgta ctggtgggtg aacctggtgt
     1261 aggcaaaaca gccattgctg aagggttagc tcaaaaaatc attttaggtg aagtgccaga
     1321 agacatgcaa gaaaagcgcc tgatgatgct tgatatggga tctttggttg ctggtacgaa
     1381 atatcgcggt gaatttgaag atcgaatgaa aaaggtcatc gacgaaatct ataatgatgg
     1441 tcaagtaatc ttattcattg atgaattgca taccttaatt ggtgcaggtg gagcagaagg
     1501 agcaattgat gcttcgaata tcttgaaacc ggcgttagct cgaggagaat tacaaacgat
     1561 cggagcaacg accctagatg aatatcaaaa atatatcgaa aaagattctg cattagagcg
     1621 acgttttgct cgcattcaag tagatgagcc aactcctgaa gaagcagaag tgattcttca
     1681 aggattacgt acaagatatg aagagcacca tggagtggag atcacagatg aagctgtacg
     1741 agcagcagtc aatctttctg ttcgttatat cacttctcgt caactacccg ataaagcaat
     1801 tgatttgatc gatgaatcag cagcgaaagt ccgtttggat caaaccgatc acttaacaaa
     1861 atcaactgtg atcaaactag aaatcgatga actagtacaa gaaaaggaag cagcgatcca
     1921 aaaacaagac tttgaaaatg ctgctcaatt acgcagacaa gaaaaagcac tacgtaaaaa
     1981 gctgcaaaaa gtttctgcaa ttgaagcaaa acaggagcaa ggttattctg atcgtgtaac
     2041 agaagaagat gttgctacag ttgtatcgga gtggactggt gtccctctac agcagttgga
     2101 gaaaaaagaa agcgaacgct tgttagaact ggaaggactt ctgcatgaac gtgtcgttgg
     2161 tcaagatgag gctgtcaaag cagtttcacg tgcgatccgc cgtgcacgaa gcggattgaa
     2221 agatcctgat cgtccaattg gttcattcat gttccttgga ccaactggtg tcggaaaaac
     2281 agaattggcc aaagcacttt cagaagtcat gtttggaagt gaagatgccc tgatccgtgt
     2341 tgatatgtca gaatttatgg aaaaatacag tacaagccga ttaatcgggt ctcctccagg
     2401 atacgtaggg tatgatgaag gtggacagtt gacagaaaaa attcgtcaaa aaccatattc
     2461 agtgattctc ttagatgaag tggagaaagc acatccagac gttttcaatt tacttctgca
     2521 agtattggat gatggtcatt taacagattc taaaggtaga aaagtggact ttagaaatac
     2581 aatcatgatt atgacttcaa atatcggagc gacacaaatt cgagaagaaa aaaatgtcgg
     2641 attcaatgtc caagatgtta ctaaagatca caaagccatg caaaaacgta tcttagaaga
     2701 gttaaagaaa gctttccgac ctgaattctt gaatcgaatc gatgagactg tcgtcttcca
     2761 ttcattgagt aaagatgaaa tccatacaat cgtccaaatc atgagcaaag cgattatcaa
     2821 acgattgaaa gaacaagata ttcaagtgaa aatcacacca tctgcaatcg atgtgatcgg
     2881 gaaagctgga tttgatcctg aatatggtgc acgtccaatc cgtcgcgcac ttcaaaaaga
     2941 aattgaagat cgattgagcg aggctttgct tggcggagaa attcgtttag gtgaccacgt
     3001 aacagtaggt gcttcaaaag gtaagatcac attgaatgtt cgcggaccta aaaaggaaac
     3061 agtaggttcc ctatagttac ttggcctgtg tagctgaatt tttataatag taagacttga
     3121 ttaagaggtt gtgacaagat ttttgtcaca atctcttttt ata
//
LOCUS       DAIGWC010000134         3153 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.138, whole genome shotgun sequence.
ACCESSION   DAIGWC010000134 DAIGWC010000000
VERSION     DAIGWC010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.138"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            37..1671
                     /locus_tag="NOB74_002728"
     CDS             37..1671
                     /locus_tag="NOB74_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221854.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(1938..3107)
                     /locus_tag="NOB74_002729"
     CDS             complement(1938..3107)
                     /locus_tag="NOB74_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCI1221855.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
BASE COUNT         1028 a          456 c          491 g         1178 t
ORIGIN      
        1 aaaaaataaa tgatactata tgtaatataa aaaaacatga ggtggtatat gaatttgaaa
       61 aaaatttttt ctgtaaaaat atttatagtt tatgcatttg ttagtttatt atatttattt
      121 ccagcattta aaaacatgga aatatttggc ttttatgata cggcatttca cattaatcgt
      181 gcgttaagtt tagaatctat ttttagctcc cctattaatt ttgaaacgtt tagatcatat
      241 ggcatgcaag taaataattt ttacccatgg ttaactctat atcctttatt tttattgatc
      301 aagtttacta atttagcaat aggctataac ctttttcttt atattgttac gctcattact
      361 ctatttatat gtcattatgt aatgtatgaa attaccaaaa aacatgttac tagctccttt
      421 ttcgctatta tatatacaac atcttctttt aggagtgtag aaatatttct tcgaggggca
      481 atgggggaat tactcgcaat gtcaatactt cctcttattt tactcgggtt tataaagctt
      541 tacgactcaa aaaaagaatc ttgggttatg ttggcgatta gcatgacttt attaatttac
      601 actcatgttc tttctgtagc tatgactatg gtaatgatta taattgcttt aattattcaa
      661 ttttatcgga aaaagaaaat agaaatcttc ttaattatta aattaataaa agctgctata
      721 gttactttac ttctttcact agcgtttata ggtcctatga ttgagcagac attgtatcaa
      781 gatctgaata gaccttatgt ggatatatta caaaaaagag caatttatct gggtaaagag
      841 tttttgattg gaagtataga ttcagaatta ctatcatttg gtattggctt aactttgctt
      901 atttgtttaa ttatactaac atttaacttt aaaaaattag gaatcttatc taaaatcact
      961 tatataatgg gtataatatc tattctactt tgtacaaaaa tatttccatg gtttgcctta
     1021 caaaatactc ctttaaatat tattcaagct ccttggcgtt ttatgatatt ttcaacattg
     1081 ttcatatctt tttcagtatc tctatttatt tctccacagt tggaaaaatt ttcttataca
     1141 aggagaagaa attttatact attattaata ttagctattt caattttaaa ttattcatca
     1201 gtagttaaca tggtgaaaga aatgaatttt caaggaactt attctaatga acaaatggaa
     1261 aataaacttg aagaatttga gaattttgat tatgtaccta taggctataa aaaagatcaa
     1321 ttgcttttga aaaaccatca agttacagaa gatggtcaag ttatttatag tagcttttct
     1381 ccaaataaag atgaaattac atttacgttt aaatcttcaa aaggcaaaac aatagtttta
     1441 cctgtattcc ggtataaagg attaacggtt actgttaatt caaaaaatgc tacagtacta
     1501 aaacaaggag gtccttttgt tacagtaaaa agtgaaagtg gaataaataa agtaacaatc
     1561 aggtattcat acacattttt ttctaaaatc tcattattta tttctataat cacgctaatt
     1621 gttcttcttt tttattgcat aaaattaaaa ataagaacaa gccatgaatg atttgctagc
     1681 acatatttta gcaatctaaa gatactattt tagatttaat aggccctttg tcaaataatg
     1741 ttggtaaaga gaaatcttag aataatttgg acagaacaga aagaagaaca cctctttctg
     1801 ttctgtttat ttggaattaa agtctgtagc aaaaattgat ttttagattt gtcccacact
     1861 ctttcctacg tttagtcgag tacttttttt aagcaaatgc tattcaaaga agtagtattt
     1921 gctatctttt catcatatca gctatttgcc aacttagtag ttccttccat caggtcatag
     1981 atttggtttc ttagatcagc agtaggcagt ttgatagttt tgtcagcttt tatattgctt
     2041 tccatgatga tagcatcctg tgaatctttg ctaaatatag cagatgtatc aaaagagtcg
     2101 atatttcctt gcgacaggat ataattatct ccgctatata ccccaccact atatggatgt
     2161 ccattcgcat tttcacgcca taatgagaag agtaagtctt tggaaactag ttttccagat
     2221 aaaacttgtg taaacagcgt atttaaatca tagacggaca tactgatatt accagtccct
     2281 aattcgttat ggatctctgt ttcagattct gtcagtggtt taaagtaatc atcctcttta
     2341 gacatttgat aggatagtgc atgattggat gaatttttga cttggtcata aaattttgta
     2401 tgctgtaatc ctaaaggttc gatgatatca tcggtcaata atttttcata cggttgattt
     2461 gttaatttga tcaaaattcc agtcaatatg gtaaagttca atgaatcata atgagaggtc
     2521 tgataatctg taaattttaa gtgctgaatc gcaaattgaa cgacttcttc atcagtcatc
     2581 ggtatggttg gagaagcagt tcggtgcaag cctgagcgca tatacagcaa gtcacggata
     2641 gtaatttgct ggctgccagc aatttgtgga tagaattgag ccagcttagt atctaaagaa
     2701 aggtgcccac gctcgacttg ttttaaaatc aaaagagtag tcaatgcttt ttgaaccgaa
     2761 ccaatctgat aataaagaga aggatcattt ggttgttgcg tgagtttatt cgcatagcca
     2821 tagccttttt ccatgatgat gcgattattt ttctttacgt aaattgagcc aatataatca
     2881 ttttttctta atagttgatc gattttttca acgagctgtt gttcattggt agtcagtatc
     2941 aacttttttt gagctgattg agcatgggca actatctgag agtgttcatt attgtaaaat
     3001 tgccatccaa gaatagttcc tgtagagaac gcactaaggc taaacaacac gacaacgatc
     3061 attaaaaatg aatattttct ttttttagca tgttttcctt ttttcataat agtttattta
     3121 gtctcctttc ttttttacag aaagaataaa gct
//
LOCUS       DAIGWC010000135         3099 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.139, whole genome shotgun sequence.
ACCESSION   DAIGWC010000135 DAIGWC010000000
VERSION     DAIGWC010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.139"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            468..2105
                     /locus_tag="NOB74_002730"
     CDS             468..2105
                     /locus_tag="NOB74_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221856.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2250..2990)
                     /gene="truA"
                     /locus_tag="NOB74_002731"
     CDS             complement(2250..2990)
                     /gene="truA"
                     /locus_tag="NOB74_002731"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCI1221857.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
BASE COUNT          962 a          531 c          433 g         1173 t
ORIGIN      
        1 taatcagaat cgtacaaata tttaataacc aaatatatag aacataactt aatattaagt
       61 tatttgaaat tccataaaaa acgactgcag gaattattgt aagaaaagga taaaaatagt
      121 tcagtccatc tccataattg ttaaatgttg tatagttgat tggcccttca aaaatagaag
      181 ataacccttt gattcgtgaa agatgaaaag ataaatcacc tgttgtataa atttcttgag
      241 catttctcat aaaatttact gaatataaag tactaagtaa gataagaact actaaaagaa
      301 atgctttttt acttattttc atagatttgt tgttctcctt ttttaattct attttcagta
      361 tactagaatt gtcttttttt aataagtttt gcgttaaatt tttcatagca ctagtatgat
      421 atactagaaa agaatcaatt tttattactt ttaaatagga gaaaaaaatg aaaaaaaaca
      481 aaaaccaaat aatagatatc atttttatgt tatttctaag ttttgcttac gtcatccctc
      541 tattcatgtc tatgggaatc tatcatagtg tcaatcagga tacttacttt catttatctc
      601 gaatcatagg actagataat gtatggagtt ctccagtaaa cttcaataac ttcgatcatc
      661 atggaacaat gatgaatatt ttttatccat ggcttactct ttatccagct tttttatttt
      721 ataaaatgat gggaaatctt gttttaagtt ataatatcta ctattttttt atcacttttt
      781 taacaatggt cgtttcttat ttttctatga aacaaataaa aaacaatcgt tatatttcgc
      841 tgttattttc gattatttat acattttccg cctatcgtgc cattgacata ttccatcgtg
      901 cttcattggg agaagctgtc gctttaacat ttttgccttt gatactaatg gggtgttacg
      961 aaatttatat tagagattac caaaaatggt actggttgtc tattggcatg acgctagtag
     1021 tgtatactca tttactttct gtcgctatgg tttctgtatt tattggagga acgttgtttc
     1081 tttcttttta tttttgggac caaaaaatcg ctagactctt aagtctttta aaagctaccg
     1141 tcctcacctt ttttttaagt gcgggattct taattccttt tattcaacaa tctagagcac
     1201 aagaattgaa agtcccactg ggaaaagaat taagtggtat ggctcctagt gatatgctga
     1261 cacacatttt aaataataac tataacaact atactattgg attattctta tttctcggat
     1321 tgattggtgc ttttattttt ataaaaaaat taactgctga tgatttattt attttctttc
     1381 ttggtgtatt tgttcttttt tgttcaacca atttatttcc ttggcaactt tttaaccata
     1441 caccagttaa gagtctacaa tttgtctggc ggttaaatgg tttttcttct ttatttatag
     1501 cctatacgat gagtatagtg atctattata ttttttctac taaaaataat tcatggaaaa
     1561 taatggtctt tacgtttctt gcactaatat tgcatctctc aggagtaagc aattctatcc
     1621 atgctaacaa agattcatta acacttatag cacctgaaga cgctgttgct atagctgaaa
     1681 attacaatca tactgattat gcaaacaaag agtcaatcta tcatcctgat atgattaata
     1741 atgatcaata tttactaggt aaccaggaaa taaatccaac aactcatttt atgagtaaca
     1801 aacttacaat tgaattagat aattcgaata ataaaaatac tgtcttgacg acacctattt
     1861 atcgttataa agggcaagtg gcttctatta atggcaaact agtacaaaca aaattatcta
     1921 agtttggcac aactgaatta actattcctc caggtataaa taaagtcgtt attacttatc
     1981 agtacacaaa actagcaatt gcttcaagat atttatctat cgttactttg attttatttt
     2041 tactttatcg atttactttt tctaaacaaa aacaaccgag aagagaagta caacattctc
     2101 actagatttt tatttaagaa agacttttta gctgtacaca taaacaggct aaaaagtctt
     2161 tttttatatt tctttaattt gcttcataca ttatttaaca tcgatattta tactgtgaaa
     2221 catgcgtttc atccattatc aaagtatttt tatcgataat aaacttcatc caaaaacaga
     2281 ccttgtgcag ggacggtttc tcctgcatgt tgccgcactt tgctttcaaa tatttcatcg
     2341 attgtttcta tcggcatggc acctgtgccg atttctagta atgtccccat gataatccgc
     2401 accattttat ataagaatcc gtctccgaca aaagtaaaat gaagcatttc tccctttcgt
     2461 tcgatagata attcatcaat cgtacgcact gtggattttt ttgatttttt caatgcagaa
     2521 aaaccaatga aatcatgtgt acccactaat ttttcgcaag ctgcattcag cttgtccata
     2581 tccaactctt gagggaaata aaagctgtgg tttcgctcaa atgctgaagg aatcacgttg
     2641 ttccaaacat aatagctgta ttttttgccc accgcattat atcttgaatg gaagcgctca
     2701 ggcatttctt cgattctttt gatgacaata tcccgcggaa ggtaacgatt cataaagtcg
     2761 atcatttctg ccagtccaat ttctgtgttt gttttaaaat ttgctacttg tcctcgcgca
     2821 tgggtgccag catctgttct tcctgatcca ataatttcta tctcttcatt tgtcatctga
     2881 tgcaatactt tttcgatttt tccttgaatg gttttatcgt catctccaag tctttgccat
     2941 cctgaatatc tttttccgtc atattcgatt gtcaacttga tgtttctcat attttagtgg
     3001 ctcctctgtc ttccatttgg tcttctctct acctttttaa gattgtagca caaaatatag
     3061 ctcctttctt ctctaaaaca gaagctatac aagaaaact
//
LOCUS       DAIGWC010000136         3031 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.140, whole genome shotgun sequence.
ACCESSION   DAIGWC010000136 DAIGWC010000000
VERSION     DAIGWC010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.140"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            581..1540
                     /locus_tag="NOB74_002732"
     CDS             581..1540
                     /locus_tag="NOB74_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1221858.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(1527..2132)
                     /locus_tag="NOB74_002733"
     CDS             complement(1527..2132)
                     /locus_tag="NOB74_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221859.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
     gene            complement(2372..>3031)
                     /locus_tag="NOB74_002734"
     CDS             complement(2372..>3031)
                     /locus_tag="NOB74_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1221860.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSTGQKFDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIRKWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          988 a          504 c          471 g         1068 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttaccttcgc cgattgtaaa attaagctag acaactaaaa aagtcatttg tgctacactc
      541 aaaatagttc cgtcgaaaga attataagga gtgagtacaa atgacctata cccatcttac
      601 accaactgaa ctcgtaatga tagaagctta tttcaatcaa tcacactctg tttcaaaagt
      661 agcccatctg gtacaacgtt ctcgacaaac catttataat gtctatcgtt ttcttaaatc
      721 tggtggaagc gcaataagct actatgaaca atataagaaa aacaaacgta actgcggaag
      781 acgtccgatt gtgttaccag atgggcaaca agaatacatt caaaaaaagg tggctcaagg
      841 gtggactcca gatgtcctta ttggtcgagc agagtttcct attgcttgtt cggtacgtac
      901 actatatcgg atgtttaaag ataaaacctt tgaccctcac gatttaccaa tgaaagggaa
      961 aagaaaacca aacggacata aagaaaaaag aggaaaacaa gcttttcgcc gttcgattca
     1021 ggatagaaca actgattata tacagttcaa tcatgagttt ggtcacctag aaggtgacac
     1081 cattgtcggt ggaaaacata aaagtgcggt gatcacgtta gttgagcgat tatctaaagt
     1141 gatcatcacc ttgaaacccg ctggtaggca agctatagat attgagaata gactgaatca
     1201 atggtttcaa tctgtaccga aacacttgtt taaatccatc acatttgatt gtggaaaaga
     1261 gttctcgaat tggaaaaaga ttagtaatac caatgatatt tcgatttatt tcgctgatcc
     1321 aggaacacct tctcaacgag gactaaatga acattcgaat ggcttattac gtaaagatgg
     1381 cttatataaa gctatggatt ttaataaggt atccgaaacc tttatccaat cggtggcatc
     1441 aaaacgaaat catattccta gaaaatcatt acactatcgc acaccattgg aagtattttt
     1501 gagttacgta ggtaaagatg atttgtctag cttaatttga caaacgaaac tttgtaaaaa
     1561 tattcgattg aatattctat ttggcacgac tcacttggca gtatatgtat gtcaatattt
     1621 ttcatctgtt tcataggtat ttcaaaatct aaactattaa aaacatataa ttccctgtaa
     1681 ttatttacat ctaactctac taaatttatc tttggaacaa tagatcctcc acccattcca
     1741 ccataataaa aaaaatcttg ttctctatca aaatagcaca tattaagctc agtttgttta
     1801 tcatcctcaa taattttata aatcaaacct atataatcat gaatgctggc aaaaattttt
     1861 tttaagtcaa gttctaaatc ttcttcgaaa acacatttaa tttctcctac tgataattga
     1921 tactctatat tacatgactt aattagtttt ttagatcccc cctccagata ggcatatgtt
     1981 tcaataatta tgttcttttt attgcttggc aaatttccgt tatttattgc ataaattaaa
     2041 aatgactgtc tatttagccc ataatctaat acaacttctt catactcata tttctttaaa
     2101 tatttaatat gaaaatatgc tgaattaatc aaaactcgag tgttactgtt gttatttatt
     2161 gttgttctat tgtgtataaa attgtatagg ttgtcatatt ttcttggttt agtgaactac
     2221 tcaccactta gctaaaccta acggtttctt acgtttgaag tgggagcttc ttgggaagag
     2281 agcatacttg atagcgtatt actttactaa cagaggtgcc tcttatttac caagctatcc
     2341 ccgtagttcc tacggttctt gtttatttga tctaagccaa tcccatagag tgtagcctta
     2401 gaccttcggt caggatattg atactagcgt tgatatctcg gtcatgatga gtatgacaaa
     2461 tagggcaagt ccattttcga atttcgagag atttcttgcc gtctttatgt ccacaattcg
     2521 aacagatttg gctagatgga aaccacttat ctactttgat gattttccga ccgtaccagt
     2581 cagccttgta ttgtaattta gacacaaaac tagaccaaga aacatccgaa atactttttg
     2641 ctagtttatg attacgcaac atgccttttg tgtttaagtc ttcaatacag atgatatcgt
     2701 gatttttgat aatttctgta ctcaacttat tcagaaaatc agtacgttga ttcattactt
     2761 tttcatgcaa tcgtgctact ttacgttttt gtgtttgata atttctagct tcaaacagat
     2821 tgataccttt ttgtttagct aataaggcac gtcttgacaa cttacgttgt tcacgtttga
     2881 gtttcttttc cattttggac gtaaatttat tattatcaaa tttttgaccg gtagaaagaa
     2941 ttgcaaagtc tataatacct aggtcaatac caacagcaga attagattta ggtagttcgc
     3001 gaacttcttc tttgcataac aaagaaatat a
//
LOCUS       DAIGWC010000137         2933 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.141, whole genome shotgun sequence.
ACCESSION   DAIGWC010000137 DAIGWC010000000
VERSION     DAIGWC010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.141"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..482
                     /locus_tag="NOB74_002735"
     CDS             <1..482
                     /locus_tag="NOB74_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI1221861.1"
                     /translation="LTYRTEDEDSIRYFVLFTGFEINKTKKFVEVSVNPDLEYIINGL
                     TAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYYVVRIEEFRSLMDIPEYYQMGNI
                     DQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLEFTFSSLTSDLPKISLRNWLEE"
     gene            complement(619..1035)
                     /locus_tag="NOB74_002736"
     CDS             complement(619..1035)
                     /locus_tag="NOB74_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221862.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1038..1322)
                     /locus_tag="NOB74_002737"
     CDS             complement(1038..1322)
                     /locus_tag="NOB74_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221863.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            complement(2022..2117)
                     /locus_tag="NOB74_002738"
     CDS             complement(2022..2117)
                     /locus_tag="NOB74_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCI1221864.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            2770..>2933
                     /locus_tag="NOB74_002739"
     CDS             2770..>2933
                     /locus_tag="NOB74_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HCI1221865.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELK"
BASE COUNT          931 a          469 c          550 g          983 t
ORIGIN      
        1 atcttactta ccgtactgaa gatgaggatt ctattcgcta ctttgttttg tttactggtt
       61 ttgaaatcaa taaaacaaaa aagtttgttg aagtcagtgt taatccggac ctagaatata
      121 ttattaatgg tttaacagct gaatttagta gatttgaatt atctgctttc acgtcgttgc
      181 gttctacgta tgcaaaaact ctattccgac tgcttatgca gtaccgttct actggttatt
      241 atgtagttcg tattgaagag tttaggagct taatggatat cccagaatac tatcaaatgg
      301 gtaacattga tcaaaaagta ttaaatcctg cattacgaga actaaaaaaa tacttcaatg
      361 atcttaaagt cacaaaaata aaagcaaaaa agggcaataa aatcgccaaa ttagaattta
      421 ctttttcaag cctaacgtca gatttgccaa agatttctct gcgtaactgg ttagaagaat
      481 aaataaaaaa gaactcgccc cccttacatt aagcaagtag acaagtccct tacaaccgac
      541 taagattgct agtacattct agcatattgt atggggcttc taaataaaaa acagatagga
      601 ataactccta tctgtttttt atcgttttag aaaatttgtt gggtcgaaat ttctagaagt
      661 gactgtttga ctggtttctt tttgatgatt ctttggtcga tttcgatttg atggatttag
      721 tttagcttcg attttttctt tcacttcttg atatacttta gaatttgtgc caataagaac
      781 gcctgtatct tttagatata aatcagcaaa ttctgcgatg atttcagtca tgatggaaat
      841 ttcttttccc atagcattta gttttgcctg attgctggta gtggtcgtgt tggtatcggg
      901 ttcataactc atacataaaa agcgaatggc ttccgagtag ttattgatat ctggattttt
      961 ttcgatgatg gaatctaaaa cgtcaacatg actagggtac aaagtaacat gtttttggac
     1021 agaagttttt ctcatggtta tatcattcct ccgataagca tttcaatgat ttgattattt
     1081 gtgtagacat actcgcttaa tatttgagta ttttctgttt ggatagcaat aaatttatcg
     1141 agcaataaat cgaattggtc ttttttgtaa gtcgtaagtt gacggtcaaa atcactttcg
     1201 attaaaactt ttagatattt atttcgactc catttttctc ctgttttatt cgtgagttct
     1261 tggcaacgtt tgtctattgt tgcaacaaac tttggatcaa tattccgaac taaaatgtcc
     1321 ataaaaaatc tccttttgca attatgtata atttatgtat accatacaaa tactatattt
     1381 gtatagctgt tttttgccaa aatgctatac ataagctacc cacgatggcg aaaaagtgat
     1441 atcaaatttt tttctgagaa acgtgatagg cacagcctat ctacccactt tttttagaaa
     1501 gtgggtacac gtttccttat gctctttaaa attcgggggg gagtgctgca cgtgtaatcg
     1561 ataaccaaat ttaacagacg aaaaattgtt ggaatataaa aatatgacac ccgaaagaaa
     1621 acgatcgttg gaaaaattaa tgcaactagt gaacgaagac ggcggaattt cagacgcagc
     1681 ttttgacgca tggagcgaat ttcatggaga atataattaa gtgggtttaa atggctctaa
     1741 aatcgcttct aagagttttt tagcttggac caatgaaata caccaaaaac taaataaaac
     1801 gtcttaaatc gaaaaatacg agctctcaga gcgactttat ttgtaaatgt tgcatataag
     1861 aaataattac ggattttaga cttttgtagg atatttttga aataaatatt tatttctgtt
     1921 ataatttgat tgcaaataag tgaacacgaa acacacgaaa tccccagaga ggtcggattc
     1981 tctggggctt tttttgtggg ctgagtcgcc ttaattaagt tttacttctt gtttcggtta
     2041 ttcaaccagt aactgaacaa agcgcttaaa agcccaacaa gaagggagca aataaagtta
     2101 gtgaacacga aacacacctc cttccagtcg caagactgtc ggataggcga caatcaatta
     2161 tacaataaaa aagcaaaaat aagcctaagt tttttattgc cttggggttg ttagggcttg
     2221 ccctgaccgc ctgtaaggcg ctttagaacg aaggacatag tttttatcga atcttgtctt
     2281 agaacggctt agacgagctc tcaggacgcc acaaaggagt ccctaatgaa ttatttttgg
     2341 cgaaggagcc taaaggcgac tgctgcaagt aaaatgtgag agcgtagcga tcactccttc
     2401 ttacagcgac catagggagc tagattggca gtttaatatc atgcgcgaac ctgtttattt
     2461 taaaaagtgg gtgatttttt ggcgggaaat tttgctcgcg cgcgcgcgtt tattttattt
     2521 attttttaaa gattttttag aacccttttt agggggcagt tgagccttac tctcccaacg
     2581 gatacagaag ggtactaaca actttttatc tgagtactaa caacttttta tctgagtact
     2641 aacaactttt tatctgagta ctaacaactt tttatctgag tactaatatc cttttgtata
     2701 ataacaacca acctatttac gagttggttg ttaaaggtta ttatttattt gtaagggggg
     2761 aagaaaggaa tggatgaaaa aacggaatta acagtcaaat atcaaaatga attgaattta
     2821 gtaccgctga aaaatttcaa tgctaagcag atggatttat tttttgcatt atgcgctcgt
     2881 atgaaagatc gtggtttgaa aaaagttaga ttttctttcg aggaattaaa aga
//
LOCUS       DAIGWC010000138         2915 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.142, whole genome shotgun sequence.
ACCESSION   DAIGWC010000138 DAIGWC010000000
VERSION     DAIGWC010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.142"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(46..1365)
                     /locus_tag="NOB74_002740"
     CDS             complement(46..1365)
                     /locus_tag="NOB74_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1221866.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1362..2015)
                     /locus_tag="NOB74_002741"
     CDS             complement(1362..2015)
                     /locus_tag="NOB74_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1221867.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2303..>2915
                     /locus_tag="NOB74_002742"
     CDS             2303..>2915
                     /locus_tag="NOB74_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1221868.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFL"
BASE COUNT          956 a          474 c          321 g         1164 t
ORIGIN      
        1 aataagtctc tatttttcaa taactattgc aaaattatat cttaattaag aaaatatttt
       61 tattttaaag ataaaaaatt cttcatcctg caatacttta tattctatat tgtaattatt
      121 cagaatatta cttacaatat ataaacctaa tccattacta ttttccttat ttaaatcaaa
      181 tttaacatca aatattttat ccatattcga aattttattg ttaccgtatg aattctctat
      241 atataaccaa tcattaacta tcccaatatt aattacccca tttacatcag tatattttac
      301 cgcattacta atcaaattag atagaataat ctttaaagct gtttttccta tataaacatt
      361 ctcgtctaat atataattat tgacagttat tttcttttga tttgctaata tttcatactt
      421 ttttaatatg tcttctaatg tatcatttat tttcaaatat tcttcatcat tattcaaatt
      481 ttctatagaa tgaactgata atatttgaga aatatttttt gttaaactat caacgatttc
      541 aatacattca ttaatataaa tatctctttc tttatatttt ccaatattgt atttcatgtt
      601 ttccagtatt attttaagac tagcaagagg ggttttaagt tcatgggatg cacctttaaa
      661 aaagtcatat tttaactttt ctaattttaa aatttcttta tttttaaatt ccaaatcgtc
      721 aattgttctt aataaagtag aatacaaatc attaatttgt tgttttaatt ctccaacttc
      781 atcattagag ctaactttta aactcatttt tttatcaagt ttcatcattt tatcagtaac
      841 aatttttatt tcttgtatat tattttttat tgattttgca taaattaaag aaataatagc
      901 agaaaataaa attgatatta ataaagaata tggtaaaaat ttaaggctta aatctttcgc
      961 atctttttgc atatcagctg tagaaacaaa ttgtagattt gtttttttac catcattaag
     1021 ctttatttct ctttcttcaa ttatcaaaga attactatca ctttctaaat taacatttat
     1081 attatctttg atttgtattt cattcttatt atttttttct tttatgaata cttttatttc
     1141 actactcttg gaataaaact ccaaagtttg ttctatatat tttatttctt ttccattcat
     1201 attactagaa atttcatttg ccatattatg aatcttttct tttctcgtct ccaaatatgt
     1261 tttaggaaag ataaaaaaaa ttaatgaatg aactaatata attattattc caagaacaga
     1321 aaatatttgt atgaacattt ttggaaatat ctttaatttt ttcattttct ctccaattta
     1381 tatcctacat ttcttatagt agttatacag tctaattgta atttttttct aagttctttt
     1441 atatatacat ctattactcg atcataagga gtttcttcgc tatctttcca tacataatca
     1501 ataatttgca ttcttgttaa cacttgtcca ttattatcca ataaacattt taatacttct
     1561 agttcttttg catttacatc tatttcttca ccatttattt tagctgtata gctattaaaa
     1621 ttaaccgata gatccttata ttcaaacttc tctaaatgtc cataattctt cttaattaaa
     1681 gaatctattc tagcttttaa gaccggcaat gaaaatggct tttctacata tccgtctact
     1741 aaattagtaa atgcatcaat tttatattct tcatcactaa atgcagtcaa gattagaatt
     1801 ggtaaattgc ttttctttct aatttctttc aacacttcta aaccatttat aaaaggtatc
     1861 tgaatgtcta agataaccaa atttatatcg ctattaaatt ttgacaaggc ttctcttcca
     1921 tctttagctt gaataacagt atatccaaat tctgaaagat attcacttat tccctctctt
     1981 atcatattat catcttcaac agttaatatt ttcatatata cctccactta agcctataca
     2041 ctagatatta tacagcatat tatggctcta taatatctag tgttggtgac accttctgtt
     2101 gccaatactt tttctttttt ctaataaatg caaacagaca ccttgaaatc ctttagaata
     2161 aagggttcta taatattttg tgttgttgga aaatcgaagg cgattttcta ctaacacttt
     2221 ttcttcgttt caactcaaaa agagactcac ttttggtaaa atttagtcga ccaaaacatc
     2281 accctaccaa aggagtcgct ctatggataa tcatactaga aaattactcg gattaacaga
     2341 taaacattta ttttttgatg aagaatggct gattgaaaaa gaatataaag gcgttcaagc
     2401 gcagtttatt aaagggagat tggatgactc accttcccat tgtgaacact gtggatcgat
     2461 tcgtattatc cgcaacggtt cctatacgac acgtactcag atattgaaag tcaaagaaaa
     2521 gttgactatt ttagaattaa aacgtacccg ttttctatgc tatgattgtg ggcagacctt
     2581 ttctgcgaaa acggacttag ttgatgaaca tcatcaacta acaaaggaac tgaagcaggc
     2641 gattctcata gaactgtacg aaaatcaatc acgtaaacta atcgctaaga agtacttcgt
     2701 ctcggatggg acggtgacac ggatcttgcg tgaagcaacg aagcattacc agccacgtat
     2761 gaacttcctt ccgacggtgt tgtgtatgga tgagttcaaa tcaatgaagt ctgtttctgg
     2821 ttccatgagt tttatttgtg ttgatgggac aacccatcag ctatttacga tccttgaaga
     2881 tcgcagactt tacaaactaa ctcaatactt cctgc
//
LOCUS       DAIGWC010000139         2618 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.143, whole genome shotgun sequence.
ACCESSION   DAIGWC010000139 DAIGWC010000000
VERSION     DAIGWC010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.143"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(493..1785)
                     /locus_tag="NOB74_002743"
     CDS             complement(493..1785)
                     /locus_tag="NOB74_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI1221869.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(2059..2319)
                     /locus_tag="NOB74_002744"
     CDS             complement(2059..2319)
                     /locus_tag="NOB74_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221870.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          886 a          483 c          398 g          851 t
ORIGIN      
        1 ttatattata aattcacatg attatcgaat tttattaagt tagtttttct tgtaaatctc
       61 tgttcccaat gaaactcgag acacttattt taaagaggaa acaatgtggt atttaaatag
      121 ccctcttgta tgggctactc tgtgatactt attagccatt aaactatttt acccacatag
      181 catatatttt gaaatcgttc attccgtaaa ttcaactaaa tatgcctaaa aaaataaaaa
      241 atctaagata gaataagatt tattcagtct tagatggatt tatagcaact ttttcgtaac
      301 aactttaaaa aatacgaaaa gaaagagctg ttttactctg actacgttgc taaattgtcg
      361 tttaatcatt catttaaacc aaatcttttt ttatagaatt cgttttaatc ctcctgaatc
      421 caaaaactat gaaaaccgta attaaatagt taagagtttt taaccaccat aattctctcg
      481 gctattttga aatcagataa attttgatcg gacacatagt tgaataaacc taccgttgtt
      541 acggaaggta aatcgcatac ttttcattct agaggagaag gtctcgttga tcattaactg
      601 attaagcacc atagcccagt tttgaattcg accacctgac cacttcgcgt gtaattcttt
      661 cgtgcgtaaa taaagtagtt ttaggagtgc attctcatta gagaacgctc ctttttttgt
      721 gacttttctg aagctggagt ggacactttc aaccgcattg gtagtgtaca taatttttcg
      781 aatggcacta ccataatcaa atagttgttc aacatgtgca aagttccgtt tccagacatc
      841 tacagcacca gaataatgag accaccgatt ttgaaaactg tcaaaagcag catgtgcagc
      901 gtttagagaa gaagcaccgt agaacttttt catatctcgg cagacttcct tatagtcctt
      961 acttggaata tagcgcaatg catttcgaac aagatgaaca atacagcgct gaacaattac
     1021 cgatggaaag atcgcttttg cgccttcttc gaggccagaa acaccgtcca tcgaaatgaa
     1081 aaagacatct tcgacaccac gtgctttcag ttcatcaaat acttgcatcc agcgattttt
     1141 agattctgtt tgatttaacc ataatcctaa aatctcctta tttcctttga gatcatagcc
     1201 aagaatggtg tatacagcat attctttggc ttcataattt tctcgtaaag taacatacat
     1261 acaatcaacg aatagaaagg cataacactt tgctaggggg cgggcttgcc attcttccaa
     1321 ttcaggaagg acagcgtcag tgatatctga aatcatttca tgggaaatat caaagccata
     1381 aatagcttcg acggttgcgg caatatctcg ttgactcatt cctcgtgcat acatggaaag
     1441 aaccttccct tcgatgtcgg agacatctcg ttttctctta ggaattaact ctggttcaaa
     1501 ggaagcttcc cggtctctag gaacatcaat agctacttca ccaaaactgg ttttaagcgt
     1561 tttagttcca tagccatttc gacggttatc gtgttcctta ggctctttag aatgggcatc
     1621 ataacctaaa tgattattca attctccttg aagcattttt tcaaaaaggg gcccaaacac
     1681 atctttcaaa gcatcttgca tgtcatcgac agattcaggt tgataggcat tcagaatgga
     1741 ttcagctaac ttttcggcat caggatttct tttctttcta gccatcgtgt aatcacctct
     1801 tgatcttatt gtagaaaaag aaaaaccgcg aagcaaccac ctgcctagga ttaatggtta
     1861 cttacacggt ttatattaca ctctcatcat taaaaaagta tctttcgata ttactaaaca
     1921 atgaaattat ctatttgaaa tttaaatctg ataatatatt gagtgttcca atgagggctt
     1981 tgatcctatt atccatatct ttttcagttt taatattgat acacattata agaaaaagaa
     2041 acttttggtt aatttatttc atcccagtgc aaaatataaa aaagtaaaat agaccatagg
     2101 caatagatta acaattaata taatacaagc aaatattcta ttcattgtat ttctgctttc
     2161 aaaaagttct aatattgaaa gtataattcc acaaatgcct ataataagta tgggaataag
     2221 attagaaaat aacaccccga gccaatctgt gaaaattact atatttacta atatccctat
     2281 taacatacct atcatattta ttaaatcaat ttttttcatt agatatttct cctttattaa
     2341 atctgaagta cttatattaa aataattcta aactatttac ctcaaaaagt gcaataaatt
     2401 atttctgaac aataaaatga tagtcaaaac aaaaaaatat tgttaatcgt tcagagccat
     2461 ccgagagtgt aaaatatttt gtgtaaatga aaaaatccat acaaaaaagg aaggcgcttc
     2521 tgtagaataa agttaacgac aaccaattca cagaaaagag gacttcccta tgaatgattt
     2581 tactacagaa attgtgcaaa ctctagtcac taaaggcg
//
LOCUS       DAIGWC010000140         2400 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.144, whole genome shotgun sequence.
ACCESSION   DAIGWC010000140 DAIGWC010000000
VERSION     DAIGWC010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.144"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            207..2069
                     /locus_tag="NOB74_002745"
     CDS             207..2069
                     /locus_tag="NOB74_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1221871.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2400
                     /locus_tag="NOB74_002746"
     CDS             2069..>2400
                     /locus_tag="NOB74_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1221872.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
//
LOCUS       DAIGWC010000141         2359 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.146, whole genome shotgun sequence.
ACCESSION   DAIGWC010000141 DAIGWC010000000
VERSION     DAIGWC010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.146"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            56..2209
                     /locus_tag="NOB74_002747"
     CDS             56..2209
                     /locus_tag="NOB74_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCI1221873.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          811 a          416 c          528 g          604 t
ORIGIN      
        1 taagaagttt ttgggtacaa tgaagcatga atgtaaatag gcggaaggat aggaaatgat
       61 gaaagatttt atgaaaaaaa tattaaatac ttcttggtta gaaaaaataa gaaaaggtgc
      121 acaagaacct aagaacaaaa cgtttcgccg gtcccatgtt ccttttcgct taaattttct
      181 ttttttcatt atatttacgt tatttgttgc gttgattgct agattgggtt atttgcagat
      241 cgtgaacggc gaagagatgg aggcgcgagt gaagtctact tctacgatta cggtccaaga
      301 aagtactcct cgcggaatga tctacgactc cacaggaaaa gctttagtta cgaataaagc
      361 gaatcaggcc atcacatata cgagaggaac acaagttacg gctaaagatt tgcttgaaat
      421 cgcaacgaag ctgaactcgc tgatcgatgt tccggtagat gaaaatctga cagatagaga
      481 taaaaaagat ttttggctgg ctgatcccaa acatttgaaa gaagccacaa aaagactttc
      541 ggcaaaagaa aagcaattag ggaacagcga acaatatagt gcgatggtca ataaagtcac
      601 agctgatgag attaatttaa acgaggagca attaaaaatt gctaccatct ttaaacggat
      661 gaatagtgca tatgaattaa acactgtcta tatcaaaaac tctggtgtta ctgatcaaga
      721 gttagctgtt gtggcagaac gcgcttctga acttccagga gtttcgactg gcacagactg
      781 gacacgagaa tataatgcag caagttcact gaaaagtatt cttggcagtg tgacgactga
      841 aaagcaagga cttccagcag atgaagcaga gaaataccta gcaaaaggtt attctcggaa
      901 tgaccgtgta ggacaaagtt atttggaaaa acaatatgaa gatgtcctgc aaggaaccaa
      961 aacccaatat gaagtttccc ttgataatga aggaaatgtt tcgaatcaaa aagaaatctt
     1021 ctctggggaa aaaggttcta atttaatgtt atctatgaat gcagaattcc aatcaaaagt
     1081 agaagaaatt ttgaaaagga attatcaaac attgatcaac aacggcaaag cacagtattc
     1141 gcctggtgct tatgcagtgg ctatgaatcc tcagacagga gaagtgctag caatgactgg
     1201 tttcagtcat gaacaaggtt ccaaagaaat caccgagaat gctttaggca cgattactag
     1261 cgcctttgat ccagggtctg tagtcaaggc tggtactttg acagcaggct gggcaagtaa
     1321 cgcgatcagc ggaaatcaag ttttgattga tgagccgatt cgtctgcaag gtgcttcaga
     1381 aaaaagctct gtctttaatc gaagcggaca agttgctctt gatgcagtca aagcatcgga
     1441 attgtcttct aatacgtata tgatcaaagt ggcgttaaag atgttaggac tagactatac
     1501 acctggaatg ggactaccta gtttagatga agaagctaaa gcttatcagc aattgagaga
     1561 ctctttcaaa gagtttggtc ttggtacaac gactgggatc gatttgccga atgaatctcc
     1621 tgggatctca cgttctgttg attatatgaa gaagttcaat gcggataatg gcaaagaatg
     1681 gtatgctcca ggtaacttta ccgatttggc atttggacag tttgacacat atacaccaat
     1741 ccaattagct caatatgctt caacagtcgc taatggcggg aaacgagtac agccgcacct
     1801 agtcaaagcg atctatggca atgacgaaaa tggaaacttg ggtgaagtga agaaagaaat
     1861 tggcacaaca gtagaaaata cggtcaatat ttctgcagaa aatatggcga tcctccgtga
     1921 aggattccac caagttgtcc atggtaccga tccttacaca acagccaaac cattagccag
     1981 tgcgaaaatg gacctttccg caaaaacagg gactgcagaa acggttgcgg aaggtcatcc
     2041 agatattgcg acagtcaata gtaatatcgt ggcatacgga ccaacagaca atccggaaat
     2101 tgccatcagt gttgtcttgc cgaacttatt agacgaacaa gaccacataa acttgacgat
     2161 tgctaaagaa ataatggacg cgtattatga tatgttcatg gcaaaataaa aaagaggtcg
     2221 tgaaaaagcc gcttagtttc gagtatgaag aaaaattttg tgaaaatagc ttctcacatt
     2281 tttgcttaaa tttgacttca taccgagaaa ctggcttttg aacaccgttt actcggcaaa
     2341 aaaggttgtg acaaaaatt
//
LOCUS       DAIGWC010000142         2244 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.147, whole genome shotgun sequence.
ACCESSION   DAIGWC010000142 DAIGWC010000000
VERSION     DAIGWC010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.147"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(365..1156)
                     /gene="msrA"
                     /locus_tag="NOB74_002748"
     CDS             complement(365..1156)
                     /gene="msrA"
                     /locus_tag="NOB74_002748"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI1221874.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
     gene            complement(1347..1982)
                     /locus_tag="NOB74_002749"
     CDS             complement(1347..1982)
                     /locus_tag="NOB74_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCI1221875.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
BASE COUNT          730 a          459 c          346 g          709 t
ORIGIN      
        1 tagttattgt ttgcgctttt atacggaatt tagttcatca ttaatgtgga attcgattag
       61 gtgtctatta attatcaaga tgattctcta caaaattcca tagaaaaatc aagattctac
      121 aattcgaatt ctctttcaca tggaaataaa ggctagtaaa aaaacaggag ttgtgacaaa
      181 agacttgtca tacctcctgt ttccttgcga cttgaagctg aatgctttgc gccacaacct
      241 tttcctcggt gttctcaaag caactcctcg aaataattca taactgtcca aaaatatgaa
      301 aagctatttt tgtcagttgc tcattatttt gtcggagctg aacgctttgc gccacaacct
      361 tcctctatct atgtcgctga aaaaataaat gaagctgatg cgaatgcttg atctttttat
      421 atcttttagg ttgcttctga taaaattgtt gatgatgatt ttcagctggc caaaaagtct
      481 ttgcttggcg aatctctgta acgataggac ggctaaatcg gttagattga atcagttgtt
      541 ctcttgattt ttcagccaat tgcctttgct tttcattaac aacaaataga attgaacgat
      601 attgtttccc ccgatcttga aattgaccaa aggcatctgt agggtctgaa atttgccaat
      661 aaatctccaa cagctcttca taggttattt gacgtgtatc aaatatgatc tcaacagctt
      721 caacatgccc agtatatcca ccactgactt gatcgtaatt tggttttttg gtctctccac
      781 ctgtataacc agataacact gagattacac ctggttttgt ttcaaaaggc tcaaccatac
      841 accagaaaca gccaccggca aaaatcgccc gttcttggta taagggtgaa gttatcttat
      901 gtttggcata atcataagcc tttgcactcg ctgactcccc tgtgattctt aaataaaaat
      961 ccatcgcatc tggtgtcaaa ttatctcgta gtgctagcgg acgcaagttg acctctagtt
     1021 tttctatcac ctgctttatc gacatttttg ctaggtcttc ttttgcctct tcaaattgtg
     1081 ttctttccca ttctcttgta tttcgattta aaataatatt ataaaggtct atttccatct
     1141 gctccacatc taacatgaag tcaccctctt tcaagttttc ttcttattca ttcaaaaaat
     1201 gactacctga aatttagcac aacgcataac aagttaagac taacttgctt ttcgctctcc
     1261 tcatctctat tcttagtcga acacatccac acgaatggtt acccatagag aaattctttt
     1321 acttaatcag cttcacactg ctttttctac tttcgtagtt gaaaaaaact taaacaaatc
     1381 atcggcaaat agttaaagaa aaaacttaag cgttgaaaga agcccaattg cttaaagaag
     1441 gcaaactgac taatcgacgg aatccgtgct aatccgtaaa gacctgcaat tagtaaacta
     1501 ataactgtta aaacaagata aaaatggcta agcgtacctt gaccactttg acgataaagc
     1561 agaacaagta acaatgggaa aagtagaaag cctgcatagc ctagcccaga acctatatta
     1621 tggatccaag tcgatagatt ccaagagctt tcattcgtat tgatactgaa taacccagta
     1681 aaaatacaat cacctatccc atataaacca actgttgcaa cagcaagtat tgcaagtgtt
     1741 tttgatgttc caataaatag gtgatacaac gcaggcaacg aaagaacaaa aaaaagtcca
     1801 gatacaactg accagaccaa gaaagcacgt ctgactggac tatctacgtc accaaacaca
     1861 ctaattacgg tagtcatttg attcagtttg ggataaaaaa ggccaaggat atacggtgtc
     1921 gataaatcac taatcacacc taataataaa aaataaaaac catatttttg caaaaaaatc
     1981 attttcttct cctacttttt agtgattatt cgatacatcc aacaatcaaa ttttttctca
     2041 ttttaacaca tatttttatt ctagttgcct tttgaacaat caataacata aaggtgagtt
     2101 tcttctacat tttaaaaaat cgaatggcac tgaagagttc agttgtcagc atcaatctcc
     2161 tactcaaaaa ggcaaaaaaa cgtaagtcag atgttgttga catctcactt acgcatccat
     2221 tgattgaaaa tttcttagta aaat
//
LOCUS       DAIGWC010000143         2125 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.148, whole genome shotgun sequence.
ACCESSION   DAIGWC010000143 DAIGWC010000000
VERSION     DAIGWC010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.148"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..159
                     /locus_tag="NOB74_002750"
     CDS             <1..159
                     /locus_tag="NOB74_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI1221876.1"
                     /translation="RRNKFYRSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGIPA"
     gene            242..859
                     /locus_tag="NOB74_002751"
     CDS             242..859
                     /locus_tag="NOB74_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221877.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
     gene            1023..1355
                     /locus_tag="NOB74_002752"
     CDS             1023..1355
                     /locus_tag="NOB74_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221878.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
     gene            1679..1840
                     /locus_tag="NOB74_002753"
     CDS             1679..1840
                     /locus_tag="NOB74_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCI1221879.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
     gene            1872..2125
                     /locus_tag="NOB74_002754"
                     /pseudo
     CDS             1872..2125
                     /locus_tag="NOB74_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          758 a          272 c          429 g          666 t
ORIGIN      
        1 cgacggaata aattttatcg aagtctccgg actgcctcat ccacgattaa ggggatggag
       61 accattcgag gaatatataa aaagaaccga agaaatggaa cgctcttcgg cttttcggtg
      121 tctactgaga tcaaggtatt aatgggaata ccagcctaag atatttggag ttcagagagg
      181 gcgcgtttga ttttcaaact tcgcaacaga accattattt taaagtggga ggaaaattgt
      241 tttgtggata tttaaacaag aaatctttgc taaattattt agtttagatg gattaggttg
      301 gggaatctta ttttttattt ttttattttt aggatctatg tggatctggt ttgttgataa
      361 aaaaaattct tatgagaaag taatagtgaa aaaaatgaat cgaaatgaat tcgatgattt
      421 ttcaaaggaa catagagttg aattgtacga tagtcatgaa attaacagta cttctccatc
      481 ttattattgg gtatttggtt gcgaagaaaa accattggag attaaattgt tgaaaatgct
      541 tgaaaatcct ccagtcattg aagatttttc tgcaaaaaac gttgaaaaac agatgtttga
      601 acaggtacaa ataagaggtc aaaacaaaat ttcattagaa ccagatgaat atgcagcctt
      661 ttttttagaa acaaattcag gtacttcaat gcctgttttc aaagttaaat taaaaatgaa
      721 tggtcgttta tgcacttatg atcttgttgc aaatatgcgc tatggttcta ctggtgatag
      781 acgtactatt ttaaaatttg agcaaacctt tagaagtttt ttgaaaaata gagtatccca
      841 aatttttaat ttggattgaa aaaattaaaa atttggccaa aaatactaca gttttttaga
      901 gcaatcatct tatgatgatt gctctttttt tgttgttttt gtgtcattcg ttgttcaaat
      961 cctctattcg taaaataaat attttaaact agaaatatgc cttattttta ggaggaatca
     1021 aaatgaacaa tagagaaata ttggcaaaag aaatggcgga tttgaaagca aaagaagcga
     1081 agattagagc gaaacgaaaa cagattagac agaaagaaat gatttcttta gcgaaattat
     1141 attgtaaaaa ggaaggcttt aagacacctg ctgaagcatt agattttttg gaatcaaata
     1201 aaagaaatca ttcagtaaat gatgaggttt tagtatcgct aagaaaattt gcagatggat
     1261 tagtttggca agaaaatggt gcatattggc gtacgaatga tgttaagggt ttgactcaat
     1321 ttatggcaca atttcgttca gaaaatgtga actaaattga ggaggggttg aagtgaaaag
     1381 caatactttt cacttttggt tttttgcgga ataaaaattg tgaaaacaat gacgcaaaaa
     1441 gccaatggtt ttgaacgaaa aaaggacgta aaaaaggaat gcgaaggcag tcgtttttcg
     1501 ttcgcttttt cgtttgagag aaacggagtt tctcatcggc tgttaagccg atatagccct
     1561 cggcagagct tacagacttt acgcagtata agtctagtaa gttatacctt acatggaggt
     1621 ttttccgaat ttagcttgtg attctcgcaa taattttaac gaaaggaagt acacagttat
     1681 ggcctatatg gtggcacgaa cacaaaagca taaagttggg tcgttaaatg gacttcaaaa
     1741 tcatgtagat cgtaaaacga aaaatcatac gaataaagac attgatatta cgaaaagtgg
     1801 ttctgttgca aagttttcca aaaaatctat tttagtgtaa aattgagaaa aaagacagag
     1861 aggatagagt aatgaatcat tttaaaggca aacaattcaa aaaatgacgt cattattgtc
     1921 gctgttagtt actacctgcg ttacaatcta agctatcgtg aagttcagga attgttatat
     1981 gatcgtggaa taaatgtttg tcatactacg atttatcgtt gggtgcaaga gtacagcaaa
     2041 gtcctcgatt atctttggaa gaagaaaaat agacaatcct tctattcatg gaaaatggac
     2101 gaaacctata tcaaaattaa gggac
//
LOCUS       DAIGWC010000144         2056 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.149, whole genome shotgun sequence.
ACCESSION   DAIGWC010000144 DAIGWC010000000
VERSION     DAIGWC010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.149"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            493..714
                     /locus_tag="NOB74_002755"
     CDS             493..714
                     /locus_tag="NOB74_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221880.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="NOB74_002756"
     CDS             715..972
                     /locus_tag="NOB74_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221881.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKVAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="NOB74_002757"
     CDS             complement(1108..1710)
                     /locus_tag="NOB74_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI1221882.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKLRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="NOB74_002758"
     CDS             complement(1777..1932)
                     /locus_tag="NOB74_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1221883.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          462 c          314 g          602 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggtggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaag cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatta ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DAIGWC010000145         2004 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.150, whole genome shotgun sequence.
ACCESSION   DAIGWC010000145 DAIGWC010000000
VERSION     DAIGWC010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.150"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..378
                     /locus_tag="NOB74_002759"
     CDS             <1..378
                     /locus_tag="NOB74_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HCI1221884.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="NOB74_002760"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="NOB74_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCI1221885.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2004
                     /locus_tag="NOB74_002761"
     CDS             1859..>2004
                     /locus_tag="NOB74_002761"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221886.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFT"
BASE COUNT          555 a          340 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt ttac
//
LOCUS       DAIGWC010000146         1982 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.151, whole genome shotgun sequence.
ACCESSION   DAIGWC010000146 DAIGWC010000000
VERSION     DAIGWC010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1982
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.151"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..810)
                     /locus_tag="NOB74_002762"
     CDS             complement(<1..810)
                     /locus_tag="NOB74_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI1221887.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDK"
     gene            complement(1370..1573)
                     /locus_tag="NOB74_002763"
     CDS             complement(1370..1573)
                     /locus_tag="NOB74_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221888.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSVKEGFTLGFSISFKKGTKN
                     TSISHNNRELTDSQKINGLSGRK"
     gene            complement(1773..>1982)
                     /locus_tag="NOB74_002764"
     CDS             complement(1773..>1982)
                     /locus_tag="NOB74_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI1221889.1"
                     /translation="KIVIDGLIAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRE
                     TFKESADELKKELDTWLLGLDVTEK"
BASE COUNT          559 a          459 c          308 g          656 t
ORIGIN      
        1 tttatcaata ggttttatat caatcggcaa aaaatgcggg cttgcaaaac tatctaagct
       61 ttcctgaacc atcgcatgcc aatccgttgc tttgccacgt cttagctgca tttctaaccg
      121 ccaccacgta tcgatttctt ttggcacgat tacttttttt cgttcctgct ctagcttttt
      181 gttgtacagt cgcacttggc gctcactggc acgactgccc cagtacgctg tttctagctt
      241 gccagaacgg ccgtagattg gcttaaaaga aatcgggtct acaatacgat actgagtaat
      301 aaagtcatcc ggcacatcta caatatcgca ggcaatatcc gcccgggaaa aatgcggatc
      361 taaaaatagg tcatgaatga atcctttcat ggaactagct aaaaactggc ctatcttatt
      421 cggattaaaa tcaatacgac cttttccttc atgaaattta agtatttcga tatacgcaat
      481 atcttctcca tattgatcga ataattgcca gccgtttatc ccaactgatt tcaaatatcc
      541 ctgattttcg ttcaaacgca ttaattgctc gaaatcgaca aaaacaactc catttttcgt
      601 ccaataagct atggtatcat tcagttttcc gacaattgta attcgatcaa tcgaccaatt
      661 taattttagg ggggtggtcg taccttgcac acttaaccgc ctgttagaaa tacggttaag
      721 tttttcgagc tgatttatcg ttgttctttt ttctgcccct cgaccttcaa tttttgattg
      781 aatttcactc aactgatttt catttgccat tttcgtcctc caaacgaaaa aagagacttt
      841 tggaaagaat ttccagagtt cacgtaaccc taaaaattca tatccaaaaa tctctagctt
      901 gaagaaacct aaaaatattc gtataatgaa cctgagttac ggagctaggt gaagtagttt
      961 ccgtaaatag tcgagagtgt tagcgcactg ctcggctttt attttgctct tttttctcgt
     1021 tttctttgat tatagcactc ctcctaaaaa aataaaaaga cctcagggaa tttcattccc
     1081 cgaacccctt gagcctcctc ctgccgaaat ggaaagggcg cacccgctgt ttatttcatt
     1141 cagctatcgg ttttcacaat ctaacacgat cgttccgcta ccagtcgcct tacaggctcc
     1201 attttcgctc ctctaacgtg ttttaacgat tgtgccgata actaaacgaa ataaacgcta
     1261 aaaccgctca gaacgcaaaa tatgccattt tagagctatt gtagaaaatg tagtttgaaa
     1321 tgcaattttc ttctttcagc tttttatttc ccacttgtaa atctgctaat tattttctac
     1381 cagacaaacc attgattttt tggctatcag ttaactcacg attattatga gaaatgcttg
     1441 tattctttgt tccctttttg aacgaaatac taaaccctaa ggtgaacccc tccttcacgc
     1501 tgtcgctaat aaaaagagtg taaacctttc tgttactctt tgacaaagag taacattttc
     1561 ctaattgtga catggctgtc acaattccaa atgctctccg agggtattcg ctgtcacaag
     1621 tgacaacgaa aaaaggagcc gaaagcgtgt cacgctctca actcctttta cgctttattt
     1681 tgcttcacgc aaaataatcg cttatcgtaa atccacgtca ctaaacattg acgtaaattt
     1741 actctcactc atctgacttt tcttattcgg tatcacttct ctgtcacatc caaccccaaa
     1801 agccacgtat ccaattcttt ttttaattcg tctgcagatt ccttaaaagt ctctcgtaaa
     1861 tgattcgtta actcatcatt ttgactttct tgcttcagca aattccgata tttatatttt
     1921 gtatgtctag caattatcga ccaattagaa ggctcagcta tcaaaccatc aataactatt
     1981 tt
//
LOCUS       DAIGWC010000147         1751 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.152, whole genome shotgun sequence.
ACCESSION   DAIGWC010000147 DAIGWC010000000
VERSION     DAIGWC010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.152"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            136..309
                     /locus_tag="NOB74_002765"
     CDS             136..309
                     /locus_tag="NOB74_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221890.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            949..1422
                     /locus_tag="NOB74_002766"
     CDS             949..1422
                     /locus_tag="NOB74_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HCI1221891.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="NOB74_002767"
     CDS             1431..1658
                     /locus_tag="NOB74_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1221892.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          588 a          272 c          260 g          631 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaaaa atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt t
//
LOCUS       DAIGWC010000148         1665 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.154, whole genome shotgun sequence.
ACCESSION   DAIGWC010000148 DAIGWC010000000
VERSION     DAIGWC010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.154"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            132..506
                     /locus_tag="NOB74_002768"
     CDS             132..506
                     /locus_tag="NOB74_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI1221893.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="NOB74_002769"
     CDS             complement(620..1249)
                     /locus_tag="NOB74_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI1221894.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="NOB74_002770"
     tRNA            complement(1383..1455)
                     /locus_tag="NOB74_002770"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          558 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tactt
//
LOCUS       DAIGWC010000149         1656 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.155, whole genome shotgun sequence.
ACCESSION   DAIGWC010000149 DAIGWC010000000
VERSION     DAIGWC010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.155"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(101..586)
                     /gene="vanZ"
                     /locus_tag="NOB74_002771"
     CDS             complement(101..586)
                     /gene="vanZ"
                     /locus_tag="NOB74_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HCI1221895.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(739..1650)
                     /locus_tag="NOB74_002772"
     CDS             complement(739..1650)
                     /locus_tag="NOB74_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HCI1221896.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT          532 a          317 c          224 g          583 t
ORIGIN      
        1 acacctacgg gcgagtttcc ccacatcccg ttttccatct aatccaattc attcaatatc
       61 tttatgtgta tgaaagatca gattgcttga tttagacatc ttacacgtaa tttattctta
      121 aatgggtacg gtaaacgagc aataatacga gcaaaagtat acctacaaaa ataataactc
      181 tgtctaattt tttttgattc atatgcttat tgcttaaacc atataatttc agtccaagaa
      241 agcctccaac agtatttgta attacatctg ttatgtctgt cgctccaata gcgaagataa
      301 attgaattat ttcaaaagta agacttaaaa ccagtacaaa agcaaactta ggtaaaaatc
      361 cgatttcttt aaaattgaca ttcaaaagca agccaaatgg aataaagatt ataacattat
      421 ctatcatctc tctgaaattc ccagtagcag taaatggagt caagttaaga cttctttgat
      481 gataattaaa tactgataaa atattgtatt gtaatttgaa taacactaac cagattagtg
      541 tcactaaata taaagctagc aatcctctag ataatatttt tcccaatata atttcctcta
      601 attcttttgt ttaagttgta tcattagtat agcaatgtcc tagttaacgt gggttttaaa
      661 ttaaaaagct aacgttaccc caaaagtgct agtacaataa tgctgttcat taatttcgtt
      721 ggtttcattc cgccatcctt acctccttga attagtatgt gttgatccgg gaaacactgt
      781 cacaattaca ccgtctatat tgtttcctga tatctcataa cgaagattag tcggcacatg
      841 aatggtggta tttttagtaa caggataata aaagatctca tatttttccc catttacact
      901 aacagaaatg gttttttctt cttttaggta atccatatat tcctcgagaa cgaaattctt
      961 ttctttcata atcgcactat gtggtaaacc aacatagcga atatgccatg gttcatattg
     1021 aattcctgtt aactctgttt tgtcctctgg ataacgtaaa atgaacccgt atttccaagc
     1081 attttcttct atccactttc cttcaggggc tcgttccatt ttcgtcaagc ttgatcctac
     1141 atctagtgat aaacctgaat tatgctcact ataacctgct ggtaaggcat actcagcccc
     1201 catttcttgg taaagcacac tttgctcatc aaagtctcga tagccactat taataataaa
     1261 atgactaacg ccacccttta cagcatcatt gaccatctct gaaaattttt gtgctatttc
     1321 ttttgacata taaatattac tatcaagcaa cccgtatcca tttattaatt cgtcatgttt
     1381 agataaattc acgatatctg acttcacact ttcttggcga acaggatatt tactattgat
     1441 taatagcaga tttccttgat aaacctgttc ttctgtaatt gttttctctt gggtattttc
     1501 agaagtccca ctattttcta aatgttcttt gggattttga tcataatttt gaaattcgac
     1561 tttttcctga gaaaacagtg cttcattaac gtagtcataa cctaagtata ttaagaataa
     1621 caataacaat aaaaaaaaca acttcttcat tttcag
//
LOCUS       DAIGWC010000150         1452 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.156, whole genome shotgun sequence.
ACCESSION   DAIGWC010000150 DAIGWC010000000
VERSION     DAIGWC010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1452
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.156"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            24..248
                     /locus_tag="NOB74_002773"
     CDS             24..248
                     /locus_tag="NOB74_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCI1221897.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            245..1270
                     /locus_tag="NOB74_002774"
     CDS             245..1270
                     /locus_tag="NOB74_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI1221898.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
BASE COUNT          482 a          246 c          302 g          422 t
ORIGIN      
        1 actttattta gggagagaag aaaatgaata ataaaacgtt cgaagtacta aaatggttcg
       61 cactggtaat tattcccgca ctagctactt tcgtggggtt agttggtaaa gcgctcaatt
      121 ggcagtacac agatatctgt gttgtcatca ttactggttt tggcgcgttt ttagggagtg
      181 tgttgggtgt atcaaatcga acctacaaaa tgttctcggc tgaaagcgaa gaaggaggaa
      241 acaaatgaaa aagaaaatta ctattactgc gatgagcctg ttaacggctc tttttttatt
      301 acccattaat acgtttgctt atactattaa tgacgagtat aatttagcgc cgaatcaagg
      361 agactccaga ttagcaattc ctaacaaaat tattttgcac gaaactggaa tagatgcacc
      421 agcaagaaac gtagccgcca acatgaaaaa taattataac ggaagcaatt cttatactac
      481 agatgttatt ggtgacggtg ggattgttta ccgtgtgggt gagcaaggat atgtttcgtg
      541 gggagctggt aacgctaatc cttatgcgcc tgtacagatt gaattacagc gcacatatga
      601 taaagcattg tttgaaaaaa actatcgagc ttatattgaa tatacaagag atagtgcaaa
      661 aaaatatgga attccattga ctcttgatca aggaacttct ttatttacaa aaggaatcat
      721 ttctcatttg tgggtgacaa attatgtttg ggggaaccac acagatccat atggttactt
      781 atcgcaaatg ggagttagca aagaaaagct tgcttatgat ttagctcatg gatttaccga
      841 tgaaaatcca acaacttctg aaaacaagcc tgtcattgat ccaacacgag ctggtgcagc
      901 taatcctacg ctgacagatg gaacaaatca cgcccacatt gatcagtttg gggaaatcga
      961 aaacgcaaac ttgcatgtgg ctggatggca cattgctaac tataaatacg agtatatttt
     1021 cattatggac tacaatactg ggaaagaatt agctcgagta agagctgatg gaatttatag
     1081 accagatgta aaccaagctt ataatacttc tggaaatgtt ggttatcatg tatctttcaa
     1141 tatgcgtaat tttcctagta agaaagtcta tgtaatgatg cgggcaacga atgatccaga
     1201 gggaaacact aaaggcggtg cgcaagattt ccatgacaaa cgttggtatt taaatattcc
     1261 taaacgataa aaatagctcc tcgttgagga gcagtacata actatattga caactataaa
     1321 aattattcga taaaatagtg atgttatcgc atatcttcac tatcacccat aaatagtcac
     1381 actccaagct atgcgataac aggtttgttg ccacacattc tactggttga ttgtttatgg
     1441 ctttatgtgg ca
//
LOCUS       DAIGWC010000151         1424 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.157, whole genome shotgun sequence.
ACCESSION   DAIGWC010000151 DAIGWC010000000
VERSION     DAIGWC010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.157"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(150..1337)
                     /locus_tag="NOB74_002775"
     CDS             complement(150..1337)
                     /locus_tag="NOB74_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HCI1221899.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAIGWC010000152         1407 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.158, whole genome shotgun sequence.
ACCESSION   DAIGWC010000152 DAIGWC010000000
VERSION     DAIGWC010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.158"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(48..419)
                     /locus_tag="NOB74_002776"
     CDS             complement(48..419)
                     /locus_tag="NOB74_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221900.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(421..822)
                     /locus_tag="NOB74_002777"
     CDS             complement(421..822)
                     /locus_tag="NOB74_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221901.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            complement(836..1243)
                     /locus_tag="NOB74_002778"
     CDS             complement(836..1243)
                     /locus_tag="NOB74_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221902.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
BASE COUNT          453 a          241 c          176 g          537 t
ORIGIN      
        1 tacaaagatt aaataaaaaa ataacaaaca aactcgcttg aaattcatta ggtgagtttg
       61 tttattattt tttctgcttc tcgattcatc agcgccatat ctgttttcgt aatggtttca
      121 ttaggaatat agtcagcaca ttttcttttc tctaacattc tatacccact attatgtatt
      181 cctaaggtat tcaattcctt aactgttgaa aacaaattcc aaacggtttg gtggcttcct
      241 tttccgctac ttccattata aataatatca taattttctt tcaaatactc atcagatttt
      301 ttaaaagcac tgtagtatgc tcttgaaaca gcagttcttc tataagattc tttagaatta
      361 tatttatcat ctgattcaat ttgtttggaa atagataaat attcattaaa gtcaaacatt
      421 ttattccccc aaagttgcta ctacagattt ccccatatat ttatagtcag ataatacatt
      481 atcgagagta tccaaaacat cgtaatctga ggaaaacaat tcagatgttg ttttgataac
      541 aaagaaatac aagtttaaat cttcatcata ttttatattg atttcagctt ttctttttaa
      601 aaccgtattt atcacatcaa aaattttgcc atcattactt gaaattgtgt taatctcatt
      661 ttttgtagta attacaagtt gattatcatt tttagttttc ggagtagaac ttgcatccac
      721 aacaactgga gatgctagaa ttaccgatgc gcaagcaaaa atcgcagcaa aatttattaa
      781 gctaccactc cgatgtgtat ttgatggtac tatatcaagc atccgtatcg tctccttaat
      841 ttttttccac tggtttgttg accttgatat caaagatttg ccttccaatc tcagttccat
      901 taaatttaac aacagcataa tgctctcctg cttcttcaac caagacattt ctggcgttta
      961 tattaaagtt tatatcgtta acttgaggag gcaagcttac cgatacttca cccgtagaaa
     1021 aaatttgttt ttcattcttg tttaaaactt caatttctac tatttttatc ttttctgtat
     1081 cctctatctc agacaccaca gctgttacag aaaatgataa agcagtagga attaaaggcg
     1141 cattaataga aagagctgga ttaattactt tattaataac attagtgcca aattgctgac
     1201 tttctacatc ttctgaaatt attaattgta ctctataaga cattgatttc tcctaatttt
     1261 tacatttatt taataaattt atgtttcact tttgctagtc aatttagttt aacaatagta
     1321 acaaagcttt gtcaacggaa atattagcta attttgtaag catatttata agtatatttg
     1381 taagcatatc tgacatttaa tcagtag
//
LOCUS       DAIGWC010000153         1368 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.159, whole genome shotgun sequence.
ACCESSION   DAIGWC010000153 DAIGWC010000000
VERSION     DAIGWC010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.159"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            117..800
                     /locus_tag="NOB74_002779"
     CDS             117..800
                     /locus_tag="NOB74_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221903.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIK
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
     gene            complement(837..1334)
                     /locus_tag="NOB74_002780"
     CDS             complement(837..1334)
                     /locus_tag="NOB74_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1221904.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT          431 a          239 c          230 g          468 t
ORIGIN      
        1 attttttcct agaggaaaat gtctaaacat gttggtaaat caacaaaaaa acgcatatag
       61 tagtctcaaa actcccaaga aatgaggact atttaacaaa ctacgatggt tacgtcgtga
      121 caactgaaca ttttgactta gccaatcctg ttactaaagt cgatgatatc cccgattatg
      181 aaatgtacag tcaaacaatc gatagcttaa ataagcgttt tggcaatcgt gttttaaaag
      241 gcatcaaaat cggttacatc gcttctgaaa aggatcggat catcgactat ttagccgata
      301 aagattacga tttaaaatta ctcagtgtgc atcataatgg gcaatttgat tatttagatg
      361 acgaagtcaa agatatggat cctgctattg tgattcctca gtattttgca caactttcag
      421 aagcactagt tgttatagaa gcagatgtct ttgctcattt tgactatggt tttcgggtat
      481 ttggtctatc cgttgctgaa tttaaacaat atgaagcgca gtttttaccg attctagatc
      541 aagtaatcaa aaataaattg gcattcgaat taaatgctaa gagcgcttac ttgtatgaca
      601 atttagcgtt atatgaatat gtcatcgatt tatatctttc acgtggtggt accttgttta
      661 gtgttggatc agatgggcat taccttgaac atttccgttt ccatttcgat gatctttttg
      721 ctctgttaaa agcaaatggt gtgacggaat tagcgattta tcaaaaagga aagcgaatta
      781 tggttccatt accagtctaa aaaaacgtcc tcagcatcaa aagtgaggac gtttttttag
      841 atttcttttt ctaaaatcgg acaaatacga tcttgttttc ctaaaggaaa atgtttgatc
      901 ccgatttttt taaatccatg acgttcataa aaacgaatac ctgcatgatt tttttcataa
      961 acagtcaaac gtaaataacg tttttgtttc gttttagcat aacgattcgc ttcatcgagt
     1021 aaccgttgcc ctaacccttt gttttgataa tctttgagca gatagagccg ttgaatctct
     1081 atagcatctt tttcatcatt gactttcata taaccaatga gtatttgatg atccttaata
     1141 ccaataaatt tactggttga ctgtgccaat tctactgcca atatttcagt tgtcaattgt
     1201 gtctgtaaat atccttgcat atcaagtgga tctgcgccat cgataaacga ttcataaaaa
     1261 ctgacaacac ttacaacttg taaagcatct agatcatcat aatctaaata cgctagtgtg
     1321 atttgattgt tcatctaact cctccttttg acatagtata ctataaat
//
LOCUS       DAIGWC010000154         1343 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.160, whole genome shotgun sequence.
ACCESSION   DAIGWC010000154 DAIGWC010000000
VERSION     DAIGWC010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.160"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            48..1343
                     /locus_tag="NOB74_002781"
     CDS             48..1343
                     /locus_tag="NOB74_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI1221905.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          421 a          266 c          256 g          400 t
ORIGIN      
        1 aaatccttta gaattaattt ggctaccaat tcataggagg attcaagatg tctcatactc
       61 agcttatcaa agatacccta aatattctag acctaaatat ctatttcgag gaaaattgtt
      121 taactaaaga aaaatacaaa gggcaaattt gcttgattta caaaggaact cttctgtaca
      181 agccagaaga gtgttcccat tgtctttgtg tcgtcccctc taggatcatt cgttggggga
      241 cgacaaccgt tcggttgtta ctgaatgatg tgtctgagta tcgcacttat ctggagctga
      301 agaaacaacg atttaaatgt aagtcttgcc aaagaacatt cgtagcggat acctctgttg
      361 ctgaaaaaca ctgtttcatt agtcaaaaag ttcgttggtc tgtcattgct cgcttaaaag
      421 agaatacttc catgacggaa atcgctcgtc agaaaaatat ttccacttct tcggtctatc
      481 gtgtcatgaa gcgattctac cgcccattga atcctttcaa acagactttg ccaaaggtct
      541 tatgctttga tgaattcaaa tcggttcgaa gtgttgccag tgcaatgagt tttatcatga
      601 tggacggaca aagccatgca ttattggata ttgtcgaaaa tcgacgcttg ccttatttag
      661 aacgctattt ttctcggttt tcattagcga ctcgtgaagc cgttcaattg attgttattg
      721 atatgtatgc gccttatgtt tcgttggtga aaaagctttt cccgaatgct cagttgatca
      781 tcgatcgttt ccacatcgtc caacatattg gcagaacttt cttgaatcat cgagtgaaag
      841 aaaccacggt acgacttaaa ggaaattccc actctcaacg agggttaggg aaaaaattga
      901 agcgctattg gaaactccta caaaaagaag aagcaaagtt aaactatgaa aaacgggttt
      961 ggcgtgccag ttttaaagat tatttgactg aaagtgagat tgccgatcga ctgttagctg
     1021 cttgtcccaa cttacgccaa ggctatcagt tataccaaga cattctttat gcggtaaaga
     1081 aaagagatca gtcactattt gaggattgtt taactagaga cattagcggt ctgccagaaa
     1141 cctatacaac cactttacga acgtttaaaa agtttctgcc acagatccaa aatgcgcttc
     1201 actacagcta ttcaaacgga ccattggaat gcttaaacaa ccacatcaaa gtattaaaac
     1261 gcaatgcgta cggctttcgc aacttttaca atttcaaact acgaattatg attcgtcatg
     1321 gcaaaacatt tttaaccaaa taa
//
LOCUS       DAIGWC010000155         1334 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.161, whole genome shotgun sequence.
ACCESSION   DAIGWC010000155 DAIGWC010000000
VERSION     DAIGWC010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.161"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            86..1165
                     /locus_tag="NOB74_002782"
     CDS             86..1165
                     /locus_tag="NOB74_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1221906.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
BASE COUNT          359 a          357 c          369 g          249 t
ORIGIN      
        1 agccatttgg aaataaaaaa acgccacgtg aattccatgt tatattgaag ttaccacaac
       61 tctcaataga caaggatgaa ttcacatgac gcaaaaccat gataacacag tttcacgcaa
      121 gggaaaacac ctaacctact cagaacgttg ccaaatcgcc atcctgaaaa aggaaaacta
      181 ttccaaccgt caggttgcgg atgtcctggg ctgcgtgccg cagaccataa acaacgaaat
      241 caaacgcggg accgttactc agcttaaccg ccagaatcag aacgggaagg tctacgacta
      301 ttatcatgac gtctacgacg ccgatgccgg gcaggcggcc tacgagaaga accgcttgaa
      361 ctgcggcaga cggcccttat gggccgacac ggacgccttc attgaatggg cggacgacat
      421 gatgctgttg gaaaaatggt ccccggacgt ggtggtgggc tttgccagaa aacacgaatt
      481 gttcgacccg gccattatcc ctgggaccac caccctctat cagtggatcg accgtggcat
      541 catgaaaacg aagaatatgg acctgctaga aaaactgtcc cgcaaaccga aatcgtcccg
      601 tcatggcaac cgcccgaata aacgggtgct agggaaatcc attgaagagc gcccggaggc
      661 ggttggtacc cggaaaacct tcggccattg ggaagtcgac acggtcgtag gaaacaagac
      721 caagtcggat gccgtgctgc tgacgttggt ggaacggcag acacgcttcg aggtcattct
      781 gaagctggcc gggaaggatg ccgaatcggt caaccaagcg gtccgacagc tgagagaacg
      841 ggctggtgcg tacttcggcc agctgttcaa gacggttacc tcggacaacg gctcggagtt
      901 cgcgggactg cacgatgcct tgcaggatgt ggcaaacatc tacttcagcc acccctatgc
      961 ttcctgggag cgcgggacga gcgaaaacca acacaagctg attcgccgtt tcatccccaa
     1021 gggcagccca atcggcaacg tgagcgaaaa ccaaatcttg cggattcagc gttggatgaa
     1081 cgattacccg cgaaagattt tgggctatgc aacgccgcat gacacgttcg tccaggcatt
     1141 taggcaggaa cggttgacgg cttgacacgt gggcccttga caacgagcct ccctcggcat
     1201 ggcttgtgtc tggaaagctg gccggggcca gccagtcggg agactaccat gcctcagctc
     1261 attgtcaagg gcccactcga ttagaaaaat tagacggttg gtggtaacga gcaaccgggt
     1321 caccatgggt ggct
//
LOCUS       DAIGWC010000156         1294 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.162, whole genome shotgun sequence.
ACCESSION   DAIGWC010000156 DAIGWC010000000
VERSION     DAIGWC010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.162"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..1244
                     /locus_tag="NOB74_002783"
     CDS             <1..1244
                     /locus_tag="NOB74_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HCI1221907.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DAIGWC010000157         1247 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.163, whole genome shotgun sequence.
ACCESSION   DAIGWC010000157 DAIGWC010000000
VERSION     DAIGWC010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.163"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            200..742
                     /locus_tag="NOB74_002784"
     CDS             200..742
                     /locus_tag="NOB74_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221908.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1247
                     /locus_tag="NOB74_002785"
     CDS             898..>1247
                     /locus_tag="NOB74_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HCI1221909.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          515 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccaga
//
LOCUS       DAIGWC010000158         1231 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.164, whole genome shotgun sequence.
ACCESSION   DAIGWC010000158 DAIGWC010000000
VERSION     DAIGWC010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.164"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..>1231
                     /locus_tag="NOB74_002786"
     rRNA            <1..>1231
                     /locus_tag="NOB74_002786"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          323 a          280 c          375 g          253 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc c
//
LOCUS       DAIGWC010000159         1214 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.165, whole genome shotgun sequence.
ACCESSION   DAIGWC010000159 DAIGWC010000000
VERSION     DAIGWC010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1214
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.165"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            70..1026
                     /locus_tag="NOB74_002787"
     CDS             70..1026
                     /locus_tag="NOB74_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221910.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
     gene            complement(1080..>1214)
                     /locus_tag="NOB74_002788"
     CDS             complement(1080..>1214)
                     /locus_tag="NOB74_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1221911.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
BASE COUNT          427 a          179 c          207 g          401 t
ORIGIN      
        1 ttgacaggga atcctaaaaa cattcggctt tttttatata atctttttaa ctcaacagag
       61 ataagttttg tggaattgta tacgctacct ataattataa aaacagaaaa aatgttaaaa
      121 gatttaaaac agtattatcc tctgtctgct tatgaaaaaa agaaattatt ccacttttta
      181 gcaatcaacc tgttggctga acaagctgat tctttagata ttgctagcaa tcagtcgcta
      241 tttttttcgg atataggatt ttaccactta aaaggagtat taggagaaaa atccgttatt
      301 tttatcaata agacactctc ttggctttat cttcatgata aattggatca aaaatacttg
      361 agaaaaaatg aagatgaaac aatcgaatgg ttgaatgaac gattcattga aagttttgaa
      421 aatcagttta atctgttgcg agaagagacg agccaattga tccgaagaga gttaaccaaa
      481 atacatttta aacttttgca ttacactatt aataaagctg atgaatttcc acttgatgtt
      541 tcttttttta gagaaaacta tccagcattt tattgctatt tgatagagta tataaatgat
      601 ctaacgtcaa aacgcaaaga gttgcttcaa gataaatttt ttcttttttt cagttattta
      661 ttattattga tcaatcacat acccattcaa ctgatttctg aaccagtaaa gatcatcatc
      721 gatttttctt atggtgctgc ctataatcaa tttatcaaga aaaatttaag cttgtacatt
      781 aatctgaaca cggaagtgat agaggcagga aagcctgagt tcccggatgt tataatcacg
      841 aataggaata atctatatga agaaagtgca tctcaagtag tggtttggct cgatccgcca
      901 agagcagtag actgggggaa tcttacaaag attttgttga ctatccaaga agagaaatac
      961 aaagacagca aaattgacaa gcaaatagac gattttcctg aagaaatcat cgacaggatc
     1021 gaatagtgaa cttcttttag aaagtccgac tgctttttct aaaaatatta tttgtcaaat
     1081 taagcgagac aaaactttcc atttacgtaa ctcaaaaaaa cttctaatgg tgtttggtaa
     1141 tttagtgatt ttctagggat atggtttctt ttggacgcaa cggatgagat gaatccttga
     1201 ttgacttggt tgaa
//
LOCUS       DAIGWC010000160         1190 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.166, whole genome shotgun sequence.
ACCESSION   DAIGWC010000160 DAIGWC010000000
VERSION     DAIGWC010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.166"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            143..400
                     /locus_tag="NOB74_002789"
     CDS             143..400
                     /locus_tag="NOB74_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221912.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..1063)
                     /locus_tag="NOB74_002790"
     CDS             complement(632..1063)
                     /locus_tag="NOB74_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HCI1221913.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          147 g          439 t
ORIGIN      
        1 ttttctgtcc acgttcattt tactccaaag ttttcctcat ttcaaaagaa aatcacagaa
       61 tacacgaaga agcgtttcta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt attactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaataa
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacata ccactttgta
      841 taattgtaat tattgctgaa gcaattgaaa caatcaatag taaagacctg tgttcggaag
      901 cctgatcaat taatattggt atactagctg ataagactat ttttataata tttccgatac
      961 caattactct attataaaat cgaatttctt tttttaatct atcgattgta gaatcaatag
     1021 attcgataaa cgctttttga tccatcattt tctctccaat cattttatta aaatcattaa
     1081 caaaaatatt ataataggat ttaagtaagt tctaactaat cacatataaa aataaaaaaa
     1141 catttgtatt ttatcaaagt tttattatac ttgtcaattt gtgtacatcc
//
LOCUS       DAIGWC010000161         1170 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.167, whole genome shotgun sequence.
ACCESSION   DAIGWC010000161 DAIGWC010000000
VERSION     DAIGWC010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.167"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..195
                     /locus_tag="NOB74_002791"
     CDS             <1..195
                     /locus_tag="NOB74_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1221914.1"
                     /translation="ELTLKQMIVLFKEYPSLLRRPILIDEKRILIGFNEDEIRSFVPR
                     EIRCVARNLIYLQNNNILNS"
     gene            209..565
                     /locus_tag="NOB74_002792"
     CDS             209..565
                     /locus_tag="NOB74_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HCI1221915.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          428 a          174 c          210 g          358 t
ORIGIN      
        1 gaattaactt taaagcaaat gatcgtctta ttcaaagaat atccttcatt attgagacga
       61 cctattttga ttgatgaaaa aagaatacta atcggattta atgaagatga gatccggtca
      121 tttgtccctc gtgaaattcg atgtgttgcc agaaatctga tctatttaca aaacaataac
      181 atcttaaatt catagggagg gagccttcgt ggaagtgaaa gtctatggat cagcgcactg
      241 tgtaacaagt ctgaaggcga aacaatggtt agaacaccat caattgcctt atcaatttgt
      301 tgacttagaa gaacgcgatt taagtacaga agaagcagaa gaattatgca gttttgaaga
      361 agtgcaagca gaacagctat ttgcgacttg gtctgaggct tttcacaaca ttgcgattga
      421 cctttcctgt gtaggaaaaa aacaactgat ttttttatgc acacaacata ccaatctcct
      481 cagacgtcct ttgattatta tcgatgaagt tctatttatt ggatacaatg agcagttgat
      541 ggaacagctt atcttaaata aatagacttt aactgtttta atcaagtcac tgagcatttc
      601 atacagttgt aacagtcgaa cacttagcat caagcgtgtt atgtgttctt tttttgactt
      661 tatttttcta ctatagagac atgctcaatt tatgtggtca aaattcaaat ctaggtgggg
      721 atatagagtt aaaaatatat tgacatgtgt aaatttacat gatatattca tttctgttgt
      781 tttaagtagc aaagcaataa aatagtattt taaaaaacat ataaaatagt tgttgacatg
      841 ttagaaatga catgataaga taactgagtt gttaaaaaag aaccacttgt gaagcttgat
      901 tctatcgaaa aaaacttcaa aaaagttctt gacaaataac aaatgataag ttatgataaa
      961 tgagttgctg taagatttcg aaaaacgaaa tcaaaaaaac ttttaaaaaa gagttgacaa
     1021 ttacttgtct ctctgatatg atataaaagt tgctacggca gccaaaaacg aatcggggaa
     1081 cactcctgat gaagtagacc tttgaaaact gaacaaagta agacaaacca aatgtgtagg
     1141 gcgtcttgat tcaattcaag acaacaaaca
//
LOCUS       DAIGWC010000162         1124 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.168, whole genome shotgun sequence.
ACCESSION   DAIGWC010000162 DAIGWC010000000
VERSION     DAIGWC010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.168"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(206..760)
                     /locus_tag="NOB74_002793"
     CDS             complement(206..760)
                     /locus_tag="NOB74_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI1221916.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          362 a          218 c          130 g          414 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatacttcc gaaaattcag ttatcttcat taatctcacc ttctaagttt tcattataca
      181 caaaaaatat atcctaatat ctcaattagc ctcccaattt aaaaccacgt aacgatgccc
      241 ctatttcatc ttcagttata ccaatgtacc tttttgtaat tgcttgcgag ctatgattaa
      301 aaataaacat taaggtagca atgtctctag ttttcttgta gtagtgatac ccaaaagttt
      361 ttcttaatgt atgtgttcct atatcatctc ttcctaattt ttctgctaca tctgcatata
      421 tctgatagac acgatccctt gttatatgtc gaccttgttg ccgacttgga aataaccaat
      481 cattttcttc tttaccttca gtatataata aaatctcttc tctcaaatta tctataaaaa
      541 tcggttttcg cttacctgtt ttatgttcaa caataatagg cttactttta cctcgtatgt
      601 ctccaacttt taatcctata atatctgaca tacgtaaccc attattgatt ccaaacaaaa
      661 ataaaaaact atctctttct ggattacttg ttcttcttag ccaaaactga aaatcttgta
      721 tctcttcatt tgtccttaac ggttgtacat tatagctcac tattgtttcc cttcttaaaa
      781 atattctgag ttcatgatta tatatatatt ttaccataat catgaactta tatatatact
      841 ctgttaaaag tgaagaaaat caaggggttt agtttatgat tttatatcat ttcagtaact
      901 cagaatattc cgactttttt gtacaaaaaa attaacctta cttatatgaa gattctaagc
      961 tcttatttaa attttagacg ggcagttatc cgtagaagtt cttagaatag ctaatttaca
     1021 taattaaatt atatgaaatt taagtttgaa caatatacta agaactcccc ttactataaa
     1081 gtgaaataaa ttagcatatg aataaccgtg ctaccaaact tttc
//
LOCUS       DAIGWC010000163         1091 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.169, whole genome shotgun sequence.
ACCESSION   DAIGWC010000163 DAIGWC010000000
VERSION     DAIGWC010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.169"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="NOB74_002794"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="NOB74_002794"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HCI1221917.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DAIGWC010000164         1035 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.170, whole genome shotgun sequence.
ACCESSION   DAIGWC010000164 DAIGWC010000000
VERSION     DAIGWC010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.170"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..>1035)
                     /locus_tag="NOB74_002795"
     rRNA            complement(<1..>1035)
                     /locus_tag="NOB74_002795"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DAIGWC010000165         1005 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.171, whole genome shotgun sequence.
ACCESSION   DAIGWC010000165 DAIGWC010000000
VERSION     DAIGWC010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.171"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..>1005
                     /locus_tag="NOB74_002796"
     CDS             <1..>1005
                     /locus_tag="NOB74_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI1221918.1"
                     /translation="GKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLVTP
                     FCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPRCL
                     LFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHYIV
                     TDMNAPYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQYR
                     QLKSLFKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQDL
                     LTAYQEKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLENLH
                     "
BASE COUNT          302 a          209 c          191 g          303 t
ORIGIN      
        1 atggcaagaa gatctctatg attctcctga atcgtagcgg taataaacgg acctatcttc
       61 ggttgaagaa acagcgatac ctctgccgag catgtaaaaa atattttacc gctcggacgt
      121 atctcgttac cccattctgc tttatttcta agcagattca ttacaagatc ttagaagaat
      181 tgacagagcg tcaatctata aaagcaattg gtaaacattg cgatgtttct gtgacaactg
      241 ttcagcggac attgtccgcc ttgtcatcag atatccgtca gaatcttgag tatttacctc
      301 ggtgtctatt attcgatgag tttcgttctc tttctacatg gcacggtaaa ttttcttttt
      361 cttgtatgga cggtgagacc gggaaactgt ttgagatctt acctagccgc cgtaaaaaag
      421 atctcgttgc ttttttcatg cgtttttctc tcaaagcgag gttgggtgta cattacatcg
      481 taacggatat gaacgctcct tatttctcac tagttaaaga gtgttttcca aatgcacaag
      541 tgatcgtcga tcggtttcac attgttcaac atctgaaccg cttcttcgat gcggttcgaa
      601 aacgtgtgat gaaaacactt gatcaaaaag acccaataca agctaaacag tatcgccaat
      661 tgaaatcctt attcaaatta cttttaaaat cagaggatcg tttagattac aatacactaa
      721 cgaaaagacg caatttcaat tggagactat tgactgaaac agaagtagtt gaccgccttc
      781 taaagatttc tcctgaactt aaaacagctt atcgttacta ccaagacctg cttactgcgt
      841 atcaggaaaa agatccagat acttttttcc agctgcttcg agcaatgcct ggagaagttc
      901 cattggaact gcaccatatc aaaaaagcct ttttcaaata cgagaaaggg attcggctgg
      961 cattactgaa gaagtattcg aatgcacgac tggaaaatct ccata
//
LOCUS       DAIGWC010000166         1002 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.172, whole genome shotgun sequence.
ACCESSION   DAIGWC010000166 DAIGWC010000000
VERSION     DAIGWC010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.172"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            369..1002
                     /locus_tag="NOB74_002797"
                     /pseudo
     CDS             369..1002
                     /locus_tag="NOB74_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          182 c          183 g          295 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac ct
//
LOCUS       DAIGWC010000167          983 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.173, whole genome shotgun sequence.
ACCESSION   DAIGWC010000167 DAIGWC010000000
VERSION     DAIGWC010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.173"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(34..107)
                     /locus_tag="NOB74_002798"
     tRNA            complement(34..107)
                     /locus_tag="NOB74_002798"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(71..73),aa:Ile,seq:cat)
     gene            complement(662..976)
                     /locus_tag="NOB74_002799"
     CDS             complement(662..976)
                     /locus_tag="NOB74_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221919.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          363 a          154 c          154 g          312 t
ORIGIN      
        1 tctaacacag aacgattcaa ttggctacat taatgtaccc tgtaggactc gaacctacga
       61 ccggacggtt atgagccgtc tgctctgacc aactgagcta agggtagtgg ttgttgccac
      121 ataaagccat aaacaatcaa ccagtagaat gcgtggcaac aaacctgtta tcgcatatct
      181 tggagtgtga ctatttatga gtgatagtga agatatgcgt ctccatatat gtatggttga
      241 gacagataaa catgtatgaa aaacgttgtt aaatcaacgt ttttttattt tggtcaagga
      301 gagaaaagta gagaaataca aaattttttg cattgatttt gcattcaaaa aaacattcaa
      361 acatttagaa atccccaata cgtattcagg aaaatctatt ttaaggttta caaaaagaac
      421 ttttgttcgt acactctttt tgaggtgaac ttttatgctg atggaaggaa aaacacaatt
      481 atggtttaag catgttcctt caaataagtt ttttaattat aaactctaga gaaattaatt
      541 catcctaaca taaaataatt gttcactcaa aagtttttct agaacaatta aaacagcagg
      601 cttcacattc gctatacatt tgtaagaagt aataattcct gtactaaaag gcataattgc
      661 tttaattatt ttttgacttc tcttcaaaca caagaagtag ttgtgtaata attgcagaaa
      721 taaggattcc aataatagat ataaaatttg acatggaaac gtctataaca ttaaaagaat
      781 aaagtgttga agaaagtaaa ctgattgaaa taacccctcc gtaaaaaata gtctgtgaat
      841 atacccactt tttttcagaa gacgtacttc gtttggttct aaaacctatc cctgcatttc
      901 tactcttatc aaaaaaccaa atatttagaa gtaataatat tgctattatt aagataaaat
      961 tactgtaaaa atccaaaagc tat
//
LOCUS       DAIGWC010000168          978 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.174, whole genome shotgun sequence.
ACCESSION   DAIGWC010000168 DAIGWC010000000
VERSION     DAIGWC010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..978
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.174"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            82..>978
                     /locus_tag="NOB74_002800"
     CDS             82..>978
                     /locus_tag="NOB74_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HCI1221920.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYE"
BASE COUNT          333 a          182 c          192 g          271 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaa
//
LOCUS       DAIGWC010000169          903 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.175, whole genome shotgun sequence.
ACCESSION   DAIGWC010000169 DAIGWC010000000
VERSION     DAIGWC010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.175"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
BASE COUNT          349 a          103 c          113 g          338 t
ORIGIN      
        1 attagcaata tataaaagaa ggtatcaaga gtcacagtga atttattccg aaaagtgaaa
       61 agagcaaata taaaatttaa taaaaataag aactaaatag gaaaacgtag acgtaatttt
      121 ctacgttttc cttttcatat atattaaata ttacggaaaa ttatataaac taatttagtg
      181 ttttgtttgt aattcctaat tttgctccac ttttagataa tttttaggtc tatttaactc
      241 attagacatt ctatgctcat ttttctccaa atttgtttca actctttcgt acttaatttt
      301 gcgtatttga aaattcttct tttagagtac ttttattacg atactagtat gatatatatc
      361 tacagcaaac agttaaaatc ttcctaaaat aagcgaatag cattcctaaa acctataaaa
      421 tttttagatg aagcgacaag tggacaatta ataaactact tgaacatgaa attatggatc
      481 acctttcaaa tttagaaaat ggaattctta tacttattgc gcaacattta ttgattgcaa
      541 aattatgtga caaaaagaac tagtagaaga aggaataatg gcttgataat aaagtactac
      601 ctattaaagg tagtacttta tttaatttag tataaattaa catactacta tattttaggt
      661 ttcatattat ataaattaat aatatactac catttgttgg tagtataatt taaaggtaat
      721 aagttattct tttattacta tgtttgggtt ttatagcaaa gaaagtttaa taagagtttg
      781 gacctagcaa acaatattaa tgaggtcatt aaatcttatt atctttagtg atataatgaa
      841 atatctacac gacaaaatta tgatcttgcg taaagttata aaatattaat aaaaatattt
      901 tat
//
LOCUS       DAIGWC010000170          890 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.176, whole genome shotgun sequence.
ACCESSION   DAIGWC010000170 DAIGWC010000000
VERSION     DAIGWC010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.176"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..888
                     /locus_tag="NOB74_002801"
     CDS             <1..888
                     /locus_tag="NOB74_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HCI1221921.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DAIGWC010000171          876 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.177, whole genome shotgun sequence.
ACCESSION   DAIGWC010000171 DAIGWC010000000
VERSION     DAIGWC010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.177"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..434)
                     /locus_tag="NOB74_002802"
     CDS             complement(<1..434)
                     /locus_tag="NOB74_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1221922.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
     gene            complement(451..855)
                     /gene="tnpA"
                     /locus_tag="NOB74_002803"
     CDS             complement(451..855)
                     /gene="tnpA"
                     /locus_tag="NOB74_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HCI1221923.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          263 a          143 c          137 g          333 t
ORIGIN      
        1 tgtctatgaa gcttaattct tactaatgac ttcaatttag gaactttgat gaatttacta
       61 tcaatcaaag caactgtacc attttgatta ttcgttgtat aactctgaac aggatttttc
      121 ttacttttga aacgtggaaa tccaacggat ttatcccgaa aaaaattctt gtatgcttta
      181 tctaaattaa gttgggcatt ggctaaagca aggctatcaa tttctttcaa aaacggaaat
      241 tctttcttgt atttagctgg tgtcggaaaa gtcatttttt tagaagaatc atttttaact
      301 tcttcatacg ccttttttcg gtcatcaagc attagattgt agaccttacg gacacaacca
      361 aaagatttgg caaagaagat ttcttgttcc tctgttggat agattctgaa tttgtatgct
      421 tttagttgtt ccataaagtt cacctacttt ctatttatga ttgtttcctt gattttggat
      481 atacttctta atcacatcaa ttggtgcgcc accagttgtc agaagacaaa aacttttaga
      541 ccagaacatt tctttccaaa gaaattgttt gactcttgga aagtcacgtt ttatcaatct
      601 tgagctggca cttttatagg cattgatgaa ttttgtcaat tctgttttag gttgagcttt
      661 gaacataata tgaacgtggt ctttatcatg attccactcc actaaagtaa tgtgatacga
      721 ttctgaaatt ctttcaaaag tagttttggc ataatcagat atttcatcat caatcacttg
      781 tctacgatat ttcgttacta aaacaaggtg gtaataaaga agaaatactg aatgattatt
      841 tgtatctaat tccatgttat atcaactcat ttcttg
//
LOCUS       DAIGWC010000172          829 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.178, whole genome shotgun sequence.
ACCESSION   DAIGWC010000172 DAIGWC010000000
VERSION     DAIGWC010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.178"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(20..625)
                     /locus_tag="NOB74_002804"
     CDS             complement(20..625)
                     /locus_tag="NOB74_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1221924.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT          257 a          146 c          122 g          304 t
ORIGIN      
        1 gaatgaatgt agtatatttc tacaaatcat tcgctttctt tattttataa atagttggtc
       61 gagagatccc gttttctttt gcaatctctg caactggaat gccttgcttt aacatgtcca
      121 ccacggtttt aaaaactaag cgtttttgcg gatctgttga gttaatagaa tactcgattg
      181 gtcgtccctt atatcggccg gctttttgag ccaataatac tccttgccgc tgacgttcac
      241 gaattttctc acgctcgttt tgtgcaatat aacttagcag tgataaaaac atatcgaaca
      301 tagcggtatc caggagttca tttccagtat taaaatctaa aaactgtgca tctaatattt
      361 ttaacgctac ttttttctgt ttcataaaag caactgtatt ttttatatct tcataatctc
      421 ttcctaaacg atctagtgat gtaacgatga cgcaatcacc ttcacggata taatttagta
      481 atttttgaaa ctcaggacgc tcagtatctt taccactggc tttttcttgg aataatttat
      541 caatgttaag tccttccatc attgccaatt gtcgatccaa attttgatct tgtgaagata
      601 ctcgaatata gccaattttt cccataaaaa actccttttt aaaagtgata taatttacat
      661 gtaaaattta cttgtagttt tactgctatc atagcatttt taaaaataaa ttttatgtag
      721 acttaaaatt tacttcatgg agggtttaaa tggatgaaat caaaagtaac aaaaaagcat
      781 ttggcattta tttaggagaa cctagtacag aacaattaaa ccaattttt
//
LOCUS       DAIGWC010000173          783 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.179, whole genome shotgun sequence.
ACCESSION   DAIGWC010000173 DAIGWC010000000
VERSION     DAIGWC010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.179"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            24..716
                     /locus_tag="NOB74_002805"
     CDS             24..716
                     /locus_tag="NOB74_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HCI1221925.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          281 a          151 c          159 g          192 t
ORIGIN      
        1 tgaaaaaaag gattttagta acaattggtc tagctttttt gttagctggt tgtaccaacg
       61 ggaatgaatc gaaaaaagaa tcaacaaaag aaacagcgaa agcaacagtt gcaactacta
      121 caacaactag cacagagagc aagtcaactg cagcaagtac agaaacagca gatacctcta
      181 cttcgtcaga gtcttccaaa acgactgaaa caactcaaac atctacttca agttcttctg
      241 tagaggcttc atcttcctct tcagaaagca gcgaacaagt tgaacaaaca ctgtggaatg
      301 cagacaaatc cgcacaatta gaggcattta tgaccaaatg gggccaaaca atgggacaac
      361 aatacaaaag ttatacgaat caaatgagtg tggacttata tggtcttaaa gtccctcaag
      421 ctattttgaa cggggagtgg aagatggcta ttggtggagt gcctgtttct gcagaatggt
      481 cagaaagtgg gacaggtcaa gcagactatc aaatcacagc cgtctattcc gatgcagaga
      541 cagaaccata tctgaaaaag cacgtctatc tattcgggtt tcagcaaaat cagccaaaag
      601 tattggtgac acaacaaaat caggggaatc ccgataatta tctttacttc aacgagacag
      661 cgaataatga attgaaaaat ggctttaatc aaatcgttta tggacaagca aattaatgag
      721 ataaacaagg ggttgtgaca tgtcttttat cacaacccct tgctcagttt atttgttagt
      781 ctt
//
LOCUS       DAIGWC010000174          771 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.180, whole genome shotgun sequence.
ACCESSION   DAIGWC010000174 DAIGWC010000000
VERSION     DAIGWC010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.180"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..660
                     /locus_tag="NOB74_002806"
     CDS             <1..660
                     /locus_tag="NOB74_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1221926.1"
                     /translation="YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNK
                     LSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKV
                     DKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          285 a          118 c          143 g          225 t
ORIGIN      
        1 tatatttctt tgttgtgtaa agaagaaatt atcgaattac ctaaaactaa ttccacaatt
       61 ggtattgact taggtattat ggactttgcg attctttctg atggacaaaa aattgataat
      121 aataaattca cgtccaaaat ggaaaagaaa ctaaagcgtg aacaacgcaa attgtctagg
      181 cgtgctttat tggctaaaaa taaaggtacc aatctatttg aagctaaaaa ttatcaaaaa
      241 caaaaacgca aagtagctag attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat gatcaaaaat cacgatatta tctgtattga agacttaaac
      361 acaaaaggta tgttgcgaaa tcataaatta gctaaaagta tttctgatgt ttcttggtca
      421 aagtttgtga ctaaattaca atacaaggct gactggtatg gacgaaaaat catcaaagta
      481 gataaatggt ttccgtctag tcagatttgt tcagagtgcg gacataaaga tggcaagaaa
      541 tctcttgaaa ttcgagaatg gacttgtcct gtttgtcata ctcatcatga tcgtgatatc
      601 aatgctagta tcaatattct gaccgaaggt ctaagactac attctatggg attggcttag
      661 atccaatcat caagaaccgt aggaactacg gggatagctt ggtaaataag agacaccgct
      721 gttagtaaag aaatacgcta tcaagtatgc tctattccca agaagctccc a
//
LOCUS       DAIGWC010000175          758 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.181, whole genome shotgun sequence.
ACCESSION   DAIGWC010000175 DAIGWC010000000
VERSION     DAIGWC010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.181"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            145..576
                     /locus_tag="NOB74_002807"
     CDS             145..576
                     /locus_tag="NOB74_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221927.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            578..715
                     /locus_tag="NOB74_002808"
     CDS             578..715
                     /locus_tag="NOB74_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HCI1221928.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
BASE COUNT          288 a          109 c          154 g          207 t
ORIGIN      
        1 tggttgggtc aatagaccgt tctactttga acagtgctca actatctatt ggcgcagacg
       61 gagccattaa atggagaaga aattcaagtt atggatcagc ttattcattt gttatcactt
      121 attcaattta agggaggaaa tctaatgaaa gtagtttaca aatcaatcaa gccttacgga
      181 ttcgagcaaa tcattttgaa caatcaagaa aatatccctg aaaactgtac agagattaaa
      241 ccaccagttc ctaactggag accaagattt gattttgata aaaaacagtg ggttgagtta
      301 gctactgaag aagagaaaaa agggaatgct gttgatagcg tagatgaatt ggctaatatt
      361 aaggcattat acgaaacgct gaaggcagaa aatgatgaat tgaaacagct aaattctaaa
      421 gcaatgctaa acaatgtagc aatcaagcaa gaaaatgtct tattgaaaga aaagtcagaa
      481 agtttagcgc agttgaattc aaaaacgatg cttgcttctg tacaaaatac caaggaaatc
      541 gaagaaatca aaaaacaatt acaaggtggg aagtaacatg tattcatatg aagatatcaa
      601 actaatgtat gactggggct gtttcactaa cgaacaagta atggttttcg ttccgttgtg
      661 cattactgaa gaaaaagcag ataaaatcat tagcaaagaa gagagcgcat cttaattgat
      721 gtgcttttta ttttgattca aggagttgtc acatgatt
//
LOCUS       DAIGWC010000176          732 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.182, whole genome shotgun sequence.
ACCESSION   DAIGWC010000176 DAIGWC010000000
VERSION     DAIGWC010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.182"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(125..>732)
                     /locus_tag="NOB74_002809"
     CDS             complement(125..>732)
                     /locus_tag="NOB74_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
                     /protein_id="HCI1221929.1"
                     /translation="REVEQLLNAYSSVNDPKTVQTVQALAAEKIRDILDHELPEIDTF
                     LTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVKKLKQPAWNEIDLQE
                     HTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQKTSNVSLFLSTTKA
                     GSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
BASE COUNT          187 a          149 c          126 g          270 t
ORIGIN      
        1 aaggggctgt ccccagactt tagtaggcgt cattagctat ctttcgttag catttaaagg
       61 cgaacaccat cacctattca cttccattaa aagatagcat atttttctgt aaaaaacaat
      121 aaaattatcg ttctttcttt acacgttcag caaattcata gaaaggagcc aatttcgtta
      181 actgttgatt acattggtca ctatcatgac aaatataatt cccctttttc gtatacgtgc
      241 catcagaacc tgctttcgtt gtagaaagaa aaagcgaaac attcgatgtt ttctgacaga
      301 ttgcacagat tcccttattt atcgttggtg ataaagtacc gctaatccct tttaattttt
      361 catcttcgta atagaccatg aattttttct gcgtacctgg atcattccag ccgatgtacg
      421 tatgttcttg caagtcgatt tcattccaag ctggttgttt gagttttttc acttttcgga
      481 ataatttctc gatttgtggt ttgctaggct gcataaacgg ctgaacgatt tgcttcagct
      541 cctccaatgc tctttctgct tgcgcttttg tcagttttac gtctaaaact gtcgttaaaa
      601 atgtatcgat ttctggcagt tcgtgatcta atatgtctcg aatcttttca gctgctagtg
      661 cctgaactgt ttgtaccgtt tttggatcat tgacagatga gtacgcattt aataactgtt
      721 ctacttctct ta
//
LOCUS       DAIGWC010000177          679 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.183, whole genome shotgun sequence.
ACCESSION   DAIGWC010000177 DAIGWC010000000
VERSION     DAIGWC010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.183"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(86..439)
                     /gene="tnpB"
                     /locus_tag="NOB74_002810"
     CDS             complement(86..439)
                     /gene="tnpB"
                     /locus_tag="NOB74_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HCI1221930.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(429..623)
                     /locus_tag="NOB74_002811"
     CDS             complement(429..623)
                     /locus_tag="NOB74_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221931.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          204 a          144 c          115 g          216 t
ORIGIN      
        1 gaatcgaact gattttgtta cagaatacca caagaaacgc acaagaaata ggggttcaac
       61 acattttttg tgttaacccc ccagcttaaa aaactccttt ttttcctggc aaaatagctc
      121 gaggttgatc gatacttaat ccttctaaca accatcgaac ctgttggttc gttaaggttc
      181 gaacttcgtc tttcgtccga ggccatttta acttgccgtt ttctatccgc ttataacaga
      241 gaagaaaacc atcaccgtcc caatagagaa gtttgaaacg gtcttgacgg ttcccgcaaa
      301 ataaaaaaac ggcatcttcg taaagctcga gttgatactc ttgttgaata agactggcaa
      361 gaccatcaat tccttttcgc aaatctgttt ttccgcacac aatataaata tgtttggttt
      421 gaagtaaatc ataaagcatt ggacaacagt tctttcaaaa tagcttgaag aatataattg
      481 ttaataccgt tatagatcaa aacttcagaa ccattctctc ttttgatgcg catcgctaac
      541 ttggcagccg cgggtttacc tttttctggt gcactctttt cgtttcctaa ttggacagga
      601 acaatctcat ttaatttata catagaaaac ctccagactt cttgatagct caagtatatc
      661 ttgaggtgca tttgttagt
//
LOCUS       DAIGWC010000178          606 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.184, whole genome shotgun sequence.
ACCESSION   DAIGWC010000178 DAIGWC010000000
VERSION     DAIGWC010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.184"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            123..>606
                     /locus_tag="NOB74_002812"
     CDS             123..>606
                     /locus_tag="NOB74_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI1221932.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     F"
BASE COUNT          233 a           96 c           96 g          181 t
ORIGIN      
        1 ttttacactc tcataaaaga tagcgtaaaa tattttgtgt aaatagaaat ttagggtaga
       61 aaaaaaagtc cattctgtaa aattaaagtt accacacaga aattttatag gaggactttc
      121 tcatgactaa atttactata gaaattatgc aaacactact caataaaggg gatttagatg
      181 aattatttca ggatcattta gagcgagcga ttaattcact tctacaagca gagctaactg
      241 cttttttaga ttacgaaaaa tatgatcgaa atggattcaa ttcaggaaat tcccgtaacg
      301 ggaattattc acgtacattt aaaacagaat atggcgagtt gaatttaact attcctagag
      361 atcggaatgg cgaattttct caacaaacac taccagcata taagcgaacc aatgattcat
      421 tagaaacgac cattatccaa ttatttcaaa aaggcattac tatggctgaa atctccaaat
      481 taattgaaaa aatgtatggt caccactata cgccacaaac aatctccaac atgagtaaat
      541 tggtggctga agatgtttta gcttttaaag aaagaacgtt agaagccaat tattccgtta
      601 tattta
//
LOCUS       DAIGWC010000179          597 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.185, whole genome shotgun sequence.
ACCESSION   DAIGWC010000179 DAIGWC010000000
VERSION     DAIGWC010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.185"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..480
                     /locus_tag="NOB74_002813"
     CDS             <1..480
                     /locus_tag="NOB74_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI1221933.1"
                     /translation="REIRALEKNIKELDKAIEQVIVVIPEYQCLTSIPGVGKVYAAGL
                     IAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQSQNTPLTKQGNRYFRYYLVEAANSV
                     KNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKFTRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          225 a          114 c          102 g          156 t
ORIGIN      
        1 cgagaaatac gagcacttga aaaaaatatc aaagaattag ataaagccat cgaacaagta
       61 attgttgtca ttccagaata tcaatgctta accagtattc caggcgttgg taaagtctat
      121 gctgccggtt taatcgctga aattggtcaa atcgaaagat ttgaagatca gacaaaattg
      181 gcaaaatacg ctggattaag ttggaaagtg aaccaatctg gaaactatca gtcgcaaaat
      241 acacctctga caaaacaagg aaatcgatat tttagatact acttagttga agctgccaac
      301 tctgtaaaaa attatcttcc tgaatacaaa gctttttatc aaagtaaata taaggaggtt
      361 ccaaagcatc aacacaaacg tgcactcgtc ctaaccgcaa gaaaatttac gcgtctggtg
      421 gatacgctac tacgtaaaca ccaactctat acgccaccaa ggagtgtgat agagaaataa
      481 caatccgtta ttgacgcaaa tccttgaatc aacccgaaaa aaatttgatt ttgatcgggt
      541 ctagtttcgt gcgcttcaaa acatattact caataaagaa aatcttaaat ttcatct
//
LOCUS       DAIGWC010000180          588 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.186, whole genome shotgun sequence.
ACCESSION   DAIGWC010000180 DAIGWC010000000
VERSION     DAIGWC010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.186"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(65..150)
                     /locus_tag="NOB74_002814"
     tRNA            complement(65..150)
                     /locus_tag="NOB74_002814"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Leu,seq:taa)
     gene            complement(167..238)
                     /locus_tag="NOB74_002815"
     tRNA            complement(167..238)
                     /locus_tag="NOB74_002815"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(204..206),aa:Gly,seq:gcc)
     gene            complement(250..322)
                     /locus_tag="NOB74_002816"
     tRNA            complement(250..322)
                     /locus_tag="NOB74_002816"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Thr,seq:tgt)
     gene            complement(340..421)
                     /locus_tag="NOB74_002817"
     tRNA            complement(340..421)
                     /locus_tag="NOB74_002817"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(385..387),aa:Leu,seq:tag)
     gene            complement(429..501)
                     /locus_tag="NOB74_002818"
     tRNA            complement(429..501)
                     /locus_tag="NOB74_002818"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(466..468),aa:Lys,seq:ttt)
     gene            complement(505..577)
                     /locus_tag="NOB74_002819"
     tRNA            complement(505..577)
                     /locus_tag="NOB74_002819"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(542..544),aa:Val,seq:tac)
BASE COUNT          149 a          169 c          138 g          132 t
ORIGIN      
        1 cccctaacct tttgatccgt agtcaaacac tctatccagt tgagctatgg gcgcatattt
       61 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
      121 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      181 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      241 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      301 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      361 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      421 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      481 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      541 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAIGWC010000181          583 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.187, whole genome shotgun sequence.
ACCESSION   DAIGWC010000181 DAIGWC010000000
VERSION     DAIGWC010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.187"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            87..>583
                     /locus_tag="NOB74_002820"
     CDS             87..>583
                     /locus_tag="NOB74_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HCI1221934.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          221 a          106 c           94 g          162 t
ORIGIN      
        1 taaatgaaaa aatccataca aaaaaggaag tcccttctgt agaataaagt taacgacaac
       61 caattcacag aaaagaggac ttccctatga atgattttac tacagaaatt gtgcaaactc
      121 tagtcactaa aggcgattta aatgaattat tccgttcgca cttagaaaaa gcgataaaca
      181 cactcctacg gactgaatta acggcttttt tagattacga aaaatatgat cgcactggtt
      241 ttaattcagg taattcgaga aacggttctt actttcgatc aatcaaaacc gaatatggtg
      301 aattaacatt ggaaatacct agagatcgta atggtgagtt taaacaacaa actttaccag
      361 cctacaaaag aacaaacgat acattggaaa ccactattat ccatttattc gaaaaaggtg
      421 ttacgatgtc tgaaattgct gatttgatcg aaaaaatgta cggtcatcac tatactccac
      481 aaaccatgtc caacatgact aaagttctga ctgaagaagt aaatgccttt aaatccagag
      541 ccttaaatga taagtatgtc gctattttta tggacgctac tta
//
LOCUS       DAIGWC010000182          575 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.188, whole genome shotgun sequence.
ACCESSION   DAIGWC010000182 DAIGWC010000000
VERSION     DAIGWC010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.188"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..>575
                     /locus_tag="NOB74_002821"
     rRNA            <1..>575
                     /locus_tag="NOB74_002821"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          183 a          114 c          166 g          112 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatct
//
LOCUS       DAIGWC010000183          566 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.189, whole genome shotgun sequence.
ACCESSION   DAIGWC010000183 DAIGWC010000000
VERSION     DAIGWC010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.189"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..536
                     /locus_tag="NOB74_002822"
     CDS             <1..536
                     /locus_tag="NOB74_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HCI1221935.1"
                     /translation="WVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAI
                     DADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFY
                     QGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTL
                     FGFSVCTEIKVLLGIPA"
BASE COUNT          202 a           99 c          112 g          153 t
ORIGIN      
        1 gttgggtgca agaatatggc aaactactct atcaaatttg gaaaaagaaa aataaaaaat
       61 ccttttattc atggaaaatg gatgaaacgt acatcaaaat taaaggaaaa tggcattatt
      121 tgtatcgagc catcgatgca gatggtttaa ccttggatat ttggttacgt aaaaaacggg
      181 acacacaagc agcctatgct tttcttaagc ggttagtgaa gcagtttgat gaaccgaagg
      241 ttgtagtcac agataaagcc ccctctatta caagtgcctt taagaaacta aaagaatacg
      301 gcttttatca agggacagaa catcgtacca ttaaatacct gaataatttg attgaacaag
      361 accatcgtcc agtaaagaga cgcaataaat tctatcgaag tttacgcact gcctctacca
      421 cgattaaagg catggaagcc attcgaggat tatataagaa aacccgaaaa gaaggcactc
      481 tcttcgggtt ttcggtctgt actgaaatca aggtattatt gggaatccca gcttaaatca
      541 tagataccgt aagggatttt attctt
//
LOCUS       DAIGWC010000184          564 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.190, whole genome shotgun sequence.
ACCESSION   DAIGWC010000184 DAIGWC010000000
VERSION     DAIGWC010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.190"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..>564)
                     /locus_tag="NOB74_002823"
     CDS             complement(<1..>564)
                     /locus_tag="NOB74_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1221936.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQ"
BASE COUNT          160 a          103 c          117 g          184 t
ORIGIN      
        1 cttgtgcaag agcacctagg cggtaactca tggtaattgc acgttgaatt gctttagcga
       61 ttttttctgg ttgcttgaaa cggccttttc ctttttcttg aagtaaatca cagaaagctt
      121 ctaaaggaag ctcagcaagt tcatccaatg tgaaatcttc cgtcatgagt gaaatgaggg
      181 ttgcactaaa aagactcgtc gattcgtctc gcatttctcg agcaagcgta ttacatttgt
      241 acgttagatt ttcaagaaaa tgttgctttg tacgaatcaa ttgcttaata agttgatagc
      301 gagtacgtgt taaacgctgt aaggccatgt atttctcttc tttgataggg gaagttgtga
      361 atcgttgaat acgcaagaaa tcagcgattc ttaatgcatc gtttcgatca gttttattct
      421 catcaaacat gcgactaaat tgtttcaccc gaaaaggatt ttcaatcgtt acaagtgtgt
      481 tgagcttctt tagtttctca tcttcatgaa aaaacatgga aggatggaag ctgtacatgg
      541 acgttgactc catgccaatc acaa
//
LOCUS       DAIGWC010000185          513 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.191, whole genome shotgun sequence.
ACCESSION   DAIGWC010000185 DAIGWC010000000
VERSION     DAIGWC010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.191"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(107..>513)
                     /locus_tag="NOB74_002824"
     CDS             complement(107..>513)
                     /locus_tag="NOB74_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HCI1221937.1"
                     /translation="TPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMNA
                     ASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYEDS
                     QITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          162 a          102 c           78 g          171 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttc
//
LOCUS       DAIGWC010000186          510 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.192, whole genome shotgun sequence.
ACCESSION   DAIGWC010000186 DAIGWC010000000
VERSION     DAIGWC010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.192"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(34..234)
                     /locus_tag="NOB74_002825"
     CDS             complement(34..234)
                     /locus_tag="NOB74_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI1221938.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          169 a           79 c           92 g          170 t
ORIGIN      
        1 aaataacccc tgtatccttt gcggtacagg gggttatttt gtataagtag acattgtagt
       61 ttctaaactg ctatgtccta aacgtttcga tacgctaagt atatttactc cttgataaag
      121 taaaatagat gcatgcgtat gtcttagtcc atcaataaac agtcgaagag aaaataggga
      181 aaaattgatt actaaagaaa aacttactag gtcgacggtg tagttgattt tcatacttca
      241 atagattcga attaaacgat ttcgattggc ttataccagt cctatccaac gaaagatata
      301 tcgttcttaa ctctagcggt ataacttgaa gctttacgta aagccaatgg gaatgaactg
      361 gagatgactt tttattattt ttagtaatag ctgatgggtt aatacttaca actttccttt
      421 tcaaagtacc atataaaaaa acggtggggt tgtttagcga aataaaggat ctaagccaat
      481 agcttagatc ctttattcta tgctttatat
//
LOCUS       DAIGWC010000187          506 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.193, whole genome shotgun sequence.
ACCESSION   DAIGWC010000187 DAIGWC010000000
VERSION     DAIGWC010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.193"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..>506
                     /locus_tag="NOB74_002826"
     CDS             <1..>506
                     /locus_tag="NOB74_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1221939.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFS"
BASE COUNT          167 a           89 c          103 g          147 t
ORIGIN      
        1 caaatcaaac tgtggtagac gtccgcttgt tttacccgag gaacaatcag aatatattca
       61 aagaaaggtt gttcaaggat ggacacccga tgtgattgtt ggtcgtgcag cgtttcctat
      121 tagttgttct gctcgtacca tttatcgtat gttcaaaaag gggctatttg attcttctga
      181 cttaccgatg aaaggcaagc gtaaaccgaa tggacatcaa gaaagacgtg gaaaacaaac
      241 tttccgccgc tctattcatg aacgtgaaaa ggattatagc caattctcaa atgagtttgg
      301 tcaccttgaa ggtgacacta tcgtaggtct gaaacataaa agtgctgtaa ttaccttagt
      361 tgaacgatta tcaaaagtta tcatcacatt gaaaccgtgt ggtagacaag cgattgatat
      421 tgaaaaaaaa ttaaatcaat ggtttgaatc tgtaccgaaa aacctattca aatccatcac
      481 ttttgattgt ggaaaggaat tttcaa
//
LOCUS       DAIGWC010000188          504 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.194, whole genome shotgun sequence.
ACCESSION   DAIGWC010000188 DAIGWC010000000
VERSION     DAIGWC010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.194"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
BASE COUNT          226 a           70 c           81 g          127 t
ORIGIN      
        1 ccttaggcag cttttgctgt gtagaaagga ataaataata acgaaagttc aaaagctaat
       61 gccgactatt ctagacatta aagaagacga aaacgaacga taaagaaaga aaagttatga
      121 ataatcgttt attgaaaaaa acttgaaaaa atacaaaaaa ttcgttgacc aagctaaatt
      181 tagttggtat attattactt gtccaaaaga cagaagaaaa tatttattca aaaacataac
      241 aaaaaagtta ttgacatgtt actaacgaca tgataagata actgagtcgt taaaaaagaa
      301 ccacttgcga agcttgattc tatcgaaaaa aacttcaaaa aagttcttga caaataacaa
      361 acgataagtt atgataaatg agttgccgaa agatttcgaa aaacgaaatc gaaaaaaact
      421 tttaaaaaag agttgacaat cgcttgtctc tctgatatga tataaaagtt gctacggcag
      481 ccaaaaatga atcgggaaac actc
//
LOCUS       DAIGWC010000189          482 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.195, whole genome shotgun sequence.
ACCESSION   DAIGWC010000189 DAIGWC010000000
VERSION     DAIGWC010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.195"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..>482
                     /locus_tag="NOB74_002827"
     CDS             <1..>482
                     /locus_tag="NOB74_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI1221940.1"
                     /translation="FPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSP
                     LCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVK
                     VLETLSEEANLPNILGDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQ
                     "
BASE COUNT          173 a           95 c           78 g          136 t
ORIGIN      
        1 ctttcctagt aggagtcgat tcactcgctt aagttcaaac ttagcttaca ctatcaagat
       61 tattcgatac tttttcatca agaagctcac caaaggtgaa ctagtcggaa ttatagatag
      121 ttttcctagt ccattatgta aaccagttag aaatagacaa gcaaaactat tgaatcaaat
      181 agccaaagtt ggctataact caacaaaaaa atcttatttt tatggtctta aaattcatat
      241 gatcgttact aagactggct ttccgattac ttactcaatc acgaatccag gtgtccatga
      301 cgtgaaagtg ttagagactt tatcggaaga agcgaatctt cccaatatcc taggggacaa
      361 aggatatatt agccataaaa tccatgaaaa gcttgccctt aagggcatta ctatatccgt
      421 tccgccacgt aaaaacatgg ataaatcaga aaaactagac cacagcttac ttggaaaaca
      481 aa
//
LOCUS       DAIGWC010000190          470 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.196, whole genome shotgun sequence.
ACCESSION   DAIGWC010000190 DAIGWC010000000
VERSION     DAIGWC010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.196"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..>470
                     /locus_tag="NOB74_002828"
     CDS             <1..>470
                     /locus_tag="NOB74_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HCI1221941.1"
                     /translation="ALSKRGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKT
                     TNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLV
                     KKAFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAV"
BASE COUNT          167 a           78 c           88 g          137 t
ORIGIN      
        1 aagccttatc aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa
       61 atagaggatt aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca
      121 atgaagccaa aacgacaaac gtattgaatc gtaaattctt aagagacaac ccattagaag
      181 cgatcgtaac agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca
      241 ttttggatct gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg
      301 ttctagtaaa aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc
      361 atactgatcg tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg
      421 acatcaatcg atcattgagt cataaaggct gtccttttga taatgccgta
//
LOCUS       DAIGWC010000191          451 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.197, whole genome shotgun sequence.
ACCESSION   DAIGWC010000191 DAIGWC010000000
VERSION     DAIGWC010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.197"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..>451)
                     /locus_tag="NOB74_002829"
     CDS             complement(<1..>451)
                     /locus_tag="NOB74_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1221942.1"
                     /translation="QDQMLAFSTVTREGYREYKSNPKECVNCPLLNQCTISKNHQRVI
                     TRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVAT
                     HTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQARVTSL"
BASE COUNT          109 a          101 c           80 g          161 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat gactcgttga tgatttttac ttatggtaca ttggtttagc
      361 agaggacagt tcacacattc ttttggattg gatttgtatt ctcggtaccc ttctcgagta
      421 accgttgaaa aagcgagcat ttgatcttgc g
//
LOCUS       DAIGWC010000192          444 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.198, whole genome shotgun sequence.
ACCESSION   DAIGWC010000192 DAIGWC010000000
VERSION     DAIGWC010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.198"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
BASE COUNT          187 a           61 c           73 g          123 t
ORIGIN      
        1 aaataatcat tattatcaaa ataatgttaa aaataaaaaa gaattgtcca tcactgttat
       61 tcaaatcatt ttatcaaaac tacatagtaa atgttaaaaa gcaacatgac ataatatata
      121 gaaggcttta cagtatatat gggagcttac taaaaaagaa tggagtaaga gttaacacaa
      181 tgggccatta gctgaagttt taagcacttc aaggtatgaa acagaatggc ctgtaatact
      241 acatgattat ttagactgct caaactgcta tcagtctggt ggaatgaata aagtattata
      301 ctaaaagcag atccaactac aacgtaacag gaaaccagtt gtatcaggaa aagtgatagt
      361 acatggagaa gaaaaggccc cctttgtatg agtcagtaca tatcttattt atagataaaa
      421 cggtattcaa tcgaaataaa aaat
//
LOCUS       DAIGWC010000193          440 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.199, whole genome shotgun sequence.
ACCESSION   DAIGWC010000193 DAIGWC010000000
VERSION     DAIGWC010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.199"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            11..>440
                     /locus_tag="NOB74_002830"
     CDS             11..>440
                     /locus_tag="NOB74_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI1221943.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          168 a           57 c           88 g          127 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag
//
LOCUS       DAIGWC010000194          421 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.200, whole genome shotgun sequence.
ACCESSION   DAIGWC010000194 DAIGWC010000000
VERSION     DAIGWC010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.200"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..390
                     /locus_tag="NOB74_002831"
     CDS             <1..390
                     /locus_tag="NOB74_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1221944.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          163 a           74 c           65 g          119 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggagga caatttattt
      421 a
//
LOCUS       DAIGWC010000195          415 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.201, whole genome shotgun sequence.
ACCESSION   DAIGWC010000195 DAIGWC010000000
VERSION     DAIGWC010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.201"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(1..222)
                     /locus_tag="NOB74_002832"
                     /pseudo
     CDS             complement(1..222)
                     /locus_tag="NOB74_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          164 a           68 c           56 g          127 t
ORIGIN      
        1 tcagtcacga tatcaaacaa aaagtataca cccttcttca ttctagtttt cgcagcagga
       61 attttgaaat agttccttat tagaatagta gagattgatt aataagctat cttcgattgc
      121 taaaaagaaa acttctgaat tccatacttt ataaaaatct ttgataaatc tattcgaagg
      181 gtcaaattta aaccataatt gtgtttttcc ttccatcagc ataaaagttc acctcaaaaa
      241 gagtatacga acgaatgttc tttttgtgaa ggcggaattt aatatactga ataatagaaa
      301 acaagtactt gtgccaaatt atgtgccaaa aaaattcgaa ttcaacaaaa tgtaaacaaa
      361 tagaaaacct tctatattaa gatttcctgc aataacaaac acaacagaag acgtg
//
LOCUS       DAIGWC010000196          367 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.202, whole genome shotgun sequence.
ACCESSION   DAIGWC010000196 DAIGWC010000000
VERSION     DAIGWC010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.202"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..>367
                     /locus_tag="NOB74_002833"
     CDS             <1..>367
                     /locus_tag="NOB74_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1221945.1"
                     /translation="KIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNL
                     YLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKL
                     KERKISKADPESGYYVKGER"
BASE COUNT          137 a           61 c           80 g           89 t
ORIGIN      
        1 aaaatccccc atttctcaac ttttggaaag aattatgttc gccgatttag agaaacgacg
       61 gtgtttgagg atatttttgc ctatatttta gaacaagcag ttaaagcagg ttttgtaaca
      121 gaggataatt tgtatctgga ttctacccac atcaaagcta acgccaataa acataagttt
      181 acgaaagaaa tgacccatga tgaagcgaaa gcctatcagg atgaattaga agatgagatc
      241 aatcgtcaac gaatagaggc tggaaaacgc ccttttactt tggacttaga aaaggaagtg
      301 aagctgaaag aaagaaaaat aagtaaagct gatccggaaa gcggctacta cgtcaaaggc
      361 gaacgag
//
LOCUS       DAIGWC010000197          325 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.203, whole genome shotgun sequence.
ACCESSION   DAIGWC010000197 DAIGWC010000000
VERSION     DAIGWC010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.203"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..>325
                     /locus_tag="NOB74_002834"
     rRNA            <1..>325
                     /locus_tag="NOB74_002834"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           98 a           63 c           94 g           70 t
ORIGIN      
        1 cgaacccacg tacgttgaaa agtgcgggga tgaggtgtgg gtagcggaga aattccaaac
       61 gaacttggag atagctggtt ctctccgaaa tagctttagg gctagcctcg gaattgagaa
      121 tgatggaggt agagcactgt ttggactagg ggcccatctc gggttaccga attcagataa
      181 actccgaatg ccattcattc atatccggga gtcagactgt gagtgataag atccatagtc
      241 gaaagggaaa cagcccagac caccagctaa ggtcccaaaa tatatgttaa gtggaaaagg
      301 atgtggggtt gcacagacaa ctagg
//
LOCUS       DAIGWC010000198          318 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.204, whole genome shotgun sequence.
ACCESSION   DAIGWC010000198 DAIGWC010000000
VERSION     DAIGWC010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.204"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            1..318
                     /locus_tag="NOB74_002835"
                     /pseudo
     CDS             1..318
                     /locus_tag="NOB74_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT           93 a           65 c           54 g          106 t
ORIGIN      
        1 ccatacttaa tgcgacgaca atggatttat tcttagcaca atcatcactc ctagaaatat
       61 tcatgacagt caagtcgcct ttcagctcat caaacaatcg aagagacttt ttcctgaaat
      121 caattgtgtt gtcgctgatg ctgagtataa gacacctaag tttgttcact ttttgactca
      181 tttaaacctt cgaccttgtt tgccttattc aaggcccaaa gggaaaaagg ggctattatc
      241 aaaaaatgag tttctctatg acgagtattt tgattgttat atttgtccgc aagatcaaat
      301 gctcgctttt tcaacggt
//
LOCUS       DAIGWC010000199          299 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.205, whole genome shotgun sequence.
ACCESSION   DAIGWC010000199 DAIGWC010000000
VERSION     DAIGWC010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.205"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..>299
                     /locus_tag="NOB74_002836"
     CDS             <1..>299
                     /locus_tag="NOB74_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1221946.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT          102 a           63 c           54 g           80 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaaga
//
LOCUS       DAIGWC010000200          299 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.206, whole genome shotgun sequence.
ACCESSION   DAIGWC010000200 DAIGWC010000000
VERSION     DAIGWC010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.206"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
BASE COUNT          106 a           33 c           46 g          114 t
ORIGIN      
        1 gactacctgt attagtcctc ttttttgacc agattttgac cagtctattt tacattctaa
       61 tatattcata tgagctaatt ttatgattaa atggtaagtt tttccttgtt tgttttagtt
      121 taaactagtg tgtaattcaa aaatctatat ggaaggatct gtggggtaaa tcattataca
      181 aaagtaaaat tttacttatt aacaggctgt agaaatataa aaaagaacta aaatttaact
      241 aaattatgtg ctattcttaa ggaaagccaa gtgtatgaga aagtttctga gaatataat
//
LOCUS       DAIGWC010000201          296 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.207, whole genome shotgun sequence.
ACCESSION   DAIGWC010000201 DAIGWC010000000
VERSION     DAIGWC010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.207"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
BASE COUNT          105 a           51 c           43 g           97 t
ORIGIN      
        1 tctataattt ctaggactga tggaaatttt ctatctgtcc tagttttttt gtaaaaaaac
       61 aaaaagacat acaaaatttc cggtagaata gagtctccta caacatcatt ctgggggaat
      121 tcttgtatgt ccatgaatca ttttatcaaa caactcttta ctattaaaga ctcaaatatc
      181 caaattcaat cctttgaaga aactttttat aaaagcagaa aaagtatcgt tattgaggga
      241 actctgatcc gtacctacag acgttgtccg tgttgtaaag attctacaaa gcaaat
//
LOCUS       DAIGWC010000202          292 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.208, whole genome shotgun sequence.
ACCESSION   DAIGWC010000202 DAIGWC010000000
VERSION     DAIGWC010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.208"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            <1..185
                     /locus_tag="NOB74_002837"
     CDS             <1..185
                     /locus_tag="NOB74_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI1221947.1"
                     /translation="YTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQ
                     RILDNELGCANASEAV"
BASE COUNT           83 a           63 c           69 g           77 t
ORIGIN      
        1 aatacacatt tgaaacctta caacaattgg atttggagtt atttgactat gtcaattggt
       61 ggaaccacct tcggttgcac ggtacacttg gctacgagac accggttggt taccgtaacc
      121 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
      181 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggaggc tcattgtcaa
      241 ggacaatcgg aatagcatac ggaaagaagt tctgcacctt ataaaatttg tc
//
LOCUS       DAIGWC010000203          281 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.209, whole genome shotgun sequence.
ACCESSION   DAIGWC010000203 DAIGWC010000000
VERSION     DAIGWC010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.209"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            28..>281
                     /locus_tag="NOB74_002838"
     CDS             28..>281
                     /locus_tag="NOB74_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1221948.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDT"
BASE COUNT           84 a           53 c           56 g           88 t
ORIGIN      
        1 tgaaaacgaa tgcaaggagt gatagctatg atgtctaaaa acaatacgaa tggtagaaat
       61 caatttgcga tgcttacgat tgatgatcta gttcctcaag atcatctcgt tcgaaagatt
      121 gatgccgcgc ttgattttga atttatttat ccaatcgtcg aagccactta ctccgattta
      181 ggtcgcccaa gtatcgatcc agtgattctg atcaaattgg tgtttattca gtatttattc
      241 ggtatccgtt ccatgcgaca aaccattaag gaagtcgata c
//
LOCUS       DAIGWC010000204          266 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.210, whole genome shotgun sequence.
ACCESSION   DAIGWC010000204 DAIGWC010000000
VERSION     DAIGWC010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.210"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            82..>266
                     /locus_tag="NOB74_002839"
     CDS             82..>266
                     /locus_tag="NOB74_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI1221949.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVV"
BASE COUNT           93 a           40 c           54 g           79 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagt
//
LOCUS       DAIGWC010000205          265 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.211, whole genome shotgun sequence.
ACCESSION   DAIGWC010000205 DAIGWC010000000
VERSION     DAIGWC010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.211"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(34..>265)
                     /locus_tag="NOB74_002840"
     CDS             complement(34..>265)
                     /locus_tag="NOB74_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1221950.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           77 a           39 c           47 g          102 t
ORIGIN      
        1 agaaggactg accttctgtc tcagattttt ttgttatttc acttgaatca attgattgat
       61 caaaaaaatc ctgattttca tgttctcaaa tgatttaaat ccataagata atcgtttcag
      121 tgtcttgata tggggaatct tggcctctat tttgccatta gaatacgggt aaatcatagc
      181 attgtaaata ccttcttcat acgttaaaag gttttgaagt ttcgtgcgaa gttgtgcatc
      241 aagtgtttca ggaagatttt ttaat
//
LOCUS       DAIGWC010000206          241 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.212, whole genome shotgun sequence.
ACCESSION   DAIGWC010000206 DAIGWC010000000
VERSION     DAIGWC010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.212"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..220)
                     /locus_tag="NOB74_002841"
     CDS             complement(<1..220)
                     /locus_tag="NOB74_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1221951.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFP"
BASE COUNT           63 a           45 c           46 g           87 t
ORIGIN      
        1 caggaaaaat gatttcggtt ctcccacaac gtcgcttatt ttctttgtat tgttcaaagt
       61 attcaagtgc tgttccacca catttgagaa agttatagac attgtaaatt gtttggcgtc
      121 cacgtttaag ctgcttcgca acgatagcaa ccggagtttc ttgatgaaaa tatgcttcta
      181 tcattacaag ctcgtttggt gtaagatggg tataagtcat ttatgttcac tctccttgta
      241 t
//
LOCUS       DAIGWC010000207          232 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.denovo.213, whole genome shotgun sequence.
ACCESSION   DAIGWC010000207 DAIGWC010000000
VERSION     DAIGWC010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.denovo.213"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
BASE COUNT           79 a           35 c           45 g           73 t
ORIGIN      
        1 gagaaaaagc atggaatgcg ctgcatcagg tatcgaggct tagaaaaaaa tcaggtgcat
       61 acgatgcttg tttttgccga aatgagtctg aaaaaattgg tcacttagca gtgggagcat
      121 atgtcttcat attttttatt atacaaaaat agacaaaagt atcagtctac actcttagta
      181 aagaggaaac tgatactttt gtctacagta tgatatttct tacatctact tt
//
LOCUS       DAIGWC010000208        22597 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.guided.044, whole genome shotgun sequence.
ACCESSION   DAIGWC010000208 DAIGWC010000000
VERSION     DAIGWC010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.guided.044"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(134..577)
                     /locus_tag="NOB74_002842"
     CDS             complement(134..577)
                     /locus_tag="NOB74_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HCI1221952.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="NOB74_002843"
     CDS             complement(795..2135)
                     /locus_tag="NOB74_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1221953.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="NOB74_002844"
     CDS             2404..3300
                     /locus_tag="NOB74_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCI1221954.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="NOB74_002845"
     CDS             complement(3450..4391)
                     /locus_tag="NOB74_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI1221955.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="NOB74_002846"
     CDS             4517..5638
                     /locus_tag="NOB74_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI1221956.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="NOB74_002847"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="NOB74_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCI1221957.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="NOB74_002848"
     CDS             7426..7992
                     /locus_tag="NOB74_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI1221958.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="NOB74_002849"
     CDS             8203..9264
                     /locus_tag="NOB74_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI1221959.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="NOB74_002850"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="NOB74_002850"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCI1221960.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="NOB74_002851"
     CDS             10177..12159
                     /locus_tag="NOB74_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1221961.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="NOB74_002852"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="NOB74_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCI1221962.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="NOB74_002853"
     CDS             12881..14305
                     /locus_tag="NOB74_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1221963.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="NOB74_002854"
     CDS             complement(14486..15259)
                     /locus_tag="NOB74_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI1221964.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="NOB74_002855"
     CDS             complement(15256..16161)
                     /locus_tag="NOB74_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1221965.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16315..16635)
                     /locus_tag="NOB74_002856"
     CDS             complement(16315..16635)
                     /locus_tag="NOB74_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HCI1221966.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17109..17795
                     /locus_tag="NOB74_002857"
     CDS             17109..17795
                     /locus_tag="NOB74_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HCI1221967.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17797..18741
                     /locus_tag="NOB74_002858"
     CDS             17797..18741
                     /locus_tag="NOB74_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HCI1221968.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18940..19584
                     /gene="pcp"
                     /locus_tag="NOB74_002859"
     CDS             18940..19584
                     /gene="pcp"
                     /locus_tag="NOB74_002859"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HCI1221969.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19663..20940
                     /locus_tag="NOB74_002860"
     CDS             19663..20940
                     /locus_tag="NOB74_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1221970.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            21198..22415
                     /locus_tag="NOB74_002861"
     CDS             21198..22415
                     /locus_tag="NOB74_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI1221971.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
BASE COUNT         7297 a         4131 c         4666 g         6503 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcgccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa
    16261 ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg
    16321 gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt
    16381 ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc
    16441 aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa
    16501 aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa
    16561 accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa
    16621 ttccatccat gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa
    16681 aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat
    16741 tgtatatctt tttctgtagt atagcacacc tatccagata tcggcaatct catacttttt
    16801 agtaaagtgt accaagcact gacggatata tcgttagcgg aaaagaagat gaatgctttg
    16861 caatttcata gaaagaagtt gttatttatt aatcatttaa aaaaaacagt aactagacct
    16921 tatttctata tattatcggg caataaatta aaaaaagctt taccttacaa taagtaagat
    16981 aatttttgtg ataaaaaaat aacgaaaaat atttaaaaat agtgtctatt tcgtgagaaa
    17041 acaactatat tttttatgtg ttttgcttta taattaaaaa aatattgtca ttttatggag
    17101 gaaaatatat ggaaaattat cttagccttt taggcgtctt gattgttatt ctcgggtttg
    17161 catttaaatt agactcgata ttgatcgtaa tggttgcttt agttgttaca gctttgactg
    17221 gcggtcttgg cattcaagga atgttagaac ttttaggtac aagttttgta aacaatcgcg
    17281 ggatggcgat ttttatcatc attatgttgg caacaggaac gcttgaaaga aatggtctga
    17341 aagaatcagc ggcttccttg atcaagcgat tcaagaaagt atctgctggt atgattgtag
    17401 atatttatgg gatctttcga atgatctttg cggcttttaa cgtgagtttt ggtggagttg
    17461 ctggatttgt tcgtccaatc attttaccga tggcattggg gaccatcgaa tcaaaagggt
    17521 tagaagtcca tcctaagcat gaagaagaac taaaaggtat ggcttcagct atggaaaatg
    17581 tctgctggtt ctttggccaa gtactattca tcggaggagc aggggcgttg ctagtccaat
    17641 caacactgaa agatctagga tatgacgtaa cattgggaca gcttgcttta gtggaagttc
    17701 cagtggctat cacggcttta gttgtggcaa gtgtctactt ctatcttaaa gaaaagaaat
    17761 tagcgaagaa atattatcca ggaaaggggc aataagatgg acttttttac aaatcctgat
    17821 attttattag gcgataaatt actggagatc ctttatatcg tgatgggact cgtattgatt
    17881 tacactggag taagaaattt aacagataaa accaatcctc atcgttatgg gtcagccttt
    17941 ttctggacgg tcttaggggt agttattgca ggaggaagat ggcttccggc aatcgtgaac
    18001 ggtggcttga tctttgcgat gaccatacca gcaattgcta agaaagtcag caaaggagaa
    18061 agccggcttc catcaaaaga atatatggaa aaaatgtcag acaaactagg aatgaaaatt
    18121 tttattccag ctttgagtat cggtgtcttt gcgatcttgt ttgctctatt taccaattta
    18181 ggtgctttag tcggcgtggg cgtcggtgtt tttgcagcca tgctaatctt gatgttcttt
    18241 tctcgagata atcgaccaag tacattttta gatgatgcag cagatatgct gggcacagta
    18301 gggccgttaa gcatgttgcc aatgctttta gcttctctag gtgcggtatt tacaagcgct
    18361 ggagttggga cagtgatttc caatgcagta ggtacgatcg ttccagaagg aaatgtgaac
    18421 atcggcatca tcatttacgc tcttggcatg gtgatattta cggtaatcat ggggaatgca
    18481 tttgcggcca tcaccgtgat gacggttggg atcggtgcac cattcgtatt tagtcatgga
    18541 gcgaatccag cgttaatagg aatggttgca ttgacttgcg gtttttgtgg gaccctgctg
    18601 acaccgatgg ctgctaactt caatatcgtg cctgtagcga tgctggagat gaaagacaaa
    18661 tacggagtga tcaaaaacca gttgtttatt gcgttattta tgctagtttt ccaaattgct
    18721 tatatgattc tatttaaata atagaagaga ggggttgtga cagaataatt gtcgcaacct
    18781 cttctaacat tgtagtggaa cactattttt ttataagaat atattaagtt tgatctgtta
    18841 tgttatttaa actattgttt cctttattta cgctgttcaa ggaaaatggt atgataaaag
    18901 ataaccatat gttaaatcaa tcggacggag gaacaacaga tgaaagtact agtaacaggt
    18961 tttgatccat ttggtgggga caaagtgaat ccagcctatg aagcagtaaa aaaaatgcca
    19021 gatgaaatca gcggtgctga aatcatcaaa gtggaagtac cgaccgtatt cgaaaaaagc
    19081 agtcaagtag tcaaagaagc catccaacag caccaaccag atgtcgtgat ctgtgtcgga
    19141 caagcaggtg ggcggtcagc agtctcgttc gaacgtgtcg caatcaatct agcagaagca
    19201 agaatccctg ataatgaagg aaatcagcca ttcgatacgg ctttagaaga aaacggtcca
    19261 gccgcttact ttacctcatt gccaatcaaa gcaatgacaa aaaatgtaca agatcatggt
    19321 ctaccagcgt acatctctta tacagcagga acatttgtct gcaatgatat catgtatcgt
    19381 ttgcttcatt tgatcgaaac acaattcccg gcaattcgag gtgggttcat ccacgtgcca
    19441 ttctcacccg atcaagtgat cgatcgtcca gtgggtacgc cttctatgtc tttagaagac
    19501 attgcttctt ctttgactta tgcagttgaa gcagcagtag aaaataaaga agatatttcc
    19561 ggaaatgccg gaacaactca ctaatttagc aagaaacact ggctggttgc taacgttatg
    19621 ttagtagcca gctttttgta attagaaagg aaagaaacag ccgtggaaga atggcaatcc
    19681 gtctttgaag aatggtttcc aaaagaaatc agcaaaagct atcccatcaa aatttctaaa
    19741 caatacacaa gcagtcaacg ttgggagatc tatgcaaaat taacgaaaaa acagcgggaa
    19801 ctagtcgata agcaccgccg atatctaatc agctctcgtt ttatggaaga acattattta
    19861 gctgcaacag attgggtgtt ttctgacttc aagatcaatc cgttttttcg aacaaaacga
    19921 agccagcaaa aattgtattg tgagtgtggt agagaattaa aagtgcaata catcgttaaa
    19981 tcgccaaaaa ccggaaagat cctaaaacta ggcatcaacc actttgccga tcacctgcat
    20041 gtctctccga cagtggcagc ttcgatccat cagggaatga caaaagttga tctggcctta
    20101 gacgaattat tatggcttaa gcagaagaat atcgattttc ctgaaggact atggcaaaaa
    20161 tactgttttg tcttgtacca aaatcgtcgg atgaaacagc catatttacc ggatataaaa
    20221 ttagctcagc ggctcgcaga atttcgccaa gtagaaatgc cgatttacat agcggattat
    20281 caagcattgg aaaatgaaat caagaaaata agtgaacaca tcaatgggca gtcaaaaaag
    20341 cgacagataa aaaaagaact atttgacgac tttgcagaag aattagtaaa ggatgtagaa
    20401 gaattcttga tcaactatcg cgcattttta cgtaaagatt ggcaatccat cgtatatgaa
    20461 gaagtgccag tacatcctaa tgcttatttt gaaacattta tttccgtgtt gagaaagaca
    20521 aaacgtcaac gaacaccaga agtcactgct cagatggaat attttgcgaa aaaccaacga
    20581 ttcatccaac caaaaatcta tctatttatt tggaagcaat attgtcgcta tggttttaca
    20641 gaagggttct tcgacagcat tcctcggata gtcagaaatg gttttttaaa agtattgcgt
    20701 aaagaacgag aagctataca atctgctgat aagaaagacc gtacagtctc aaaagaaaaa
    20761 tggcaactag tagtgaaaga tatccaatct ggaaatgtgc aagagacaat cgacaaatgg
    20821 aaaggaaaac attatcgttt tactgaagct cagaaacaag cgttggaata ttatcagaag
    20881 ttagaagaat cactgcgttt caatgatgag gcaagaaagt atctgaagga attactataa
    20941 aaaacatact aagattagag gggaacatca ttgacgaatg atgttctcct ctattttcta
    21001 tttttagatt atagtgaaga gtgaaagaaa gttcgaacaa agccttgagg actacgagtc
    21061 cctatcaaaa accgaacttc tttactgtca ttttagaatc aggtttacgt atgttggggc
    21121 catgagcccg tgtataggaa attggaatcg aaatgaagca gtaaagttct ttcaaaactt
    21181 aaaaaggagg aaaacaaatg ccttacattc ttgcattaga tgtttcaatg ggacacagct
    21241 acagtgtcct atacaaagac gacacctgct tatttgaaga cgagattgaa cacactcaaa
    21301 gaggatttca tgcattactc gaagagatcc agcacttgcc tgagcgtcca ttgattgttt
    21361 ttgaagcaac ggggatttat tccagaccag tcgaaaagtt ctttcaagat catcactttt
    21421 cttactgttt gttaaacccg ttagaggcga aaaaacagat ggaagaaagc accttacgca
    21481 gttggaaaac agataaatcg gatgcccacc ggctcgcaca gactcatctt aaaaatcaac
    21541 gtcagccaaa agaagtacaa agcaattttt acttagagat gcgcgattta gcccgttttt
    21601 atcaagaaat tgagaagaaa atcactcgtc tgcgcatgga tttacacaac tgccttcaat
    21661 tgacttttcc agagcttgaa cagttctttt caaacaggct gaccccttac gcattgacat
    21721 tgatccgtct ttttccccat ccagattttg tattggcatc tactcggaca aaaataaaaa
    21781 ataaactgat caacgaaaca cggaaaaaaa tctccgcgaa tcgtgccgag caaaaggcag
    21841 atcaaatcat ccactatgca cagtgtgcct atccagctgt tgaaaaagac agtatccact
    21901 gtcaaaaaac gatctattac gccgaacttc tccaagattt actcgaacaa aaaaaagcac
    21961 tggcgacaca aatgatcaaa aaagccgaag gctctccttg ctttttgttg taccaaacgt
    22021 tccctgggat tggcgcactc acagccgctt tattgctcgg tgaattagga gatatcacac
    22081 gatttaaaac ccataaacaa ttgaatgcct ttgtcggaat cgacatccga cggtatcatt
    22141 caggtaagta tactggccaa gaccgcatca ataagcgtgg taatcccaaa gcacggaaaa
    22201 ttattttctt caccattcga aatatgattc gccagcaacg cgcagctcct aatcatattg
    22261 tcgattatta ctacaaatta aaaaagcaac ctatccctaa gaaagataag gttgccacag
    22321 ttgcttgtat gaacaagctt ctgaaatgta tgcacgctat ggttagggca catacagagt
    22381 acgactatgc gtacgcggtc tcagtggacc attaactaaa ccacttacag tataccactt
    22441 ctttgcccag atcgaaaatt ttttacgaac ggggctttat ttggtgtgct ttgattttgt
    22501 cgctttcgtt tacgagctat ttttcttgca ccttttactt gactaatcgt aggaaataga
    22561 ggctgggaca gaagcgttta actccaagaa ataagaa
//
LOCUS       DAIGWC010000209        10031 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.guided.087, whole genome shotgun sequence.
ACCESSION   DAIGWC010000209 DAIGWC010000000
VERSION     DAIGWC010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.guided.087"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            84..821
                     /gene="erm(B)"
                     /locus_tag="NOB74_002862"
     CDS             84..821
                     /gene="erm(B)"
                     /locus_tag="NOB74_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCI1221972.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1018..3984)
                     /locus_tag="NOB74_002863"
     CDS             complement(1018..3984)
                     /locus_tag="NOB74_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HCI1221973.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            4130..4705
                     /locus_tag="NOB74_002864"
     CDS             4130..4705
                     /locus_tag="NOB74_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1221974.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            4919..5614
                     /gene="vanR"
                     /locus_tag="NOB74_002865"
     CDS             4919..5614
                     /gene="vanR"
                     /locus_tag="NOB74_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCI1221975.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            5592..6746
                     /locus_tag="NOB74_002866"
     CDS             5592..6746
                     /locus_tag="NOB74_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCI1221976.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            6961..7929
                     /locus_tag="NOB74_002867"
     CDS             6961..7929
                     /locus_tag="NOB74_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCI1221977.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            7922..8953
                     /gene="vanA"
                     /locus_tag="NOB74_002868"
     CDS             7922..8953
                     /gene="vanA"
                     /locus_tag="NOB74_002868"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCI1221978.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAFITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            8959..9567
                     /locus_tag="NOB74_002869"
     CDS             8959..9567
                     /locus_tag="NOB74_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCI1221979.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         3119 a         1878 c         2049 g         2985 t
ORIGIN      
        1 taagaaccgt caggtttagc taagtggtga gtagttcacc ttctgtattt atttatagat
       61 gtaatcactt caggagtgat tacatgaaca aaaatataaa atattctcaa aactttttaa
      121 cgagtgaaaa agtactcaac caaataataa aacaattgaa tttaaaagaa accgataccg
      181 tttacgaaat tggaacaggt aaagggcatt taacgacgaa actggctaaa ataagtaaac
      241 aggtaacgtc tattgaatta gacagtcatc tattcaactt atcgtcagaa aaattaaaac
      301 tgaacattcg tgtcacttta attcaccaag atattctaca gtttcaattc cctaacaaac
      361 agaggtataa aattgttggg aatattcctt accatttaag cacacaaatt attaaaaaag
      421 tggtttttga aagccatgcg tctgacatct atctgattgt tgaagaagga ttctacaagc
      481 gtaccttgga tattcaccga acactagggt tgctcttgca cactcaagtc tcgattcagc
      541 aattgcttaa gctgccagcg gaatgctttc atcctaaacc aaaagtaaac agtgtcttaa
      601 taaaacttac ccgccatacc acagatgttc cagataaata ttggaagcta tatacgtact
      661 ttgtttcaaa atgggtcaat cgagaatatc gtcaactgtt tactaaaaat cagtttcatc
      721 aagcaatgaa acacgccaaa gtaaacaatt taagtaccgt tacttatgag caagtattgt
      781 ctatttttaa tagttatcta ttatttaacg ggaggaaata attctatgag tcgcttttgt
      841 aaattataaa agaattgttt taatgcaggt ataaaagatg aacccgcacc aacaccgcca
      901 ccaattttag atagctttga ttggtacatt tttagcgcta ttcggggtag cgtcaggaaa
      961 atgcggattt acaacgctaa gcctattttc ctgacgaatc cctcgttttt aacaacgtta
     1021 agaaagtttt agtggtctta aagaatttaa tgagactact ttctctgagt taaaatggta
     1081 ttctcctagt aaattaatat gttcccaacc taagggcgac atatggtgta acaaatcttc
     1141 attaaagcta cctgtccgtt ttttatattc aactgctgtt gttaggtgga gagtattcca
     1201 aatacttata gcattgataa ttatgtttaa agcactggct ctttgcaatt gatgctgtat
     1261 ggtgcgttct ctaagctcac cttgttttcc gaagaaaata gctcttgcca atccattcat
     1321 ggcttctcct ttattcaatc ctctttgtat ttttcttctt aatgattcat ccgatatata
     1381 attcaaaata aagatcgttt tttctattcg gcccatctca cgtaaggctg tagctaagct
     1441 gttttgtctt gaataggaac ctagcttccc cataataagg gatgctgaaa ctgttccctc
     1501 ccttatagaa tgagctaatc gcaaaacatc ctcataattt tctttaatga cctttgtatt
     1561 tatttgtcca cgtaaaatgg cttctagttt tggatactca cttgctttat ctatcgtaaa
     1621 taattttgag tccgataaat cccttattct tggggcaaat ttaaatccta ataaatgagt
     1681 cagtccgaat atttggtcag tgtaaccggc agtgtctgta taatgttcct ctatgtttag
     1741 atccgtctca tgatgtaaca aaccatccaa aacatgaatc gcatctcttg aattagtatg
     1801 aataatcttt gtgtagtaag aagagaattg atcacttgta aatcggtaga tggtggctcc
     1861 ttttccagtt ccataatgtg gatttgcatc tgcatgtagt gatgaaacac ctagctgcat
     1921 tctcatacca tctgacgaag atgttgtacc gtcgccccaa tagaaaggca attgtaattt
     1981 atgatgaaag tttactaata tggcttgggc tttattcatg gcatcttcat acatgcgcca
     2041 ttgagataca ttggctagtt gcttatatgt aagtccgggt gtggcttcgg ccatcttgct
     2101 caagccaata ttcattccca ttcctaaaag ggcagccatg ataatgattg tttcttcctt
     2161 atctggtttt cgattattgg aagcatgagt gaattgctca tgaaatcctg ttatatgggc
     2221 cacatccatg agtaaatcag ttaattttat tcttggtagc atctgataaa ggcttgcact
     2281 aaattttttt gcttcttctg gaacatcttt ttctaagcgt gcaagtgata gctttccttt
     2341 ttcaagagaa accccatcta acttattgga attggcagct aaccacttta acctttcatt
     2401 aaagctgctg gttctctccg ttatataatc ttcgaatgat aaactaactg ataatctcgt
     2461 attccccttc gattgattcc atgtatcttc cgaaaacaaa tattcctcaa aatccctata
     2521 ttgtctgctg ccaacaatgg aaacatctcc tgcccgaaca tgctcccgaa gttctgttaa
     2581 aacagccatt tcatagtaat gacgattaat tgttgtacca tcatcctcgt ataaatgtct
     2641 tttccatcgt tttgaaataa aatccacagg tgagtcatca ggcacttttc gctttccaga
     2701 ttcgttcatt cctcggataa tctcaacagc ttgtaaaagt ggctcatttg cctttgtaga
     2761 atgaaattcc aatactctta atagcgttgg cgtatatttt cttagtgaat aaaaccgttt
     2821 ttgcagtaag tctaaataat catagtcggc aggacgtgca agttcctgag cctcttctac
     2881 tgaagagaca aaggtattcc attcaataac cgattctaaa accttaaaaa cgtctaattt
     2941 ttcctctctt gctttaatta atgcttgtcc gatgttcgta aagtgtataa ctttctcatt
     3001 tagcttttta ccgttttgtt tctggatttc ctcttgagcc ttacgacctt ttgataacaa
     3061 actaagtatt tgcctatcat gaatttcaaa cgctttatcc gttagctcct gagtaagttg
     3121 taataaatag atggttaata tcgaataacg tttattttct tgaaagtcac ggaatgcata
     3181 cggctcgtat cttgagccta agcgagacag ctgcaacagg cggttacggt gcaaatgact
     3241 aatttgcact gtttctaaat ccattcctcg tatgtattcg agtcgttcta ttatttttag
     3301 aaaagtttcg ggtgaaggat gacccggtgg ctcttttaac caacccaata tcgttttatt
     3361 ggattcggat ggatgctgcg aggtaataat cccttcaagc ttttcttttt gctcatttgt
     3421 tagagattta ctaaccgtat taaatagctt cttttcagcc attgcccttg cttcccacac
     3481 cattctttca agtgtagtga tagcaggcag tataattttg ttttttctta gaaaatctat
     3541 gcattcatgc agtagatgaa tggcatcacc attttccaaa gctaattgat gaaggtactt
     3601 aaatgtcatt cgatattcac tcagggtaaa agttacaaag tcgtattcac ttcgaatttc
     3661 tttcaaatga tcccaaagtg tattttccct ttgaggataa tgatcaagcg aggatggact
     3721 aacaccaatc tgtttcgata tatattgtat gaccgaatct gggatgcttt tgatatgagt
     3781 gtatggccaa ccgggatacc gaagaacagc taattgaaca gcaaatccta aacggttttc
     3841 ttccctcctt cgcttattaa ctatttctaa atcccgtttg gaaaaagtga agtaggtccc
     3901 cagtatccat tcatcttcag ggatttgcat aaaagcctgt ctctgttccg gtgtaagcaa
     3961 ttctctacct ctcgcaattt tcattcagta tcattccatt tctgtatttt caatttatta
     4021 gttcaattat atatcaatag agtgtactct attgatacaa atgtagtaga ctgataaaat
     4081 catagttaag agcgtctcat aagacttgtc tcaaaaatga ggtgatattt tgcggaaaat
     4141 cggttatatt cgtgtcagtt cgactaacca gaatccttca agacaatttc agcagttgaa
     4201 cgagatcgga atggatatta tatatgaaga gaaagtttca ggagcaacaa aggatcgcga
     4261 gcaacttcaa aaagtgttag acgatttaca ggaagatgac atcatttatg ttacagactt
     4321 aactcgaatc actcgtagta cacaagatct atttgaatta atcgataaca tacgagataa
     4381 aaaggcaagt ttaaaatcac taaaagatac atggcttgat ttatcagaag ataatccata
     4441 cagccaattc ttaattactg taatggctgg tgttaaccaa ttagagcgag atcttattcg
     4501 gatgagacaa cgtgaaggga ttgaattggc taagaaagaa ggaaagttta aaggtcgatt
     4561 aaagaagtat cataaaaatc acgcaggaat gaattatgcg gtaaagctat ataaagaagg
     4621 aaatatgact gtaaatcaaa tttgtgaaat tactaatgta tctagggctt cattatacag
     4681 gaaattatca gaagtgaata attagccatt ctgtattccg ctaatgggca atatttttaa
     4741 agaagaaaag gaaactataa aatattaaca gcctcctagc gatgccgaaa agccctttga
     4801 taaaaaaaga atcatcatct taagaaattc ttagtcattt attatgtaaa tgcttataaa
     4861 ttcggcccta taatctgata aattattaag ggcaaactta tgtgaaaggg tgataactat
     4921 gagcgataaa atacttattg tggatgatga acatgaaatt gccgatttgg ttgaattata
     4981 cttaaaaaac gagaattata cggttttcaa atactatacc gccaaagaag cattggaatg
     5041 tatagacaag tctgagattg accttgccat attggacatc atgcttcccg gcacaagcgg
     5101 ccttactatc tgtcaaaaaa taagggacaa gcacacctat ccgattatca tgctgaccgg
     5161 gaaagataca gaggtagata aaattacagg gttaacaatc ggcgcggatg attatataac
     5221 gaagcccttt cgcccactgg agttaattgc tcgggtaaag gcccagttgc gccgatacaa
     5281 aaaattcagt ggagtaaagg agcagaacga aaatgttatc gtccactccg gccttgtcat
     5341 taatgttaac acccatgagt gttatctgaa cgagaagcag ttatccctta ctcccaccga
     5401 gttttcaata ctgcgaatcc tctgtgaaaa caaggggaat gtggttagct ccgagctgct
     5461 atttcatgag atatggggcg acgaatattt cagcaagagc aacaacacca tcaccgtgca
     5521 tatccggcat ttgcgcgaaa aaatgaacga caccattgat aatccgaaat atataaaaac
     5581 ggtatggggg gttggttata aaattgaaaa ataaaaaaaa cgactattcc aaactagaac
     5641 gaaaacttta catgtatatc gttgcaattg ttgtggtagc aattgtattc gtgttgtata
     5701 ttcgttcaat gatccgaggg aaacttgggg attggatctt aagtattttg gaaaacaaat
     5761 atgacttaaa tcacctggac gcgatgaaat tatatcaata ttccatacgg aacaatatag
     5821 atatctttat ttatgtggcg attgtcatta gtattcttat tctatgtcgc gtcatgcttt
     5881 caaaattcgc aaaatacttt gacgagataa ataccggcat tgatgtactt attcagaacg
     5941 aagataaaca aattgagctt tctgcggaaa tggatgttat ggaacaaaag ctcaacacat
     6001 taaaacggac tctggaaaag cgagagcagg atgcaaagct ggccgaacaa agaaaaaatg
     6061 acgttgttat gtacttggcg cacgatatta aaacgcccct tacatccatt atcggttatt
     6121 tgagcctgct tgacgaggct ccagacatgc cggtagatca aaaggcaaag tatgtgcata
     6181 tcacgttgga caaagcgtat cgactcgaac agctaatcga cgagtttttt gagattacac
     6241 ggtataacct acaaacgata acgctaacaa aaacgcacat agacctatac tatatgctgg
     6301 tgcagatgac cgatgaattt tatcctcagc tttccgcaca tggaaaacag gcggttattc
     6361 acgcccccga ggatctgacc gtgtccggcg accctgataa actcgcgaga gtctttaaca
     6421 acattttgaa aaacgccgct gcatacagtg aggataacag catcattgac attaccgcgg
     6481 gcctctccgg ggatgtggtg tcaatcgaat tcaagaacac tggaagcatc ccaaaagata
     6541 agctagctgc catatttgaa aagttctata ggctggacaa tgctcgttct tccgatacgg
     6601 gtggcgcggg acttggattg gcgattgcaa aagaaattat tgttcagcat ggagggcaga
     6661 tttacgcgga aagcaatgat aactatacga cgtttagggt agagcttcca gcgatgccag
     6721 acttggttga taaaaggagg tcctaagaga tgtatataat tttttaggaa aatctcaagg
     6781 ttatctttac tttttcttag gaaattaaca atttaatatt aagaaacggc tcgttcttac
     6841 acggtagact taataccgta agaacgagcc gttttcgttc ttcagagaaa gatttgacaa
     6901 gattaccatt ggcatccccg ttttatttgg tgcctttcac agaaagggtt ggtcttaatt
     6961 atgaataaca tcggcattac tgtttatgga tgtgagcagg atgaggcaga tgcattccat
     7021 gctctttcgc ctcgctttgg cgttatggca acgataatta acgccaacgt gtcggaatcc
     7081 aacgccaaat ccgcgccttt caatcaatgt atcagtgtgg gacataaatc agagatttcc
     7141 gcctctattc ttcttgcgct gaagagagcc ggtgtgaaat atatttctac ccgaagcatc
     7201 ggctgcaatc atatagatac aactgctgct aagagaatgg gcatcactgt cgacaatgtg
     7261 gcgtactcgc cggatagcgt tgccgattat actatgatgc taattcttat ggcagtacgc
     7321 aacgtaaaat cgattgtgcg ctctgtggaa aaacatgatt tcaggttgga cagcgaccgt
     7381 ggcaaggtac tcagcgacat gacagttggt gtggtgggaa cgggccagat aggcaaagcg
     7441 gttattgagc ggctgcgagg atttggatgt aaagtgttgg cttatagtcg cagccgaagt
     7501 atagaggtaa actatgtacc gtttgatgag ttgctgcaaa atagcgatat cgttacgctt
     7561 catgtgccgc tcaatacgga tacgcactat attatcagcc acgaacaaat acagagaatg
     7621 aagcaaggag catttcttat caatactggg cgcggtccac ttgtagatac ctatgagttg
     7681 gttaaagcat tagaaaacgg gaaactgggc ggtgccgcat tggatgtatt ggaaggagag
     7741 gaagagtttt tctactctga ttgcacccaa aaaccaattg ataatcaatt tttacttaaa
     7801 cttcaaagaa tgcctaacgt gataatcaca ccgcatacgg cctattatac cgagcaagcg
     7861 ttgcgtgata ccgttgaaaa aaccattaaa aactgtttgg attttgaaag gagacaggag
     7921 catgaataga ataaaagttg caatactgtt tgggggttgc tcagaggagc atgacgtatc
     7981 ggtaaaatct gcaatagaga tagccgctaa cattaataaa gaaaaatacg agccgttata
     8041 cattggaatt acgaaatctg gtgtatggaa aatgtgcgaa aaaccttgcg cggaatggga
     8101 aaacgacaat tgctattcag ctgtactctc gccggataaa aaaatgcacg gattacttgt
     8161 taaaaagaac catgaatatg aaatcaacca tgttgatgta gcattttcag ctttgcatgg
     8221 caagtcaggt gaagatggat ccatacaagg tctgtttgaa ttgtccggta tcccttttgt
     8281 aggctgcgat attcaaagct cagcaatttg tatggacaaa tcgttgacat acatcgttgc
     8341 gaaaaatgct gggatagcta ctcccgcctt ttgggttatt aataaagatg ataggccggt
     8401 ggcagctacg tttacctatc ctgtttttgt taagccggcg cgttcaggct catccttcgg
     8461 tgtgaaaaaa gtcaatagcg cggacgaatt ggactacgca attgaatcgg caagacaata
     8521 tgacagcaaa atcttaattg agcaggctgt ttcgggctgt gaggtcggtt gtgcggtatt
     8581 gggaaacagt gccgcgttag ttgttggcga ggtggaccaa atcaggctgc agtacggaat
     8641 ctttcgtatt catcaggaag tcgagccgga aaaaggctct gaaaacgcat ttataaccgt
     8701 tcccgcagac ctttcagcag aggagcgagg acggatacag gaaacggcaa aaaaaatata
     8761 taaagcgctc ggctgtagag gtctagcccg tgtggatatg tttttacaag ataacggccg
     8821 cattgtactg aacgaagtca atactctgcc cggtttcacg tcatacagtc gttatccccg
     8881 tatgatggcc gctgcaggta ttgcacttcc cgaactgatt gaccgcttga tcgtattagc
     8941 gttaaagggg tgataagcat ggaaatagga tttacttttt tagatgaaat agtacacggt
     9001 gttcgttggg acgctaaata tgccacttgg gataatttca ccggaaaacc ggttgacggt
     9061 tatgaagtaa atcgcattgt agggacatac gagttggctg aatcgctttt gaaggcaaaa
     9121 gaactggctg ctacccaagg gtacggattg cttctatggg acggttaccg tcctaagcgt
     9181 gctgtaaact gttttatgca atgggctgca cagccggaaa ataacctgac aaaggaaagt
     9241 tattatccca atattgaccg aactgagatg atttcaaaag gatacgtggc ttcaaaatca
     9301 agccatagcc gcggcagtgc cattgatctt acgctttatc gattagacac gggtgagctt
     9361 gtaccaatgg ggagccgatt tgattttatg gatgaacgct ctcatcatgc ggcaaatgga
     9421 atatcatgca atgaagcgca aaatcgcaga cgtttgcgct ccatcatgga aaacagtggg
     9481 tttgaagcat atagcctcga atggtggcac tatgtattaa gagacgaacc ataccccaat
     9541 agctattttg atttccccgt taaataaact tttaaccgtt gcacggacaa actatataag
     9601 ctaactcttt cggcaggaaa cccgacgtat gtaactggtt cttagggaat ttatatatag
     9661 tagatagtat tgaagatgta aggcagagcg atattgcggt cattatctgc gtgcgctgcg
     9721 gcaagatagc ctgataataa gactgatcgc atagaggggt ggtatttcac accgcccatt
     9781 gtcaacaggc agttcagcct cgttaaattc agcatgggta tcacttatga aaattcatct
     9841 acattggtga taatagtaaa tccagtaggg cgaaataatt gactgtaatt tacggggcaa
     9901 aacggcacaa tctcaaacga gattgtgccg tttaagggga agattctaga aatatttcat
     9961 acttccaact atatagttaa ggaggagact gaaagagagt ataaaatatt ttgtgtaaat
    10021 gaaaaaatcc a
//
LOCUS       DAIGWC010000210         9732 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.guided.091, whole genome shotgun sequence.
ACCESSION   DAIGWC010000210 DAIGWC010000000
VERSION     DAIGWC010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.guided.091"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(<1..764)
                     /locus_tag="NOB74_002870"
     CDS             complement(<1..764)
                     /locus_tag="NOB74_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1221980.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIP"
     gene            892..1461
                     /locus_tag="NOB74_002871"
     CDS             892..1461
                     /locus_tag="NOB74_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCI1221981.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            1528..2265
                     /locus_tag="NOB74_002872"
     CDS             1528..2265
                     /locus_tag="NOB74_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1221982.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            2496..3764
                     /locus_tag="NOB74_002873"
     CDS             2496..3764
                     /locus_tag="NOB74_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI1221983.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            4251..4715
                     /locus_tag="NOB74_002874"
     CDS             4251..4715
                     /locus_tag="NOB74_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1221984.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            4699..5328
                     /locus_tag="NOB74_002875"
     CDS             4699..5328
                     /locus_tag="NOB74_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI1221985.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            5682..7160
                     /gene="msr(C)"
                     /locus_tag="NOB74_002876"
     CDS             5682..7160
                     /gene="msr(C)"
                     /locus_tag="NOB74_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCI1221986.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            7207..7653
                     /locus_tag="NOB74_002877"
     CDS             7207..7653
                     /locus_tag="NOB74_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCI1221987.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(7852..8367)
                     /locus_tag="NOB74_002878"
     CDS             complement(7852..8367)
                     /locus_tag="NOB74_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI1221988.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            8484..9686
                     /locus_tag="NOB74_002879"
     CDS             8484..9686
                     /locus_tag="NOB74_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1221989.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         3092 a         1717 c         2028 g         2895 t
ORIGIN      
        1 gggatgaata ttttttccgt cccataagta ttgatgatcc catctagagc taatgcacca
       61 aaagtcccgt tatcgaccat caaagaagca ttgtacaata agttatatgt tccgacgatc
      121 gataactgat ctatgctgaa acctagccat tcagctagtt gactgtccac tgacgtttgc
      181 cgggaaatga tcaaaggaac agttttcagt tcctgcggat ggatgacggt ttgctttgct
      241 aaaggatgat ttcgatgtat caaaagtccc caacgatctt gggctggcag tcgaaatgac
      301 tggtattttt gtttgtttgt cggttcgatt acgagtccaa aatcaagtaa tccgctatcc
      361 agtttgtcta tgatatcatc tgcattcccg ctatataaat gaaactggat atcaggatgc
      421 gccttgatca acgaatgaag gctatcagaa atgaaagaga ttgctttagt ttcgcctccg
      481 ccaatgtaga tttctccaga gatgattgcg tcatttgtta aattgttcgc cgttttttct
      541 accaacgaca agatttcttt tccttttgaa taaagatatc gaccagaatc cgtcaactgt
      601 atctctcggg agccccgagt gaaaagtgtc acaccaagtt cttcttctaa atctttcagt
      661 tgttttgaga gagtaggttg cgtgatatgc agagattttg ctgctcggct gatatttttt
      721 tctctagcta ctgctaaaaa atacgtcagt atacgaatat ccattttttc cctcctgttt
      781 ttaaaaaagc ataccactaa gtatagttaa aaggaatagt taagtatgtt ttataagtat
      841 tagacatgat aagccgtccg ttataaagta aggataaaag gagggagcaa aatgacaagc
      901 ctcatcgaaa aacaaatcgt caataaagag attcgagtaa cggatccgct ctttgaagtg
      961 atccatcaga tccaagctga aaacgaagag cctttagcag cgctgaatac tgggtaccat
     1021 gaaccagcag atatccgcaa acggctagaa aatatcatta gtgacaaagt agatgatacg
     1081 gtgactgttc tgctgccttt ttatacagat ttcggcaaac atattagtat agggaaaaat
     1141 gtctttatca atcgtcaagt gatgttcgtt gacttaggtg gcatctgttt agaagattca
     1201 gtattgattg gtcctcgtgt caacctcatc acggtgaacc atctaaccga tccaaaagaa
     1261 cgaagaggct tgttagtaaa gccaatccac atcaagaaaa atgcttggat cggagcagga
     1321 gcaactattc tgccaggcgt aacgattggc gagaatgcca ttgttgcagc gaatgcaact
     1381 gttacgaaag atgtcccaga caataccatc gttgcaggaa tccctgccaa aatcgtcaaa
     1441 cctgtcgaac ggattatttg aacagtaaga tgaaataaga gatagtgagt ataagcaaga
     1501 gatttttcaa aacaggagga gaatagaatg aatgatttat cagaaaaagt gattgtcatc
     1561 atgggcgctt caagcggaat cggtgaagca acaacgaagc tattagcaga aaaaggggct
     1621 aaactagtta tagctgcacg ccgagaagat cgcctaaaag caataaaaga atctttacca
     1681 gaagctgagc tatatattca aacagcagat gtaagagatt ttgcacaagt ccaagcagtt
     1741 atcgatttag cgatggaaaa gttcggtcga atcgatgtat tgtacaataa tgcaggaatc
     1801 atgccaaccg ctccattagt tgaaggtcac cgtgatgaat ggcaaaatat gcttgatatc
     1861 aacatcatgg gtgtgttaaa tggaatttcc gccgtacttc caatcatgga aaaacaaaaa
     1921 tctgggcata tcatttcaac tgattctgtg gcgggacatg ttgtttatcc tgattccgcc
     1981 gtttattgcg gaacaaaatt tgctgtccgt gcaatcatgg aaggattacg tcaagagcaa
     2041 cggcaaaata acatcaaatc tacgatcatc tctccaggag ctgttcaaac tgaattatat
     2101 caaaccatca gcgacaaaaa ggctgctctt gaacttcatg aagcgcaaaa agaatgggga
     2161 ttgacctccg aagatatagc ttctgctgta gcatttgcga tagaaacgcc agaccggatg
     2221 tctgtcagta acatgattat ccgtccgacg acacaggaag tataatccat aacggataat
     2281 atccaaagag aattacttgt taaatagtta ttcaaacgac catcaattta aggcgtgaat
     2341 ggagaagaat attcttcatt tacgtctttt tatgtagaaa aagcaaattt atcaaaaaga
     2401 aacaaatgtt atttaaatat ggacattgac ttgcttttac ttttttagtt acactgttat
     2461 ttaggaaaag tttcataatt caaaggagaa aaaagatgaa agcaaagaat ttattattta
     2521 gcgttattct tttaggaaat ctagcagttg ccaacacaac agtgctagct gaagaatcga
     2581 cagaaactgt cgcaactcag acatcgagtt cttcagaaac aggaattgaa aacgatacag
     2641 agagtacttt gcagtcagct actgtctcag aaaatacaat ttcaaccgaa gaaccaacaa
     2701 ctgaaacaac agaacaaaca caaaccgaag acagtacatc agcagaagct cagaacaatc
     2761 cagagaatgc agaagaaatc acgaaccaat tgacagatgg gcaaacattg acacataccc
     2821 atcaagcaga tttgtctgaa ttcgaaaact atactggcta tgctttttat gctcgctcat
     2881 ctgctaattc tcaacaagcg ttcattgata gtattgcctc aactgcacaa agtttggcaa
     2941 gtgccaatga cttatatgca tcagtcatga ttgctcaagc catcgttgaa agtggctggg
     3001 ggaacagtac tttggcttct gcccctaatt acaatctatt tgggattaaa ggaagctata
     3061 atggccaatc tgttacgatg cctacttcgg aatatgtgaa tgggcaatgg attacggtga
     3121 atgccgcttt tagaaaatat ccttcgtaca aagaatcatt gcaagataac gtaacggtat
     3181 tgaagacgac ttcttttcag ccaggcgttt actactattc cggtgcatgg aaaagcaata
     3241 cgaactctta caaagatgct acggcttggc taacaggtcg ttatgccact gcgcctaatt
     3301 atggttctac attgaacaat gtaatcgaaa cctataatct gacacagtat gatacagcac
     3361 caacttcaac ttctccgatg tatcgtctgt ataaccgtca tacaggagaa catttatata
     3421 cattgaatgc cggagaaaaa aattatctgc caactgtagg ctgggaatat gaagggattg
     3481 cttggcaagc accaaacagc ggacaacctg tctaccgttt atacaatcct tacagtggag
     3541 accatcatta cacaatggca caatctgaga tcaactcttt aacaaaaatc ggttggcgtt
     3601 atgaaggtct aagtttttat tctggtggtt ccaagccaat ttatcgacta tttaatccaa
     3661 atgaaaaaac tggtacccat cactatacct tgagtgctaa ggaaagagat tggctaacac
     3721 cgatgggctg gagatatgaa ggaataggat tttatggtta ttaaaaagag gtagtgaaaa
     3781 agctgccctg catcaagtag taagaacagc caaacaaaaa cagattttca tgttttttgt
     3841 ttggttgaac ttattaccgc agatgcaagt ttttgaacac cgtttactca aaaaaggttg
     3901 tgacaacatc ttgtcataac ttttttatta ctgtttaagc atactgatcc aatttctaat
     3961 attcgacggg attcttgcaa aaggcgattt cggaaatttt tggcggtgta aaattttcta
     4021 ctgcagaaga gctatcttct atagtttgat aagaatcaat aatcttggtt ttagcgttgt
     4081 gctttcttta tcattttttc cgttcattct acaaaaaatt tcttttctct atacttttct
     4141 attgagagcg ttttttttat tacacagctg attctttgac ttttttcttt ttttattcta
     4201 ttattgacaa gtcaatcgtt gacgagtcaa ttattagaaa ggaggaaatt atgtctttag
     4261 aagagattag tcacctttta tatcaaatca aattagccga tcaaaaaatc gtccagatct
     4321 ttgaagaaaa tatcggtata agtcttacta gatacgagat catgatgaga ctgaaagaag
     4381 aaaatccatt gctacaaagc agtttgcaag aaaagttgca gattgatcaa ggagcagtta
     4441 ctcgtcatct gaaggtattg gaagcaaatg gctatgtttc gcgtcagaga aatcctcaga
     4501 acaaccggga agtgtatgta gcgctaacag aaaaagccca gaagaaaatc gagcattgtg
     4561 aaatggacca taaagataca ggttccgtgc tatccccggc tttcagcgat gtagaaatga
     4621 aacaatttct aacactttta gataaattga atacccaact ttgcaatata acaacagaaa
     4681 cgaaagaggt taataataat ggaacaaaaa aatgattttt caacaattat gactggtaga
     4741 agatccgttc gcgtatatga tgaaacatac aaaatcccac acgaagaaat gctggaaatg
     4801 atcaaagaag cgacgactgc accttcttct gtcaatatgc aaccatggcg ctttgtggtc
     4861 gctgaaagcg aggaagcaaa agaaatcttg cgtcctttga tccgtttcaa tacgagacaa
     4921 aatgatactt cttctgcaat ggtcatgatt tttggcgata tgcaatgtta cgaatatggc
     4981 gaagaaatct ataaccaagc ttacgaatca gggaagatgc caaaagaagt cagagatcaa
     5041 caattagctg cgatcattcc ttattacaag agtttttcaa gagaagaaat gaacgatgta
     5101 gtcaaagtcg attctagctt agcggctatg caattcatgt tagttgcgcg tgatcatggc
     5161 tatgaaacaa atccaattgg tggagtcgaa gcagatcagt tggcagaggc atttggtttg
     5221 gataaagacc gttatgttcc agttattatt ttatcaatag gaaaagcggt agaagaaggt
     5281 tacgagtctg ttcgtttagc accagaaaag atcactacgt tcgaataaaa ggttttcagt
     5341 tactattcag tagctattgc tttttttgaa tcgtgtgtgg taacctaata aaaaaggagg
     5401 tcggaaaaat gactgcatcg atgaaattac gtttcgaact tttgaataac aactaaataa
     5461 attcaaaaga catgtataaa caacaatttc atggatggag tatgtccatt ttttcgaacg
     5521 acagtagaat aggtgaaagc tatgacagat ttggtgattt agtcatagtt atttcgttca
     5581 gagtaggaaa agatgtgatg cagttttttt gcaaacagat ttttctgctc ttttttagta
     5641 tcgataattg ttgttttaca tgaaatagga gtgtaaaaca tatggaaaat ttagcagtaa
     5701 atataacaaa tctacaagtc agctttggca accagctaga actatctatt gattctcttc
     5761 gtgtctatca gcaagatcgt atagggatca taggagaaaa tggtgtcggt aaatcgactt
     5821 tgctcaaact aatagccggt gaactttttc ccgatcatgg gaaaatccaa acagagatca
     5881 ccttcaacta cctgcctcaa ttaacctatc tcgctgaagc aaaggaccta aatttggaat
     5941 tagccagtca tttccagtta agactggaag aaacttcaga gcggaaatgg agcggagggg
     6001 aagaacgaaa gatcgagttg atacgtcttc tttcttctta tgaacaaggg atgcttctag
     6061 acgagccaac aacccatcta gatagaaaaa gtattgatcg actgattgaa gagcttcgtt
     6121 attattatgg tacgctggtt tttgttagtc atgatcgcta ttttctagat gagctagcat
     6181 cgaaaatctg ggaagtaaaa gacggagaaa tccgagagtt ttcggggaat tatagtgcct
     6241 atctcactca aaaggaattg gagaaaaaga ctcagctacg agaagcagag tcgatcatga
     6301 aagagaaaaa acgattggaa aaatcgatcc aagaaaagaa aaaacaagcg gaaaagttgg
     6361 aaaaagtgtc cagtaaaaag aaaaagcaac aaatcagacc ggatcggttg tcttcctcta
     6421 aacaaaaaga cagtgtacaa aaagccatcc aaaagaatgc gaaaacatta gagagaagac
     6481 tccaaaaaat aggagaaaca accaagccgc agcagatgaa acaaatccgt tttccagtac
     6541 caaaatctct tgaactccac agccgctatc ccatcatggg acaaaatgtc caattggaaa
     6601 gaagtgggag aacattactg gtaaatggtg attttcagtt ttctttaggt aaaaaaatcg
     6661 cgattgtcgg tgaaaatggt tcaggtaaga caaccttatt agaacatatc cgcaaacaag
     6721 gagaaggaat ccttctctct ccgaaagtaa gctttcaagt atatcagcaa aagggttatc
     6781 aaatgacatc tgaagaatcc atcattcgtt ttgtcatgag acaaacagag ttttcagaat
     6841 cgcttgtccg tagtttgctg aatcacttag ggtttgctca ggaaactttg acgaaaccgt
     6901 tatgtacatt aagtggggga gaagcgaccc gtctgacgat tgctttgctt tttactaagc
     6961 caagtaatgt gttgctgtta gatgaaccga ctaattttat tgatatggca acgatcgaag
     7021 ctttagagaa gctaatgcaa atatatccgg gaacgatttt gtttacttct catgattctt
     7081 actttgtcga gcgtacggct gatgaagttt atgaaataaa agggcagaaa ataaaaaaag
     7141 tacttacgag aaatttttaa atgtgctacg atgattttcg tgacaaattt aaaggagtgg
     7201 tacagattgc ctacaaataa aaaagaagga ataattttta caacaatgat gtgttttttg
     7261 atggtcttgg ggatgagcgc gtataattta tggctgcatc aagatcttca tttatcaagt
     7321 ttgttgattg gtctagtgcc tggattcgtg gtggctttca ttttggatgt cttcatcatc
     7381 ggtgtgctgg cgaaaaaaat tgcctttaaa ctaccagtaa atccagaaag caaggtccaa
     7441 atgatcttaa ctatttcatg cttgatggtt ttaggaatgg tgacatgtat gtctttattc
     7501 ggtgtgatca tggaacaagg aatacctgat caattattct ctgcttatat gaatgcttgg
     7561 aaaatgaatg tgattgccgc tttaccgttg cagttgatca tcgttggccc gctttcaaga
     7621 agtgtgctaa aagcaattca aagtaatgaa tgatggaaca ctgttatttg aaaaaaggcc
     7681 ttggcatgct ttttgtcata gtctcttgaa tgcagttcta gaaaaatagt gatccgaacg
     7741 ataggttttg gcctgtcgtt cggatcgctt tttcttttcc aactgtattg ctcttttatt
     7801 gaagataatt tgctcttcaa tagatatttc tagaaaggtt ctgtttatcc cttactcaaa
     7861 aaactgctgc atttgttctc ttacttgctg acaccattgg agttcctgct gacaaagcat
     7921 aattctgcgc tggatcacaa cataacgtcc aaattcttgt ttcttgtcta gcgagaggtc
     7981 attcaatttt ttttgatttt tttgcatgat tttgttcagc tgttgttctc tagtgaatag
     8041 cagtccagta gctgttgttt tatcgagcgt cgaaaaagca tagatttttg ctagaaattc
     8101 atctttttgc gtaggagcgg gagtttcctc tttgatccat tcctctacaa gagcacgtcc
     8161 ttcatcagtc aagtggtaga tctttttttg agagtgctcg tctttgtcca aaacggtcac
     8221 ataaccctgc tggtctaact tggcaagcgt tgtatagatc tgactgtgat gggcttccca
     8281 aaaaattgtg atcagctgct tcaattcata cccagaacgt ggtttggata aaagcacgca
     8341 taataatata taggctaaag tattcataaa aatcctacct ctcgtcttat tttctttatt
     8401 atatcacagt aaagtttcca cgttttacat gtgcatattt acatgtaaaa taaatcatgt
     8461 atgatgctaa tagagagaaa gggatggaaa tattggagaa tcaaatagat atacaagaac
     8521 aaacaaatga agaaacaaag gggaaaagtt cagcgctagt tgtagcagct acctgtatga
     8581 tcgcttttat gggagtgggt ctagtagacc caatcttaaa aacgattgct gcacagttaa
     8641 acgctacgcc agctgaaacg accctgttat ttactagtta catgttagtc actggtgtgg
     8701 tgatgctatt tacaggtttc ttatctagtc ggatcggttt gaaaaaaaca ttgatgacag
     8761 gattgtttat catcgttgta ttcgctggtc ttggcggatt atctgggaat atcggaatgc
     8821 tgattgggtt acgtgccggc tggggtgtcg ggaatgcttt atttgtctct actgctttag
     8881 caacgatcgt cagtatttta gttggtaaca cagaaaaagc aatcatgatg tatgaagcag
     8941 cacttggctg cggaatggct gttggccctc tagtcggtgg ggtcttgggc agtggttcat
     9001 ggcgttatcc attttttggg gtagcatttt tgatgttttg cggttttata gccctagcgg
     9061 tacttttacc tgaaactgag aaaccaaaga gaaaagtagg cctttgggaa ggtgtcaaag
     9121 cgttaagcaa tcataaactt cgttcagttg gactaatcgc attgttatat aatttcggat
     9181 tctttacttt acttgcgtat gcgccatttt tattgattgg ctattctgaa ttagaagtcg
     9241 gttttgtatt ttttggctgg ggtgtgcttc tggctattgc ttcgattttc gttgcaccgg
     9301 ctcttgagcg gaagtttacg acttatcgga caattttagc agcatttgtc ttattcatta
     9361 tttgtttgct gttattagga gctggaactt ctatgccagt ccttgtaccg atcagcattg
     9421 tgttagcagg atttttccaa ggaattatca atacactgtt gacgacgatt gctatggaaa
     9481 taccaggtct gcaacgaaac gttgcttcgt ccagctatag ttttgtccgc tttttcggtg
     9541 gagctttagc accatttatt gcaggtgtga ttggtgaaca tattggtgaa agctatgcgt
     9601 tttattttgc aggtgccatt gttcttatca gtgtatgttg tatcatttat caccgtaatt
     9661 attttgctac aaatgaagaa gaataagaaa tcagaggttg tgaaaaagct gtcctgcatc
     9721 aagtcataag aa
//
LOCUS       DAIGWC010000211         3468 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.guided.134, whole genome shotgun sequence.
ACCESSION   DAIGWC010000211 DAIGWC010000000
VERSION     DAIGWC010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.guided.134"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            322..1014
                     /locus_tag="NOB74_002880"
     CDS             322..1014
                     /locus_tag="NOB74_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI1221990.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1341..1838
                     /gene="dfrG"
                     /locus_tag="NOB74_002881"
     CDS             1341..1838
                     /gene="dfrG"
                     /locus_tag="NOB74_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCI1221991.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1910..>3468)
                     /locus_tag="NOB74_002882"
     CDS             complement(1910..>3468)
                     /locus_tag="NOB74_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCI1221992.1"
                     /translation="VVEEIKRLIEINSIQDVEPDYQFHKEGCSEEESTPFNEPKQFYK
                     RGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPMFAKMVVGRVSVSRTCD
                     ILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWLNTDKMHYYLNNVRKKG
                     QGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISMDELNEDTRKFKEDHLN
                     TFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRFVDGLNVDAPYTTTAHY
                     WLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHFICQVNKTKSRKQCLKE
                     FGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEEAISKDGERYRKYADNP
                     IKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTNSFIQQIRRYISSLERP
                     LTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSADKKVLTPAQRLGITDKQ
                     FDWKDIIYFK"
BASE COUNT         1221 a          541 c          603 g         1103 t
ORIGIN      
        1 tttcataggt aaaagaagca tgacaattta tgacaaatcc gcgttttttg taataaatac
       61 agtaatctat gaaatgaaaa gggttacgtt taataaaact tgcttttttg tttttgttca
      121 ccataaatat ttatttaaga aagtattaac ctgcattttt ctctataaaa aagatttttt
      181 aaatagataa aaaaggagga ttaaatgagt atttgatagt atttatatta aaattacata
      241 tgtaatttaa aaacgcttga cattgtgttt gagatcactt acttttagca tgtaaaagta
      301 ttggattaag gagctatgca aatgaaaaag aaatttatta ctggtgggat tgtcgttgca
      361 tttctatgtc taattggcta cacaggcacg cggtacgcaa atgaaattat tttgtggggt
      421 ggagagacag atattgatac aatcaatgag aatctgacac agcttgatca tacattgaca
      481 gataaagagc aagcgattac agatcttacc gctcgactag cacaaaaaga acagacattg
      541 caagattcaa aggcagatgt ccaagaatac caaacaaaag taaatgaatt agaaaaccaa
      601 aaaaatcaat cggcagcaga aaaacaaaac ttagaaagtc aattagtcag caaggatgca
      661 caactacaaa gcaaacaaaa tgaaatcaat gtcaaactag atgagatcaa ccaaaaaaat
      721 gatgaaatca atcatctgaa tgcagattgg acagcaagac tacaagaagc acaagcaaaa
      781 ctttcagaat tacaaaatac tgtaaatggt ttgaatcaac aaatcgcaac actgacacaa
      841 gaaaaaacaa atgtagaaac tcagttaaca gatacacaaa agaaattaga cgaagcaact
      901 gctgaaaact caagcttgaa acaatatatt caaaagttag aaaaagcaaa agatgaagtg
      961 gaagatacag ctgataaatc tcagcaaatt gttgaagaac atttgcgtaa ataatctttc
     1021 ttaacaagta aacctaaatt agtaaagaag caacagtaat ctatactaag tagttcagtt
     1081 ttggagtaca aaatgacaaa atgtacttca aaatggacta cttttttcat tttaacttac
     1141 ataccaaatt acatacaaaa tgatttataa aatgcaattg aaaatgataa ttgaatgaaa
     1201 atttgtgatt ttgtggtatt atgataatat aacttataga aaaaattgct tattcaacta
     1261 acgggcagga taatgagaaa aggttttttg atagaaataa gaaattagat ggtaaattag
     1321 ttaaaaaggc tgtgttataa atgaaagttt ctttgattgc tgcgatggat aagaatagag
     1381 tgattggcaa agagaatgac attccttgga ggattcccaa ggactgggaa tatgttaaaa
     1441 atactacaaa gggacatccg ataatattag gtaggaagaa ccttgaatca atcggaagag
     1501 ccttacctga cagaagaaat attattctga cgagagataa ggggtttacc tttaatggtt
     1561 gtgaaattgt tcattcaata gaagatgttt ttgagttatg taaaaacgaa gaagaaattt
     1621 ttattttcgg aggagaacag atttataatt tgtttttccc ttatgttgag aaaatgtaca
     1681 tcacaaaaat acatcatgaa ttcgaaggag atactttttt tccagaagtg aattatgagg
     1741 aatggaatga ggtatttgcc caaaaaggga taaagaatga taaaaatccg tataactact
     1801 attttcatgt atatgaaaga aaaaacttat tgagttaacg ggtgcgttaa ttgaagaaga
     1861 acagtaaaga taaagcacaa gagcttggga ttactccaag ctctttttgt catttgaaat
     1921 aaattatatc tttccaatca aattgtttat ctgtaatccc taatctttga gcaggtgtca
     1981 aaaccttttt atccgctgat ttaaaagggc gacaaaagtt gtagtaagtt cttagaattg
     2041 taatcgcaaa ttgagcatac ttcggattga agttagcgta aatatagctc ttcttatcac
     2101 cacgagctgt tgttaatggt ctttcaagag atgatatata acgtcttatc tgttgaataa
     2161 agctattggt cgaatggtca ttaacattta atagcatctt tgcgatttcg tttggttcca
     2221 gagcagataa atccgttcta caatcaactg aataaaatcc tttatcctta gtggctaatg
     2281 gatgtttgat agggttatcg gcatatttgc gatatctttc tccatcttta ctaatagcct
     2341 cttcgtggaa ttgatgactt gttagtaatt cagttagata atgagatgcc aaagtccgta
     2401 gaaactttgt tttgaatcct ctgatatctc cccaatcgag cagttctgct tttgcttgtc
     2461 cgaattcttt taagcattgt tttctgcttt tcgtcttgtt aacttggcaa ataaaatgat
     2521 gtgcatcgct caaccttaat tctttcgtga atactctata aaaggcgttt ctaatagaga
     2581 agtcatcatc actaatcatt cgccattcgt cggcattaac catttgttta attaaccaat
     2641 agtgagcagt tgtagtataa ggagcatcaa catttaaacc atcgacaaat ctactcctat
     2701 tagtaatttt ccctaattcg tgaagataag cattcctatt ttcgctatcg ttagcggatg
     2761 gttcttgtgg ataataagac caatctaacc tatcattttt acgactaaaa gtattgagat
     2821 ggtcttcttt gaattttctt gtatcttcat ttaattcatc cattgaaata ttccaatcat
     2881 aggcaacatc agaacggaac acatatcttg ataagacctc agcagataca actatatacg
     2941 tttgcatatt aaggtcttca aaccccgtat atttctttga accttgtcct ttcttacgga
     3001 cgttatttag gtagtagtgc atcttgtccg tattaagcca catctcgtta aatttctttg
     3061 tttgaagggg ttgtgtctca tatcgttcta aaaactccaa acaacgccta tacagccact
     3121 ccagcttatg atagtaggtt ccaactccaa ttcctaaaat atcacaagta cgactgactg
     3181 aaacccttcc aacaaccatc ttagcgaaca ttggaagaat ggtgttcttt tgttggtgat
     3241 aagtagtggt ttcttctctt tttggtagaa cattagtgaa cttcttacac gccttacatt
     3301 gatagcgttg agatttgccc ctacttttcc cccttttgta aaattgcttc ggctcattga
     3361 atggggttga ttcttcttcc gagcagcctt ctttatgaaa ttgataatct ggctcaacat
     3421 cttggatgct attgatttct ataaggcgtt taatttcttc aacaacag
//
LOCUS       DAIGWC010000212         2361 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.guided.145, whole genome shotgun sequence.
ACCESSION   DAIGWC010000212 DAIGWC010000000
VERSION     DAIGWC010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.guided.145"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            complement(93..1196)
                     /locus_tag="NOB74_002883"
     CDS             complement(93..1196)
                     /locus_tag="NOB74_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI1221993.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            1748..2296
                     /gene="aac(6')"
                     /locus_tag="NOB74_002884"
     CDS             1748..2296
                     /gene="aac(6')"
                     /locus_tag="NOB74_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCI1221994.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          749 a          420 c          460 g          732 t
ORIGIN      
        1 attttgcaca actcatcagt ccttattgac aaagagccaa gaaatgtcct caatttgatg
       61 acagcctgct tgatgggggt tttagcaatt atttaactga ttttcttata tccttgctgg
      121 ctttcttgtg tagcatgata agtttctacg tcaagaatgg cctgtttaaa tttttctcgg
      181 gtgatttcat aaggcacatg tttaatatca tttgttgcca tggctttatc taagattgct
      241 tctaaatcgg tcgtgacatt gagattcatg tcggttaacg atactggaag ttggttcttt
      301 ttcataaaca catagatttt atcaaacaaa tcgaactgct gatccatcat caataaggtc
      361 agtacaccat aactgacaga tgctccgtga aggtatccct ccattttttc tagaacagtc
      421 gtaccgtaat agaatgagtg tgccatagca gaattatagt tattgttaac taaaacagaa
      481 accaatccgg tagtaacaat gatatccgaa acgacttgtt caattgcata tgagggacga
      541 tcgtcggcac tatctttcaa tgcttgcgta ccataagtca agagacgatc aatgcacatt
      601 tttccgattt ggattcctaa tctatccgtg tagcctagat catcgccacg agcagaaaaa
      661 gtagattcga cttctttgga taaagcatcg ccaatacctg cccataagta tttatcaggt
      721 gcttcggcaa taattgctgt atcaatgaag gtgtgtacag gtggttttga aggaaagaag
      781 agtccgtcca ttacgccttc ttcgttatag atgacacata ccgcagtgac gggcgaacag
      841 ttcgaaccaa tagtgggaaa ggtgaagact ggtttagcta gtttttcacc aatgactttt
      901 acagtatcgc aagcacggcc accaccgact gcaaacagga cgtctgcttt ttggacactt
      961 tcatgctgga tcaactgttc aatatttcca taagttgaat tacccccgta ccagagactg
     1021 gcgacaacct ctatttcctg tgtcaaagct acttttattt tgttttctgc ctttgaaagt
     1081 gcagtcttcc ctccaatcag cactactttt gtcccatatt ctttgacgat tccatttgct
     1141 ttttcatacg catctgttcc aatggtataa tttggtaaga aaacactttg actcatattc
     1201 atttccttct ttcttcgttg aaacgggtta aaattttaaa gagtgatcga tctgactgcg
     1261 gctgtagatg gagtagaggt gaacctaaga caggataagt gatgaataag gtggcatgaa
     1321 caccttgaaa tcatcaataa gtatcctaaa aacgaacaag tacaaaaaca ttgaaaacga
     1381 caataatgaa tttttgttcc tcttagtatt tctaccgatt ccctttgctt ttttgtaatt
     1441 atctaaaaat tctaaaaatt aagattatta tatgaaaaca ggttttattt gtcaattcat
     1501 aattggtttt ttttaaagca aaagataatc tatatcatga tgaacaaaca gagttttttc
     1561 ctccaattga tggctttcct gatctttcct attttgaata aagtgtttct gtataatttt
     1621 ttattttata agtaagataa ataatgaaag aatagagata ctgattggta gctaaagatt
     1681 tttgagcgag aacatttcgt tttttcaaaa ggactgttag aataagcaag aacaaggggg
     1741 aagacgtatg ataatcagtg aatttgaccg taataatcca gtattgaaag atcagctttc
     1801 tgatttactg agactgactt ggccggaaga atatggagac agctcggcag aagaagtaga
     1861 agaaatgatg aatccagaac gaatcgcggt agcagcggta gaccaagatg agttagtagg
     1921 atttattggt gcaatccctc aatacggtat cacaggttgg gaattgcatc cattagttgt
     1981 agaaagctcc cgacgaaaga accaaatagg tactcgatta gtcaattact tagaaaaaga
     2041 agtagcttcc agaggaggaa tcacgattta tttaggtacg gatgatttag accatggaac
     2101 aacgttaagt caaacggacc tgtatgagca tacatttgat aaagtggctt ccatccagaa
     2161 ccttcgtgaa catccgtatg aattctatga aaaattaggt tataaaatcg taggtgtctt
     2221 accaaatgca aatggctggg acaaaccgga tatttggatg gcaaaaacga ttattcctcg
     2281 accaaattct caataataaa aagaggttgt gacagaagta atcagcttca agaaataaga
     2341 aggaatttac gaaaattact t
//
LOCUS       DAIGWC010000213         1738 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V925-ENTFAE
            SAMN29456890-rid14855523.guided.153, whole genome shotgun sequence.
ACCESSION   DAIGWC010000213 DAIGWC010000000
VERSION     DAIGWC010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456890
            Sequence Read Archive: SRR19916718
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001360993.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001360993.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:08:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,886
            CDSs (total)                      :: 2,824
            Genes (coding)                    :: 2,776
            CDSs (with protein)               :: 2,776
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 28 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 10 of 48
            Pseudo Genes (multiple problems)  :: 7 of 48
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456890-rid14855523.guided.153"
                     /strain="microbial"
                     /isolate="V925-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-07-11"
     gene            48..959
                     /locus_tag="NOB74_002885"
     CDS             48..959
                     /locus_tag="NOB74_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HCI1221995.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1112..1597
                     /gene="vanZ"
                     /locus_tag="NOB74_002886"
     CDS             1112..1597
                     /gene="vanZ"
                     /locus_tag="NOB74_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HCI1221996.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
BASE COUNT          613 a          237 c          331 g          557 t
ORIGIN      
        1 aggaggacaa tttatttaca caaaattatt gacgctcccg actgaaaatg aagaagttgt
       61 tttttttatt gttattgtta ttcttaatat acttaggtta tgactacgtt aatgaagcac
      121 tgttttctca ggaaaaagtc gaatttcaaa attatgatca aaatcccaaa gaacatttag
      181 aaaatagtgg gacttctgaa aatacccaag agaaaacaat tacagaagaa caggtttatc
      241 aaggaaatct gctattaatc aatagtaaat atcctgttcg ccaagaaagt gtgaagtcag
      301 atatcgtgaa tttatctaaa catgacgaat taataaatgg atacgggttg cttgatagta
      361 atatttatat gtcaaaagaa atagcacaaa aattttcaga gatggtcaat gatgctgtaa
      421 agggtggcgt tagtcatttt attattaata gtggctatcg agactttgat gagcaaagtg
      481 tgctttacca agaaatgggg gctgagtatg ccttaccagc aggttatagt gagcataatt
      541 caggtttatc actagatgta ggatcaagct tgacgaaaat ggaacgagcc cctgaaggaa
      601 agtggataga agaaaatgct tggaaatacg ggttcatttt acgttatcca gaggacaaaa
      661 cagagttaac aggaattcaa tatgaaccat ggcatattcg ctatgttggt ttaccacata
      721 gtgcgattat gaaagaaaag aatttcgttc tcgaggaata tatggattac ctaaaagaag
      781 aaaaaaccat ttctgttagt gtaaatgggg aaaaatatga gatcttttat tatcctgtta
      841 ctaaaaatac caccattcat gtgccgacta atcttcgtta tgagatatca ggaaacaata
      901 tagacggtgt aattgtgaca gtgtttcccg gatcaacaca tactaattca aggaggtaag
      961 gatggcggaa tgaaaccaac gaaattaatg aacagcatta ttgtactagc acttttgggg
     1021 taacgttagc tttttaattt aaaacccacg ttaactagga cattgctata ctaatgatac
     1081 aacttaaaca aaagaattag aggaaattat attgggaaaa atattatcta gaggattgct
     1141 agctttatat ttagtgacac taatctggtt agtgttattc aaattacaat acaatatttt
     1201 atcagtattt aattatcatc aaagaagtct taacttgact ccatttactg ctactgggaa
     1261 tttcagagag atgatagata atgttataat ctttattcca tttggcttgc ttttgaatgt
     1321 caattttaaa gaaatcggat ttttacctaa gtttgctttt gtactggttt taagtcttac
     1381 ttttgaaata attcaattta tcttcgctat tggagcgaca gacataacag atgtaattac
     1441 aaatactgtt ggaggctttc ttggactgaa attatatggt ttaagcaata agcatatgaa
     1501 tcaaaaaaaa ttagacagag ttattatttt tgtaggtata cttttgctcg tattattgct
     1561 cgtttaccgt acccatttaa gaataaatta cgtgtaagat gtctaaatca agcaatctga
     1621 tctttcatac acataaagat attgaatgaa ttggattaga tggaaaacgg gatgtgggga
     1681 aactcgcccg taggtgtgaa gggttctgtt gcaaagtttt aaatctacta tcaaataa
//
